Tip Or Other Heat Concentration Means Patents (Class 606/28)
  • Patent number: 10806451
    Abstract: A surgical instrument includes a body portion, a shaft, and an end effector that is operable to compress, staple, and cut tissue. The end effector includes and anvil and a staple cartridge. The anvil has a body and a modular releasable curved tip that connects with the body. The curved tip may be elastically deformable. The curved anvil tip and the tip of the cartridge include cooperating features that assist in gripping tissue during clamping. A separate cartridge may be provided that retains a replacement anvil tip and a replacement staple cartridge, where the replacement anvil tip and staple cartridge include the cooperating features. The separate cartridge may also include anvil tip and staple cartridge removal features to assist in removal of previously installed anvil tips and staple cartridges.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: October 20, 2020
    Assignee: Ethicon LLC
    Inventors: Jason L. Harris, Gregory J. Bakos, Frederick E. Shelton, IV
  • Patent number: 10758291
    Abstract: Cryogenic tissue ablation instruments for treating body tissue include an elongate flexible body with a proximal supply port for coupling with a pressurized coolant (e.g., liquid N2O), a supply lumen in fluid communication with the proximal supply port, and an expandable cryogenic balloon carried on a distal portion of the elongate body, the balloon having a wall defining an interior of the balloon.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: September 1, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael Fourkas, Steven Walak, Kurt Geitz, Kristine Tatsutani
  • Patent number: 10702682
    Abstract: A device for reducing pressure within a lumen includes a reservoir structured for holding a fluid therein, an injection port in fluid communication with the reservoir, a compliant body structured to expand and contract upon changes in pressure, and a conduit extending between and fluidly coupling the reservoir and the compliant body. The fluid may be a compressible or a noncompressible fluid.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: July 7, 2020
    Assignee: Aria CV, Inc.
    Inventors: John Scandurra, Karl Vollmers
  • Patent number: 10543122
    Abstract: Apparatus and methods for ocular treatment are provided. The apparatus can comprise a microcannula having a proximal end, a distal end, a cavity, and a central longitudinal axis. The apparatus can include a handle coupled to the proximal end of the microcannula. The apparatus can include multiple offices extending circumferentially about the microcannula distal end, each of the orifices defining a channel extending transverse to the central longitudinal axis, and one or more grooves about a circumference of the microcannula.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: January 28, 2020
    Inventor: Malik Y. Kahook
  • Patent number: 10456260
    Abstract: Two minimally invasive therapeutic procedures, particularly for patients with congestive heart failure, may be performed separately or together. One procedure involves providing a valved passageway through the patient's left ventricular wall at the apex of the patient's heart and advancing instruments through the valved passageway to connect the valve leaflets of the patient's heart valve, e.g. the mitral valve. The second procedure involves advancing a pacing lead and a pacing lead implanting device through a trocar in the patient's chest and implanting the pacing lead on an exposed epicardial region of the patient's heart wall. The pacing lead has a penetrating electrode which is secured within the heart wall. Improved devices for these procedures include a minimally invasive grasping device for heart leaflets, a leaflet connector with artificial cordae tendenae and a pacing lead implant instrument.
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: October 29, 2019
    Assignee: Trans Cardiac Therapeutics, Inc.
