Abstract: An ambulatory medical device comprises: a sensing component to be disposed on a patient for detecting a physiological signal of the patient; and monitoring and self-test circuitry configured for detecting a triggering event and initiating one or more self-tests based on detection of the triggering event. The ambulatory medical device senses the physiological signal of the patient substantially continuously over an extended period of time.

Abstract: A basket-type EP catheter is described. The EP catheter comprises a catheter proximal end that is electrically connected to a controller by an electrical cable having a single voltage-out (Vout) conductor and a catheter distal end supporting a distal connector that is detachably connectable to a basket-shaped configuration of a plurality of splines. Each spline supports an array of electrodes. By sampling the voltage signal on each of the plurality of electrodes sequentially or consecutively, only one Vout conductor is needed to transmit the voltage sample to the controller. In comparison to conventional EP catheters, this greatly reduces the number of conductors extending along the catheter shaft. The use of a Vout conductor is implemented by connecting a polling circuit or a “one-shot” circuit and a signal pass-transistor or transmission gate to each electrode.

Abstract: A supportive clothing article for a wearable cardioverter defibrillator (WCD), including a belt, the belt including a first end with a first portion of a fastener and a second end with a second portion of the fastener, wherein the belt is structured to fasten around the torso of patient below the chest area of the patient, the belt including a first conductive mesh portion adjacent the first end of the belt or the second end of the belt, two straps, a back portion extending from the belt at an intermediary position on the belt to each of the two straps, the back portion including a conductive mesh, a first support receptacle attached to and extending from the belt and attachable to one of the two straps, and a second support receptacle attached to and extending from the belt and attachable to the other of the two straps.

Abstract: An external medical device is provided. The device can include monitoring circuitry configured to sense physiological information of a patient and a controller with one or more input components. The controller can be configured to: detect one or more patient events based, at least in part, on the physiological information; notify the patient of the detection of the one or more patient events; and receive a patient response to the notification. The patient response can include a response activity identifiable by the input component, which is configured to test a psychomotor ability of the patient, cognitive ability of the patient, strength, balance, stability, and flexibility of the patient, and/or to substantially confirm that a person performing the activity is the patient.

Abstract: A flow sensor system for ventilation treatment comprises a flow conduit configured to allow gas flow between a first region and a second region, the flow conduit defining a lumen for the gas flow; a flow restrictor disposed within the lumen of the flow conduit between the first region and the second region; a first absolute pressure sensor disposed adjacent to the first region of the flow conduit and configured to measure a pressure of the gas flow at the first region of the flow conduit; and a second absolute pressure sensor disposed adjacent to the second region of the flow conduit and configured to measure pressure of the gas flow at the second region of the flow conduit.

Abstract: In embodiments, a Wearable Cardioverter Defibrillator (WCD) system includes a support structure for the patient to wear, and components that the support structure maintains on the patient's body. The components include a defibrillator, associated electrodes, and so on. The defibrillator can operate in a WCD mode while the patient wears the support structure. The defibrillator can further operate in a different, AED mode, during which time the patient need not wear a portion of the support structure, or even the entire support structure. Sometimes the AED mode is a type of a fully automatic AED mode. Other times the AED mode is a type of a semi-automated AED mode, where an attendant is present to administer the shock; at such times, the patient may not even need to have electrodes attached. This way the patient is more comfortable for a longer time.

Abstract: A data file system includes one or more files about a patient wearing a wearable cardiac defibrillator (WCD) system that has been assigned to them. The one or more files contain at least one patient identifier of the patient, compliance data about a history of the patient's wearing the WCD system, and possibly other data. The data file system can be accessed through a communication network when the patient uses a communication device. When so accessed, some of the contents can be viewed on a screen of the device, for example in the form of a website. In embodiments, the health care provider and friends and family can view such data and even enter inputs, which may create a situation that motivates the patient to comply better.

Abstract: Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation.

Abstract: A system and a method are provided for using a mobile computing system comprising that has a communication connection configured to communicate with an electrocardiographic (ECG) apparatus to acquire ECG signals from the subject through a plurality of ECG leads. The system includes a processor configured to receive the ECG signals through the communications connection and process the ECG signals to estimate at least one of a respiratory rate of the subject, a tidal volume of the subject, or an ischemic index or repolarization alternans of the subject, from the ECG signals. The processor is further configured to generate an alert upon determining at least one of the ischemic index or repolarization alternans is above a threshold value or a change in respiratory rate or tidal volume indicative of an abnormal respiratory event. The system also includes a display configured to display the alert.

