Abstract: A electrical treatment device (100) includes a band-like member (20), a first electrode portion (41), a second electrode portion (42), a first mark portion (31) configured to be aligned with a specific position of a right lower limb when the band-like member (20) is wrapped around the right lower limb such that the first electrode portion (41) is guided to a first target position and the second electrode portion (42) is guided to a second target position, and a second mark portion (32) configured to be aligned with a specific position of a left lower limb when the band-like member (20) is wrapped around the left lower limb such that the first electrode portion (41) is guided to a third target position and the second electrode portion (42) is guided to a fourth target position.

Abstract: A ground-effect footplate against which a user applies plantar force and moves their foot in 3D across all seven lower-extremity biomechanical axes to accomplish specific as well as global ambulatory objectives related to lower extremity performance improvement, injury prevention and rehabilitation. A device comprising at least one articulating leg connected to a ground-effect footplate and a surface for a user to position against. The device can be used in conjunction with software to create virtual ambulatory environments that mimic GRFVs and cause moments of force that initiate muscular activations that substantially mimic human ambulation, and can couple those movements with non-functional movements in order to improve ROM, speed, strength, and proprioception.

Abstract: Systems and methods of generating and applying a synthetic neuromodulatory signal are described. A subject may be put under a particular condition that causes an effect in the subject. While the subject is under the condition, a recording of neurogram signals derived from the condition can be made from the subject. For example, neuronal signals traveling on the vagus nerve of the subject may be monitored and recorded. The neurogram may then be used to create a synthetic neuromodulatory signal that can be administered to a user. When the synthetic neuromodulatory signal is administered to the user, the user may experience the same effect as the subject that had been placed in the condition, even though the user was never put under the same condition.

Abstract: A portable electrical stimulation device is disclosed. In one aspect, the device includes a pair of electrodes configured to be electrically coupled to a user and a wave generator configured to provide an electrical signal to the user via the pair of electrodes. The wave generator is further configured to generate the electrical signal at one of a plurality of levels. Each of the plurality of levels is defined by at least a frequency, a peak voltage, and a peak current. For each of the levels the frequency is in a range of about 50 Hz-about 500 Hz, the peak voltage is in a range of about 40 V-about 250 V, the peak current is in a range of about 25 mA-about 150 mA, and the frequency and the peak voltage have a generally inverse relationship.

Abstract: A stimulation therapy system dynamically modifies therapy intensity based on measured neurotransmitter levels. In some examples, the system delivers, via an electrode implanted in a brain of a patient and stimulation circuitry, an electrical stimulus; monitors an electrical current generated by the stimulation circuitry to deliver the electrical stimulus; determines, based on the electrical current, a value representative of a concentration of dopamine in the brain of the patient; determines, based on the value representative of the concentration of dopamine, a value for one or more stimulation parameters that at least partially define electrical stimulation therapy; and delivers, via the electrode, the electrical stimulation therapy.

Abstract: Apparatus for transcutaneous electrical nerve stimulation in humans, the apparatus comprising: a housing; a stimulation unit mounted within the housing for electrically stimulating nerves; an electrode array releasably mounted to the housing and connectable to the stimulation means, the electrode array comprising a plurality of electrodes for electrical stimulation of nerves; a control unit mounted to the housing and electrically connected to the stimulation unit for controlling at least one characteristic of the stimulation unit; a monitoring unit mounted to the housing and electrically connected to the stimulation unit for monitoring at least one characteristic of the stimulation unit; a user interface unit mounted to the housing and electrically connected to the control unit for controlling the stimulation unit; a display unit mounted to the housing and electrically connected to the control unit and the monitoring unit for displaying the status of the stimulations unit; and a strap attached to the housing;

Abstract: A device, system and method for increasing air intake by a subject is described. The device includes a vibration motor and a control unit for controlling vibrational motion output by the vibration motor. The methods include positioning the vibration motor on one or more limbs of a subject, and stimulating nerves in the limbs via the generated vibrational motion, whereby the stimulated nerve signals the brain to increase breathing rate or air intake by the subject. Accordingly, embodiments of the device activate nerve fibers that carry kinesthetic cues from the limbs in a pattern that simulates normal limb motion, and thus triggers inherent reflexes that increase ventilation in response to such motion.

