Abstract: In some examples, a laser-based ophthalmological surgical system (hereinafter “system”) includes a therapeutic radiation source configured to emit therapeutic radiation with a first wavelength. The system may also include a probe radiation source configured to emit probe radiation with a second wavelength different than the first wavelength. The system may also include one or more optical elements configured to direct the therapeutic radiation and the probe radiation into an eye of a patient and to collect reflected probe radiation from the eye of the patient. The reflected probe radiation may be indicative of an amount of therapeutic radiation exposure of the eye of the patient. The system may also include a photodetector configured to receive the reflected probe radiation from the one or more optical elements and to generate a photocurrent indicative of the amount of therapeutic radiation exposure of the eye of the patient.

Abstract: An ophthalmic surgical laser system includes: a laser that produces a pulsed laser beam having a pulse energy and pulse repetition rate; a high frequency fast scanner; an XY-scan device; a Z-scan device; and a controller. The controller controls the high frequency scanner to produce a scan line having a scan width; controls the XY-scan device and the Z-scan device to carry out of first sweep of the scan line in a first sweep direction and to carry out a second sweep of the scan line in a second sweep direction that is not parallel to the first sweep direction thereby defining an overlap region. At least one of the pulse energy, repetition rate, XY-scan speed, and the scan width is varied so as to accelerate the cutting speed and reduce the exposure of ophthalmic tissue in the overlap region to multiple exposures of laser pulses configured to modify ophthalmic tissue.

Abstract: A laser instrument for therapy on the human eye, designed for surgery of the cornea, the sclera, the vitreous body or the crystalline lens, especially suitable for use in immediate succession with other instruments for eye diagnosis or eye therapy, in such a way that during the alternating use of the various instruments, the eye or at least the patient preferably remains in a predetermined position and alignment within one and the same treatment area.

Abstract: A surgical robotic system offers automation templates, such as surgical task templates, for collaborative control of the robot arms operating in an automated manner. This automated operation through integration of template selection and programming may reduce fatigue while maintaining accuracy and dexterity. For more routine parts of the surgery, the surgeon may select a template and use the template interface to set various parameters for a given surgery, such as the force to be applied, order of tasks, trajectory of movement, stop points, and/or distance of any given movement in automatic operation for surgeon verification. By automating parts of the surgery, the surgeon may use direct control for more sensitive aspects of the surgery while having a respite or assistance for more routine aspects of the surgery.

Abstract: The invention provides a tip that permits therapeutic electromagnetic energy systems to deliver multiple beams of overlapping, partially overlapping, and non-overlapping electromagnetic energy in the treatment of tissue disorders and conditions. The tip finds use with laser systems, intense pulsed light systems, LED systems, radiofrequency systems, and microwave systems.

Abstract: Provided here are new ophthalmologically suitable pharmaceutical compositions comprising an effective amount of a moxifloxacin compound and an effective amount of a triamcinolone compound in suspension, wherein the particles of the suspension are limited in size. In aspects, the compositions are stable suspensions, maintaining physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, the compositions include a suspension component comprising one or more suspension agents. In aspects, the suspension component includes an ionic suspension agent. In aspects, the composition also or alternatively comprises a non-ionic surfactant, non-ionic suspension agent, or both, or an agent providing both functions. In aspects, such compositions further comprise an effective amount of a chelating agent/component.

Abstract: A planning device generating control data for a treatment apparatus for refraction-correcting ophthalmic surgery is provided, said apparatus using a laser device to separate a corneal volume, which is to be removed for correction, from the surrounding cornea by at least one cut surface in the cornea of an eye, said planning device comprising an interface for receiving corneal data including information on pre-operative cuts which were generated in a previous ophthalmic operation, and computing means for defining a corneal cut surface which confines the corneal volume to be removed, said computing means defining the corneal cut surface on the basis of the corneal data and generating a control dataset for the corneal cut surface for control of the laser device.

