Abstract: A biostimulator, such as a leadless cardiac pacemaker, including a fixation element and an electrode mounted on a resilient scaffold, is described. The fixation element and the resilient scaffold are coupled to a housing of the biostimulator. The resilient scaffold can support the electrode against a target tissue at a location that is radially offset from a location where the fixation element anchors the housing to the target tissue. A flexibility of the resilient scaffold allows the electrode to conform to a shape and movement of the target tissue when the housing is rigidly fixed to the target tissue by the fixation element. The resiliently supported electrode that is radially offset from the anchor point can reliably pace the target tissue without piercing the target tissue. Other embodiments are also described and claimed.

Abstract: The hybrid battery system includes a primary battery pack, a secondary battery pack, a battery control unit, a battery pack positive terminal, and a battery pack negative terminal. The battery control unit includes a management module and a variable resistor. The primary battery pack supplies power at lower temperatures, while the secondary battery pack supplies power at higher temperatures. The primary battery pack is unsafe at higher temperatures, and the primary cells within the primary battery pack are modified to mitigate the dangers that previously rendered the primary battery pack unusable in a hybrid battery pack at higher temperatures. The invention includes the method of safely operating the hybrid battery system with the modified primary battery cells of the primary battery pack.

Abstract: A relatively compact implantable medical device includes a fixation member formed by a plurality of fingers mounted around a perimeter of a distal end of a housing of the device; each finger is elastically deformable from a relaxed condition to an extended condition, to accommodate delivery of the device to a target implant site, and from the relaxed condition to a compressed condition, to accommodate wedging of the fingers between opposing tissue surfaces at the target implant site, wherein the compressed fingers hold a cardiac pacing electrode of the device in intimate tissue contact for the delivery of pacing stimulation to the site. Each fixation finger is preferably configured to prevent penetration thereof within the tissue when the fingers are compressed and wedged between the opposing tissue surfaces. The pacing electrode may be mounted on a pacing extension, which extends distally from the distal end of the device housing.

Abstract: The module comprises a pendular unit with an elastically deformable piezoelectric beam having a clamped end and an opposite, free end, coupled to an inertial mass. The beam produces an oscillating electrical signal collected by electrodes, which is rectified and regulated to output a voltage for charging a battery. The number and configuration of the electrodes (T1, T2, B1, B2, N) carried by the piezoelectric beam define a plurality of pairs of electrodes between which a corresponding plurality of said oscillating signals can be simultaneously collected. A switching matrix, as a function of an input command, selectively switches the plurality of pairs of electrodes between each other according to a plurality of different series (S), parallel (P) and/or series-parallel (SP) configurations, the selected configuration being that which maximizes the power sent to the battery as a function of the voltage level (VBAT) present at the terminals of the latter.

Abstract: Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.

Abstract: The present disclosure provides improved leadless pacemakers. In one embodiment, the leadless pacemaker includes an implantable pulse generator releasably coupled to a collapsible anchoring device. The collapsible anchoring device includes at least one pacing electrode configured to contact tissue at a target site.

Abstract: A biostimulator, such as a leadless cardiac pacemaker, including a fixation element and an electrode mounted on a resilient scaffold, is described. The fixation element and the resilient scaffold are coupled to a housing of the biostimulator. The resilient scaffold can support the electrode against a target tissue at a location that is radially offset from a location where the fixation element anchors the housing to the target tissue. A flexibility of the resilient scaffold allows the electrode to conform to a shape and movement of the target tissue when the housing is rigidly fixed to the target tissue by the fixation element. The resiliently supported electrode that is radially offset from the anchor point can reliably pace the target tissue without piercing the target tissue. Other embodiments are also described and claimed.

Abstract: A reconfigurable implantable system for ultrasonic power control and telemetry includes a charging device that includes an ultrasonic transducer to transmit and receive ultrasonic signals transmitted through a biological body, and a signal generator to drive the ultrasonic transducer to transmit an ultrasonic charging signal through the biological body. The system further includes an implantable device configured to communicate wirelessly with the charging device through the biological body via an ultrasonic communication link between the implantable device and the charging device. An implantable ultrasonic transducer receives the ultrasonic charging signal from the charging device and transmits ultrasonic signals through the biological body. A power unit coupled to the ultrasonic transducer harvests energy from the received ultrasonic charging signal when the implantable device is in an energy harvesting mode.

