Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.

Abstract: An intra-body network system, comprises a first implantable medical device comprising a first communication circuitry and a second implantable medical device comprising a second communication circuitry. The first and second communication circuitries are configured to establish, in an implanted state of the first and second implantable medical devices, a communication for transmitting a communication signal from the first implantable medical device to the second implantable medical device and from the second implantable medical device to the first implantable medical device.

Abstract: Described herein are methods, devices, and systems that enable a remote non-implantable device (RNID) to send commands to a leadless pacemaker (LP) implanted within a patient. The RNID provide commands to a local non-implantable device (LNID) over one or more communication networks, and the LNID sends the commands to a second implantable device (SID) by transmitting radio frequency (RF) communication signals, which include the commands, using an antenna of the LNID. After receiving the commands from the LNID, by receiving RF communication signals that include the commands using an antenna of the SID, the SID transmits conductive communication signals, which include the commands, using electrodes of the SID. The LP receives the commands from the SID by receiving the conductive communication signals, which include the commands, using electrodes of the LP, and the LP performs command responses based on the commands that originated from the RNID.

Abstract: An implantable device for detecting an antenna misalignment with respect to a transmitting implantable device in a near field communication system comprises an antenna unit configured to receive signals through a body channel from the transmitting implantable device. The antenna unit comprises at least two pairs of electrodes configured to cover a blind angle of a radiation pattern of the transmitting implantable device. The implantable device further comprises a processing unit electrically coupled to the antenna unit and configured to detect the antenna misalignment of the at least two pairs of electrodes with respect to the transmitting implantable device.

Abstract: A programming device for programming an implantable medical device for stimulating a human or animal heart, wherein the following steps are performed: a) allowing to select one of at least two electrode lead configurations for stimulating a human or animal heart, wherein the at least two electrode lead configurations comprise a second electrode lead configuration in which at least one electrode lead is connected to an electrode lead port, the electrode lead port being configured to receive an electrode lead for stimulating a second cardiac region or detecting an electric signal at the second cardiac region, wherein the second cardiac region is a part of a ventricular conduction system of the heart, wherein the at least one electrode lead is intended to be implanted or is implanted in the second cardiac region; b) generating and releasing a notification signal if the second electrode lead configuration is selected.

Abstract: Disclosed herein is a method for transmitting information using a monitor brightness change. The method may include generating a transmission data frame structure for transmitting digital information, encoding the bit of the digital information, and converting the encoded bit of the digital information into a wireless signal that is a brightness change signal of blue (B) color, among red, green, and blue (RGB) for configuring colors on a monitor.

Abstract: Methods, systems, and devices that detect arrhythmic episodes and perform arrhythmia discrimination are described. Such a system includes a leadless pacemaker (LP) that senses a near-field electrogram (NF-EGM), and a non-vascular implantable cardioverter defibrillator (NV-ICD) that senses a far-field electrogram (FF-EGM). The LP determines cardiac activity information based on the NF-EGM and optionally also based on paced cardiac events caused by the LP.

Abstract: In one embodiment, an implantable medical device (IMD) comprises: therapeutic circuitry for controlling delivery of a medical therapy to a patient; a processor for controlling the IMD according to executable code; wireless communication circuitry for conducting wireless communications; and memory for storing data and executable code, wherein the executable comprises code for causing the processor to (1) communicate with an external programming device to define therapeutic settings for operation of the IMD, (2) perform validation operations on one or more instances of therapeutic settings by determining whether a respective instance of therapeutic settings is accompanied by permanent validation data or temporary validation data, wherein the validation operations comprise analyzing temporary validation data against at least one key of a plurality of cryptographic keys stored by the IMD.

Abstract: A biostimulator and a biostimulator system for septal pacing, is described. The biostimulator includes an articulation to allow an electrode axis of a pacing electrode to be directed differently than a housing axis of a housing. The housing contains electrical circuitry that is electrically connected to the pacing electrode. The differently directed axes allow the pacing electrode to affix to target tissue of an interventricular septal wall of a heart when the housing of the biostimulator is located near an apex of the heart. The articulation can include a flexible portion of an extension, a hinge, or a tether. Other embodiments are also described and claimed.