Abstract: Provided here are new ophthalmologically suitable pharmaceutical compositions comprising an effective amount of a moxifloxacin compound and an effective amount of a triamcinolone compound and a suspension component comprising a polysorbate, hyaluronic acid, or both. In aspects, the compositions are stable suspensions maintaining physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, the compositions comprise a non-ionic surfactant or, e.g., a non-ionic suspension agent providing both surfactant and suspension functionality. In aspects, such compositions further comprise an effective amount of a chelating agent/component. Further described are related compositions and methods of making and using such compositions, e.g., in the treatment of eye infections.

Abstract: Provided here are new ophthalmologically suitable pharmaceutical compositions comprising an effective amount of a moxifloxacin compound and an effective amount of a triamcinolone compound. In aspects, the compositions are stable suspensions, which maintain physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, the compositions are suspensions that include a suspension component comprising one or more suspension agents. In aspects, the suspension component includes an ionic suspension agent. In aspects, the composition also or alternatively comprises a non-ionic surfactant, non-ionic suspension agent, or both, or an agent that provides both functions. Further described are related compositions and methods of making and using such compositions, e.g., in the treatment of eye infections.

Abstract: An automated laser-surgery system for performing a closed-loop surgical procedure is disclosed. The procedure includes forming a post-procedural goal based on a three-dimensional (3D) image of a surgical site, planning a path for a surgical laser signal based on the post-procedural goal, performing a procedural pass by steering the surgical laser signal along the path, measuring the surface of the surgical site after the procedural pass, updating a model based on the measured effect at the surgical site, and evaluating the success of the procedural pass based on the surface measurement and the post-procedural goal. If necessary, a new path is planned based on the post-procedural goal and the surface measurement a new pass based on that path is performed, and the surface is again measured to evaluate the success of the new pass. These operations are repeated as a closed-loop sequence as many times as necessary to achieve success.

Abstract: A contact assembly (301,400) for laser surgery may include a contact lens (402) and an optical filter (404). The contact lens (402) may be configured to be positioned in an optical path of therapeutic radiation (310) directed at an eye (100) of a patient. The optical filter (404) may be coupled to an outer surface (402A) of the contact lens (402). The optical filter (404) may be transparent to the therapeutic radiation (310) with a first wavelength and may be opaque to radiation (318) with a second wavelength different than the first wavelength.

Abstract: A photomedical system and method for treating and/or diagnosing a patient's eye that includes a first light source for producing light, a scanning device for deflecting the light to produce a pattern of the light on the eye, a viewing element positioned to view the eye by a user or physician, and an alignment element aligned to the viewing element and the scanning device for optically indicating through the viewing element a location on the eye on which the pattern of the light will be located, but without projecting any alignment light onto the eye.

Abstract: Provided here are new ophthalmologically suitable pharmaceutical compositions comprising an effective amount of a moxifloxacin compound and an effective amount of a loteprednol compound. In aspects, the compositions are stable suspensions, which maintain physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, the compositions are suspensions that include a suspension component comprising one or more suspension agents. In aspects, the suspension component includes an ionic suspension agent. In aspects, the composition also or alternatively comprises a non-ionic surfactant, non-ionic suspension agent, or both, or an agent that provides both functions. In aspects, such compositions further comprise an effective amount of a chelating agent/component. Further described are related compositions and methods of making and using such compositions, e.g.

Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or ocular tissues is performed to address various types of vision correction.

Abstract: In some embodiments, a system for providing a therapeutic treatment to a patient's eye includes a treatment beam source configured to transmit a treatment beam along a treatment beam path. The system further includes a processor coupled to the treatment beam source, the processor being configured to direct the treatment beam onto retinal tissue of the patient's eye and deliver a series of short duration pulses from the treatment beam onto the retinal tissue at a first treatment spot to treat the retinal tissue. In some embodiments, a pre-treatment evaluation method using electroretinography (ERG) data may be used to predict effects of treatment beams at different power values and to determine optimal power values.

Abstract: Provided here are new ophthalmologically suitable pharmaceutical compositions comprising an effective amount of a moxifloxacin compound and an effective amount of a triamcinolone compound. In aspects, the compositions are stable suspensions, which maintain physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, the compositions are suspensions that include a suspension component comprising one or more suspension agents. In aspects, the suspension component includes an ionic suspension agent. In aspects, the composition also or alternatively comprises a non-ionic surfactant, non-ionic suspension agent, or both, or an agent that provides both functions. In aspects, such compositions further comprise an effective amount of a chelating agent/component. Further described are related compositions and methods of making and using such compositions, e.g.

