Measuring Pacing, Threshold, Capture Margin, Or Contact Impedance Patents (Class 607/28)
  • Patent number: 11413467
    Abstract: The disclosure describes various aspects of an automated external defibrillator (AED) system, including shock generating electronics, a battery configured for providing power to the shock generating electronics, power management circuitry configured for managing the shock generating electronics and the battery, at least one environmental sensor configured for monitoring environmental conditions in which the AED system is placed, and a controller configured for controlling the power management circuitry and the at least one environmental sensor. The at least one environmental sensor includes a temperature sensor configured for providing a temperature measurement, and the controller is further configured for adjusting operations of the power management circuitry in accordance with the temperature measurement provided by the temperature sensor. The disclosure further describes associated methods of using the AED system.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: August 16, 2022
    Assignee: HeartHero, Inc.
    Inventors: Clifford H. Wallach, Michael C. Garrett
  • Patent number: 11413463
    Abstract: A cardiac stimulation system and associated capture management method are provided in which capture and device longevity are improved. The device determines a series of capture thresholds. Capture threshold is the minimum pulse level (pulse energy or pulse amplitude or pulse width) that captures the heart. Each determination requires delivery of pacing pulses at several (at least two) known levels (pulse energy, pulse amplitude and/or pulse width) over time. The individual determined capture thresholds are combined into a set and the variability of the set is used to set the safety margin. The greater the variability in the capture thresholds, the bigger the safety margin.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: August 16, 2022
    Assignee: Medtronic, Inc.
    Inventors: Eric A. Shilling, Karen J. Kleckner
  • Patent number: 11400298
    Abstract: Techniques are disclosed for using a rate of wireless telemetry of an implantable medical device (IMD) to estimate a remaining longevity of a power source of the IMD. For example, the IMD sets a timer indicative of a remaining power capacity of the power source until a recommended replacement time (RRT) threshold. The IMD determines a power consumption of the IMD due to telemetry and updates, based on the power consumption of the IMD due to telemetry, the timer indicative of the remaining power capacity of the power source. The IMD determines, based on expiration of the timer indicative of the remaining power capacity of the power source, that the power source has reached the RRT threshold. In some examples, the IMD may output, to an external device and for display to a user, an indication that the power source has reached the RRT threshold.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: August 2, 2022
    Assignee: Medtronic, Inc.
    Inventors: Matthew J. Hoffman, Matthew P. Hanly, Evan S. Johnson, Gary J. Pauly, Jerry D. Reiland, Melani G. Sullivan, Ryan D. Wyszynski, Hyun J. Yoon
  • Patent number: 11400295
    Abstract: Systems and methods for His bundle pacing and classifying response to pacing impulses include applying, using a pulse generator, an impulse through a stimulating electrode to induce a response from a patient heart. A response to the impulse is measured using at least one sensing electrode and time-domain based characteristics of the response are analyzed to determine whether His bundle capture has occurred and, if so, what type of capture has occurred.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: August 2, 2022
    Assignee: Pacesetter, Inc.
    Inventors: Xiaoyi Min, Yun Qiao, Wenwen Li, Jan O. Mangual-Soto, Luke C. McSpadden
  • Patent number: 11351382
    Abstract: The disclosure describes an enhancement to lead monitoring techniques, which uses a sensing integrity counter (SIC). The techniques of this disclosure may enhance lead monitoring techniques by detecting possible sensing issues based on a significant increase in periodic, e.g., daily, SIC counts relative to previous periods. Some issues with sensing cardiac signals via implantable cardiac leads can result in an implantable medical device (IMD) measuring very short intervals between what appears to be sensed heart beats. Examples of issues include insulation breach, conductor fracture, or poor electrical connection, which may cause noise that appears to be an R-wave. The IMD may detect the noise, along with actual R-waves, and determine that there are relatively short (e.g., less than a threshold) intervals between the “R-waves.” A significant increase in the number or frequency of very short intervals between R-waves may indicate the date/time of a significant sensing issue.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: June 7, 2022
    Assignee: Medtronic, Inc.
