Abstract: A medical device includes an implantable device having a processor, a pulse generator and a first lead having first and second ends. The first end of the lead is operably and conductively coupled to the implantable device. A first electrode is operably and conductively coupled to the second end of the first lead. The first electrode has a sharp tip for transmitting and focusing a stimulation signal from the pulse generator to a tissue site.

Abstract: An implantable lead includes a lead body. A plurality of conductors are disposed within the lead body and electrically couple at least one electrode to at least one terminal. At least one of the conductors includes a plurality of units. Each of the units includes a first conductor segment extending along the lead body from a beginning point to a first position, a second conductor segment extending from the first position to a second position, and a third conductor segment extending along the elongated member from the second position to an endpoint. The conductor segments are arranged so as to form alternating single-coil regions and multi-coil regions. At least one support element is disposed along at least a portion of at least one of the single-coil regions and is configured and arranged to increase the stiffness of the at least one of the single-coil regions.

Abstract: The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a three-dimensional (3D) stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates the 3D stimulation field in a 3D environment to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to the 3D anatomical regions of the patient.

Abstract: The present invention relates to a multi-column paddle structure and its uses thereof to provide neuromodulation therapy to a patient.

Abstract: A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

Abstract: The present disclosure describes various embodiments of an insertion tool that affords steerability of the paddle-style electrode during implantation without causing damage to the insulation and/or the contacts of the paddle-style electrode. One embodiment is described as having a “pin fork” configuration; another a “shovel” configuration; and yet another has tabs or a lumen on the paddle-style electrode for facilitating the insertion of a stylet. The various embodiments for the insertion tool allow for adjustments of the paddle-style electrode in both the medial/lateral and inferior/superior directions allowing the surgeon to steer the paddle-style electrode to the desired stimulation site within the epidural space of the spinal column.

Abstract: Couplings for implanted leads and external stimulators, and associated systems and methods are disclosed. A system in accordance with a particular embodiment includes a cable assembly that in turn includes an electrical cable having a proximal end and a distal end. A first connector is attached to the cable toward the proximal end and has a plurality of first connector contacts positioned to releasably connect to an external patient device. A second connector is attached by the cable toward the distal end, and includes a first portion and a second portion pivotably connected to the first portion. The first portion has a slot elongated along a slot axis and positioned to receive an implantable patient signal delivery element axially along the slot axis.

Abstract: System and methods for channeling a path into bone include a trocar having a proximal end, distal end and a central channel disposed along a central axis of the trocar. The trocar includes a radial opening at or near the distal end of the trocar. The system includes a curveable cannula sized to be received in the central channel, the curveable cannula comprising a curveable distal end configured to be extended laterally outward from the radial opening in a curved path extending away from the trocar. The curveable cannula has a central passageway having a diameter configured to allow a probe to be delivered through the central passageway to a location beyond the curved path.

Abstract: In one embodiment, an implantable neurostimulator comprises a pulse generator that generates an electrical pulse signal to stimulate a neural structure in a patient, a stimulation lead assembly coupled to the pulse generator for delivering the electrical pulse signal to the neural structure, a plurality of sensors coupled to the pulse generator, and sensor select logic. Each sensor is individually selectable and the sensor select logic selects any two or more of the plurality of sensors for sensing a voltage difference between the selected sensors. In other embodiments, two or more physiologic parameters are sensed. In yet another embodiment, a method comprises sensing intrinsic electrical activity on a person's nerve and stimulating the nerve based on the sensed intrinsic electrical activity of the nerve.

Abstract: An electrode has a unitary ring with an exterior surface, an interior surface, and at least two edges. The electrode also includes a seat formed in at least the exterior surface of the unitary ring. The seat is configured and arranged for attachment of a terminal end of a lead wire, disposed in the seat, to the electrode. A lead includes a lead body; a plurality of electrodes disposed at the distal end of the lead body; and a plurality of lead wires. Each electrode includes a unitary ring and a seat in the unitary ring. The unitary ring has an exterior surface and an interior surface and defines a hollow center region. The seat is formed as a depression of a portion of the unitary ring. Each of the lead wires extends along the lead body and is attached to a corresponding electrode at the seat of the corresponding electrode.