Abstract: A device and a method for producing control data, which are designed to control a laser machining device to surgically correct ametropia of an eye in which, in order to define a space in the cornea, defines a front cutting surface, a rear cutting surface and an edge section, which are to be produced as cutting surfaces in the cornea. The rear cutting surface has a non-circular, oval edge lying in a plane, the edge section connecting the edge to the front cutting surface and the edge section being designed as a non-rotationally symmetrical cylinder or truncated cone, the base of which is the edge.

Abstract: An ophthalmic laser system for generating a first beam at a first wavelength on a first beam path and a second beam at a second wavelength on a second beam path, and directing optics to selectively direct the first wavelength or the second wavelength to a treatment beam path. The ophthalmic laser system a reflex coaxial illuminator comprising a reflex mirror movable on an from a axis a position out of the treatment beam path to a position in the treatment beam path to direct illumination into an illumination path coaxial with the treatment beam path and a safety interlock only allowing operation of the ophthalmic laser system on the first beam path if the reflex coaxial illuminator is in a first position and allowing operation of the ophthalmic laser system on either the first beam path or the second beam path if the reflex coaxial illuminator is not in the first position.

Abstract: Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in the subject's eye.

Abstract: A therapeutic method can include receiving an initial astigmatism condition of an eye; receiving a target final astigmatism condition of the eye; generating, based on the initial and target final astigmatism conditions, an eye incision pattern by iterating through a plurality of potential corrective combinations; and cutting the eye based on the eye incision pattern. Each of the potential corrective combinations can be defined by one or more of: an intraocular lens selected from a plurality of intraocular lens options, an access incision selected from a plurality of access incision options, and an arcuate incision selected from a plurality of arcuate incision options.

Abstract: Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye 1. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided.

Abstract: Systems, methods, and computer-readable media for integrating and optimizing a surgical suite. An ophthalmic suite can include a surgical console, a heads-up display communicatively coupled with a surgical camera for capturing a three-dimensional image of an eye, and a surgical suite optimization engine. The surgical suite optimization engine can performs a wide variety of actions in response to action codes received from the other components in the surgical suite. The surgical suite optimization engine can be integrated within another component of the surgical suite, can be a stand-alone module, and can be a cloud-based tool.

Abstract: An additive manufacturing system uses a trained artificial intelligence module as part of a closed-loop control structure for adjusting the initial set of build parameters in-process to improve part quality. The closed-loop control structure includes a slow control loop taking into account in-process build layer images, and may include fast control loop taking into account melt pool monitoring data. The artificial intelligence module is trained using outputs from a plurality of convolutional neural networks (CNNs) tasked with evaluating build layer images captured in-process and images of finished parts captured post-process. The post process images may include two-dimensional images of sectioned finished parts and three-dimensional CAT scan images of finished parts.

Abstract: A method for generating control data to control a laser device for correcting defective vision. A cut surface is specified which is curved, has a vertex and an edge, and is to be created in the eye. One or more paths, along which a focus of the laser radiation is to be adjusted, are defined for the control data and are selected such that they lie on or near the cut surface. To select the paths, a reference plane, preferably perpendicular, with respect to a direction of incidence of the laser radiation is determined, and different displacement positions are determined for said reference plane from the vertex to the edge of the cut surface. Multiple axes or semi-axes are determined for each displacement position. Intersections of the axes are connected into closed curves which are concentric or form a spiral.

Abstract: The invention relates to a method for forming curved cuts in a transparent material, in particular in the cornea, by the creation of optical perforations in said material using laser radiation that is focused in the material. The focal point is displaced three-dimensionally to form the cut by lining up the optical perforations. The focal point is displaced in a first spatial direction by a displaceable lens and said focal directions, in such a way that it follows the contours of the cut, which lie on a plane that is substantially perpendicular to the first spatial direction.