    Inventor: Bruce D. Gunderson
  • Patent number: 11344236
    Abstract: A method of generating an electrophysiology map of a portion of a patient's anatomy using an electroanatomical mapping system, includes defining a plurality of inclusion criteria, collecting a plurality of electrophysiology data points, each being associated with inclusion data, and identifying those electrophysiology data points that have inclusion data satisfying the inclusion criteria. The inclusion criteria can then be automatically adjusted to drive the number of electrophysiology data points having inclusion data satisfying the inclusion criteria towards a target number. A graphical representation of the electrophysiology map can be rendered using the final set of electrophysiology data points.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: May 31, 2022
    Assignee: ST JUDE MEDICAL CARDIOLOGY DIVISION, INC.
    Inventors: Craig Markovitz, Louis-Philippe Richer, Chunlan Jiang, Cyrille Casset
  • Patent number: 11318298
    Abstract: An exemplary monitoring system 1) monitors evoked responses that occur in response to acoustic stimulation during an insertion procedure in which a lead that is communicatively coupled to a cochlear implant is inserted into a cochlea of a patient, the monitoring comprising using an intracochlear electrode disposed on the lead to measure a first and a second evoked response at a first and a second insertion depth within the cochlea, the second insertion depth nearer to an apex of the cochlea than the first insertion depth, 2) determines that a change between the first evoked response measured at the first insertion depth and the second evoked response measured at the second insertion depth is greater than a predetermined threshold, and 3) determines, based on the determination that the change is greater than the predetermined threshold, that cochlear trauma has likely occurred at the second insertion depth.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: May 3, 2022
    Assignee: Advanced Bionics AG
    Inventors: Kanthaiah Koka, Leonid M. Litvak
  • Patent number: 11311734
    Abstract: The present disclosure relates generally to pacing of cardiac tissue, and more particularly to adjusting delivery of His bundle or bundle branch pacing in a cardiac pacing system to achieve synchronized ventricular activation. A leadless pacing device (LPD) may include a plurality of electrodes comprising a bundle pacing electrode leadlessly connected to the housing, which may be implanted proximate to or in the His bundle or bundle branch of the patient's heart. An electrical pulse generator may generate and deliver electrical His-bundle or bundle-branch stimulation pulses using the bundle pacing electrode based on sensing one or both of an atrial event and a ventricular event. The LPD may receive communication from another implantable device, such as a subcutaneously implanted device, and deliver His-bundle or bundle-branch pacing in response to the communication.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: April 26, 2022
    Assignee: Medtronic, Inc.
    Inventor: Xiaohong Zhou
  • Patent number: 11305124
    Abstract: A medical device system and associated method predict a patient response to a cardiac therapy. The system includes for delivering cardiac pacing pulses to a patient's heart coupled to a cardiac sensing module and a cardiac pacing module for generating cardiac pacing pulses and controlling delivery of the pacing pulses at multiple pace parameter settings. An acoustical sensor obtains heart sound signals. A processor is enabled to receive the heart sound signals, derive a plurality of heart sound signal parameters from the heart sound signals, and determine a trend of each of the plurality of heart sound signal parameters with respect to the plurality of pace parameter settings. An external display is configured to present the trend of at least one heart sound parameter with respect to the plurality of pace parameter settings.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: April 19, 2022
    Assignee: Medtronic, Inc.
    Inventors: Xusheng Zhang, Jeffrey M. Gillberg, Thomas J. Mullen
  • Patent number: 11235161
    Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: February 1, 2022
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11239928
    Abstract: Described herein is an implantable medical device (IMD) that wirelessly communicates another IMD, and methods for use therewith. Such a method can include receiving one or more implant-to-implant (i2i) communication signals from the other IMD using a communication receiver of the IMD, measuring a strength of at least one of the one or more received i2i communication signals or a surrogate thereof, and updating a strength metric based on the measured strength or surrogate thereof. The method further includes determining, based on the updated strength metric, whether to increase, decrease, or maintain the sensitivity of the communication receiver of the IMD, and responding accordingly such that the sensitivity is sometimes increased, sometimes decreased, and sometimes maintained. The method can also include selectively causing a transmitter of the IMD to transmit an i2i communication signal to the other IMD requesting that the other IMD adjust its transmission strength.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: February 1, 2022
    Assignee: Pacesetter, Inc.
