Combined With Surgical Tool Patents (Class 623/2.11)
  • Patent number: 10433956
    Abstract: Apparatus and methods are provided including a mitral valve prosthesis. The prosthesis includes an inner support structure having downstream and upstream sections, the upstream section having a cross-sectional area greater than the downstream section. The inner support structure is configured to be positioned on an atrial side of the native valve complex, and to prevent the prosthesis from being dislodged into the left ventricle. A prosthetic valve having prosthetic valve leaflets is coupled to the inner support structure. An outer support structure has engagement arms, downstream ends of the engagement arms being coupled to the inner support structure. The prosthesis is configured such that, upon implantation thereof: downstream ends of the native valve leaflets, downstream ends of the engagement arms, and downstream ends of the prosthetic leaflets, are disposed at a longitudinal distance from one another of less than 3 mm. Other embodiments are also described.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: October 8, 2019
    Assignee: Medtronic Ventor Technologies Ltd.
    Inventors: Yosi Tuval, Ilia Hariton, Igor Kovalsky, Eli Ben-Hamou
  • Patent number: 10426607
    Abstract: An apparatus for replacement a native heart valve is herein provided. The apparatus includes a replacement heart valve, an expandable anchor, and a plurality of rivets. The expandable anchor comprises a woven braid structure that surrounds at least a portion of the replacement heart valve and has a plurality of braid intersections. At least some of the braid intersections have rivets extending therethrough.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: October 1, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Peter W. Gregg, Jianhua Yang, Jarad Waisblatt, Benjamin T. Sutton, Ali Salahieh
  • Patent number: 10426619
    Abstract: An implant for improving coaptation of an atrioventricular valve in which the atrioventricular valve has a first native leaflet, a second native leaflet and an annulus includes a support structure configured to be arranged on and fixed to the annulus or to at least one of the first and second native first leaflets. The implant also includes flexible retention structure mounted to the support structure so as to prevent prolapse of the at least one of the first and second native leaflets. A method for improving coaptation of such an atrioventricular valve is also disclosed.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: October 1, 2019
    Assignee: AVVIE GMBH
    Inventor: Werner Mohl
  • Patent number: 10413405
    Abstract: An implantable prosthetic valve has an upper frame section and a lower frame section. The upper frame section has a plurality of struts and a first leaflet receiving surface at a lower portion of the upper frame section. The lower frame section has a second leaflet receiving surface at an upper portion of the lower frame section. An edge of a flexible leaflet is disposed between the first and second leaflet receiving surfaces to attach the leaflet to the upper and lower frame sections.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: September 17, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventor: Netanel Benichou
  • Patent number: 10405974
    Abstract: A replacement heart valve implant may include an expandable anchor member, a plurality of valve leaflets disposed within the anchor member, a seal member disposed about a distal portion of the anchor member, one or more whip sutures attaching a distal end of the seal member to a distal end of the plurality of valve leaflets at a joint, one or more distal lashing sutures attaching a distal portion of the seal member to a distal end of the anchor member, and a plurality of proximal lashing sutures attaching a proximal portion of the seal member to the distal portion of the anchor member, wherein the one or more distal lashing sutures does not extend through the seal member.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: September 10, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Michael Hayes
  • Patent number: 10398546
    Abstract: A mitral valve prosthesis and methods for implanting the prosthesis transapically (i.e., through the apex of the heart), transatrially (i.e., through the left atrium of the heart), and transseptally (i.e., through the septum of the heart). The prosthesis generally includes a self-expanding frame and two or more support arms. A valve prosthesis is sutured to the self-expanding frame. Each support arm corresponds to a native mitral valve leaflet. At least one support arm immobilizes the native leaflets, and holds the native leaflets close to the main frame.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: September 3, 2019
    Assignee: MEDTRONIC VENTOR TECHNOLOGIES LTD.
    Inventor: Yossi Tuval
  • Patent number: 10398550
    Abstract: A delivery device (10) for a collapsible prosthetic heart valve may include an operating handle (20, 220, 320) having a housing (30, 230, 330) and a carriage selectively (40) fixed or movable relative to the housing, and a catheter assembly (16, 116, 216, 416). The catheter assembly may have an inner shaft (26, 126, 226, 326, 426) around which a compartment (23) is defined, an outer shaft (22) surrounding at least a portion of the inner shaft, a distal sheath (24) fixedly connected to the outer shaft, and a mechanism configured to apply a distal force to the outer shaft while the carriage (40) is fixed relative to the housing (30, 230, 330) to stretch the outer shaft from a compressed length to an extended length. The extended length may be greater than the compressed length along an axis of elongation of the outer shaft (22).
