Abstract: An external device includes a communication circuit, a programming interface including a display, and a processor. The processor includes a parameter analyzer to apply a rule to a combination of operating parameter values of the IMD to determine operating parameter interaction. The display includes a first warning that is displayed when the parameter analyzer determines that a combination of operating parameter values entered via the programming interface is not allowed, and a second warning that is displayed when the parameter analyzer determines that a combination of operating parameters values entered via the programming interface is allowable but not recommended. The processor is configured to program the operating parameter values associated with the second warning into the IMD only after a user acknowledgement of the second warning is received from a user via the programming interface.

Abstract: A control system for use with a neurostimulator comprises a user interface for receiving an input from a user and a controller. The user interface has a first control and a second control. The controller is configured for, in response to actuating the first control, operating the neurostimulation control system in a PNFS programming mode, and for, in response to actuating the second control, operating the neurostimulation control system in a PNS programming mode. A method of providing therapy to a patient comprises initially conveying pulsed electrical current at a pulse width into a peripheral tissue region of the patient to create a side effect via stimulation of one of a nerve ending and neural axon, and subsequently conveying pulsed electrical current at an adjusted pulse width into the peripheral tissue region to create a therapeutic effect via stimulation of the other one of the nerve ending and neural axon.

Abstract: An interactive representation of electrostimulation electrodes or vectors can be provided, such as for configuring combinations of electrostimulation electrodes. In an example, electrodes or test parameters can be presented graphically or in a table. A user interface can be configured to receive user-input designating electrode combinations or vectors for test or for use in programming an implantable or ambulatory medical device. The interface can be used to indicate suggested electrode combinations or vectors in response to a first selection of an electrode. Tests can be performed on electrode combinations and vectors, and the results of the tests can be presented to a user using the interactive representation. In an example, test results can be analyzed by a processor and optionally used to program an implantable or ambulatory medical device.

Abstract: In general, the invention is directed to a system with a fail-safe mode for remote programming of medical devices, such as implantable medical devices (IMDs). During a remote programming session, an adverse event, such as a programming session failure, may prevent proper completion of a programming or result in improper programming due to data corruption or other factors. If a programming session is not completed correctly, the IMD is susceptible to improper operation, possibly exposing a patient to delivery of unnecessary or inappropriate therapies. A fail-safe mode reduces the likelihood of improper operation following a programming session failure. The fail-safe mode defines one or more fail-safe operations designed to preserve proper operation of the IMD. In some embodiments, the fail-safe operations include notifying a person concerning the failure of the programming session, modifying programming parameters within the implantable medical device, and delivering a therapy to a patient.

Abstract: Implantable stimulation devices are provided. Aspects of the devices include a multiplexed multi-electrode component configured for neural stimulation. The multiplexed multi-electrode component includes two or more individually addressable satellite electrode structures electrically coupled to a common conductor. The satellite structures include a hermetically sealed integrated control circuit operatively coupled to one or more electrodes. Also provided are methods of manufacturing wherein the application of laser welding is avoided in forming the satellite electrode structures and an integrated control circuit thereof is thereby shielded from mechanical stress during satellite manufacture. Additionally provided are systems that include the devices of the invention, as well as methods of using the systems and devices in a variety of different applications.

Abstract: Wet-tantalum capacitors used in a medical device are charged to and maintained at a maintenance voltage between full energy charges so that deformation in the wet-tantalum capacitor is substantially inhibited.

Abstract: A device that programs a medical device includes a display and a user input device. The device displays a graphical representation of a plurality of electrodes on a medical lead implanted in the patient, and displays an active electrode template at a first position relative to the graphical representation of the electrodes. A processor of the device receives input dragging the active electrode template. In response to the input dragging the active electrode template, the processor adjusts at least one parameter of electrical stimulation delivered to the patient via the lead based on the position of the active electrode template relative to the graphical representation of the electrodes on the medical lead.

Abstract: A lead for providing electrical stimulation of patient tissue includes a distal lead element, at least two proximal lead elements, and a junction coupling the distal lead element to each of the at least two proximal lead elements. The distal lead element includes a plurality of electrodes and a plurality of conductive wires coupled to the plurality of electrodes and extending along a longitudinal axis of the distal lead element. Each of the at least two proximal lead elements includes a plurality of terminals and a plurality of conductive wires coupled to the plurality of terminals and extending along a longitudinal axis of the proximal lead element. The junction includes a circuit arrangement electrically coupling each of the conductive wires of the distal lead element to at least one of the conductive wires of at least one of the at least two proximal lead elements.

