Heat Application Patents (Class 606/27)
  • Patent number: 11350988
    Abstract: A minimally invasive medical technique for treating lung tumors includes use of multiple ablation modalities in a single procedure. Condensable vapor ablation and electrosurgical ablation are applied to treat the surface of the tumor and to debulk inner regions of the tumor, respectively.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: June 7, 2022
    Assignee: Uptake Medical Technology Inc.
    Inventors: Erik Henne, Robert Barry, Henky Wibowo
  • Patent number: 11317964
    Abstract: A fluid supply instrument for a treatment instrument that is mounted on a grasping section of the treatment instrument capable of grasping a living tissue includes a port configured to receive a fluid, and a cover continuous to the port and configured to be covering a back surface on an opposite side of a grasping surface of the grasping section that is capable of grasping a living tissue. The cover forms a fluid channel continuous from the port in cooperation with the grasping section, and allows the fluid received from the port to flow out from between a cover edge adjacent to the grasping surface and an edge portion of the grasping surface.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: May 3, 2022
    Assignee: OLYMPUS CORPORATION
    Inventor: Akihito Kano
  • Patent number: 11311328
    Abstract: The present disclosure relates to a surgical tool for cutting and hemostasis of biological tissues. The surgical tool includes a hollow blade comprising a cutting implement residing within a hollow cavity configured to provide high-pressure steam through an apical surface. The cutting implement can operate independently or in cooperation with the provided high-pressure steam. The surgical tool of the present disclosure applies a directionally-controlled, high-pressure steam flow to a tissue region of interest. A control unit provides temperature-controlled steam at a flow-rate determined in accordance with tissue type and intended procedure.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: April 26, 2022
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Abdelaziz Matani, Mutasem Samih Matani, Ahmed Abdelkarim Mansi
  • Patent number: 11305131
    Abstract: A system for treating a diseased site in a human or animal body. The system includes a pharmaceutical carrier including one or more phosphors which are capable of emitting light into the diseased site upon interaction, a photoactivatable drug for intercalating into DNA of cells at the diseased site, one or more devices which infuse the diseased sited with the photoactivatable drug and the pharmaceutical carrier, an x-ray or high energy electron source, and a processor programmed to control a dose of x-rays or electrons to the diseased site for production of light inside the tumor to activate the photoactivatable drug.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: April 19, 2022
    Assignees: IMMUNOLIGHT, LLC, DUKE UNIVERSITY
    Inventors: Mark Oldham, Zakaryae Fathi, Wayne F. Beyer, Frederic A. Bourke, Jr., Harold Walder, Mark DeWhirst, Neil L. Spector, Paul Yoon, Justus Adamson, David Alcorta, Kim Lyerly, Leihua Liu, Takuya Osada
  • Patent number: 11259831
    Abstract: Various devices related to a therapeutic ultrasound device for use during a medical procedure to cauterize tissue are disclosed. The therapeutic ultrasound device can include an inner tube assembly and an outer tube assembly. The device can further include a tissue engagement assembly that is secured to the distal end of the inner tube and the distal end of the outer tube. The tissue engagement assembly includes a plurality of transducers configured to provide therapeutic ultrasound. The device can include a housing assembly that is secured to the proximal end of the inner tube and the proximal end of the outer tube. The housing assembly can include a handle configured to actuate the inner tube relative to the outer tube to engage and disengage the tissue engagement assembly.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: March 1, 2022
    Assignee: Novuson Surgical, Inc.