    Inventors: Matthew G. Fishler, Benjamin T. Persson, Suresh Gurunathan
  • Patent number: 11185701
    Abstract: An intracardiac ventricular pacemaker having a motion sensor, a pulse generator and a control circuit coupled to the pulse generator and the motion sensor is configured to identify a ventricular systolic event, detect a ventricular passive filling event signal from the motion signal, and determine a time interval from the ventricular systolic event to the ventricular passive filling event. The pacemaker establishes a minimum pacing interval based on the time interval.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: November 30, 2021
    Assignee: Medtronic, Inc.
    Inventors: Wade M. Demmer, Juliana E. Pronovici, Todd J. Sheldon
  • Patent number: 11160487
    Abstract: A method for analyzing a condition of a heart, comprises receiving a plurality of electric signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: November 2, 2021
    Assignee: AALBORG UNIVERSITET
    Inventors: Jacob Melgaard, Johannes Jan Struijk, Claus Graff
  • Patent number: 11077305
    Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: August 3, 2021
    Assignee: MEDTRONIC, INC.
    Inventors: Jonathon E. Giftakis, Timothy J. Denison, Paul H. Stypulkowski, Scott R. Stanslaski, Robert S. Raike, Mae Eng, David E. Linde, Thomas Adamski
  • Patent number: 11052255
    Abstract: Systems and methods for pacing cardiac conductive tissue are described. A medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses. A sensing circuit senses a physiologic signal, and detect a local His-bundle activation discrete from a pacing artifact of the HBP pulse. A control circuit verifies capture status in response to the HBP pulses. Based on the capture status, the control circuit determines one or more pacing thresholds including a selective HBP threshold representing a threshold strength to capture only the His bundle but not the local myocardium, and a non-selective HBP threshold representing a threshold strength to capture both the His bundle and the local myocardium. The electrostimulation circuit may deliver HBP pulses based on the selective and non-selective HBP thresholds.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: July 6, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Amy Jean Brisben, David J. Ternes, Allan Charles Shuros, Deepa Mahajan, David L. Perschbacher
  • Patent number: 11024404
    Abstract: A system and method for medical image based patient-specific ischemic stroke risk prediction is disclosed. Left atrium (LA) and left atrium appendage (LAA) measurements are extracted from medical image data of a patient. Derived metrics for the LA and LAA of the patient are computed using a patient-specific computational model of cardiac function based on the LA and LAA measurements extracted from the medical image data of the patient. A stroke risk score for the patient is calculated based on the extracted LA and LAA measurements and the computed derived metrics for the LA and LAA of the patient using a trained machine learning based classifier, which inputs the extracted LA and LAA measurements and the computed derived metrics for the LA and LAA as features.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: June 1, 2021
    Assignee: Siemens Healthcare GmbH
    Inventors: Viorel Mihalef, Puneet Sharma
  • Patent number: 10918876
    Abstract: Disclosed are systems, devices and methods that produce at least two distinct temporal components from two distinct endocardial electrogram (EGM) signals collected concurrently, determines a non-temporal 2D characteristic representative of the cardiac cycle to be analyzed, from the variations of one of the temporal components as a function of another of the temporal components and comparing the characteristic of the current cycle to two reference characteristics previously obtained and stored, one in a situation of complete capture and the other in a situation of spontaneous rhythm. Respective values of similarity descriptors are derived of these two comparisons, which are used to calculate a metric quantifying a fusion rate.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: February 16, 2021
    Assignee: Sorin CRM SAS
    Inventors: Paola Milpied, Delphine Feuerstein
  • Patent number: 10905349
    Abstract: A method for mapping atrial fibrillation (AF) in a heart, the method includes receiving an electrogram (EGM) signal, which is acquired at a given position in the heart, and is exhibiting the AF. Two or more primary peaks are identified in the EGM signal, and a cycle length (CL) is calculated between adjacent primary peaks. One or more secondary peaks are identified in the EGM signal within the CL. A local fragmentation index (FI) that is indicative of a number of the secondary peaks per CL, is calculated. The local FI is visualized on a map of at least part of the heart.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: February 2, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Ziyad Zeidan, Aharon Turgeman, Benjamin Cohen, Yaron Kadoshi
  • Patent number: 10799281
    Abstract: A medical device system may be configured to detect an improper energy transmission configuration therein. The condition may be detected by way of a detection of a condition where an energy-transmitting electrode of the medical device system becomes too close to or becomes in contact with an object resulting in an inability of the electrode to properly transmit energy. For example, if the energy-transmitting electrode is a first electrode configured in its operational state to transmit energy to bodily tissue adjacent the first electrode, but the first electrode is inadvertently contacting a second electrode, such contact may cause at least some energy transmitted by the first electrode to follow an unintended path away from its intended path to the adjacent tissue. Such a condition may be detected based at least upon an analysis of information acquired from a sensing device system.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: October 13, 2020
    Assignee: KARDIUM, INC.
