Systems Patents (Class 606/10)
  • Patent number: 10305244
    Abstract: Apparatuses and methods are disclosed for applying laser energy having desired pulse characteristics, including a sufficiently short duration and/or a sufficiently high energy for the photomechanical treatment of skin pigmentations and pigmented lesions, both naturally-occurring (e.g., birthmarks), as well as artificial (e.g., tattoos). The laser energy may be generated with an apparatus having a resonator with the capability of switching between a modelocked pulse operating mode and an amplification operating mode. The operating modes are carried out through the application of a time-dependent bias voltage, having waveforms as described herein, to an electro-optical device positioned along the optical axis of the resonator.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 28, 2019
    Assignee: CYNOSURE, LLC
    Inventors: Rafael A. Sierra, Mirko Georgiev Mirkov
  • Patent number: 10299960
    Abstract: Systems and methods to treat a region of a cornea of an eye having an epithelial layer disposed over a stromal layer. The system comprises a device to map a thickness of the epithelial layer over the region of the cornea to generate a map of epithelial thickness over the region, and a laser to generate a laser beam of an ablative radiation. A movable scan component is coupled to the laser to scan the laser beam over the region. A processor system is coupled to the laser and the movable scan component, and the processor system is configured to arrange pulses of laser beam to ablate the epithelial layer of the region in response to the map of epithelial thickness.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: May 28, 2019
    Inventors: Keith Holliday, Mark E. Arnoldussen
  • Patent number: 10300296
    Abstract: A swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: May 28, 2019
    Assignee: PhotoPill Medical Ltd.
    Inventors: Sharon Ben-Yehuda, Ram Ben-Yehuda
  • Patent number: 10300297
    Abstract: A light-emitting device (100) is disclosed. The light-emitting device (100) comprises a plurality of light-emitting elements (135) or light sources and a power module (120) adapted to selectively convey, supply or provide electrical power to the light-emitting elements (135). The power module (120) may be dimensioned such as to be able to power only a proper subset of the light-emitting elements (135) of the light-emitting device (100) at a given time, the subset having a maximum number of light-emitting elements (135) included therein with respect to the number of light-emitting elements (135) included in the all subsets of the light-emitting elements (135) of the light-emitting device (100).
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: May 28, 2019
    Assignee: SIGNIFY HOLDING B.V.
    Inventors: Jacobos Petrus Johannes Van Os, Tim Dekker, Gerrit Oversluizen, Paul Marcel Carl Lemmens, Frank Anton Van Abeelen, Wouter Hendrik Cornelis Spoorendonk
  • Patent number: 10295823
    Abstract: The present disclosure pertains to various embodiments of optical stimulation systems that may be configured to generate a stimulation beam capable of inducing a cutaneous sensation in a user. A position tracking system associated with the stimulation system may be configured to track a position of at least one target stimulation area. A controller may be configured to generate a control signal to selectively activate the stimulation system and to receive the position of at least one target stimulation area from the position tracking system. A beam steering system may be configured to receive input from the controller and configured to direct the stimulation beam toward the at least one target stimulation area based on the input from the controller.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: May 21, 2019
    Assignee: Pine Development Corporation
    Inventors: William J. Yu, Alexander A. Brownell
  • Patent number: 10286224
    Abstract: Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly comprising a first wall to which the lamps are affixed thereto and a second wall, closer to the patient, spaced from the first wall wherein the lamps are recessed relative thereto. The second wall comprises a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs on the first wall for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed between the first and second wall so that the reflective surface is relatively smooth and seamless towards the patient. The walls have a malleable rigidity for flexible adjustability relative to the user. The device is mounted to the user with a frame comprising an eyeglass frame or goggles including lenses for shielding the user's eyes from lamp radiation.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: May 14, 2019