Abstract: A method for implanting an electrical stimulation lead into a patient includes advancing a distal end of a multi-armed lead into an epidural space of the patient. The multi-armed lead includes first and second stimulation arms extending from a main body portion. The first stimulation arm is guided into and through a first intervertebral foramen. The first stimulation arm is positioned in proximity to a first dorsal root ganglion. The first stimulation arm is positioned with electrodes disposed along the first stimulation arm in operational proximity to the first dorsal root ganglion. The second stimulation arm is guided into and through a second intervertebral foramen. The second stimulation arm is positioned in proximity to a second dorsal root ganglion. The second stimulation arm is positioned with electrodes disposed along the second stimulation arm in operational proximity to the second dorsal root ganglion.

Abstract: An implantable lead assembly for providing electrical stimulation to a patient includes a lead body; a terminal disposed along a proximal end of the lead body; and an orthopedic implant coupled to a distal end of the lead body. The orthopedic implant is configured and arranged for anchoring to a bony structure. At least one mounting region is disposed along the orthopedic implant. The at least one mounting region is configured and arranged for anchoring the orthopedic implant to the at least one bony structure. An electrode is disposed along a stimulation region of the orthopedic implant. A conductor electrically couples the terminal to the electrode.

Abstract: A device for stimulating body tissue includes a lead body and at least one stimulating electrode disposed on the lead body. The lead body is configured and arranged to be substantially rigid outside the patient's body and during insertion into the patient's body and then becomes non-rigid upon exposure within the patient's body.

Abstract: A method for modulating nerve tissue in a body of a patient includes implanting a wireless stimulation device in proximity to a dorsal root ganglion or an exiting nerve root such that an electrode, circuitry and a receiving antenna are positioned completely within the body of the patient. An input signal containing electrical energy and waveform parameters is transmitted to the receiving antenna(s) from a control device located outside of the patient's body via radiative coupling. The circuitry within the stimulation device generates one or more electrical impulses and applies the electrical impulses to the dorsal root ganglion or the exiting nerve roots through the electrode.

Abstract: An implantable electrode array assembly configured to apply electrical stimulation to the spinal cord. A substantially electrically nonconductive layer of the device has a first portion positionable alongside the spinal cord that includes a plurality of first openings. The layer has a second portion that includes a plurality of second openings. Electrodes and traces are positioned inside a peripheral portion of a body portion of the device and alongside the layer. At least one of the first openings is adjacent each of the electrodes to provide a pathway through which the electrode may provide electrical stimulation to the spinal cord. At least one of the second openings is adjacent each of the traces to provide a pathway through which the trace may receive electrical stimulation. At least one trace is connected to each electrode and configured to conduct electrical stimulation received by the trace(s) to the electrode.

Abstract: An MRI compatible electrode circuit construct is provided. The construct includes at least two filter components constructed from an electrode wire. One filter component may be a resonant LC filter at or near an electrode/wire interface that resolves the issue of insufficient attenuation by effectively blocking the RF induced current on the wire from exiting the wire through the electrode. The second filter component may include one or more non-resonant filter(s) positioned along the length of the electrode wire that resolve(s) the issue of excessive heating of the resonant LC filter by significantly attenuating the current induced on the wire before it reaches the resonant LC filter. The non-resonant filter(s) may also attenuate the RF current reflected from the resonant LC filter thereby resolving the issue of the strong reflected power from the resonant filter and the associated dielectric heating.

Abstract: An MRI compatible electrode circuit construct is provided. The construct includes at least two filter components constructed from an electrode wire. One filter component may be a resonant LC filter at or near an electrode/wire interface that resolves the issue of insufficient attenuation by effectively blocking the RF induced current on the wire from exiting the wire through the electrode. The second filter component may include one or more non-resonant filter(s) positioned along the length of the electrode wire that resolve(s) the issue of excessive heating of the resonant LC filter by significantly attenuating the current induced on the wire before it reaches the resonant LC filter. The non-resonant filter(s) may also attenuate the RF current reflected from the resonant LC filter thereby resolving the issue of the strong reflected power from the resonant filter and the associated dielectric heating.

Abstract: Disclosed herein is a method of assembling an implantable medical lead configured to receive a stylet. The lead is provided with a tubular insulation layer, an electrode is disposed on the tubular insulation layer, an electrical conductor is routed through the tubular insulation layer, and a stylet stop is inserted into a distal end of the tubular insulation layer. The electrical conductor is directly and mechanically connected to the stylet stop and is in electrical communication with the electrode.

Abstract: A hopper having a passage through which a medicine can be passed downward is provided. A part of a lower portion of the hopper is a deformable portion having flexibility, and the deformable portion is deformable so as to open and close the passage. According to this configuration, the deformable portion that is a part of the hopper is deformed to open and close the passage. Thus, there is no portion such as an opening and closing plate on which the medicine remains, thereby preventing a gap in which the medicine remains from being formed in the hopper, and preventing the medicine from easily remaining in the hopper.