    Inventors: Stuart B. Mitchell, Eric Hadford, Daniel Baker
  • Patent number: 11259860
    Abstract: A surgical system includes a power supply, a power stage coupled to the power supply for converting electric energy to a power signal, an audio output device, a sensor, and a controller coupled to the power supply, the power stage, and the audio output device. The controller is operably coupled to the sensor. The power stage is configured to transmit the power signal to a surgical instrument such as an electrosurgical instrument or a microwave instrument. The sensor may be disposed on the surgical instrument. The controller causes the audio output device to output sensory feedback during operation of the surgical generator based on sensor signals received from the sensor during a surgical procedure.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: March 1, 2022
    Assignee: COVIDIEN LP
    Inventor: Joseph D. Brannan
  • Patent number: 11224538
    Abstract: A device for fusing two or more tissues is disclosed. The device comprises a hand held probe comprising a fluid receiving opening, a channel and an outlet in fluid communication whereby fluid passes through the channel and exits the outlet where it is directed to at least one of the two or more tissues and/or a space in-between. A disruptive emitter, in the form of a laser, is comprised on the probe which emits a force sufficient to fuse the two or more tissues. The device finds particular application to treatment of a detached retina by fusing the retina and the retinal pigmented epithelium. A method of fusing two or more tissues including a retina and underlying retinal pigmented epithelium is also disclosed.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 18, 2022
    Assignee: HERIOT EYECARE PTY. LTD.
    Inventors: Wilson J. Heriot, Andrew Bernard Metha, Bang Viet Bui
  • Patent number: 11185361
    Abstract: Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed. Systems, devices, and methods for identifying, localizing, monitoring neural traffic in the vicinity of, quantifying neural traffic in the vicinity of, and mapping neural traffic near targeted regions within a tissue mass are disclosed.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: November 30, 2021
    Inventors: Landy Toth, Robert S. Schwartz
  • Patent number: 11179187
    Abstract: An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: November 23, 2021
    Assignee: Tsunami MedTech, LLC
    Inventors: John H. Shadduck, Michael Hoey
  • Patent number: 11172974
    Abstract: A system and method for determining the optimum dose of cryotreatment to an area of target tissue to achieve isolation based on the time to effect (TTE). The system may generally include a treatment device, a sensing device, and a processor programmed to calculate the optimum dose of cryotreatment, in seconds, based on TTE. The TTE may be based on electrical signals received by the processor from the sensing device. The processor may be further programmed to automatically terminate a cryoablation procedure when the optimum dose of cryotreatment has elapsed. The optimum dose of cryotreatment may be the time, in seconds, it takes to achieve isolation, which may be the time it takes for an area of tissue to reach approximately ?20° C.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: November 16, 2021
    Inventor: Jean-Pierre Lalonde
  • Patent number: 11154352
    Abstract: Apparatus, consisting of a probe with a temperature sensor and a transducer in contact with a living subject's tissue. A power supply delivers electrical power to the transducer for tissue ablation. A controller receives a signal from the temperature sensor and in response outputs a tissue temperature. During a first time period the power supply delivers no more than a first target power to the transducer, and reduces the power when a first maximum allowable temperature of the tissue is exceeded. During a transition time period the power supply delivers no more than a second target power, while reducing the delivered power when the first maximum allowable temperature of the tissue is exceeded. During a second time period the power supply delivers no more than the second target power, while reducing the delivered power when a second maximum allowable temperature, less than the first maximum allowable temperature, is exceeded.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: October 26, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Assaf Govari, Andres Claudio Altmann, Israel Zilberman
  • Patent number: 11020165
    Abstract: An inventive system and method for touch free operation of an ablation workstation is presented. The system can comprise a depth sensor for detecting a movement, motion software to receive the detected movement from the depth sensor, deduce a gesture based on the detected movement, and filter the gesture to accept an applicable gesture, and client software to receive the applicable gesture at a client computer in an ablation workstation for performing a task in accordance with client logic based on the applicable gesture. The system can also comprise hardware for making the detected movement an applicable gesture. The system can also comprise voice recognition providing voice input for enabling the client to perform the task based on the voice input in conjunction with the applicable gesture. The applicable gesture can be a movement authorized using facial recognition.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: June 1, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Asaf Merschon, Assaf Govari, Andres Claudio Altmann, Yitzhack Schwartz
  • Patent number: 11013427
    Abstract: Methods and apparatus for the study of gastrointestinal transit in a human or animal subject. The method being for the study of a subject which has previously ingested a container containing first and second fluids that are detectable and distinguishable by MRI, which method comprises the steps of forming a first magnetic resonance image of at least a portion of the subject's GI tract in which the container is located, wherein the magnetizations of the first and second fluids are in-phase; forming a second magnetic resonance image, coincident with the first image, wherein the magnetizations of the first and second fluids are out-of-phase; and subtracting the second image from the first image, or vice versa, to form a composite image.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: May 25, 2021
    Assignee: NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST
    Inventors: Luca Marciani, Roy Harris, Caroline Louise Hoad, Penelope Anne Gowland, Alan Christopher Perkins, Mark Robert Fox, Robin Charles Spiller
  • Patent number: 10959743
    Abstract: A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: March 30, 2021
    Assignee: SHOCKWAVE MEDICAL, INC.
