Stimulating Reproductive Organ Patents (Class 607/39)
  • Patent number: 7797049
    Abstract: In general, the invention provides a transurethral ablation device comprising an electrode for delivery of neurostimulation therapy to a patient to prevent or alleviate pain experienced during the course of a transurethral ablation procedure. The device may include a conductive ablation needle that delivers electrical current for ablation of prostate tissue, as well as neurostimulation current to prevent or alleviate pain encountered in response to the ablation current. In this sense, the ablation needle is integrated with a neurostimulation electrode. Alternatively, the device may incorporate a dedicated neurostimulation electrode independently of the ablation needle, either on the needle or on a catheter body that carries the needle.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: September 14, 2010
    Assignee: Medtronic, Inc.
    Inventors: Mark A. Christopherson, John M. Swoyer
  • Patent number: 7763034
    Abstract: The disclosure is directed to a method and tool for implanting a stimulation lead or other medical device adjacent a pudendal nerve. The tool includes a shaped needle that enters a patient and passes through an obturator foramen passage in a pelvis. A physician places a tip of the tool at the pudendal nerve and performs test stimulation to confirm an effective stimulation location. A shape memory cannula initially covering the needle remains at the pudendal nerve when the physician removes the tool. The cannula deforms to follow the curve of the pudendal nerve once the needle is removed, and a lead is inserted into the cannula and secured at the pudendal nerve placement site. This method may provide an easier and more consistent procedure for implanting the stimulation lead near the pudendal nerve.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: July 27, 2010
    Assignee: Medtronic, Inc.
    Inventors: Steven W. Siegel, Eric H. Bonde, Martin T. Gerber
  • Publication number: 20100174137
    Abstract: The present invention generally relates to systems capable of providing and delivering electric potential to a pelvic (i.e., vaginal) structure of a female to cause contraction of pelvic muscles and/or stimulation of pelvic nerves. More particularly, the present invention relates to various systems which include various power members and electrode members, where such power members are capable of providing electric power for such potential from various sources and where such electrode members are capable of delivering the potential along a preset direction or multiple directions. Therefore, such systems may also induce contraction of the pelvic muscles and/or stimulation of the pelvic nerves in a desirable order. Such systems may further induce the muscle contraction and/or nerve stimulation in synchronization with dynamic patterns of various variables of the system.
    Type: Application
    Filed: January 6, 2009
    Publication date: July 8, 2010
    Inventor: Youngtack Shim
  • Patent number: 7734355
    Abstract: Apparatus (18) for treating a condition of a subject is provided. An electrode device (100) is adapted to be coupled to longitudinal nervous tissue (40) of the subject, and a control unit (50) is adapted to drive the electrode device to apply to the nervous tissue a current which is capable of inducing action potentials that propagate in the nervous tissue in a first direction, so as to treat the condition. The control unit is further adapted to suppress action potentials from propagating in the nervous tissue in a second direction opposite to the first direction.
    Type: Grant
    Filed: January 23, 2002
    Date of Patent: June 8, 2010
    Assignee: Bio Control Medical (B.C.M.) Ltd.
    Inventors: Ehud Cohen, Yossi Gross, Shai Ayal
  • Publication number: 20100094372
    Abstract: Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses—e.g., maintain continence and/or produce micturition, and/or provide male/female sexuality responses, and/or provide bowel responses. The systems and methods use a multiple electrode array, or individual electrodes, placed on, in, or near the pudendal nerve. The electrode array, or individual electrodes, in association with a pulse generator, provide selective stimulation of individual fascicles within the pudendal nerve, to achieve different physiologic responses.
    Type: Application
    Filed: October 15, 2009
    Publication date: April 15, 2010
    Inventors: Warren M. GRILL, Kenneth J. GUSTAFSON, Graham H. CREASEY
  • Patent number: 7676269
    Abstract: Methods are provided for treating a subject for a fertility condition. In accordance with the subject methods, at least a portion of a subject's autonomic nervous system is modulated to increase the sympathetic activity/parasympathetic activity ratio in a manner that is effective to treat the subject for the condition. Embodiments of the subject invention include modulating a subject's autonomic nervous system using electrical energy and/or one or more pharmacological agents. The subject methods find use in the treatment of a variety of different fertility conditions. Also provided are kits for use in practicing the subject methods.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: March 9, 2010
    Assignee: Palo Alto Investors
    Inventors: Anthony Joonkyoo Yun, Patrick Yuarn-Bor Lee
  • Patent number: 7660631
    Abstract: Systems and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to tissue affecting the penis to treat erectile dysfunction (for instance, following prostate surgery) uses at least one implantable system control unit (SCU) producing electrical pulses delivered via electrodes and/or producing drug infusion pulses, wherein the stimulating drug(s) are delivered via one or more pumps and infusion outlets.
