Pulse Signal Patents (Class 607/72)
  • Publication number: 20090132010
    Abstract: A system and method for generating an electrical signal for use in biomedical applications may have power efficient features, support battery powered operation and, support a reduced risk of shock hazard. The system may include a controller for generating one or more control signals operable to control pulse generating and waveform processing circuits. The control signals may include at least two states alternating in a chosen pattern as a function of time. During at least one of the control signal states, an oscillator for generating a pulsed signal may be operable. During at least another of the control signal states, the oscillator can be disabled and completely shut off in order to conserve considerable power. The generated pulses may be processed to provide desired intensity and frequency components. The processed signals may be applied to biological material.
    Type: Application
    Filed: November 19, 2007
    Publication date: May 21, 2009
    Inventor: James W. Kronberg
  • Publication number: 20090069864
    Abstract: Quantity and time for medical operation are measured after starting the medical operation (step S1). Parameters in a parameter protection mode and parameters in a standard mode are compared so as to determine whether or not contents in the parameters coincide and whether or not five minutes passes (step S2). If five minutes do not pass, it is detected whether or not a power supply switch is turned off (step S4). If it is not turned off, the operation returns to the step S1 so as to determine whether or not the power supply is turned off within five minutes in steps S3 and S4 while measuring the quantity and the time for the medical operation. If five minutes passes without turning off the power supply, data for the quantity and the time for the medical operation are loaded in a memory (step S5). After that, the operation is completed.
    Type: Application
    Filed: November 6, 2008
    Publication date: March 12, 2009
    Applicants: ITO CO., LTD., HIROSE ELECTRIC CO., LTD.
    Inventors: Toshimasa Sakagami, Hirotsugu Sato, Takashi Nemoto
  • Patent number: 7486993
    Abstract: The present invention provides for applying electric impulse trains to a patient. A ditherer generates a plurality of indicia, each of the plurality of indicia corresponding to an impulse train. The ditherer is further configured to vary the time period between generating the indicia corresponding to the plurality of impulse trains. There is also a plurality of outputs for each of the plurality of indicia. Each of the two impulse trains are substantially 180 degrees out of phase with one another.
    Type: Grant
    Filed: August 5, 2004
    Date of Patent: February 3, 2009
    Assignee: Neurotone Systems, Inc.
    Inventors: James Ray Gilmer, John G. Buie, John R. Buie, Jason Worchel
  • Patent number: 7480531
    Abstract: Techniques are provided for generating plateau-shaped cardioversion shocks having reduced lead edge voltages. The reduced leading edge voltages are provided primarily to reduce the likelihood that any cardiac pain receptors will fire twice during a single cardioversion shock. Other techniques described herein relate to the generation of plateau-shaped shocks without reduced leading edge voltages. Still other techniques pertain to the generation of pre-pulse pain inhibition (PPI) pulses, particularly PPI pulses having chevron-shaped waveforms.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: January 20, 2009
    Assignee: Pacesetter, Inc.
    Inventors: Mark W. Kroll, J. Christopher Moulder
  • Publication number: 20090018620
    Abstract: The present invention relates to a method for eliciting ejaculation in a male individual, comprising delivering one or more stimulation pulses to lumbar spinothalamic (LSt) cells.
    Type: Application
    Filed: October 9, 2007
    Publication date: January 15, 2009
    Applicant: PELVIPHARM
    Inventors: Jacques Bernabe, Aren Borgdorff, Francois Giuliano
  • Publication number: 20080228244
    Abstract: A system for producing maximal, but reversible bioeffects, for neuromuscular disruption. Methods for facilitation of neuromuscular functions in diseases and conditions of decreased excitability are provided.
    Type: Application
    Filed: March 17, 2008
    Publication date: September 18, 2008
    Applicant: Old Dominion University
    Inventors: Andrei Pakhomov, Karl Schoenbach, Juergen Kolb, Ravindra Joshi
  • Publication number: 20080208284
    Abstract: Methods for neuromodulation using waveform signals. In certain embodiments, an input waveform is obtained from a signal source site in a source subject and an output waveform is applied to a target site in a target subject. The source subject is a human or animal and the signal source site is in the nervous system, including the brain. The source subject and target subject are the same subjects or different subjects. The output waveform is identical to the input waveform or derived from the input waveform. In some embodiments, the output waveform is modified in response to physiologic feedback. Also provided are systems for neuromodulation using waveform signals.