    Inventors: John M. Adams, Daniel Hawkins, Clifton A. Alferness
  • Patent number: 10940246
    Abstract: A system, method and apparatus for notifying a surgeon of an occlusion in an ocular surgical apparatus are disclosed herein. Through operation of a handpiece of the surgical apparatus, the handpiece may become blocked or occluded. An occlusion detector is configured to sense the occlusion in the handpiece, and an occlusion signal is generated. A control module is provided to send an occlusion warning signal to a foot pedal of the surgical apparatus, where a tactile notification is provided to a user of the apparatus that an occlusion has occurred.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: March 9, 2021
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventor: Mitchell W. Mallough
  • Patent number: 10925662
    Abstract: Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: February 23, 2021
    Assignee: COVIDIEN LP
    Inventors: Boris Chernov, Igoris Misuchenko, Georgy Martsinovskiy, Mikhail Verbitsky
  • Patent number: 10869672
    Abstract: Provided herein is an occlusion device comprising: (a) a substantially solid marker band having an inner and outer diameter, a proximal end, and a distal end; and (b) a resilient mesh body attached within the marker band, wherein the body is a length y, and wherein the body comprises a bolus of additional resilient mesh material of a length x, wherein y is greater than x, and wherein the body extends distally from the marker band having a first delivery shape and a second expandable deployed shape. Also provided herein is a kit comprising the occlusion device disclosed herein and a means for delivery thereof. Methods of manufacture and use of the occlusion device disclosed herein are also disclosed.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: December 22, 2020
    Assignee: Cents Endovascular Limited
    Inventor: Stephen Griffin
  • Patent number: 10842532
    Abstract: Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the surgical device includes a handle, an elongate inner sheath and a circular cutting blade that extends from the distal end of the sheath upon actuating the handle. The circular cutting blade is configured to engage the tissue surrounding an implanted lead and cut such tissue in a coring fashion as the surgical device translates along the length of the lead, thereby allowing the lead, as well as any tissue remaining attached to the lead, to enter the device's elongate shaft. The surgical device has a barrel cam cylinder in the handle assembly that imparts rotation of the blade and a separate cam mechanism in the tip of outer sheath assembly that imparts and controls the extension and retraction of the blade.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: November 24, 2020
    Assignee: SPECTRANETICS LLC
    Inventors: Kenneth P. Grace, Weston H. Lee, Robert Carver, Grant Donnelly Foy, Bruce A. Hoo
  • Patent number: 10842550
    Abstract: A non-invasive thermal ablation method is provided for heating a lesion area using a non-invasive thermal ablation device. The non-invasive thermal ablation method includes: generating a time-varying magnetic field in a lesion area including a liquid metal using a magnetic field-generating element of the non-invasive thermal ablation device to heat the lesion area. In addition, a non-invasive thermal ablation device for the method is also provided.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: November 24, 2020
    Inventor: Jen-Jie Chieh
  • Patent number: 10792518
    Abstract: A passive cavitation mapping method is provided that includes capturing a channel signal from at least one ultrasound transducer in an array of ultrasound transducers, isolating a cavitation signal in the channel signal, time-gating the channel signal about the cavitation signal, computing a time-delay between neighboring the cavitation signals in adjacent the channel signals, computing a modified parabolic fit to the square of the arrival times, where the modified parabolic fit includes a coordinate transformation using an x location of a leading edge of wavefronts of the cavitation signal and a maximum arrival time of the cavitation signal, extracting a location of a cavitation signal source at point (x, z) in the coordinate transformation, computing a cavitation magnitude for each non-eliminated cavitation signal, creating a passive cavitation map by convolving the cavitation magnitude and the source location with an uncertainty function, and using the cavitation map for therapeutic ultrasound applications
