Abstract: A laser ionization therapy assembly having a reservoir defined by a peripheral wall and a base; a support device having a support coupling member and a support opening; and a laser module accommodating a laser diode, the laser module having an opening and a laser module coupling member, wherein the support device is fixedly attached to the peripheral wall of the reservoir and the laser module is detachably coupled thereto, wherein the laser diode is positioned at an angle relative to the base of the reservoir so that laser light is directed through the openings of the laser module and support device to a predetermined location within the reservoir at a height of between ½ inch to 1 inch above the base, and wherein the laser light has a wavelength of between about 630 and 640 nm and a peak power of about 10 mW.

Abstract: Laser mapping imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes applying edge enhancement to edges within an exposure frame of the plurality of exposure frames. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises a laser mapping pattern.

Abstract: A cordless endoscope assembly includes a housing, an endoscope tube and an eyepiece. Electronics are housed in the housing and operable to operate one or more light sources in the endoscope, the electronics including one or more batteries and a printed circuit board. The housing includes a connector configured to removably couple with a cannula connector of a cannula when the endoscope tube is inserted through the cannula. The cordless endoscope is a disposable single use endoscope that can optionally be sterilized with an ethylene oxide (EtO) sterilization process.

Abstract: An articulating, steerable surgical probe includes an elongated, flexible transfer tube adapted for insertion into a surgical region for endoscopic laryngeal laser surgery. A lumen is defined by an interior of the transfer tube, and a laser fiber extends through the lumen for delivering a therapeutic laser signal to a distal end of the laser fiber. An articulating tip at the distal end of the transfer tube is responsive to articulating forces from a retractable tether for directing the treatment probe in a direction of the articulation, and a linkage to the tether from a control module effects controlled retraction of the tether for articulating the tip towards a surgical target, such that the articulating tip imposing a bend radius based on a signal loss through the laser fiber.

Abstract: The present invention provides a cell treatment apparatus capable of treating cells in a cell culture vessel. The cell treatment apparatus 100 according to the present invention includes a first region 1, a second region 3, and a third region 5. The first region 1 and the second region 3 are placed in succession. The first region 1 is a cell treatment chamber for treating cells. The cell treatment chamber can be closed from the outside of the cell treatment chamber and includes a culture vessel placement portion for placing a cell culture vessel. The second region 3 includes: a laser irradiation device capable of irradiating the cell culture vessel placed in the culture vessel placement portion with a laser; and a spot diameter adjustment device that adjusts a spot diameter formed in a portion to be irradiated with the laser in an object to be irradiated.

Abstract: Exemplary embodiments of apparatus, system and method can be provided to measure a flow of fluid within an anatomical structure. For example, it is possible to use at least one first probe arrangement structured to be insertable into a vessel and configured to direct at least one radiation to at least one portion of the anatomical structure. Further, it is possible to provide at least one second arrangement which configured to detect an interference between a first radiation provided from the fluid via the probe arrangement and second a second radiation provided from a reference path as a function of wavelength thereof. Further, at least one third arrangement can be provided which is configured to determine at least one characteristic of the fluid as a function of the interference.

Abstract: Provided is a swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.

Abstract: The device comprises: a laser source (7); a treatment hand-piece (13); a light guide (11) configured to convey a laser beam from the laser source to the hand-piece. The hand-piece (13) is configured to vary the inclination of the laser beam (F2) exiting from the hand-piece with respect to a longitudinal axis (A-A) of the hand-piece.

Abstract: Methods and apparatus are configures to measure an eye without contacting the eye with a patient interface, and these measurements are used to determine alignment and placement of the incisions when the patient interface contacts the eye. The pre-contact locations of one or more structures of the eye can be used to determine corresponding post-contact locations of the one or more optical structures of the eye when the patient interface has contacted the eye, such that the laser incisions are placed at locations that promote normal vision of the eye. The incisions are positioned in relation to the pre-contact optical structures of the eye, such as an astigmatic treatment axis, nodal points of the eye, and visual axis of the eye.