    Type: Grant
    Filed: April 22, 2005
    Date of Patent: February 9, 2010
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Todd K Whitehurst, James P McGivern
  • Publication number: 20100016657
    Abstract: The present invention relates to an apparatus and method for treating erectile dysfunction. One of the causes of erectile dysfunction is venous leakage, where one or more veins carrying the blood from the penis are unable to retain sufficient blood within the penis to maintain erection. Embodiments of the present invention propose implanting contractile tissue sphincters around the base of the penis and/or around one or more veins, and stimulating the contractile tissue to contract when an erection is required to be maintained. Stimulation is provided by an implantable stimulator.
    Type: Application
    Filed: April 24, 2007
    Publication date: January 21, 2010
    Applicant: Continence Control Systems International Pty Ltd
    Inventors: Peter Robertson, Anthony Clyde Neason Stephen
  • Patent number: 7647112
    Abstract: Devices and methods are provided for electrically stimulating a predetermined body part of a mammal. The method includes placing at least one electrode in proximity to the mammal's skin, injecting an electrically conductive gel into the body of the mammal so as to form a conductive gel pathway extending at least partially along a distance between the at least one electrode and the predetermined body part, and stimulating the predetermined body part by applying an electrical signal via the electrode that travels, at least in part, through the conductive gel pathway.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: January 12, 2010
    Assignee: Ethicon, Inc.
    Inventors: Michael R. Tracey, Anthony DiUbaldi, Douglas B. Johns
  • Patent number: 7627383
    Abstract: Exemplary implantable stimulators for stimulating a stimulation site within a patient include an electronic module configured to generate stimulation and a housing configured to house the electronic module. The housing has a shape allowing the a stimulator and a surgical device to be accommodated together within an insertion tool used to insert the stimulator into the patient. Exemplary methods of stimulating a stimulation site within a patient include generating stimulation with an electronic module and housing the electronic module in a housing. The housing has a shape allowing the housing and a surgical device to be accommodated together within an insertion tool used to insert the housing into the patient.
    Type: Grant
    Filed: March 15, 2005
    Date of Patent: December 1, 2009
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Matthew I. Haller, Jay Daulton, Todd K. Whitehurst, Rafael Carbunaru
  • Patent number: 7623924
    Abstract: Methods and devices for electrically stimulating nerves and organs to induce and modulate the production of hormones according to desired hormone production patterns and hormone level patterns to treat gynecological conditions. Such methods and devices may be used to treat or alleviate the symptoms of menopause. In addition, such methods and devices may be used for birth control.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: November 24, 2009
    Assignee: Leptos Biomedical, Inc.
    Inventor: Hugh Louis Narciso, Jr.
  • Patent number: 7623923
    Abstract: The disclosure describes a tube pressure sensor to measure penile tumescence which may be used in a therapeutic penile tumescence control system. The system senses penile pressure and sends the information to a stimulator that is capable of stimulation therapy to control an erectile state, thus treating sexual dysfunction or, more specifically, erectile dysfunction. Measuring penile tumescence pressure is accomplished through the use of a tube placed within the urethra of the penis and attached to a module implanted within the bladder. Pressure on the tube generates an electrical signal that is sent wirelessly to an implanted stimulator connected to a lead positioned near pelvic floor nerves that stimulate erections. An external device may be used to wirelessly send information to the implanted stimulator to start or stop stimulation in order for the patient to conduct normal sexual activity.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: November 24, 2009
    Assignee: Medtronic, Inc.
