Directly Or Indirectly Stimulating Motor Muscles Patents (Class 607/48)
  • Patent number: 11166667
    Abstract: This system for identifying information represented by biological signals is configured so as to detect biological signals (S501), analyze the detected biological signals and then output feature data (S502), determine the respective similarities between the feature data and a plurality of teaching data (S503), store the similarities per time in a time series (S504), and determine information represented by the biological signals on the basis of the plurality of similarities within a prescribed period among the stored similarities in the time series (S505).
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: November 9, 2021
    Assignee: Meltin MMI Co., Ltd.
    Inventors: Masahiro Kasuya, Tatsuya Seki
  • Patent number: 11160980
    Abstract: A stimulation apparatus for a patient is provided, the apparatus comprising an external system configured to transmit transmission signals and an implantable system configured to receive the transmission signals from the external system. The implantable system comprises at least one implantable lead, a first implantable device for connecting to the implantable lead during a first time period and a second implantable device for subsequently connecting to the implantable lead for a second time period.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: November 2, 2021
    Assignee: NALU MEDICAL, INC.
    Inventors: Lakshmi Narayan Mishra, Andre Castillo, Lee Fason Hartley, Christopher Linden, Joseph Christopher Flaherty
  • Patent number: 11160971
    Abstract: A tremor suppression device includes a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region, and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; and apply neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.
    Type: Grant
    Filed: August 25, 2020
    Date of Patent: November 2, 2021
    Inventors: Gaurav Sharma, Patrick Ganzer
  • Patent number: 11141586
    Abstract: A system, method, and apparatus for treating a medical condition by applying transcutaneous electrical stimulation to a target peripheral nerve of a subject. Electrical stimulation is applied to the peripheral nerve via a stimulation electrode pattern under closed-loop control in which EMG responses are monitored and used to adjust stimulation parameters. In response to detecting an unacceptable recording, electrical stimulation is applied to the peripheral nerve under open-loop control.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: October 12, 2021
    Assignee: AVATION MEDICAL, INC.
    Inventors: Alexandru Campean, Jeff A. Weisgarber, Mingming Zhang
  • Patent number: 11144110
    Abstract: A voltage regulator circuit included in a computer system may generate a voltage level on a power supply signal using a source power supply signal and based initial values of one or more operation parameters derived from wafer-level test data. One or more operation characteristics of the voltage regulator circuit may be sampled, by a measurement circuit, at multiple time points to generated measurement data. A control circuit may adapt operation of the voltage regulator circuit based on the measurement data.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: October 12, 2021
    Assignee: Apple Inc.
    Inventors: Jay B. Fletcher, Karthik Manickam, Bo Yang, Vincent R. von Kaenel, Shawn Searles, Hubert Attah, Nir Dahan, Olivier Girard
  • Patent number: 11135438
    Abstract: A system for planning or conducting stimulation includes a display; and a processor that executes instructions configured for: displaying, on the display, a representation of a stimulation effect; obtaining and displaying, on the display, a path for migration of the stimulation effect; receiving a duration or rate for migration of the stimulation effect; and determining a selection of one of more electrodes or optical stimulators for one or more stimulation leads of a stimulation system to produce the stimulation effect and conduct the migration of the stimulation effect along the path according to the duration or rate.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: October 5, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Bradley Lawrence Hershey, Tianhe Zhang, Natalie A. Brill, Rosana Esteller, Jianwen Gu
  • Patent number: 11123312
    Abstract: In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: September 21, 2021
    Assignee: The Regents of the University of California
    Inventors: Daniel C. Lu, V. Reggie Edgerton, Roland R. Roy, Yury P. Gerasimenko
  • Patent number: 11123558
    Abstract: Auricular nerve stimulation techniques for addressing patient disorders, and associated systems and methods. A representative system includes a signal generator having instructions to generate an electrical therapy signal, at least a portion of the electrical therapy signal having a frequency at or above the patient's auditory frequency limit, an amplitude in an amplitude range from about 0.1 mA to about 10 mA, and a pulse width in a pulse width range from 5 microseconds to 30 microseconds. The system further includes at least one earpiece having a contoured outer surface shaped to fit against the skin of the patient's external ear, external ear canal, or both, the at least one earpiece carrying at least two transcutaneous electrodes positioned to be in electrical communication with the auricular innervation of the patient, e.g., the auricular vagal nerve.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: September 21, 2021
    Assignee: Nesos Corp.
