Directly Or Indirectly Stimulating Motor Muscles Patents (Class 607/48)
  • Patent number: 12004861
    Abstract: A device includes an EMG processing application operable with a processing module to receive an output signal from EMG testing, wherein the output signal represents electrical activity of at least one muscle. The EMG processing application is operable to process the output signal to detect at least one type of waveform of a plurality of types of waveforms from the output signal and display the detected at least one type of waveform.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: June 11, 2024
    Inventor: Tomasz Andrzej Kosierkiewicz
  • Patent number: 11980765
    Abstract: A neurostimulation system configured for providing neurostimulation therapy to a patient. A user customizes a pulse pattern on a pulse-by-pulse basis. Electrical stimulation energy is delivered to at least one electrode in accordance with the customized pulse pattern.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: May 14, 2024
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Michael A. Moffitt
  • Patent number: 11964189
    Abstract: A training device includes a force receiving component, a location detector, a resistance generator, and a controller. The force receiving component moves along a closed trajectory. The location detector is configured to detect a location of the force receiving component in the closed trajectory and to output a location signal. The resistance generator is configured to exert a resistance on the force receiving component. The controller controls the resistance generator to adjust the resistance based on the location signal.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: April 23, 2024
    Assignee: WISTRON CORPORATION
    Inventors: Chuan-Yen Kao, Yao-Tsung Chang, Chih-Yang Hung
  • Patent number: 11957902
    Abstract: A living body stimulator includes a low-frequency pulse generator, a high-frequency signal generator, a synthesizer for forming a synthesized waveform where a high-frequency signal of the high-frequency signal generator is superimposed on a low-frequency pulse signal of the low-frequency pulse generator, a waveform control signal circuit for controlling the synthesizer so that one cycle includes an ON period of the synthesized waveform where the high-frequency signal is superimposed on the low-frequency pulse signal and an OFF period where the high-frequency signal is not superimposed on the low-frequency pulse signal, and an output transformer for receiving the synthesized waveform. An impedance on an output side of the output transformer is set such that a voltage of the synthesized waveform gradually increases and decreases during the ON period on the output of the output transformer when pads connected to the output of the output transformer are attached to the living body.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: April 16, 2024
    Inventor: Ryoji Kuwahata
  • Patent number: 11957905
    Abstract: An electric current stimulation device includes a first electrode and a second electrode that are arranged in a body, and an output circuit that outputs an electric signal; wherein the electric signal by which the user feels no pain is output from the output circuit, and the electric signal is applied to a distal portion of extremities or near the same by the first electrode and the second electrode when arranging the body at the distal portion of the extremities of the user or near the same.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: April 16, 2024
    Assignee: ITO CO., LTD.
    Inventors: Tsukasa Kurahashi, Mayuko Kurahashi, Daigo Yoshida
  • Patent number: 11957906
    Abstract: This external stimulus application system is structured so as to comprise: an external stimulus unit that applies an external stimulus to a target area of a user's body; a detection unit that detects changes in a detected area of the user's body during an action of the user; a control unit that causes the external stimulus unit to produce a stimulus if a detected value detected by the detection unit satisfies a prescribed condition; and a storage unit that stores the detected value.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: April 16, 2024
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hidetoshi Tomita, Yuki Kondo, Motoyasu Yasui, Kenji Iida
  • Patent number: 11944821
    Abstract: A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: April 2, 2024
    Assignee: The Cleveland Clinic Foundation
    Inventors: J. Luis Lujan, Ashutosh Chaturvedi, Cameron McIntyre
  • Patent number: 11931571
    Abstract: A mobility augmentation system assists a user's movement by determining a corresponding electrical stimulation for the movement. A wearable stimulation array includes sensors, electrodes, an electrode multiplexer, and a controller that executes the mobility augmentation system. The sensors measure movement data, and the mobility augmentation system applies a movement model to the measured movement data. The model can determine different electrical actuation instructions depending on the movement stimulated. For example, to stimulate a knee flexion, the movement model output enables a first set of the electrodes to operate as cathodes and a second set of electrodes to operate as anodes. To stimulate a knee extension, the first set of electrodes can be enabled to operate as anodes and a third set of electrodes as cathodes. The user can provide feedback of the applied stimulation, which the system can use to retrain the model and optimize the stimulation to the user.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: March 19, 2024
    Assignee: Cionic, Inc.