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Jay Tapper, Lawrence A Blaustein, David Shuter, Eric Freitag, Charles Peter Althoff, Alistair Douglas Bramley, Daniel Joseph Shuter, Zbigniew Paul Lorenc, Allen Zadeh
  • Patent number: 10265120
    Abstract: A surgical instrument is provided for controlling control circuits for an independent energy delivery over segmented sections. The surgical instrument comprises an end effector comprising a first jaw and a second jaw, a first set of electrodes and a second set of electrodes and a slot defined between the first set of electrodes and the second set of electrodes. A cutting member configured to reciprocate within the slot. A control circuit is configured to receive information about impedance of tissue located between the first jaw and the second jaw of the end effector, provide electrosurgical energy to the first set of electrodes and the second set of electrodes and repeatedly alternate the electrosurgical energy between the first set of electrodes and the second set of electrodes at a predetermined time interval, and advance the cutting member.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 23, 2019
    Assignee: Ethicon LLC
    Inventors: David C. Yates, Frederick E. Shelton, IV, Jason L. Harris, Jeffrey D. Messerly
  • Patent number: 10254227
    Abstract: Biopsy imaging devices with an imaging stage configured to rotate and tilt a biological sample, as well as a method for using it, are described. The stage can use rotating bearings or extendible, telescoping arms. The device has a white light for taking normal pictures and a near-infrared laser light for causing a fluorescence-biomolecule probed sample to fluoresce for fluorescence images in a light-tight housing. A set of both types of pictures are taken from angles around, above, and below the biopsy sample with one or more cameras to generate a 3-D model in a computer of the biopsy with fluorescence markings. The 3-D model can then be rendered and viewed on a display by a surgeon to determine if sufficient margins were removed from the patient.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: April 9, 2019
    Assignee: LI-COR, Inc.
    Inventor: Han-Wei Wang
  • Patent number: 10213340
    Abstract: Systems and methods for increasing the amplitude of accommodation of an eye, changing the refractive power of lens material of a natural crystalline lens of the eye, and addressing presbyopia are is provided. Generally, there are provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of laser shots, which are in precise and predetermined patterns results in the weakening of the lens material.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: February 26, 2019
    Assignee: Lensar, Inc.
    Inventors: Gary P. Gray, Rudolph W. Frey
  • Patent number: 10213258
    Abstract: A medical laser system in accordance with one or more further embodiments includes a crystal-based laser, a power supply for powering the crystal-based laser, a controller operably connected to the crystal-based laser and the power supply, and a memory operably connected to the controller. The controller is programmed to: (a) activate the crystal-based laser to cause a laser light emission by controlling power supplied by the power supply to the laser responsive to a user activation input; and (b) record data in the memory identifying a power level, number of pulses, and duration of the laser light emission.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: February 26, 2019
    Assignee: Lymol Medical, Inc.
    Inventor: Libor Krupica
  • Patent number: 10195083
    Abstract: A method for creating cuts in a transparent material using optical radiation, wherein the optical radiation is focused at a focus in the material and the focus is displaced along a trajectory, wherein a periodic, crossing Lissajous figure is used as trajectory as viewed perpendicular to a main direction of incidence at the radiation.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: February 5, 2019
    Assignee: Carl Zeiss Meditec AG
    Inventors: Michael Bergt, Gregor Stobrawa
  • Patent number: 10179071
    Abstract: System and method for generating patterns P of aiming and treatment light on target eye tissue (e.g. the retina) of a patient's eye. The system includes light sources for treatment and aiming light, a scanner for generating patterns of spots of the generated light, a controller, and a graphic user interface that allows the user to select one of several possible spot patterns, adjust the spot density and/or spot size, and apply patterns with fixed or varied density. The patterns can be formed of interlaced sub-patterns and/or scanned without adjacent spots being consecutively formed to reduce localized heating. Partially or fully enclosed exclusion zones within the patterns protect sensitive target tissue from exposure to the light.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: January 15, 2019