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: October 6, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Taehwa Lee, Juergen K. Willmann, Jeremy Joseph Dahl
  • Patent number: 10773095
    Abstract: Devices and methods for identifying and destroying cancer cells are disclosed. Devices and methods may relate to techniques of imaging and/or irradiating cells bearing a plurality of surface-modified superparamagnetic iron oxide nanoparticles (SPIONs) therein. Imaging can be realized with a magnetic imaging device that generates an imaging magnetic field. A magnetic field associated with the SPION-bearing cancer cells and resulting from imaging, can be detected with a detection device. Irradiation can be realized with a magnetic field emission device that generates an irradiation magnetic field such that the SPIONs in the SPION-bearing cells are heated as a result of said magnetic field, thereby killing the SPION-bearing cells. The magnetic imaging device may be used as the magnetic field emission device. The magnetic fields produced for imaging and/or irradiating, as well as the associated magnetic field, can be focused using one or more magnetic metalens devices.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: September 15, 2020
    Assignee: LOCKHEED MARTIN CORPORATION
    Inventors: Christina Drake, Clara Baleine
  • Patent number: 10653472
    Abstract: An inventive system and method for touch free operation of an ablation workstation is presented. The system can comprise a depth sensor for detecting a movement, motion software to receive the detected movement from the depth sensor, deduce a gesture based on the detected movement, and filter the gesture to accept an applicable gesture, and client software to receive the applicable gesture at a client computer in an ablation workstation for performing a task in accordance with client logic based on the applicable gesture. The system can also comprise hardware for making the detected movement an applicable gesture. The system can also comprise voice recognition providing voice input for enabling the client to perform the task based on the voice input in conjunction with the applicable gesture. The applicable gesture can be a movement authorized using facial recognition.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: May 19, 2020
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Asaf Merschon, Assaf Govari, Andres Claudio Altmann, Yitzhack Schwartz
  • Patent number: 10603891
    Abstract: Method for producing an object by additively manufacturing a preform of the object from a building material comprising a polymer. The preform is encapsulated with a metal or metal alloy encapsulant that is capable of withstanding temperatures greater than the preform. The encapsulated preform is heated at a predetermined temperature and for a period of time, such that the preform at least partially transmutes into the form of a carbonaceous solid.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: March 31, 2020
    Assignee: Hexcel Corporation
    Inventors: Scott DeFelice, Anthony DeCarmine
  • Patent number: 10575904
    Abstract: Device and method for selectively ablating a submucosal layer of a duodenal wall and/or of sensory neurons therein, including a laser transmitting element coupled with the catheter body and configured to transmit a laser beam having a spot diameter of less than 200 microns and to provide an ablative dose of 0.5-2.5 J/mm; wherein the laser beam is configured to selectively ablate an area of the submucosal layer that is at least twice the size of the spot diameter, while essentially preventing damage of the surrounding mucosal, muscularis and/or serosal layers of the duodenal wall; and an expandable member configured to stretch the duodenal wall and to generate a fixed distance between the catheter's laser transmitting element and the duodenal wall.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: March 3, 2020
    Assignee: DIGMA MEDICAL LTD.