    Inventor: Omar M. Lattouf
  • Patent number: 10405916
    Abstract: A coating and devices using the coating are provided. The coating is applied in liquid form and dried or otherwise cured to form a durable adherent coating resistant to high temperatures and having optional hydrophobic properties. The coating formulation contains an aqueous formulation of silica, one or more fillers, and sufficient base, (e.g., potassium hydroxide), to have a pH exceeding about 10.5 during at least part of the formulation process. The formulation may contain a compound(s) that affects surface free energy, energy to make the cured coating hydrophobic. Such compounds include silanes containing halogens (e.g., fluorine or chlorine) and in particular silanes containing one or more hydrolyzable groups attached to at least one silicon atom and a group containing one or more halogens (e.g., chlorine or fluorine). A medical instrument (e.g., electrosurgical instrument) may be at least partially covered by a coating using the formulation.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: September 10, 2019
    Assignee: TEAM MEDICAL, LLC
    Inventors: Warren P. Heim, James Brassell
  • Patent number: 10363083
    Abstract: An energy output section outputs first electric energy so that a high-frequency current flows between electrodes through a treated target, and outputs second electric energy so that heat occurs in an end effector. A controller outputs the first electric energy at the same time as the second electric energy in at least a part of a period during which the heat is continuously denaturing the treated target from an output start of the second electric energy. The controller makes, based on judging that the treated target entered a predetermined state, an electric power of the first electric energy increased.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: July 30, 2019
    Inventors: Tomoyuki Takashino, Yusuke Takei, Kazuhiro Tanaka
  • Patent number: 10314636
    Abstract: A treatment apparatus for treating a body tissue, the treatment apparatus having a drive circuit, an electric resistance pattern, a heat transfer plate, a temperature acquisition circuit, and a controller. The controller controlling the drive circuit to supply power to the electric resistance pattern based on a target temperature of the heat transfer plate and a temperature of the electric resistance pattern acquired by the temperature acquisition circuit.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 11, 2019
    Inventor: Kotaro Nakamura
  • Patent number: 10251539
    Abstract: A hysteroscopy system includes a scope having an internal channel, a sheath removably coupled to the scope, and an outflow channel. The sheath has a distal flange extending internally towards an outer surface of the scope. The outflow channel is formed between an inner surface of the sheath and an outer surface of the scope. The distal flange forms a distal end of the outflow channel and is generally located between the scope and the sheath.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: April 9, 2019
    Assignee: COVIDIEN LP
    Inventors: Mira Sahney, Cemal Shener-Irmakoglu
  • Patent number: 10076384
    Abstract: A microwave ablation system and method is disclosed comprising a balloon catheter apparatus and a control system. The balloon catheter apparatus comprises a catheter configured to house a coaxial cable and one or more coolant channels, an inflatable balloon located at the distal end of the catheter, and an antenna positioned in the inflatable balloon and in communication with the coaxial cable. The control system comprises a fluid pump configured to introduce fluid into a proximal end of the catheter, a power amplifier capable of generating microwave energy for delivery to the target tissue zone for at least one energy application cycle ranging from 60 seconds to 600 seconds at a frequency ranging from 2.4 GHz to 2.5 GHz, and a computer system configured to monitor and/or regulate the delivery of microwave energy to the target tissue, the fluid pump, at least one sensor, and antenna reflected power.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: September 18, 2018
    Assignee: Symple Surgical, Inc.
    Inventors: Daniel Kasprzyk, Justin Preston, Seth Crozier, Sohail Desai, Roger D Watkins, Balamurugan Sundaram, Sureshbabu Sundaram
  • Patent number: 10058412
    Abstract: An implant includes first thermoplastic material portions, and second thermoplastic material portions liquefiable by mechanical vibrations and being in contact with the first thermoplastic material portions, wherein the second thermoplastic material portions preferably constitute at least a part of a surface of the implant, and wherein the first thermoplastic material portions have a glass transition temperature above an implantation temperature (about 20° C. to 40° C.), and wherein the second thermoplastic material portions either have a glass transition temperature below the implantation temperature or are able to transform non-mechanical energy into heat.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: August 28, 2018
    Assignee: WOODWELDING AG
    Inventors: Jörg Mayer, Andrea Muller, Peter Brunner
  • Patent number: 10004550
    Abstract: Catheter apparatuses, systems, and methods for cryogenically modulating neural structures of the renal plexus by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a cryo-applicator to a renal artery via an intravascular path. Cryogenic renal neuromodulation may be achieved via application of cryogenic temperatures to modulate neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: June 26, 2018
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Eric Ryba, Naomi Buckley, Benjamin J. Clark, Danny Donovan, Luke Hughes, Brian Kelly, Gwenda McMullin, Karun D. Naga, Stephen Nash, Roman Turovskiy, Lana Wooley, Denise Zarins, Mark Gelfand, Mark S. Leung
  • Patent number: 9839486
    Abstract: Surgical systems and methods are disclosed for creating a 3D model of a patient's affected area using an imaging device, using the model to determine an implant orientation and position, creating patient-matched instrumentation, placing the patient-matched instrumentation on the patient's anatomy, registering a computer-assisted surgical tool, and acquiring registration information. The methods and systems also include associating the surgical tool with a computer to perform a computer assisted surgery. Also disclosed are embodiments of patient-matched instrumentation to acquire registration information.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: December 12, 2017
    Assignee: Smith & Nephew, Inc.
