Electrical Treatment Of Pain Patents (Class 607/46)
  • Patent number: 11364381
    Abstract: A method of managing pain related to a peripheral nerve injury of a subject comprises delivering stimulation energy of a first frequency to the target nerve via at least one electrode assembly during a regenerative phase and delivering stimulation energy of a second frequency for a predetermined period via the at least one electrode assembly during at least one neuropathic pain management phase.
    Type: Grant
    Filed: May 31, 2021
    Date of Patent: June 21, 2022
    Assignee: Epineuron Technologies Inc.
    Inventors: Michael Patrick Willand, Sergio David Aguirre
  • Patent number: 11364378
    Abstract: Disclosed herein are circuits and methods for a multi-electrode implantable stimulator device incorporating one decoupling capacitor in the current path established via at least one cathode electrode and at least one anode electrode. In one embodiment, the decoupling capacitor may be hard-wired to a dedicated anode on the device. The cathodes are selectively activatable via stimulation switches. In another embodiment, any of the electrodes on the devices can be selectively activatable as an anode or cathode. In this embodiment, the decoupling capacitor is placed into the current path via selectable anode and cathode stimulation switches. Regardless of the implementation, the techniques allow for the benefits of capacitive decoupling without the need to associate decoupling capacitors with every electrode on the multi-electrode device, which saves space in the body of the device.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: June 21, 2022
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Jordi Parramon, Kiran Nimmagadda, Emanuel Feldman, Yuping He
  • Patent number: 11351447
    Abstract: Systems and methods are disclosed for interacting with a person by rendering images with a display; capturing a vision and transmit a vision to the display; detecting with sensors one or more biometric and physical conditions, the sensor having a wireless transceiver adapted to communicate with a remote processor; and providing sexual stimulation with explicit augmented or virtual reality views of sex organ body part based on the biometric and physical conditions.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: June 7, 2022
    Inventor: Naveen Kumar
  • Patent number: 11351375
    Abstract: Embodiments of the disclosure include systems and method for spinal cord stimulation. A spinal cord stimulator may comprise a pulse generator comprising electronic circuitry configured to generate output current; at least one lead in communication with the generator and configured to extend into the epidural space of a patient's spinal column; at least one electrode contact located proximate to a distal end of the at least one lead and configured to provide electric stimulation to a portion of a patient's spinal cord; and at least one sensor located along the at least one lead configured to determine a distance between the at least one lead and a surface of the patient's spinal cord, wherein the generator receives the determined distance, and wherein the generator is configured to adjust the stimulation provided by the at least one electrode contact based on the determined distance.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: June 7, 2022
    Inventor: John Mansell
  • Patent number: 11338127
    Abstract: A method is disclosed for programming a patient's stimulator device using an external device. The method provides a Graphical User Interface (GUI) on the external device that allows the patient to select from a plurality of displayed stimulation modes to program stimulation provided by one or more electrodes of the stimulator device. The external device stores a model derived for the patient, which model comprises information indicative of a plurality of frequency/pulse width/amplitude coordinates predicted to provide optimal stimulation for the patient. Each stimulation mode corresponds with a subset of coordinates defined in accordance with the plurality of coordinates in the model. Selection of one of the stimulation modes limits programming the stimulator device with coordinates that are within the corresponding subset of coordinates.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: May 24, 2022
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Ismael Huertas Fernandez, Que T. Doan, Changfang Zhu, Rosana Esteller, Michael A. Moffitt
  • Patent number: 11331481
    Abstract: An apparatus for relieving pain in a region of the body of a user by contacting electrodes to a surface of the body of the user at the region and providing a series of electrical impulses to the region, the apparatus including: (a) at least two electrodes adapted to contact a surface of a body of the user; (b) a control unit; and (c) a signal generator, associated with the control unit and responsive thereto, the signal generator and the control unit adapted to operative connect to a power supply, the signal generator adapted, in an operative mode, to provide a series of electrical impulses to the surface of the body, via the electrodes, the series including a plurality of cycles, each of the cycles having a positive voltage pulse and a negative voltage pulse, wherein a frequency of the plurality of cycles is optionally within a range of 60-150 cycles per second, wherein a time-averaged voltage amplitude (Vap) of the positive voltage pulse, over an entire duration (Tppositive) thereof, is 20-90 Volts, and whe
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: May 17, 2022
    Assignee: IPULSE MEDICAL LTD.