Abstract: A medical device and method conserve electrical power used in monitoring cardiac arrhythmias. The device includes a sensing circuit configured to sense a cardiac signal, a power source and a control circuit having a processor powered by the power source. The control circuit is configured to operate in a normal state by waking up the processor to analyze the cardiac electrical signal for determining a state of an arrhythmia. The control circuit switches from the normal state to a power saving state that includes waking up the processor at a lower rate than during the normal state.

Abstract: In embodiments a WCD system is worn and/or carried by an ambulatory patient. The WCD system analyzes an ECG signal of the patient, to determine whether or not the patient should be given an electric shock to restart their heart. If so, then the WCD system first gives a preliminary alarm to the patient, asking them to prove they are alive if they are. The WCD system further determines whether the ECG signal contains too much High Amplitude (H-A) noise, which can distort the analysis of the ECG signal. If too much H-A noise is detected for a long time, the WCD system may eventually alert the patient about their activity, so that the ECG noise may be abated. The WCD system may even pause the analysis of the ECG signal, so that there will be no preliminary alarms that could be false until the ECG noise is abated.

Abstract: An ambulatory medical device comprises: a sensing component to be disposed on a patient for detecting a physiological signal of the patient; and monitoring and self-test circuitry configured for detecting a triggering event and initiating one or more self-tests based on detection of the triggering event. The ambulatory medical device senses the physiological signal of the patient substantially continuously over an extended period of time.

Abstract: A wearable medical monitoring (WMM) system may be worn for a long time. Some embodiments of WMM systems are wearable cardioverter defibrillator (WCD) systems. In such systems, ECG electrodes sense an ECG signal of the patient, and store it over the long-term. The stored ECG signal can be analyzed for helping long-term heart rate monitoring of the patient. The heart rate monitoring can be assisted a) by special filtering techniques that remove short-term variations inherent in patients' short-term heart rate determinations, and b) by indication techniques that indicate when conditions hampered sensing of the ECG signal too much for a reliable heart rate determination.

Abstract: A patient-worn arrhythmia monitoring and treatment device includes a pair of therapy electrodes and at least one pair of sensing electrodes disposed proximate to the skin and configured to continually sense at least one ECG signal of the patient over an extended period of time. The device includes a therapy delivery circuit coupled to the pair of therapy electrodes and configured to deliver one or more therapeutic pulses. A controller coupled to therapy delivery circuit is configured to analyze the at least one ECG signal and detect one or more treatable arrhythmias and cause the therapy delivery circuit to deliver the one or more therapeutic pulses to the patient. At least one of the one or more therapeutic pulses is formed as a biphasic waveform delivering within 15 percent of 360 J of energy to a patient body having a transthoracic impedance from about 20 to about 200 ohms.

Abstract: A print system includes a print device and an information processor connected to the print device via a network. The information processor includes an information acquisition section that acquires, from a voice mediation device, information including a keyword included in a print instruction given by a user by voice, a guidance section that outputs, to the voice mediation device, a guidance message to be output by voice, a print data transmission section that generates print data using content based on the keyword acquired by the information acquisition section in response to an output of the guidance message and transmits the print data to the print device, and a proficiency determination section that determines proficiency indicating a level of proficiency of the user for the print instruction. Based on the proficiency, the guidance section generates the guidance message that is used for the acquisition of the keyword by the information acquisition section.

Abstract: The present application discloses a method for identifying arrhythmia, a device for identifying arrhythmia, and a computer readable medium. The method includes: acquiring a type of arrhythmia to be identified; acquiring an ECG signal collected by an ECG acquisition device; detecting feature wave information in the ECG signal according to the type of arrhythmia to be identified; extracting a feature parameter from the denoised ECG signal and the feature wave information according to the type of arrhythmia to be identified; and identifying, by a classifier, an occurrence of the type of arrhythmia to be identified according to the feature parameter.

Abstract: In some embodiments, a wearable cardioverter defibrillator (“WCD”) system comprises a support structure configured to be worn by a patient, a power source, an energy storage module configured to be coupled to the support structure, to be charged from the power source and to store an electrical charge, a discharge circuit coupled to the energy storage module, the discharge circuit controllable to discharge the electrical charge so as to cause a shock to be delivered to the patient, a measurement circuit configured to render a physiological input from a patient physiological signal, a user interface configured to output one or more human-perceptible indications, and a processor.