Abstract: A method and apparatus for diagnosing and treating neural dysfunction is disclosed. This device has the capability of delivering the therapeutic electrical energy to more than one treatment electrode simultaneously. In another exemplary embodiment, this device can perform EMG testing both before and after the therapeutic energy has been delivered, to assess whether the target nerve was successfully treated. In another embodiment, the device has the capability to record and store sensory stimulation thresholds both before and after treatment is described, which allows the clinician to accurately determine whether the target nerve has been desensitized. Energy control may achieved by simultaneously comparing the tip temperature of each treatment electrode to a set temperature selected by the operator, and regulating the therapeutic energy output to maintain the set temperature.

Abstract: The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination.

Abstract: The disclosure is directed to techniques for shifting between two electrode combinations. An amplitude of a first electrode combination is incrementally decreased while an amplitude of a second, or subsequent, electrode combination is concurrently incrementally increased. Alternatively, an amplitude of the first electrode combination is maintained at a target amplitude level while the amplitude of the second electrode combination is incrementally increased. The stimulation pulses of the electrode combinations are delivered to the patient interleaved in time. In this manner, the invention provides for a smooth, gradual shift from a first electrode combination to a second electrode combination, allowing the patient to maintain a continual perception of stimulation. The shifting techniques described herein may be used during programming to shift between different electrode combinations to find an efficacious electrode combination.

Abstract: A method and neurostimulation control system for programming electrodes disposed adjacent tissue of a patient. The electrodes are initially assigned to a plurality of electrode subsets to be evaluated. A pair of immediately neighboring ones of the electrode subsets is determined, and merged into a new electrode subset that includes all electrodes in the pair of immediately neighboring electrode subsets. The new electrode subset is included within the plurality of electrode subsets to be evaluated, while the pair of immediately neighboring electrode subsets is excluded from the plurality of electrode sets to be evaluated. These steps are repeated until all the electrode subsets have been merged into a single electrode subset. A clustering relationship of the electrodes is identified, and the electrodes are programmed based on the identified clustering relationship of the electrodes.

Abstract: In general, the disclosure describes techniques for providing conditional electrical stimulation to a patient for pelvic health. An implantable medical device (IMD) may adjust the delivery cycle of the electrical stimulation applied to a patient in response to receiving a delivery cycle parameter associated with one or more of the following: a time in a time schedule, a control device output from a control device, and physiological information from a physiological information sensing device. As an example, the IMD may monitor a status of one or more inputs of the IMD and adjust the delivery cycle of the electrical stimulation applied to the patient based on the status of the input(s).

Abstract: An implantable medical device delivers neurostimulation therapy to a patient according to a parameter set. A parameter set may consist of a number of programs that are delivered substantially simultaneously. When programming the implantable medical device for the patient, a clinician programmer may maintain a session log for the patient that includes a listing of programs delivered to the patient and rating information provided by a clinician and the patient for programs of the list. The listing may be ordered according to the rating information in order to facilitate the selection of programs for a parameter set. A program library that may include particularly effective programs organized according to a directory structure may be stored in a memory. One or both of the implantable medical device and a patient programmer may store usage information that provides an objective assessment of therapy use by the patient, and allows a clinician to later improve the therapy based on the usage information.

Abstract: A method, electrical tissue stimulation system, and programmer for providing therapy to a patient are provided. Electrodes are placed adjacent tissue (e.g., spinal cord tissue) of the patient, electrical stimulation energy is delivered from the electrodes to the tissue in accordance with a defined waveform, and a pulse shape of the defined waveform is modified, thereby changing the characteristics of the electrical stimulation energy delivered from the electrode(s) to the tissue. The pulse shape may be modified by selecting one of a plurality of different pulse shape types or by adjusting a time constant of the pulse shape.

Abstract: An external defibrillator is customized for at least one person, i.e., an anticipated patient, through creation of a profile for the anticipated patient that allows the defibrillator and users of the defibrillator to provide customized treatment to the patient. The profile may include treatment parameters for the anticipated patient, such as defibrillation therapy parameters selected for the patient. The profile may also include a baseline recording of a physiological parameter of the patient, and medical history and personal information regarding the patient. In some embodiments, the external defibrillator stores a profile for each of one or more anticipated patients within a memory. In other embodiments, a profile for an anticipated patient is stored within a medium associated with that anticipated patient. The medium may, for example, be a removable medium for external defibrillators.