    Inventors: Zvi Nachum, Shalom Lampert
  • Patent number: 11311726
    Abstract: An external control device, neuromodulation system, and method of providing therapy to a patient using an implantable neuromodulator implanted within the patient. Electrical modulation energy is delivered from the neuromodulator to the patient in accordance with the pre-existing modulation program when in one of the super-threshold delivery mode and the sub-threshold delivery mode. Operation of the neuromodulator is switched to the other of the super-threshold delivery mode and the sub-threshold delivery mode. A new modulation program may be derived from a pre-existing modulation program, and the neuromodulator may deliver the electrical modulation energy to the patient in accordance with the pre-existing modulation program during the other of the super-threshold delivery mode and the sub-threshold delivery mode.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: April 26, 2022
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Dennis Allen Vansickle, Dongchul Lee, Sridhar Kothandaraman, Que T. Doan, Changfang Zhu, Jordi Parramon, Justin Holley, Bradley L. Hershey, Christopher E. Gillespie, Rafael Carbunaru, Nazim Wahab
  • Patent number: 11298549
    Abstract: A medical device control unit is provided. The control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: April 12, 2022
    Assignee: NYXOAH SA
    Inventors: Adi Mashiach, Itzik Mashiach, Guy Siman
  • Patent number: 11266834
    Abstract: An electro-acupuncture (EA) system and method for performing EA on a patient are provided. The EA system comprises a wearable neurostimulator device, at least a first pair of electrically-conductive acupuncture needles and a system controller. The wearable neurostimulator device comprises a casing, an EA circuit mechanically coupled to the casing, and an attachment device mechanically coupled to the casing and adapted to removably secure the wearable neurostimulator device to the patient. The first pair of electrically-conductive acupuncture needles is mechanically coupled to the casing and electrically coupled to the EA circuit. The system controller is in communication with the EA circuit of the wearable neurostimulator device via a communication link and controls the EA circuit to cause the EA circuit to output an output voltage selected by the system controller at a frequency selected by the system controller.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: March 8, 2022
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Jin-Woo Choi, Jose Aquiles Parodi Amaya, Ronald Koh
  • Patent number: 11260230
    Abstract: An implantable pulse generator (IPG) that generates spinal cord stimulation signals for a human body has a programmable signal generator that can generate the signals based on stored signal parameters without any intervention from a processor that controls the overall operation of the IPG. While the signal generator is generating the signals the processor can be in a standby mode to substantially save battery power. The IPG also contains circuity to indicate to a patient that proper alignment exists between the IPG and an external charger to charge a battery in the IPG.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: March 1, 2022
    Assignee: Cirtec Medical Corporation
    Inventors: Saif Khalil, Raghavendra Angara, Miles Curtis, Christopher Biele, Daniel Fellmeth, Hrishikesh Gadagkar
  • Patent number: 11253705
    Abstract: Stimulation treatments for various medical disorders, such as neurological disorders, comprise novel systems, strategies, and methods for providing TMS, electrical, magnetic, optical and other stimulation modalities. Some stimulation methods comprise varying the stimulation parameters to improve the therapeutic efficacy of stimulation, and decrease risk of habituation and side-effects such as interference with normal brain, sensory, motor, and cognitive processes. The creation, and subsequent variation, of stimulation parameters can use sensed data in order to match, adjust, or avoid matching characteristics of the stimulation therapy relative to certain endogenous brain activities. Improvements for the treatment of pain are disclosed.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: February 22, 2022
    Inventor: Michael Sasha John
  • Patent number: 11235153
    Abstract: A medical device for electrical stimulation of a patient. A pulse generator generates current pulses for the electrical stimulation. An electrode lead with a plurality of electrode contacts delivers the pulses to tissue of the patient. The pulse generator repeatedly delivers a current pulse between two electrodes forming a first group and delivers a charge balancing current pulse after each current pulse between the electrodes of the first group. The respective current pulse is separated from the succeeding charge balancing current pulse by an inter pulse interval. The respective current pulse has an amplitude with the same absolute magnitude as the succeeding charge balancing current pulse, but is of opposite sign. The pulse generator delivers between each current pulse and the succeeding charge balancing current pulse a current pulse between two further electrodes forming a second group of electrode contacts of the plurality of electrode contacts.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: February 1, 2022
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Andrew B. Kibler, Sean Slee, Pamela Shamsie Victoria Riahi
  • Patent number: 11234852
    Abstract: A noxipoint stimulating device uses light, mechanical force, and heat as a source of stimulating energy, which is configured to be applied on the Noxipoints.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: February 1, 2022
    Inventor: Charles C. Koo
  • Patent number: 11229790
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat epileptic seizures by electrical noninvasive stimulation of a vagus nerve. The system comprises a handheld stimulator that is applied to the surface of the patient's neck, wherein the stimulator comprises or is joined to a smartphone. A camera of the smartphone may be used to position and reposition the stimulator to a particular location on the patient's neck. The system may also comprise a base station that is used to meter the charging of a rechargeable battery within the stimulator. The base station and stimulator transmit data to one another regarding the status of a stimulation session.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: January 25, 2022
    Assignee: electroCore, Inc.