    Inventors: Jeremiah Robison, Lina Avancini Colucci, Ren Gibbons
  • Patent number: 11931579
    Abstract: Passive tissue biasing circuitry in an Implantable Pulse Generator (IPG) is disclosed to facilitate the sensing of neural responses by holding the voltage of the tissue to a common mode voltage (Vcm). The IPG's conductive case electrode, or any other electrode, is passively biased to Vcm using a capacitor, as opposed to actively driving the (case) electrode to a prescribed voltage using a voltage source. Once Vcm is established, voltages accompanying the production of stimulation pulses will be referenced to Vcm, which eases neural response sensing. An amplifier can be used to set a virtual reference voltage and to limit the amount of current that flows to the case during the production of Vcm. In other examples, circuitry can be used to monitor the virtual reference voltage as useful to enabling the sensing the neural responses, and as useful to setting a compliance voltage for the current generation circuitry.
    Type: Grant
    Filed: February 20, 2023
    Date of Patent: March 19, 2024
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Goran N. Marnfeldt
  • Patent number: 11931583
    Abstract: A neurostimulation system comprises a control system configured to monitor a patient receiving neurostimulation therapy. The neurostimulation therapy has a stimulation cycle comprising a stimulation ON period, in which the patient is receiving neurostimulation, and a stimulation OFF period, in which the patient is not receiving neurostimulation. The control system is programmed to receive electrocardiogram (ECG) data from the patient receiving the neurostimulation therapy. The control system is further programmed to monitor a heart rate of the patient based on the ECG data over at least one stimulation cycle of the neurostimulation therapy. The control system is further programmed to generate an indication of signal stability to be displayed to a user based on the received ECG data.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: March 19, 2024
    Assignee: LivaNova USA, Inc.
    Inventors: Imad Libbus, Scott R. Stubbs, Bruce H. KenKnight, Scott Mazar, Badri Amurthur
  • Patent number: 11911604
    Abstract: A garment is wearable on an anatomical region and includes electrodes contacting the anatomical region when the garment is worn on the anatomical region. An electronic controller is configured to detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes, and identify tremors as a function of anatomical location and time based on the EMG signals.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: February 27, 2024
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Gaurav Sharma, Patrick Ganzer
  • Patent number: 11883656
    Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.
    Type: Grant
    Filed: October 20, 2022
    Date of Patent: January 30, 2024
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: David A. Friedenberg, Po-Hsu Chen, Samuel Colachis, Nicholas Annetta, Douglas E. Boyd, Collin Dunlap, Ian W. Baumgart, Herbert S. Bresler
  • Patent number: 11872388
    Abstract: An electrostimulation method of at least one muscle group responsible for performing a complex movement includes associating to each of the muscles of the at least one muscle group an electrostimulation channel provided with at least one respective electrode. Each electrostimulation channel is suitable to transmit to the respective muscle bipolar electrical pulses in sequence. For all the electrostimulation channels, a same cycle time defining a repeatable period of stimulation is determined, in which, within the stimulation period, each channel performs its own stimulation sequence. Each stimulation period is sub-divided into two half-periods of equal duration. Each half-period is sub-divided into sub-intervals of the same duration. At least one of the sub-intervals is a stimulation sub-interval wherein a basic sequence of pulses including one or more pulse packets is performed, each pulse packet being given by a predetermined sequence of individual bipolar electric pulses.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: January 16, 2024
    Assignee: VIKTOR S.R.L.
    Inventor: Viktor Terekhov
  • Patent number: 11839759
    Abstract: An electrical stimulation training and neuromuscular rehabilitation system including a machine-washable stimulation suit with multiple electrodes to provide controlled stimulation of various muscle groups is provided. The stimulation suit may also include one or more integrated biosensors to provide diagnostic capability in addition to stimulation. The system may also include a software platform executable on a user computing device (such as a tablet) that may facilitate control of the stimulation programs (e.g., intensity level, duration, isolation of individual muscle groups vs. full body stimulation) of one or more stimulation suits by the wearer or a fitness practitioner or trainer and/or that may facilitate intervention by a medical provider through a remote telemedicine platform.