    Inventors: David Haydn Mordaunt, George Marcellino, Michael W. Wiltberger, Justin Hendrickson, Katrina Bell, Dan E. Andersen
  • Patent number: 10159602
    Abstract: Embodiments of the invention provide a method and apparatus for laser-processing a material. In the embodiments, a diffraction-limited beam of pulsed laser radiation is diffracted by a diffraction device to generate a diffracted beam. The diffracted beam is subsequently focused onto the material and is controlled in time and space to irradiate the material at a target position with radiation from a set of radiation pulses of the diffracted beam so that each radiation pulse from the set of radiation pulses is incident at the target position with a cross-sectional portion of the diffracted beam, the cross-sectional portion including a local intensity maximum of the diffracted beam. The beam cross-sectional portions of at least a subset of the pulses of the set include each a different local intensity maxi-mum. In this way, a multi-pulse application for generating a photo-disruption at a target location of the material can be implemented.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: December 25, 2018
    Assignee: Wavelight GmbH
    Inventors: Klaus Vogler, Christof Donitzky
  • Patent number: 10098784
    Abstract: A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: October 16, 2018
    Assignee: Carl Zeiss Meditec AG
    Inventors: Martin Wiechmann, Michael Bergt, Mark Bischoff, Markus Sticker, Gregor Stobrawa
  • Patent number: 10076671
    Abstract: A process for using a retinal photostimulation device involves limiting multiple or repeated uses of the device during a particular treatment cycle. Ordinarily a physician would not want to repeat multiple photostimulation treatments on a patient in a short period time. The process would prevent such retreatment during a single treatment cycle where the retina for any subsequent treatment biometrically matches the retina for an earlier treatment. Such subsequent treatments would be permitted within a predefined period of time after the earlier treatment. Such subsequent treatment may also be permitted where the retinas do not biometrically match.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: September 18, 2018
    Assignee: Ojai Retinal Technology, LLC
    Inventors: Jeffrey K. Luttrull, Benjamin W. L. Margolis
  • Patent number: 10071259
    Abstract: An optical assembly includes an output optical element having a thermally conductive and optically transmissive material and a thermal conduit in thermal communication with the output optical element and having at least one surface configured to be in thermal communication with at least one heat dissipating surface of a light delivery apparatus. The optical assembly further includes a coupling portion configured to be placed in at least two states. In a first state, the coupling portion is attached to the apparatus such that the at least one surface of the thermal conduit is in thermal communication with the at least one heat dissipating surface. In a second state, the coupling portion is detached from the apparatus after having been attached to the apparatus in the first state and in which the coupling portion is configured to prevent re-attachment of the coupling portion to the apparatus.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: September 11, 2018
    Assignee: Pthera, LLC
    Inventors: Scott DeLapp, Theodore B. Hill, Rick Sorich, Scott Bradley
  • Patent number: 10052154
    Abstract: In an embodiment, an apparatus and method are described for ablating tissue in response to determining a fluorescence condition. An excitation light source may produce excitation light at a excitation wavelength of a fluorophore. A beam scanner may direct the excitation light towards a tissue location. A fluorophore may produce emission light in response to absorbing the excitation light. A camera may capture an image of the tissue location. In response to the image indicating emission light at the tissue location, an ablation light source may produce ablation light. The beam scanner may direct the ablation light towards the tissue location. Additionally or alternatively, a topography map may be generated and certain aspects of the apparatus and/or the method may be adjusted based on the topography map.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: August 21, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: Eden Rephaeli, Chia-Jean Wang