    Type: Application
    Filed: November 20, 2007
    Publication date: August 28, 2008
    Applicants: THE CLEVELAND CLINIC FOUNDATION, INTELECT MEDICAL,INC.
    Inventors: Ali Rezai, Andre Machado, Keith Carlton
  • Publication number: 20080177339
    Abstract: A stimulation system for a nerve, including a cuff configured and arranged to be placed, at least partially, around the nerve, and a plurality of electrode contacts disposed on the cuff such that distances between a first electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the first electrode contact are different.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 24, 2008
    Applicant: CVRX, Inc.
    Inventors: Stephen L. Bolea, Robert S. Kival, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
  • Publication number: 20080161887
    Abstract: An electrode assembly having homogeneous noble metal or blended alloy nanostructures for enhancement of capacitive charge injection. Applications can include stimulation of the baroreflex, neural stimulation and cardiac stimulation. In one embodiment, a matrix of substantially elongate nanocylinders or nanotubes are configured to deliver electrical charge to a target tissue, conducting charge substantially along the elongate axes of the nanostructures. The configuration enhances the real or effective area of the electrode to promote capacitive charge injection, and entraps solution for more complete recovery of electro-generated species. Certain embodiments may be configured to apply a suction through the electrode for temporary placement of the electrode for mapping the response of the electrode vs. positioning.
    Type: Application
    Filed: December 28, 2006
    Publication date: July 3, 2008
    Applicant: CVRx, Inc.
    Inventor: Jeffrey J. Hagen
  • Publication number: 20080147142
    Abstract: Methods and systems for artificially stimulating user deglutition without substantial aspiration are provided. Methods and systems include artificially stimulating user deglutition according to various specialized programs, including passive user secretion maintenance programs, active feeding programs, proprioceptive feedback programs, and others.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: Roy L. Testerman, Jon P. Davis, Nathan Andrew Torgerson, Robyn Lee Jagler, James Britton Hissong, Christy Ludlow, Pamela Reed Kearney
  • Publication number: 20080147141
    Abstract: Artificially stimulated deglutition methods and systems including providing a portable system born by a user for controlling a component of a complete swallowing act without substantial aspiration. The system includes a controller, a signal generator, and a subcutaneously positioned electrode array with at least one electrode. The electrode array is subcutaneously positioned and is operated to stimulate a single deglutition muscle where the single deglutition muscle is the only deglutition muscle directly artificially stimulated via the electrode array during the complete swallowing act. Systems and methods of nerve stimulation and selective nerve stimulation are also provided to artificially stimulate deglutition.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: Roy L. Testerman, Jon P. Davis, Nathan Andrew Torgerson, Robyn Lee Jagler, James Britton Hissong
  • Patent number: 7383089
    Abstract: A pulse generating apparatus has two like output channels that apply generated pulse signals of selected characteristics to two electrodes attached to a strap, each electrode receiving a different signal. The strap is attached to the foot so that the electrodes are positioned to stimulate with an electrical signal the abductor hallucis muscle of the foot to correct an imbalance due to overpowering by the adductor hallucis muscle. The signal strengthens the abductor hallucis muscle so that eventually it regains strength sufficient to counter balance the imbalance effect of the stronger adductor hallucis muscle and alleviate the bunion condition. The electrical signal generator generates signals that are pulses that are adjustable in frequency, modulation, pulse width and amplitude with modified square waves.