    Inventors: Vivek K. Sharma, Konstantinos Alataris, Gary Heit, Jason Sutor, Pankaj Sunkeri
  • Patent number: 11116975
    Abstract: An excitation unit is configured to induce action potentials by applying an excitatory current to a nerve. A blocking unit is configured to block the induced action potentials from propagating along the nerve by applying a blocking current to the nerve. A sensor unit is configured to detect the induced action potentials in the nerve, and to responsively provide a sensor signal that conveys information about the detected induced action potentials. Circuitry is configured (i) to drive the excitation unit to apply the excitatory current, (ii) to drive the blocking unit to apply the blocking current, (iii) while driving the blocking unit to apply the blocking current, to drive the sensor unit to detect the induced action potentials and provide the sensor signal, (iv) to receive the sensor signal, and (v) in response to the sensor signal, to alter a parameter of the blocking current.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: September 14, 2021
    Assignee: BLUEWIND MEDICAL LTD.
    Inventors: Gur Oron, Bar Eytan, Eran Benjamin, Anton Plotkin, Yossi Gross
  • Patent number: 11116933
    Abstract: Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: September 14, 2021
    Assignee: THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michael P. Kilgard, Larry Cauller, Navzer Engineer, Christa McIntyre Rodriguez, Will Rosellini
  • Patent number: 11110287
    Abstract: A system for treating chronic inflammation may include an implantable microstimulator, a wearable charger, and optionally an external controller. The implantable microstimulator may be implemented as a leadless neurostimulator implantable in communication with a cervical region of a vagus nerve. The microstimulator can address several types of stimulation including regular dose delivery. The wearable charger may be worn around the subject's neck to rapidly (<10 minutes per week) charge an implanted microstimulator. The external controller may be configured as a prescription pad that controls the dosing and activity of the microstimulator.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: September 7, 2021
    Assignee: SetPoint Medical Corporation
    Inventors: Michael A. Faltys, Jesse M. Simon, Yiming Liu
  • Patent number: 11096591
    Abstract: A device determines values for one or more metrics that indicate the quality of a patient's sleep based on sensed physiological parameter values. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. The sleep quality metric values may be used, for example, to evaluate the effectiveness of a therapy delivered to the patient by a medical device. In some embodiments, determined sleep quality metric values are automatically associated with the therapy parameter sets according to which the medical device delivered the therapy when the physiological parameter values were sensed, and used to evaluate the effectiveness of the various therapy parameter sets. The medical device may deliver the therapy to treat a non-respiratory neurological disorder, such as epilepsy, a movement disorder, or a psychological disorder. The therapy may be, for example, deep brain stimulation (DBS) therapy.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: August 24, 2021
    Assignee: Medtronic, Inc.
    Inventors: Keith A. Miesel, Kenneth T. Heruth, Jonathan C. Werder, Steve R. LaPorte, Nina M. Graves
  • Patent number: 11090488
    Abstract: The device (1) for the treatment of joint instability and dyskinesia comprises: an inertial sensor (11, 12) for detecting the movements of a limb (2) of a person, adapted to produce movement signals; an electrostimulation element (14) that can be positioned at a predetermined point of the patient's body so as to electrically stimulate muscles involved in the movement of the limb (2); a waveform generator (15) for supplying the electrostimulation element (14); and a processing means (4) connected to the inertial sensor (11, 12) and to the generator (15), comprising: a position module (41) configured to determine positions of the limb (2) on the basis of the movement signals; and a stimulation module (42) configured to produce stimulation signals adapted to control the operation of the generator (15), on the basis of one or more positions of the limb (2) determined by the position module (41).
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: August 17, 2021
    Assignee: NCS LAB S.R.L.