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Patent number: 11224750
    Abstract: A neuromodulation system comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes, a user interface configured for receiving input from a user that selects one of a plurality of different shapes of a modulating signal and/or selects one of a plurality of different electrical pulse parameters of an electrical pulse train, neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals, and pulse train modulation circuitry configured for modulating the electrical pulse train in accordance with the selected shape of the modulating signal and/or selected electrical pulse parameter of the electrical pulse train.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: January 18, 2022
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Changfang Zhu
  • Patent number: 11219766
    Abstract: A method of controlling a neural stimulus by use of feedback. The neural stimulus is applied to a neural pathway in order to give rise to an evoked action potential on the neural pathway. The stimulus is defined by at least one stimulus parameter. A neural compound action potential response evoked by the stimulus is measured. From the measured evoked response a feedback variable is derived. A feedback loop is completed by using the feedback variable to control the at least one stimulus parameter value. The feedback loop adaptively compensates for changes in a gain of the feedback loop caused by electrode movement relative to the neural pathway.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: January 11, 2022
    Assignee: Saluda Medical Pty Ltd
    Inventors: Peter Scott Vallack Single, Dean Michael Karantonis
  • Patent number: 11219763
    Abstract: The techniques of the disclosure describe example medical devices, systems, and methods for delivering stimulation therapy comprising a first set of a plurality of pulses having a first amplitude, and a second set of a plurality of pulses having a second amplitude greater than the first amplitude. The second amplitude is adjusted to an adjusted second amplitude based on second amplitude being less than or greater than activation threshold. The first amplitude is adjusted based on adjusted second amplitude, and therapy is delivered based at least one the adjusted first amplitude.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: January 11, 2022
    Assignee: MEDTRONIC, INC.
    Inventor: Nathan A. Torgerson
  • Patent number: 11207520
    Abstract: An example of a system includes a blood pressure modulation device and a controller. The blood pressure modulation device may be configured to deliver a therapy to chronically maintain blood pressure within a prescribed range. The blood pressure modulation device may include a neuromodulator configured to deliver neuromodulation energy to neural tissue in a spinal cord or near the spinal cord using a first parameter set. The controller may include analyzer circuitry configured to determine an actual or anticipated blood pressure demand event indicated for a blood pressure change, and therapy parameter adjuster circuitry configured to respond to the actual or anticipated blood pressure demand event by delivering neuromodulation energy using a second parameter set to change the blood pressure.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: December 28, 2021
    Assignees: Regents of the University of Minnesota, Boston Scientific Scimed, Inc.