Abstract: An energy harvester includes a pendular unit subjected with a piezoelectric beam coupled to an inertial mass. On the clamped side of the beam, a beam frame includes two pressing elements between which the beam is taken in sandwich, each including i) an intermediate part, an internal face of which presses on a corresponding face of the beam, and ii) a pressure plate, an internal face of which presses on an external face of the intermediate part, a printed circuit board being interposed between them. The intermediate parts and the pressure plates are passed through by at least one common transverse bore receiving a locking pin. The intermediate parts, the pressure plates and the pin are each massive metal parts ensuring a direct electrical and mechanical contact with the electrodes of the beam and with the printed circuit boards.

Abstract: The present technology generally includes devices, systems, and methods for providing electrical stimulation to the left ventricle of a human heart in a patient suffering from Left Bundle Branch Block (LBBB). In particular, the present technology includes an implantable receiver-stimulator and an implantable controller-transmitter for leadless electrical stimulation of the heart. The receiver-stimulator can include one or more sensors capable of detecting the electrical conduction of the heart and the receiver-stimulator can be configured to pace the stimulation of the left ventricle based off the sensed electrical conduction to achieve synchronization of the left and right ventricles.

Abstract: A high power kinetic energy generating device comprises: a magnetic group, a magnetically permeable cavity body, and a coil. The magnetic group comprises an upper magnetically permeable member, a lower magnetically permeable member, and a permanent magnet member. A magnetic gap is defined between the upper magnetically permeable member and the lower magnetically permeable member. The magnetically permeable cavity body and the magnetic group form a magnetically permeable cavity. The magnetically permeable cavity body further comprises a middle column arranged in the magnetically permeable cavity. The coil is also arranged in the magnetically permeable cavity, and surrounds the middle column. The middle column extends into the magnetic gap.

Abstract: A P-wave centric subcutaneous insertable cardiac monitor (ICM) for use in performing long term electrocardiographic (ECG) monitoring is disclosed. The length of the monitoring performed by the ICM is extended, potentially for a life time of the patient, and the functionality of the ICM is enhanced, by including an internal energy harvesting module in the ICM. The energy harvesting module harvests energy from outside the ICM, and provides the harvested energy for powering the circuitry of the ICM, either directly or by recharging a power cell within the ICM. As the circuitry of the ICM requires a low amount of electrical power, the harvested energy can be sufficient to support the functioning of the ICM even when the electrical power stored on the ICM at the time of implantation runs out.

Abstract: An energy harvester converts into electrical energy the external stresses applied to the implant at the rhythm of the heartbeats. This harvester comprises an inertial unit. A transducer provides an oscillating electrical signal that is rectified and regulated, for powering the implant and/or charging a battery. The instantaneous variations of this electrical signal between two heartbeats are analyzed inside successive time windows, to derive therefrom a physiological parameter and/or a physical activity parameter of the patient with the implant, in particular as a function of a peak of amplitude of the first oscillation of the electrical signal, and of the level of this signal after the bounce phase of the signal oscillation.

Abstract: The device includes an energy harvesting module with a pendular unit formed of an elastically deformable piezoelectric beam associated with an inertial mass. A multifunction part includes an axial through-recess with inner bearing surfaces opposite respective outer faces of the beam. These bearing surfaces having an increasing transverse spacing, such as, during an oscillation cycle, the beam comes into contact with one of the bearing surfaces, hence reducing the free length of the beam as the bending of the latter goes along. The multifunction part also allows rationalizing the manufacturing and the assembly of the capsule, with high-level integration of the inner components of the implant.

Abstract: A tray, a tray assembly, a battery pack assembly and a vehicle are provided. The tray includes a bottom plate having a plurality of sub-bottom plates and a flow channel in at least one of the plurality of sub-bottom plates. The at least one of the plurality of sub-bottom plates is configured to support a battery assembly. The tray further includes a frame disposed around and configured to support the bottom plate. The tray provides a reduced volume requirement on the cavity for holding the battery assembly. The flow channels are arranged more concisely, and a water cooling mode and an air cooling mode are employed in the tray.

Abstract: By a microbial fuel cell including: an anode electrode that includes, as a catalyst, current-generating bacteria supplied from soil or mud, and oxidizes an organic fuel supplied from soil or mud; and a cathode electrode that reduces oxygen supplied from air or water, the microbial fuel cell having an oxygen permeation restricting layer between the anode electrode and the cathode electrode facing each other, it is possible to provide, at low cost, a microbial fuel cell having high power generation performance due to direct power generation from soil or mud and capable of being thinned and miniaturized.