Abstract: A locking device including a first frame including an insert hole and a first magnetic body, a second frame including an insert recess communicating with the insert hole, and a second magnetic body disposed to face the first magnetic body with a polarity opposite to a polarity of the first magnetic body, and an insert member including a slider inserted into the insert hole and configured to slide relative to the first frame, and a third magnetic body disposed on one side of the slider is provided.

Abstract: A gait management apparatus applies stimulation to a user suffering from a neurological disease (such as Parkinson's Disease) gait dysfunction. Motion sensors are arranged to be worn by a patient, and electrical stimulation electrodes are on the legs for stimulation. A controller receives motion sensing signals, and processes these signals to generate stimulation signals for operation of the electrodes to stimulate limb movement upon detection of a gait abnormality. There may be a user actuator for user actuation of electrical stimulation, and the inputs may be a series of taps. The controller may provide signals to prevent occurrence of freezing of gait when it senses that a patient is walking or has an intention to walk. Also, it may apply stimulation at an intensity level which is insufficient for functional muscle stimulation but sufficiently high to trigger activation of efferent nerves.

Abstract: A subcutaneously implantable device is implantable into a body of a patient, and includes a prong and an electrode. The prong has a contact portion at or adjacent to a distal end thereof that is configured to contact an organ, a nerve, and/or a tissue of the patient. The prong is constructed to apply pressure to the organ, the nerve, and/or the tissue so as to maintain contact between the contact portion and the organ, the nerve, and/or the tissue without fixing the contact portion to the organ, the nerve, and/or the tissue. The electrode is provided at the contact portion of the prong, is configured to contact the organ, the nerve, and/or the tissue, and is electrically coupled or couplable with circuitry that is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to the organ, the nerve, and/or the tissue.

Abstract: The disclosure provides a soak tester apparatus for testing an implantable enclosure having an impedance engine, a multiplexer and a removably attached cartridge, which cartridge has a plurality of threads, comprising a Faraday cage housing; a receptacle disposed within the Faraday cage housing, wherein the receptacle is configured to host an implantable enclosure having an impedance engine, a multiplexer and a removably attached cartridge, which cartridge has a plurality of threads; and a pigtail disposed within the Faraday cage housing having a charging coil configured to power the implantable enclosure.

Abstract: A tissue stimulation device comprising: a source; a control unit; a decoupled output stage circuit connected to the source and the control unit; a signal generator connected to the input of the decoupled output stage circuit and the control unit; an analog demultiplexer connected to the output stage circuit decoupled by a PE signal and an out signal, the analog demultiplexer is connected to the control unit, and a transducer array is connected to the output of the analog demultiplexer; wherein the control unit selects the output of the analog demultiplexer that allows switching of the PE and out signals to activate the transducers in the transducer array to stimulate tissue.

Abstract: An example of a neurostimulation system may include a programming control circuit and a stimulation control circuit. The programming control circuit may be configured to program a stimulation device for delivering the neurostimulation according to a stimulation program specifying a present stimulation field set including stimulation field(s) each defined by a set of active electrodes selected from a plurality of electrodes. The stimulation control circuit may be configured to determine the stimulation program and may include field programming circuitry that may be configured to set the present stimulation field set to an initial stimulation field set specifying stimulation fields allowing for the delivery of the neurostimulation to produce an intended effect and to identify an optimal stimulation field set that satisfies one or more optimization criteria by removing stimulation field(s) from the initial stimulation field set.

Abstract: An electronic device tracks, for a user performing a target acquisition movement within a 3D space, movement parameters of a plurality of input devices of the user. The electronic device predicts, for the user, a region of interest within the 3D space, based on the movement parameters. The region of interest includes a plurality of targets in close proximity. The electronic device predicts an endpoint of the target acquisition movement, within the region of interest. In some embodiments, the plurality of input devices includes an eye tracking input device, each input device corresponds to a predefined input device type, and the movement parameters include gaze data from the eye tracking input device. In some embodiments, input devices includes an eye tracking input device, a head-mounted display, and a hand-held controller, and the user's eye, hand, and head movements are coordinated.

Abstract: A behavioral state of a brain is classified by automatically selecting one or more sensors based on the signals received from each sensor and one or more selection criteria using one or more processors, calculating at least one measured value from the signal(s) of the selected sensor(s), classifying the behavioral state as: (a) an awake state whenever the measured value(s) for the selected sensor(s) is lower than a first threshold value, (b) a sleep state (N2) whenever the measured value(s) for the selected sensor(s) is equal to or greater than the first threshold value and the measured value(s) is not greater than a second threshold value, or (c) a slow wave sleep state (N3) whenever the measured value(s) from the selected sensor(s) is greater than the first threshold value and the measured value(s) is greater than the second threshold value, and providing a notification of the classified behavioral state.