    Inventors: Martin T. Gerber, Keith A. Miesel
  • Patent number: 7623925
    Abstract: Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses—e.g., maintain continence and/or produce micturition, and/or provide male/female sexuality responses, and/or provide bowel responses. The systems and methods use a multiple electrode array, or individual electrodes, placed on, in, or near the pudendal nerve. The electrode array, or individual electrodes, in association with a pulse generator, provide selective stimulation of individual fascicles within the pudendal nerve, to achieve different physiologic responses.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: November 24, 2009
    Assignee: Case Western Reserve University
    Inventors: Warren M Grill, Kenneth J Gustafson, Graham H Creasey
  • Publication number: 20090259095
    Abstract: A device for treating hypo-orgasmia or anorgasmia is described. Energy transfer leads that transfer energy may be implanted proximate to one or more of the dorsal nerves of the clitoris in a female. A signal generator may be used to receive a signal (such as a signal from a handheld remote) to begin the transfer of energy via the two energy transfer leads. The signal generator may then generate pulses either in a predetermined manner or a dynamic manner.
    Type: Application
    Filed: November 12, 2008
    Publication date: October 15, 2009
    Inventors: Nicholas Sieveking, Michael Stephanides, Carl Zimmerman
  • Publication number: 20090250068
    Abstract: There is provided a method for controlling a flow of fluid in the vas deferens in order to obtain a controlled male contraception. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow vas deferens, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the vas deferens. The method can be used for restricting or stopping the flow in the vas deferens, or for actively moving the fluid in the vas deferens, with a low risk of injuring the organ.
    Type: Application
    Filed: October 14, 2008
    Publication date: October 8, 2009
    Inventor: Peter Forsell
  • Publication number: 20090247818
    Abstract: There is provided a method for treating sexual dysfunction of a female patient comprising stimulating at least one portion of the patient's female erectile tissue to at least restrict the blood flow leaving the erectile tissue to obtain engorgement with blood of the female erectile tissue. To improve the erection effect the method further comprises gently constricting the erectile portion to restrict the venous blood flow in the erectile portion, and then stimulating the constricted erectile portion to cause contraction of the erectile portion to at least further restrict the blood flow leaving the erectile tissue to obtain engorgement with blood of the female erectile tissue.
    Type: Application
    Filed: October 14, 2008
    Publication date: October 1, 2009
    Applicant: Milux Holding S.A.
    Inventor: Peter Forsell
  • Publication number: 20090248109
    Abstract: There is provided a method for treating a male impotent patient comprising stimulating at least one portion of the patient's normal penile tissue or the prolongation thereof to at least restrict the blood flow leaving the penis to achieve erection. To improve the erection effect the method further comprises gently constricting the penile portion or the prolongation thereof to restrict the venous blood flow in the penile portion, and then stimulating the constricted penile portion to cause contraction of the penile portion to at least further restrict the blood flow leaving the penis to achieve erection.
    Type: Application
    Filed: October 14, 2008
    Publication date: October 1, 2009
    Applicant: Milux Holding S.A.
    Inventor: Peter Forsell
  • Patent number: 7577476
    Abstract: A system and method are provided for transducing vaginal conditions, affecting vaginal or body conditions, and/or stimulating perineal musculature and nerves. A separate, portable, non-implanted intravaginally containable combination probe and transceiver is provided that can sense vaginal conditions, can deliver signals or medication, and/or can stimulate perineal musculature and nerves. This probe unit is provided with 2-way wireless communication for transmitting information that is transduced and for receiving control and programming signals. In addition, a separate combination controller and transceiver is provided for wirelessly sending signals to the probe unit and for receiving signals therefrom. A real time wireless signal feedback loop is thus provided between the controller and the probe and/or external devices, networks and databases.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: August 18, 2009
    Assignee: Athena Feminine Technologies, Inc
    Inventors: Joel S. Hochman, George Sarkis
  • Patent number: 7561918
    Abstract: A method (and associated apparatus) of providing electrical neurostimulation therapy to a patient using an implanted neurostimulator comprises (a) delivering an electrical stimulation to a nerve and (b) determining whether a predetermined condition has occurred as a result of the stimulation. The method further comprises (c) if the predetermined condition has not occurred, adjusting one or more stimulation parameters; and (d) repeating (a), (b), and (c) until the predetermined condition occurs.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: July 14, 2009
    Assignee: Cyberonics, Inc.