Abstract: The present invention relates to the field of devices for correcting or mitigating refractive errors in the eye, more particularly, to a solution in which desired improvements in eyesight are achieved as far as possible without limiting everyday activities and where performing the treatment itself involves minimum risk by use of a device for creating an aperture in an eye, the device having a control unit for a laser unit, and the control unit is designed to control the laser unit to create the aperture in a lens of the eye, wherein the aperture is used to increase the depth of field of the eye and is formed by laser-induced lesions which reduce light transmission through a lens aperture region surrounding an aperture opening.

Abstract: A method and apparatus for performing ophthalmic laser surgery using a pulsed laser beam is provided. The method includes establishing an initial cutting pattern comprising a plurality of original photodisruption points, establishing an enhanced cutting pattern comprising a plurality of enhanced photodisruption points selected to decrease potential adverse effects due to patient movement and having increased density over a fixed area as compared with the plurality of original photodisruption points, and performing an ocular surgical procedure according to the enhanced cutting pattern Enhanced cutting patterns may include circular cuts around the periphery of a capsule, vertical side cuts for lens fragmentation, raster lamellar cuts, and grid lamellar cuts. Each photodisruption point in the initial cutting pattern and the enhanced cutting pattern comprises a laser target point.

Abstract: A method for preventing, treating and/or improving a prostatic disease or disorder associated with epithelial hyperplasia and/or fibrosis, comprising: administering an effective amount of a multikinase inhibitor to a subject in need thereof, wherein the multikinase inhibitor has a certain spectrum of kinase inhibitory activity. The multikinase inhibitor is sunitinib, regorafenib, ponatinib, pazopanib, nintedanib and/or lenvatinib. The prostatic disease or disorder is selected from the group consisting of benign prostate hyperplasia and its associated lower urinary tract symptoms, fibrosis of ureters and renal pelvis, prostate adenoma, and prostatic intraepithelial neoplasia in animals and humans.

Abstract: A linear actuator includes a casing that contains a moveable shaft moved by a motor in response to a drive signal and coupled to an encoder that determines an actual instantaneous position of the shaft and forms part of a control loop that adjusts the drive signal so as to ensure accurate positioning of the shaft. A temperature sensor mounted on the shaft produces a temperature signal indicative of instantaneously measured temperature, and a temperature compensator responsive to the measured temperature for generating a negative or positive offset for correcting the drive signal so as to move the shaft to a positon that is corrected for instantaneous expansion or contraction of the shaft owing to departures of the shaft's actual temperature from a known baseline temperature.

Abstract: A device for cutting human or animal tissue including a femtosecond laser that can emit a L.A.S.E.R. beam in the form of impulses. The device directs and focuses the beam onto or into the tissue for the cutting thereof. The device further includes and element to shape the L.A.S.E.R. beam, positioned in the trajectory of the beam, and to modulate the energy distribution of the L.A.S.E.R. beam in the focal plane thereof, corresponding to the cutting plane.

Abstract: A first image of the eye is generated when the cornea of the eye is exposed to a gas. The cornea is covered with an optic of a patient interface. A second image of the eye with the patient interface over the cornea is generated. In this second image, the patient interface distorts the second image of the eye. One or more of a position or an orientation of the eye is determined in response to the first image and the second image when the patient interface has been placed over the cornea.

Abstract: A vibration therapy device that includes a housing that includes a handle portion, a head portion and a module seat defined on the head portion, an electrical source, a motor positioned in the housing, a switch for activating the motor, a push rod assembly operatively connected to the motor and configured to reciprocate in response to activation of the motor, and a therapy module removably secured to the module seat. The distal end of the push rod assembly is configured to removably receive a reciprocating attachment thereon. The therapy module at least partially surrounds the distal end of the push rod assembly.

Abstract: The present application provides a cerumen removing device, comprising a container section comprising a recovery hole and a discharge hole; a head section exposed to the outside through the recovery hole and having at least one air ejection hole; and a pump configured to discharge air to the outside through the air ejection hole.