  • Patent number: 10039477
    Abstract: The present application is directed towards method and systems for determining appropriate morphology changes of an eardrum to restore sensor neural hearing. The methods include receiving a measurement of an audibility threshold, a map of a surface area of an eardrum of the patient, and an impedance of the eardrum of the patient. The methods further include determining, based on at least one of the audibility threshold, the map of the surface area, and the impedance, a thickness value to modify a morphology of a portion of the eardrum of the patient to improve hearing of the patient.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: August 7, 2018
    Inventor: Juan Betts
  • Patent number: 10016238
    Abstract: Provided and described herein are exemplary embodiments of apparatus, system, computer-accessible medium, procedure and method according to the present disclosure which can be used for providing laser steering and focusing for, e.g., incision, excision and/or ablation of tissue in minimally-invasive surgery. For example, an exemplary apparatus is provided that can include at least one optical element which can be configured to refract and/or diffract light provided in a structure which can be configured to be inserted into a body, where at least one of the optical element(s) is structured to receive the light at a first angle and generate a refracted and/or diffracted light at a second angle which can be different from the first angle relative to an optical axis.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: July 10, 2018
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Ricardo Toledo-Crow, Snehal Patel, Milind Rajadhyaksha
  • Patent number: 9968439
    Abstract: A system for treating a cataractous lens of a patient's eye includes a laser source for generating a light beam, a scanning system for deflecting the light beam to form a treatment pattern of the light beam, and a controller operably coupled to the laser source and scanning system and configured to operate the scanner to form the treatment pattern. The treatment pattern is a plurality of cuts in the form two or more different incision patterns for segmenting the lens tissue into a plurality of patterned pieces. The incision pattern includes: a first incision pattern including two or more crossing cut incision planes; and a second incision pattern comprising one or more laser incision each extending along a first length between a posterior and an anterior surface of the lens capsule.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 15, 2018
    Assignee: Optimedica Corporation
    Inventors: William Culbertson, Barry Seibel, Neil Friedman, Georg Schuele, Phillip Gooding
  • Patent number: 9950188
    Abstract: An apparatus for relaxing smooth muscles of a human body, capable of directly radiating light having a predetermined wavelength range for inducing relaxation of the smooth muscles onto acupuncture points related to an organ consisting of smooth muscles via an electrode probe. The apparatus includes a controller body to determine whether a light radiation mode is selected and an operation is started through direct manipulation using a switch, and output an LED driving signal to an electrode probe connection terminal; and wired and wireless electrode probes to be attached to/detached from the terminal to be electrically connected to/disconnected from the controller body, and to be driven by the driving signal to emit light having a predetermined wavelength range which increases concentration of a material for relaxing the muscles. Accordingly, the apparatus promotes blood and lymph circulation in an organ consisting of smooth muscles by relaxing those muscles.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: April 24, 2018
    Assignee: COLOR SEVEN CO., LTD.
    Inventors: Nam Gyun Kim, Kyoung Jun Park
  • Patent number: 9949753
    Abstract: Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 24, 2018
    Assignee: The Spectranetics Corporation
    Inventors: Wade A. Bowe, George Woodrow Burton, Paul Joseph Dalby, Ryan Michael Sotak
  • Patent number: 9913688
    Abstract: A method of removing tattoos or pigmented lesions by generating at least two laser pulses having a pulse width in the picosecond range, where the peak power of each pulse is less than 15 GW/cm2 and where the spacing between the pulses is less than ten nanoseconds, and directing the pulses to the tattoo or pigmented lesion to be removed.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: March 13, 2018
    Assignee: Cutera, Inc.