    Inventors: Randolph K. Armstrong, Scott A. Armstrong
  • Publication number: 20090036945
    Abstract: Methods and apparatus are therefore provided herein for stimulating a desired physiological effect. The methods and apparatus can be used to control micturition, defecation and/or ejaculation. The methods and apparatus also can be used to control pain in the lower pelvic region, for example and without limitation, interstitial cystitis. The methods and apparatus also can be used to increase sexual sensation.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 5, 2009
    Inventors: Michael B. Chancellor, Changfeng Tai
  • Publication number: 20090018620
    Abstract: The present invention relates to a method for eliciting ejaculation in a male individual, comprising delivering one or more stimulation pulses to lumbar spinothalamic (LSt) cells.
    Type: Application
    Filed: October 9, 2007
    Publication date: January 15, 2009
    Applicant: PELVIPHARM
    Inventors: Jacques Bernabe, Aren Borgdorff, Francois Giuliano
  • Publication number: 20080287733
    Abstract: An apparatus for sexual stimulation in a safe and convenient manner is disclosed. The present invention provides for the in-out motion of an attachment that simulates a penis. The present invention also provides for a vibration mechanism to vibrate the attachment during use. The stroke rate is adjustable by the user. Furthermore, the vibration frequency, and stroke depth are also adjustable by the user during use. The present invention makes use of a mechanical articulating joint, generically known as a spherical rod end or Heim joint for the mounting of an attachment.
    Type: Application
    Filed: May 14, 2007
    Publication date: November 20, 2008
    Inventor: Donald F. Robinson
  • Patent number: 7437194
    Abstract: The invention is directed to techniques for providing electrical stimulation to the prostate gland of a patient. In particular, various techniques are described for providing such stimulation in order to treat sexual dysfunction, benign prostatic hyperplasia (BPH), or other disorders. In some embodiments, the stimulation may be provided to the prostate gland to cause erection or ejaculation in order to treat various sexual dysfunctions. In other embodiments, the stimulation may comprise a training sequence of pulses selected to train and modify the cellular structure of the prostate gland in order to treat BPH or similar prostate disorders.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: October 14, 2008
    Assignee: Medtronic, Inc.
    Inventors: Thomas R. Skwarek, Martin T. Gerber
  • Publication number: 20080183236
    Abstract: Described are implantable devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of tissue volumes at two or more locations adjacent sacral nerves or portions thereof, and/or pudendal nerves or portions thereof. Two or more electrical stimulation regimes are applied on a continuous, alternating, intermittent or other basis to the respective tissue volumes in an amount and manner effective to treat a number of disorders, including, but not limited to, urinary and/or fecal voiding dysfunctions such as constipation, incontinence disorders such as urge frequency and urinary retention disorders, sexual dysfunctions such as orgasmic and erectile dysfunction, pelvic pain, prostatitis, prostatalgia and prostatodynia.
    Type: Application
    Filed: March 31, 2008
    Publication date: July 31, 2008
    Applicant: Medtronic, Inc.
    Inventor: Martin T. Gerber
  • Publication number: 20080161874
    Abstract: Systems and methods screen and/or treat disorders of the body using neurostimulation. A trial system implants a temporary or permanent percutaneous lead and couples the lead to an external pulse generator. The external pulse generator supplies a prescribed stimulation regime through the lead to a targeted tissue region. If an improvement in the treated disorder is achieved, use of the trial system may be continued, or an implantable system may be implanted.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 3, 2008
    Inventors: Maria E. Bennett, Julie Grill, Tina E. Lechman, Joseph J. Mrva, Robert B. Strother, Geoffrey B. Thrope, Therese M. Zmina, Steven M. Galecki, Danny R. Pack
  • Patent number: 7369894
    Abstract: Described are implantable devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of tissue volumes at two or more locations adjacent sacral nerves or portions thereof, and/or pudendal nerves of portions thereof. Two or more electrical stimulation regimes are applied on a continuous, alternating, intermittent or other basis to the respective tissue volumes in an amount and manner effective to treat a number of disorders, including, but not limited to, urinary and/or fecal voiding dysfurictions such as constipation, incontinence disorders such as urge frequency and urinary retention disorders, sexual dysfunctions such as orgasmic and erectile dysfunction, pelvic pain, prostatitis, prostatalgia and prostatodynia.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: May 6, 2008
    Assignee: Medtronic, Inc.