    Type: Grant
    Filed: June 17, 2004
    Date of Patent: June 3, 2008
    Inventor: Bassem M. Demian
  • Patent number: 7333858
    Abstract: A method for stimulating nerve or tissue fibers and a prosthetic hearing device implanting same. The method comprises: generating a stimulation signal comprising a plurality of pulse bursts each comprising a plurality of pulses; and distributing said plurality of pulse bursts across one or more electrodes each operatively coupled to nerve or tissue fibers such that each of said plurality of pulse bursts delivers a charge to said nerve or tissue fibers to cause dispersed firing in said nerve or tissue fibers.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: February 19, 2008
    Assignee: Cochlear Limited
    Inventors: Matthijs Killian, Ernst von Wallenberg, Guido Smoorenburg
  • Patent number: 7333857
    Abstract: The method disclosed herein entails spinal cord stimulation via electrodes placed directly into the dorsal horn, dorsal column, spinothalamic tract, nucleus cuneatus, nucleus gracilis, spinal tract of V, or spinal nucleus of V (nucleus caudalis) depending on the source of pain. This “intramedullary” stimulation “jams” or otherwise prevents the pain signal from being transmitted. The method provides a means to stimulate the targeted area directly, creating a stable means of stimulating the desired area, and decreasing stimulation of other structures.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: February 19, 2008
    Assignee: Arcl, Inc.
    Inventor: James N. Campbell
  • Patent number: 7319902
    Abstract: A method and device are disclosed for using electrochemistry to rejuvenate skin and underlying tissue and to build and strengthen muscles by applying pulses of DC electrical charge, at a duration in the range of about 0.2 to about 1 millisecond and a variable frequency in the range of about 400 to about 1200 Hertz, to the skin immersed into an container of an electrolyte by means of an anode immersed in or connected to the container to cause the muscle to twitch or only slightly contract with each pulse. The DC is applied at variable current amplitude of from about 1 to about 50 milliamperes, and a voltage in the range of about 50 to about 120 volts.
    Type: Grant
    Filed: May 9, 2005
    Date of Patent: January 15, 2008
    Inventor: Gregory O'Kelly
  • Publication number: 20070293918
    Abstract: A device (10, 50, 60, 70, 80, 90) is used to apply an electric pulse or spike to a patient to treat the patient. The device can have a series of preset treatments programmed therein. A user can select a treatment from menus displayed on a display (100). The impedance of the skin and underlying tissue to be treated can be measured prior to the treatment to locate active areas on the skin for treatment. The impedance measurement can be made at a sufficiently low level to avoid treatment of the patient that could cause a change in the impedance. A phase detector can be used to isolate the capacitance value in the impedance. The charge delivered to the patient can be measured and the device can adjust the charge as the skin impedance varies during treatment to deliver uniform charges to the skin. A variety of probes can be used with the device, with the device automatically detecting the type of probe attached.
    Type: Application
    Filed: September 19, 2006
    Publication date: December 20, 2007
    Inventors: Thomas C. Thompson, Martyn S. Abbott, Gary L. Byars, Garnet E. Dupuis, Vladimir P. Tepin
  • Publication number: 20070293917
    Abstract: A device (10, 50, 60, 70, 80, 90) is used to apply an electric pulse or spike to a patient to treat the patient. The device can have a series of preset treatments programmed therein. A user can select a treatment from menus displayed on a display (100). The impedance of the skin and underlying tissue to be treated can be measured prior to the treatment to locate active areas on the skin for treatment. The impedance measurement can be made at a sufficiently low level to avoid treatment of the patient that could cause a change in the impedance. A phase detector can be used to isolate the capacitance value in the impedance. The charge delivered to the patient can be measured and the device can adjust the charge as the skin impedance varies during treatment to deliver uniform charges to the skin. A variety of probes can be used with the device, with the device automatically detecting the type of probe attached.
    Type: Application
    Filed: June 15, 2006
    Publication date: December 20, 2007
    Inventors: Thomas C. Thompson, Martyn S. Abbott, Gary L. Byars, Garnet E. Dupuis, Vladimir P. Tepin
  • Patent number: 7299091
    Abstract: A method of treating patients for compulsive overeating includes stimulating left and right branches of the patient's vagus nerve simultaneously with electrical pulses in a predetermined sequence of a first period in which pulses are applied continuously, alternating with a second period in which no pulses are applied. The electrical pulses are preferably applied to the vagus nerve at a supradiaphragmatic location.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: November 20, 2007
    Assignee: Cyberonics, Inc.