    Type: Grant
    Filed: March 21, 2023
    Date of Patent: December 12, 2023
    Assignee: NEURO20 TECHNOLOGIES CORP.
    Inventors: Michael Howard Finkelstein, Dennis Michael Schmitt, Jana Schmitt
  • Patent number: 11839762
    Abstract: The present disclosure provides a neuromodulation medical treatment device and a medical treatment neuromodulation method for stimulating peripheral nerves. The device comprises a pulse generator and at least one active electrode connected to the pulse generator. The at least one active electrode has an electrically conductive surface of less than or equal to 0.3100 square inch and the electrically conductive surface is attachable to a patient's skin in a proximity of branches of peripheral nerves. The at least one active electrode is adapted to stimulate via the electrically conductive surface the peripheral nerves by electrical pulses generated by the pulse generator. The control unit controls the pulse generator and sets at least one parameter of generated electrical pulses.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: December 12, 2023
    Assignee: STIMVIA s.r.o.
    Inventors: Lukas Doskocil, Zdenek Krcil, Michal Drahos
  • Patent number: 11819332
    Abstract: A method for determining a desired location at which to apply a neural therapy. An array of electrodes is positioned proximal to neural tissue. A stimulus is applied from the array which evokes a neural compound action potential response in the neural tissue proximal to the array. A plurality of electrodes of the array simultaneously obtain respective measurements of the neural compound action potential response. From the measurements of the neural compound action potential response a desired location for a neural therapy is determined.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: November 21, 2023
    Assignee: Saluda Medical Pty Ltd
    Inventors: John Louis Parker, Dean Michael Karantonis
  • Patent number: 11813454
    Abstract: A method of stimulating muscle in a person having neurological damage, by applying electric current to nerves at an area above an area of neurological damage, bypassing or bridging an area of neurological damage, and moving the muscle in a natural manner. A method of moving muscles of a paraplegic or a person who suffers from other movement-related disorders of the body by applying electric current to nerves at an area above an area of neurological damage, bypassing or bridging an area of neurological damage, and moving normally non-functioning muscles and moving normally non-functioning limbs.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: November 14, 2023
    Assignee: IINN, Inc.
    Inventor: Jawad A. Shah
  • Patent number: 11786743
    Abstract: A medical device stores a set of stimulation profiles, wherein each stimulation profile of the set of stimulation profiles is associated with a set of values for stimulation parameters; selects from the set of stimulation profiles, one or more active stimulation profiles; produces, by a stimulation generator, multiple electrical pulses based on the one or more active stimulation profiles; and separately controls parameter values of respective individual pulses of the multiple pulses.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: October 17, 2023
    Assignee: Medtronic, Inc.
    Inventors: Erik J. Peterson, Mandla Shongwe
  • Patent number: 11786737
    Abstract: Medical device systems and methods for providing spinal cord stimulation (SCS) are disclosed. The SCS systems and methods provide therapy below the perception threshold of the patient. The methods and systems are configured to measure neurological responses to stimulation and use the neurological responses as biomarkers to maintain and adjust therapy. An example of neurological responses includes an evoked compound action potential (ECAP).