Abstract: A treatment device for the surgical correction of defective vision in an eye. The device includes a laser apparatus controlled by a controller. The controller determines a desired correction of defective vision from measurement data of the eye to produce control data for the laser, and to control the laser to emit radiation according to the control data, such that a lenticule-shaped volume is isolated in the cornea. The controller computes a lenticule-shaped intended volume, the removal of which from the cornea leads to an actual correction of defective vision in an optical zone in the eye which differs from the desired correction more at the edge of the optical zone than at the center of the optical zone. The thickness of the lenticule-shaped intended volume is less than the thickness of a lenticule-shaped comparison volume, the removal of which would bring about the desired correction of defective vision.

Abstract: An ophthalmic laser procedure for forming a lenticule in a cornea and extracting the lenticule from the cornea to accomplish vision correction. An ophthalmic laser system is used to form top and bottom lenticule incisions defining a lenticule in between, and further to form top and/or bottom entry cuts that respectively end unambiguously near the top or bottom lenticule surface. The bottom entry cut intersects both the top and bottom lenticule incisions but ends near the bottom lenticule incision. The entry cuts allow the surgeon to insert a surgical tool which reaches the intended top or bottom lenticule surface without ambiguity. The lenticule has an optical zone in the center that defines the optical power of the lenticule, and a transition zone in the periphery, where the end points of the entry cuts are located in the transition zone.

Abstract: Embodiments of this invention generally relate to systems and methods for optical treatment and more particularly to non-invasive refractive treatment method based on sub wavelength particle implantation. In an embodiment, a method for optical treatment identifies an optical aberration of an eye, determines a dopant delivery device configuration in response to the optical aberration of the eye, wherein the determined dopant delivery device is configured to impose a desired correction to the eye to mitigate the identified optical aberration of the eye by applying a doping pattern to the eye so as to locally change a refractive index of the eye.

Abstract: A light based system for treating an eye includes a mask that is configured for positioning on the eye and a light source that is configured to deliver therapeutic light. The mask has an inner surface that is positionable against the eye and an outer surface that is opposite the inner surface. The mask is optically opaque to prevent transmission of light through the mask and the mask includes at least one transparent opening that allows transmission of light through the mask to target tissue of the eye posterior the transparent opening. The light source is positioned relative to the mask so that the delivered therapeutic light irradiates at least a portion of the mask and the transparent opening. Therapeutic light traverses through the transparent opening to the target tissue positioned posterior the transparent opening.

Abstract: Embodiments of the present disclosure provide an endoscope apparatus and a method for controlling the endoscope apparatus. The endoscope apparatus may comprise an image collector, configured to collect an image for an eyeball of a user; a controller, configured to calculate a parameter for adjusting an endoscope lens of an endoscope based on the collected image; and the endoscope, configured to adjust the endoscope lens according to the parameter.

Abstract: A laser marking system for marking a predetermined pattern on a workpiece may include a first light source structured to emit first light at a first wavelength; a second light source structured to emit second light at a second wavelength different from the first wavelength and selected to mark a marking surface of the workpiece; beam shaping optics structured to adjust a focal length of the second light; beam steering optics structured to aim the first laser light and the second laser light; a controller configured to control the first light source to emit the first light at the marking surface of the workpiece and control the beam steering optics to aim the second light so as to mark the marking surface of the workpiece and create the first predetermined pattern; and a camera structured to detect first light reflected from the marking surface and record an image.

Abstract: Apparatus to treat an eye with an ophthalmic laser system comprises a patient interface having an annular retention structure to couple to an anterior surface of the eye. The retention structure is coupled to a suction line to couple the retention structure to the eye with suction. Liquid is added above the eye to act as a transmissive medium. A coupling sensor is coupled to the suction line to determine coupling of the retention structure to the eye. A separate pressure monitoring circuit having a much smaller volume than the suction line is connected to the annular retention structure to measure suction pressure therein. A system processor coupled to the monitoring pressure sensor includes instructions to interrupt firing of a laser when the pressure measured with a monitoring pressure sensor rises above a threshold amount.