Abstract: A tremor suppression device includes a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region, and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; and apply neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.

Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.

Abstract: Devices and methods for non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode spaced from the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is positioned within the housing and operably coupled to the electrode, either wirelessly or via a lead or other wired connection. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises bursts each with a frequency from about 1 Hz to about 100 Hz, wherein each of the bursts comprises 2 pulses to 20 pulses.

Abstract: A subcutaneously implantable device is implantable into a body of a patient, and includes a prong and an electrode. The prong has a contact portion at or adjacent to a distal end thereof that is configured to contact an organ, a nerve, and/or a tissue of the patient. The prong is constructed to apply pressure to the organ, the nerve, and/or the tissue so as to maintain contact between the contact portion and the organ, the nerve, and/or the tissue without fixing the contact portion to the organ, the nerve, and/or the tissue. The electrode is provided at the contact portion of the prong, is configured to contact the organ, the nerve, and/or the tissue, and is electrically coupled or couplable with circuitry that is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to the organ, the nerve, and/or the tissue.

Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

Abstract: An apparatus includes an implant that includes circuitry and an elongate housing having a first half and a second half. A paresthesia-inducing electrode is disposed on the first half, and a blocking electrode is disposed on the second half. The circuitry has a first mode in which the circuitry simultaneously drives the paresthesia-inducing electrode to apply a paresthesia-inducing current having a frequency of 2-400 Hz, and the blocking electrode to apply a blocking current having a frequency of 1-20 kHz, and a second mode in which the circuitry drives the blocking electrode to apply the blocking current, but does not drive the paresthesia-inducing electrode to apply the paresthesia-inducing current. The implant is injectable into a subject along a longitudinal axis of the implant. Other embodiments are also described.

Abstract: Passive tissue biasing circuitry in an Implantable Pulse Generator (IPG) is disclosed to facilitate the sensing of neural responses by holding the voltage of the tissue to a common mode voltage (Vcm). The IPG's conductive case electrode, or any other electrode, is passively biased to Vcm using a capacitor, as opposed to actively driving such electrode to a prescribed voltage using a voltage source. Once Vcm is established, voltages accompanying the production of stimulation pulses will be referenced to Vcm, which eases neural response sensing. An amplifier can be used to set a virtual reference voltage and to limit the amount of current that flows to the case during the production of Vcm. Circuitry can be used to monitor the virtual reference voltage to enable sensing neural responses, and to set a compliance voltage for the current generation circuitry.

Abstract: A neurostimulation system includes a programming control circuit and a user interface. The programming control circuit may be configured to generate a plurality of stimulation parameters controlling delivery of neurostimulation pulses according to one or more neurostimulation programs each specifying a pattern of the neurostimulation pulses. The user interface includes a display screen, a user input device, and a neurostimulation program circuit. The neurostimulation program circuit may be configured to allow for construction of one or more pulse trains (PTs) and one or more train groupings (TGs) of the one or more neurostimulation programs, and to allow for scheduling of delivery of the one or more neurostimulation programs, using the display screen and the user input device. Each PT includes one or more pulse blocks each including a plurality of pulses of the neurostimulation pulses. Each TG includes one or more PTs.

Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to an Analytics Engine that receives one more signal files that include neural signal data of a user based on voltages detected by one or more electrodes on a set of headphones worn by a user. The Analytics Engine preprocesses the data, extracts features from the received data, and feeds the extracted features into one or more machine learning models to generate determined output that corresponds to at least one of a current mental state of the user and a type of facial gesture performed by the user. The Analytics Engine sends the determined output to a computing device to perform an action based on the determined output.

Abstract: A system, method, and apparatus for treating a medical condition by applying transcutaneous electrical stimulation to a target peripheral nerve of a subject. Electrical stimulation is applied to the peripheral nerve via a stimulation electrode pattern under closed-loop control in which EMG responses are monitored and used to adjust stimulation parameters. In response to detecting an unacceptable recording, electrical stimulation is applied to the peripheral nerve under open-loop control.