    Inventors: Michael Dean Hughes, Jeffrey A. Sharp
  • Patent number: 9833278
    Abstract: A medical treatment apparatus includes a heat transfer portion, a heating chip, a temperature measurement unit and a control unit. The heat transfer portion comes into contact with a living tissue and transfers heat to the living tissue. The heating chip includes a heating region, is joined to the heat transfer portion, and heats the heat transfer portion by inputting energy to the heating region. The temperature measurement unit acquires a temperature of the heating region. The control unit controls a temperature of the heat transfer portion to a target temperature by controlling the temperature of the heating region to a temperature differing from the target temperature by an offset value which changes in accordance with an amount of the energy.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: December 5, 2017
    Inventor: Shinji Yasunaga
  • Patent number: 9801585
    Abstract: A catheterization system that includes an electrophysiologic (EP) catheter which has a lumen receiving an electrically conductive fluid delivered by a hydraulic line that is acted upon by a peristaltic pump advantageously avoids noise in intracardiac ECG signal recordings by using an electrical connection to short triboelectrical charge carried by the conductive fluid in the hydraulic line to an existing analog ground in the system. In one embodiment, the electrical connection includes an electrically conductive wire housed in the control handle and configured to provide electrical connection between the fluid and a pin on a printed circuit board housed in the control handle that is electrically connected to the analog ground. In another embodiment, the electrical connection shorts the electrically conductive fluid proximal of the control handle of the catheter.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: October 31, 2017
    Inventors: Kruti Shah, Alexander Lifshitz, Itzhak Fang
  • Patent number: 9770297
    Abstract: Apparatus and methods for segmental treatment of hollow anatomical structures using an optical fiber are disclosed. An elongate energy application device can absorb, scatter and/or reflect laser energy over a length of the elongate energy application device to thereby treat the hollow anatomical structure along one or more lengthened treatment segments.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: September 26, 2017
    Assignee: Covidien LP
    Inventors: Brady David Esch, Brian Eugene Farley
  • Patent number: 9743862
    Abstract: Systems and methods for transcutaneously implanting medical devices, such as in vivo analyte sensors, are provided. The systems and methods involve the use of introducers or inserters made of shape memory alloy (SMA) materials which are transitionable from one operative state or configuration to another operative state or configuration, wherein the transition from state to state enables the transcutaneous implantation and/or transcutaneous explantation of the medical device.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: August 29, 2017
    Inventors: Gary Ashley Stafford, Benjamin Mark Rush
  • Patent number: 9730793
    Abstract: Apparatus comprises: (A) a housing (248), percutaneously deliverable to a heart of a subject, slidable along a guidewire (242), and shaped to define at least one opening (249); (B) a guide member (250), percutaneously deliverable to the heart, percutaneously removable from the subject, couplable to the housing, and having: (i) a distal portion, comprising a chord-engaging element (252), configured to be percutaneously slidably coupled to and decouplable from at least one chordae tendineae (244), and (ii) a proximal portion, comprising a longitudinal element (251); and (C) a deployment tool, configured (i) to be reversibly coupled to a tissue anchor (50,280), (ii) to be slidably coupled to the longitudinal element of the guide member, and (iii) to anchor the tissue anchor to a papillary muscle (254) of the subject. Other embodiments are also described.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: August 15, 2017
    Assignee: Valtech Cardio, Ltd.