    Inventor: Martin T. Gerber
  • Publication number: 20080103544
    Abstract: A method for treating female sexual dysfunction by subcutaneous electrical stimulation of a peripheral nerve innervating at least a portion of the vulva is disclosed. A lead is placed subcutaneously over a peripheral nerve that innervates at least a portion of the vulva and clitoris. The peripheral nerve is electrically stimulated to cause paresthesia. The method encompasses subcutaneous placement of an electrical lead near any peripheral nerve innervating at least a portion of the vulva and subsequent electrical stimulation of the nerve to cause paresthesia. Further, a method for treating intractable pain of the vulva using percutaneous and subcutaneous peripheral nerve electrostimulation techniques is disclosed.
    Type: Application
    Filed: October 28, 2006
    Publication date: May 1, 2008
    Inventor: Richard L. Weiner
  • Patent number: 7343202
    Abstract: Systems and methods provide a stimulation electrode assembly comprising an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at least one expandable anchoring structure deployable from the lead to engage adipose tissue and resist dislodgment and/or migration of the electrically conductive portion within the adipose tissue region.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: March 11, 2008
    Assignee: NDI Medical, LLC.
    Inventors: Joseph J. Mrva, Robert B. Strother, Geoffrey B. Thrope, Julie Grill, Maria Bennett
  • Patent number: 7330762
    Abstract: A method and system for providing pulse electrical stimulation to at least one of sacral plexus or its branches or portions, inferior hypogastric plexus or its branches or portions, superior hypogastric plexus or its branches or portions in a patient, to provide therapy for one of erectile/sexual dysfunction, prostatitis, pelvic pain, and pain originating from prostatitis pathology. The stimulation system comprises both implanted and external components.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: February 12, 2008
    Assignee: Neuro and Cardiac Technologies, LLC
    Inventors: Birinder R. Boveja, Angely Widhany
  • Patent number: 7328068
    Abstract: Described are implantable devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of the pudendal or other nerves, and optional means for delivering drugs in association therewith. A method of precisely positioning and implanting a medical electrical lead so as to provide optimal stimulation of the pudendal nerve or a portion thereof is also described. Placement of a stimulation lead next to or on the pudendal nerve may be performed using conventional prior art techniques through gross anatomical positioning, but usually does not result in truly optimal lead placement. One method of the present invention utilizes neurophysiological monitoring to assess the evoked responses of the pudendal nerve, and thereby provide a method for determining the optimal stimulation site.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: February 5, 2008
    Assignee: Medtronic, Inc.
    Inventors: Michele Spinelli, Sylvia Malaguti, Martin T. Gerber, Gianluca Giardiello
  • Patent number: 7328069
    Abstract: Described are devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of the pudendal nerves, and means for delivering one or more drugs in association with such electrical stimulation therapies. One or more electrical stimulation signals are applied, and one or more drugs are infused, injected or otherwise administered, to appropriate portions of a patient's pelvic floor and the pudendal nerves or portions thereof in an amount and manner effective to treat a number of disorders, including, but not limited to, urinary voiding dysfunction, fecal voiding dysfunction, constipation, stress incontinence, urge incontinence, urinary retention disorder, sexual dysfunction, orgasmic dysfunction, erectile dysfunction, pelvic pain, prostatitis, prostatalgia and prostatodynia.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: February 5, 2008
    Assignee: Medtronic, Inc.