    Inventors: Burke Barrett, Ramish K. Reddy, Mitchell S. Roslin
  • Patent number: 7295880
    Abstract: System and method for end of battery life operation of an implantable bilateral brain stimulator. The present system and method automatically measures one or more levels of electrical parameters in a battery system of the implantable stimulator. The measurement can be compared to threshold values. The implantable bilateral brain stimulator can then make automatic adjustments to the therapy when the levels of the electrical parameters in the battery system reach the threshold values. Adjustments to the therapy are made such that the patient is provided with an adjusted, but sufficiently safe, amount of therapy so as to extend the life of the battery and also to allow some physical symptoms alleviated by the system to return, thereby signaling the patient that medical attention needs to be sought.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: November 13, 2007
    Assignee: Medtronic, Inc.
    Inventor: Frans L. H. Gielen
  • Patent number: 7292890
    Abstract: Methods of stimulating a vagus nerve include providing at least one implantable stimulator with at least two electrodes, configuring the electrodes to apply stimulation that unidirectionally propagates action potentials along a vagus nerve, and applying the stimulation to the vagus nerve to effectively select afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation. At least one of the electrodes comprises a leadsless electrode.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: November 6, 2007
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K Whitehurst, James P McGivern, Rafael Carbunaru, Matthew I Haller, Tom Xiaohai He, Kerry Bradley
  • Patent number: 7280873
    Abstract: A method for treating an oropharyngeal disorder in a patient by neuromuscular electrical stimulation includes selectively placing a plurality of electrodes in electrical contact with tissue of a pharyngeal region of the patient. The method also includes the steps of providing a pulse generator for generating a series of electrical pulses, each of which comprises a biphasic symmetrical waveform with an interval between the two phases, and attaching the plurality of electrodes to the pulse generator so that the series of electrical pulses may be provided to the patient through the plurality of electrodes. According to the method, a series of electrical pulses, each of which comprises a biphasic symmetrical waveform with an interval between the two phases, is generated, and said series of electrical pulses is provided to the patient through the plurality of electrodes.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: October 9, 2007
    Assignee: ESD, LLC
    Inventors: Marcy L. Freed, Leonard A. Freed, Michael O. Christian, Howard Tucker, Bernard Kotton, Erol M. Beytas, Marie Asmar, Ed Dunlay, Tim Kretschmer
  • Patent number: 7254447
    Abstract: A method and apparatus include a therapeutic or developmental apparel that includes hardware and/or software for stimulating a muscle. Such apparel may comprise, for instance, of: a glove, a uniform, a shoe, a sock, a vest, a sleeve, a shirt, a hat, a helmet, a brace, a suspender, eye wear, a pad, jewelry, a watch and pants. A muscle of a user may be stimulated by the garment as the user moves, such as a when a golfer practices her swing. Combining such muscle stimulation with the act of practicing the movement of the swing has a synergistic effect of training the muscle as it builds strength. Similarly, a partial paralytic may regain strength in their hand by wearing a vest or other garment configured to transcutaneously deliver a stimulating signal. Where desired, the garment may include at least one electrode configured to deliver a stimulating signal to the wearer. In another or the same embodiment, wired electrodes may extend from the garment or an adjacent signal generator to the wearer.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: August 7, 2007
    Assignee: Therapeutic Innovations, Inc.
    Inventors: James M. Campos, Bruce D. Rowe
  • Patent number: 7191014
    Abstract: A living body stimulating apparatus capable of giving extensive therapeutic effects and softer feeling of stimulation. Rectangular wave pulse groups S containing a plurality of pulse density modulated higher frequency components or on-pulses than a rectangular wave pulse are applied repeatedly from conductor elements 24 to a human body. As a human body has a capacitive impedance, softer stimulation can be applied to the human body as compared with a rectangular wave having the same current and frequency. Furthermore, a pause period between on-pulses is varied by a stimulus generator means 8, so that a charging current to an equivalent electrostatic capacity of a human body is supplied little by little so as to slowly increase a charged quantity. As a result, cenesthesia of softer stimulation can be obtained.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: March 13, 2007
    Assignee: Techno Link Co., Ltd.