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: October 17, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Rosana Esteller, Rafael Carbunaru
  • Patent number: 11779762
    Abstract: One aspect of the present disclosure is a system including a waveform generator, a controller, and an electrical contact. The waveform generator is for generating an electrical nerve conduction block (ENCB). The controller is coupled with the waveform generator. The controller is configured to receive an input comprising at least one parameter to adjust the ENCB. The electrical contact is coupled with the waveform generator. The electrical contact is configured to be placed into contact with a nerve. The electrical contact comprises a high charge capacity material that prevents formation of damaging electro-chemical products at a charge delivered by the ENCB. The electrical contact is configured to deliver the ENCB to the nerve to block transmission of a signal related to a pain through the nerve.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: October 10, 2023
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Niloy Bhadra, Narendra Bhadra, Kevin L. Kilgore, Scott Lempka, Jesse Wainright, Tina Vrabec, Manfred Franke
  • Patent number: 11771888
    Abstract: A first electrode, a second electrode, a third electrode and a fourth electrode are placed on a head of the patient. The electrodes are electrically connected to a master unit or sub-control unit that generates a first stimulation signal, during a first time period, to the first and second electrodes to stimulate the brain inside the head. The third and fourth electrodes receive a first brain signal, during a second time period, and forwards the first brain signal to the master unit or sub-control unit which analyzes the first brain signal and adapting a second stimulation signal based on information in the first brain signal.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: October 3, 2023
    Assignee: EXONEURAL NETWORK AB
    Inventors: Lars Dernebo, Fredrik Lundqvist
  • Patent number: 11759625
    Abstract: A electrical treatment device (100) includes a band-like member (20), a first electrode portion (41), a second electrode portion (42), a first mark portion (31) configured to be aligned with a specific position of a right lower limb when the band-like member (20) is wrapped around the right lower limb such that the first electrode portion (41) is guided to a first target position and the second electrode portion (42) is guided to a second target position, and a second mark portion (32) configured to be aligned with a specific position of a left lower limb when the band-like member (20) is wrapped around the left lower limb such that the first electrode portion (41) is guided to a third target position and the second electrode portion (42) is guided to a fourth target position.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: September 19, 2023
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventors: Tamaki Ito, Tsuyoshi Ogihara, Taiki Yukutake
  • Patent number: 11759674
    Abstract: A ground-effect footplate against which a user applies plantar force and moves their foot in 3D across all seven lower-extremity biomechanical axes to accomplish specific as well as global ambulatory objectives related to lower extremity performance improvement, injury prevention and rehabilitation. A device comprising at least one articulating leg connected to a ground-effect footplate and a surface for a user to position against. The device can be used in conjunction with software to create virtual ambulatory environments that mimic GRFVs and cause moments of force that initiate muscular activations that substantially mimic human ambulation, and can couple those movements with non-functional movements in order to improve ROM, speed, strength, and proprioception.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: September 19, 2023
    Inventor: Andre Foucault
  • Patent number: 11752339
    Abstract: Systems and methods of generating and applying a synthetic neuromodulatory signal are described. A subject may be put under a particular condition that causes an effect in the subject. While the subject is under the condition, a recording of neurogram signals derived from the condition can be made from the subject. For example, neuronal signals traveling on the vagus nerve of the subject may be monitored and recorded. The neurogram may then be used to create a synthetic neuromodulatory signal that can be administered to a user. When the synthetic neuromodulatory signal is administered to the user, the user may experience the same effect as the subject that had been placed in the condition, even though the user was never put under the same condition.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: September 12, 2023
    Assignee: SRI International
    Inventors: Christopher Connolly, Patrick Lincoln, Maneesh Yadav, John Cornwell, Bhaskar Ramamurthy
  • Patent number: 11738195
    Abstract: A portable electrical stimulation device is disclosed. In one aspect, the device includes a pair of electrodes configured to be electrically coupled to a user and a wave generator configured to provide an electrical signal to the user via the pair of electrodes. The wave generator is further configured to generate the electrical signal at one of a plurality of levels. Each of the plurality of levels is defined by at least a frequency, a peak voltage, and a peak current. For each of the levels the frequency is in a range of about 50 Hz-about 500 Hz, the peak voltage is in a range of about 40 V-about 250 V, the peak current is in a range of about 25 mA-about 150 mA, and the frequency and the peak voltage have a generally inverse relationship.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: August 29, 2023
    Assignee: NuEnerchi, Inc.