    Inventor: Martin T. Gerber
  • Patent number: 7203548
    Abstract: Methods of using unidirectionally propagating action potentials (UPAPs) for cavernous nerve stimulation and for certain disorders are provided. Stimulators capable of creating such UPAPs include, but are not limited to, miniature implantable stimulators (i.e., microstimulators), possibly with programmably configurable electrodes. In one aspect, a method includes providing at least one implantable stimulator with at least two electrodes, disposing the electrodes to apply stimulation that unidirectionally propagates action potentials along a cavernous nerve; and applying the stimulation to the cavernous nerve, thereby treating erectile dysfunction while limiting side effects of bidirectional stimulation.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: April 10, 2007
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K Whitehurst, James P McGivern, Rafael Carbunaru, Matthew I Haller, Tom Xiaohai He, Kerry Bradley
  • Patent number: 7177703
    Abstract: A method and system for providing electrical pulses for neuromodulating sacral nerves of a patient utilizing an implantable stimulator. The implantable stimulator comprising a pulse generator module and a stimulus receiver module for coupling with an external stimulator. Control circuitry ensures selective operation of one pulse generator module. The external stimulator comprises a telemetry module for remotely activating (or de-activating) programs over the internet, to arrive at the optimal program for each patient. Once the optimal “dose” is titrated using the external stimulator, the implanted pulse generator can then be programmed to such parameters. The external stimulator in conjunction with the implanted stimulus receiver can override the implanted pulse generator, to provide extra dose of therapy or to conserve the implanted battery. The external stimulator is also networked to other computers.
    Type: Grant
    Filed: May 11, 2003
    Date of Patent: February 13, 2007
    Inventors: Birinder R. Boveja, Angely Widhany
  • Patent number: 7155285
    Abstract: Alpha rhythm brain waves are related to mental and physical relaxation and healing. Based on the studies of bionics, this invention relates to inducing oscillatory alpha rhythm to the human body, and relates to the means of the alpha rhythm machine applied to human body. Research of the alpha rhythm of human brain wave patterns and EEG has indicated special recorded data of alpha rhythm brain waveform which is the bearing of the proper biological information of relaxing and healing. The apparatus was developed and built to construct and release the simulated human brain alpha rhythm signals which are at the frequencies ranging 8 Hz–14 Hz and at the amplitudes altered in high or low. Both the frequencies and the amplitudes are changing at a non-stationary random order in the duration of the event, respectively.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: December 26, 2006
    Inventors: Xiaoming Wang, Huijian Zou, Wei Chen
  • Patent number: 7127287
    Abstract: A multi-purpose, functional electrical stimulation (FES) system 10 includes an implantable stimulator unit 12 for stimulating a plurality of different sites in a patient's body 14. A transmitter 20 is arranged externally of the patient's body 14 for supplying signals transcutaneously to the stimulator unit 12. A controller 16 is in communication with the transmitter 20. At least one implantable switching node 26 has an input terminal 30 in electrical communication with the stimulator unit 12 and a plurality of output terminals to each of which one of a further switching node 26 and a stimulating element 24 is connected. The switching node 26 including addressing circuitry 44 for switching at least one output terminal into electrical connection with the input terminal 30 of the switching node 26 in response to a control signal received from the controller 16 via the stimulator unit 12.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: October 24, 2006
    Assignee: Neopraxis Pty Limited
    Inventors: Michael Duncan, Ian Bruinsma, Zoran Milijasevic, Andrew Barriskill
  • Patent number: 7120497
    Abstract: A method of promoting the healing of a lesion in a smooth muscle, comprising selecting a smooth muscle portion having a lesion and applying a non-excitatory electrical field to the portion, which field reduces the mechanical activity of the portion.
    Type: Grant
    Filed: October 29, 2002
    Date of Patent: October 10, 2006
    Assignee: Metacure NV
    Inventors: Shlomo Ben-Haim, Nissim Darvish, Yuval Mika, Maier Fenster, Bella Felzen, Isaac Shemer
  • Patent number: 7047078
    Abstract: Systems and methods control physiological functions of the urinary tract using at least one electrode sized and configured to be located on, in, or near a targeted component of the pudendal nerve. The systems and methods apply an electrical signal to the electrode at a selected frequency to stimulate the targeted component. The selected frequency is a first frequency or range of frequencies for achieving a first physiologic response (e.g., controlling urinary continence) and a second frequency or range of frequencies, different than the first frequency, for achieving a second physiologic response different than the first physiologic response (e.g., controlling micturition).