Abstract: A cardiac pacing system having a pulse generator for generating therapeutic electric pulses, a lead electrically coupled with the pulse generator having an electrode, a first sensor configured to monitor a physiological characteristic of a patient, a second sensor configured to monitor a second physiological characteristic of a patient and a controller. The controller can determine a pacing vector based on variables including a signal received from the second sensor, and cause the pulse generator to deliver the therapeutic electrical pulses according to the determined pacing vector. The controller can also modify pacing characteristics based on variables including a signal received from the second sensor.

Abstract: A method and medical device for determining a cardiac episode that includes sensing a cardiac signal, identifying the signal sensed during a predetermined time interval as one of a cardiac event, a non-cardiac event, and an unclassified event, determining a number of identified cardiac events, determining a number of identified unclassified events, and determining whether the cardiac episode is occurring in response to the number of identified cardiac events being greater than a cardiac event count threshold and the number of identified unclassified events being less than an unclassified event count threshold.

Abstract: One example method includes sending, by a first station (STA), a request frame to a wireless access point (AP). The request frame includes listen interval information, the listen interval information includes duration of a first listen interval, and the first STA is equipped with main radio and a wake-up receiver. The first STA receives a response frame sent by the AP, where the response frame carries an identity allocated by the AP to the first STA, and the identity of the first STA comprises an identity of the wake-up receiver of the first STA. The first STA controls the wake-up receiver to wake up within the first listen interval, and receives a wake-up beacon frame periodically sent by the AP.

Abstract: An implant system includes an implant device configured to generate a stimulation signal for a user using a power manager according to an operation mode based on biometric information of the user, and a wake-up device configured to switch the operation mode based on either one or both of an energy supply received through an external energy source different from the power manager and a result of counting a timer.

Abstract: A method for performing bronchial denervation, the method comprising an electromyography system having a cryoablation device with at least two recording electrodes. The electromyography system being configured to calculate a difference between a first electromyogram signal received from the first recording electrode and a second electromyogram signal received from the second recording electrode to generate a recorded electromyogram and compare the recorded electromyogram to a reference electromyogram.

Abstract: Systems and methods are described herein for use in synchronizing electrical activity monitored by a plurality of external electrodes with supplemental cardiac data for use in evaluating a patient's cardiac condition and configuring cardiac therapy. The supplemental cardiac data may include one or more markers indicative of the occurrence of cardiac events and/or data representative of representative of at least one of cardiac electrical signals, cardiac sounds, cardiac pressures, blood flow, and an estimated instantaneous flow waveform provided by a left ventricular assist device.

Abstract: Implantable medical devices (IMDs) described herein, and methods for use therewith described herein, reduce how often an IMD accepts a false message and/or reduce adverse effects of an IMD accepting a false message. Such IMDs can be leadless pacemakers (LPs), or implantable cardio defibrillators (ICDs), but are not limited thereto. Such embodiments can be used help multiple IMDs (e.g., multiple LPs) implanted within a same patient maintain synchronous operation, such as synchronous multi-chamber pacing.

Abstract: An intrathecal drug delivery system configured to monitor one or more physiological conditions of the patient to look for opportunities to time medicament delivery to coincide with patient activity inferring heightened cerebrospinal fluid oscillations, thereby improving dispersion of the medicament within the intrathecal space of the patient. The intrathecal drug delivery system includes an implantable medical pump, one or more physiological sensors, and an external programmer configured to program the implantable medical pump with a treatment protocol specifying at least one period of time during which a specified quantity of medicament is to be administered during which the implantable medical pump utilizes data from the one or more physiological sensors to time delivery of the medicament.

Abstract: A system is disclosed in one example which allows for modelling the wellness of a given Implantable Pulse Generator (IPG) patient. The modelling, embodied in an algorithm, uses one or more qualitative measurements and one or more quantitative measurements taken from the patient. The algorithm correlates the qualitative measurements to the various quantitative measurements to eventually, over time, learn which quantitative measurements best correlate to the qualitative measurements provided by the patient. The algorithm can then using current quantitative measurements predict a wellness factor or score for the patient, which is preferably weighted to favor the quantitative measurements that best correlate to that patient's qualitative assessment of therapy effectiveness. Additionally, the wellness factor may be used to adjust the stimulation program that the IPG device provides to the patient.