    Inventor: Matteo Mantovani
  • Patent number: 11071494
    Abstract: Multi-modal sensing relating to joint acoustic emission and joint bioimpedance. Custom-design analog electronics and electrodes provide high resolution sensing of bioimpedance, microphones and their front-end electronics for capturing sound signals from the joints, rate sensors for identifying joint motions (linear and rotational), and a processor unit for interpretation of the signals. These components are packed into a wearable form factor, which also encapsulates the hardware required to minimize the negative effects of motion artifacts on the signals.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: July 27, 2021
    Assignee: Georgia Tech Research Corporation
    Inventors: Omer T. Inan, Michael N. Sawka, Jennifer O. Hasler, Hakan Toreyin, Mindy L. Millard-Stafford, Geza Kogler, Sinan Hersek, Caitlin Teague, Hyeon Ki Jeong, Maziyar Baran Pouyan
  • Patent number: 11058541
    Abstract: Provided is a functional, low-profile intercranial device (LID). The LID includes a base portion; at least one cavity associated with the base portion and configured to accept at least one functional component; and at least one conduit having a first end in communication with the at least one cavity. The at least one functional component includes a medicinal, electronic, or optic therapeutic. The at least one conduit is configured to accept the medicinal therapeutic and a second end configured to dispense the therapeutic.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: July 13, 2021
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventor: Chad Gordon
  • Patent number: 11039782
    Abstract: Multi-modal sensing relating to joint acoustic emission and joint bioimpedance. Custom-design analog electronics and electrodes provide high resolution sensing of bioimpedance, microphones and their front-end electronics for capturing sound signals from the joints, rate sensors for identifying joint motions (linear and rotational), and a processor unit for interpretation of the signals. These components are packed into a wearable form factor, which also encapsulates the hardware required to minimize the negative effects of motion artifacts on the signals.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: June 22, 2021
    Assignee: Georgia Tech Research Corporation
    Inventors: Omer T. Inan, Michael N. Sawka, Jennifer O. Hasler, Hakan Toreyin, Mindy L. Millard-Stafford, Geza Kogler, Sinan Hersek, Caitlin Teague
  • Patent number: 11033734
    Abstract: Described herein are systems and methods for the treatment of pain using electrical nerve conduction block (ENCB). Contrary to other methods of pain treatment, the ENCB can establish a direct block of neural activity, thereby eliminating the pain. Additionally, the ENCB can be administered without causing electrochemical damage. An example method can include: placing at least one electrode contact in electrical communication with a region of a subject's spinal cord; applying an electrical nerve conduction block (ENCB) to a nerve in the region through the at least one electrode contact; and blocking neural activity with the ENCB to reduce the pain or other unwanted sensation in the subject.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: June 15, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Niloy Bhadra, Narendra Bhadra, Kevin L. Kilgore, Scott Lempka, Jesse Wainright, Tina Vrabec, Manfred Franke
  • Patent number: 11033739
    Abstract: A training aid stimulator for providing fast perceptive feedback is disclosed. The training aid stimulator includes a first skin electrode and a second skin electrode both for making electrical contact to the body of a user, a charging module, a discharge module connected to one or more of the skin electrodes for a feedback discharging, and a processor for controlling the charging of a capacitor equivalent to a predetermined first voltage level, wherein the processor further being connected to the discharge module for controlling a feedback discharge of the capacitor equivalent. The stimulator comprises a voltage measurement module for measuring the level of charge of the capacitor equivalent, and the processor is configured for keeping the stimulator ready to discharge by repeatedly measuring the level of charge and by providing a maintenance charging when the voltage over said capacitance equivalent is at or below a predetermined second voltage level.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: June 15, 2021
    Inventors: Christian Bergh, Christian Wallenberg, Philip Dahl
  • Patent number: 11013923
    Abstract: A patient-initiated automatic neural tissue control system and methods of providing patient-initiated automatic control of neural tissues are disclosed. The patient-initiated automatic neural tissue control system and methods allow for patient-defined internal initiation of motor control, by initiation of the controlling signals in the contralateral motor area the patient controls (e.g., previously damaged motor areas). The patient-initiated automatic neural tissue control system and methods involve brain signals that initiate from patient-defined motor actions from the contralateral motor area of the patient's brain which stimulates brain areas near the damaged brain areas. The brain areas stimulated near the damaged brain area include brain areas adjacent to the damaged brain area and brain areas below the damaged brain area.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: May 25, 2021