Abstract: An active tracking system includes an imager configured to image the temperature of a biological tissue and a heating laser configured to heat regions of the biological tissue. The imager locates high-temperature regions of the biological tissue and the heating laser is controlled to point toward target regions of the biological tissue based on the located high-temperature regions. The active tracking system can be used to control a heating laser to continuously heat a target region of a biological tissue even when the target region moves relative to the heating laser. The active tracking system could allow one or more target regions of a biological tissue to be ‘tagged’ with heat by the heating laser and to be tracked even when the one or more target regions move relative to the heating laser. Devices and methods for operating such active tracking systems are also provided.

Abstract: An exemplary ultraviolet (UV) arrangement, can be provided, which can include, for example, a lumen structured to be inserted into a body of a patient and pass a percutaneous structure therethrough into the body of the patient, wherein the lumen can be configured to disperse or provide a UV radiation, and an optical arrangement coupled to the lumen, and configured to generate the UV radiation, and provide the UV radiation to the lumen to be dispersed or provided by the lumen. The lumen can include a weave of a plurality of strands. The optical arrangement can include an optical fiber(s) coupled to the lumen at one of the strands. The optical arrangement can include a plurality of optical fibers coupled to the lumen, where the optical arrangement can include a plurality of diffusing rings, and wherein each ring can be connected to one of the optical fibers.

Abstract: Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in a corneal stroma.

Abstract: This invention relates to a method, process and apparatus for disinfecting and sterilizing all types of surfaces contaminated with microorganisms and toxic substances to render both inactive. Furthermore, this invention relates to both a method and apparatus for disinfecting and/or sterilizing breathable air and then using this air to protect a confined space from external contamination. The apparatus consists of a new ultra-violet (NUV) source that is more effective than mercury based 254 nm light for destroying DNA of virus, bacteria, spores and cists. It is most effective in breaking chemical bonds in toxic gases and Biotoxins that are useful to terrorists. It is combined with other apparatus that remove particulates and byproducts sometimes produced by the NUV source and maintains positive pressure of the confined space so as to prevent the influx of air from outside the protected zone.

Abstract: There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing induced astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane.

Abstract: The present disclosure is directed to a method of determining a position of a medical instrument. The method may include inserting a first material into a body and adjacent to the medical instrument, analyzing at least one characteristic of the inserted first material, and determining the position of the medical instrument based on the analysis of the at least one characteristic.

Abstract: An apparatus is disclosed including a tool comprising a first device for generating aerosol from a target, the first device being deployed through an opening in a tubing of the tool, wherein the tubing is provided with aspiration ports or fenestrations such that the generated aerosol is aspirated into the tubing via the aspiration ports or fenestrations. The aspirated aerosol is then transferred to a mass spectrometer for subsequent mass analysis.

Abstract: An auxiliary surgical field visualization system is described, which includes an auxiliary surgical field camera, configured for acquiring an image of a field of view of a secondary surgical field, wherein the secondary surgical field includes the exterior of a patient's eye undergoing vitreoretinal surgery. The auxiliary surgical field visualization system also includes a display in electronic communication with the auxiliary surgical field camera, wherein the display is configured for receiving, from the auxiliary surgical field camera, a signal that includes the image of the field of view of the secondary surgical field, and upon receiving the signal, displaying the image of the field of view of the secondary surgical field.

Abstract: A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors.

Abstract: A presence detection system includes an infrared detector and a radar detector. A computer processor of the system is configured to receive respective signals from the infrared and radar detectors and process the signals via execution of an algorithm.

Abstract: Some embodiments are directed to an analysis unit for assessment of hair condition, including a map processor configured to at least: obtain a first follicular map representing a first plurality of hair root positions in a first videodermoscopy image, obtain a second follicular map representing a second plurality of hair root positions in a second videodermoscopy image, determine a common skin area from the first follicular map and the second follicular map, relate hair root positions in the second follicular map to hair root positions of the first follicular map in the common skin area to determine a plurality of related hair root positions, and compare a change in condition of individual hair between the first and second videodermoscopy image to determine the analysis result suitable for assessment of hair condition.

Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Abstract: Methods and systems for correcting presbyopia using a surgical excimer laser include activating the laser once and transmitting a pre-defined three dimensional ablation profile to treat presbyopia based on the single activating step.