    Inventor: Michael Karavitis
  • Patent number: 9877654
    Abstract: Endoscopes and wands, useful for near infrared imaging, particularly for medical purposes, have transmitting members that transmit between about 95% and 99.5% of the energy at a wavelength within the infrared spectrum. The wands and endoscopes have at least one channel for transmitting and receiving light in the visible spectrum and at least one channel for transmitting and receiving light in the infrared spectrum.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: January 30, 2018
    Inventor: John C. Tesar
  • Patent number: 9814620
    Abstract: Deconvolution systems and methods based on cornea smoothing can be used to obtain an ablation target or treatment shape that does not induce significant high order aberrations such as spherical aberration. Exemplary ablation targets or treatment shapes can provide a post-operative spherical aberration that is equal to or below a naturally occurring amount of spherical aberration.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: November 14, 2017
    Assignee: AMO Development, LLC
    Inventors: Guang-Ming Dai, Anatoly Fabrikant, Dimitri Chernyak
  • Patent number: 9808314
    Abstract: A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: November 7, 2017
    Assignee: Blue Water Innovations, LLC
    Inventor: Terry Ward
  • Patent number: 9802059
    Abstract: An ophthalmological device (10) for the treatment of corneal diseases such as keratocanus and glaucoma, comprises a molding head (12), a suction body (14) and a UV lamp (15). The molding head (12) has a hollow cylindrical configuration and includes a rigid molding lens (18) for shaping the cornea of an eye (11) of a patient. The lens is curved and defines a plurality of apertures therein. The suction body (14) has a hollow cylindrical configuration. The lamp (15) is fitted to the suction body. Molding head (12) and suction body (14) together define a chamber (32) from which air is evacuated so as to induce a partial vacuum within the chamber (32) for attracting the cornea onto the lens (18). A photo-sensitizer is applied to the eye and while the cornea is held against the mold, it is irradiated with UV light by lamp (15) so as to cross-link collagen fibers in the cornea.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: October 31, 2017
    Inventor: Asher Abraham Saks
  • Patent number: 9750572
    Abstract: The present application relates to a cutting head for a device for cutting hair. The cutting head has a laser generator (2) and an optical system (3). The optical system is configured to focus a laser beam (4) generated by the laser generator and direct the laser beam along an optical axis (16) across a cutting zone (8) in the cutting head. The laser generator and optical system are configured such that, in a focus spot (15) of the laser beam, a dimension of the focus spot, a power density of the laser beam and the numerical aperture of the laser beam are such that, when a hair is received in the cutting zone, the power output of the laser generator is minimized while ensuring that, for a predetermined exposure time, the hair received in the cutting zone is cut by optical absorption. The present application also relates to a device for cutting hair and a method of controlling a cutting head for a device for cutting hair.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: September 5, 2017
    Inventors: Bastiaan Wilhelmus Maria Moeskops, Mark Thomas Johnson
  • Patent number: 9743481
    Abstract: The present invention extends to independently programmable lights for use in gloves and to gloves that incorporate such lights. Each independently programmable light of the present invention can include a programmable controller that stores logic for controlling the light such as by changing the color emitted by the light or the on/off pattern of the light. The user of the glove can modify the logic within the programmable controller to customize the functionality of the light. These modifications can be made by connecting the programmable light or a dedicated control unit that connects to each programmable light to another computer system to transfer new or updated logic to a programmable controller for controlling the lights in a custom manner.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: August 22, 2017
    Inventor: Richard J. Valenti
  • Patent number: 9737437
    Abstract: A method and apparatus for making improved surgical incisions in corrective eye surgery are provided. It was observed that a uniform elongated AK (or LRI) incision provides a non-uniform corrective effect due to non-uniform post-surgical relaxation of ophthalmic tissue. The method and apparatus leverage this observation to provide for creation of a surgical incision that is structured to be non-uniform along its length in such a manner as to at least partially counteract an expected variation in ophthalmic tissue relaxation to provide overall increased uniformity of corrective effect. An automated laser surgery system includes a laser control system configured to control laser delivery to cause selective ablation of ophthalmic tissue to provide an elongated structured incision that varies along its length in at least one of a depth, a profile, a width, and an angle of attack relative to a surface of the ophthalmic tissue.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: August 22, 2017
    Inventor: Anita Nevyas-Wallace
  • Patent number: 9693686
    Abstract: Systems, apparatuses, and methods of and for an ophthalmic visualization system are disclosed. An example ophthalmic visualization system may include a first lens positioned relative to a surgical microscope in a manner facilitating viewing of a central region of a retina through the surgical microscope during a surgical procedure. The first lens may be positionable in an optical path between an eye and the surgical microscope during the surgical procedure. The example ophthalmic visualization system may also include a second lens selectively positionable relative to the surgical microscope and the first lens in a manner facilitating viewing of a peripheral region of the retina of the eye during the surgical procedure. The second lens may be selectively positionable in the optical path such that the peripheral region is selectively viewable without changing the position of the first lens during the surgical procedure.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: July 4, 2017
    Assignee: NOVARTIS AG
    Inventors: Ronald T. Smith, Lingfeng Yu, Michael Papac, Argelio Michael Olivera, Steven T. Charles
  • Patent number: 9696893
    Abstract: A computer-implemented method for controlling a plurality of electromagnetic energy sources is disclosed. Instructions are executed on a processor to display on a computer-human interface display device a user interface region. The user interface region includes a pie-graph configured to display a total output power of the plurality of the electromagnetic energy sources. The pie-graph includes a radius that indicates the total output power and a plurality of sectors that indicate percentages of the total output power contributed by each of the plurality of the electromagnetic energy sources. An input is received via the user interface region, where the input is an interaction with the pie-graph that changes one of the radius or a sector of the plurality of the sectors. A power output of one or more of the electromagnetic energy sources is adjusted based on the input.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: July 4, 2017
    Assignee: BIOLASE, INC.