Abstract: An antenna for electrical coupling to a wireless communication circuit includes a first conductive strip segment having a first length, a second conductive strip segment having a second length different from the first length and coupled to the first conductive strip segment at a feed point to be electrically coupled to the drive node, and a third conductive strip segment having a third length less than both the first length and the second length. A first end of the third conductive strip is coupled to the feed point and a second end is coupled to circuit ground. The first conductive strip segment provides a first specified operating frequency range at a fundamental resonance mode corresponding to the first length plus the third length, and the second conductive strip segment provides a second specified operating frequency range at a fundamental resonance mode corresponding to the second length plus the third length.

Abstract: An implantable medical device comprises a functional device for carrying out a therapeutic or diagnostic function, and a communication device for communicating with a remote monitoring system. The communication device, at a start of initial operation of the implantable medical device, is enabled to establish a communication with said remote monitoring system. In this way an implantable medical device is provided which allows for including the implantable medical device in a remote monitoring while reducing a risk for a patient involved with attending to the patient for activating a remote monitoring function within the implantable medical device.

Abstract: A diagnostic system for use during a procedure associated with a cochlear implant includes a computing module and a base module configured to attach to a back side of the computing module and serve as a stand for the computing module. The computing module includes a display screen and a processor configured to execute a diagnostic application and direct the display screen to display a graphical user interface associated with the diagnostic application. The base module includes an interface unit configured to be communicatively coupled to the processor and to the cochlear implant while the base module is attached to the back side of the computing module.

Abstract: Implementations described and claimed herein provide systems and methods for patient device management. In one implementation, interrogation data is received from a cardiac implantable electronic device corresponding to an interrogation for a patient. The interrogation data includes device data for the cardiac implantable electronic device and patient specific data for the patient. The interrogation data is normalized into manufacturer independent interrogation data. The manufacturer independent interrogation data is associated with a permitted user. A processing status is assigned to the interrogation using the manufacturer independent interrogation data. The interrogation is aggregated into a category based on the processing status, and the category is associated with an action by the permitted user.

Abstract: Systems and methods include a cardiac device advisory management platform to receive and distribute data related to advisory notification(s) for an implanted cardiac device. Advisory notification data includes a device identifier and/or a lead identifier corresponding to the advisory notification. Upon receiving the advisory notification data, the clinic matches the device identifier and/or the lead identifier with patient data for patients enrolled with the clinic. One or more action indicators for various workflow procedures are generated and presented at a clinic user interface (UI) of the clinic device. Clinician inputs are received via the clinic UI to perform steps in response to the advisory notification, such as reviewing patient information, scheduling an in-office visit, and/or sending a notification to a patient device. A clinic behavior analysis is performed on the clinician inputs to generate information regarding the impact of the advisory notifications on the clinic workflow procedures.

Abstract: Systems and methods for improved user experience with rechargers for implantable medical devices. An external charging device for providing power to a rechargeable implantable device can determine a firmware state of the external charging device during recharging of the rechargeable implantable device, display a searching indication using a light indicator when the firmware state is determined to be in a searching state, display a charging indication using the light indicator when the firmware state is determined to be a charging state, and display an error indication using the light indicator when the firmware state is determined to be an error state. An optional user device application can provide complementary graphical user interfaces according to the firmware states.

Abstract: Some embodiments of the present invention include pairing two wireless devices by placing at least one of two devices in a pairing mode; performing at least one pairing motion event with at least one of the wireless devices to satisfy at least one pairing condition; detecting satisfaction of the at least one pairing condition; and pairing the two wireless devices in response to detecting satisfaction of the at least one pairing condition. Numerous other aspects are provided.

Abstract: A surgical feedback system includes a surgical instrument, a data source, and a surgical hub configured to communicably couple to the data source and the surgical instrument. The surgical hub has a control circuit, wherein the control circuit is configured to receive an input from the data source, analyze the received data against a stored set of data to optimize an outcome of a surgical procedure, and communicate a recommendation based on the analyzed data.

