Spinal Cord Patents (Class 607/117)
  • Patent number: 10814131
    Abstract: Apparatuses (e.g., devices, systems), and methods for transdermal electrical stimulation (TES). Apparatuses described herein can be self-contained, lightweight, and wearable. The apparatuses and methods described herein be configured to apply an ensemble current waveform between the two or more electrodes, wherein the ensemble current waveform comprises a series of component waveforms that are sequentially applied, and wherein each component waveform is different from a component waveform immediately before it and wherein transitions between the component waveforms temporally correlates with transitions in the sensory experience. Also described are neurostimulators for application of transdermal electrical stimulation (TES) and methods of using them for comfortably inducing a cognitive effect. Also described are Methods and apparatuses for amplitude modulation of all or a portion of an ensemble waveform to modify a user's cognitive state by transdermal electrical stimulation (TES).
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: October 27, 2020
    Assignee: Thync Global, Inc.
    Inventors: Isy Goldwasser, William J. Tyler, Jonathan Charlesworth, Sumon K. Pal, Daniel Z. Wetmore, Douglas Jeffery, Wing Law, Jason Egnal, Anil Thakur, Remi Demers, Jay Frederick Hamlin, Rafal Piersiak
  • Patent number: 10786671
    Abstract: A spinal cord stimulator device, including an implantation paddle, a connection segment and an encapsulant. The implantation paddle includes at least one pair of electrode stimulation pads, each of the electrode stimulation pads connected to ends of separate thin film electrode leads, wherein the electrode stimulation pads and the thin film electrode leads are sandwiched between softening polymer layers. The connection segment includes insulated wire leads, one end of each of the wire leads can be connected to contact pads on opposite ends of each one of the thin film leads at separated coupling joints. The encapsulant encompasses portions of the implantation paddle, including encompassing portions of the softening polymer layers surrounding the contact pads, the coupling joints and portions of the connection segment including portions of the wire leads next to the coupling joints. Methods of manufacturing device and using the device for spinal cord stimulation are also described.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: September 29, 2020
    Assignees: Board of Regents, The University of Texas System, Cornell University
    Inventors: Walter E. Voit, Aldo Garcia-Sandoval, Jason Carmel
  • Patent number: 10786672
    Abstract: Systems and methods for managing pain in a patient using an electrical waveform that link the modulation of a waveform parameter for different areas of a patient. One embodiment in a system for managing pain in a patient comprises an electric device configured to be implanted into the patient and including a plurality of electrodes having at least a first electrode associated with a first area of the patient and a second electrode associated with a second area of the patient. The system further includes an implantable device configured to be coupled to the electrode device and having a computer-operable medium programmed to change the waveform parameter applied to the first electrode and automatically set the waveform parameter applied to the second electrode based on a relationship between a first therapy range and a second therapy range of the waveform parameter.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: September 29, 2020
    Assignee: Nevro Corp.
    Inventors: Andre B. Walker, Jon Parker
  • Patent number: 10780272
    Abstract: The present invention is a fitting system with a graphical interface with specific interface screens for specific functions. Methods and devices for fitting a visual prosthesis are described. In one of the methods, threshold levels and maximum levels for the electrodes of the prosthesis are determined and a map of brightness to electrode stimulation levels is later formed. A fitting system for a visual prosthesis is also discussed, together with a computer-operated system having a graphical user interface showing visual prosthesis diagnostic screens and visual prosthesis configuration screens.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: September 22, 2020
    Assignees: Second Sight Medical Products, Inc., Doheny Eye Institute
    Inventors: Matthew J. McMahon, Arup Roy, Scott Greenwald, Ione Fine, Alan Matthew Horsager, Avraham I. Caspi, Kelly Hobart McClure, Robert Jay Greenberg
  • Patent number: 10716932
    Abstract: Improved stimulation circuitry for controlling the stimulation delivered by an implantable stimulator is disclosed. The stimulation circuitry includes memory circuitry that stores pulse programs that define pulse shapes, steering programs that define electrode configurations, and aggregate programs that link a selected pulse program with a selected steering program. Each steering program defines the stimulation polarity and the allocation of current of the specified stimulation polarity for each of the pulse generator's electrodes. Each pulse program includes one or more pulse instructions, where each instruction defines the parameters of a single phase of the pulse program. Pulse definition circuits in the stimulation circuitry execute aggregate programs to generate stimulation waveforms, which stimulation waveforms can be generated simultaneously by the different pulse definition circuits.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: July 21, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Philip Leonard Weiss, Goran N. Marnfeldt, David Michael Wagenbach