    Inventors: Tatsuyuki Kobayashi, Takashi Izumi
  • Patent number: 7167754
    Abstract: An alterphasic inverting stimulation strategy for use with a multichannel cochlear implant system consumes less power than similar strategies, yet provides better sound quality. The alterphasic inverting strategy is a strategy wherein stimulation pulses are strictly sequential, and wherein the timing and polarity of the channels is chosen such that positive and negative pulses are alternating in time in accordance with a defined pattern that staggers application of the pulses spatially across all the channels and inverts the polarity of pulses that are near each other either spatially or in time.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: January 23, 2007
    Assignee: Advanced Bionics Corporation
    Inventors: Stefaan Peeters, Filiep Vanpoucke
  • Patent number: 7133723
    Abstract: The cell enhancing device for an electrical pulse cosmetic meter, wherein the composite pulse generating device comprising an electrical pulse generating device, generating an electrical pulse sequence of a predetermined electrical pulse amplitude, wherein a frequency of said electrical pulse sequence is adjustable, a waveform adjuster, converting said electrical pulse sequence to a composite pulse sequence, and outputting said composite pulse sequence to a cosmetic head of said electrical pulse cosmetic meter. The present invention has the advantages of being small in size and light in weight. Furthermore, it greatly enhances circulation in skin structure of body, so as to achieve effective cosmetic results.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: November 7, 2006
    Assignee: Misty Li-Ming Chang
    Inventor: Eukki Qi Yu
  • Patent number: 7089061
    Abstract: A nausea control device which provides electrical stimulation to the K9 acupressure point or points on the finger of a patient. Various mounting structures may be used to hold the electrodes in place over the K9 point, and hold the pulse generation circuitry and power supply in convenient location relative to the electrodes and the patient.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: August 8, 2006
    Assignee: Abbott Laboratories
    Inventor: Thomas L. Grey
  • Patent number: 7039468
    Abstract: A simple, non-invasive method and apparatus for treating oropharyngeal disorders provides electrical stimulation to the oropharyngeal region of a patient. The apparatus includes an electrical neuromuscular stimulator that includes a pulse generator for generating a series of electrical pulses and a processor coupled to the pulse generator for controlling its operation. The apparatus also includes a first electrode and a second electrode, each of which includes a snap eyelet having a connector to which a lead wire may be attached, a conductive film and an adhesive and conductive gel layer that is adapted to be attached to the skin of the patient. The apparatus also includes at least one lead wire for attachment of the electrodes to the pulse generator and at least one adhesively backed tape overlay for securing the first and second electrodes to the skin of the patient.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: May 2, 2006
    Assignee: ESD Limited Liability Company
    Inventors: Marcy L. Freed, Leonard A. Freed, Michael O. Christian, Howard Tucker, Bernard Kotton, Erol M. Beytas, Ed Dunlay, Tim Kretschmer, Marie Asmar
  • Patent number: 7035691
    Abstract: A method and apparatus generate resonant sequences having pulses optimally spaced and configured to realize uniform contractions in a musculature. Namely, each subsequent pulse maintains tension within sarcomeres of the musculature as the resonant sequence propagates inwardly to progressively stimulate the entirety of the musculature. Variation in the width, spacing, polarity and/or amplitude of the pulses comprising the resonant sequence further overcomes accommodation and nutritional depletion while minimizing discomfort.
    Type: Grant
    Filed: January 15, 2002
    Date of Patent: April 25, 2006
    Assignee: Therapeutic Innovations, Inc.
    Inventor: James M. Campos
  • Patent number: 7031750
    Abstract: The present invention relates generally to an apparatus for managing the body fat of a human body and, more particularly, to a mobile communication terminal in which a body fat managing function is embedded, and an apparatus in which a body fat managing device is connected to a mobile communication terminal. The mobile communication terminal, in which a body fat managing function is embedded, includes a signal amplifying and converting unit for converting the measured value of body fat, a low frequency generating unit for generating low frequency waves, an input unit for receiving the body fat-related items, a display unit for displaying the measured value of the body fat, a memory unit for storing the measured value of the body fat, an adaptor unit connected to outside electrode lines, and a control unit for controlling the respective function units.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: April 18, 2006
    Assignee: HealthPia America, Co. Ltd
    Inventors: Min-Hwa Lee, Moon-Soo Kim
  • Patent number: 7013179
    Abstract: A percutaneous electrode array is disclosed for applying therapeutic electrical energy to a treatment site in the body of a patient. The array comprises a plurality of electrode microstructures which are inserted into the epidermis, thereby overcoming the inherent electrical impedance of the outer skin layers and obviating the need to prepare the skin surface prior to an electro-therapy treatment. The array preferably includes an adhesion layer to help keep the electrode microstructures inserted into the epidermis during the duration of the therapeutic treatment, and temperature and condition monitoring devices to ensure proper treatment and enhance patient safety.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: March 14, 2006
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 6944503
    Abstract: Pulsed electrical stimulation is applied to selected tissues via electrodes positioned on and/or in the body. Each electrode is connected to an output (108) of the apparatus. Each output (108) is connected between a high side switch (110) and a low side switch (112) of a switching array. Each stimulation pulse is subdivided into a number of time periods. By operation of the switches (110, 112) each electrode can be selected to operate as an anode or a cathode or neither during any given time period. The spatial and/or time summation of the anode-cathode currents is controlled to selectively to stimulate selected regions and/or types of tissues, typically nerve tissues.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: September 13, 2005
    Assignee: BMR Research and Development Limited
    Inventors: Louis Michael Crowe, Conor Michael Minogue
  • Patent number: 6944501
    Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: September 13, 2005
    Assignee: Neurospace, Inc.