    Inventor: Thomas M. Eubanks
  • Patent number: 11007368
    Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: May 18, 2021
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
  • Patent number: 10980438
    Abstract: An intraoperative neuromonitoring system for evaluating nerve function via a plurality of neural monitoring modalities includes an invasive medical instrument, a plurality of stimulating electrodes, a plurality of peripheral sensors, a patient module, and a control unit in communication with the patient module. The control unit is configured to maintain a range of acceptable values for each of a plurality of different neural monitoring modalities, determine, for each of the plurality of different neural monitoring modalities, whether the respective modality is within the range of acceptable values for that respective modality based on the indication of neuromuscular activity from one or more of the plurality of peripheral sensors, and provide an indication on a common screen displayed via the display, whether each respective neural monitoring modality is inside or outside of the range of acceptable values for that modality.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: April 20, 2021
    Assignee: Depuy Synthes Products, LLC
    Inventors: Corbett Stone, Robin Vaughan, Kabir Gambhir
  • Patent number: 10984675
    Abstract: A training aid stimulator for providing fast perceptive feedback is provided. The training aid stimulator includes a first skin electrode for making electrical contact to the body of a user and a second skin electrode for making electrical contact to the body of a user. A body capacitance charging module is connected to the first skin electrode and a discharge module is connected to the second skin electrode for a feedback discharging of a body capacitance. A processor is connected to the body capacitance charging module for controlling the charging of a body capacitance to a predetermined first voltage level, wherein the processor is connected to the discharge module for controlling a feedback discharge of the body capacitance. The stimulator further comprises a measurement module for measuring the level of charge of the body capacitance.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: April 20, 2021
    Inventors: Christian Bergh, Ulf Bering, Markus Westerberg
  • Patent number: 10973733
    Abstract: A device and method for desynchronizing a patient's neuronal brain activity in which the neuron population is firing in a pathologically synchronized manner. The device includes a stimulation unit that generates an acoustic stimulation signal that includes both a first tone and a second tone. The first tone is provided to shift the phase of the neuronal brain activity of a first subpopulation of the neuron population relative to the phase of the neuronal brain activity of a second subpopulation of the neuron population when the first tone is acoustically received by the patient. Further, the second tone is provided to shift the phase of the neuronal brain activity of the second subpopulation relative to the phase of the neuronal brain activity of the first subpopulation when the second tone is acoustically received by the patient. As a result, the acoustic stimulation signal desynchronizes the stimulated neuron population.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: April 13, 2021
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Peter A. Tass, Hans-Joachim Freund, Oleksandr Popovych, Birgit Utako Barnikol, Joel Niederhauser, Jean-Christophe Roulet, Urban Schnell
  • Patent number: 10940310
    Abstract: Described here are devices, systems, and methods for treating one or more conditions, such as allergic rhinitis, non-allergic rhinitis, nasal congestion, ocular allergy, and/or symptoms associated with these conditions, by providing stimulation to nasal or sinus tissue. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs, and the nasal insertion prongs may be configured to deliver an electrical stimulus to the tissue.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: March 9, 2021
    Assignee: Oculeve, Inc.
    Inventors: James Donald Loudin, Daniel N. Hamilton, Manfred Franke, Douglas Michael Ackermann
  • Patent number: 10940359
    Abstract: An exercise machine inclination device for providing variable exercise intensity on an exercise machine by inclining the exercise machine. The exercise machine inclination device generally includes a base adapted for being positioned upon a floor, a support structure adapted for supporting the exercise machine, a hinge pivotally connecting the base and the support structure and an actuator connected between the base and the support structure, wherein the actuator adjusts an angle of the support structure.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: March 9, 2021
    Assignee: Lagree Technologies, Inc.