  • Patent number: 10702696
    Abstract: Delivering stimulation includes delivering temporal patterns of stimulation pulses to respective transducers of an array of transducers, wherein the delivery of the pattern to a particular transducer of the array is different from at least some of the deliveries of the patterns to the other transducers of the array at least according to a time delay. The patterns delivered may include regular temporal patterns each having a respective constant inter-pulse interval. The constant inter-pulse intervals may be about the same. The patterns may be staggered. The transducers may deliver electrical, optical, acoustic, thermal or magnetic stimulation.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: July 7, 2020
    Assignee: Duke University
    Inventors: Warren M. Grill, Tianhe Zhang
  • Patent number: 10688302
    Abstract: Embodiments of the present invention relate to methods for applying epidural electrical stimulation to improve motor function or physiological responses in paralyzed individuals. More particularly, the present invention relates to methods for creating and applying specific configurations of epidural stimulation to assist or cause a patient to perform a complex motor function or to mitigate one or more secondary consequences of paralysis including, but not limited to, cardiovascular, respiratory, bladder, temperature and sexual dysfunction.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: June 23, 2020
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Susan J. Harkema, Yangshen Chen, Manikandan Ravi, Claudia Angeli, Charles Hubscher
  • Patent number: 10682516
    Abstract: Methods for identifying responders to paresthesia-free stimulation therapy, and associated systems are disclosed. A representative method comprises implanting a pair of spinal cord signal delivery devices and connecting an external signal generator thereto. A plurality of the electrical contacts are simultaneously activated with a high frequency signal without causing paresthesia in the patient, wherein the electrical contacts would cause paresthesia in the patient if activated with a low frequency signal. The high frequency signal is in a range of from about 3 kHz to about 20 kHz and an amplitude of less than 4 mA. If the patient responds favorably, a signal generator is implanted in the patient. A second high frequency signal is then applied to fewer than the plurality of electrical contacts.
    Type: Grant
    Filed: February 17, 2018
    Date of Patent: June 16, 2020
    Assignee: Nevro Corp.
    Inventors: James R. Thacker, Andre B. Walker, Jon Parker, Bradford Evan Gliner, Heinz Moeri
  • Patent number: 10668285
    Abstract: It has been discovered that pain felt in a given region of the body can be treated, not by motor point stimulation of muscle in the local region where pain is felt, but by stimulating muscle spaced from a “nerve of passage” in a region that is superior (i.e., cranial or upstream toward the spinal column) to the region where pain is felt. Spinal nerves such as the intercostal nerves or nerves passing through a nerve plexus, which comprise trunks that divide by divisions and/or cords into branches, comprise “nerves of passage.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: June 2, 2020
    Assignee: SPR THERAPEUTICS, INC.
    Inventor: Joseph W. Boggs, II
  • Patent number: 10639476
    Abstract: An electronic stimulation device is adapted for electrically stimulating a target zone of an organism. The electronic stimulation device comprises at least one electronic stimulation unit. The electronic stimulation unit includes at least one first electrode and at least one second electrode. The electronic stimulation unit receives an electrical stimulation signal to impel the first electrode and the second electrode to generate an electric field. The range of the electric field covers the target zone, and the electric field strength ranges from 100 V/m to 1000 V/m. The electronic stimulation unit comprises a plurality of subunits and each subunit comprises at least one first electrode and at least one second electrode. An electronic stimulation system and the manufacturing method thereof are also provided.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: May 5, 2020
    Assignee: GIMER MEDICAL CO., LTD.
    Inventors: Chi-Heng Chang, Mei-Ching Wang
  • Patent number: 10610690
    Abstract: A fully implantable trial neurostimulation system for implant within a patient is provided that includes one or more leads equipped to deliver neurostimulation to patient tissues under the control of a trial neurostimulation control device designed as a capsule for removable implant within the patient. The control capsule is provided with minimal components to power and control the delivery of neurostimulation during a trial evaluation period and is shaped and configured to facilitate removal from the patient following completion of the trial period. In some examples, both the lead and the trial control capsule are removed from the patient following the trial period for replacement with a chronic or long-term neurostimulation system (assuming further neurostimulation is warranted.) In other examples, the lead remains within the patient and the trial control capsule is replaced with a long-term neurostimulation controller device. Various minimally-intrusive implantation procedures are also described.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: April 7, 2020
    Assignee: Pacesetter, Inc.