    Inventors: Tal Reich, Eran Miller
  • Patent number: 9717557
    Abstract: Cardiac ablation catheters and methods of use. Catheters that include an expandable membrane, an imaging member disposed within the expandable membrane, the imaging member having a field of view, a light source disposed within the expandable member adapted to deliver light towards the field of view of the imaging member, and an electrode comprising an outer conductive layer and inner light absorbing layer disposed between the electrode and the expandable membrane, the inner light absorbing layer adapted to absorb light from the light source and thereby reduce reflection of the light from the outer conductive electrode.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: August 1, 2017
    Assignee: APAMA MEDICAL, INC.
    Inventors: Amr Salahieh, Jonah Lepak, Emma Leung, Brian D. Brandt, John P. Claude, Claudio Argento, Thilaka Sumanaweera, Zak West
  • Patent number: 9510886
    Abstract: A handling device for handling an augmentation implant is proposed, comprising an elongated housing having an axial through-bore for accommodating a sonotrode of an ultrasound applicator, and a lateral opening for inserting a pin magazine with an augmentation pin, wherein the axial through-bore and the lateral opening are connected to each other. The handling device further comprises a distal implant portion for fastening a proximal end of the augmentation implant at the housing, and a proximal tool portion for driving and/or augmenting the augmentation implant.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: December 6, 2016
    Assignees: Woodwelding AG, Stryker European Holdings I, LLC
    Inventors: Helge Giersch, Jörg Mayer, Andrea Müller
  • Patent number: 9414879
    Abstract: The invention relates to devices, systems, and methods for heating tissue, including ablating a tumor, using the catalyzed heat of decomposition of hydrogen peroxide solutions. A hydrogen peroxide solution is contacted with a catalyst to decompose the hydrogen peroxide and heat the distal tip of a catheter to a temperature effective to ablate a target tissue.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: August 16, 2016
    Assignee: Cook Medical Technologies LLC
    Inventor: Jeffry S. Melsheimer
  • Patent number: 9408622
    Abstract: Various embodiments are directed to articulatable surgical instruments. Some embodiments comprise an end effector to treat tissue, where the end effector comprises an ultrasonic blade. A hollow shaft may extend proximally from the end effector along a longitudinal axis. A waveguide may extend through the shaft and may be acoustically coupled to the ultrasonic blade. The waveguide may comprise a distally positioned flange positioned within the hollow shaft proximally from the blade and may be held stationary at a first pivot point positioned within the hollow shaft proximally from the flange. A reciprocating wedge may be positioned within the hollow shaft such that distal motion of the wedge pushes the wedge between the flange and the hollow shaft, causing the ultrasonic blade to pivot about the first pivot point in a first direction.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: August 9, 2016
    Assignee: Ethicon Endo-Surgery, LLC
    Inventors: Foster B. Stulen, Zhifan F. Huang, Patrick A. Weizman, Steven P. Smolik, Carl J. Draginoff, Jr.