Abstract: Implantation tools for spinal cord stimulator leads and related methods are disclosed. According to an aspect, an implantation tool may include an elongated body having first and second ends. The elongated body may define an interior extending between the first and second ends. The first end may be configured for connection to a vacuum pump for drawing air through the interior in a direction generally from the second end towards the first end. The second end may define an opening for engaging a lead of the spinal cord stimulator when air is drawn by the vacuum pump.

Abstract: A lead, method of manufacturing same, and system for stimulation is provided. The lead includes an insulative member or layer that masks a portion of the electrode(s) to effectively generate a directional lead that focuses or directs the stimulation to desired location(s). In another embodiment, the lead further includes a marking system to allow a clinician to orient the directional lead, as desired, while the lead is within a body.

Abstract: An electrode assembly includes one or more electrode contact surfaces, and a cuff, to which the contact surfaces are fixed, and which comprises an electrically insulating material, is configured to assume open and closed positions, and, when in the closed position, is shaped so as to define a plurality of planar cross sections perpendicular to a longitudinal axis of the cuff, distributed continuously along an entire length of the cuff along the longitudinal axis, such that the perpendicular cross sections define respective inner closed curves that together define an inner surface that defines and completely surrounds a volume that extends along the entire length of the cuff. The inner closed curves of at least two of the perpendicular cross sections would cross, and not merely intersect, one another if superimposed while preserving orientation and position of the perpendicular cross sections with respect to the cuff. Other embodiments are also described.

Abstract: Methods and devices for stimulating the spinal cord are provided. The method involves positioning an electrical lead in the intrathecal space adjacent to the desired level of the spinal cord. Electrical leads are provides that help stabilize the lead in the intrathecal space and provide for focal stimulation of the spinal cord.

Abstract: Systems, devices and methods to anchor the distal portion of an implantable electrical lead using a coupling system to prevent or minimize lead migration. Magnetic-assisted anchoring systems are disclosed.

Abstract: Electrical lead positioning systems, devices, and methods are disclosed. Systems include an implantation tool having a malleable portion to allow a user to customize the configuration of the implantation tool to navigate to the target site of a patient's body. Electrical leads are also provided with retention features to secure the implantation tool to the lead during use.

Abstract: The present invention provides systems, devices and methods for positioning a lead at a target site in a patient's body. Electrical lead positioning systems include positioning devices that aid in positioning electrodes of an electrical lead closer to the therapy site.

Abstract: A system that includes an anchor assembly, the anchor assembly including: at least one anchoring structure configured to be anchored in a head of a patient; and at least one lead anchoring structure; and b. at least one lead, the at least one lead including a lead body extending from a distal end to a proximal end; at least one electrode located on or in the distal end of the lead body; and at least one lead anchor located on or in the lead body proximal to the electrode, wherein the at least one lead anchor of the lead and the lead anchoring structure are configured to cooperate to secure the at least one lead to the anchor assembly.

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

Abstract: An implantable lead having at least one electrode contact at or near its distal end prevents undesirable movement of the electrode contact from its initial implant location. One embodiment relates to a spinal cord stimulation (SCS) lead. A first injectable material is injected into the dura space to mechanically position the electrode array with respect to the spinal cord. Conjunctively for use with adhesives, or alternatively for use instead of the adhesives, a balloon may be positioned on the electrode lead array. The balloon is filled with air, liquid or a compliant material. When inflated, the balloon stabilizes the lead with respect to the spinal cord and holds the lead in place. An elastic aspect of the balloon serves as an internal contained relief valve to limit the pressure the balloon may place on the surrounding tissues when the epidural space is constrained.

Abstract: Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region from an epidural, cervical location to address at least one of high back pain, mid-back pain, low back pain, and leg pain without creating paresthesia in the patient.

Abstract: Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region from an epidural, cervical location to address at least one of high back pain, mid-back pain, low back pain, and leg pain without creating paresthesia in the patient.

Abstract: A device for brain stimulation includes a cannula configured and arranged for insertion into a brain of a patient; at least one cannula electrode disposed on the cannula; and an electrode lead for insertion into the cannula, the electrode lead comprising at least one stimulating electrode.