    Inventors: Sam Ira Young, Jeffrey Karl Lucas, Bruce Wayne Nash, John R Haggis, Robert M Salter, III
  • Patent number: 11724110
    Abstract: A stimulation therapy system dynamically modifies therapy intensity based on measured neurotransmitter levels. In some examples, the system delivers, via an electrode implanted in a brain of a patient and stimulation circuitry, an electrical stimulus; monitors an electrical current generated by the stimulation circuitry to deliver the electrical stimulus; determines, based on the electrical current, a value representative of a concentration of dopamine in the brain of the patient; determines, based on the value representative of the concentration of dopamine, a value for one or more stimulation parameters that at least partially define electrical stimulation therapy; and delivers, via the electrode, the electrical stimulation therapy.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: August 15, 2023
    Assignee: Medtronic, Inc.
    Inventors: Jadin C. Jackson, Alan Shi
  • Patent number: 11717682
    Abstract: Apparatus for transcutaneous electrical nerve stimulation in humans, the apparatus comprising: a housing; a stimulation unit mounted within the housing for electrically stimulating nerves; an electrode array releasably mounted to the housing and connectable to the stimulation means, the electrode array comprising a plurality of electrodes for electrical stimulation of nerves; a control unit mounted to the housing and electrically connected to the stimulation unit for controlling at least one characteristic of the stimulation unit; a monitoring unit mounted to the housing and electrically connected to the stimulation unit for monitoring at least one characteristic of the stimulation unit; a user interface unit mounted to the housing and electrically connected to the control unit for controlling the stimulation unit; a display unit mounted to the housing and electrically connected to the control unit and the monitoring unit for displaying the status of the stimulations unit; and a strap attached to the housing;
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: August 8, 2023
    Assignee: NeuroMetrix, Inc
    Inventors: Shai N. Gozani, Xuan Kong, Andres Aguirre, Glenn Herb, Marc Cryan, Michael Williams
  • Patent number: 11684540
    Abstract: A device, system and method for increasing air intake by a subject is described. The device includes a vibration motor and a control unit for controlling vibrational motion output by the vibration motor. The methods include positioning the vibration motor on one or more limbs of a subject, and stimulating nerves in the limbs via the generated vibrational motion, whereby the stimulated nerve signals the brain to increase breathing rate or air intake by the subject. Accordingly, embodiments of the device activate nerve fibers that carry kinesthetic cues from the limbs in a pattern that simulates normal limb motion, and thus triggers inherent reflexes that increase ventilation in response to such motion.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: June 27, 2023
    Assignee: The Regents of the University of California
    Inventors: Ronald M. Harper, Mary Ann Woo, Sergey Shaboyan, Paul Macey
  • Patent number: 11679492
    Abstract: A locking device including a first frame including an insert hole and a first magnetic body, a second frame including an insert recess communicating with the insert hole, and a second magnetic body disposed to face the first magnetic body with a polarity opposite to a polarity of the first magnetic body, and an insert member including a slider inserted into the insert hole and configured to slide relative to the first frame, and a third magnetic body disposed on one side of the slider is provided.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: June 20, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Se-Gon Roh, Jeonghun Kim, Minhyung Lee, Youn Baek Lee, Jongwon Lee, Byungjune Choi, Hyun Do Choi
  • Patent number: 11672984
    Abstract: A gait management apparatus applies stimulation to a user suffering from a neurological disease (such as Parkinson's Disease) gait dysfunction. Motion sensors are arranged to be worn by a patient, and electrical stimulation electrodes are on the legs for stimulation. A controller receives motion sensing signals, and processes these signals to generate stimulation signals for operation of the electrodes to stimulate limb movement upon detection of a gait abnormality. There may be a user actuator for user actuation of electrical stimulation, and the inputs may be a series of taps. The controller may provide signals to prevent occurrence of freezing of gait when it senses that a patient is walking or has an intention to walk. Also, it may apply stimulation at an intensity level which is insufficient for functional muscle stimulation but sufficiently high to trigger activation of efferent nerves.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: June 13, 2023