    Inventors: Yelena Nabutovsky, Melanie Goodman Keiser, Gene A. Bornzin
  • Patent number: 10610682
    Abstract: An electrode for use with a cochlear implant system includes an electrode array with electrode contacts distributed along the electrode array, and an electrode lead adjacent to the electrode array. The electrode lead has (1) a flexible region configured to allow the electrode lead to bend, (2) an attachment mechanism with an internal portion positioned within and along a longitudinal direction of the electrode lead, and an external portion configured to be bent and secured to bone, the external portion having an attachment element configured to secure the attachment mechanism to the bone, and (3) a securing element extending from the electrode lead and located further back from the flexible region toward a rear end of the electrode lead, the securing element configured to secure the electrode lead to the bone. A method of securing the electrode to bone is also disclosed.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: April 7, 2020
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventors: Claude Jolly, Anandhan Dhanasingh
  • Patent number: 10583291
    Abstract: An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body has a programmable signal generator that can generate the signals based on stored signal parameters without any intervention from a processor that controls the overall operation of the IPG. While the signal generator is generating the signals the processor can be in a standby mode to substantially save battery power.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: March 10, 2020
    Assignee: Cirtec Medical Corp.
    Inventors: Christopher Biele, Raghavendra Angara, Saif Khalil
  • Patent number: 10569091
    Abstract: Methods and devices are provided for, under control of one or more processors within an implantable medical device (IMD), delivering cardiac resynchronization therapy (CRT) at one or more pacing sites. The processors obtain cardiac signals, associated with a candidate beat, from multi-site left ventricular (MSLV) electrodes distributed along a left ventricle and analyze the cardiac signals to collect at least one of a MSLV conduction pattern or a MSLV morphology. The processors compare at least one of the MSLV conduction pattern or MSLV morphology to one or more associated templates. The processors then label the candidate beat as a pseudo-fusion beat based on the comparing and adjust the CRT based on the labeling.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: February 25, 2020
    Assignee: PACESETTER, INC.
    Inventors: Nima Badie, Jan Mangual-Soto, Luke McSpadden, Aditya Goil
  • Patent number: 10537740
    Abstract: A method and external control device for providing therapy to a patient using first and second electrodes implanted within the patient is provided. A train of electrical multi-phasic pulses is generated. A first electrical current is sourced from the second electrode and at least a portion of the first electrical current is sunk to the first electrode during a stimulation phase of each multi-phasic pulse, thereby therapeutically stimulating a first tissue region adjacent the first electrode. A second electrical current is sourced from the first electrode and at least a portion of the second electrical current is sunk to the second electrode during a charge recovery phase of each multi-phasic pulse, thereby recovering at least a portion of the charge that had been injected into the patient during the stimulation phase of each multi-phasic pulse, and therapeutically stimulating a second tissue region adjacent the second electrode.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: January 21, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Rafael Carbunaru, Kerry Bradley
  • Patent number: 10493277
    Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 kHz to about 100 kHz may be applied to the patient's spinal cord region to address abdominal pain without creating paresthesia in the patient.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: December 3, 2019
    Assignee: Nevro Corp.
    Inventors: James R. Thacker, Konstantinos Alataris, Bradford Evan Gliner
  • Patent number: 10456576
    Abstract: Devices, systems and methods for reducing migration of leads, catheters and similar devices are provided. In particular, devices, systems and methods are provided for creating a slack anchor which assists in maintaining the lead or catheter in a desired position. In some embodiments, the slack anchor is created within the epidural space. When targeting nerve anatomy within the spinal column or in the vicinity of the epidural space, anchoring within the epidural space allows the associated lead or catheter to be anchored as close to the target therapy site as desired or possible. By anchoring close to the target therapy site, the risk of movement or migration is significantly reduced or eliminated.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: October 29, 2019
    Inventors: Eric J. Grigsby, Daniel M. Brounstein, Fred I. Linker
  • Patent number: 10434313
    Abstract: We disclose multi-electrode, energy-recycling, resonant stimulation circuits and strategies for energy-efficient blocking of action potentials in nerve. Our schemes increase the probability that most of the electrical stimulation is directed through the nerve rather than dissipated in ohmic extracellular solution alongside it via mechanical and electrical means; they use energy-recycling and resonant-amplification strategies that recycle and amplify capacitive nerve energy such that the nerve itself becomes an integral part of the circuit creating its oscillatory blocking waveform; they use traveling-wave strategies with distributed multi-electrode stimulation that alters the timing and intensity of stimulation at various points along the nerve to synchronize blocking stimulation with wave propagation in the nerve in an energy-efficient fashion.