Abstract: A lead connection system includes a connector housing. A plurality of lead retainers disposed in the connector housing are configured and arranged to removably attach to a proximal end of one of a received plurality of leads. The plurality of lead retainers include at least one of a slidable drawer and at least one pivotable hinged panel. A plurality of connector contacts are configured and arranged for making electrical contact with one or more of the terminals of one or more of the plurality of received leads. A single connector cable has a distal end that is electrically coupled to the plurality of connector contacts and a proximal end that is configured and arranged for insertion into a trial stimulator. A cable connector is electrically coupled, via the connector contacts, to at least one terminal of each of the received plurality of leads.

Abstract: A therapy delivery element adapted to be implanted into a living body. The therapy delivery element includes an electrode portion with a plurality of electrodes. At least one elongated lead body is attached to the electrode portion. The elongated lead body includes a stylet coil having a stylet coil lumen. The stylet coil extends within the elongated lead body and along at least a portion of the electrode portion. A conductor assembly with a plurality of insulated electrical conductors is braided to extending around the stylet coil and to electrically couple to one or more of the electrodes. The conductor assembly includes an inner lumen with a diameter greater than an outside diameter of the stylet coil. Axial elongation of the elongated lead body reduces the inner diameter of the conductor assembly. A low durometer insulator extends around the conductor assembly.

Abstract: An implantable electrical lead comprising an elongate lead body comprising first and second ends and an outer housing defining an interior channel. At least one electrical contact is positioned along the elongate lead body. An anchoring system is disposed at one end of the elongate lead body. The anchoring system is movable between an elongate configuration and a compressed configuration. The compressed configuration has a greater diameter than the elongate configuration. A linkage is provided having a first end attached to the anchoring system, an intermediate portion disposed within the interior channel of the elongate lead body, and a second end disposed outside of the elongate lead body adjacent to the second end of the elongate lead body. Movement of the linkage away from the elongate lead body moves the anchoring system from the elongate configuration to the compressed configuration.

Abstract: A neurostimulation comprises a plurality of electrical terminals configured for being respectively coupled to an array of electrodes, at least three configurable sources respectively coupled to at least three of the electrical terminals, and control circuitry configured for programming each of the at least three configurable sources to be either a current source or a voltage source. A method of providing neurostimulation therapy to a patient using an array of electrodes implanted adjacent neural tissue of the patient, comprises conveying electrical stimulation energy between a first one the electrodes and a second one of the electrodes, thereby creating an electrical field potential within the neural tissue, regulating a first current flowing through the first electrode, and regulating a first voltage at a third different one of the electrodes, thereby modifying a shape of the electrical field potential within the neural tissue.

Abstract: A programming-device user interface may include multiple levels of abstraction for programming treatment settings. A stimulation zone-programming interface may be at a highest level of abstraction and may include idealized stimulation zones. A field strength-programming interface may be at a middle level of abstraction and may include electromagnetic field-strength patterns generated by the stimulation zones, and/or electrode settings, and a depiction of how the electromagnetic fields interact with each other. An electrode-programming interface may be at a lowest level of abstraction and may depict treatment settings at an electrodes-view level. These interfaces may include a display of a stimulatable area of the patient's body. The display may include a depiction of leads and/or the underlying physiology, such as a depiction of a portion of a spine. Algorithms map treatment settings from one level of abstraction to settings at one or more other levels of abstraction.

Abstract: In one embodiment, a neurostimulation lead comprises an elongated body of insulative material, comprising a first end portion and a second end portion; a plurality of terminals longitudinally positioned along the first end portion; a plurality of electrodes longitudinally positioned along the second end portion; a plurality of conductors electrically coupling the plurality of electrodes to the plurality of terminals; a flexible metal longitudinal stiffener positioned within the elongated body wherein the stiffener has a plurality of longitudinal zones and each zone has a different column strength, the column strength of one or more zones of the plurality of longitudinal zones being defined by cuts or gaps in the stiffener, the stiffener causing the neurostimulation lead to exhibit a greatest amount of column strength adjacent to one end portion of the elongated body and to transition to a lower column strength toward a medial portion of the elongated body.

Abstract: A method of inducing forced expiration in a subject is disclosed. The method can include percutaneously placing an injectable microstimulator adjacent at least one thoracic spinal nerve that innervates an intercostal muscle. For example, the microstimulator is placed within 8 cm externally of a neuroforamen through which the spinal nerve emerges from a thoracic vertebra. The method can also entail applying a stimulating electrical current from the microstimulator to the thoracic spinal nerve at a sufficient intensity and duration to induce a forced contraction of the intercostal muscle innervated by that spinal nerve.