Abstract: Implementations of conductive energy weapons (CEWs) may include a shock generating circuit configured to couple to a power source, two electrodes operatively coupled to the shock generating circuit, and a safety circuit operatively coupled to the shock generating circuit. The shock generating circuit may be configured to generate a first pulse train and deliver the first pulse train to a target, and may be configured to generate at least a second pulse train and deliver the at least second pulse train to a target. The safety circuit may be configured to prevent the CEW from applying pulse trains to the target after a predetermined number of pulse trains. The first pulse train may include two or more pulses having waveforms substantially identical with each other, each of the waveforms of the two or more pulses having both a positive voltage segment and a negative voltage segment.

Abstract: In some examples, a processor is configured determine whether efficacy of therapy delivered by a medical device to the patient may have changed and generate a notification based on the determination. For example, a processor may be configured to determine whether a bioelectrical brain signal indicative of activity of a brain of a patient includes a biomarker that indicates efficacy of therapy delivered by a medical device to the patient may have changed, and generate notification based on determining the bioelectrical brain signal includes the biomarker. In some examples, the processor modifies the therapy delivered to the patient prior to generating the notification.

Abstract: In some examples, determining a heart failure status of a patient using a medical device comprising a plurality of electrodes includes determining an estimated arterial pressure waveform of the patient based on an arterial impedance signal received from at least two of the plurality of electrodes. The estimated arterial pressure waveform may comprise a plurality of arterial pressure cycles. Each of the plurality of arterial pressure cycles may correspond to a different cardiac cycle of a plurality of cardiac cycles of the patient. At least one value of an intrinsic frequency of the corresponding arterial pressure cycle may be determined for at least some of the plurality of cardiac cycles and the heart failure status of the patient may be determined based on the at least one value of the intrinsic frequency.

Abstract: A method for detection of interference in impedance based monitoring of a subject by using a monitor is disclosed. The method comprising, connecting the subject to the monitor using one or more leads; and before current is applied to the subject, measuring voltage on the subject via at least one of the one or more leads and if any voltage is detected then the monitor indicates a warning. An impedance based monitor is disclosed, the monitor being connectable to a subject. The monitor is configured to measure voltage on the subject, before any current is applied to the subject, and if any voltage is detected then the monitor is configured to indicate a warning.

Abstract: A system including an ambulatory medical treatment device is provided. The ambulatory medical treatment device includes a memory, a treatment component configured to treat a patient, at least one processor coupled to the memory and the treatment component, a user interface component, and a system interface component. The user interface component is configured to receive an update session request and to generate the update session identifier responsive to receiving the request. The system interface component is configured to receive an encoded request including an identifier of an update session and device update information, to decode the encoded request to generate a decoded request including the device update information and the identifier of the update session, to validate the decoded request by determining that the update session identifier matches the identifier of the update session, and to apply the device update information to the ambulatory medical treatment device.

Abstract: A defibrillation system for synchronized cardioversion of a patient includes a first housing that includes a measurement circuit configured to receive electrocardiogram (ECG) signals and measure ECG parameters based on the ECG signals, and a first processor configured to analyze the ECG parameters, and initiate communication of a synchronization signal for a second processor for delivery of one or more defibrillation pulses and further includes a second housing that is separate from and external to the first housing and that includes a shock delivery circuit, and the second processor which is configured to receive the communication of the synchronization signal from the first processor, and control the shock delivery circuit to deliver the one or more defibrillation pulses in response to the synchronization signal.

Abstract: In embodiments, a Wearable Cardioverter Defibrillator (WCD) system includes a support structure for the patient to wear, and components that the support structure maintains on the patient's body. The components include a defibrillator, associated electrodes, and so on. The defibrillator can operate in a WCD mode while the patient wears the support structure. The defibrillator can further operate in a different, AED mode, during which time the patient need not wear a portion of the support structure, or even the entire support structure. Sometimes the AED mode is a type of a fully automatic AED mode. Other times the AED mode is a type of a semi-automated AED mode, where an attendant is present to administer the shock; at such times, the patient may not even need to have electrodes attached. This way the patient is more comfortable for a longer time.