    Type: Grant
    Filed: November 28, 2015
    Date of Patent: October 8, 2019
    Assignee: Rahnix, Inc.
    Inventors: Rahul Sarpeshkar, Woradorn Wattanapanitch
  • Patent number: 10420948
    Abstract: An implantable medical device (“IMD”) as described herein includes an adjustable data retransmission scheme, which controls the manner in which data is retransmitted by the IMD. The retransmission feature can be adjusted in a dynamic manner based upon the type, context, or meaning of the telemetry data transmitted by the IMD. The IMD may process contextual meaning information that influences its data retransmission configuration. Such adjustability enables the IMD to satisfy minimum telemetry requirements in a manner that does not waste power, thus extending the IMD battery life.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: September 24, 2019
    Assignee: Medtronic, Inc.
    Inventors: Javaid Masoud, Charles H. Dudding, Robert A. Patrias
  • Patent number: 10413736
    Abstract: The disclosure is directed to an implant tool and cannula used to facilitate the implantation of a medical device into a patient. The implant tool includes a housing that is held by a user and a needle attached to the housing. The cannula may be positioned over the needle and delivered to a target tissue within the patient. The cannula includes an electrode at a distal portion to deliver test stimulation to confirm the location of the target site or placement of the implant tool relative to the target site before removing the needle of the implant tool. In this manner, the cannula may be repositioned within the patient until the position of the implant tool and cannula relative to the target site is verified with the test stimulation.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: September 17, 2019
    Assignee: Medtronic, Inc.
    Inventors: Eric H. Bonde, Martin T. Gerber
  • Patent number: 10391304
    Abstract: An implantable electrical lead is provided. The electrical lead comprises an electrically insulative, flexible, elongated lead body having a proximal end and a distal end, an electrical contact carried by the distal end of the lead body, an electrical terminal carried by the proximal end of the lead body, an electrical conductor axially extending within the lead body between the electrical contact and the electrical terminal, and a stiffening tube extending within the proximal end of the lead body from a point proximal to the terminal to a point distal to the terminal and proximal to the electrode. An implantable lead assembly kit comprises the implantable electrical lead, and a connector configured for firmly receiving the proximal end of the lead body. A method of implanting the electrical lead comprises introducing the electrical lead into a patient.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: August 27, 2019
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Matthew Braden Flowers, John Michael Barker
  • Patent number: 10384058
    Abstract: An apparatus for securing a sensor at the heart is formed based on a modified, branched, pacemaker lead to provide a heart anchor lead where two anchors are coupled to a single main lead rather than there being just a single anchor. Thus, the proposed heart anchor lead comprises a single main lead, a sensor included within the main lead, in which the sensor has a distal end and a proximal end, a first anchor coupled to the distal end of the sensor and extending outward from the distal end of the sensor, and a second anchor coupled to the proximal end of the sensor and extending outward from the proximal end of the sensor in a direction that forms an angle with the first anchor. The heart anchor lead can optionally also have a pacemaking function.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: August 20, 2019
    Assignee: Cardiaccs AS
    Inventors: Erik Fosse, Jonas Tyssø
  • Patent number: 10383657
    Abstract: One aspect of the present disclosure relates to a cannula for passing a tissue graft through soft tissue. The cannula can comprise an elongated body including oppositely disposed first and second ends and an axis that extends between the first and second ends. The elongated body can further include a passage extending between the first and second ends. The second end can include a curved portion that terminates at a sharpened, pointed tip configured to pierce and/or cut soft tissue at the surgical repair site. The tip can be axially offset from the axis of the elongated body at an angle that is less than 180°.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: August 20, 2019
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Kathleen A. Derwin, Joseph P. Iannotti, Ryan A. Milks
  • Patent number: 10368761
    Abstract: An implanted neural micro interface device is provided. The device comprises microfilaments of various materials and forms embedded within a body. The microfilaments form interaction sites with surrounding neural tissue at their exit points from the implantable body. The body and filaments are configurable in a multitude of positions to provide increased engagement of a given neural tissue section as well as interaction and closed loop feedback between the microfilament sites. Such configurations allow for a range of recording, stimulating, and treatment modalities for the device within research and clinical settings.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: August 6, 2019
    Assignee: Modular Bionics Inc.
