Abstract: An apparatus and method for enabling far-field radio-frequency communications with an implantable medical device in which an antenna is embedded within a dielectric compartment of the device. A helical antenna may be employed to save space while still permitting far-field telemetry over a desired range of frequencies.

Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures with electrical blocking stimuli are disclosed. In an aspect, neural activity is blocked cyclically with an electrical blocking stimulus source implanted adjacent a nerve. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.

Abstract: Various embodiments of a minimally invasive implantable medical device (IMD) system are described. In one embodiment, the implantable medical device system includes an external device for transmitting a communication signal and an implantable device for receiving the communication signal by inductive coupling. The implantable device is configured to harvest power from the inductively coupled communication signal and power a signal generator from the harvested power to generate a therapeutic electrical stimulation signal.

Abstract: An implantable medical device (IMD) has a housing enclosing an electronic circuit. The housing includes a first housing portion, a second housing portion and a joint coupling the first housing portion to the second housing portion. A polymer enclosure member surrounds the joint and circumscribes the housing in various embodiments. Other embodiments of an IMD housing are disclosed.

Abstract: An external medical device generates a drive signal inductively coupled to an implantable coil from an external coil. A regulator module coupled to the implantable coil generates an output signal in response to the inductively coupled signal and a feedback signal correlated to an amplitude of the inductively coupled signal. A signal generator receives the output signal for generating a therapeutic electrical stimulation signal. The control module adjusts the drive signal in response to the feedback signal to control the electrical stimulation signal.

Abstract: An exemplary method includes a sound processing unit 1) directing an implantable cochlear stimulator to apply a plurality of stimulation pulses each having a first pulse width by way of a plurality of electrodes during a first stimulation frame, the plurality of electrodes including a first electrode and a set of remaining electrodes, 2) detecting a change in impedance of the first electrode, 3) adjusting, in response to the change in impedance of the first electrode, a pulse width parameter associated with the first electrode to define a second pulse width, and 4) directing the implantable cochlear stimulator to apply a stimulation pulse having the second pulse width by way of the first electrode and a plurality of stimulation pulses having the first pulse width by way of the set of remaining electrodes during a second stimulation frame subsequent to the first stimulation frame.

Abstract: Techniques associated with a universal recharging device for recharging a power source of implantable medical devices (IMDs). The recharging device includes an interface to allow an antenna assembly to be removably coupled. The antenna assembly has a primary coil and a corresponding sense coil. The sense coil has a configuration that is selected based on the configuration of the primary coil. The sense coil is adapted to prevent voltage across the primary coil from exceeding a maximum voltage amplitude allowable with the recharging device. The maximum voltage amplitude may be selected based on a maximum magnetic field strength to which a patient is to be exposed. In one embodiment, the maximum voltage amplitude is programmable.

Abstract: This disclosure describes techniques for obtaining an image of an anatomical implant region where leads associated with an implantable medical device are implanted in a patient, manipulating the image to show lead locations and placements, performing necessary image compression and manipulations, adjusting the image to associate it with information (e.g., patient, metadata, annotations, etc.) useful to a subsequent programmer retrieving the image, and transferring a copy of the captured image to the implantable medical device. The image stored in the implantable medical device may be retrieved at a later time by a user of programmer, where the user can use the image and other associated information to program subsequent therapy.

Abstract: An implantable medical device comprises a hermetically sealed housing having a housing wall with an interior surface, and an ultrasonic acoustic transducer, the transducer comprising one or more piezoelectric discs fixed to the interior surface of the housing wall, such that the housing wall acts as a diaphragm in response to induced movement by the one or more piezoelectric material discs.

Abstract: A method of transferring medical information can include transmitting medical information from a mobile personal medical device responsive to determining that a remote system is authorized to receive the medical information. Related Systems, devices, and computer program products are also disclosed.

Abstract: A data collection system collects and stores physiological data from an ambulatory patient at a high resolution and/or a high data rate (“more detailed data”) and sends a low-resolution and/or downsampled version of the data (“less detailed data”) to a remote server via a wireless network. The server automatically analyzes the less detailed data to detect an anomaly, such as an arrhythmia. A two-tiered analysis scheme is used, where the first tier is more sensitive and less specific than the second tier. If the more sensitive analysis detects or suspects the anomaly, the server signals the data collector to send more detailed data that corresponds to a time period associated with the anomaly. The more specific second tier analyses the more detailed data to verify the anomaly. The server may also store the received data and make it available to a user, such as via a graphical or tabular display.