    Inventors: Craig Stolen, Bryan Allen Clark, Manda L. Keller-Ross, Ninitha Margret Julfiya Asirvatham-Jeyaraj, Daniel P. Chantigian
  • Patent number: 11207521
    Abstract: A new architecture is disclosed for an IPG having a master and slave electrode driver integrated circuits (ICs). The electrode outputs on the ICs are wired together. Each IC can be programmed to provide pulses with different frequencies. Active timing channels in master and slave ICs are programmed to provide the desired pulses, while shadow timing channels in the master and slave are programmed with the timing data from the active timing channels in the other IC so that each chip knows when the other is providing a pulse, so that each chip can disable its recovery circuitry so as not to defeat those pulses. In the event of pulse overlap at a given electrode, the currents provided by each chip will add at the affected electrode. Compliance voltage generation is dictated by an algorithm to find an optimal compliance voltage even during periods when pulses are overlapping.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: December 28, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Emanuel Feldman, Jordi Parramon, Paul J. Griffith, Jess Shi, Robert Tong, Goran Marnfeldt
  • Patent number: 11202909
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: December 21, 2021
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Patent number: 11198000
    Abstract: A patient treatment unit for delivering non-invasive pulsed energy to living tissue with a probe stimulus generator circuit configured to output, as a treatment signal, a sequence of DC electrical pulses at a controlled pulse frequency of about 20 kHz and having a pulse voltage defined by a variable supply voltage of the probe stimulus generator circuit. The unit includes primary and secondary probes for contacting a body, an intensity adjustment circuit configured to control the variable supply voltage, and an electronic timer display configured to display an elapsed time in decimal numbers in minute and second format. An electrical current of the pulses is in a range of 0.1-2 mA while the probes are contacting the body. An operating output voltage across the probes while conducting the treatment signal does not exceed a maximum operating output voltage of 165 VDC while the probes are contacting the body.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: December 14, 2021
    Assignee: TrueRelief, LLC
    Inventor: John Crosson
  • Patent number: 11191973
    Abstract: An external transmitter apparatus for a transcutaneous energy transfer (TET) system for supplying power for use in energising an implantable medical device is disclosed, the apparatus comprising an external transmitter apparatus comprising a plurality of transmitter coils for delivering power transcutaneously to one of a plurality of receiver coils of an implantable receiver apparatus of the TET system when located in proximity thereto. The external transmitter apparatus is provided with power by a pulsed power supply. The coils of the external transmitter apparatus and the implantable receiver apparatus may be printed on flexible substrates. Also disclosed are methods of operating such a system, an external transmitter apparatus for use in such a system, an external transmitter apparatus and an implantable receiver apparatus including flexible coils.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: December 7, 2021
    Assignee: University of Ulster
    Inventors: Omar Jacinto Escalona, David John McEneaney, James McLaughlin
  • Patent number: 11191974
    Abstract: A capacity-expanding separated interface nerve electrode (SINE) can be used to deliver a nerve conduction block to one or more nerves. The SINE can include a source electrode coupled to a waveform generator. The source electrode can deliver an electrical neuromodulation signal (e.g., a direct current (DC) signal) to an ionically conductive medium. The SINE can also include a vessel holding the ionically conductive medium, which can include a material that facilitates a transformation of the electrical neuromodulation signal to an ionic neuromodulation signal with a high charge capacity. The SINE can also include a nerve interface that can deliver the ionic neuromodulation signal to a nerve. The SINE can be used in combination with a return electrode that is also coupled to the waveform generator.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: December 7, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Tina L. Vrabec, Jesse S. Wainright, Kevin L. Kilgore, Narendra Bhadra, Niloy Bhadra
  • Patent number: 11185706
    Abstract: A connector system is provided for a positional sensitive spinal cord stimulation apparatus using near infrared reflectometry which incorporates the ability to connect to current IPG's either in a percutaneous or laminectomy form and which utilizes a novel light to frequency converter to generate a stimulation voltage in wave form to effect spinal cord stimulation.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: November 30, 2021
    Assignee: WAVEGATE CORPORATON
    Inventor: Erich W. Wolf, II
  • Patent number: 11179567
    Abstract: Systems, devices, and techniques are described for adjusting electrical stimulation based on detected ECAPs. In one example, a medical device includes processing circuitry configured to control stimulation circuitry to deliver a first electrical stimulation pulse and sensing circuitry to detect, after delivery of the first electrical stimulation pulse, an ECAP signal. The processing circuitry may be configured to determine a characteristic value of the ECAP signal, determine an ECAP differential value that indicates whether the characteristic value of the ECAP signal is one of greater than a selected ECAP characteristic value or less than the selected ECAP characteristic value, determine, based on the ECAP differential value, a gain value, determine, based on the gain value, a parameter value that at least partially defines a second electrical stimulation pulse, and control the stimulation circuitry to deliver the second electrical stimulation pulse according to the parameter value.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: November 23, 2021
    Assignee: Medtronic, Inc.