    Inventors: Sebastien Anthony Louis Lagree, Samuel D. Cox, Todd G. Remund
  • Patent number: 10926092
    Abstract: Medical device systems and methods for providing spinal cord stimulation (SCS) are disclosed. The SCS systems and methods provide therapy below the perception threshold of the patient. The methods and systems are configured to measure neurological responses to stimulation and use the neurological responses as biomarkers to maintain and adjust therapy. An example of neurological responses includes an evoked compound action potential (ECAP).
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: February 23, 2021
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Rosana Esteller, Rafael Carbunaru
  • Patent number: 10926088
    Abstract: A portable electronic pulse stimulator with integrated Ultrasound and TENS/EMS includes a unit and a electrode pad. The unit includes IC board and housing; the IC board has an Ultrasound output module and a TENS/EMS output module; The electrode pad has Ultrasound therapy head and TENS/EMS electrode. The invention can add the heating function and the heating intensity can be adjusted if needed. At the same time, this invention can add the remote control function, meaning the electronic pulse stimulator can both receive and send data. The unit can work independently and is portable.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 23, 2021
    Assignee: JKH Health Co., Ltd.
    Inventors: Quanqin Dai, Pu Jiang
  • Patent number: 10918332
    Abstract: Systems, devices, and methods for post-surgical joint range of motion measurement, activity monitoring, as well as monitoring compliance with post-operative extremity elevation and cooling recommendations are provided. The system comprises sensor(s) to be attached adjacent a joint of the patient, with limb attachment element(s), applications running on a computing device of the patient and medical practitioner, and a cloud-based backend system.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: February 16, 2021
    Assignee: ZipLine Medical, Inc.
    Inventors: Amir Belson, Keiichiro Ichiryu, Zachary Kimura, Mark Shughart, Harold Sampson, Daren Stewart, Eric Storne, John Tighe
  • Patent number: 10905894
    Abstract: A pain relief device is provided. The pain relief device includes: (i) a body portion including a contact region configured for contacting a subject; and (ii) a monopolar transmitter including a single electrical pole for providing an electrical signal to the body portion for treatment of the subject.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: February 2, 2021
    Assignee: Prezacor, Inc.
    Inventor: Gary Karpf
  • Patent number: 10909884
    Abstract: Disclosed is an electronically adjustable joint, and associated systems and methods. A joint position of a multiple-axis joint, e.g., a 3-axis joint, can be tracked, as the joint moves through two or more dimensions. In an illustrative embodiment, the joint can provide a mechanical equivalent of a physical joint, e.g., a shoulder, elbow, hip, or knee, which can accommodate motion in rotational angle and/or tilt angle. In some embodiments, the joint includes electronically adjustable friction. An illustrative application provide electronically adjustable joints for an aging simulation suit, wherein one or more joints can be controllably stiffened in selective ranges, such that a wearer of the suit can experience the effects of aging, arthritis and/or other ailments. In an illustrative embodiment, a sensor can use four discrete 2-axis magnetometers to calculate the position of the magnet on the arm of the joint, to continuously sense and track the angle of the joint.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: February 2, 2021
    Assignee: Applied Minds, LLC
    Inventors: Donald G. Lariviere, David Foor, Andrew McGraw, Michael Keesling
  • Patent number: 10888698
    Abstract: Apparatus and methodologies for the mitigation and prevention of venous thromboembolism-related disorders resulting from by venous blood stasis. More specifically, repeated cycles of brief bouts of intermittent electrical stimulation are repeated every several minutes to contract at least one target muscle, causing a temporary increase in venous blood flow and blood velocity in the veins in the region of the target muscle(s). The present intermittent electrical stimulation paradigm may be used to mimic physiological responses following voluntary contraction of the target muscle(s), without fatiguing the muscle(s).
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: January 12, 2021
    Assignee: BIOTECHNOLOGY & HEALTH INNOVATIONS INC.