Abstract: A tissue stimulation system and computer software and method of monitoring a neurostimulation lead having a plurality of electrodes implanted within a patient (e.g., adjacent the spinal cord) is provided. Neurostimulation lead models are provided, each of which includes estimated electrical parameter data (e.g., electrical field potential data) corresponding to a predetermined position of the neurostimulation lead. Electrical energy is transmitted to or from the electrodes, and electrical parameter data (e.g., electrical field potential data) is measured in response to the transmitted electrical energy. The measured electrical parameter data is compared with the estimated electrical parameter data of each of the neurostimulation lead models, and a position of the neurostimulation lead is determined based on the comparison.

Abstract: The invention relates to a stimulation device for creating complex or multi-purpose tissue stimulation. Many typical stimulation devices suffer from deficiencies in providing complex stimulation patterns. Using a circuitry operable or programmable to repeat and skip stimulation settings, a complex stimulation set may be created. The repeating and skipping functionality may be implemented in hardware or software. In this manner, complex stimulations may be derived from simple circuitries. Furthermore, these stimulations may be used to treat pain, stimulate bone growth, and control motor disorders, among others.

Abstract: An implantable microstimulator configured for implantation beneath a patient's skin for tissue stimulation to prevent and/or treat various disorders, uses a self-contained power source. Periodic or occasional replenishment of the power source is accomplished, for example, by inductive coupling with an external device. A bidirectional telemetry link allows the microstimulator to provide information regarding the system's status, including the power source's charge level, and stimulation parameter states. Processing circuitry automatically controls the applied stimulation pulses to match a set of programmed stimulation parameters established for a particular patient. The microstimulator preferably has a cylindrical hermetically sealed case having a length no greater than about 27 mm and a diameter no greater than about 3.3 mm. A reference electrode is located on one end of the case and an active electrode is located on the other end.

Abstract: A telemetry system is presented for enabling radio-frequency (RF) communications between an implantable medical device and an external device in a manner which reduces the power requirements of the implantable device by duty cycling its RF circuitry. A wakeup scheme for the implantable device is provided in which the external device transmits a data segment containing a repeating sequence of special wakeup characters in order to establish a communications session with the implantable device. The wakeup scheme may be designed to operate in the context of a handshaking protocol for collision avoidance.

Abstract: A system and method for selection of stimulation parameters for Deep Brain Stimulation (DBS) may include a processor that displays in a display device and in relation to a displayed model of a leadwire including model electrodes, a current field corresponding to a first stimulation parameter set, provides a user interface for receipt of user input representing a shift of the current field, in response to the user input, moves, in the display device, the current field with respect to the displayed model, determines a second stimulation parameter set that results in the moved current field, and outputs the second stimulation parameter set and/or sets a stimulation device with the second stimulation parameter set, where the stimulation device is configured for performing a stimulation using the leadwire in accordance with the second stimulation parameter set.

Abstract: Various neural stimulator embodiments comprise controller circuitry, neural stimulation output circuitry, sensor circuitry and a memory. The neural stimulation output circuitry is configured to deliver the neural stimulation. The controller circuitry is configured to control stimulation parameters of the neural stimulation delivered by the neural stimulation output circuitry. The sensor circuitry, including at least one sensor, is configured to sense a response to the neural stimulation. The controller is configured to communicate with the sensor circuitry. The memory has instructions stored therein, operable on by the controller circuitry.

Abstract: A system for providing stimulation current in implantable medical devices is provided. One aspect of this disclosure relates to an apparatus including a power supply terminal adapted to be connected to a power supply. The apparatus embodiment also includes circuitry connected to the power supply terminal and adapted to detect a parameter dependent on tissue/electrode impedance. The apparatus embodiment further includes a current output pulse generator adapted to deliver electrical therapy. The current generator includes an adjustable compliance voltage source connected to the power supply terminal. The compliance voltage source has a programmable amplitude and is adapted to provide different potentials for different tissue/electrode interface impedances. According to various embodiments, the apparatus embodiment also includes at least one stimulating electrode, and the current generator is adapted to deliver electrical therapy using the electrode. Other aspects and embodiments are provided herein.