Abstract: The present invention provides devices, systems and methods for anchoring medical devices to hard tissues, such as bones or bony structures, particularly vertebrae. By anchoring these medical devices directly to the surrounding hard tissue, the devices are anchored closer to the source of treatment. This provides additional stability and reduces migration of the device at the treatment site. Also, by attaching to hard tissue rather than soft tissue, a stronger attachment is often able to be made.

Abstract: A lead includes an elongated body and an anchor segment disposed between the distal end of the body and electrodes on a distal portion of the body. The anchor segment has lobes which are separated by slits and movable between a collapsed position and an expanded position. A positioning mechanism is disposed inside the hollow interior of the body and at least partially within the anchor segment. The positioning mechanism has a distal positioning portion attached to the distal end of the body and a proximal positioning portion. A control member is connected with the proximal positioning portion to control the positioning mechanism to pull the distal end toward the proximal end so as to move the lobes from the collapsed position to the expanded position and to push the distal end away from the proximal end so as to move the lobes from the expanded to the collapsed position.

Abstract: A neurostimulation paddle lead, method of neurostimulation, and neurostimulation system are provided. The neurostimulation paddle lead carries a plurality of electrodes comprising at least four columns of electrodes having a spacing between two inner electrode columns less than a spacing between the inner electrode columns and adjacent outer electrode columns. The inner electrode columns may also be longitudinally offset from the outer electrode columns. The methods and neurostimulation systems steer current between the electrodes to modify a medial-lateral electrical field created adjacent spinal cord tissue.

Abstract: An improved anchoring mechanism for an implantable lead is discussed. The anchoring mechanism consists of a tine enclosed in a housing structure. Deployment and retraction of the tine is controlled by the rotation of a stylet releasable connected to the tine. The stylet is inserted through the lead and engages the tine at an interface between them. The stylet is rotated. This serves to rotate the tine to thereby secure the lead connected to an anchor housing from which the tine emerges to body tissue.

Abstract: Multi-frequency neural treatments and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes at least reducing patient pain by applying a first electrical signal to a first target location of the patient's spinal cord region at a frequency in a first frequency range of up to about 1,500 Hz, and applying a second electrical signal to a second target location of the patient's spinal cord region at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz.

Abstract: An implantable medical lead includes a lead body having a proximal portion having a longitudinal axis and an arcuate distal body portion extending in the direction of the longitudinal axis. The arcuate distal body portion has a concave surface. The lead includes a plurality of elongate electrodes disposed at the arcuate distal end portion of the lead body along the concave surface. The electrodes extend substantially parallel to the longitudinal axis of the lead body.

Abstract: A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

Abstract: Bilumen catheters and methods of using same for facilitating implantation of cardiac leads for applying electrical stimulation to and/or sensing electrical activity of the heart through one or more electrode positioned at an implantation site within a heart chamber or cardiac vessel adjacent a heart chamber, and more particularly to a method and apparatus for introducing such a cardiac lead having low torqueability and pushability through a tortuous pathway to enable attachment of the cardiac lead at the implantation site employing a bilumen guide catheter are disclosed. The bilumen catheter body includes a relatively large diameter delivery lumen to introduce a small diameter cardiac lead and a small diameter guide lumen to receive a stylet or guidewire to locate the guide catheter body distal end at the implantation site. The small diameter lumen within a small diameter guide tube extends distally from the delivery exit port of the delivery lumen.

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

Abstract: A lead assembly comprises an outer body tubing, first and second conductors, and first and second tubing insert members. The outer body tubing comprises at least two longitudinal outer body tubing portions, each such portion comprising a through-hole and each portion comprising a keyed surface having a predetermined shape. Each of the tubing insert members receives a conductor and comprises a surface that substantially matches the predetermined shape of the keyed surface. When both of the conductors are inserted into corresponding longitudinal through-holes such that each of said first and second surfaces of the first and second hollow body members is substantially aligned with the keyed surface of a corresponding outer body tubing portion, electrodes formed on ends of the first and second conductors are encouraged to be substantially co-linear.

Abstract: In one embodiment, a method, of fabricating a stimulation lead for stimulating tissue of a patient, comprises: providing a lead body, the lead body comprising a plurality of conductors embedded within insulating material; providing a plurality of terminals; electrically coupling the plurality of terminals with the plurality of conductors; providing a plurality of electrodes, the plurality of electrodes comprising a plurality of substantially continuous longitudinal trenches on a surface of the electrodes, the electrodes comprising areas of reflow material forming microstructures substantially continuously along walls of the longitudinal trenches; and electrically coupling the plurality of electrodes with the plurality of conductors.