    Inventors: Ilan Ben Oren, Boaz Behar
  • Patent number: 10575901
    Abstract: Described embodiments include an apparatus that includes an electrical interface and a processor. The processor is configured to receive, via the electrical interface, a temperature sensed by a temperature sensor at a distal end of an intrabody probe, to estimate a temperature of tissue of a subject, based on the sensed temperature and a parameter of an ablating current driven, by an ablation electrode at the distal end of the intrabody probe, into the tissue, and to generate an output in response to the estimated temperature. Other embodiments are also described.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: March 3, 2020
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Assaf Govari, Andres Claudio Altmann, Assaf Pressman, Dror Berman
  • Patent number: 10543093
    Abstract: Methods and tools capable of treating diffuse or localized pain attributable to fluid accumulation within a bone. Such methods may utilize an instrument that includes a pilot adapted to penetrate soft tissue between the bone and the skin of a living being. The pilot is used in combination with a penetration tool to penetrate the bone, penetrate into the cortex of the bone, and form a seal against the surface of the bone, and after which fluid is removed from within the bone. Alternatively, the method may utilized a penetration tool equipped with a stopper bar to limit penetration to the periosteum of the bone, and/or may be implanted and connected to an implanted pump.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: January 28, 2020
    Inventor: Dmitry Arbuck
  • Patent number: 10515831
    Abstract: A biocompatible medical device can be at least partially implantable into a living human or animal subject to provide active treatment of biofilm that can occur use within the subject. The medical device can include a catheter, including an interior conduit capable of permitting fluid flow. A heating device can be located on a portion of the catheter to be located within the subject, the heating device including at least a pair of electrodes having a variable spacing therebetween, the variable spacing specified to allow heat to be generated using a time-varying electromagnetic input signal providing a variable frequency to control a variable location along the electrodes at which heat is generated, such as can provide a virtual matrix of local heat sources.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: December 24, 2019
    Inventor: Anand Deo
  • Patent number: 10502340
    Abstract: A system for checking high fluid pressure and low fluid pressure limit switches for valves and fluid supply to a fluid consumption appliance. The system may incorporate one or more pressure sensors at a fluid valve to detect an amount of fluid pressure. The one or more pressure sensors may be connected to a processor. The high fluid pressure and low fluid pressure sensor limit switches may also be connector to the processor. A display and user control may be connected to the processor.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: December 10, 2019
    Assignee: Honeywell International Inc.
    Inventors: Karen Karg, Pallavi Dharwada, Henry Nahurski, Donald J. Kasprzyk
  • Patent number: 10485697
    Abstract: A device for topical cooling of the nervous system via cooling of cerebrospinal fluid, or CSF, using a solid thermally conductive material. The solid thermally conductive material is coupled to a heat exchange apparatus. The thermally conductive material may be coupled to any catheter that is used in existing clinical standard of care for acute neuronal injuries, such as catheters used to monitor and relieve intracranial pressure. The thermally conductive material is a biocompatible and solid material, for instance, metals such as steel, tungsten and titanium, and non-metallic materials such as thermal diamond paste.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: November 26, 2019
    Assignee: GREAT CIRCLE TECHNOLOGIES, INC.
    Inventor: Sanjay Dhall
  • Patent number: 10441769
    Abstract: In some embodiments, the present disclosure pertains to a method of delivery of an active agent to a target tissue, in a subject in need thereof comprising positioning a high intensity focused ultrasound transducer to enable delivery of ultrasound energy to the target tissue. Such a method comprises energizing the high intensity focused ultrasound transducer; imaging at least a portion of the target tissue; and discontinuing delivery of ultrasound energy. Further, such a method may comprise administering the active agent to the subject under the conditions of thermal stimulation. In another embodiment, the present disclosure relates to a method of treating a tumor in a subject in need thereof comprising administering a therapeutic agent to the subject and providing thermal stimulation to the tumor. In some embodiments, there is provided a method for increasing the efficacy of a therapeutic agent in a target tissue.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: October 15, 2019
    Assignees: UNIVERSITY OF HOUSTON, ST. LUKE'S EPISCOPAL HOSPITAL
    Inventors: Pei-Herng Hor, Raja Muthupillai, Jiming Zhang
  • Patent number: 10406228
    Abstract: Iron oxide nanoparticle compositions, methods of preparing the nanoparticles using high gravity controlled precipitation (HGCP), and methods of using the nanoparticles are disclosed.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: September 10, 2019
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventor: Robert Ivkov