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: May 16, 2006
    Assignee: Case Western Reserve University
    Inventors: Joseph W. Boggs, II, Brian J. Wenzel, Kenneth J. Gustafson, Warren M. Grill
  • Patent number: 7006870
    Abstract: An implantable stimulator(s) with at least one infusion outlet and/or at least one electrode, is implanted with the outlet(s) and/or electrode(s) located adjacent to a pudendal nerve(s) and potentially other nerve(s) innervating the reproductive organs, such as the cavernous nerve(s). Stimulation of such nerve(s) is provided via stimulating drugs and/or electrical stimulation as a therapy for erectile dysfunction. The stimulator uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a battery is accomplished, for example, by inductive coupling with an external appliance. The stimulator provides means of stimulating a nerve(s) when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power. The system is capable of open- and closed-loop operation.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: February 28, 2006
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K. Whitehurst, James P. McGivern
  • Patent number: 6993390
    Abstract: An implantable device and method for managing a patient's erectile dysfunction, wherein the device generally comprises: at least one power source member that is adapted to be implanted in the patient's lower abdominal wall; at least one pulse generating member that is adapted to be implanted in the patient's lower abdominal wall; and at least one electrode that is adapted to be implanted at the suprapubic level of the patient's neurovascular bundle of the phallus, is connected to said power source member and pulse generating member, and is adapted to electrically stimulate the neurovascular bundle upon selective activation by the patient.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: January 31, 2006
    Inventor: Stephen M. Zappala
  • Patent number: 6941171
    Abstract: A method and system for treatment of incontinence, urgency, frequency, and/or pelvic pain includes implantation of electrodes on a lead or the discharge portion of a catheter adjacent the perineal nerve(s) or tissue(s) to be stimulated. Stimulation pulses, either electrical or drug infusion pulses, are supplied by a stimulator implanted remotely, and through the lead or catheter, which is tunneled subcutaneously between the stimulator and stimulation site. For instance, the system and method reduce or eliminate the incidence of unintentional episodes of bladder emptying by stimulating nerve pathways that diminish involuntary bladder contractions, improve closure of the bladder outlet, and/or improve the long-term health of the urinary system by increasing bladder capacity and period between emptying.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: September 6, 2005
    Assignee: Advanced Bionics Corporation
    Inventors: Carla M. Mann, Todd K. Whitehurst, James P. McGivern, Gerald E. Loeb, Frances J. R. Richmond
  • Patent number: 6915165
    Abstract: An intestine dysfunction treatment apparatus comprises an electric stimulation device (56) implanted in a patient, who suffers from intestine dysfunction. The stimulation device comprises electric conductors adapted to directly engage with a muscle that directly or indirectly affects the transportation of the content of the patient's intestines, for example the anal sphincter (58) or a portion of the muscle that contracts the bowels, to electrically stimulate the muscle to increase the tonus thereof. A control device (62) is provided for controlling a source of energy (64), which may or may not be implanted, to release electric energy for use in connection with the power of the stimulation device. The apparatus can be used for treating patients suffering from anal incontinence or constipation.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: July 5, 2005
    Assignee: Obtech Medical AG
    Inventor: Peter Forsell
  • Patent number: 6907293
    Abstract: Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses—e.g., maintain continence and/or produce micturition, and/or provide male/female sexuality responses, and/or provide bowel responses. The systems and methods use a multiple electrode array, or individual electrodes, placed on, in, or near the pudendal nerve. The electrode array, or individual electrodes, in association with a pulse generator, provide selective stimulation of individual fascicles within the pudendal nerve, to achieve different physiologic responses.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: June 14, 2005
    Assignee: Case Western Reserve University
    Inventors: Warren M. Grill, Kenneth J. Gustafson, Graham H. Creasey
  • Patent number: 6901294
    Abstract: A small implantable stimulator(s) includes at least two electrodes for delivering electrical stimulation to surrounding tissue. The small stimulator provides means of stimulating the prostate with direct electrical current, such as relatively low-level direct current, without the need for external appliances during the stimulation session. The stimulator may be configured to be small enough to be implanted entirely within the prostate. Open- and closed-loop systems are disclosed.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: May 31, 2005
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K. Whitehurst, James P. McGivern, Janusz A. Kuzma
  • Patent number: 6885895
    Abstract: Systems and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to tissue affecting the penis to treat erectile dysfunction (for instance, following prostate surgery) uses at least one implantable system control unit (SCU) producing electrical pulses delivered via electrodes and/or producing drug infusion pulses, wherein the stimulating drug(s) are delivered via one or more pumps and infusion outlets.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: April 26, 2005
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K. Whitehurst, James P. McGivern
  • Patent number: 6879858
    Abstract: A system and method for detecting for and initiating contractions of a uterus of a human patient employs a sensor for sensing electrical activity of the uterus of the patient. Data from the sensed electrical activity is stored in memory. A processor accesses the stored data for analysis. Electrical energy is applied to the uterus to initiate a uterine contraction when the analyzed data fails to satisfy predetermined detection criteria.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: April 12, 2005
    Assignee: Reproductive Health Technologies, Inc.