    Inventors: Vivian K. Mushahwar, Einat Ravid, David Shaun Gray
  • Patent number: 10881853
    Abstract: Neuromodulation systems are described comprising a signal generator and at least one electrode. The at least one electrode can be configured to deliver a stimulation to a mammal, wherein the stimulation includes a biphasic signal and an overlapping high frequency pulse thereby inducing voluntary movement in the individual. Methods of administering the stimulation are also described.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: January 5, 2021
    Assignee: The Regents of the University of California, A California Corporation
    Inventors: Victor Reggie Edgerton, Yury P. Gerasimenko, Nicholas A. Terrafranca, Parag Gad
  • Patent number: 10881849
    Abstract: Systems, methods, and devices are provided herein providing electrical muscle stimulation (EMS). In some instances, an EMS device may be provided. The EMS device may be compact, light, and unobtrusive such that it can be used by a person going about his or her daily activities. In some instances, the EMS device may comprise additional sensors for increased functionality and may be capable of interacting with additional devices or platforms to provide a full-fledged EMS device capability.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: January 5, 2021
    Assignee: POWERDOT, INC.
    Inventors: Alexey Pisarev, Vladimir Pisarev
  • Patent number: 10874859
    Abstract: An example of a system to program a neuromodulator to deliver neuromodulation to a neural target using a plurality of electrodes may comprise a programming control circuit configured to determine target energy allocations for the plurality of electrodes based on at least one target pole to provide a target sub-perception modulation field, and normalize the target sub-perception modulation field, including determine a time domain scaling factor to account for at least one property of a neural target or of a neuromodulation waveform, and apply the time domain scaling factor to the target energy allocations.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: December 29, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Tianhe Zhang, Changfang Zhu, Que T. Doan
  • Patent number: 10864373
    Abstract: One aspect of the present disclosure is a system including a waveform generator, a controller, and an electrical contact. The waveform generator is for generating an electrical nerve conduction block (ENCB). The controller is coupled with the waveform generator. The controller is configured to receive an input comprising at least one parameter to adjust the ENCB. The electrical contact is coupled with the wave-form generator. The electrical contact is configured to be placed into contact with a nerve. The electrical contact comprises a high charge capacity material that prevents formation of damaging electro-chemical products at a charge delivered by the ENCB. The electrical contact is configured to deliver the ENCB to the nerve to block transmission of a signal related to a pain through the nerve.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: December 15, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Niloy Bhadra, Narendra Bhadra, Kevin L. Kilgore, Scott Lempka, Jesse Wainright, Tina Vrabec, Manfred Franke
  • Patent number: 10857363
    Abstract: Devices and methods are provided to treat acute and chronic heart failure by using one or more implantable or non-implantable sensors along with phrenic nerve stimulation to reduce intrathoracic pressure and thereby reduce pulmonary artery, atrial, and ventricular pressures leading to reduced complications and hospitalization.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: December 8, 2020
    Assignee: RMX, LLC
    Inventor: Amir J. Tehrani
  • Patent number: 10857354
    Abstract: An example of a system to program a neuromodulator to deliver neuromodulation to a neural target using a plurality of electrodes may comprise a programming control circuit configured to determine target energy allocations for the plurality of electrodes based on at least one target pole to provide a target sub-perception modulation field, calibrate a plurality of electrode groups in the plurality of electrodes where each of the plurality of electrode groups is in an electrode configuration and includes an electrode set of at least one electrode from the plurality of electrodes, including for each of the plurality of electrode groups receive a feedback metric to delivery of modulation energy to the neural target, and normalize the target sub-perception modulation field, including determine a space domain scaling factor using the feedback metric to account for actual electrode-tissue coupling, and apply the space domain scaling factor to the target energy allocations.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: December 8, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Tianhe Zhang, Changfang Zhu, Que T. Doan
  • Patent number: 10843001
    Abstract: Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for modulation program recommendation are disclosed. A particular embodiment includes receiving, from multiple computing devices, ratings for modulation programs executed by implantable medical devices for a plurality of patients, ranking the modulation programs based on the received ratings and based on at least one characteristic of the patients and the symptoms described by the patients, receiving a recommendation request for a modulation program for a particular patient; and transmitting one or more of the highest ranking modulation programs in response to the request for a modulation program for the particular patient.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: November 24, 2020
    Assignee: Nevro Corp.