  • Patent number: 10398497
    Abstract: A surgical tool including a lockout mechanism is provided. The surgical tool may include an instrument mounting portion including a shaft assembly coupled to and extending distally from the instrument mounting portion and an end effector including a reciprocatable element coupled to a distal end of the shaft assembly. The surgical tool may further include an energy source configured to deliver energy to the end effector and an actuation mechanism configured to actuate the end effector. The actuation mechanism may be configured to reciprocate the reciprocatable element of the end effector. The lockout mechanism may be operably interfaced with the actuation mechanism to control reciprocating movement of the reciprocatable element.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: September 3, 2019
    Assignee: Ethicon LLC
    Inventors: Jonathan T. Batross, Gregory A. Trees, Foster B. Stulen, Randolph Stewart, Chad P. Boudreaux
  • Patent number: 10315055
    Abstract: HIFU treatment of localized prostate cancer includes identifying the cancer locations in a patient's prostate and visually segmenting the patient's prostate into areas for analysis and treatment. The section including the most aggressive cancer is determined to be the primary area and subjected to a first full HIFU treatment for a period intended to ablate the cancer. HIFU treatment is then stopped on the primary area, allowing it to rest, while simultaneously subjecting the next contiguous area of the prostate to HIFU treatment to ablate any additional areas of suspected cancer. HIFU treatment is then stopped in the contiguous area. The primary area is then subjected to a second full HIFU treatment for a period sufficient to ensure the complete ablation of the cancerous tumor. Repeating alternating full HIFU treatment on subsequent contiguous areas of the prostate ensures the complete ablation of any cancerous tumors in the prostate.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: June 11, 2019
    Inventor: Ronald E. Wheeler
  • Patent number: 10231770
    Abstract: A system for use in tumor ablation. The tumor ablation system includes a microwave antenna which has a channel along the length thereof. There are two ports proximate the proximal end of the microwave antenna. The first port is an energy port configured to connect the antenna to an energy source. The second port is a fluid port configured to connect the channel to a fluid delivery mechanism. The system also includes an inflatable balloon configured to be attached to a distal end of the antenna. The channel permits fluid access from the fluid port to an interior of the balloon for inflation thereof.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: March 19, 2019
    Assignee: Medtronic Holding Company Sárl
    Inventor: Calin Druma
  • Patent number: 10194970
    Abstract: A vapor delivery system and method is provided that includes a number of features. In one embodiment, a method comprises inserting a vapor delivery needle into tissue of a patient, activating a flow of vapor from a vapor generator through vapor delivery ports of the vapor delivery needle to cause condensed liquid to exit vapor delivery ports of the vapor delivery needle, generating vapor in the vapor generator, delivering a dose of vapor through the vapor delivery ports of the vapor delivery needle into the tissue, and after the dose of vapor is delivered, re-activating the flow of vapor from the vapor generator through the vapor delivery ports of the vapor delivery needle to prevent a vacuum from forming in the vapor delivery needle. Vapor therapy systems are also provided.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: February 5, 2019
    Assignee: NxThera, Inc.
    Inventors: Roger Noel Hastings, Michael Hoey, Steven Carlson, Matthew Byrne
  • Patent number: 10172939
    Abstract: Apparatus and methods are described for use with a subject suffering from cancer. A nanoparticle (22) includes an inner core (30) that comprises a phase-change material that is configured to absorb latent heat of fusion by undergoing a phase change. An outer layer (32) disposed around the inner core includes a plurality of nano-spheres (34) of at least one metal, and a plurality of molecules (38) of a substance that binds preferentially with cancerous cells relative to non-cancerous cells. The nanoparticle has a volume of at least 65,000 nm3 and is elongatable into an ellipsoid, such that, when the nanoparticle is maximally elongated, each of the semi-axes defined by the ellipsoid is greater than 5 nm, and at least two of the semi axes of the ellipsoid are less than 30 nm. Other applications are also described.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 8, 2019
    Assignee: NEW PHASE LTD.
    Inventors: Raphael Hof, Raz Khandadash, Ella Fremder
  • Patent number: 10156818
    Abstract: A fixing device includes a fixing rotator being rotatable and a heater to heat the fixing rotator. The heater includes a tube, a heat generator, disposed inside the tube, to generate heat, and a sealing portion, disposed at each lateral end of the tube in a longitudinal direction of the heater, to seal the tube. The sealing portion includes an inboard edge. A reflector reflects heat radiated from the heater toward the fixing rotator. The reflector includes an outboard edge being disposed inboard from the inboard edge of the sealing portion in an axial direction of the fixing rotator.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: December 18, 2018
    Assignee: Ricoh Company, Ltd.