Abstract: Systems and methods for treating a patient's pain using ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods are disclosed. A representative method for treating a patient includes positioning an implantable signal delivery device proximate to a target location at or near the patient's spinal cord, and delivering an electrical therapy signal to the target location via the implantable signal delivery device, wherein the electrical therapy signal has a frequency in a frequency range of from about 1 kHz to about 100 kHz, and wherein the frequency is increased or decreased from a first value to a second value during delivery.

Abstract: Systems, methods, and devices are provided herein providing electrical muscle stimulation (EMS). In some instances, an EMS device may be provided. The EMS device may be compact, light, and unobtrusive such that it can be used by a person going about his or her daily activities. In some instances, the EMS device may comprise additional sensors for increased functionality and may be capable of interacting with additional devices or platforms to provide a full-fledged EMS device capability.

Abstract: The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: The invention relates to a system (1) for stimulating renal nerves of a renal artery of a subject (3). The system comprises a stimulation device (12, 17, 28) for stimulating the renal nerves, a measuring unit (20) for measuring the blood pressure and/or the heart rate of the subject at at least two times, wherein at least one of these times is during or after the stimulation of the renal nerves, and a subject suitability determination unit (14) for determining whether the subject is suitable for a renal sympathetic denervation procedure based on the measured blood pressure and/or the measured heart rate. The invention allows therefore for a preselection of subjects which are suitable for a renal sympathetic denervation procedure.

Abstract: Device/system that provides pain relief by delivering stimulation that neither generates action potentials nor completely blocks neural transmission (in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve) to alter the frequency of physiologically generated neural transmission.

Abstract: An apparatus of muscle treatment may have a plurality of treatment modes and may generate a specific motion of a human body simultaneously or with an interval for muscles anatomically distinguished and related to each other, thereby being able to simultaneously strength the muscles related to each other. Since muscles are treated in accordance with a transmitting pattern of RF energy enabling composite motions of a human body, thereby being able to increase the treatment effect.

Abstract: The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

Abstract: Various embodiments concern delivering electrical stimulation to the brain at a plurality of different levels of a stimulation parameter and sensing a bioelectrical response of the brain to delivery of the electrical stimulation for each of the plurality of different levels of the stimulation parameter. A suppression window of the stimulation parameter can be identified as having a suppression threshold as a lower boundary and an after-discharge threshold as an upper boundary based on the sensed bioelectrical responses. A therapy level of the stimulation parameter can be set for therapy delivery based on the suppression window. The therapy level of the stimulation parameter may be set closer to the suppression threshold than the after-discharge threshold within the suppression window. Data for hippocampal stimulation demonstrating a suppression window is presented.

Abstract: A control system for a movement reconstruction and/or restoration system for a patient, comprising a sampling module configured and arranged to sample signals describing directly and/or indirectly motion at a sampling rate of at least 50 Hz; at least one stimulation system configured and arranged to provide stimulation for movement reconstruction and/or restoration to the patient; a prediction module configured and arranged to provide a prediction of at least a next movement, especially movement stage and/or sequence, to reduce latency and to synchronize stimulation to the movement phase, wherein the control system further comprises at least one controller, the controller being configured and arranged to provide stimulation control signals to the stimulation system on the basis of the information obtained by the sampling module and the prediction provided by the prediction module.

Abstract: Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.

Abstract: Artifacts due to delivery of an electrical signal (e.g., for neural stimulation or nerve block) can be eliminated from neural recordings. An activating stimulus (AS) can be applied by at least one neural electrode located at a first position within a body or a preparation proximal to a neural structure. The AS includes an electrical waveform configured to affect (e.g., stimulate or block) conduction in the neural structure. A counter stimulus (CS) can be applied by at least one electrode located at a second position within the body or the preparation remote from the neural structure. The CS includes an electrical waveform configured with a timing parameter and an amplitude parameter selected based on a feature of the AS. Artifacts due to the AS can be blocked by the CS during the neural recordings.

Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.

Abstract: An electrical stimulation system includes at least one electrical stimulation lead, each of the at least one electrical stimulation lead including a plurality of stimulation electrodes; and a processor coupled to the lead and configured to perform actions, including: directing delivery of at least one electrical pulse through at least one of the stimulation electrodes of the at least one electrical stimulation lead to tissue of a patient; and directing discrete or intermittent measurement of an electrical characteristic of the tissue using at least one of the stimulation electrodes of the at least one electrical stimulation lead during, and after, delivery of the at least one electrical pulse to the tissue of the patient.