    Inventors: Douglas Wayne Goertzen, Daniel Martin Reinders, Daniel Robert Weinkam
  • Patent number: 10596381
    Abstract: An implantable or other ambulatory medical apparatus comprises a posture sensing circuit, a physiologic sensing circuit that senses a time varying physiologic signal, and a processor circuit. The processor circuit includes a posture calculation circuit and a measurement circuit. The posture calculation circuit determines a posture of the subject using posture data obtained using the posture signal and determines when the posture of the subject is steady state. The measurement circuit derives a physiologic measurement using physiologic data extracted from the physiologic signal during at least one time period when posture is determined to be steady state and provides the physiologic measurement to at least one of a user and a process in association with the determined steady state posture.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: March 24, 2020
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Viktoria A. Averina, John D. Hatlestad, Abhilash Patangay, Pramodsingh Hirasingh Thakur, Yi Zhang, Kenneth C. Beck
  • Patent number: 10575346
    Abstract: A method, system and external instrument are provided. The method initiates a communication link between an external instrument (EI) and an implantable medical device (MD), established a first connection interval for conveying data packets between the EI and IMD and monitors a connection criteria that includes at least one of a data throughput requirement. A battery indicator or link condition of the communications link is between the IMD and EI. The method further changes from the first connection interval to a second connection interval based on the connection criteria.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: February 25, 2020
    Assignee: PACESETTER, INC.
    Inventors: Yongjian Wu, Chao-Wen Young, Jun Yang, Xing Pei, Reza Shahandeh
  • Patent number: 10561326
    Abstract: Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally (in the midline) on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow “hourglass”-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and, to a lesser extent, the QRS interval signals indicating ventricular activity in the ECG waveforms. Additionally, the monitor recorder includes an ECG sensing circuit that measures raw cutaneous electrical signals and performs signal processing prior to outputting the processed signals for sampling and storage.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: February 18, 2020
    Assignee: BARDY DIAGNOSTICS, INC.
    Inventors: Jason Felix, Jon Mikalson Bishay, Gust H. Bardy
  • Patent number: 10525270
    Abstract: According to some methods, for example, preprogrammed in a microprocessor element of an implantable cardiac pacing system, at least one of a number of periodic pacing threshold searches includes steps to reduce an evoked response amplitude threshold for evoked response signal detection. The reduction may be to a minimum value measurable above zero, for example, as determined by establishing a ‘noise floor’. Alternately, amplitudes of test pacing pulses and corresponding post pulse signals are collected and reviewed to search for a break, to determine a lower value to which the evoked response threshold may be adjusted without detecting noise. Subsequent to reducing the threshold, if no evoked response signal is detected for a test pulse applied at or above a predetermined maximum desirable pulse energy, an operational pacing pulse energy is set to greater than or equal to the maximum desirable in conjunction with a reduction in pacing rate.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: January 7, 2020
    Assignee: Medtronic, Inc.
    Inventors: Todd J Sheldon, Wade M Demmer
  • Patent number: 10512784
    Abstract: Systems, methods and implantable devices configured to provide cardiac resynchronization therapy and/or bradycardia pacing therapy. A first device located in the heart of the patient is configured to receive a communication from a second device and deliver a pacing therapy in response to or in accordance with the received communication. A second device located elsewhere is configured to determine an atrial event has occurred and communicate to the first device to trigger the pacing therapy. The second device may be configured for sensing the atrial event by the use of vector selection and atrial event windowing, among other enhancements. Exception cases are discussed and handled as well.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: December 24, 2019
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Stephen J. Hahn, Krzysztof Z. Siejko, William J. Linder, Keith R. Maile, Amy Jean Brisben, Keith L. Herrmann, Brendan E. Koop, Benjamin J. Haasl
  • Patent number: 10493286
    Abstract: An implantable medical device (IMD) automatically determines at least a portion of the parameters and, in some instances all of the parameters, of an exposure operating mode based on stored information regarding sensed physiological events or therapy provided over a predetermined period of time. The IMD may configure itself to operate in accordance with the automatically determined parameters of the exposure operating mode in response to detecting a disruptive energy field. Alternatively, the IMD may provide the automatically determined parameters of the exposure operating mode to a physician as suggested or recommended parameters for the exposure operating mode. In other instances, the automatically determined parameters may be compared to parameters received manually via telemetry and, if differences exist or occur, a physician or patient may be notified and/or the manual parameters may be overridden by the automatically determined parameters.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: December 3, 2019
    Assignee: Medtronic, Inc.