    Inventor: Benjamin D. Pless
  • Patent number: 6941172
    Abstract: A device for, and method of restoring kidney function, the method including the steps of: (a) providing a device including: (i) a conducting coil, and (ii) a signal generator, operatively connected to a power supply, for providing a plurality of electrical impulses to the coil; (b) disposing the conducting coil proximate to a kidney of a patient, and (c) delivering the electrical impulses conducting to the conducting coil, so as to produce an electromagnetic field, the electromagnetic field acting so as to stimulate the kidney and at least partially restore kidney function.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: September 6, 2005
    Inventor: Zvi Nachum
  • Patent number: 6904322
    Abstract: Transcranial electrostimulation apparatus and method includes a first generator of bipolar pulses of a first predetermined frequency. A source of modulating control signals, producing an output at a second frequency less than the first predetermined frequency, is used to cause the output pulses from the first generator of pulses to vary in amplitude in a predetermined asymmetrical pattern at the frequency of the modulating control signals, with the asymmetrical pattern of signals applied to output electrodes designed to be attached to the scalp of a patient.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: June 7, 2005
    Assignee: Kalaco Scientific, Inc.
    Inventor: Yakov S. Katsnelson
  • Patent number: 6892099
    Abstract: An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: May 10, 2005
    Assignee: Minnesota Medical Physics, LLC
    Inventors: Ali Jaafar, Victor I. Chornenky
  • Patent number: 6889088
    Abstract: A pulse generating apparatus has two like output channels that apply generated pulse signals of selected characteristics to two electrodes attached to a strap, each electrode receiving a different signal. The strap is attached to the foot so that the electrodes are positioned to stimulate with an electrical signal the abductor hallucis muscle of the foot to correct an imbalance due to overpowering by the adductor hallucis muscle in the large toe. The signal strengthens the abductor hallucis muscle so that eventually it regains strength sufficient to counter balance the imbalance effect of the stronger adductor hallucis muscle and alleviate the bunion condition in the large toe. The electrical signal generator generates signals that are pulses that are adjustable in frequency, modulation, pulse width and amplitude with modified square waves.