    Inventors: Ian Loren Halpern, Mark William Merlo
  • Patent number: 10342128
    Abstract: Thicker electrodes are provided on microelectronic device using thermo-compression bonding. A thin-film electrical conducting layer forms electrical conduits and bulk depositing provides an electrode layer on the thin-film electrical conducting layer. An insulating polymer layer encapsulates the electrically thin-film electrical conducting layer and the electrode layer. Some of the insulating layer is removed to expose the electrode layer.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: July 2, 2019
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Kedar G. Shah, Satinderpall S. Pannu, Vanessa Tolosa, Angela C. Tooker, Heeral J. Sheth, Sarah H. Felix, Terri L. Delima
  • Patent number: 10328271
    Abstract: In some examples, an implantable medical device includes an implantable housing, a neurostimulator within the housing, a plurality of electrodes, an implantable lead coupled to the housing, and an actuator formed with the housing. The implantable lead includes at least one electrode of the plurality of electrodes and one or more conductors coupling the at least one electrode to the neurostimulator. The actuator is configured to cause at least a portion of the implantable lead to deflect.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: June 25, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Eric H. Bonde, John E. Kast, Erik R. Scott, Xuan K. Wei
  • Patent number: 10328256
    Abstract: Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods. A method for treating a patient in accordance with a particular embodiment includes selecting a neural modulation site to include a neural population of the patient's spinal cord, and selecting parameters of a neural modulation signal to at least reduce an autonomic system deficit in the patient.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: June 25, 2019
    Assignee: Nevro Corp.
    Inventor: Bradford Evan Gliner
  • Patent number: 10292656
    Abstract: Methods of fabricating ultra-miniature, ultra-compliant probe arrays through spin coating, wherein a dissolvable material in hydrogel form is dispensed onto an assembled mold with wires. Once the dissolvable material is dispensed onto the mold, centrifuging spin casts the material by evaporating the solvent, forming a dried dissolvable polymer. Finally, a device is used with water to remove excess dissolvable material to obtain a dissolvable needle with wires.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: May 21, 2019
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Gary K. Fedder, Burak Ozdoganlar, Peter J. Gilgunn
  • Patent number: 10286216
    Abstract: The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a three-dimensional (3D) stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates the 3D stimulation field in a 3D environment to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to the 3D anatomical regions of the patient.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: May 14, 2019
    Assignee: Medtronic, Inc.
    Inventors: Richard T. Stone, Warren W. Ball, Carl D. Wahlstrand, Steven M. Goetz, Lynn M. Otten
  • Patent number: 10271899
    Abstract: A device, method, and system for adding mapping functionality to an ablation device without adding electrodes, wiring, or other components to the ablation device. The device includes a treatment catheter including a proximal portion and a distal portion, the distal portion including a longitudinal groove. The device also includes a mapping catheter including a proximal portion and a distal portion, the distal portion of the mapping catheter being coupled to the distal portion of the treatment catheter. For example, the distal portion of the mapping catheter is snapped into the groove of the treatment catheter. Together the treatment and mapping catheters are transitionable between a variety of configurations. In this way, the medical device may be used to both treat and map tissue without complicating the design and manufacture of the treatment catheter.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: April 30, 2019
    Assignee: Medtronic Cryocath LP
    Inventor: Ioana Deac
  • Patent number: 10252065
    Abstract: The present disclosure relates to a pulse generating system comprising a pulse generator for generating a pulse or pulses and a controller for controlling the pulse generating means, where the pulse generating system is capable to work in at least a regular mode and a safety mode, where in the regular mode the pulse generator and the controller are connected and where in the safety mode there is no connection between the pulse generator and the controller and where in the safety mode the pulse generator automatically switches to a baseline stimulation command.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: April 9, 2019
    Assignee: GTX medical B.V.