    Inventors: Yasunori Ishigaya, Kazuya Saito, Keitaro Shoji, Toshihiko Shimokawa, Hiromasa Takagi
  • Patent number: 10143519
    Abstract: A method of treating a patient is described herein. The method can include the steps of identifying a target that contains biological tissue and directing one or more pulses of electromagnetic radiation at the target. The pulses of electromagnetic radiation can cause a temperature increase per unit of time in the biological tissue. Additionally, the temperature increase per unit of time can cause the change in the cell function in the biological tissue and can be within a range of approximately one degree Celsius per second to approximately one degree Celsius per microsecond.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: December 4, 2018
    Assignee: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Karl H. Schoenbach, Shu Xiao
  • Patent number: 10064676
    Abstract: A medical apparatus includes a first clamp portion; a pivot shaft; a second clamp portion rotatable around the pivot shaft, and movable between an opened position in which the second clamp portion is distant from the first clamp portion, and a closed position in which the second clamp portion is adjacent to the first clamp portion; and an electrode member provided on the second clamp portion, and opposed to the first clamp portion, the electrode member forming a clearance in cooperation with the first clamp portion in the closed position, the clearance in a second position distant from the pivot shaft being smaller than the clearance in a first position adjacent to the pivot shaft, to adjust holding pressure.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: September 4, 2018
    Assignee: OLYMPUS CORPORATION
    Inventor: Yuji Hirai
  • Patent number: 10058372
    Abstract: Tissue ablation devices and methods including needle injectors that deliver flowable thermal treatment media into an interface with tissue and that can provide a single dose of ablative energy.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: August 28, 2018
    Inventor: John H. Shadduck
  • Patent number: 10052147
    Abstract: An inventive system and method for touch free operation of an ablation workstation is presented. The system can comprise a depth sensor for detecting a movement, motion software to receive the detected movement from the depth sensor, deduce a gesture based on the detected movement, and filter the gesture to accept an applicable gesture, and client software to receive the applicable gesture at a client computer in an ablation workstation for performing a task in accordance with client logic based on the applicable gesture. The system can also comprise hardware for making the detected movement an applicable gesture. The system can also comprise voice recognition providing voice input for enabling the client to perform the task based on the voice input in conjunction with the applicable gesture. The applicable gesture can be a movement authorized using facial recognition.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: August 21, 2018
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Asaf Merschon, Assaf Govari, Andres Claudio Altmann, Yitzhack Schwartz
  • Patent number: 10039917
    Abstract: Example adjustable electrodes are described. One example adjustable electrode includes two or more contacts configured to selectively deliver high frequency alternating current (HFAC) to a nerve in an amount sufficient to produce an HFAC nerve conduction block in the nerve. The example adjustable electrode may also include a logic configured to selectively control which of the two or more contacts deliver HFAC to the nerve to control whether the nerve electrode is in a first (e.g., onset response mitigating) configuration or in a second (e.g., HFAC nerve conduction block maintenance) configuration. The electrode may be used in applications including, but not limited to, nerve block applications, and nerve stimulation applications. The electrode may be adjusted by changing attributes including, but not limited to, the number, length, orientation, distance between, surface area, and distance from a nerve of contacts to be used to deliver the HFAC.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: August 7, 2018
    Assignee: Case Western Reserve University
    Inventors: Kevin Kilgore, Douglas Michael Ackermann, Jr., Niloy Bhadra, Narendra Bhadra, Joe Payer
  • Patent number: 9993665
    Abstract: A treatment instrument includes: a proximal side probe transmits ultrasonic vibration from its proximal end to its distal end; a distal side probe configured to transmit the ultrasonic vibration from its proximal end to a treatment portion at its distal end; and a holding portion which holds a state where the proximal end of the distal side probe is into collision with the distal end of the proximal side probe, and a state where vibration is transmittable from the proximal end of the proximal side probe to the distal end of the distal side probe.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: June 12, 2018
    Assignee: OLYMPUS CORPORATION
    Inventors: Hideo Sanai, Kenichi Kimura
  • Patent number: 9993666
    Abstract: Apparatus comprising an ultrasound ablation system, which comprises a reflection-facilitation element, configured to be placed at an extramyocardial site of a subject, and to provide an extramyocardial reflective region; and an ultrasound tool, which comprises at least one ultrasound transducer configured to be positioned within a heart chamber of the subject. The ultrasound transducer is configured to ablate myocardial tissue by applying ultrasound energy to the myocardial tissue such that at least a portion of the transmitted energy is reflected by the reflective region onto the myocardial tissue. Other embodiments are also described.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: June 12, 2018
    Assignee: RAINBOW MEDICAL LTD.