    Inventors: Michael L. Ellingson, Hyun J. Yoon
  • Patent number: 10441789
    Abstract: The present invention relates to an interface means, especially an interface means for a medical device, comprising at least one or more lines, whereby the lines are configured such that each line has at least one specific functionality and/or is able to connect a first connection means with a second connection means, and at least one grouping and/or redistributing means, wherein the at least one grouping and/or redistributing means is configured such that the lines can be grouped and/or redistributed onto one or more lines and/or the functionality of lines can be grouped and/or redistributed onto one or more lines, preferably onto at least one single line. Furthermore, the present invention relates to a method for communicating a plurality of signals, in particular power and/or data signals and/or control signals, over a plurality of lines.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: October 15, 2019
    Assignee: Medtronic Bakken Research Center, B.V.
    Inventor: Jeroen Jacob Arnold Tol
  • Patent number: 10434314
    Abstract: A medical system may include a first medical device such as a leadless cardiac pacemaker (LCP) that is configured to pace a patient's heart and a second medical device that is configured to have a capture threshold capability. The second medical device may monitor the patient's heart to ascertain whether the pacing pulses from the first medical device are capturing the heart, and to send the first medical device instructions to alter an energy level of subsequent pacing pulses.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: October 8, 2019
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Jacob M. Ludwig, Keith R. Maile
  • Patent number: 10426962
    Abstract: Methods, devices, and systems for performing pacing capture verification in implantable medical devices such as a leadless cardiac pacemakers using a pressure signal. An example medical device includes a pressure sensor and is configured to monitor for an evoked capture response using the pressure sensor following pace delivery. Various factors of the pressure waveform may be used including the use of threshold, templating, and slope, as well as comparing cross-domain sensed events including using a fiducial point from the pressure signal for comparison to an acoustic, electrical, or motion event, or the use of data obtained from a second device which may be implanted, wearable, or external to the patient.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: October 1, 2019
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Yinghong Yu, Michael J. Kane
  • Patent number: 10429395
    Abstract: Disclosed are methods, apparatuses, etc. for glucose sensor signal stability analysis. In certain example embodiments, a series of samples of at least one sensor signal that is responsive to a blood glucose level of a patient may be obtained. Based at least partly on the series of samples, at least one metric may be determined to assess an underlying trend of a change in responsiveness of the at least one sensor signal to the blood glucose level of the patient over time. A reliability of the at least one sensor signal to respond to the blood glucose level of the patient may be assessed based at least partly on the at least one metric assessing the underlying trend. Other example embodiments are disclosed herein.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: October 1, 2019
    Assignee: Medtronic Minimed, Inc.
    Inventors: Ying Luo, Rebecca K. Gottlieb, Meena Ramachandran, Chia-Hung Chiu, Nandita Dangui-Patel, Michael Kremliovsky, Jefferson Rose
  • Patent number: 10420945
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 24, 2019
    Assignee: Sorin CRM SAS
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Patent number: 10413734
    Abstract: A cardiac stimulation system and associated capture management method are provided in which capture and device longevity are improved. The device determines a series of capture thresholds. Capture threshold is the minimum pulse level (pulse energy or pulse amplitude or pulse width) that captures the heart. Each determination requires delivery of pacing pulses at several (at least two) known levels (pulse energy, pulse amplitude and/or pulse width) over time. The individual determined capture thresholds are combined into a set and the variability of the set is used to set the safety margin. The greater the variability in the capture thresholds, the bigger the safety margin.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: September 17, 2019
    Assignee: Medtronic, Inc.