    Inventors: David A. Dinsmoor, Christopher L. Pulliam, Hank Bink, Kristin N. Hageman
  • Patent number: 11173391
    Abstract: A system includes a mobile device having one or more cameras to take images; a sensor detecting reflected light from one or more lasers and a diffuser to detect object range or dimension; code for motion tracking, environmental understanding by detecting planes in an environment, and estimating light and dimensions of the surrounding based on the one or more lasers; code to estimate a three-dimensional (3D) volume of an object from multiple perspectives and from projected laser beams to measure size or scale and determine locations of points on the object's surface in a plane or a slice using time-of-flight, wherein positions and cross-sections for different slices are correlated to construct a 3D model of the object, including object position and shape; the device receiving user request to select a content from one or more augmented, virtual, or extended reality contents and rendering a reality view of the environment.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: November 16, 2021
    Inventor: Naveen Kumar
  • Patent number: 11173520
    Abstract: Aspects of this disclosure relate to driving a capacitive micromachined ultrasonic transducer (CMUT) with a pulse train of unipolar pulses. The CMUT may be electrically excited with a pulse train of unipolar pulses such that the CMUT operates in a continuous wave mode. In some embodiments, the CMUT may have a contoured electrode.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: November 16, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Bo Ma, Kamyar Firouzi, Butrus T. Khuri-Yakub, Jose Joseph
  • Patent number: 11167129
    Abstract: Applying therapeutic neural stimuli involves monitoring for at least one of sensory input and movement of a user. In response to detection of sensory input or user movement, an increased stimulus dosage is delivered within a period of time corresponding to a duration of time for which the detected sensory input or user movement gives rise to masking, the increased stimulus dosage being configured to give rise to increased neural recruitment.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: November 9, 2021
    Assignee: Saluda Medical Pty Ltd
    Inventor: John Louis Parker
  • Patent number: 11160981
    Abstract: A system or method for identifying sets of stimulation parameters can include receiving at least one image of a region of a patient; registering the at least one image with an anatomical or physiological atlas that identifies different anatomical or physiological structures; identifying a desired stimulation region using the at least one image; comparing the desired stimulation region with each of a plurality of predetermined estimated stimulation regions, where each of the estimated stimulation regions is a calculated estimate of a stimulation volume for a corresponding set of electrical stimulation parameters; selecting one of the predetermined estimated stimulation regions based on the comparing; and providing the corresponding set of electrical stimulation parameters for the selected one of the predetermined estimated stimulation regions to a user or an electrical stimulation device.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: November 2, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Stephen Carcieri, G. Karl Steinke, Richard Mustakos
  • Patent number: 11147961
    Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a target nerve within the patient. The electrical signal comprises bursts with a frequency of 1 to 100 Hz. Each of the bursts has 2 to 20 pulses with a duration of about 50 microseconds to about 1000 microseconds.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: October 19, 2021
    Assignee: ELECTROCORE, INC.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 11135436
    Abstract: A pulse generator includes charging circuitry configured to provide electrical power to the pulse generator. The pulse generator includes communication circuitry configured to conduct wireless telecommunications with external programming devices. The telecommunications contain programming instructions sent from the external programming devices. The pulse generator includes stimulation circuitry configured to generate electrical pulses based on the programming instructions. The electrical pulses include a first component that is paresthesia-inducing and a second component that is non-paresthesia-inducing.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: October 5, 2021
    Assignee: CIRTEC MEDICAL CORPORATION
    Inventors: Norbert Kaula, Yohannes Iyassu, Scott Brainard
  • Patent number: 11129989
    Abstract: Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system may be configured to deliver electrical stimulation therapy to a patient, the electrical stimulation therapy comprising a plurality of therapy pulses at a predetermined pulse frequency over a period of time and deliver, over the period of time, a plurality of control pulses interleaved with at least some therapy pulses of the plurality of therapy pulses. The system may also be configured to sense, after one or more control pulses and prior to an immediately subsequent therapy pulse of the plurality of therapy pulses, a respective evoked compound action potential (ECAP), adjust, based on at least one respective ECAP, one or more parameter values that at least partially defines the plurality of therapy pulses, and deliver the electrical stimulation therapy to the patient according to the adjusted one or more parameter values.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: September 28, 2021
    Assignee: Medtronic, Inc.