Abstract: A system for providing energy to a bio-implantable medical device includes an acoustic energy delivery device and a bio-implantable electroacoustical energy converter. The acoustic energy delivery device generates acoustic energy with a multi-dimensional array of transmitting electroacoustical transducers. The acoustic energy is received by one or more receiving electroacoustical transducers in the bio-implantable electroacoustical energy converter. The receiving electroacoustical transducers convert the acoustic energy to electrical energy to power the bio-implantable medical device directly or indirectly. An external alignment system provides lateral and/or angular positioning of an ultrasound energy transmitter over an ultrasound energy receiver. The acoustic energy transmitter alignment system comprises either or both x-y-z plus angular positioning components, and/or a substantially multi-dimensional array of transmitters plus position sensors in both the transmitter and receiver units.

Abstract: An electronic device with a circuit for supplying electric power, with a variable capacitor, by alternating mechanical movement. The supply includes, in the form of passive components and without synchronizing structure: generating branch including in series the variable capacitor and a biasing capacitor, connected in parallel to a rectifier circuit and a storage branch, between: a base node, on the variable capacitor side; an output node, on the biasing capacitor side; unidirectional charge return branch: to the generating branch, via a biasing node between the variable capacitor and the biasing capacitor; from the rectifier, receiving a part of the electrical energy produced. A circuit includes a voltage multiplier connected to the biasing node for applying a voltage that is multiplied relative to that existing between the output node; and the base node or one of the ends of the storage branch.

Abstract: Embodiments of the invention provide an energy harvesting mechanism comprising a central conductive element and a plurality of transductive elements. Each transductive element is positioned to be in contact with a corresponding peripheral length segment of the central conductive element. Also each transductive element is deformable in a characteristic radial direction to convert its deformation into a corresponding electrical signal. The plurality of transductive elements are arranged so that any one of the plurality of transductive elements is capable of being deformed in the characteristic radial direction to trigger the corresponding electrical signal. Embodiments of the mechanism can be used for harvesting energy from a variety of bio-kinetic events such as a heartbeat, respiration, muscle contraction or other movement. Such embodiments can be used for powering a variety of implanted medical devices such as pacemakers, defibrillators and various monitoring devices.

Abstract: Various medical implants and methods of using the implants are disclosed. In an embodiment, the implants include piezoelectric polymers for treating unwanted medical conditions of a patient. The medical implants may be delivered to an organ of the patient to treat conditions of those organs.

Abstract: A medical implant including an implant body for insertion into a human and/or animal body. The implant body includes at least one first and at least one second contact portion, wherein the at least one first and the at least one second contact portions contact two tissue regions performing a relative movement with respect to one another. The at least one first and the at least one second contact portions are movable relative to one another, wherein a relative movement of the contact portions may be converted into an electrical signal.

Abstract: Embodiments of the invention provide apparatus, systems and methods for harvesting energy from bio-kinetic events to power various implanted medical devices. One embodiment provides an energy harvesting mechanism for a cardiac pacemaker comprising an energy converter and a signal path component. The energy converter is positionable inside a human body and configured to generate electric power signals in response to a bio-kinetic event of the human body such as a heart beat, respiration or arterial pulse. The converter can comprise a piezoelectric material which generates electricity in response to mechanical deformation of the converter. The converter can also have a power generation characteristic that is matched to the frequency of the bio-kinetic event. For heart beat powered applications, the power generation characteristic can be matched to the physiologic range of pulse rates.

Abstract: A system includes a first implantable medical device configured to receive a first far field radiative signal at a first frequency from an external transmitter to charge a first charge storage device. The first implantable medical device includes a first therapy delivery unit powered by the first charge storage device. The first therapy delivery unit delivers a first therapy to a first target tissue of a patient. The system also includes a second implantable medical device configured to receive a second far field radiative signal at a second frequency from the external transmitter to charge a second charge storage device. The second implantable medical device includes a second therapy delivery unit powered by the second charge storage device. The second therapy delivery unit delivers a second therapy to a second target tissue of the patient.