    Inventors: Eric A Shilling, Karen J Kleckner
  • Patent number: 10384066
    Abstract: A non-invasive bodily-attached ambulatory medical monitoring and treatment device with pacing is provided. The device includes at least one therapy electrode; a memory storing information indicative of a patient's cardiac activity; circuitry for implementing a plurality of pacing routines, each pacing routine of the plurality of pacing routines corresponding to at least one cardiac condition of a plurality of cardiac conditions; and at least one processor coupled to the circuitry and configured to identify, within the information, at least one cardiac condition of the plurality of cardiac conditions; and respond to the identified cardiac condition in part by causing execution of at least one pacing routine corresponding to the identified cardiac condition.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: August 20, 2019
    Assignee: ZOLL MEDICAL CORPORATION
    Inventors: Jason T. Whiting, Thomas E. Kaib, Rachel H. Carlson, Gregory R. Frank
  • Patent number: 10350411
    Abstract: Devices, systems and methods for treating medical disorders, such as migraine or other primary headaches, or fibromyalgia, by noninvasive electrical stimulation of a vagus nerve, used in conjunction with the measurement of evoked potentials (EPs). The system comprises a stimulator that is applied to the surface of the patient's neck to apply electrical impulses sufficient to stimulate a cervical vagus nerve, scalp electrodes that are used to measure EPs that are evoked by that stimulation, feedback or biofeedback circuits to vary the stimulation based upon EP characteristics, and other sensory stimulation modalities that produce EPs. The system is preferably used to optimize the placement of the stimulator, to test whether a patient is a suitable candidate for treatment using vagus nerve stimulation, and to select the stimulation parameters that optimized acute or chronic treatment, e.g., by correcting an EP habituation deficit.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: July 16, 2019
    Assignee: Electrocore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Patent number: 10278217
    Abstract: A method, system and external instrument are provided. The method initiates a communication link between an external instrument (EI) and an implantable medical device (IMD), established a first connection interval for conveying data packets between the EI and IMD and monitors a connection criteria that includes at least one of a data throughput requirement. A battery indicator or link condition of the communications link is between the IMD and EI. The method further changes from the first connection interval to a second connection interval based on the connection criteria.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: April 30, 2019
    Assignee: Pacesetter, Inc.
    Inventors: Yongjian Wu, Chao-Wen Young, Jun Yang, Xing Pei, Reza Shahandeh
  • Patent number: 10183169
    Abstract: Systems and methods may facilitate selection of a vector for delivering electrical stimulation to a patient's heart. One illustrative method may include delivering electrical stimulation at a first voltage to each vector in a first set of two or more vectors of a multi-vector medical system, determining whether the delivered electrical stimulation at the first voltage resulted in capture for each of the vectors in the first set of two or more vectors, identifying those vectors of the first set of two or more vectors that were determined to result in capture as a second set of vectors, delivering electrical stimulation at a second voltage that is lower than the first voltage to each vector in the second set of vectors, and determining whether the delivered electrical stimulation at the second voltage resulted in capture for each of the vectors in the second set of vectors.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: January 22, 2019
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Holly E. Rockweiler, Sunipa Saha, Keith L. Herrmann, Yinghong Yu, Joel A. Krueger
  • Patent number: 10159847
    Abstract: An implantable medical device includes a housing, a power source and an operational circuit that is coupled to the power source. The operational circuit includes a first electrode terminal and a second electrode terminal, an output circuit configured to deliver an electrical stimulation therapy through the first and second electrode terminals and a control circuit configured to evaluate an electrical parameter associated with the output circuit and to control generation of the electrical stimulation therapy responsive to a result of the evaluated parameter. Among other things, the implantable medical device may modify a parameter of the therapy delivery in response to a result of the evaluation.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: December 25, 2018
    Assignee: Medtronic, Inc.
    Inventors: Marshall J. Rasmussen, Lonny V. Cabelka, Randolph E. Crutchfield, Jon E. Zimmer
  • Patent number: 10124174
    Abstract: An example of a system includes an implantable medical device (IMD) for implantation in a patient, where the IMD includes a cardiac pace generator, phrenic nerve stimulation (PS) sensor, a memory, and a controller, and where the controller is operably connected to the cardiac pace generator to generate cardiac paces. The controller is configured to provide a trigger for conducting a PS detection procedure and perform the PS detection procedure in response to the trigger. In performing the PS detection procedure the controller is configured to receive a signal from the sensor, detect PS using the signal from the sensor, and record the PS detection in storage within the IMD.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: November 13, 2018
    Assignee: Cardiac Pacemakes, Inc.