    Inventors: Dmitri Boutoussov, Glenn Empey, Jr., Ryuichi Iwamura, Danny Quang Tran
  • Patent number: 9662458
    Abstract: A catheter system includes a positioning catheter for receiving an injection needle into its lumen. Structurally, the injection needle incorporates a plurality of loops that are mounted directly onto its shaft. As the injection needle is moved in a distal direction to exit from the lumen of the catheter, the loops are individually biased to transition from a folded configuration, and into a deployed configuration. In their deployed configurations, the loops create a barrier that is oriented perpendicular to the needle. Thus, the barrier acts to limit the depth of insertion of the needle into target tissue of a patient, to a predetermined depth, and to prevent perforation of the target tissue by the catheter tip.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: May 30, 2017
    Inventor: Richard A. Schatz
  • Patent number: 9659151
    Abstract: Deconvolution systems and methods based on cornea smoothing can be used to obtain an ablation target or treatment shape that does not induce significant high-order aberrations such as spherical aberration. Exemplary ablation targets or treatment shapes can provide a post-operative spherical aberration that is equal to or below a naturally occurring amount of spherical aberration.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: May 23, 2017
    Assignee: AMO Development, LLC
    Inventors: Guang-ming Dai, Anatoly Fabrikant, Dimitri Chernyak
  • Patent number: 9660412
    Abstract: A method and system for generating femtosecond (fs) ultraviolet (UV) laser pulses enables stabile, robust, and optically efficient generation of third harmonic fs laser pulses using periodically-poled quasi-phase-matched crystals. The crystals have different numbers of periodically poled crystalline layers that enable a long conversion length without back-conversion and without a special phase-matching direction. The fs UV laser may have a high conversion efficiency and may be suitable for high power operation.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: May 23, 2017
    Assignee: Novartis AG
    Inventors: Klaus Vogler, Joerg Klenke, Johannes Loerner
  • Patent number: 9655515
    Abstract: In the field of eye tracking, greater accuracy or resolution in monitoring movement of the eye can be gained by digitizing the eye, and tracking the movement of a landmark with fixed size and a fixed location relative to the eye's local coordinate system. The edge of the iris can be used as such a fixed landmark. Through the location and or establishment of at least a portion of the outer edge of the iris and/or an iris center point, both large and small scale eye movements, including but not limited to micro-tremors, can be traced with a higher degree of accuracy. This will aid in the diagnosis of diseases, assessing state of consciousness, and defining brainstem death.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: May 23, 2017
    Assignee: NEURO KINETICS
    Inventors: John Howison Schroeder, Alexander D. Kiderman
  • Patent number: 9655781
    Abstract: There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing induced astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: May 23, 2017
    Assignee: Lensar, Inc.