    Inventor: John M. Adams
  • Patent number: 6862479
    Abstract: One or more implantable system control units (SCU) apply one or more stimulating drugs and/or electrical pulses to a spinal section responsible for innervating the male reproductive organs. The SCU uses a power source/storage device, such as a rechargeable battery. If necessary, periodic recharging of such a battery is accomplished, for example, by inductive coupling with an external appliance. The SCU provides means of stimulating a tissue(s) with electrical and/or infusion pulses when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the SCU(s) and/or for the transmission of power. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one implant includes a sensor, and the sensed condition is used to adjust stimulation parameters.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: March 1, 2005
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K. Whitehurst, James P. McGivern
  • Publication number: 20040215237
    Abstract: In general, the invention provides a transurethral ablation device comprising an electrode for delivery of neurostimulation therapy to a patient to prevent or alleviate pain experienced during the course of a transurethral ablation procedure. The device may include a conductive ablation needle that delivers electrical current for ablation of prostate tissue, as well as neurostimulation current to prevent or alleviate pain encountered in response to the ablation current. In this sense, the ablation needle is integrated with a neurostimulation electrode. Alternatively, the device may incorporate a dedicated neurostimulation electrode independently of the ablation needle, either on the needle or on a catheter body that carries the needle.
    Type: Application
    Filed: April 25, 2003
    Publication date: October 28, 2004
    Applicant: Medtronic, Inc.
    Inventors: Mark A. Christopherson, John M. Swoyer
  • Publication number: 20040193228
    Abstract: Described are implantable devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of the pudendal and sacral nerves, or portions thereof, and optional means for delivering drugs in association therewith. Two or more electrical stimulation regimes are applied on a continuous, alternating, intermittent or other basis to the sacral and pudendal nerves, and optionally one or more drugs are infused, injected or otherwise administered, to appropriate portions of a patient's pelvic floor and pudendal nerve and/or sacral nerve, or portions thereof, in an amount and manner effective to treat a number of disorders, including, but not limited to, urinary and/or fecal voiding dysfunctions such as constipation, incontinence disorders such as urge frequency and urinary retention disorders, sexual dysfunctions such as orgasmic and erectile dysfunction, pelvic pain, prostatitis, prostatalgia and prostatodynia.
    Type: Application
    Filed: December 23, 2003
    Publication date: September 30, 2004
    Inventor: Martin T. Gerber
  • Publication number: 20040181261
    Abstract: Cavernous nerve stimulation is induced by means of a device which creates a time varying magnetic field which, in turn, creates an electric field in a direction parallel to the nerve and at the nerve so as to cause depolarization leading to an action potential and subsequent sensory stimulation and erection.
    Type: Application
    Filed: December 16, 2003
    Publication date: September 16, 2004
    Inventor: Joseph Manne
  • Patent number: RE38654
    Abstract: An electro-stimulation device includes a pair of electrodes for connection to at least one location in the body that affects or regulates the heartbeat. The electro-stimulation device both electrically arrests the heartbeat and stimulates the heartbeat. A pair of electrodes are provided for connection to at least one location in the body that affects or regulates the heartbeat. The pair of electrodes may be connected to an intravenous catheter for transvenous stimulation of the appropriate nerve. A first switch is connected between a power supply and the electrodes for selectively supplying current from the power supply to the electrodes to augment any natural stimuli to the heart and thereby stop the heart from beating. A second switch is connected between the power supply and the electrodes for selectively supplying current from the power supply to the electrodes to provide an artificial stimulus to initiate heartbeating.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: November 23, 2004
    Assignee: Medtronic, Inc.
    Inventors: Michael R. S. Hill, Kenneth R. Jonkman