  • Patent number: 9351784
    Abstract: The stirring efficiency of a heating liquid which is supplied to the balloon of a balloon-equipped ablation catheter is increased to quickly uniformize the surface temperature of the balloon, and air is prevented from remaining in the balloon-equipped ablation catheter to enhance the safety of treatment which uses the balloon-equipped ablation catheter. A shaft for a balloon-equipped ablation catheter, consisting of a single pipe, wherein the shaft has two lumens which communicate from the distal end to the proximal end of the shaft, a first lumen being a guide wire passage lumen which is provided in order to allow a guide wire to pass therethrough, the second lumen being a liquid supply lumen which is provided in order to supply liquid to the inside of the balloon of the balloon-equipped ablation catheter.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: May 31, 2016
    Inventors: Takahiro Yagi, Motoki Takaoka, Akinori Matsukuma
  • Patent number: 9295570
    Abstract: A method of making a stent delivery system is provided in which a delivery catheter has a balloon that extends non-uniformly into interstices of a stent. In accordance with the method a balloon/stent/crimping tube assembly is placed in a crimping tool, the balloon is inflated, and the crimping tool is actuated to compress the stent on the outside of the balloon without application of heat or chemicals, thereby causing creases of the balloon to extend non-uniformly into the interstices of the stent. Optionally, pillows may be formed in the balloon to prevent longitudinal movement of the stent with respect to the balloon during intravascular delivery. One or more secondary crimpings also may be performed to achieve a smoother delivery profile.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: March 29, 2016
    Inventors: Michael Schwager, Martin Frei, Suk-Woo Ha
  • Patent number: 9233257
    Abstract: An electromagnetic radiation treatment regime includes identifying a target area of a patient. An electromagnetic radiation source, for example, a low frequency and/or radio frequency electromagnetic radiation source, is selected, along with treatment session parameters, such as, pulse frequency, pulse duration, electrical current, magnetic flux density, and/or treatment session exposure time. An amount of electromagnetic radiation is applied to the target area, and a response to the electromagnetic radiation in the target area is measured. Based on an evaluation of the measured response, the treatment parameters may be modified for one or more subsequent electromagnetic radiation treatment session.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: January 12, 2016
    Inventor: Jacob Zabara
  • Patent number: 9198795
    Abstract: Devices and methods are disclosed for the delivery of a compressible implant into a bodily lumen. The delivery device includes an enlarged section that is configured to house the implant during delivery thereof into a patient. In certain embodiments, the implant is kept within the delivery device in a substantially uncompressed configuration prior to the delivery thereof.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: December 1, 2015
    Assignee: HOLOGIC, INC.
    Inventors: David J. Callaghan, Jeffrey Model, Matthew LaPlaca
  • Patent number: 9179963
    Abstract: Regions of tissue having reduced electrical propagation are created in a bladder to affect its electrical or mechanical properties. To create these tissue regions, a tubular device is advanced through the urethra leading to the interior of the bladder, a distal expandable structure of the device is expanded to contact the inner wall of the bladder, and electrodes or other active energy delivery elements of the device are activated to deliver ablation energy. The electrodes or other active energy delivery elements are disposed over the expandable structure which is shaped to conform to the interior of the bladder. The inner wall of the organ is ablated in a predetermined pattern. The same or other electrodes disposed over the expandable structure can used to electrically map the bladder. This map of electrical activity can be used to create the predetermined pattern.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: November 10, 2015
    Assignee: NewUro, B.V.
    Inventors: Omry Ben-Ezra, Itzhak Avneri, Shahar Avneri
  • Patent number: 9113785
    Abstract: Systems, methods, and apparatus for providing a fluid and reduced-toxicity optical media with optical analysis and therapeutic energy delivery. An aspect of the invention provides an aqueous solution of increased-salinity of between about 1% and 35%. An increasing salinity in accordance with the invention provides improved transmissive efficiency at many wavelengths and less toxicity than many existing systems and methods. A catheter having integrated fibers for probing or treating internal lumens or other tissues can include a liquid-inflatable balloon or flushing mechanism using the solution for displacing blood or other obstructions in an optical path between the fiber and targeted tissue. Methods including spectroscopy can be employed with the solution for diagnosing medical conditions associated with diseased vessels or other tissues while reducing the risk of permanent damage resulting from the diagnosis.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: August 25, 2015
    Assignee: CORNOVA, INC.
    Inventors: S. Eric Ryan, Jing Tang, Matthew Flinders
  • Patent number: 9118885
    Abstract: A communication apparatus notifies existence of content data in a recording medium of an image processing apparatus to an external apparatus according to a request from the external apparatus. When the content data in the recording medium includes the content data having a first format, the communication apparatus notifies existence of the content data having the second format corresponding to the content data having the first format.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: August 25, 2015
    Inventor: Hideaki Ohshima
  • Publication number: 20150141976
    Abstract: An apparatus includes a body, a shaft, an ultrasonic element, and an annular clamp pad. The shaft extends distally from the body. The ultrasonic element is located at the distal end of the shaft. The ultrasonic element includes a distally presented annular face. The clamp pad is movable toward the distally presented annular face of the ultrasonic element. When tissue is compressed between the clamp pad and the distally presented annular face of the ultrasonic element, the ultrasonic element may be activated with ultrasonic energy. The resulting ultrasonic vibrations may sever and seal the tissue captured between the distally presented annular face and the clamp pad, resulting in an anastomosis. The apparatus may thus be used to join two hollow tubular tissue structures, such as portions of a gastrointestinal tract.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 21, 2015
    Inventors: Foster B. Stulen, Timothy G. Dietz
  • Publication number: 20150141810
    Abstract: A method and apparatus for treatment of pulmonary conditions, including a device having an end effector sized and shaped to contact a nerve component on the exterior of a bronchial segment and apply energy to that nerve component.