    Inventors: Vincent Delattre, Joachim Von Zitzewitz, Sjaak Deckers
  • Patent number: 10245427
    Abstract: A neurostimulation system is disclosed herein. The neurostimulation system includes an implantable pulse generator and an implantable therapy lead configured to be electrically coupled to the implantable pulse generator. The implantable therapy lead includes a flexible paddle electrode array with flexible electrodes. Each flexible electrode has a segmented configuration having first and second electrode segments and a flexible bridge or living hinge joining together the first and second electrode segments.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: April 2, 2019
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Jodi Townsley Dubuclet
  • Patent number: 10238865
    Abstract: An implantable medical device assembly includes a mounting structure, an electrode protruding from a surface of the structure, between opposing sides thereof, and tissue-penetrating fixation tines, each extending from a corresponding shoulder of the structure surface, adjacent to the opposing sides. In a relaxed condition, each tine extends away from the surface and then bends toward a proximal end of the structure and back toward the surface. In an extended condition, each tine bends toward a distal end of the structure and extends along the corresponding shoulder. A holding member of a delivery tool has opposing sidewalls defining a cavity, wherein each sidewall includes a rail-like edge that fits in sliding engagement with a corresponding shoulder, to deform a corresponding tine into the extended condition, when an operator passes the assembly into the cavity. Applying a push force, to move the assembly back out form the cavity, releases the tines.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: March 26, 2019
    Assignee: Medtronic, Inc.
    Inventors: Matthew D Bonner, Raymond W Usher, Teresa A Whitman, Jean M Carver, Kathryn Hilpisch
  • Patent number: 10220210
    Abstract: Systems and methods for managing pain in a patient using an electrical waveform that link the modulation of a waveform parameter for different areas of a patient. One embodiment in a system for managing pain in a patient comprises an electric device configured to be implanted into the patient and including a plurality of electrodes having at least a first electrode associated with a first area of the patient and a second electrode associated with a second area of the patient. The system further includes an implantable device configured to be coupled to the electrode device and having a computer-operable medium programmed to change the waveform parameter applied to the first electrode and automatically set the waveform parameter applied to the second electrode based on a relationship between a first therapy range and a second therapy range of the waveform parameter.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: March 5, 2019
    Assignee: Nevro Corp.
    Inventors: Andre B. Walker, Jon Parker
  • Patent number: 10213148
    Abstract: A system and method for modeling patient-specific spinal cord stimulation (SCS) is disclosed. The system and method acquire impedance and evoked compound action potential (ECAP) signals from a lead positioned proximate to a spinal cord (SC). The lead includes at least one electrode. The system and method determine a patient-specific anatomical model based on the impedance and ECAP signals, and transform a dorsal column (DC) map template based on a DC boundary of the patient-specific anatomical model. Further, the system and method map the transformed DC map template to the patient-specific anatomical model. The system and method may also include the algorithms to solve extracellular and intracellular domain electrical fields and propagation along neurons. The system and method may also include the user interfaces to collect patient responses and compare with the patient-specific anatomical model as well as using the patient-specific anatomical model for guiding SCS programming.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: February 26, 2019
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Alexander Kent
  • Patent number: 10092750
    Abstract: Neuromodulation systems are described comprising a signal generator and at least one electrode. The at least one electrode can be configured to deliver a stimulation to a mammal, wherein the stimulation includes a biphasic signal and an overlapping high frequency pulse thereby inducing voluntary movement in the individual. Methods of administering the stimulation are also described.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: October 9, 2018
    Assignee: Neuroenabling Technologies, Inc.
    Inventors: Victor Reggie Edgerton, Yury P. Gerasimenko, Nicholas A. Terrafranca, Parag Gad
  • Patent number: 10076657
    Abstract: Various embodiments of this disclosure concern a lead end containing a slotted member. A slotted member can have a plurality of slots extending along at least a portion of the length of the slotted member, each of the slots having a respective positioning feature, the plurality of slots having a plurality of positioning features at different longitudinal positions along the length of the slotted member. The lead end can further include a plurality of conductors at least partially within the plurality of slots, each slot of the plurality of slots containing at least a respective one of the plurality of conductors, the plurality of conductors electrically connecting exposed electrical elements of both ends of the lead.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: September 18, 2018
    Assignee: MEDTRONIC, INC.