Abstract: Techniques are described, for medical devices that deliver electrical stimulation therapy, for controlling a transition from an initial stimulation location or initial stimulation shape to a user-specified target stimulation location or target stimulation shape in order to limit the rate of change of stimulation. One example method includes receiving, via a programmer for an electrical stimulator, user input indicating a target stimulation zone, and controlling the electrical stimulator to transition electrical stimulation from an initial stimulation zone to the target stimulation zone via one or more intermediate stimulation zones.

Abstract: A system and method for electrically stimulating the heart muscle to improve heart function requires identifying a site in the venous system adjacent a sympathetic nerve. An electrode is then positioned at the site to electrically stimulate the nerve. In turn, this stimulation releases norepinephrine from the nerve to improve heart muscle contraction.

Abstract: The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm whose presence, absence, or baseline change is associated with impending disease, and comparing such rhythm to baseline circadian rhythm prediction criteria. Other chronobiological rhythms beside circadian may also be used. The baseline prediction criteria may be derived using one or more past physiological process observation of the subject or population of subjects in a non-disease health state. The prediction processing may be performed by the at least one implantable device or by an external device in communication with the implantable device. Systems and methods for invoking a therapy in response to the health state, such as to prevent or minimize the consequences of predicted impending heart failure, are also discussed.

Abstract: A mechanism for transferring energy from an external power source to an implantable medical device is disclosed. A sensor may be used to measure a parameter that correlates to a temperature of the system that occurs during the transcutaneous coupling of energy. For example, the sensor may measure temperature of a surface of an antenna of the external power source. The measured parameter may then be compared to a programmable limit. A control circuit such as may be provided by the external power source may then control the temperature based on the comparison. The programmable limit may be, for example, under software control so that the temperature occurring during transcutaneous coupling of energy may be modified to fit then-current circumstances.

Abstract: A system and method for communicating data and signals through the Medical Implant Communication Service Band using a repeater or base station in the proximity to an implantable device within a patient is disclosed. In a preferred embodiment, the device is capable for early detection and monitoring of congestive heart failure in a patient. Impedance measurements, or other health parameters depending on the type of implantable device or sensor used, are sent using a bi-directional low-power radio operating in the MICS band to a nearby base station which may provide signal processing and analysis. The base station may have an interface to one or more communications networks to connect to a remote location. The system and method of the present invention permits a healthcare professional to monitor an ambulatory patient's condition at a remote location and to program the implanted device.

Abstract: A treatment system includes a regulator implanted within a patient, a computing device storing at least one patient database associated with the patient in whom the regulator is implanted, and a data transfer device. The data transfer device provides bidirectional communication (e.g., voice communication) and a data exchange (e.g., a treatment history, a patient database, and operational instructions) between the regulator and the computing device. A programmer can obtain patient reports and/or default treatment values from the computing device based on the data exchange.

Abstract: A new apparatus of pure digital medical amplifier used for clinical and non-clinical biomedical signal acquisition purposes is disclosed, which include: multiple single-stage amplification buffers connected to biomedical signal inputs for receiving and buffering various biomedical and reference signals, one or more high resolution analog-to-digital converter whose analog inputs connected to the output of said buffers for digitizing biomedical signals, one or more digital signal controller whose inputs/outputs are connected to said buffers and analog-to-digital converters for receiving the digitized biomedical signal data and controlling the processing and output of said digitized biomedical signal data according to preset control program or user's commands.

Abstract: A programmer allows a clinician to identify desirable combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The clinician may create neurostimulation therapy programs that include identified desirable electrode combinations. In some embodiments, the clinician may use the programmer to select a program, such as a program identified during a neurostimulation programming session, and direct the programmer to replicate the selected program. The programmer may change one or more parameters of the selected program, such as pulse amplitude or duty cycle, when generating the copy of the selected program.

Abstract: A neurostimulation array comprising a first implantable neurostimulator storing a first identification code in a non-volatile memory and responding to communications including said first identification code, a second implantable neurostimulator storing a second identification code in a non-volatile memory and responding to communications including said second identification code, and a polymer connector attached to said first implantable neurostimulator and said second implantable neurostimulator, thereby forming a neurostimulation array.