Abstract: A system and related method for identifying a trigger event to a patient health-related exacerbation. The system includes at least one sensor configured to collect data related to the patient health-related exacerbation, an analyzer configured to validate the collected data, a patient interface device configured to receive patient inputs to at least one question, and an identifier device configured to receive the patient inputs and collected data and identify the trigger event. The system may also include an expert system configured to receive the patient inputs and the validated collected data and identify a primary patient disease, and a reporting device configured to generate reports related to the identified primary patient disease, patient inputs, and sensed patient conditions.

Abstract: An ambulatory monitoring device includes a sensor to monitor a physiological signal and a battery power source. The device also includes a wireless transceiver adapted to monitor a first frequency band having frequencies below 1 MHz and configured to detect and receive, using less than 10 micro-amps of current from the battery power source when operating, wireless communications within the first frequency band from a remote device at least one meter away. The wireless transceiver is further adapted to transmit—after receipt from the remote device of a first wireless communication within the first frequency band that includes an invitation for further communication—a second wireless communication in a second frequency band having frequencies above 10 MHz, the second wireless communication comprising data indicative of the physiological signal as sensed by the sensor.

Abstract: A wireless electrostimulation system can comprise a wireless energy transmission source, and an implantable cardiovascular wireless electrostimulation node. A receiver circuit comprising an inductive antenna can be configured to capture magnetic energy to generate a tissue electrostimulation. A tissue electrostimulation circuit, coupled to the receiver circuit, can be configured to deliver energy captured by the receiver circuit as a tissue electrostimulation waveform. Delivery of tissue electrostimulation can be initiated by a therapy control unit.

Abstract: A system and method for handling data received from an implantable medical device (IMD) is provided. The method includes communicating a device parameter value of an IMD device parameter from the IMD to an external device and determining, at the external device, that the communicated device parameter value is at an improper value. Additionally, in response to the determining that the communicated device parameter value is at an improper value, automatically performing at least one of re-programming the IMD device parameter with a selected substitute device parameter value, ignoring, or purging non-programmable data.

Abstract: Apparatuses for treatment of hyperhidrosis, Raynaud's phenomenon, cerebral ischemia and asthma and hypertension by nerve stimulation are disclosed. In particular, the invention relates to the improvement of these conditions by stimulating at least one ganglion selected from the group consisting of T-1 through T-4 ganglia, cervical ganglia, renal nerve or combinations thereof with an implantable, wireless, battery-less and lead-less stimulator. Stimulations of the ganglion may be carried out with pulsed radiofrequency, thermal energy or optical irradiation.

Abstract: In an example, configuring an implantable medical device by determining port usage can include, receiving a port data object, determining a lead configuration, configuring access to a programmable parameter, and displaying a visual indication of the lead configuration. The port data object can be received from the implantable medical device and can include data associated with a port of the implantable medical device capable of connecting to a lead. The determining a lead configuration can be based on the port data object. The configuring access to a programmable parameter can be based on the lead configuration of the implantable medical device.

Abstract: A system for effecting context-cognizant medical reminders for a patient; the system including: (a) at least one sensor unit situated proximately with the patient; the at least one sensor unit sensing and indicating at least one aspect of a personal context of the patient; (b) at least one long-range communication unit configured for wireless communication with a remote patient care monitoring facility via a wireless communication network; and (c) at least one short-range communication unit communicatingly coupled with the at least one sensor unit and with the at least one long-range communication unit; the at least one short-range communication unit and the at least one long-range communication unit cooperating to convey information from the at least one sensor unit to the remote patient care monitoring facility regarding the personal context of the patient.

Abstract: Therapeutic system with implantable therapeutic unit (ITU) comprising control unit (CU), memory, telemetry unit connected (in)directly to CU for wireless bidirectional transmission of data to/from external device (ED) and detection unit for detecting physiological patient data or operational data. CU triggers outgoing data transmission (DT) from ITU to ED based on preselected internal events and establishes standby mode for reception on part of telemetry unit for receiving beginning (header) of incoming DT from ED to therapeutic unit exclusively within preselected response time window after DT from ITU to ED.