    Inventors: Daniel C. Oster, Rodney J. Haberte, Jeffrey M. Novotny
  • Patent number: 10065323
    Abstract: A robotic actuator includes an internal anchor and an instrument. The internal anchor is adapted to be inserted into a body via an entrance port, positioned inside the body, and magnetically coupled with an external anchor positioned outside the body. The instrument is adapted to be inserted into the body via the entrance port and secured to the internal anchor. The instrument includes an end-effector having multiple degrees of movement via multiple axes, and a plurality of actuators that provide the multiple degrees of movement.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: September 4, 2018
    Assignee: Bio-Medical Engineering (HK) Limited
    Inventors: Chung Kwong Yeung, Kai Leung Yung
  • Patent number: 9913975
    Abstract: A neurostimulation system and method of providing therapy to a patient implanted with a plurality of electrodes using a plurality of electrical sources is provided. A source-electrode coupling configuration is determined from the electrical sources and electrodes. Electrical current is respectively conveyed between active ones of the plurality of electrical sources and active subsets of the plurality of electrodes in accordance with the determined source-electrode coupling configuration. The total number of the electrodes in the active electrode subsets is greater than the total number of the active electrical sources.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: March 13, 2018
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Rafael Carbunaru, Kristen Jaax, Andrew DiGiore
  • Patent number: 9907966
    Abstract: An electrical stimulation system provides stimulation therapy to a patient. The system includes a neurostimulation lead that contacts patient tissue and couples with an implantable stimulation device, such as an implantable pulse generator, that receives stimulation parameters for providing stimulation therapy to a patient. The implantable stimulation device includes a header with a plurality of connector assemblies that receive an end of the neurostimulation lead, and a case containing a charging coil and a telemetry coil coupled to programming circuitry on a printed circuit board, which is in turn coupled to the connector assemblies via a feedthrough assembly. The telemetry coil receives data from an external programmer and transmits the data to the programming circuitry, which in turn uses the data to communicate to the connector assemblies and the neurostimulation lead to provide stimulation therapy to a patient.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: March 6, 2018
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Jeffery V. Funderburk, Randy L. Brase, Robert R. Tong, Md. Mizanur Rahman
  • Patent number: 9901732
    Abstract: The present disclosure may comprise an improvement to the prior art leads as disclosed above. One embodiment is directed to an intravenous medical electrical lead that includes an elongated lead body. The elongated lead body comprises a length between proximal and distal ends with a longitudinal axis extending therebetween. The distal end of the lead body includes a plurality of electrodes forming first and second pairs of electrodes. The first pair of electrodes comprises one electrode electrically connected to another electrode circumferentially and diagonally spaced apart along the longitudinal axis. The second pair of electrodes comprising one electrode electrically connected to another electrode circumferentially and diagonally spaced apart along the longitudinal axis.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: February 27, 2018
    Assignee: Medtronic, Inc.
    Inventors: John L Sommer, William J Clemens, Linda L Franke
  • Patent number: 9901737
    Abstract: A method for providing therapy to a patient using intermittent electrical stimulation includes advancing a plurality of electrodes disposed along a distal portion of a lead to a target stimulation location within a patient. A proximal portion of the lead is coupled to an electrical stimulator disposed external to the patient. Patient tissue at the target stimulation location is stimulated for a first duration of time that is no greater than one day using the plurality of electrodes. The stimulation provides efficacious treatment to the patient for a second duration of time that is at least twice as long as the first duration of time. Stimulation is ceased after completion of the first duration of time. The lead is removed from the patient after ceasing stimulation and prior to an end of the second duration of time.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: February 27, 2018
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Michael A. Moffitt, Stephen Carcieri
  • Patent number: 9833611
    Abstract: An electrical stimulation lead or lead extension includes a body having an outer surface, a proximal end, a proximal portion, at least one distal portion, an outer surface, a perimeter, and a longitudinal length, the body defining an alignment slit extending distally from the proximal end of the body and splitting the proximal portion of the body into two transversely space-apart sections; first contacts disposed along the distal portion of the body; segmented second contacts disposed along the proximal portion of the body, where each segmented second contact extends around less than the entire perimeter of the body and is separated from all other segmented second contacts by portions of the body or the alignment slit; and conductors electrically coupling the first contacts to the second contacts.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: December 5, 2017
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Michael X. Govea, Joshua Dale Howard
  • Patent number: 9827423
    Abstract: Systems and methods for managing pain in a patient using an electrical waveform that link the modulation of a waveform parameter for different areas of a patient. One embodiment in a system for managing pain in a patient comprises an electric device configured to be implanted into the patient and including a plurality of electrodes having at least a first electrode associated with a first area of the patient and a second electrode associated with a second area of the patient. The system further includes an implantable device configured to be coupled to the electrode device and having a computer-operable medium programmed to change the waveform parameter applied to the first electrode and automatically set the waveform parameter applied to the second electrode based on a relationship between a first therapy range and a second therapy range of the waveform parameter.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: November 28, 2017
    Assignee: Nevro Corp.