Abstract: The invention is an assembly for checking the functionality of a measuring object, that is a DUT, in a medical implant or at least one part of the medical implant. The assembly comprises a test signal generator, a test module that is connected to the test signal generator. The assembly has a first receiving structure with at least one contact electrode, into which an adapter rigidly connects to the DUT in a releasable manner which is inserted to form least one electrical contact. A control and analysis unit is connected to the test signal generator and to the test module in a wired or wireless manner.

Abstract: Systems and methods involve an intrathoracic cardiac stimulation device operable to provide autonomous cardiac sensing and energy delivery. The cardiac stimulation device includes a housing configured for intrathoracic placement relative to a patient's heart. A fixation arrangement of the housing is configured to affix the housing at an implant location within cardiac tissue or cardiac vasculature. An electrode arrangement supported by the housing is configured to sense cardiac activity and deliver stimulation energy to the cardiac tissue or cardiac vasculature. Energy delivery circuitry in the housing is coupled to the electrode arrangement. Detection circuitry is provided in the housing and coupled to the electrode arrangement. Communications circuitry may optionally be supported by the housing. A controller in the housing coordinates delivery of energy to the cardiac tissue or cardiac vasculature in accordance with an energy delivery protocol appropriate for the implant location.

Abstract: A medical device includes an antenna external to a case, package, or encapsulant for the electronic systems of the medical device. In one embodiment, a diabetes infusion pump is enclosed within a metal case, the pump including a processor and a communication module for wireless communications. An antenna is disposed in the delivery tubing of the pump outside the case with an antenna feed interconnecting the external antenna with the internal communication module. In another aspect, a thin film antenna is formed on the outer surface of the case in which a physiological parameter sensor, such as a glucose sensor, is enclosed. Multiple antennas may be used for communications on different frequencies.

Abstract: A system includes a vagus nerve stimulation (VNS) device configured to deliver a vagus nerve stimulation signal having an ON-period status and an OFF-period status, and a processor and a non-transitory computer readable memory. The memory stores instructions that, when executed by the processor, cause the system to synchronously record a first ECG profile of during the ON-period status and a second ECG profile during the OFF-period status, determine heart rate dynamics from the first and second ECG profiles, the heart rate dynamics including a plurality of R-R intervals in each ECG profile, generate display data configured to be displayed on a display, and transmit the display data to the display. The display data includes the R-R intervals for each of the first and second ECG profiles. The display data further includes a Poincaré plot.

Abstract: A detection system is adapted to perform methods for detecting defects in medical devices, during a reprocessing procedure, for example. The detection system may utilize computer-implemented instructions to determine the presence and nature of the defects, whether biological or mechanical, for example. The computer-implemented instructions may be adapted to include artificial intelligence and/or machine learning algorithms, and to process image data from digital inspection camera systems or proprietary camera systems. Upon identification of a defect present in a medical device, the detection system may notify users of the presence of the defect, as well as provide further recommended action to be taken regarding the medical device, if desirable, reducing potential instrument failure, patient injury or death. The disclosed detection system may be integrated into existing disinfection and sterilization systems currently used in medical facilities, such as hospitals and surgery centers, for example.

Abstract: A controller-transmitter transmits acoustic energy through the body to an implanted acoustic receiver-stimulator. The receiver-stimulator converts the acoustic energy into electrical energy and delivers the electrical energy to tissue using an electrode assembly. The receiver-stimulator limits the output voltage delivered to the tissue to a predetermined maximum output voltage. In the presence of interfering acoustic energy sources output voltages are thereby limited prior to being delivered to the tissue.

Abstract: A system and method for facilitating remote care management involving a patient having an implantable medical device (IMD). Upon establishing a remote care session between a patient controller device and a clinician programmer, wherein the clinician and the patient are remotely located with respect to each other, input from the patient or the clinician may be received via a user interface control associated with a particular functionality or aspect of the remote care session, including audiovisual (AV) communications, remote therapy programming, and related context. Responsive to the user input, a dialog interface is effectuated at one of the patient controller device and/or the clinician programmer. A user characterization label is received via the dialog interface from the user, wherein the user characterization label is indicative of a subjective assessment of the particular functionality of the remote care session, which may be used in generating user-labeled data pertaining thereto.