Abstract: A planning device for generating control data for a treatment apparatus which by means of a laser device produces at least one incision surface in the cornea, and to a treatment apparatus having such a planning device. The invention further relates to a method for generating control data for a treatment apparatus which by using a laser device produces at least one incision surface in the cornea, and to a corresponding ophthalmic surgery method. The planning device is thereby provided with calculation means for defining the corneal incision surfaces, wherein the calculation means determine the corneal incision surfaces on the basis of data of a LIRIC structure and/or a refractive correction, and generate for the corneal incision surfaces a control data set for controlling the laser device, wherein the calculation means determine the corneal incision surfaces in such a manner that the LIRIC structure is enclosed by the incision surfaces.

Abstract: A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.

Abstract: An exemplary treatment system can be provided which can include a laser system configured to emit at least one laser beam, and an optical system configured to focus the laser beam(s) to a focal region at a selected distance from a surface of a tissue. The focal region can be configured to illuminate at least a portion of a target. The optical system can cause an irradiation energy transferred to the focal region of the laser beam(s) to (i) generate a plasma in a first region of the tissue adjacent to the target, and (ii) avoid a generation of a plasma in a second region of the tissue. The optical system has a numerical aperture that is in the range of about 0.5 to about 0.9. An exemplary method can also be provided to control such treatment system.

Abstract: A laser surgical method for performing a corneal incision while maintaining iris exposure below a predetermined exposure limit includes: determining an initial iris exposure based on an initial treatment scan, determining whether the initial iris exposure is less than the predetermined exposure limit; generating a revised treatment scan comprising one or more treatment scan modifying elements when the initial iris exposure is greater than the predetermined exposure limit, and scanning the focal zone of a pulsed laser beam according to the revised treatment scan, thereby performing the corneal incision, wherein the one or more treatment scan modifying elements causes the iris exposure to be smaller than the predetermined exposure limit.

Abstract: The aim of the invention is to machine a material by application of non-linear radiation. The aim is achieved by modifying the laser radiation emitted by a laser beam source with the aid of a polarization modulator in such a way that laser radiation focused into the material is polarized in a linear fashion, the direction of polarization varying across the cross section of the beam.

Abstract: An ophthalmic laser treatment apparatus for generating plasma by focusing a treatment laser beam to treat a treatment target portion of a patient's eye with the plasma includes: an irradiation optical system configured to irradiate the treatment laser beam to the patient's eye; a position adjusting unit configured to adjust a focusing position of the treatment laser beam in an optical axis direction with respect to a predetermined focusing reference position; an energy adjusting unit configured to adjust irradiation energy of the treatment laser beam; a storage unit configured to store evaluation information to evaluate a permissible combination of the focusing position and the irradiation energy with respect to the focusing position; and an evaluation unit configured to evaluate a combination of the focusing position adjusted by the position adjusting unit and the irradiation energy adjusted by the energy adjusting unit based on the evaluation information.

Abstract: Phototherapy devices for the treatment of truncal acne and scars include, for example, a body portion having a bottom surface and a top surface that is configured to hang on a person's shoulders and cover the upper back and/or chest. The body portion further having left and right shoulder portions extending forwardly from the body portion and curled downwardly to hook over a person's shoulders. The shoulder portions further define a space for a person's neck therebetween. A phototherapy lighting component is configured to emit a light from the bottom surface of the body portion and forwardly extending shoulder portions. In use, the person places the shoulder portions on their shoulders with the body portion hanging downwardly against the person's back or chest, for example, wearing the body portion like a cape or bib. Using the lighting component, a therapeutic amount of light is administered to the person.

Abstract: A dual port switching apparatus (12) comprising a connection part for mounting to a base unit (11), an input beam port to receive a main laser beam from a base unit (11) in an input optical path (22), a first output port (14) for connection to a flexible wave guide, a second output port (15) for connection to an articulated arm (16), and a switching element (56) moveable between a first position and a second position to direct an input beam to one of the first output port (14) and the second output port (15).