Abstract: A system for therapy of the eye by treating tissue with therapeutic radiation using nonlinear interaction. A laser device is provided, which delivers the therapeutic radiation. The therapeutic radiation is focussed by a focussing device in an image field, and xy scanners and z scanners shift the focus laterally and longitudinally within a treatment volume. The therapeutic radiation is either a second short pulse radiation or a first short pulse radiation, each of which have a spectral centroid within a wavelength range defined by the short pulse properties. The system is particularly corrected with regard to longitudinal chromatic aberrations and lateral chromatic aberrations such that the spectral characteristic curves of the two aberrations each have a local extreme within the wavelength ranges, and a certain tolerance within the wavelength ranges is not exceeded, therefore the characteristic curves are very shallow.

Abstract: [Object] To provide an image processing device, an image processing method, and an image processing program that make it possible to perform an appropriate operation according to a procedure. [Solving Means] An image processing device according to the present technology includes: an image recognition section that performs an image recognition with respect to a front image that is a captured image of an eye; a display information generator that generates display information; and a controller that controls at least one of a cross-sectional information acquisition section or the display information generator according to a selected procedure, the cross-sectional information acquisition section acquiring cross-sectional information regarding a cross section of an eye.

Abstract: The present disclosure provides a system for femtosecond ophthalmic surgery in which the position of a suction cone in the z direction is measured via the measuring device to generate data that is processed and used to create a pictorial representation, a histogram, or other graph based on the data. The pictorial representation may include at least one threshold marker. The disclosure further provides a method of performing docking in femtosecond laser ophthalmic surgery including measuring the position of a suction cone with a measuring device, and transmitting data regarding the position to a processor which processes the data and uses it to create a pictorial representation, histogram, or other graph that is presented on a display.

Abstract: In a method for generating an ablation program for ablation of material from a surface of a body according to a predetermined desired ablation profile by emission of pulses of a pulsed laser beam onto the surface, the ablation program is generated from the desired ablation profile as a function of the shape of a beam profile of the laser beam and of an inclination of the surface to be ablated and/or considering a water content of the material to be ablated.

Abstract: A control apparatus for a phacoemulsification system is disclosed. The control apparatus is configured to supply electrical energy to an actuator for a phaco needle during a plurality of time intervals, wherein the time intervals includes a first time interval, in which electrical energy for pulses with a constant maximum amplitude is supplied, a second time interval following the first time interval, wherein electrical energy with a value equal to zero is supplied, and a third time interval following the second time interval, wherein the third time interval has a first time duration in which electrical energy for pulses which have a lower constant amplitude than the maximum amplitude during the first time interval is supplied.

Abstract: Methods and systems for producing a refractive prescription for a consumer away from an optical office are disclosed. At a first time point, a first prescription for a first pair of corrective lenses is generated according to measured refractive errors, and a historical visual acuity profile is measured using the first prescription and a varying spherical power. At a second time point, a second visual acuity is measured using the first prescription. A new spherical power is computed using the historical visual acuity profile and the second visual acuity. A second prescription for a second pair of corrective lenses is generated based on the first prescription and the new spherical power. In some embodiments, the second visual acuity may be self-administered by the consumer away from an optical office.

Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.

Abstract: A device for isolating a lenticle in the cornea of an eye. The device includes: a laser beam source to emit pulsed laser radiation having a pulse frequency of 1.2 MHz to 10 MHz, a pulse energy of 1 nJ to 200 nJ and a wavelength penetrating the cornea; a beam-forming unit having beam optics with an image field and that bundles pulsed laser radiation into a focus located inside the image field, and which has a maximum diameter of less than 3 ?m; a beam-deflection unit shifting the focus in the cornea and inside the image field, the focus moving along a path when the image field is resting; and a control unit to control the source and the beam-forming unit to isolate the lenticle by specifying the path. The lenticle is delimited by a cut surface which is curved with regard to a front surface of the cornea.

Abstract: A method for determining spherical aberration parameters for a corneal laser treatment to treat presbyopia may include performing pupillometry to measure various actual pupil diameters of a patient from a photopic diameter to a mesopic diameter. An actual pupil center of the patient may also be measured. The measured pupil diameters and the pupil center may be used to customize the spherical aberration parameters to the eye of the patient for improved ocular results after treatment.