    Inventors: Ramón Naranjo-Tackman, Jorge Octavio Villar Kuri, Rudolph W. Frey
  • Patent number: 9636256
    Abstract: The invention relates to a method and apparatus for calculating a laser shot file for use in an excimer laser comprising the steps of providing information with respect to a desired ablation profile, calculating the shot density of the desired ablation profile, using a cost function for placing laser shots of the excimer laser on grid positions wherein a threshold value is determined based on the calculated shot density of the desired ablation profile.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: May 2, 2017
    Inventor: Ernst Hegels
  • Patent number: 9603743
    Abstract: A device for processing material of a workpiece, the device including a pulsed processing laser, a focusing lens, a beam-deflection unit, a control unit and a confocal detector unit. The intensity of the laser radiation is variable. An imaging unit is provided to detect structures within the workpiece using electromagnetic radiation, wherein the electromagnetic radiation of the imaging unit is radiated via the beam-deflection unit and the focusing lens into the workpiece, and evaluating device is provided and compares the position of the focus of the laser radiation determined by the detector unit with the expected position of the focus in the image of the workpiece obtained by the imaging unit.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: March 28, 2017
    Assignee: ROWIAK GMBH
    Inventors: Christian Rathjen, Holger Lubatschowski, Tammo Ripken
  • Patent number: 9603956
    Abstract: A system providing effective, broad spectrum UV-C or other ionizing radiation clinical surface disinfection, high intensity UV-C light emitting diodes (LEDs) of incrementally differing wavelengths are sequentially embedded in densely packed reflective nacels (cups or pockets) forming the surface of a rotating spherical or hemispherical structure. A combination of UV-C emitter component location and activation with the rotational and reciprocal elevation functions of such structures produces complete and continuous environmental overlapping UV-C energy scattering.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: March 28, 2017
    Inventor: Paul Newham
  • Patent number: 9592155
    Abstract: The present invention provides improved methods and systems for laser beam positioning, shape profile, size profile, drift, and/or deflection calibration using an image capture device, such as a microscope camera, for enhanced calibration accuracy and precision. The methods and systems are particularly suited for iris calibration and hysteresis measurement of a variable diameter aperture. One method for calibrating laser pulses from a laser eye surgery system using an image capture device comprises imaging a known object with an image capture device. A pulsed laser beam is directed onto a calibration surface so as to leave a mark on the calibration surface. The mark on the calibration surface is then imaged with the image capture device. The laser eye surgery system is calibrated by comparing the image of the mark on the calibration surface to the image of the known object.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: March 14, 2017
    Assignee: AMO Manufacturing USA, LLC
    Inventors: Dimitri A. Chernyak, Keith Holliday, Mathew Clopp
  • Patent number: 9572880
    Abstract: Enhanced delivery of compositions for treatment of skin tissue with photoactive plasmonic nanoparticles and light, with embodiments relating to delivery devices using, for example, ultrasound. Treatments are useful for cosmetic, diagnostic and therapeutic applications.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: February 21, 2017
    Assignee: Sienna Biopharmaceuticals, Inc.