    Inventor: Jon Parker
  • Patent number: 10814137
    Abstract: Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: October 27, 2020
    Assignee: Nyxoah SA
    Inventors: Adi Mashiach, Tim Ruytjens, Itzik Mashiach
  • Patent number: 10796596
    Abstract: Described is a closed-loop intervention control system for memory consolidation in a subject. During operation, the system simulates memory changes of a first memory in a subject during waking encoding of the memory, and then while the subject is sleeping and coupled to an intervention system. Based on the simulated memory changes, the system predicts behavioral performance for the first memory, the behavioral performance being a probability that the first memory can be recalled on cue. The system can be used to control operation (e.g., turn on or off) of the intervention system with respect to the first memory based on the behavioral performance of the first memory determined by the simulation.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: October 6, 2020
    Assignee: HRL Laboratories, LLC
    Inventors: Steven W. Skorheim, Michael D. Howard, Praveen K. Pilly
  • Patent number: 10786674
    Abstract: In some examples, a system may include a plurality of electrodes, electrical stimulation circuitry, and a controller. The controller may be configured to select one or more parameters of therapy to be delivered to a brain of a patient and to control the electrical stimulation circuitry to deliver the therapy to the brain of the patient based on the selected parameters and via a first one or more electrodes of the plurality of electrodes. The parameters may be defined based on a first plurality of electrical signals sensed at a plurality of different positions within the brain of the patient when electrical stimulation is not delivered at each of the positions and a second plurality of electrical signals sensed at each of the plurality of different positions within the brain of the patient in response to electrical stimulation delivered at each of the positions at a plurality of different intensities.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: September 29, 2020
    Assignee: Medtronic, Inc.
    Inventors: Jianping Wu, Dwight E. Nelson, Gabriela C. Molnar
  • Patent number: 10779730
    Abstract: A method and an electrode for monitoring electrical activity in a nerve are provided along with a method of fabricating such an electrode. The electrode includes a cuff formed from a chronically-implantable material that, when implanted, extends at least partially around an external periphery of the nerve. A plurality of contacts are supported by the cuff to be arranged adjacent to different regions of the nerve distributed along a transverse direction of the nerve when the cuff is implanted. A multiplexer is coupled to the cuff to be implanted for receiving electrical signals introduced to the contacts by the nerve and multiplexing, in vivo, the electrical signals to be transmitted to an external receiver over a shared communication channel.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: September 22, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Dominique M. Durand, Brian Wodlinger
  • Patent number: 10782790
    Abstract: A system and method to collect gesture input through wrist tendon and muscle sensing are disclosed. A particular embodiment includes: a sensor array integrated into a wristband, the sensor array including a plurality of pressure sensors positioned for contact with particular locations on a wrist of a user wearing the wristband; and a controller unit, the controller unit including a communication interface, the controller unit being configured to: receive a plurality of sensor signals generated by the sensor array, the plurality of sensor signals corresponding to movement detected at particular locations on the wrist of the user; convert the plurality of sensor signals to a digital representation; generate a composite data packet by combining the plurality of converted sensor signals into a composite digital value; and provide the composite digital value to a processing unit of a wearable device for use in control of a user interface in the wearable device.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: September 22, 2020
    Assignee: Intel Corporation
    Inventor: Marcio Juliato
  • Patent number: 10772523
    Abstract: A patch including a fiducial layer, an adhesive, and a sensor layer. The fiducial layer having a surface adapted to secure to a portion of skin on a patient, wherein the fiducial layer further includes a plurality of fiducial markers having at least one of acoustic properties, material density, and proton content different from those of human tissue. The adhesive being disposed along the surface of the fiducial layer. The sensor layer removably secured to a side of the fiducial layer and positionable distal the skin of the patient. The sensor layer including a plurality of sensors evenly spaced from one another, adapted to be in electrical communication with the skin of the patient, and each adapted to measure at least electric field or impedance.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: September 15, 2020
    Assignee: Medicomp, Inc.