    Type: Application
    Filed: November 12, 2014
    Publication date: May 21, 2015
    Inventor: Kevin Shaun Weadock
  • Publication number: 20150133906
    Abstract: A method of treating a skin tissue area (3) having a skin surface (5) is provided. The method comprises the steps of: deforming the skin tissue area into a deformed shape comprising a plurality of folds (17) in the skin tissue area; arranging radiofrequency electrodes (13) in contact with the skin surface on opposite sides of the deformed skin tissue area; and, while maintaining the skin tissue area in said deformed shape, providing a spatially continuous radiofrequency energy flow between the radiofrequency electrodes on opposite sides of the deformed skin tissue area through the deformed skin tissue area, thereby heating at least a portion (19) of the deformed skin tissue area; and releasing the skin tissue area from said deformed shape, thereby deforming said heated portion (19) into a wave-shaped zone of heated skin tissue having a depth relative to the skin surface that varies between a minimum and a maximum value in a direction between said opposite sides.
    Type: Application
    Filed: July 9, 2013
    Publication date: May 14, 2015
    Inventors: Margaret Ruth Horton, Martin Jurna, Jonathan Alambra Palero
  • Publication number: 20150126989
    Abstract: An operation device for performing a procedure on a lumen in a body comprises: a single protection tube formed of a flexible material; first and second tube members provided in the protection tube; and first and second clamp-type effectors respectively provided at respective front ends of the first and second tube members, wherein operational wires, respectively, are inserted into the first and second tube members to connect the clamp-type effectors positioned at the front ends thereof with first and second manipulation handles positioned at rear ends thereof, wherein the first and second clamp-type effectors are manipulated by moving the operational wires using the first and second manipulation handles in front or rear directions, and wherein electric lines are connected with the first and second clamp-type effectors to electrothermally treat a lesion portion in the body.
    Type: Application
    Filed: November 3, 2014
    Publication date: May 7, 2015
    Inventor: Joon-sang KIM
  • Publication number: 20150088112
    Abstract: Methods for treating erectile dysfunction with therapeutic neuromodulation and associated systems and methods are disclosed herein. Erectile dysfunction can be characterized by the inability to develop and/or maintain an erection during sexual arousal or activity. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves innervating the penis of a patient. Sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for erectile dysfunction. Sympathetic nerve activity can be modulated along afferent and/or efferent pathways. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the nerves.
    Type: Application
    Filed: March 7, 2013
    Publication date: March 26, 2015
    Inventor: Neil Barman
  • Patent number: 8986294
    Abstract: Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: March 24, 2015
    Assignee: Medtronic Ardian Luxembourg S.a.rl.
    Inventors: Denise Demarais, Nicolas Zadno, Benjamin J. Clark, Erik Thai, Howard R. Levin, Mark Gelfand
  • Publication number: 20150080873
    Abstract: Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
    Type: Application
    Filed: November 20, 2014
    Publication date: March 19, 2015
    Inventors: Denise Zarins, Hanson Gifford, III, Mark Deem, Douglas Sutton, Howard R. Levin, Mark Gelfand
  • Publication number: 20150080874
    Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.