Abstract: Disclosed is a system that includes both an Airway and Ventilation device (AV) and an Automated External Defibrillator (AED) device. The system is provided with components for assisting only minimally trained persons to operate it in emergency situations involving respiratory failure and/or cardiac arrhythmias. The system includes one or both of a mask for applying non-invasive ventilation and a ventilation tube for applying invasive ventilation.

Abstract: A wearable medical monitoring (WMM) system may be worn for a long time. Some embodiments of WMM systems are wearable cardioverter defibrillator (WCD) systems. In such systems, ECG electrodes sense an ECG signal of the patient, and store it over the long-term. The stored ECG signal can be analyzed for helping long-term heart rate monitoring of the patient. The heart rate monitoring can be assisted a) by special filtering techniques that remove short-term variations inherent in patients' short-term heart rate determinations, and b) by indication techniques that indicate when conditions hampered sensing of the ECG signal too much for a reliable heart rate determination.

Abstract: The present disclosure provides systems and methods for classifying signals of interest in a cardiac rhythm management (CRM) device. A CRM device includes an intrinsic activation sensing circuit configured to pass signals falling within a first passband, a crosstalk sensing circuit configured to pass signals falling within a second passband, wherein the second passband contains higher frequencies than the first passband, and a computing device communicatively coupled to the intrinsic activation sensing circuit and the crosstalk sensing circuit, the computing device configured to classify a signal of interest as one of an intrinsic activation signal and a crosstalk signal based on whether the signal of interest is passed by the intrinsic activation sensing circuit and the crosstalk sensing circuit.

Abstract: A polarization stream architecture is described. A transmitter may implement a reverse polarization stream to shape a first source signal in a first signal space to a first target signal in a second signal space. The reverse polarization stream is implemented as a cascade of reverse polarization steps. Each reverse polarization step includes a shuffle function, a split function, a scaling function and an offset function. Machine-learning techniques may be used to implement the scaling function and the offset function. A receiver may implement a polarization stream to recover the source signal.

Abstract: An electric treatment device includes an impedance detector to measure bioelectrical impedance at a site of a body of a user by using electrodes in contact with the site, a voltage controller to perform treatment of the site by controlling a voltage applied to the electrodes, and a timer to set a target time from when treatment of the site is started by the voltage controller to when the voltage value of the applied voltage reaches the target voltage value, based on the measured bioelectrical impedance. The greater the measured bioelectrical impedance is, the shorter the timer sets the target time. The voltage controller increases the voltage value of the applied voltage to the target voltage value based on the set target time.

Abstract: A training aid stimulator for providing fast perceptive feedback is disclosed. The training aid stimulator includes a first skin electrode and a second skin electrode both for making electrical contact to the body of a user, a charging module, a discharge module connected to one or more of the skin electrodes for a feedback discharging, and a processor for controlling the charging of a capacitor equivalent to a predetermined first voltage level, wherein the processor further being connected to the discharge module for controlling a feedback discharge of the capacitor equivalent. The stimulator comprises a voltage measurement module for measuring the level of charge of the capacitor equivalent, and the processor is configured for keeping the stimulator ready to discharge by repeatedly measuring the level of charge and by providing a maintenance charging when the voltage over said capacitance equivalent is at or below a predetermined second voltage level.

Abstract: An ambulatory medical device comprises: a sensing component to be disposed on a patient for detecting a physiological signal of the patient; and monitoring and self-test circuitry configured for defecting a triggering event and initiating one or more self-tests based on detection of the triggering event. The ambulatory medical device senses the physiological signal of the patient substantially continuously over an extended period of time.

Abstract: Techniques are disclosed for modulating the generation of charge current by operational circuitry included in an implantable medical device (IMD) for delivery of an induction stimulation pulse waveform by the IMD. The modulation may include modulating a charging circuit of the operational circuitry to facilitate the regulation of the induction stimulation pulse waveform. The techniques include monitoring an electrical parameter of a charging path during the delivery of the induction stimulation pulse and modulating the charging circuit based on the monitored electrical parameter.