Abstract: The disclosure describes example devices, systems, and techniques for delivering electrical stimulation to a patient. In some examples, an IMD includes a housing having a main portion and projection extending from the main portion. The projection of the housing may carry an electrode. Stimulation circuitry may be disposed within the main portion of the housing where the stimulation circuitry may generate electrical stimulation deliverable via the electrode. Processing circuitry may be disposed within the main portion of the housing where the processing circuitry may control the stimulation circuitry to generate the electrical stimulation.

Abstract: A method of sending a medical data file from an external device to a computer system and storing the data file associated with a patient's identity, comprising: a) the computer system receiving information that a data file to be sent to the computer system from the external device (or from one of a set of external devices) is to be associated with the patient's identity; b) sending the data file from the external device to the computer system, with the data file identified as coming from the external device; c) the computer system finding the patient's identity from the identification of the image file as coming from the external device, and from the information that a data file to be associated with the patient's identity was to be sent from that external device; and d) the computer system storing the data file, associating the data file with the patient's identity.

Abstract: An implantable system including an atrial leadless pacemaker (aLP) and a ventricular leadless pacemaker (vLP), and methods for use therewith, are configured or used to terminate a pacemaker mediated tachycardia (PMT). In an embodiment, in response to the aLP detecting a PMT, the aLP initiates a PMT PA interval, and the aLP does not inform the vLP, via an i2i communication, of an atrial sensed event that caused the PMT to be detected, thereby preventing the vLP from initiating a PV interval during the PMT PA interval. The aLP selectively terminates the PMT PA interval. Additionally, the aLP informs the vLP, via an i2i communication, of an intrinsic atrial event being detected during the PMT PA interval, or of an atrial paced event being performed in response to the PMT PA interval expiring without an intrinsic atrial event being detected during the PMT PA interval.

Abstract: An implant system includes an implant device configured to generate a stimulation signal for a user using a power manager according to an operation mode based on biometric information of the user, and a wake-up device configured to switch the operation mode based on either one or both of an energy supply received through an external energy source different from the power manager and a result of counting a timer.

Abstract: An antenna for an implantable medical device, the antenna being configured for inductive wireless power transfer and/or near-field magnetic induction communication, the antenna comprising at least one coil or at least one set of coils, each coil comprising several windings. Furthermore, the present disclosure relates to an implantable medical device (IMD).

Abstract: Systems and methods involve an intrathoracic cardiac stimulation device operable to provide autonomous cardiac sensing and energy delivery. The cardiac stimulation device includes a housing configured for intrathoracic placement relative to a patient's heart. A fixation arrangement of the housing is configured to affix the housing at an implant location within cardiac tissue or cardiac vasculature. An electrode arrangement supported by the housing is configured to sense cardiac activity and deliver stimulation energy to the cardiac tissue or cardiac vasculature. Energy delivery circuitry in the housing is coupled to the electrode arrangement. Detection circuitry is provided in the housing and coupled to the electrode arrangement. Communications circuitry may optionally be supported by the housing. A controller in the housing coordinates delivery of energy to the cardiac tissue or cardiac vasculature in accordance with an energy delivery protocol appropriate for the implant location.

Abstract: Systems and methods for managing communication strategies between implanted medical devices. Methods include temporal optimization relative to one or more identified conditions in the body. A selected characteristic, such as a signal representative or linked to a biological function, is assessed to determine its likely impact on communication capabilities, and one or more communication strategies may be developed to optimize intra-body communication.

Abstract: The present teaching relates to method, system, medium, and implementations for managing a user machine dialogue. A request is received by a server from a device for a response to be directed to a user engaged in a dialogue with the device. The request includes information related to a current state of the dialogue. The response is determined based on a dialogue tree and the information related to the current state of the dialogue. A sub-dialogue tree, which corresponds to a portion of the dialogue tree, is then created based on the response and the dialogue tree and is then used to generate a local dialogue manager for the device. The response, the sub-dialogue tree, and the local dialogue manager are then sent to the device, wherein the local dialogue manager, once deployed on the device, is capable of driving the dialogue with the user based on the sub-dialogue tree on the device.

Abstract: The present teaching relates to method, system, medium, and implementations for managing a user machine dialogue. Sensor data is received at a device, including an utterance representing a speech of a user engaged in a dialogue with the device. The speech of the user is determined based on the utterance and a response to the user is searched by a local dialogue manager residing on the device against a sub-dialogue tree stored on the device. The response, if identified from the sub-dialogue tree, is rendered to the user in response to the speech. A request is sent to a server for the response, if the response is not available in the sub-dialogue tree.