Abstract: A method of manufacturing an implantable medical device having reduced MRI image distortion, includes producing an implantable medical device. The implantable medical device has a configuration that comprises a housing and one or more internal components disposed within the housing. The configuration is based upon a design process that includes creating a first prototype, determining the aggregate relative magnetic permeability of the first prototype, and modifying the design of the first prototype by at least one of (a) selecting and adding a diamagnetic shimming material to the first prototype or (b) repositioning one or more internal components of the first prototype. Modifying the design results in a modified design that is the configuration for the implantable medical device.

Abstract: An intracorporeal capsule for placement in a heart and for energy harvesting using blood pressure variations is shown and described. The capsule includes a capsule body and a piezoelectric strip coupled to a rigid surface for receiving blood pressure force. The piezoelectric strip is normally perpendicular to the direction of the force on the rigid surface. The piezoelectric strip is disconnected from the capsule body along at least two edges of the piezoelectric strip such that the blood pressure force can move the rigid surface, and thereby deform the piezoelectric strip for energy harvesting.

Abstract: This disclosure describes techniques and systems for extracting energy from the endocochlear potential (EP) in animal subjects (e.g., human subjects) and using the extracted energy to operate circuits (e.g., electronic device, sensors, and transmitters). The subject matter of this disclosure is embodied, for example, in a system for extracting energy from an endocochlear potential of an animal, wherein the system includes a pair of electrodes, and a circuit coupled to the pair of electrodes. The circuit includes a boost converter, an energy buffer component configured to receive voltage from the boost converter, a start-up rectifier configured to provide voltage to the energy buffer component, and a control component configured to provide control signals to the boost converter. The power extracted from the endocochlear potential is equal or larger than the quiescent power of the circuit.

Abstract: A device for generating power from intraluminal pressure changes may comprise: (a) a generator configured for intraluminal disposal; and (b) an intraluminal pressure change-receiving structure. A system for generating power from intraluminal pressure changes may comprise: means for receiving an intraluminal pressure change; and (b) means for converting the intraluminal pressure change into energy with an intraluminal generator.

Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

Abstract: A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive.

Abstract: This disclosure is directed to a self-powered internal medical device. An example device may comprise at least an energy generation module and an operations module to at least control the energy generation module. The energy generation module may include a structure to capture certain molecules in the organic body based at least on size, the structure including a surface of the device in which at least one opening is formed. The at least one opening may be sized to only capture certain molecules. The operations module may initiate oxidation reactions in the captured molecules to generate current for device operation or for storage in an energy storage module. Thermoelectric generation circuitry in the energy generation module may also use heat from the reaction to generate a second current. The operations module may control operation of a sensor module and/or communication module in the device based on the generated energy.

Abstract: A tube-structured battery to be inserted into a living body is provided. The tube-structured battery includes: a biofuel battery part which generates electric energy by using biofuel in the blood passing through an internal space of the tube structure; a transformer circuit part which adjusts a voltage or current density by using the generated electric energy; and a secondary battery part which is charged with the electric energy by using the adjusted voltage or current density to store the electric energy, wherein the tube-structured battery is inserted into the living body or a blood vessel of the living body.

Abstract: A intracorporeal medical capsule is shown and described. The capsule includes an elastically deformable base having an anchor at one end and coupled to a capsule body at the opposite end. An energy harvesting element is elastically coupled to a seismic mass within the capsule body. The elastically deformable base increases energy harvested at the energy harvesting element due to elastic movement of the capsule body in the presence of blood flow around the capsule body.

Abstract: A leadless cardiac pacemaker comprises a housing, a plurality of electrodes coupled to an outer surface of the housing, and a pulse delivery system hermetically contained within the housing and electrically coupled to the electrode plurality, the pulse delivery system configured for sourcing energy internal to the housing, generating and delivering electrical pulses to the electrode plurality. The pacemaker further comprises an activity sensor hermetically contained within the housing and adapted to sense activity and a processor hermetically contained within the housing and communicatively coupled to the pulse delivery system, the activity sensor, and the electrode plurality, the processor configured to control electrical pulse delivery at least partly based on the sensed activity.

Abstract: Embodiments of the invention provide apparatus, systems and methods for harvesting energy from bio-kinetic events to power various implanted medical devices. One embodiment provides an energy harvesting mechanism for a cardiac pacemaker comprising an energy converter and a signal path component. The energy converter is positionable inside a human body and configured to generate electric power signals in response to a bio-kinetic event of the human body such as a heart beat, respiration or arterial pulse. The converter can comprise a piezoelectric material which generates electricity in response to mechanical deformation of the converter. The converter can also have a power generation characteristic that is matched to the frequency of the bio-kinetic event. For heart beat powered applications, the power generation characteristic can be matched to the physiologic range of pulse rates.