    Inventors: Sean Marcus, Anthony Balda, Scott Baskerville, George Koos
  • Patent number: 10765368
    Abstract: Exemplary implementations may provide objective, continuous, and clinically useful assessment of asthma control in subjects including young children using a device that is compact, non-intrusive, and simple. The device may include a water-resistant, flexible patch that can be comfortably worn for two weeks or more. In some implementations, the patch may resemble a Band-Aid® that is placed on the supra-sternal notch. The device may record respiratory sounds that can be analyzed to identify coughing and wheezing episodes. The device may operate in different modes including ones for assessment of nocturnal symptoms, exercise-induced asthma, and overall asthma control. The device may be useful for objectively assessing asthma control to aid clinical therapy, and for an improved way to diagnose exercise-induced asthma.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: September 8, 2020
    Assignee: LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER
    Inventor: Ruey-Kang Chang
  • Patent number: 10765856
    Abstract: A system and method for providing therapy to a patient can include a monitoring unit and a therapy unit. The monitoring unit can have a user interface and one or more sensors to measure patient data. The therapy unit can have a stimulator for generating electrical stimulation and a microcontroller for controlling the generation of the electrical stimulation based on the measured patient data.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: September 8, 2020
    Assignee: Cala Health, Inc.
    Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Richard Hamner, Paula Jean Chidester, Scott Lee Delp, Terence D. Sanger
  • Patent number: 10765862
    Abstract: Methods and systems for treating sleep disordered breathing by stimulating nerves that innervate the palatoglossus and/or the palatopharyngeus muscle are provided. Such therapy can be used in conjunction with hypoglossal nerve stimulation.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: September 8, 2020
    Assignee: VANDERBILT UNIVERSITY
    Inventor: David T. Kent
  • Patent number: 10758724
    Abstract: A delivery and deployment device may include a handle assembly and a shaft extending distally from the handle assembly. A device containment housing may be coupled to a distal region of the shaft and may extend distally therefrom. The distal containment housing may be configured to accommodate at least a portion of the IMD therein. The IMD may, for example, be a leadless pacemaker, a lead, a neurostimulation device, a sensor or any other suitable IMD. A plurality of electrodes may be distributed about an exterior surface of the device containment housing such that at least some of the plurality of electrodes may be positioned to test a potential IMD deployment location before deploying the IMD.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: September 1, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Brendan Early Koop, Yinghong Yu, Qi An, Keith R. Maile, Pramodsingh Hirasingh Thakur, Bin Mi, Jeffrey E. Stahmann, Viktoria A. Averina, Krzysztof Z. Siejko, Michael J. Kane, Allan Charles Shuros, Arjun D. Sharma, Brian Soltis
  • Patent number: 10751532
    Abstract: Disclosed herein is a method of treating a disease, comprising: (a) implanting an array of electrodes on one or more targeted nerves and/or targeted muscles; and (b) treating the disease by selectively stimulating the one or more targeted nerves and/or targeted muscles through electrical pulses delivered from the array. Also disclosed herein is a device, comprising a plurality of electrodes that have the capacity to be inserted in or around a facial nerve. Further disclosed herein is a method of treating facial paralysis and/or damage in a subject, comprising: (a) detecting the level of contraction of individual muscles on a healthy, non-paralyzed side of the face of the subject; and (b) treating facial paralysis by a direct targeted stimulation of the corresponding muscles or nerve fibers on a paralyzed side of the face of the subject.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: August 25, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Harrison W. Lin, Hamid Djalilian, Ronald Sahyouni
  • Patent number: 10737124
    Abstract: Methods, systems, and devices are disclosed for acoustic nerve stimulation. In one aspect, a system for acoustic nerve stimulation is disclosed. The system comprises an ultrasonic phased array chip device deployable into a living organism, the ultrasonic phased array chip device including a substrate and an acoustic signaling module on the substrate that includes an array of acoustic transducer elements operable to generate ultrasonic beams based on electronic control signals, capable to propagate the ultrasonic beams through biological nervous tissue to affect nervous signal firing; and a transmitter device wearable on an exterior of the living organism, wirelessly couplable with the ultrasonic phased array chip device to transmit the electronic control signals.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: August 11, 2020
    Assignee: Cornell University
    Inventor: Amit Lal