Abstract: As shown in the drawings for purposes of illustration, a method and system for making physical modifications to intraocular targets is disclosed. In varying embodiments, the method and system disclosed herein provide many advantages over the current standard of care. Specifically, linear absorption facilitated photodecomposition and linear absorption facilitated plasma generation to modify intraocular tissues and synthetic intraocular lenses.

Abstract: Systems and methods for corneal laser ablation for primary vision correction include topographic guided ablation. A laser ablation pattern is derived at least in part from corneal topographic data and epithelial thickness data. The laser ablation pattern may limit post-surgical non-uniformity of the thickness of the epithelial layer.

Abstract: For the purposes of working on eye tissue, an opthalmological apparatus comprises a laser source that is configured to produce a pulsed laser beam, a focusing optical unit that is configured to focus the pulsed laser beam into the eye tissue, and a scanner system for deflecting the pulsed laser beam onto work target points in the eye tissue. A circuit controls the scanner system in such a way that the scanner system guides the pulsed laser beam into work trajectories that extend next to one another, in order, initially, to produce cut trajectories, separated by remaining tissue bridges, of a tissue cut to be undertaken in an area and in order, thereafter, to guide the pulsed laser beam in the remaining tissue bridges between the cut trajectories in order to complete the tissue cut.

Abstract: Systems and methods for corneal laser ablation for primary vision correction include topographic guided ablation. A laser ablation pattern for removal of astigmatism is derived at least in part from corneal topographic data rather than manifest astigmatism. Laser ablation patterns for treatment of high order aberrations of the cornea may also be based on corneal topographic data. Spherical corrections may be based on manifest refraction, eye models, or wavefront aberrometry.

Abstract: An eye implant with an optical implant region for correcting an imaging error of the eye. Biometrically determined data of optically effective components located in front of the retina of the eye is obtained through wave front measurement. The optical implant region is adjusted, based on the biometrically determined data, for a monofocal vision with a visual acuity of at least 0.7 (70%) within a field of focus depth of at least 2 diopters.

Abstract: The present invention relates to a virtual ray tracing method and dynamic light field refocusing display system, ray information collection, or random retrieval for pixels on a full focus image, so as to reduce ray collection total; and/or simplifying cross point retrieval where an object surface is regarded smooth. The system includes a virtual reality content processor, a virtual reality monitor, an eyeball tracker, an eyeball tracing processor, and a ray refocusing processor. The present invention reduces computational complexity, enables automatic replacement of erroneous sampling, causes to achieve real and accurate refocusing. The present invention may enable dynamic refocusing along a gazing direction of the human eye, and enable focusing by a user to objects of variable distance, to be consistent with viewing characteristics of the human eye.

Abstract: Described refractive correctors, include, but are not limited to, intraocular lenses (IOLs), contact lenses, corneal inlays, and other optical components or devices, incorporating a continuous central phase zone and peripheral phase discontinuities. Further embodiments are directed to a method for using a laser to modify the refractive properties of refractive correctors to form such continuous central phase zone and peripheral phase discontinuities, and other applications. The refractive corrector and methods adapt a Fresnel lens structure to include continuous phase retarding regions having a wavefront height of greater than one design wavelength in a central zone of a refractive corrector to improve human vision applications, while maintaining benefits of phase wrapping in the peripheral region.

Abstract: A patient adapter for an eye laser apparatus comprises a first partial adapter unit, including a suction ring portion to be placed on an eye and affixed on the eye by means of suction force, the suction ring portion having a ring axis; and a second partial adapter unit formed separately from the first partial adapter unit, the second partial adapter unit being configured for releasable coupling to the eye laser apparatus and including an eye contact element for shaping the surface of the eye, wherein the two partial adapter units are held together mechanically in a module between a first relative position, in which the eye contact element has a first axial position with respect to the suction ring portion, and a second relative position, in which the eye contact element has a second axial position with respect to the suction ring portion.

Abstract: A crosslinking control system, the use of the crosslinking control system, a laser system comprising the crosslinking control system, a crosslinking control method and a method for laser treatment are provided. The crosslinking control system comprises a photosensitizer providing unit, a light source configured to provide light having a wavelength suitable to activate the photosensitizer introduced into or applied onto the tissue for crosslinking, and a control computer.