Abstract: Embodiments of the invention provide an energy harvesting mechanism comprising a central conductive element and a plurality of transductive elements. Each transductive element is positioned to be in contact with a corresponding peripheral length segment of the central conductive element. Also each transductive element is deformable in a characteristic radial direction to convert its deformation into a corresponding electrical signal. The plurality of transductive elements are arranged so that any one of the plurality of transductive elements is capable of being deformed in the characteristic radial direction to trigger the corresponding electrical signal. Embodiments of the mechanism can be used for harvesting energy from a variety of bio-kinetic events such as a heartbeat, respiration, muscle contraction or other movement. Such embodiments can be used for powering a variety of implanted medical devices such as pacemakers, defibrillators and various monitoring devices.

Abstract: An implantable medical device includes a housing formed of a first material and a first electronic component provided within the housing. The implantable medical device also includes a second material provided in contact with at least a portion of the housing. At least one of the housing and the first electronic component has a magnetic permeability in a magnetic field that differs from the magnetic permeability of water. The second material is provided in an amount effective to reduce MRI image distortion caused by the implantable medical device.

Abstract: An implantable microstimulator configured for implantation beneath a patient's skin for tissue stimulation to prevent and/or treat various disorders, uses a self-contained power source. Periodic or occasional replenishment of the power source is accomplished, for example, by inductive coupling with an external device. A bidirectional telemetry link allows the microstimulator to provide information regarding the system's status, including the power source's charge level, and stimulation parameter states. Processing circuitry automatically controls the applied stimulation pulses to match a set of programmed stimulation parameters established for a particular patient. The microstimulator preferably has a cylindrical hermetically sealed case having a length no greater than about 27 mm and a diameter no greater than about 3.3 mm. A reference electrode is located on one end of the case and an active electrode is located on the other end.

Abstract: An implantable device that includes a plurality of conduits, a plurality of chambers, and a control unit. The blood through the plurality of conduits and the chambers collect the ingredient information of the blood according to the blood through the conduits. The chambers transfer the ingredient information of the blood to the control unit to analysis. The chamber includes two electrodes, the chamber exploits a reverse theorem to force the glucose of the blood generates a plurality of charges flowing between the electrodes and further to generate a current in the chamber. Thus, the implantable device can achieve the goal of the self-electricity-generation.

Abstract: A medical lead screening connector includes a housing, a plurality of lead receptor channels disposed within the housing, a cover hingedly attached to the housing, and a base element rotationally attached to the housing. Each lead receptor channel includes at least two lead receptor contacts. A conductor cable is attached to and extends away from the housing. The base element is configured to reel in the conductor cable upon rotation of the base element.

Abstract: An implantable, rechargeable medical system comprised of an implanted device, a power storage device connected to the implantable device, and a charging device operatively connected to the electrical storage device. The charging device can be thermoelectric and have components for transferring thermal energy from an intracranial heat accumulator to an extra-cranial heat sink, for generating an electrical current from the thermal energy transfer, for charging the electrical storage device using the electrical current, for measuring power generation, usage and reserve levels, for measuring temperatures of the intracranial and extra-cranial components, for physically disrupting heat transfer and charging operations, and for generating signals relevant to the status of temperature and electricity transfer in relation to energy generation criteria. The system may also have long-range and short range wireless power harvesting capability as well as movement, and photovoltaic charging capability.

Abstract: A device is presented for evaluating whether an episode of sleep apnea is occurring in a patient suffering from chronic sleep apnea disorder, for delivery of appropriate therapy. The device includes circuitry adapted to respond to a cardiac signal generated by the heart. Switching circuitry diverts passage of the heart signal through both a high impedance path and a substantially lower impedance path, and a differential amplifier processes the resulting signal pairs to ascertain the difference in magnitude between the two signals of each pair. An analyzer thereof determines changes in the patient's ventilation, from which inordinately reduced patient ventilation is detected to assess possible occurrence of an episode of sleep apnea. If the analyzer denotes change of ventilation between otherwise regular respiratory cycles, an actual episode of sleep apnea is indicated.