Abstract: An electrode stimulation delivery system is described having a unit and a network of wireless remote electrodes configured for implantation within a plurality of spaced apart locations in the tissue, e.g. myocardium, of a patient. The control unit is configured to be positioned at or subcutaneous to the patient's skin, and includes a processor, an antenna configured for delivering RF energy in proximity to the plurality of wireless remote electrodes, and programming executable on the processor for wirelessly communicating to the network of wireless remote electrodes via the delivered RF energy to individually control pacing of the plurality of wireless remote electrodes. Each of the plurality of wireless remote electrodes comprises a metamaterial-based biomimetic harvesting antenna comprising a Van Atta array zero-phase transmission lines to receive the RF energy to power activation of the plurality of wireless remote electrodes.

Abstract: The invention provides a receiver associated with a body, e.g., located inside or within close proximity to a body, configured to receive and decode a signal from an in vivo transmitter which located inside the body. Signal receivers of the invention provide for accurate signal decoding of a low-level signal, even in the presence of significant noise, using a small-scale chip, e.g., where the chip consumes very low power. Also provided are systems that include the receivers, as well as methods of using the same.

Abstract: An apparatus for providing transdermal wireless communication includes medical implant circuitry; a transceiver coupled to the medical implant circuitry; a first metal surface having an end portion and a base portion; a second metal surface parallel to the first metal surface and connected to the first metal surface by a conductor, the second metal surface being separated from the first metal surface by a dielectric layer; a first radiating element tuned to a first frequency and disposed within the dielectric layer between the first metal surface and second metal surface; and a feed structure in electrical communication with the transceiver and the first radiating strip. The first radiating element has a first reactive portion at a first end thereof, a second reactive portion at a second end thereof, and a first radiating strip extending between the first reactive portion and the second reactive portion.

Abstract: An implantable medical device is provided having circuitry to control operation of the implantable medical device and a receiver configured to receive communication signals on an allocated band of a plurality of communication channels separated in frequency by a channel spacing. The receiver includes an oscillator and a signal source configured to apply a quench signal to the oscillator. The quench signal has a frequency corresponding to the channel spacing. The receiver is enabled to receive on all of the plurality of communication channels simultaneously by applying the quench signal.

Abstract: A tibial nerve stimulation device including a percutaneous electrode for inserting adjacent a stimulation site of a patient and a neurostimulator unit attachable to a transcutaneous electrode configured to be applied to skin adjacent the stimulation site. The neurostimulator unit includes a pulse generator electrically coupled to the percutaneous needle electrode and transcutaneous electrode and a microcontroller in communication with the pulse generator for monitoring a number of available treatment credits and activating the pulse generator, each available treatment credit corresponding to a treatment session and the pulse generator operable to be activated for performing the treatment session when the number of available treatment credits is at least one. A computer system is operable to communicate with the microcontroller of the neurostimulator unit for receiving a treatment credit request and transmitting the number of treatment credits purchased to the microcontroller of the neurostimulator unit.

Abstract: A system and method for virtually detecting a medical condition, such as acute myocardial infarction (AMI), in a patient using holistic diagnostic procedures implemented in medical devices. Physiological parameters in a patient are monitored in an implantable medical device (IMD) to detect deviations from desired characteristics. When severe physiological parameter deviations exist indicating with a desired certainty that the patient is experiencing a medical condition (e.g., AMI), an alert is generated. If only minor deviations from the desired characteristics exist, additional holistic diagnostic procedures are performed virtually for diagnosing whether the patient is likely to be experiencing the medical condition, such as querying the patient through an external device regarding symptoms the patient is experiencing and analyzing the patient's responses to the questions to determine whether the patient is experiencing the medical condition.

Abstract: A system may include an active implantable medical device implantable in a body of a patient and a patient programmer for the AIMD. The patient programmer may be configured to obtain magnetic resonance imaging (MRI) compatibility information relating to compatibility of the AIMD with an MRI modality.

Abstract: A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.

Abstract: A system and method for modifying the parameters of an implantable medical device includes an implantable medical device that communicates with a remote control device that, in turn, communicates through the browser of a computer or any other device capable of using mark-up language protocol. The computer optionally communicates with other computers and/or devices through a network.

Abstract: A method and system for enabling secure communications between an implantable medical device (IMD) and an external device (ED) over a telemetry channel. A telemetry interlock may be implemented which limits any communications between the ED and the IMD over the telemetry channel, where the telemetry interlock is released when the ED transmits an enable command to the IMD via a short-range communications channel requiring physical proximity to the IMD. As either an alternative or addition to the telemetry interlock, a data communications session between the IMD and ED over the telemetry channel may be allowed to occur only after the IMD and ED have been cryptographically authenticated to one other.