    Inventors: Andre B. Walker, Jon Parker
  • Patent number: 9820811
    Abstract: Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: November 21, 2017
    Assignee: SYMAP MEDICAL (SUZHOU), LTD
    Inventor: Jie Wang
  • Patent number: 9814488
    Abstract: A surgical probe and a method for forming and enlarging an access opening through a psoas muscle to provide for minimally invasive lateral approach for surgical access to a lumber intervertebral disc. A distal end portion of the probe is equipped with an electrode useful for confirming proper location of the probe and includes an inflatable dilator body for enlarging an access opening through tissue adjacent to a spinal column. The probe includes a cannula through which a K wire can be extended to anchor the probe to a patient.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: November 14, 2017
    Assignee: GLOBUS MEDICAL, INC.
    Inventor: Robert Louis Tatsumi
  • Patent number: 9808614
    Abstract: An implantable curved shaping part for externally shaping an implantable electrode line or a catheter, wherein the shaping part has a continuous first lumen to allow a portion of the electrode line or of the catheter to pass through, wherein the shaping part has an extruded tube formed from two materials, each coextruded over a predetermined wall segment, having different shrinkage behavior or has a portion of an extruded spiral tube, wherein one of the coextruded materials or the material of the spiral tube has a high Shore hardness, in particular, of 60 Shore or more.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: November 7, 2017
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Detmar Jadwizak, Carsten Fruendt, Dajana Kaiser, Gordon Hillebrand
  • Patent number: 9802038
    Abstract: Anchoring devices and methods for affixing an implanted lead of a neurostimulation system at a target location in a patient are provided herein. Such anchoring devices includes a helical body having a plurality of tines extending laterally outward from the lead when deployed that engage tissue to inhibit axial movement of the implanted lead. The plurality of tines are biased towards the laterally extended deployed configuration and fold inward towards the lead to a delivery configuration to facilitate delivery of the lead through a sheath. The tines may be angled in a proximal direction or in both proximal and distal directions and may include various features to assist in visualization and delivery of the lead. The anchor may be formed according to various methods, including laser cutting of a tubular section along with heat or reflow to set the material with the anchor in the deployed configuration and injection molding.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: October 31, 2017
    Assignee: AXONICS MODULATION TECHNOLOGIES, INC.
    Inventors: Henry Lee, Alexander Hwu
  • Patent number: 9782580
    Abstract: A percutaneously implantable paddle lead includes an elongated lead body having a proximal portion and a distal portion; a plurality of terminals disposed on the proximal portion of the lead; a flexible paddle body coupled to the distal portion of the lead; and a plurality of electrodes disposed in the paddle body and electrically coupled to the terminals on the proximal portion of the lead. The percutaneously implantable paddle lead also includes a bonding material in contact with the paddle body and holding the paddle body in a compacted form prior to, and during, insertion into a percutaneous implantation tool. The bonding material is configured and arranged to release the paddle body during or soon after implantation into a patient so that the paddle body can deploy into its paddle-like form. Alternatively, at least one current-degradable fastener can be used instead of the binding material.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: October 10, 2017
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Anne Margaret Pianca, Douglas Michael Ackermann
  • Patent number: 9776011
    Abstract: An implantable curved shaping part for externally shaping an implantable electrode line or a catheter, wherein the shaping part has a continuous first lumen to allow a portion of the electrode line or of the catheter to pass through, wherein the shaping part is formed as an injection molded part or has at least one injection molded portion, and an elongated, rigid yet flexible bend impression element is fixed within the wall or to the inner wall.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: October 3, 2017
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Detmar Jadwizak, Carsten Fruendt, Dajana Kaiser, Gordon Hillebrand