    Type: Application
    Filed: November 21, 2014
    Publication date: March 19, 2015
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin
  • Patent number: 8979831
    Abstract: Thermochemical ablation techniques may provide ablation of bodily tissue using chemical reaction energy. The chemical reaction energy is provided by chemical reactions including a highly reactive electrophilic reagent provided to a target tissue location.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: March 17, 2015
    Assignee: Regents of the University of Minnesota
    Inventor: Erik N. K. Cressman
  • Publication number: 20150073400
    Abstract: There is provided in accordance with an exemplary embodiment of the invention a method and/or a device of treating tissue near a first lumen comprising inserting an energy emission element into a second lumen and delivering energy in an amount sufficient to cause one or more spaced apart areas of tissue damage at preselected locations in tissue near the first lumen. There is also provided a method and/or a device for treating a carotid artery wall, for example, to reduce signal conduction. There is also provided a method and/or a device for treating a wall of a lumen in a limb, for example, to increase blood flow. There is also provided a method and/or a device for treating a wall of a heart, for example, to stop abnormal signal propagation.
    Type: Application
    Filed: April 18, 2013
    Publication date: March 12, 2015
    Inventors: Ariel Sverdlik, Yehuda Zadok, Or Shabtay, Iris Szwarcfiter, Avital Schauder, Krishna J. Rocha-Singh
  • Patent number: 8974829
    Abstract: A particle includes a ferromagnetic material, a radiopaque material, and/or an MRI-visible material.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: March 10, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Robert F. Rioux, Thomas V. Casey, II, Janel Lanphere
  • Publication number: 20150066008
    Abstract: A tissue closure device and a treatment method for closing an opening in a tissue wall are described. The tissue closure device comprises a heating element and a removable anchor having an anchor shaft and an occluding element at or near a distal end of the anchor shaft. The occluding element of the anchor is configured to be expanded and collapsed. The treatment method comprises introducing the occluding element of the anchor into a body canal through an opening in a tissue wall of the body canal, and deploying the anchor such that the occluding element expands to temporarily occlude the opening in the tissue wall. The tissue region surrounding the opening is then heated to cause shrinkage of collagen-containing tissue, thereby contracting the opening in the tissue wall. When a predefined trigger associated with the treatment method is met, the anchor is automatically undeployed and retracted from the body canal.
    Type: Application
    Filed: August 28, 2014
    Publication date: March 5, 2015
    Inventors: David Maier Neustadter, Giora Kornblau
  • Patent number: 8968390
    Abstract: The present invention relates to covered endoprosthetic devices. Covered endoprosthetic devices comprise an endoprosthesis and a sheath. The sheath comprises a central portion and outer portions, wherein the central portion preferentially restricts or causes a restriction of blood flow. Blood flow can be reduced by the central portion of the sheath by varying the permeability of the sheath or by having projections on the sheath that slow blood flow. Permeability may be provided by perforations or holes in the material of the sheath or by varying the polymer structure that makes up the sheath itself. The outer portions of the sheath do not substantially reduce blood flow. Methods of using sheath-covered endoprosthetic devices of the invention to treat aneurysms, especially aneurysms in proximity to small perforator vessels or arteries, are also encompassed.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: March 3, 2015
    Assignee: Medinol Ltd.
    Inventor: Jacob Richter
  • Publication number: 20150051594
    Abstract: Methods for treating polycystic ovary syndrome with therapeutic ovarian neuromodulation and associated systems and methods are disclosed herein. Polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate an ovarian artery of an ovary of a patient. Sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for the polycystic ovary syndrome. Ovarian sympathetic nerve activity can be modulated along afferent and/or efferent pathways. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g.
    Type: Application
    Filed: March 7, 2013
    Publication date: February 19, 2015
    Inventor: Paul Sobotka
  • Publication number: 20150025517
    Abstract: A probe treating a living tissue in cooperation with a jaw pivoting on a supporting point includes a treatment portion including a proximal end to which ultrasonic vibration generated from an ultrasonic transducer unit is transmitted; a distal end to which the ultrasonic vibration is transmitted from the proximal end; a holding surface holding the living tissue between the holding surface and the jaw; a back surface serving as a rear surface of the holding surface; a side surface extending from the proximal end to the distal end and being different from the holding surface; and a stress release portion provided between the distal end and the proximal end and on the side surface and releasing stress to stop development of a crack when the crack is produced in the holding surface or the back surface by external forces applied during the treatment of the living tissue.