Abstract: A system and method for managing locally-initiated medical device interrogation is presented. An interface is provided over which to retrieve patient data recorded and transiently staged by a medical device monitoring physiological measures of a patient. The patient data is periodically retrieved by interfacing to and interrogating the medical device per a pre-defined schedule through the interface. Further retrieval of the patient data is permitted independent of the pre-defined schedule. The system stores remotely-specifiable criteria specified by a caregiver and controls patient-initiated patient data retrieval in accordance with the criteria.

Abstract: A method for quantification of the desynchronization between the clocks of two medical devices communicating wirelessly, for example, by HBC signals. The devices are separately clocked by slow clocks (CLK1/32k, CLK2/32k) and include selectively activated fast clocks (CLK1/10M, CLK2/10M). The method comprises: a) on a predetermined transition (T1) of a slow clock, transmission by one device of a synchronization query signal (SYNC) to the other device, b) counting of the pulses of the activated fast clock to detect a predetermined transition (T3) of the first slow clock, then c) transmitting from the other device to the first device a response signal (D1) and d) upon reception of the response signal, computing a temporal shift (OFFSET) according to the result (D1, D2) of the counting of the pulses of the fast clock. Two fast clocks, one on each device, also can be used.

Abstract: An electronic medical person access to a medical professional (MP) who can monitor, diagnose and treat the person from a remote site. The apparatus includes a plurality of medical treatment devices coupled to an electronic adapter designed to communicate with (A) each treatment device and (B) a local, first transmitting/receiving device which, in turn, is adapted to electronically communicate with a remote, second transmitting/receiving device used by the MP. Signals representing physiologic information of the person via the adapter to the MP and, in response, the MP may transmit a control signal to one or more treatment devices. The treatment devices may communicate via the adapter.

Abstract: Systems and methods for programming and logging medical device and patient data are provided. The systems include a handheld device, which is capable of communicating with a medical device, and a base station, which provides connectivity for the handheld device to accomplish various functions such as recharging, programming, data back-up and data entry. The methods comprise the steps of detecting a medical device, obtaining and recording information from the medical device. Additionally, medical device parameters may be modified and the recorded information may be archived for future reference.

Abstract: An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.

Abstract: An implantable medical device (IMD) comprises a transmitting/receiving (T/R) device for transmitting medical data sensed from a patient to, and for receiving control signals from, a medical expert (a human medical professional and/or a computerized expert system) at a remote location; an electronic medical treatment device for treating the patient in response to control signals applied thereto; and a sensor circuit, having a sensor circuit output, for producing sensor circuit output signal(s) representing medical data sensed from the patient. The IMD also includes logic device which analyzes the sensor circuit output signal(s) to detect a medical abnormality and, upon detecting an abnormality, either sends a notification signal representing a medical state of said patient to the medical expert at the remote location or sends a local treatment device control signal to the medical treatment device, or does both.

Abstract: An exemplary system for communicating with an implantable stimulator includes a coil configured to transmit a signal modulated with either on-off keying (OOK) modulation or Frequency Shift Keying (FSK) modulation. The system further includes a first telemetry receiver in the implantable stimulator configured to receive the signal in accordance with the OOK modulation and a second telemetry receiver in the implantable stimulator configured to receive the signal in accordance with the FSK modulation.

Abstract: A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

Abstract: A non-implantable communication unit (100) conducts wireless communication with an implantable medical device, IMD, (200). The communication unit (100) comprises a request processor (120) for generating power down requests destined to the IMD (200) and triggering temporary power down of the IMD radio equipment (220). When the communication unit (100) receives a data packet from the IMD (200) or a connected programmer (300) it determines the size of the data packet. A timer processor (140) sets a timer (152, 154) to a value defined based on the determined size. A processor controller (160) selectively controls the operation of request processor (120) to generate or stop generating the power down requests based on a current value of the timer (152, 154). Power down of the IMD radio equipment (220) is thereby prevented if it is likely that the IMD (200) comprises data to transmit to the communication unit (100) as predicted based on data packet sizes.