    Inventors: David A. Dinsmoor, Heather Diane Orser, Scott R. Stanslaski, Erik J. Peterson
  • Patent number: 11129991
    Abstract: Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system may be configured to deliver electrical stimulation therapy to a patient, the electrical stimulation therapy comprising a plurality of therapy pulses at a predetermined pulse frequency over a period of time and deliver, over the period of time, a plurality of control pulses interleaved with at least some therapy pulses of the plurality of therapy pulses. The system may also be configured to sense, after one or more control pulses and prior to an immediately subsequent therapy pulse of the plurality of therapy pulses, a respective evoked compound action potential (ECAP), adjust, based on at least one respective ECAP, one or more parameter values that at least partially defines the plurality of therapy pulses, and deliver the electrical stimulation therapy to the patient according to the adjusted one or more parameter values.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: September 28, 2021
    Assignee: Medtronic, Inc.
    Inventors: David A. Dinsmoor, Kristin N. Hageman, Hank Bink
  • Patent number: 11123563
    Abstract: A system for adjusting neuromodulation parameters used by a neuromodulator operably connected to a plurality of electrodes to modulate a neural target, may comprise a translation trigger detector configured to determine that a translation trigger has occurred, a first parameter setting storage configured to store first parameter settings for use by the neuromodulator to modulate the neural target, and a neuromodulation parameter translator. The neuromodulation parameter translator may be operably connected to the translation trigger detector to automatically translate the first parameter settings into a second parameter settings in response to determining the translation trigger has occurred, and replace the first parameter settings with the second parameter settings, or store the second parameter settings in a second parameter setting storage.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: September 21, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Richard Mustakos, Stephen Carcieri, Chirag Shah, Peter J. Yoo
  • Patent number: 11123545
    Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a target nerve within the patient. The electrical signal comprises bursts of about 2 to about 20 pulses and the pulses oscillate between a positive voltage and a negative voltage within each burst.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: September 21, 2021
    Assignee: ELECTROCORE, INC.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 11116974
    Abstract: A device for neurostimulation includes a pulse generator for generating current having pulses and at least one first pair of electrodes connected to the pulse generator. The device provides a user-programmable therapy strength parameter configuration and at least two current parameter configurations for neurostimulation stored in the pulse generator. The current parameter configurations are controlled by the therapy strength configuration, at least one of the current parameter configurations is associated with a level of paresthesia sensation of a patient and at least one of the current parameter configurations is associated with a paresthesia-free therapy for the patient. The association between therapy strength parameter and current parameter configurations uniquely adjusts the current parameter configurations based on paresthesia or paresthesia-free intent, when neurostimulation is performed using parameter configurations.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: September 14, 2021
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Andrew B. Kibler, Dirk Muessig, Marcelo Baru
  • Patent number: 11116979
    Abstract: A device which includes a generator of electric current pulses and a neurostimulation probe with M sectoral electrodes forming stimulation poles for passing a current between at least one anode and at least one cathode in a predetermined stimulation configuration. The generator includes N current sources and N current sinks, the N sources and the N sinks being defined independently of the M electrodes. A first distribution circuit can indiscriminately and dynamically switch any of the N sources to any of the M electrodes, and a second distribution circuit can indiscriminately and dynamically switch any of the N sinks to any of the M electrodes. The device can thus define a plurality of commutation combinations between sources and/or sinks, providing a single average current in the organ to be stimulated for different respective predetermined pole configurations.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: September 14, 2021
    Assignee: Sorin CRM SAS
    Inventors: Guillaume Chatalic, Marc LaFlutte, Jean-Claude Bierg
  • Patent number: 11116985
    Abstract: A clinician programmer may be coupled with an implantable temporary or permanent lead in a patient. Generally, the clinician programmer may comprise a portable housing, a signal/stimulation generator, and a graphical user interface. The housing has an external surface and encloses circuitry at least partially disposed within the housing. The signal/stimulation generator may be disposed within the housing and configured to deliver test stimulation to a nerve tissue of the patient via the implantable lead. The graphical user interface at least partially comprises the external surface of the housing and has a touch screen display for direct user interaction or for use with a keyboard, mouse, or the like.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: September 14, 2021
    Assignee: AXONICS, INC.