    Inventors: Holly Rockweiler, Sunipa Saha, Aaron R. McCabe, Krzysztof Z. Siejko
  • Patent number: 10118042
    Abstract: A method includes sensing a cardiac electrogram (EGM) signal of a patient via one or more electrodes on at least one implantable medical lead. An asystolic EGM signal is detected from the patient, and a lead integrity test of the at least one implantable medical lead is initiated in response to the asystolic EGM signal.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: November 6, 2018
    Assignee: Medtronic, Inc.
    Inventors: Bruce D. Gunderson, William J. Havel
  • Patent number: 10064567
    Abstract: Systems, methods, and graphical user interfaces are described herein for identification of optimal electrical vectors for use in assisting a user in implantation of implantable electrodes to be used in cardiac therapy. Cardiac improvement information may be generated for each pacing configuration, and one or more pacing configuration may be selected based on the cardiac improvement information. Optimal electrical vectors using the selected pacing configurations may be identified using longevity information generated for each electrical vector. Electrodes may then be implanted for use in cardiac therapy to form the optimal electrical vector.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: September 4, 2018
    Assignee: MEDTRONIC, INC.
    Inventors: Subham Ghosh, Jeffrey Gillberg, Manfred Justen, Eric Schilling
  • Patent number: 9913986
    Abstract: A particular implantable device includes one or more electrode connectors and multiple circuit elements within a housing. The implantable medical device may also include one or more switches, where each switch of the one or more switches is coupled between one or more of the multiple circuit elements and at least one electrode connector of the one or more electrode connectors.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: March 13, 2018
    Assignee: Cyberonics, Inc.
    Inventors: Eric Y. Chow, David L. Thompson
  • Patent number: 9913985
    Abstract: In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue in not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes as continued use may result in neural and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: March 13, 2018
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert Jay Greenberg, Kelly Hobart McClure, James Singleton Little, Rongqing Dai, Arup Roy, Richard Agustin Castro, John Reinhold, Kea-Tiong Tang, Sumit Yadav, Chunhong Zhou, Dao Min Zhou, Pishoy Maksy
  • Patent number: 9884194
    Abstract: On a channel of an implantable cardiac generator, a cardiac lead is replaced by a vagus nerve stimulation VNS lead. The control circuit controlling the stimulation circuit of this channel of the generator is configured to generate sequences of VNS neurostimulation bursts according to a specific profile, synchronized or not with the heart rate. The control circuit dynamically controls the initial load voltage of the reservoir capacitor so as to adjust to a constant target value the electrical charge delivered to the nerve by each stimulating pulse, from a pulse to the next one and from a burst to the next one. This improves the consistency of the physiological effects of neurostimulation despite significant variations that may occur in impedance at the electrode/vagus nerve interface.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: February 6, 2018
    Assignee: SORIN CRM SAS
    Inventors: Thierry Legay, Hervé Blumstein, Guillaume Chatalic, Christine Henry
  • Patent number: 9878164
    Abstract: Methods and device for determining a pacing vector for delivering an electrostimulation therapy are described. An implantable medical device may be configured to determine an anode capture threshold and a cathode capture threshold for a first anode and cathode pair of electrodes, switch a polarity of the first anode and cathode pair of electrodes, and determine an anode capture threshold and a cathode capture threshold for the first anode and cathode pair of electrodes having the switched polarity. The implantable medical device may be further configured to compare a cathodal capture threshold for the anode and cathode pair having the switched polarity to the anodal capture threshold of the first anode and cathode pair of electrodes and select either an anode or a cathode for delivering an electrostimulation therapy based at least in part on the comparison. Other methods and systems are also contemplated and described.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: January 30, 2018
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Holly E. Rockweiler, Shibaji Shome, Arjun D. Sharma, Deepa Mahajan, Sunipa Saha
  • Patent number: 9849294
    Abstract: Embodiments of the invention are related to medical systems and methods that can be used to control features of implanted medical devices, amongst other things. In an embodiment, the invention includes a medical system including an external medical device. The external medical device including a video output and a processor in communication with the video output. The system can be configured to display information through the video output as a graph, the graph comprising data representing pacing rates of an implantable device as a function of activity level over time. The system can further be configured to accept user input through direct manipulation of the graph. Other embodiments are also included herein.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: December 26, 2017