    Inventors: Todd James Harris, Alice Ann Chen Kim
  • Patent number: 9572717
    Abstract: An intraocular light probe has a mask or shield affixed at its distal end thereof which forms a directed light beam for intraocular application of light to target tissues or intraocular application of therapeutic light. The mask or shield serves to more fully focus, intensify and direct the beam toward the target tissues. The mask or shield also helps direct light away from other tissues and away from the eyes of the surgeon. By placing a light probe beneath a surgical instrument such as a phacoemulsifier or vitrector, laser, cutting instrument (e.g., scissors or knife), forceps or probe/manipulator, whether as part of or separate from an infusion sleeve, a mask or shield effect is created. This has the same benefits of directing the beam toward target tissues, away from other tissues and away from the eyes of the surgeon. The mask/shield can be removed from the fiberoptic light for sterilization.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: February 21, 2017
    Inventor: Christopher Sheldon Connor
  • Patent number: 9539143
    Abstract: Methods of correcting vision for presbyopia, including remodeling a stroma with a laser to create an intracorneal shape, where the corneal shape includes a central region with a thickness that is about 50 microns or less measured from an extension of a shape of a peripheral region of the corneal shape, wherein remodeling a portion of the stroma increases a curvature of a central portion of the anterior surface of the cornea with a central elevation change for near vision.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: January 10, 2017
    Inventors: Keith Holliday, Alan Lang
  • Patent number: 9498117
    Abstract: Deconvolution systems and methods based on cornea smoothing can be used to obtain an ablation target or treatment shape that does not induce significant high order aberrations such as spherical aberration. Exemplary ablation targets or treatment shapes can provide a post-operative spherical aberration that is equal to or below a naturally occurring amount of spherical aberration.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: November 22, 2016
    Assignee: AMO Development, LLC
    Inventors: Guang-ming Dai, Anatoly Fabrikant, Dimitri Chernyak
  • Patent number: 9486285
    Abstract: Treating skin can include delivering a beam of radiation to a target region of the skin to cause a zone of thermal injury including a lateral pattern of varying depths of thermal injury distributed along the target region. The lateral pattern includes at least one first sub-zone of a first depth of thermal injury laterally adjacent to at least one second sub-zone of a second depth of thermal injury. The first depth is greater than the second depth. The at least one first sub-zone of the first depth and the at least one second sub-zone of the second depth extend from a surface of the target region of the skin to form a substantially continuous surface thermal injury. The at least one first sub-zone of the first depth and the at least one second sub-zone of the second depth are substantially heated to at least a critical temperature.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: November 8, 2016
    Inventors: Dilip Y. Paithankar, Jayant D. Bhawalkar, James C. Hsia
  • Patent number: 9463116
    Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a conical flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: October 11, 2016
    Inventors: Daniel S. Durrie, George H. Pettit, John A. Campin
  • Patent number: 9427822
    Abstract: The invention relates to an adapter for coupling a laser treatment device to an object for treatment, whereby the adapter has an input side, which may be fixed relative to the laser treatment device, by a locking mechanism and which may be fixed to the object, for alignment of the object relative to the laser treatment device. A scanned laser beam is introduced on the input side, from the laser treatment device, along a beam path to the object with a reference structure. The reference structure lies on the beam path of the adapter and may be optically detected by means of the laser beam scanned over the region.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: August 30, 2016
    Assignee: Carl Zeiss Meditec AG
    Inventors: Mark Bischoff, Elke Ebert, Karsten Festag, Carsten Lang, Markus Sticker
  • Patent number: 9373020
    Abstract: In measurement data selection, when a vector composed of measurement data obtained for respective combinations of light emitting positions, light detection positions, and resolving times in a time-resolved waveform is given as y, a vector in which pixel values of learning image data are components is given as x, and a system matrix for calculating internal image data from the measurement data is given as A1, the vector y which meets the conditional expressions (2) and (3) min?y?00??(2), ?x?A1Ty?22??2??(3) or the conditional expression (4) min(?y?00+??x?A1Ty?22)??(4) is determined, and upon measurement of a subject, only the measurement data corresponding to nonzero components of the vector y is used to prepare the internal image data.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: June 21, 2016
    Inventors: Hiroyuki Kudo, Naoya Saito, Yukio Ueda, Kenji Yoshimoto, Yutaka Yamashita
  • Patent number: 9326700
    Abstract: A method for displaying information includes receiving a measurement with respect to an invasive probe inside a body of a subject of at least one probe parameter, selected from a group of parameters consisting of a bend angle of the probe and a pressure on the probe. Responsively to the measurement, an icon is displayed on a display screen representing the at least one probe parameter for viewing by an operator of the probe.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: May 3, 2016
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Assaf Govari, Yaron Ephrath, Andres Claudio Altmann, Nahum Kilim