Abstract: A defibrillation device for administering an electrotherapy, such as a dual-sequential defibrillation (DSD) electrotherapy. The defibrillation device can include a defibrillation therapy module, a physiological parameter module and a control module. The defibrillation therapy module can output one or more energies and the physiological parameter module can receive one or more physiological parameters, including electrocardiogram (ECG) data. The control module can analyze the physiological parameters to determine an indication for the administration of an electrotherapy and can determine a DSD electrotherapy. The DSD electrotherapy can be based at least in part on the physiological parameters, the indication for the administration of an electrotherapy or a review of the ECG data.

Abstract: A defibrillator and method for using a defibrillator which adopts an ECG analysis algorithm that can detect a cardiac arrhythmia in the presence of noise artifact induced by cardio pulmonary resuscitation (CPR) compressions. The apparatus and method provides both of a continuous and scheduled mode of operation for interleaving periods of CPR with electrotherapy, in a manner that improves the effectiveness of the rescue, resulting in more CPR “hands-on” time, better treatment of refibriUation, and reduced transition times between CPR and electrotherapy.

Abstract: Methods for automatically determining whether a patient monitor alarm will sound from a true or false signal, in particular from ventricular tachycardia (VT) and suppressing false alarms without eliminating any true alarms are presented. A multiresolution wavelet is extracted from a raw ECG waveform. Features are then extracted from the wavelets that account for summary statistics, noise, areas under the curve and summary statistics of the KL-divergence of the power spectra density between every two ECG leads. A classifier can be then be trained and its performance measured.

Abstract: An extra-cardiovascular implantable cardioverter defibrillator (ICD) is configured to induce a tachyarrhythmia by charging a high voltage capacitor to a voltage amplitude and delivering a series of pulses to a patient's heart by discharging the capacitor via an extra-cardiovascular electrode vector. Delivering the series of pulses includes recharging the high-voltage capacitor during an inter-pulse interval between consecutive pulses of the series of pulses.

Abstract: An automated external defibrillator includes a first pad at least partially colored in a first color, a second pad at least partially colored in a second color, and a main unit to which the first pad and the second pad are connected. The main unit has a first guidance surface that indicates how to attach of the first pad and the second pad. The first guidance surface has a first marker in the first color at a position corresponding to an attachment position of the first pad and a second marker in the second color at a position corresponding to an attachment position of the second pad.

Abstract: A method and medical device for generating a template that includes sensing a cardiac signal from a plurality of electrodes, determining a plurality of beats in response to the sensed cardiac signal, determining whether to store a beat of the plurality of beats in a subgroup of a plurality of subgroups for storing beats, determining whether a number of beats stored in one of the plurality of subgroups exceeds a subgroup threshold, and generating a template in response to beats stored in the one of the plurality of subgroups that exceeds the subgroup threshold.

Abstract: The present disclosure provides systems and methods for classifying signals of interest in a cardiac rhythm management (CRM) device. A CRM device includes an intrinsic activation sensing circuit configured to pass signals falling within a first passband, a crosstalk sensing circuit configured to pass signals falling within a second passband, wherein the second passband contains higher frequencies than the first passband, and a computing device communicatively coupled to the intrinsic activation sensing circuit and the crosstalk sensing circuit, the computing device configured to classify a signal of interest as one of an intrinsic activation signal and a crosstalk signal based on whether the signal of interest is passed by the intrinsic activation sensing circuit and the crosstalk sensing circuit.

Abstract: An extra-cardiovascular implantable cardioverter defibrillator (ICD) is configured to induce a tachyarrhythmia by charging a high voltage capacitor to a voltage amplitude and delivering a series of pulses to a patient's heart by discharging the capacitor via an extra-cardiovascular electrode vector. Delivering the series of pulses includes recharging the high-voltage capacitor during an inter-pulse interval between consecutive pulses of the series of pulses.

Abstract: A wearable defibrillator system includes a support structure with one or more electrodes in an unbiased state. A monitoring device monitors, for the long term, a parameter of the person that is not the person's ECG; rather, the monitored parameter can be the person's motion, a physiological parameter, or both. When a value of the monitored parameter reaches a threshold, such as when the person is having an actionable episode, the electrode becomes mechanically biased against the person's body, for making good electrical contact. Then, if necessary, the person can be given electrical therapy, such as defibrillation. As such, the electrodes of the wearable defibrillator system can be worn loosely for the long term, without making good electrical contact. This can reduce the person's aversion to wearing the defibrillation system.