    Inventors: Liat Tsoref, Yossi Gross, Michael Kardosh
  • Patent number: 9971004
    Abstract: A method and programmable computer system calculates and displays the regions where the temperature can be reliably measured in a thermal therapy procedure. The clinician or automated control system then can make an informed decision to treat these regions or plan a treatment to avoid them based on the sensitivity of surrounding structures to unintended heating.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: May 15, 2018
    Assignee: Profound Medical, Inc.
    Inventors: Ron Kurtz, Kee Tang, Mathieu Burtnyk
  • Patent number: 9943353
    Abstract: Methods, systems and devices for applying energy to tissue, and more particularly relates to a system for ablating or modifying structures in a body with systems and methods that generate a flow of vapor at a controlled flow rate for applying energy to the body structure.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 17, 2018
    Assignee: Tsunami MedTech, LLC
    Inventors: Michael Hoey, John H. Shadduck
  • Patent number: 9940747
    Abstract: A method for mapping a 3D surface that contains a volume in space, the method including: acquiring 3D vertices representing the surface, and defining in the space a first plane cutting the volume and a second parallel plane, external to the volume, thereby partitioning the vertices into a first set not between the two planes and a second set located between the two planes. The method further includes projecting the first set vertices onto the first plane so as to generate first projected points therein, and projecting the second set vertices onto the first plane while translating these vertices in respective directions parallel to the second plane by respective translations responsive to respective distances of the second vertices from the first plane, thereby generating second projected points in the first plane. The first and second projected points are displayed as a 2D representation of the surface on a screen.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: April 10, 2018
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Natan Sharon Katz, Lior Zar, Aharon Turgeman
  • Patent number: 9931134
    Abstract: A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: April 3, 2018
    Assignee: Medtronic, Inc.
    Inventors: James B. Hissong, Mark T. Stewart, David E. Francischelli, James R. Keogh, Hotaik Lee, Nadine B. Smith, James R. Skarda
  • Patent number: 9931154
    Abstract: An inventive system and method for touch free operation of an ablation workstation is presented. The system can comprise a depth sensor for detecting a movement, motion software to receive the detected movement from the depth sensor, deduce a gesture based on the detected movement, and filter the gesture to accept an applicable gesture, and client software to receive the applicable gesture at a client computer in an ablation workstation for performing a task in accordance with client logic based on the applicable gesture. The system can also comprise hardware for making the detected movement an applicable gesture. The system can also comprise voice recognition providing voice input for enabling the client to perform the task based on the voice input in conjunction with the applicable gesture. The applicable gesture can be a movement authorized using facial recognition.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: April 3, 2018
    Assignee: Biosense Webster (Israel), Ltd.
    Inventors: Asaf Merschon, Assaf Govari, Andres Claudio Altmann, Yitzhack Schwartz
  • Patent number: 9814521
    Abstract: An ablation catheter arrangement includes an ablation generator, a rinsing liquid source for providing a liquid for rinsing the treatment area in which ablation is performed, and an ablation catheter connectable to the ablation generator and to the rinsing liquid source. The ablation catheter has an ablation area, at least one rinsing opening, and a rinsing bath for supplying rinsing liquid to the treatment area. A blood pressure measurement device detects the intracardiac blood pressure over the liquid column of the rinsing liquid, and communicates with the rinsing channel of the ablation catheter by fluid connection.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: November 14, 2017
    Assignee: VASCOMED GMBH
    Inventor: Wolfgang Geistert