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: May 3, 2005
    Inventor: Bassem M. Demian
  • Patent number: 6871099
    Abstract: An implantable stimulator(s), small enough to be located near or within an area of the spine responsible for sensations in a region experiencing chronic pain uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a power source/storage device is accomplished, for example, by inductive coupling with an external appliance. The small stimulator provides a means of stimulating a nerve(s) or other tissue when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power, it necessary. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one implant includes at least one sensor, and the sensed condition is used to adjust stimulation parameters.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: March 22, 2005
    Assignee: Advanced Bionics Corporation
    Inventors: Todd K. Whitehurst, James P. McGivern, Carla M. Mann, Janusz A. Kuzma
  • Patent number: 6871092
    Abstract: This invention relates to a new type of apparatus designed to modulate the neurovegetative system and integrate the neurovegetative action with that of the central nervous system. The method is not invasive, because it uses pulses transmitted through the skin; the intensity of the stimulus is controlled directly by the patient in order to achieve better integration with the central nervous system. This invention effectively treats vascular disorders resulting from obstruction of the arteries of the legs, heart and brain because it induces vasodilatation and increases blood flow and the production of new blood vessels. The method also improves lesions of the spinal column, especially those affecting the back and neck, and other orthopaedic disorders.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: March 22, 2005
    Inventor: Lorenzo Piccone
  • Patent number: 6862481
    Abstract: A pulse generating apparatus has two like output channels that apply generated pulse signals of selected characteristics to two electrodes attached to a strap, each electrode receiving a different signal. The strap is attached to the foot so that the electrodes are positioned to stimulate with an electrical signal the abductor hallucis muscle of the foot to correct an imbalance due to overpowering by the adductor hallucis muscle. The signal strengthens the abductor hallucis muscle so that eventually it regains strength sufficient to counter balance the imbalance effect of the stronger adductor hallucis muscle and alleviate the bunion condition. The electrical signal generator generates signals that are pulses that are adjustable in frequency, modulation, pulse width and amplitude with modified square waves.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: March 1, 2005
    Inventor: Bassem M. Demian
  • Patent number: 6853863
    Abstract: An apparatus for providing therapeutic electric current to a treatment site of a patient is disclosed, which provides two oscillating or pulsing electric alternating currents, of frequencies which differ from each other by as little as 1 Hz and up to about 250 Hz, but each being of frequency at least about 1 KHz. The apparatus requires only one feed electrode adapted to feed the electric currents to selected feed sites on or beneath the epidermal or mucous surface of the patient, and only one return electrode adapted to be positioned on or beneath the epidermal or mucous surface of the patient, locally to the treatment site. The apparatus includes a feedback subsystem to detect impedance changes in the patient and accordingly adjust the output of the apparatus.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: February 8, 2005
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Patent number: 6845270
    Abstract: A frequency transfer system for the destruction of pathogens using a recorded medium and a transfer unit is disclosed. The recorded medium contains at least one square wave at a frequency known to affect specific pathogens. Additional mathematically congruent square waves can also be recorded on the medium for simultaneous transmission. The transfer unit contains a coil and an amplifier. The coil absorbs the magnetic flux from the electromagnetic square waves and outputs scalar square waves. The amplifier increases the voltage and reverses the wave polarities to place the greatest scalar potentials at the positive node of said output square wave. The scalar waves are transferred to the user's body through output leads and electrodes.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: January 18, 2005
    Inventor: Joseph Debrouse
  • Publication number: 20040267333
    Abstract: An method and method for generating an electrical signal for use in biomedical applications, including two timing-interval generators, each optionally driving a multistep sequencer; analog, digital or hybrid means for combining the resulting timed signals into a complex electrical signal; optional filtering means for blocking direct current, removing selected frequency components from the resulting signal, and/or providing voltage step-up if needed; and conductive means for coupling the resulting signal to a human or animal body, food, beverage or other liquid, cell or tissue culture, or pharmaceutical material, in order to relieve pain, stimulate healing or growth, enhance the production of specific biochemicals, or devitalize selected types of organisms.
    Type: Application
    Filed: June 24, 2004
    Publication date: December 30, 2004
    Inventor: James W. Kronberg
  • Publication number: 20040243197
    Abstract: A pulse generating apparatus has two like output channels that apply generated pulse signals of selected characteristics to two electrodes attached to a strap, each electrode receiving a different signal. The strap is attached to the foot so that the electrodes are positioned to stimulate with an electrical signal the abductor hallucis muscle of the foot to correct an imbalance due to overpowering by the adductor hallucis muscle. The signal strengthens the abductor hallucis muscle so that eventually it regains strength sufficient to counter balance the imbalance effect of the stronger adductor hallucis muscle and alleviate the bunion condition. The electrical signal generator generates signals that are pulses that are adjustable in frequency, modulation, pulse width and amplitude with modified square waves.