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jonathan H. Kelly, James Kalgren, David L. Perschbacher, James O. Gilkerson, Les N. Peterson
  • Patent number: 9820673
    Abstract: An implanted device for an organ of a patient including a housing. The device includes a detector having electrodes that have a varying distance over time between them which produces a detector signal based on electrical signals derived from the organ. The device includes a signal processor disposed in the housing in communication with the detector which determines admittance from the detector signal based on the varying distance over time between the electrodes. The device includes a drive circuit disposed in the housing to cause the electrodes to generate emitted electrical signals. A method for monitoring a patient's organ.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 21, 2017
    Assignee: Board of Regents, The University of Texas System
    Inventors: Marc D. Feldman, John Porterfield, Karthik Raghavan, Jonathan W. Valvano, John A. Pearce
  • Patent number: 9795791
    Abstract: The present disclosure provides systems and methods for cardiac stimulation. A cardiac stimulation device includes a plurality of electrodes, and a pulse circuit electrically coupled to the plurality of electrodes, the pulse circuit including a capacitor configured to charge to an initial charge level, deliver a test pulse having a first amplitude to the plurality of electrodes by only partially discharging, and subsequently deliver a backup pulse to the plurality of electrodes, the backup pulse having a second amplitude that is larger than the first amplitude.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: October 24, 2017
    Assignee: Pacesetter, Inc.
    Inventors: Benjamin T. Persson, Matthew G. Fishler
  • Patent number: 9776009
    Abstract: Systems, methods, and graphical user interfaces are described herein for non-invasively detecting phrenic nerve stimulation during cardiac pacing therapy. Phrenic nerve stimulation information may be generated for one or more electrical pacing vectors at one or more power configurations. The phrenic nerve stimulation information may be displayed to a user for use in configuring and/or evaluating cardiac pacing therapy.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: October 3, 2017
    Assignee: Medtronic, Inc.
    Inventors: Subham Ghosh, Vincent Splett
  • Patent number: 9764148
    Abstract: System and methods for energy adaptive communications between medical devices are disclosed. In one example, a medical device includes a communication module configured to deliver a plurality of pulses to tissue of a patient, where each pulse has an amount of energy. A control module operatively coupled to the communication module, may be configured to, for each delivered pulse, determine whether the delivered pulse produces an unwanted stimulation of the patient and to change the amount of energy of the plurality of pulses over time so as to identify an amount of energy that corresponds to an unwanted stimulation threshold for the pulses. The control module may then set a maximum energy value for communication pulses that is below the unwanted stimulation threshold, and may deliver communication pulses below the maximum energy value during communication with another medical device.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: September 19, 2017
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jeffrey E. Stahmann, Paul Huelskamp, Michael J. Kane, Keith R. Maile
  • Patent number: 9763588
    Abstract: Some embodiments described herein relate to a method that includes defining an electro-anatomical model of a heart. The electro-anatomical model can include conduction patterns for multiple patterns or phases identified by a measurement instrument. The electro-anatomical model can also include a voltage map of the heart. A portion of the heart containing a rotor can be identified based on circulation in one phase of the model. The rotor can be determined to be stable based on that portion of the heart having circulation in another phase of the model. The rotor can be characterized as a substrate rotor based on the rotor being stable and based on the voltage or a change in voltage at the portion of the heart containing the rotor. The rotor can be treated or ablated when the rotor is determined to be a substrate rotor.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: September 19, 2017
    Assignee: AFTx, Inc.
    Inventors: Jerome Edwards, Bao Nguyen, Paul Kessman, Thomas Kurian
  • Patent number: 9750943
    Abstract: An implantable medical device includes an activity sensor, a pulse generator, and a control module. The control module is configured to determine an activity metric from the activity sensor signal over an activity metric interval and compare the activity metric to a loss of capture detection threshold. The control module may detect loss of capture in response to the activity metric being less than the loss of capture detection threshold and increase a pacing pulse output in response to detecting the loss of capture.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: September 5, 2017
    Assignee: Medtronic, Inc.
    Inventors: Todd J Sheldon, David M Steinhaus