    Inventors: Guangqiang Jiang, John Woock, Dennis Schroeder, Eric Schmid
  • Patent number: 11110277
    Abstract: A non-zero starting value for ramping up a stimulation parameter for an electrical stimulation to be delivered to a patient is determined. The non-zero starting value is customized to the patient. A pulse generator is caused to generate the electrical stimulation, which is delivered to the patient via an implanted lead. The pulse generator is caused to ramp up, from the determined non-zero starting value and toward a predefined maximum limit value, the stimulation parameter for a plurality of electrode contacts on the lead. Feedback is received from the patient in response to the ramping up. The feedback is received via an electronic patient feedback device. Based on the ramping up and the received feedback from the patient, a perception threshold is determined for each of the plurality of electrode contacts. The perception threshold is a value of the stimulation parameter that corresponds to the patient feeling the electrical stimulation.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: September 7, 2021
    Assignee: CIRTEC MEDICAL CORP.
    Inventors: Norbert Kaula, Yohannes Iyassu
  • Patent number: 11103706
    Abstract: A method for enhancing muscle function of skeletal muscles in connection with a planned spine surgery intervention in a patient's back is provided. The method includes implanting one or more electrodes in or adjacent to tissue associated with one or more skeletal muscles within a back of a patient, the one or more electrodes in electrical communication with a pulse generator programmed for enhancing muscle function of the one or more skeletal muscles. Electrical stimulation is delivered, according to the programming during a time period associated with the planned spine surgery intervention, from the pulse generator to the tissue associated with the one or more skeletal muscles via the one or more electrodes, thereby improving neuromuscular control system performance of the one or more spine stabilizing muscles in connection with the planned spine surgery intervention to reduce the patient's recovery time associated with the planned spine surgery intervention.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: August 31, 2021
    Assignee: Mainstay Medical Limited
    Inventors: Dan Sachs, Prashant Brijmohansingh Rawat, Peter Andrew Crosby, Jason Hannon
  • Patent number: 11097102
    Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a vagus nerve. The system comprises a handheld stimulator including a housing having a contact surface for contacting an outer skin surface of a patient. The housing is configured for attachment and electrical coupling to a mobile device configured to receive a wireless signal. An energy source is coupled to the stimulator and the mobile device. The energy source is configured to generate an electric field that transmits an electric current through the contact surface and the outer skin surface to modulate a nerve within the patient and thereby treat a medical condition of the patient.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: August 24, 2021
    Assignee: ELECTROCORE, INC.
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Patent number: 11083896
    Abstract: In some examples, a medical device is configured to deliver high dose electrical stimulation therapy to a patient by at least generating and delivering an electrical stimulation signal having a relatively high duty cycle, and a stimulation intensity less than a perception or paresthesia threshold intensity level for the patient. The pulses may each have a relatively low amplitude, but due at least in part to a relatively high number of pulses per unit of time, the electrical stimulation signal may be high enough to elicit a therapeutic response from the patient. In some examples, the plurality of pulses may have a duty cycle in a range of about 5% to about 50%. Following the generation and delivery of the plurality of pulses, one or more recharge pulses for the plurality of pulses may be delivered.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: August 10, 2021
    Assignee: Medtronic, Inc.
    Inventor: Lisa M. Johanek
  • Patent number: 11071864
    Abstract: An apparatus and method for providing split stimulation currents in a pulse generator. In one embodiment, a current regulator of the pulse generator includes a digitally-programmable analog voltage generator coupled to a first input of an error amplifier that receives a second input controlled by a programmable resistor network configured to control a programmable total stimulation current output. A plurality of current splitting switches are operative to split the programmable total stimulation current output into a corresponding plurality of split current segments, which may be individually mapped to a selected set of lead electrodes across one or more implantable leads associated with the pulse generator.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: July 27, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Steven Boor, Daran DeShazo
  • Patent number: 11071863
    Abstract: The techniques described herein are example medical devices, systems, and methods for sensing evoked potentials in a tissue of the patient, and, based on the sensed evoked potentials, adjusting one or more parameters defining the electrical stimulation therapy delivered to the patient. In one example, a system controls delivery of an electrical stimulation therapy from an implantable medical device to a patient according to at least one therapy program, wherein the electrical stimulation therapy is configured to provide pain relief to the patient without substantially resulting in paresthesia perceived by the patient.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: July 27, 2021
    Assignee: Medtronic, Inc.
    Inventor: Nathan A. Torgerson
  • Patent number: 11065447
    Abstract: Devices and methods to deliver microcurrent stimulation therapy to the human body, when connected to a micro-stimulation current-generating apparatus. The method of applying microcurrent stimulation therapy to key points around the eye for treatment of problems such as macular degeneration, retinitis pigmentosa, glaucoma, optic neuritis and other eye-related or nerve-related conditions, as well as other diseases, such as Bell's Palsy, requiring localized stimulation to the eyes and/or on other body parts.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: July 20, 2021
    Assignee: i-Lumen Scientific, Inc.