    Type: Application
    Filed: July 14, 2014
    Publication date: January 22, 2015
    Inventor: Yukihiko SAWADA
  • Publication number: 20150018725
    Abstract: A method of treating pancreatic cancer includes: inserting a device into a stomach or a duodenum; securing at least a portion of the device in position relative to the stomach or the duodenum; and delivering ultrasonic energy from the device to treat a target site in a pancreas.
    Type: Application
    Filed: April 15, 2014
    Publication date: January 15, 2015
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Frank Graham Sommer
  • Publication number: 20150011988
    Abstract: An electro-mechanical surgical device, system and/or method may include a housing, at least two opposing jaw, and at least one electrical contact associated with at least one of the jaws. The electrical contact may include at least one of a bipolar electrical contact and an ultrasonic electrical contact. The electrical contact may be a row of electrodes located on one or all of the jaws. A sensor may also be associated with any tissue located between the jaws to sense and report the temperature of that tissue. A pierceable ampulla containing fluid may also be placed on at least one of the jaws so that the fluid is releasable when the jaws are in closed position and the electrode(s) pass through the tissue into the pierceable ampulla.
    Type: Application
    Filed: September 23, 2014
    Publication date: January 8, 2015
    Inventor: Michael P. Whitman
  • Publication number: 20150005694
    Abstract: Apparatus and method for ablating target tissue including a non-linear area of tissue in the left atrium of a patient. The method can include selecting an ablation apparatus having an ablator with a tissue engagement section, penetrating a chest cavity of the patient, and identifying the target tissue. The method can also include positioning the ablation apparatus adjacent to the target tissue so that the tissue engagement section can transfer ablation energy to the target tissue. The method can further include energizing the tissue engagement section with ablation energy in order to create a footprint on the non-linear area of tissue in the left atrium and to reduce an overall mass of excitable tissue in the left atrium.
    Type: Application
    Filed: July 1, 2014
    Publication date: January 1, 2015
    Inventors: David E. Francischelli, Mark T. Stewart, James R. Skarda
  • Publication number: 20140371736
    Abstract: A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.
    Type: Application
    Filed: August 27, 2014
    Publication date: December 18, 2014
    Inventors: Phillip S. Levin, Jay Caplan, Harith Rajagopalan, Mark A. Manasas, Andrew Coats, J. Christopher Flaherty
  • Publication number: 20140371735
    Abstract: A surgical instrument includes a handpiece, an elongate shaft extending distally from the handpiece, an end effector disposed at a distal end of the elongate shaft, and a firing beam. The end effector has a first jaw and a second jaw. The first jaw is pivotable toward and away from the second jaw to capture tissue. The end effector further comprises a preheating element and an electrode. The preheating element is configured to provide heat to the captured tissue, thereby increasing electrical conductivity of the tissue. The electrode is configured to seal the captured-preheated tissue by providing RF energy to the tissue. The firing beam is configured to sever the sealed tissue.
    Type: Application
    Filed: June 12, 2013
    Publication date: December 18, 2014
    Inventor: Gary L. Long
  • Publication number: 20140358137
    Abstract: A system and method for occluding a pulmonary vein. The device includes a treatment device comprising an inner balloon, an outer balloon, and a space therebetween. Delivery of fluid to the inner balloon inflates the treatment element to a first diameter. If a greater treatment element diameter is required to completely occlude a pulmonary vein, fluid is delivered to the space between the first and second balloons, which expands the second balloon and causes the treatment element to have a second diameter that is greater than the first diameter. The fluid delivered to the inner balloon and fluid delivered to the space between the balloons may be from different sources and may be delivered and exhausted independently. Once the treatment element is caused to have a diameter sufficient to completely occlude the pulmonary vein, the treatment element is activated to cool or heat ostial tissue.
    Type: Application
    Filed: May 31, 2013
    Publication date: December 4, 2014
    Inventor: Yixin HU