    Assignee: National University of Ireland, Galway
    Inventors: Gearóid Ó Laighin, Leo Quinlan, Dean Sweeney, Gavin Corley, James Feehilly, Patrick Browne
  • Patent number: 11660444
    Abstract: A subcutaneously implantable device is implantable into a body of a patient, and includes a prong and an electrode. The prong has a contact portion at or adjacent to a distal end thereof that is configured to contact an organ, a nerve, and/or a tissue of the patient. The prong is constructed to apply pressure to the organ, the nerve, and/or the tissue so as to maintain contact between the contact portion and the organ, the nerve, and/or the tissue without fixing the contact portion to the organ, the nerve, and/or the tissue. The electrode is provided at the contact portion of the prong, is configured to contact the organ, the nerve, and/or the tissue, and is electrically coupled or couplable with circuitry that is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to the organ, the nerve, and/or the tissue.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: May 30, 2023
    Assignee: Manicka Institute LLC
    Inventor: Yatheendhar D. Manicka
  • Patent number: 11660461
    Abstract: A tissue stimulation device comprising: a source; a control unit; a decoupled output stage circuit connected to the source and the control unit; a signal generator connected to the input of the decoupled output stage circuit and the control unit; an analog demultiplexer connected to the output stage circuit decoupled by a PE signal and an out signal, the analog demultiplexer is connected to the control unit, and a transducer array is connected to the output of the analog demultiplexer; wherein the control unit selects the output of the analog demultiplexer that allows switching of the PE and out signals to activate the transducers in the transducer array to stimulate tissue.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: May 30, 2023
    Assignee: PANACEA QUANTUM LEAP TECHNOLOGY LLC
    Inventor: Francisco Javier Velasco Valcke
  • Patent number: 11662395
    Abstract: The disclosure provides a soak tester apparatus for testing an implantable enclosure having an impedance engine, a multiplexer and a removably attached cartridge, which cartridge has a plurality of threads, comprising a Faraday cage housing; a receptacle disposed within the Faraday cage housing, wherein the receptacle is configured to host an implantable enclosure having an impedance engine, a multiplexer and a removably attached cartridge, which cartridge has a plurality of threads; and a pigtail disposed within the Faraday cage housing having a charging coil configured to power the implantable enclosure.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: May 30, 2023
    Assignee: NEURALINK CORP.
    Inventors: John W. F. To, Srinivasan Ramakrishnan, Julian Borrey, Russell Ohnemus, Joshua S. Hess, Robin E. Young, Sonal Pinto
  • Patent number: 11654285
    Abstract: An example of a neurostimulation system may include a programming control circuit and a stimulation control circuit. The programming control circuit may be configured to program a stimulation device for delivering the neurostimulation according to a stimulation program specifying a present stimulation field set including stimulation field(s) each defined by a set of active electrodes selected from a plurality of electrodes. The stimulation control circuit may be configured to determine the stimulation program and may include field programming circuitry that may be configured to set the present stimulation field set to an initial stimulation field set specifying stimulation fields allowing for the delivery of the neurostimulation to produce an intended effect and to identify an optimal stimulation field set that satisfies one or more optimization criteria by removing stimulation field(s) from the initial stimulation field set.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: May 23, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Michael A. Moffitt, Rafael Carbunaru
  • Patent number: 11656693
    Abstract: An electronic device tracks, for a user performing a target acquisition movement within a 3D space, movement parameters of a plurality of input devices of the user. The electronic device predicts, for the user, a region of interest within the 3D space, based on the movement parameters. The region of interest includes a plurality of targets in close proximity. The electronic device predicts an endpoint of the target acquisition movement, within the region of interest. In some embodiments, the plurality of input devices includes an eye tracking input device, each input device corresponds to a predefined input device type, and the movement parameters include gaze data from the eye tracking input device. In some embodiments, input devices includes an eye tracking input device, a head-mounted display, and a hand-held controller, and the user's eye, hand, and head movements are coordinated.