    Inventors: Blair P. Mowery, Marshall T. Masko, John B. Jarding, Gary A. Tapp
  • Patent number: 11065450
    Abstract: A neuromodulation system and method with feedback optimized electrical field generation for stimulating target tissue of a patient to treat neurological and non-neurological conditions. The system generally includes implantable electrodes, implantable sensors, an implantable or external electrical signal generator, and an implantable or external controller. The controller controls the electrical signal generator to generate electrical noise stimulation signals that are delivered to the target tissue via the electrodes and that produce an optimized electric field having maximized voltage with low current density. The sensors produce temperature and impedance data for the target tissue and the controller automatically responds to values of the sensor data that indicate potential damage to the target tissue to reduce the strength of the electric field.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: July 20, 2021
    Assignee: Soin Neuroscience, LLC
    Inventor: Amol N. Soin
  • Patent number: 11052251
    Abstract: A device for the transcutaneous electrical stimulation of the trigeminal nerve is provided. The device has an elongated symmetrical support with at least one electrode pair, and the support can be applied on a person's forehead in the supraorbital region to cover the afferent paths of the supratrochlear and supraorbital nerves of the ophthalmic branch of the trigeminal nerve. Each electrode pair contacts a self-adhesive conductive gel that at least partially covers one surface of the support for attaching the support to the forehead to be applied to two lateral zones with the exception of an insulating central zone. Each lateral zone has one electrode of the electrode pair, an electric circuit for supplying to the electrode pair electric pulses that have a predefined intensity, and a measurement means for measuring the intensity of the supplied pulses that is connected to the electric circuit.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: July 6, 2021
    Assignee: Cefaly Technology Sprl
    Inventors: Pierre-Yves Muller, Pierre Rigaux
  • Patent number: 11040212
    Abstract: An example of a system for delivering neurostimulation may include a display and an interface control circuit. The interface control circuit may be configured to define a stimulation waveform according to which the neurostimulation is delivered. The stimulation waveform is defined by waveform parameters including one or more user-adjustable parameters. The interface control circuit may include a parameter selector, an effect analyzer, and a parameter generator. The parameter selector may be configured to present values for each user-adjustable parameter on the display and allow the user to select a value for each user-adjustable parameter from the presented values. The effect analyzer may be configured to estimate an interactive effect of different stimuli of the neurostimulation. The parameter generator may be configured to select a rate rule based on the estimated interactive effect and to generate the values for each user-adjustable parameter according to the selected rate rule.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: June 22, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: G. Karl Steinke
  • Patent number: 11039773
    Abstract: An integrated electrode structure can comprise a catheter shaft comprising a proximal end and a distal end, the catheter shaft defining a catheter shaft longitudinal axis. A flexible tip portion can be located adjacent to the distal end of the catheter shaft, the flexible tip portion comprising a flexible framework. A plurality of microelectrodes can be disposed on the flexible framework and can form a flexible array of microelectrodes adapted to conform to tissue. A plurality of conductive traces can be disposed on the flexible framework, each of the plurality of conductive traces can be electrically coupled with a respective one of the plurality of microelectrodes.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: June 22, 2021
    Assignee: St. Jude Medical Cardiology Division, Inc.
    Inventors: Terry L. Sterrett, John J. Crow, Eric Lim, Gregory K. Olson, Jeffrey A. Schweitzer
  • Patent number: 11033731
    Abstract: Methods and apparatuses for transdermal electrical stimulation. Described herein are single-use or limited-use TES apparatuses and methods of using them that include an integrated (e.g., flex-circuit) electrode assembly and controller apparatus including a waveform generator and power supply. Also described herein are TES apparatuses including a cord or wire having current control circuitry and configured to connect a mobile computing device (e.g., smartphone or wearable electronics) to an electrode assembly. Finally, also described herein are intermediate apparatuses including a flex-circuit electrode assembly including a waveform generator but receiving power from a cable connected to a mobile computing device.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: June 15, 2021
    Assignee: Thync Global, Inc.
    Inventors: Douglas Jeffery, Wing Law, Jay Frederick Hamlin, Remi Demers, Rafal Piersiak