Abstract: The present disclosure describes a system, method and software applications for predicting the KAM of a subject for a plurality of gait cycles of a subject. At least one sensor attachable adjacent to the ankle of at least one leg of the subject provides accelerometer and gyroscopic data for the plurality of gait cycles. A processing means receives subject parameters and accelerometer and gyroscopic data from the at least one sensor for evaluation by a neural network of predicted KAM values for the plurality of gait cycles of the subject. The neural network is configured via determining KAM values for each of the plurality of subjects from measurements during a plurality of gait cycles and other parameters.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.

Abstract: An electrical stimulation indoor bike includes a stationary bicycle; an electrical stimulation unit connected to the stationary bicycle either with wire or without wire, and including an electrode pad for applying electrical stimulation to a user's body; and a control unit to control electrical stimulation of the electrical stimulation unit in accordance with an exercise mode of the stationary bicycle. By the electrical stimulation indoor bike, a variety of electrical stimulation according to pedal movement is applied to a body through an indoor bike connected with a low-frequency stimulator, thereby maximizing exercise effect.

Abstract: A method for configuring an electroanalgesia and electrotherapy apparatus using wireless control, with multiple stimulators, particularly used in the segment of pain control and aid in postoperative tissue repair and reduction of measures and body weight. According to the embodiments, a user with electrodes generically distributed simultaneously in several parts of the body, where at the pain site the frequency is from 80 Hz to 300 Hz or 1000 Hz and then to a range of 15 Hz to 35 Hz or among 0.5 Hz and 10 Hz on that electrode, and at distant points, for example, in upper or lower limbs the frequency is from 0.5 Hz to 10 Hz and, so the person can be submitted to this analgesia procedure, according to the pre-determined frequencies, pulse width and pulse form already pre-defined.

Abstract: The occurrence of negative consequences (e.g., painful tetanic muscle contractions) associated with the onset response associated with kilohertz frequency alternating current (KHFAC) electrical nerve block can be reduced by fatiguing a muscle (through depletion of neurotransmitters at the neuromuscular junction, within a second) before applying KHFAC electrical nerve block to a nerve associated with the muscle. The nerve can first be stimulated with an electrical signal for a first time period to fatigue the muscle. Then, immediately following the first time period (while the muscle is fatigued), a blocking electrical signal (e.g., a kilohertz frequency alternating current waveform) can be applied to the nerve to create a localized nerve block.

Abstract: A treatment assembly can have an inner layer having an inner surface and an outer surface and defining a plurality of openings extending therethrough. The treatment assembly can further comprise a plurality of plates, each plate being at least partially received within a respective opening of the plurality of openings of the inner layer. The treatment assembly can further comprise treatment circuitry comprising a cable having a plurality of electrical leads and a plurality of lead ends, each electrical lead being electrically connected to a respective lead end of the plurality of lead ends. A cover layer can be attached to the outer surface of the inner layer and overlie the plurality of lead ends of the cable. The plurality of lead ends can be in contact with respective plates of the plurality of plates to define a plurality of electrodes.

Abstract: The present disclosure provides electroporation systems and methods of preconditioning tissue for electroporation therapy. An electroporation generator includes an electroporation circuit, a preconditioning circuit, and a controller. The electroporation circuit is configured to be coupled to a catheter for delivering the electroporation therapy to target tissue of the patient. The electroporation circuit is further configured to transmit an electroporation signal through the catheter. The preconditioning circuit is configured to be coupled to a preconditioning electrode for stimulating skeletal muscle tissue of the patient. The preconditioning circuit is further configured to transmit a preconditioning signal to the preconditioning electrode.

Abstract: Examples of the present disclosure are related to devices in the field of transcutaneous electrical nerve stimulation and neuromuscular electrical stimulation. More specifically, embodiments are related to devices that are configured to automatically detect the stimulation intensity range and the motor point to generate a high efficiency, low intensity electrical stimulation treatment.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: A patient's healthcare experience may be enhanced utilizing a system that automatically recognizes the patient based on one or more images of the patient and generates personalized medical assistance information for the patient based on electronic medical records stored for the patient. Such electronic medical records may comprise imagery data and/or non-imagery associated with a medical procedure performed or to be performed for the patient. As such, the imagery and/or non-imagery data may be incorporated into the personalized medical assistance information to provide positioning and/or other types of diagnostic or treatment guidance to the patient or a service provider.