    Type: Application
    Filed: June 17, 2004
    Publication date: December 2, 2004
    Inventor: Bassem M. Demian
  • Publication number: 20040236391
    Abstract: A living body stimulating apparatus capable of giving extensive therapeutic effects and softer feeling of stimulation. Rectangular wave pulse groups S containing a plurality of pulse density modulated higher frequency components or on-pulses than a rectangular wave pulse are applied repeatedly from conductor elements 24 to a human body. As a human body has a capacitive impedance, softer stimulation can be applied to the human body as compared with a rectangular wave having the same current and frequency. Furthermore, a pause period between on-pulses is varied by a stimulus generator means 8, so that a charging current to an equivalent electrostatic capacity of a human body is supplied little by little so as to slowly increase a charged quantity. As a result, cenesthesia of softer stimulation can be obtained.
    Type: Application
    Filed: July 22, 2003
    Publication date: November 25, 2004
    Applicant: Techno Link Co., Ltd.
    Inventors: Tatsuyuki Kobayashi, Takashi Izumi
  • Publication number: 20040230256
    Abstract: An electronic acupressure aide and stimulating device implemented using a hand-held or palm-held electronic computing device or another computing device which may be a designated unit. The electronic acupressure aide and stimulating device allows a practitioner to apply a pulse sequence to a set of predetermined acu-points such as those related to acupressure, acupuncture, trigger points or Jin-Shin Jyutsu, to name a few. A displayed chart related to the acu-points identifies the health condition and the pulse sequence.
    Type: Application
    Filed: May 15, 2003
    Publication date: November 18, 2004
    Inventor: Catherine Lin-Hendel
  • Publication number: 20040230253
    Abstract: Quantity and time for medical operation are measured after staring the medical operation (step S1). Parameters in a parameter protection mode and parameters in a standard mode are compared so as to determined whether or not contents in the parameters coincide and whether or not five minutes passes (step S2). If five minutes do not pass, it is detected whether or not a power supply switch is turned off (step S4). If it is not turned off, the operation returns to the step S1 so as to determine whether or not the power supply is turned off within five minutes in steps S3 and S4 while measuring the quantity and the time for the medical operation. If five minutes passes without turning off the power supply, data for the quantity and the time for the medical operation are loaded in a memory (step S5). After that, the operation is completed.
    Type: Application
    Filed: May 12, 2004
    Publication date: November 18, 2004
    Inventors: Toshimasa Sakagami, Hirotsugu Sato, Takashi Nemoto
  • Patent number: 6810286
    Abstract: Provided are novel stimulatory device for the controlled production of angiogenic growth factors. More specifically, a subthreshold pulse generator is used for the local production of vascular endothelial growth factor.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: October 26, 2004
    Assignee: Medtronic, Inc
    Inventors: Maura G. Donovan, Orhan Soykan, D. Curtis Deno, Lawrence J. Mulligan, Brian C. A. Fernandes
  • Patent number: 6795728
    Abstract: An apparatus and method for minimally invasive treatment of deep subcutaneous fat deposits in lieu of cosmetic surgery is disclosed. The apparatus comprises a high voltage pulse generator connected to two or more needle electrodes at least one of which is configured for placement deeply under the skin in a treatment site of the patient's body. High voltage pulses, delivered to the electrodes, create an electric field that kills subcutaneous fat cells.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: September 21, 2004
    Assignee: Minnesota Medical Physics, LLC
    Inventors: Victor I. Chornenky, Ali Jaafar
  • Patent number: 6792315
    Abstract: An apparatus for providing therapeutic electric current to a treatment site of a patient is disclosed, which provides two oscillating or pulsing electric alternating currents, of frequencies which differ from each other by as little as 1 Hz and up to about 250 Hz, but each being of frequency at least about 1 KHz. The apparatus requires only one feed electrode adapted to feed the electric currents to selected feed sites on or beneath the epidermal or mucous surface of the patient, and only one return electrode adapted to be positioned on or beneath the epidermal or mucous surface of the patient, locally to the treatment site. The apparatus includes a feedback subsystem to detect impedance changes in the patient and accordingly adjust the output of the apparatus.
    Type: Grant
    Filed: April 21, 2003
    Date of Patent: September 14, 2004
    Assignee: Biowave Corporation
    Inventors: John Carter, Bradford Siff
  • Publication number: 20040167588
    Abstract: A device for providing noninvasive electrical stimulation of a single acupuncture site for treatment of migraines and/or headaches is disclosed.
    Type: Application
    Filed: March 1, 2004
    Publication date: August 26, 2004
    Inventor: Lawrence E. Bertolucci