Abstract: An implantable device is provided, the device includes a plurality of conduits, a plurality of chambers, and a control unit. The blood through the plurality of conduits and the chambers collect the ingredient information of the blood according to the blood through the conduits. The chambers transfer the ingredient information of the blood to the control unit to analysis. The chamber includes two electrodes, the chamber exploits a reverse theorem to force the glucose of the blood generates a plurality of charges flowing between the electrodes and further to generate a current in the chamber. Thus, the implantable device can achieve the goal of the self-electricity-generation.

Abstract: A transcutaneous energy transfer system, transcutaneous charging system, external power source, external charger and methods of transcutaneous energy transfer and charging for an implantable medical device and an external power source/charger. The implantable medical device has a secondary coil adapted to be inductively energized by an external primary coil at a carrier frequency. The external power source/charger has a primary coil and circuitry capable of inductively energizing the secondary coil by driving the primary coil at a carrier frequency adjusted to the resonant frequency to match a resonant frequency of the tuned inductive charging circuit, to minimize the impedance of the tuned inductive charging circuit or to increase the efficiency of energy transfer.

Abstract: A device for altering cardiac performance includes an energy absorbing element which absorbs cardiac pumping energy from at least a portion of the heart. The energy may be delivered to another part of the body, such as another portion of the heart, to perform useful work such as providing blood pumping assistance.

Abstract: An implantable microstimulator configured for implantation beneath a patient's skin for tissue stimulation to prevent and/or treat various disorders, uses a self-contained power source. Periodic or occasional replenishment of the power source is accomplished, for example, by inductive coupling with an external device. A bidirectional telemetry link allows the microstimulator to provide information regarding the system's status, including the power source's charge level, and stimulation parameter states. Processing circuitry automatically controls the applied stimulation pulses to match a set of programmed stimulation parameters established for a particular patient. The microstimulator preferably has a cylindrical hermetically sealed case having a length no greater than about 27 mm and a diameter no greater than about 3.3 mm. A reference electrode is located on one end of the case and an active electrode is located on the other end.

Abstract: Methods and apparatus for improving cognitive function within a human. The invention utilizes an implanted device, such as an implantable signal generator or an implantable pump, to affect tissue elements within a Papez circuit of the human brain as well as tissue upstream or downstream from the Papez circuit. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various symptoms of the cognitive disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation and/or drug therapy.

Abstract: An implantable medical device includes a housing having a coating selectively provided on only a portion of the housing and a plurality of electronic components provided within an interior space defined by the housing. A first of the electronic components is a charging or telemetry coil and a second of the electronic components is a circuit board. The coating is provided on the housing in a first region near a component of the circuit board and is not provided on the housing in a second region near the charging or telemetry coil. The coating has a magnetic permeability suitable to and is provided in an amount effective to reduce MRI image distortion caused by the component of the circuit board.

Abstract: Method and apparatus for converting the output of a thermoelectric generator to voltages compatible with implantable medical devices is provided. One apparatus includes an implantable thermoelectric generator. The apparatus includes an input terminal for receiving an input voltage generated by a thermoelectric energy converter and a charging inductor connected in series with the input terminal. The apparatus also includes a switching Field Effect Transistor (FET) connected to the inductor, and a capacitor connected to the FET and the input terminal via a diode. The FET is switched with a frequency and duty cycle such that a voltage level at an output terminal is compatible with an implantable medical device. According to various embodiments, the FET is switched using a closed loop feedback system that controls the frequency and duty cycle based on an observed voltage level at the output terminal. Other aspects and embodiments are provided herein.

Abstract: A thermoelectric power source for generating power for use by at least one load device including an implantable thermoelectric unit having at least one thermoelectric device configured to be electrically coupled to the at least one load device, and at least one impedance matching device constructed and arranged to match an output impedance of the thermoelectric device with an input impedance of the load device.

Abstract: A system for harvesting of natural power of the heart movement to be deployed entirely inside or outside human heart. The means and the method for the system deployment/extraction are provided. The system is implemented as storage “satellite” container/housing/carrier unit for piezoelectric power generator, power storage and spare volume for transported cardio stimulator devices. The piezoelectric power generator comprises embedding circuits containing the diode bridge, controller, capacitor and a number of piezo-electric elastic ceramic rods—“leaflets”, originally strained asymmetrically with accordance to the heart 3D geometry in order to obtain high energy conversion efficiency and high sensitivity to the heart movement. The innovative construction of the piezoelectric generator is applied to piezoelectric transformer based on cantilever bending vibrations.