    Type: Grant
    Filed: January 5, 2022
    Date of Patent: May 23, 2023
    Assignee: META PLATFORMS TECHNOLOGIES, LLC
    Inventors: Rorik Henrikson, Tovi Samuel Grossman, Sean Edwin Trowbridge, Hrvoje Benko, Daniel John Wigdor, Marcello Giordano, Michael Glueck, Tanya Renee Jonker, Aakar Gupta, Stephanie Santosa, Carolina Brum Medeiros, Daniel Clarke
  • Patent number: 11647962
    Abstract: A behavioral state of a brain is classified by automatically selecting one or more sensors based on the signals received from each sensor and one or more selection criteria using one or more processors, calculating at least one measured value from the signal(s) of the selected sensor(s), classifying the behavioral state as: (a) an awake state whenever the measured value(s) for the selected sensor(s) is lower than a first threshold value, (b) a sleep state (N2) whenever the measured value(s) for the selected sensor(s) is equal to or greater than the first threshold value and the measured value(s) is not greater than a second threshold value, or (c) a slow wave sleep state (N3) whenever the measured value(s) from the selected sensor(s) is greater than the first threshold value and the measured value(s) is greater than the second threshold value, and providing a notification of the classified behavioral state.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: May 16, 2023
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Vaclav Kremen, Brent M. Berry, Benjamin I. Brinkmann, Squire M. Stead, Gregory A. Worrell
  • Patent number: 11642513
    Abstract: A tremor suppression device includes a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region, and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; and apply neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: May 9, 2023
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Gaurav Sharma, Patrick Ganzer
  • Patent number: 11638826
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: May 2, 2023
    Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, Jr., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Patent number: 11623078
    Abstract: Devices and methods for non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode spaced from the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is positioned within the housing and operably coupled to the electrode, either wirelessly or via a lead or other wired connection. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises bursts each with a frequency from about 1 Hz to about 100 Hz, wherein each of the bursts comprises 2 pulses to 20 pulses.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: April 11, 2023
    Assignee: ELECTROCORE, INC
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 11623081
    Abstract: A subcutaneously implantable device is implantable into a body of a patient, and includes a prong and an electrode. The prong has a contact portion at or adjacent to a distal end thereof that is configured to contact an organ, a nerve, and/or a tissue of the patient. The prong is constructed to apply pressure to the organ, the nerve, and/or the tissue so as to maintain contact between the contact portion and the organ, the nerve, and/or the tissue without fixing the contact portion to the organ, the nerve, and/or the tissue. The electrode is provided at the contact portion of the prong, is configured to contact the organ, the nerve, and/or the tissue, and is electrically coupled or couplable with circuitry that is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to the organ, the nerve, and/or the tissue.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: April 11, 2023
    Assignee: Manicka Institute LLC
    Inventor: Yatheendhar D. Manicka
  • Patent number: 11623096
    Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: April 11, 2023
    Assignee: Medtronic, Inc.
    Inventors: Rene A. Molina, Scott R. Stanslaski, Jadin C. Jackson, Christopher L. Pulliam, Eric J. Panken, Michelle A. Case, Abbey Beuning Holt Becker
  • Patent number: 11612747
    Abstract: An apparatus includes an implant that includes circuitry and an elongate housing having a first half and a second half. A paresthesia-inducing electrode is disposed on the first half, and a blocking electrode is disposed on the second half. The circuitry has a first mode in which the circuitry simultaneously drives the paresthesia-inducing electrode to apply a paresthesia-inducing current having a frequency of 2-400 Hz, and the blocking electrode to apply a blocking current having a frequency of 1-20 kHz, and a second mode in which the circuitry drives the blocking electrode to apply the blocking current, but does not drive the paresthesia-inducing electrode to apply the paresthesia-inducing current. The implant is injectable into a subject along a longitudinal axis of the implant. Other embodiments are also described.
    Type: Grant
    Filed: August 4, 2021
    Date of Patent: March 28, 2023
    Assignee: BLUEWIND MEDICAL LTD.
    Inventors: Gur Oron, Bar Eytan, Eran Benjamin, Anton Plotkin, Yossi Gross
  • Patent number: 11609633
    Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to an Analytics Engine that receives one more signal files that include neural signal data of a user based on voltages detected by one or more electrodes on a set of headphones worn by a user. The Analytics Engine preprocesses the data, extracts features from the received data, and feeds the extracted features into one or more machine learning models to generate determined output that corresponds to at least one of a current mental state of the user and a type of facial gesture performed by the user. The Analytics Engine sends the determined output to a computing device to perform an action based on the determined output.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: March 21, 2023
    Assignee: Neurable, Inc.