Abstract: The electrical nerve stimulation unit in accordance with the present invention generally includes a housing, an input panel, a display panel, a controller, a first channel output, a second channel output, and a power system. While the device is generally described in terms of use as a TENS unit, it must be noted that other nerve stimulation applications for the device are envisioned as well. The myriad of intelligent and proactive programmable software functions and features of the present invention are executed on the controller's microprocessor. For instance, open lead monitoring, soft recovery implementation, compliance monitoring, and enhanced power management are all controlled and monitored through the interfacing of the processor with the various devices and hardware on the unit's hardware platform.

Abstract: A method and external control device for operating a plurality of electrode leads implanted within the tissue of a patient. A virtual electrode leads in a reference lead configuration are displayed. One of the virtual electrode leads is selected. The selected virtual electrode lead is dragged, and the displace virtual electrode lead is dropped, thereby displaying the virtual electrode leads in a new lead configuration.

Abstract: Exemplary external medical devices are configurable to communicate with an implantable medical device (IMD). One medical device includes multiple IMD telemetry ports operable to connect IMD telemetry mechanisms to the medical device. The medical device also includes a control unit configured to control the IMD telemetry mechanisms.

Abstract: This disclosure describes techniques that support delivering electrical stimulation current via at least two user-selected electrodes of an implantable medical device (IMD) and automatically delivering balancing current below via at least one non-selected electrode. Balancing currents delivered via the at least one non-selected electrode may be configured with an amplitude below a perception threshold of a patient. Delivery of balancing current via the at least one third electrode may allow an implantable medical device to automatically balance the total current delivered to a patient.

Abstract: A programming system allows a user to program therapy parameter values for therapy delivered by a medical device by specifying a desired therapeutic outcome. In an example, the programming system presents a model of a brain network associated with a patient condition to the user. The model may be a graphical representation of a network of anatomical structures of the brain associated with the patient condition and may indicate the functional relationship between the anatomical structures. Using the model, the user may define a desired therapeutic outcome associated with the condition, and adjust excitatory and/or inhibitory effects of the stimulation on the anatomical structures. The system may determine therapy parameter values for therapy delivered to the patient based on the user input.

Abstract: Techniques are described for generating electrical stimulation current pulses for delivery of electrical stimulation therapy via a current-controlled system that emulates voltage pulses generated via a voltage-controlled system.

Abstract: Systems and methods are provided for graphically configuring leads for a medical device. According to one aspect, the system generally comprises a medical device and a processing device, such as a programmer or computer, adapted to be in communication with the medical device. The medical device has at least one lead with at least one electrode in a configuration that can be changed using the processing device. The processing device provides a graphical display of the configuration, including a representative image of a proposed electrical signal to be applied by the medical device between the at least one electrode of the medical device and at least one other electrode before the medical device applies the electrical signal between the at least one electrode and the at least one other electrode. In one embodiment, the graphical display graphically represents the lead(s), the electrode(s), a pulse polarity, and a vector.

Abstract: Systems, devices and methods for triaging health-related data, such as significant health-related events associated with health-related parameters, are disclosed. One aspect is a method for use in managing a patient's health within a patient management system. In various embodiments of the method, a number of predetermined events are accessed. The events are related to the patient's health and are identified by the patient management system. Each of the predetermined events are classified according to severity using a color-code system. In various embodiments, a red event is an imminent life threatening event, a yellow event is a serious health-related condition that is not imminently life threatening, and a green event is an event that is neither an imminent life threatening event nor a serious health-related condition. Other aspects and embodiments are provided herein.

Abstract: Neurostimulation assemblies, systems, kits, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles or nerves inside the body and stimulus generators or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and a removable electronics pod, the electronics pod including stimulation generation circuitry, a power input bay to hold a disposable power source, and user interface components. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body.

Abstract: A control unit for an implantable medical device includes a housing and electronics within the housing. The electronics control an RF emission from the control unit. An antenna is pivotably connected to the housing. The antenna is movable between a stowed position where RF emission from the antenna is prevented and a deployed position where RF emission from the antenna is permitted. To use the external control unit to effect communication between an external control unit and an implanted medical device, the user places the external control unit within electronic communication range of the implanted medical device. The control unit antenna is moved from the stowed position to a deployed position where RF emission from the antenna is permitted. RF waves are emitted from the antenna to establish communication between the external control unit and the implanted medical device.