Abstract: According to various method embodiments, a person is indicated for a therapy to treat a cardiovascular disease, and the therapy is delivered to the person to treat the cardiovascular disease. Delivering the therapy includes delivering a vagal stimulation therapy (VST) to a vagus nerve of the person at a therapeutically-effective intensity for the cardiovascular disease that is below an upper boundary at which upper boundary the VST would lower an intrinsic heart rate during the VST.

Abstract: The device includes a cardiac therapy circuit with a first terminal, and a peripheral therapy circuit with a second terminal. These terminals can either receive a cardiac detection/stimulation lead or a peripheral detection/stimulation lead of an organ. The device is configured to recognize the leads and automatically configure the connection terminals according to the type of lead received by the terminal. This includes discrimination methods for identifying the terminal on which a cardiac signal is detected, and selectively activating the cardiac therapy circuit and the peripheral therapy circuit based on the detection of the cardiac signal on a lead.

Abstract: An implantable medical device includes a low-power circuit, a high-power circuit, and a dual-cell power source. The power source is coupled to a dual-transformer such that each cell is connected to only one of the transformers. Each transformer includes multiple windings and each of the windings is coupled to a capacitor, and the capacitors are all connected in a series configuration. The low power circuit is coupled to the power source and issues a control signal to control the delivery of charge from the power source to the plurality of capacitors through the first and second transformers.

Abstract: A diagnostic ECG system analyzes lead traces for evidence of ST elevation in the lead signals. The pattern of ST elevation in leads having predetermined vantage points to the electrical activity of the heart and, in some instances, the presence of ST depression in certain other leads, identifies a specific coronary artery or branch as the culprit coronary artery for an acute ischemic event. ECG measurements which are associated with the identity of specific arterial occlusion locations are calculated and used to form a classifier of the probability of occlusion at different locations. The location identified as having the highest probability is indicated to a user as the most likely occlusion location.

Abstract: A method and system of driving an LED load. A driver is configured to deliver a level of current indicated by a control signal to the LED load when a PWM signal is ON and stop delivering the level of current when the PWM signal is OFF. An output capacitance element is coupled across a differential output of the LED driver. A feedback path, having a store circuit, is configured to store an information indicative of a first voltage level across the output capacitance element as a stored feedback reference signal just after the PWM signal is turned OFF. The feedback path causes the voltage across the output capacitance element to be at the first voltage level just before the PWM signal is turned ON.

Abstract: In a subcutaneous implantable cardioverter/defibrillator, cardiac arrhythmias are detected to determine necessary therapeutic action. Cardiac signal information is sensed from far field electrodes implanted in a patient. The sensed cardiac signal information is then amplified and filtered. Parameters such as rate, QRS pulse width, cardiac QRS slew rate, amplitude and stability measures of these parameters from the filtered cardiac signal information are measured, processed and integrated to determine if the cardioverter/defibrillator needs to initiate therapeutic action.

Abstract: A out-of-hospital cardiac treatment apparatus, comprising: a cardiac waveform monitor capable of sensing a physiological signal from a heart of a patient and wirelessly transmitting the sensed physiological signal to a remote medical provider, an electrical stimulator adapted to deliver a therapeutic dose of electrical energy to the heart of the patient, a medical provider transceiver adapted to receive the sensed physiological signal from the cardiac waveform monitor and also wirelessly transmit a command signal to control the electrical stimulator.

Abstract: An electrical living body stimulation signal waveform generation device includes a waveform generation unit that generates a low-frequency pulse signal wave and a high-frequency signal wave individually, and a waveform synthesis circuit that superimposes the high-frequency signal wave on the low-frequency pulse signal wave during an ON period of the low-frequency pulse signal wave to form a synthesized wave having a waveform in which a level gradually rises from a point of time when the superimposition is started and the ON period and an OFF period are continuously repeated, wherein the synthesized wave is given as an electrical stimulus to a living body.

Abstract: A technology to grasp a state of a human being more accurately is provided. The technology is provided with means for acquiring a time-series waveform of a frequency from a time-series waveform of a biological signal sampled from the upper body of a human being and for further acquiring a time-series waveform of frequency slope and a time-series waveform of frequency fluctuation and for applying frequency analysis to them. In the frequency analysis, a power spectrum of each frequency corresponding to a functional adjustment signal, a fatigue reception signal, and an activity adjustment signal, respectively, determined in advance is acquired. Then, a state of a human being is determined from a time-series change of each power spectrum.