    Inventors: Ramses Eduardo Alcaide, David Stanley, Dereck Padden, James Hamet, Adam Molnar, Jamie Alders, Jegan Candassamy, Arjun Daniel Srinivas
  • Patent number: 11607551
    Abstract: A neurostimulation system includes a programming control circuit and a user interface. The programming control circuit may be configured to generate a plurality of stimulation parameters controlling delivery of neurostimulation pulses according to one or more neurostimulation programs each specifying a pattern of the neurostimulation pulses. The user interface includes a display screen, a user input device, and a neurostimulation program circuit. The neurostimulation program circuit may be configured to allow for construction of one or more pulse trains (PTs) and one or more train groupings (TGs) of the one or more neurostimulation programs, and to allow for scheduling of delivery of the one or more neurostimulation programs, using the display screen and the user input device. Each PT includes one or more pulse blocks each including a plurality of pulses of the neurostimulation pulses. Each TG includes one or more PTs.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: March 21, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: David Ernest Wechter
  • Patent number: 11607549
    Abstract: Passive tissue biasing circuitry in an Implantable Pulse Generator (IPG) is disclosed to facilitate the sensing of neural responses by holding the voltage of the tissue to a common mode voltage (Vcm). The IPG's conductive case electrode, or any other electrode, is passively biased to Vcm using a capacitor, as opposed to actively driving such electrode to a prescribed voltage using a voltage source. Once Vcm is established, voltages accompanying the production of stimulation pulses will be referenced to Vcm, which eases neural response sensing. An amplifier can be used to set a virtual reference voltage and to limit the amount of current that flows to the case during the production of Vcm. Circuitry can be used to monitor the virtual reference voltage to enable sensing neural responses, and to set a compliance voltage for the current generation circuitry.
    Type: Grant
    Filed: May 18, 2021
    Date of Patent: March 21, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Goran N. Marnfeldt
  • Patent number: 11596792
    Abstract: A system, method, and apparatus for treating a medical condition by applying transcutaneous electrical stimulation to a target peripheral nerve of a subject. Electrical stimulation is applied to the peripheral nerve via a stimulation electrode pattern under closed-loop control in which EMG responses are monitored and used to adjust stimulation parameters. In response to detecting an unacceptable recording, electrical stimulation is applied to the peripheral nerve under open-loop control.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: March 7, 2023
    Assignee: AVATION MEDICAL, INC.
    Inventors: Alexandru Campean, Jeff A. Weisgarber, Mingming Zhang
  • Patent number: 11590352
    Abstract: Systems and methods for treating a patient's pain using ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods are disclosed. A representative method for treating a patient includes positioning an implantable signal delivery device proximate to a target location at or near the patient's spinal cord, and delivering an electrical therapy signal to the target location via the implantable signal delivery device, wherein the electrical therapy signal has a frequency in a frequency range of from about 1 kHz to about 100 kHz, and wherein the frequency is increased or decreased from a first value to a second value during delivery.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: February 28, 2023
    Assignee: Nevro Corp.
    Inventors: Dongchul Lee, Kerry Bradley, Kwan Yeop Lee
  • Patent number: 11590340
    Abstract: Systems, methods, and devices are provided herein providing electrical muscle stimulation (EMS). In some instances, an EMS device may be provided. The EMS device may be compact, light, and unobtrusive such that it can be used by a person going about his or her daily activities. In some instances, the EMS device may comprise additional sensors for increased functionality and may be capable of interacting with additional devices or platforms to provide a full-fledged EMS device capability.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: February 28, 2023
    Assignee: Therabody, Inc.
    Inventors: Alexey Pisarev, Vladimir Pisarev
  • Patent number: 11559250
    Abstract: The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.
    Type: Grant
    Filed: August 25, 2020
    Date of Patent: January 24, 2023
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventors: Joseph P. Giuffrida, Dustin A. Heldman
  • Patent number: 11554265
    Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: January 17, 2023
    Assignee: Saluda Medical Pty Ltd
    Inventors: John Louis Parker, James Hamilton Wah, Dean Michael Karantonis, Milan Obradovic, Robert Bruce Gorman