Abstract: A module for measuring physical attributes linked to includes a pad that is attachable or wearable to the body of a person; a signal sensing unit installed on the pad to sense at least one type of physical attributes signal that changes according to motions of the body; and a transmitting unit transmitting the physical attributes signal sensed by the signal sensing unit. A system including the module and a method of applying the module is also provided.

Abstract: A system and method for rapidly switching stimulation parameters of a Spinal Cord Stimulation (SCS) system increases the number of stimulation parameter sets that may be tested during a fitting procedure, or alternatively, reduces the time required for the fitting procedure. The switching method comprises selecting a new stimulation parameter set, and setting the initial stimulation levels to levels at or just below an estimated perception threshold of the patient. The estimated perception level is based on previous stimulation results. The stimulation level is then increased to determine a minimum stimulation level for effective stimulation, and/or an optimal stimulation level, and/or a maximum stimulation level, based on patient perception.

Abstract: Systems and methods for adjusting a therapy delivered to a patient include detecting a value of at least one sensed patient parameter and adjusting a therapy parameter value to accommodate different patient parameter values. A data structure including a plurality of patient parameter values and associated therapy parameter values may be stored within a medical device or a programming device. Upon detecting a patient parameter value, an associated therapy parameter value from the data structure may be selected. If no therapy parameter value is associated with the detected patient parameter value, an intermediate therapy parameter value may be generated by interpolating between the most recently implemented therapy parameter value and a stored therapy parameter value. In some embodiments, the rate of shifting between parameters of two stored or interpolated therapy parameter values may be based on the rate of change of the patient parameter value over time.

Abstract: Some embodiments of an infusion pump system can include a controller device that communicates with a pump device, the pump device having a memory device. The controller device can be configured to record controller-related data, such as user profile data on the memory device of the pump device. This user profile data that is stored in the memory of the pump device can serves as a data backup system that permits the user to program a new controller device in a situation where the original controller device is lost or damaged. In addition or in the alternative, the controller device can be configured to receive controller-related data, such as software update programs or backup controller data, from the memory device of the pump device.

Abstract: An improved implantable pulse generator (IPG) containing graceful shutdown circuitry is disclosed. A magnet sensor senses the presence of an emergency shutdown magnet. Output of the magnet sensor is conditioned by a signal conditioning circuit. Output of the signal conditioning circuit is delayed by a delay element before being fed to a power cut-off switch, which cuts-off power to the IPG circuitry. An interrupt signal is routed from before the delay element to the IPG processor as an indicator of imminent shutdown. The processor launches shutdown routine that carries out shutdown operations such as logging the emergency shutdown event, saving and closing open files, saving data from volatile memory to non-volatile memory, etc., before the power cut-off switch is activated upon elapsing of delay provided by the delay element. The magnet sensor, signal conditioning circuit, and delay element are powered separately from the rest of the circuitry of the IPG.

Abstract: This disclosure describes techniques for delivering electrical stimulation at one or more phases relative to an ongoing oscillating signal in a patient, and then mapping the response to the oscillating signal. The techniques may reduce or eliminate the oscillating signal. In one example, the disclosure is directed to a method that includes delivering a set of first electrical stimulation at a plurality of phases relative to an oscillating signal, measuring a response in the oscillating signal to the set of first electrical stimulation after delivering electrical stimulation at each respective phase of the plurality of phases, determining a phase at which to deliver second electrical stimulation based on the measured responses, and delivering the second electrical stimulation to the patient at the determined phase to produce a therapeutic effect.

Abstract: Implantable electrical stimulation leads, method, and system are provided. Components of the system include a hermetically sealed integrated circuit controller, two or more hermetically sealed individually addressable satellite electrode structures and an inductive power source. The lead includes a housing, a conductor positioned within the housing, addressable stimulation units secured within the housing, wherein each stimulation unit includes a hermetically sealed integrated circuit, and a plurality of electrodes each electrically isolated from the other.

Abstract: An implantable medical device (IMD) comprising a controller adapted to execute instructions included in firmware, a programmable neural therapy source adapted to provide programmable electrical neural stimulation therapy to at least one neural stimulation electrode, and a state machine included in hardware circuitry coupled to the programmable neural therapy source. When neural therapy is initiated by a firmware instruction, the state machine is configured to automatically apply power to the neural therapy source when neural therapy is initiated by a firmware instruction and automatically remove power from the neural therapy source when neural therapy is terminated by a firmware instruction.