Abstract: The present disclosure involves a charging system for charging an implanted medical system. The charging device includes a replenishable power supply. The charging device includes a coil assembly electrically coupled to the power supply. The coil assembly includes a primary coil and a plurality of sense coils positioned proximate to the primary coil. The charging device includes electrical circuitry operable to: measure an electrical parameter of the coil assembly; and determine a position of the coil assembly relative to a position of the implanted medical device based on the measured electrical parameter. The charging device includes a visual communications interface operable to: receive an input from the electrical circuitry; and visually display on a screen the position of the coil assembly relative to the position of the implanted medical device based on the input received from the electrical circuitry.

Abstract: A medical device is capable of utilizing a pervasive wireless communications network, such as a digital wireless telephone network, personal communication services network or pager network, to directly communicate with a host computer without the need for a repeater device. The device includes a sensor capable of measuring a body characteristic, such as temperature or electrical cardiac activity, and generates clinical data describing the measurement. The device also includes a wireless transmitter/receiver unit capable of establishing a communications link with a host computer over the long-range wireless network. The wireless transmitter/receiver unit is capable of delivering the measured clinical data to the host computer over the wireless network. The wireless transmitter/receiver unit can also periodically deliver status information regarding the operation of the implantable device to the host computer.

Abstract: A system embodiment comprises at least one respiration sensor, a neural stimulation therapy delivery module, and a controller. The respiration sensor is adapted for use in monitoring respiration of the patient. The neural stimulation therapy delivery module is adapted to generate a neural stimulation signal for use in stimulating the autonomic neural target of the patient for the chronic neural stimulation therapy. The controller is adapted to receive a respiration signal from the at least one respiration sensor indicative of the patient's respiration, and adapted to control the neural stimulation therapy delivery module using a respiratory variability measurement derived using the respiration signal.

Abstract: A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.

Abstract: A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured for electrical communication with a power source, and an antenna associated with the at least one processor. The at least one processor may be configured to communicate with an implant circuit located within the body of the subject, cause the implant circuit to receive power in a first power mode and in a second power mode, wherein a first level of power delivered in the first power mode is less than a second level of power delivered in the second power mode, and wherein during a therapy period, power delivery in the first mode occurs over a total time that is greater than about 50% of the therapy period.

Abstract: A programming device used to program delivery of therapy to a patient by a medical device, such as an implantable neurostimulator or pump, maintains or accesses a programming history for the patient. The programming history may take the form of a record of programs, e.g., combinations of therapy parameters, tested during one or more prior programming sessions. The programming device may analyze, or otherwise use the programming history to provide guidance information to a user, such as a clinician, which may assist the user in more quickly identifying one or more desirable programs during a current programming session.

Abstract: An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician.

Abstract: Example techniques for communicating between two medical devices are described. One medical device may be an implantable medical device. Another medical device may be a lead-borne implantable medical device. The lead-borne implantable medical device may be referred to as a satellite. The implantable medical device may measure impedance of a path including at least two electrodes, at least one of which is on the lead, using an impedance measurement module. In some example implementations of this disclosure, the implantable medical device may also use the impedance measurement module to communicate with the satellite on the lead.

Abstract: A blood pump includes an impeller having a plurality of foldable blades and a cannula having a proximal portion with a fixed diameter, and a distal portion with an expandable diameter. The impeller can reside in the expandable portion of the cannula. The cannula has a collapsed condition for percutaneous delivery to a desired location within the body, and an expanded condition in which the impeller can rotate to pump blood. A flexible drive shaft can extend through the cannula for rotationally driving the impeller within the patient's body.

Abstract: A system level scheme for networking of implantable devices, electronic patch devices/sensors coupled to the body, and wearable sensors/devices with cellular telephone/mobile devices, peripheral devices and remote servers is described.

Abstract: A method, system, graphical user interface, and apparatus are provided for performing a patient management function for treating depression using an implantable medical device. At least one patient parameter relating to an electrical signal provided by the implantable medical device for treating depression is acquired. At least one therapy parameter defining the electrical signal is correlated with at least one patient parameter. An indication relating to the correlation of the therapy parameter and the patient parameter is provided.

Abstract: An antenna assembly is configured for use with an external device that is configured to wirelessly communicate with an implantable medical device (IMD). The antenna assembly may include an antenna member pivotally secured to a structure through a feed post, and a fixed tail fixed to the structure. The antenna member may be pivotal between a first orientation in which the antenna member electrically connects to the fixed tail, and a second orientation in which the antenna member is disconnected from the fixed tail. The antenna member and the fixed tail cooperatively operate in a first antenna mode when the antenna member is in the first orientation. The antenna member is configured to operate in a second antenna mode when the antenna member is in the second orientation.