Abstract: This invention provides for a dermal repair system including a dermal repair device which is configured to be placed on the skin of a user. The dermal repair device is in the form of a removable silicone sheet which can be securely fixed in place and re-used after cleaning etc. The silicone sheet includes sheet sections and a housing section into which a rechargeable control unit can removably be inserted. Waveguides in the form of a dimple teardrop pattern are provided for directing radiation or light to distal ends of the sheet. The control unit includes a low-level radiation or light source from which radiation or light is directed along the sheet for a therapy regimen to treat closed wounds and scars, such as, C-section and breast surgery closed wounds and scars to improve healing and scar appearance. The system further comprises a recharging station configured for recharging the control unit.

Abstract: A method for pigment removal from skin includes sensing properties of a pigmented area of skin with a camera, communicating the properties to a controller, and sending commands from the controller to a laser system to scan the pigmented area in a random pattern with laser beams of different wavelengths in accordance with the properties so as to remove a portion of pigment from the pigmented area.

Abstract: A cellulite and fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing green light at approximately 529.6 nm, and at approximately 48,860 Lux, measurable at the array.

Abstract: The present invention relates to an infrared radiation device including a mounting (2) capable of receiving a user (9) and a covering portion (1) capable of covering the user (9), the covering portion (1) including at least one heating layer (5a, 5b, 5c) capable of emitting infrared radiation (6) in a predetermined range of wavelengths towards at least one portion of the space located between the inner surface of the beating layer (5a, 5b, 5c) and the mounting (2), the device being characterised in that said heating layer (5a, 5h, 5c) is adjusted by at least one controller (10) including power-supply means (16) supplying the power necessary for infrared emission and at least one programmer (15) determining the parameters of a radiation session, by defining pulsations that control at least one synchronous static relay (14) which supplies said heating layer (5a, 5b, 5c) with the power provided by the power-supply means (16) during the pulsations.

Abstract: The present invention relates to a medical skin wrinkle improvement device using a peak of a laser pulse wave, and more specifically, to a medical skin wrinkle improvement device using a peak of a laser pulse wave, thereby lowering the degree of carbonization of a skin tissue having the laser irradiated thereon, thus enhancing a skin generation effect and shortening recovery time.

Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.

Abstract: A method and system assist a physician in performing an ophthalmic surgery. The method includes receiving a quasi-real time image of at least a first portion of the eye. The at least the first portion of the eye includes an operating field for the ophthalmic surgery. A recommended next region and a recommended next procedure are determined based on the quasi-real time image and a computational model of the eye. An expected next result for the recommended next procedure is calculated using the quasi-real time image and the computational model. The recommended next region, the recommended next procedure and the expected result are provided to the physician.

Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Abstract: The invention relates to a controller for a surgical laser. According to the invention, the controller is adapted to control a laser in order to produce two or more three-dimensional compression zones, each comprising a plurality of lesions, inside a lens cortex of a crystalline lens of the eye using a laser pulse or multiple laser pulses, wherein the controller is adapted such that a laser can be calibrated with respect to a reference point within the lens, and each of the compression zones produced has a length in a radial direction, a depth in a direction parallel to the optical or visual axis and an average width in a direction parallel to a tangent of the lens cortex, wherein the sum of the average widths of all compression zones is 0.1 to 2 millimeter for every 1 diopter of desired gain in accommodation amplitude of the lens.

Abstract: Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.

Abstract: In a laser delivery system for an ophthalmic laser surgery system, a laser beam scanner employs a single or two MEMS micromirror arrays. Each micromirror in the array is capable of being independently actuated to rotate to desired angles. In one embodiment, one or two micromirror arrays are controlled to scan a laser beam in two directions. In another embodiment, a micromirror array is controlled to both correct optical aberrations in the laser beam and scan the laser beam in two directions. In yet another embodiment, a micromirror array is controlled to cause the laser beam to be focused to multiple focal spots simultaneously and to scan the multiple focal spot simultaneously. The ophthalmic laser surgery system also includes an ultrashort pulse laser, a laser energy control module, focusing optics and other optics, and a controller for controlling the laser beam scanner and other components of the system.

Abstract: Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.