Abstract: The implant including an elongated tubular body, having at a first end a releasable device connected to an installation lead, and at a second end a member for anchoring to a heart wall, the tubular body housing a frame supporting an electronic unit. The implant further comprises an accelerometer. This accelerometer comprises a piezoelectric blade extending in cantilever from an embedding section of the frame, in a direction going from the first end to the second end.

Abstract: In one example, a circuit includes a first node to receive an analog signal that is an amplitude modulated radio-frequency signal for a digital signal. An output node is configured to provide an output signal indicative of rising and falling edges of an envelope of the analog signal. The rising and falling edges are indicative of rising and falling edges of the digital signal. A first current path is disposed between a power supply node and the first node. The first current path includes a first transistor coupled between the first node and a first bias source. The first bias source is coupled between the first transistor and the power supply node. The output node is coupled to a first intermediate node in the first current path between the transistor and the first bias source. A control terminal of the first transistor is coupled to the output node via a feedback network.

Abstract: Provided are a method for supplying power to an implantable medical device and a power supply system for an implantable medical device. The power supply system supplies a constant power to the implantable medical device even when there is a movement in a body, by using a wireless power transmitter unit, a wireless power receiver unit, and a piezoelectric sensor unit stacked at the wireless power receiver unit.

Abstract: A method for managing power during communication with an implantable medical device, including establishing a communications link, utilizing a power corresponding to a session start power, to initiate a current session between an implantable medical device (IMD) and external device. A telemetry break condition of the communications link is monitored during the current session. The power utilized by the IMD is adjusted between low and high power levels, during the current session based on the telemetry break condition. The number of sessions is counted, including the current session and one or more prior sessions, in which the IMD utilized the higher power level, and a level for the session start power to be utilized to initiate a next session following the current session is adaptively learned based on the counting of the number of sessions.

Abstract: A system, such as an IMD system, includes a tissue conductance communication (TCC) transmitter configured to generate a beacon signal by generating a carrier signal and modulating a first property of the carrier signal according to a first type of modulation. The TCC transmitter is configured to generate a data signal subsequent to the beacon signal by generating the carrier signal and modulating a second property of the carrier signal different than the first property according to a second type of modulation different than the first type of modulation.

Abstract: Disclosed herein are implantable medical devices (IMDs) including a receiver and a battery, and methods for use therewith. The receiver includes first and second differential amplifiers, each of which monitors for a predetermined signal within a frequency range and drains power from the battery while enabled, and while not enabled drains substantially no power from the battery. To remove undesirable input offset voltages, each of the differential amplifiers, while enabled, is selectively put into an offset correction phase during which time the predetermined signal is not detectable by the differential amplifier. At any given time at least one of the first and second differential amplifiers is enabled without being in the offset correction phase so that at least one of the differential amplifiers is always monitoring for the predetermined signal. In this manner, the receiver is never blind to signals, including the predetermined signals, sent by another IMD.

Abstract: An apparatus for adaptive streaming in multiple narrowband wireless communication environment comprises a communication unit configured to perform multi-communication with a server using a TCP and an UDP, a network monitor unit configured to collect state information on each of a plurality of narrowband networks, and a parameter control unit configured to: based on the collected state information on each of the plurality of narrowband networks, select a quality of video segment to be requested and one of the TCP protocol and the UDP protocol to be used in each of the plurality of narrowband networks, or determine a data size of redundant data for data loss restoration for each of the plurality of narrowband networks.

Abstract: Devices that communicate using wireless proximal communications measure pulse width to find distortion in the received signal. The distortion may be due to the devices being too close to one another for a transmission power level currently being used which causes ringing of a receiving coil. The distortion may be used to find a correction that the receiving device may use to correct for the distortion in the received pulse train when decoding the pulse train. The distortion may be used to adjust a transmission power level of the receiving device and/or to send an instruction to the transmitting device to adjust the power transmission power level of the transmitting device. The distortion may be used for other purposes including determining a device depth and/or location for an implanted device, such as an implantable medical device within a body of a patient.