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: September 3, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Aaron J. Chalekian, Ralph J. Thomas, Gary W. Geiger
  • Patent number: 10398547
    Abstract: An implant with anchoring device for heart valve disease comprises a cardiac valve prosthesis (1), at least two sets of anchoring needles (2) and at least two sets of anchoring needle releasing devices (3). Proximal end of the anchoring needles (2) are provided with anti-disengagement ends (23). The anchoring needle releasing devices (3) are detachably connected to the cardiac valve prosthesis (1). The anchoring needle releasing devices (3) comprise delivery tubes (31) and shafts (32). Distal sections of the anchoring needle releasing devices (3) are in preset shapes. The shafts (32) can be pushed to force the anchoring needles (2) to move toward the distal ends of the delivery tubes (31), so that the cardiac valve prosthesis (1) is fixed between autogenous tissue (6) and the anti-disengagement ends (23) to achieve accurate positioning and firm anchoring of the cardiac valve prosthesis (1).
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: September 3, 2019
    Assignee: NINGBO JENSCARE BIOTECHNOLOGY CO., LTD.
    Inventors: Jianan Li, Shiwen Lv, Zhiyun Xu, Yibin Li, Zhi Chen
  • Patent number: 10398549
    Abstract: A method for delivering a platform for reinforcing an annulus of a mitral valve: Passing a catheter having a sheath covering a tube formed from a metal into the left atrium, the tube including: an annular portion defining at least one opening, a plurality of upper elements attached to an upper perimeter of the annular portion and extending axially, and a plurality of lower elements attached to a lower perimeter of the annular portion. Inserting the tube into the annulus of the mitral valve; withdrawing the sheath, but leaving the sheath covering the annular portion and the upper elements; bending the lower elements until the lower elements extend radially so as to be positioned beneath the mitral valve; then withdrawing the sheath from covering the annular portion and the upper elements; bending the upper elements until the upper elements extend radially so as to be positioned above the mitral valve.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: September 3, 2019
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Ryan T. Krone
  • Patent number: 10398551
    Abstract: The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: September 3, 2019
    Assignee: Transmural Systems LLC
    Inventor: Nasser Rafiee
  • Patent number: 10390950
    Abstract: A delivery device for a collapsible prosthetic heart valve includes an inner shaft having a proximal end and a distal end, an outer shaft disposed around the inner shaft and longitudinally moveable relative to the inner shaft, and a distal sheath disposed about a portion of the inner shaft and forming a compartment with the inner shaft, the compartment being adapted to receive the prosthetic heart valve. At least one of the outer shaft or the distal sheath may have a pattern of cutouts formed therein, the pattern including at least one ring around a circumference of the at least one of the outer shaft or the distal sheath, the at least one ring having at least one of the cutouts.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: August 27, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Ralph Joseph Thomas, Sounthara Khouengboua, Thomas Mark Benson, Brett Allen Hillukka
  • Patent number: 10390944
    Abstract: A braided support structure that folds upon release from a delivery device wherein said fold is at least partially effected by varying the pic angle of the braids at locations where the folding is desired.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: August 27, 2019
    Assignee: HLT, Inc.
    Inventor: Lucas Harder
  • Patent number: 10390943
    Abstract: Valve devices for replacement of mitral valves while preserving valvular and subvalvular mitral valve apparatus. The valve device may be configured as a double orifice valve replacement device, and may include an anchoring and manifold assembly coupleable to a delivery catheter. The assembly may include means for anchoring the device to the mitral valve or to a fixation device already attached to the mitral valve. A peripheral ring anchoring system secured to the assembly may include at least one expandable anchoring ring that is expandable within an orifice of the mitral valve so as to surround the orifice perimeter. A helical suture may be helically disposable about the ring, securing the ring to adjacent leaflet tissue. A trap door valve including a trap door body that seals against the anchoring ring during systole and unseals during the diastolic portion of the cardiac cycle may be provided.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: August 27, 2019
    Assignee: EVALVE, INC.
    Inventor: Carlos G. Hernandez
  • Patent number: 10383575
    Abstract: Minimally-invasive surgical procedures for monitoring physiological parameters within internal organs of living bodies, and anchors therefor. Such an anchor may have a tubular portion defining a distal end of the anchor, a disk-shaped portion having a proximal surface at a proximal end of the anchor, and an internal passage within the tubular and disk-shaped portions for receiving a sensing device. The internal passage has a proximal portion and an oppositely-disposed distal portion that defines a distal opening in the tubular portion that is configured to retain the sensing device within the internal passage, in combination with one or more features at the proximal end of the anchor. One or more features are defined on the disk-shaped portion for securing the anchor to the wall of the internal organ.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: August 20, 2019
    Assignee: Integrated Sensing Systems, Inc.
    Inventors: Nader Najafi, Catherine Hook Morgan-Leonard
  • Patent number: 10383728
    Abstract: A method for delivering a prosthetic valve to a patient's heart having a native valve with a plurality of valve leaflets includes providing a delivery device with a prosthetic valve, advancing the delivery device toward the native valve, and expanding a portion of the prosthetic valve to form a flanged region that is upstream of the valve leaflets. One or more tabs on the prosthetic valve are released so that they expand outward to a position that is transverse to the longitudinal axis of the prosthetic valve. The position of the prosthetic valve is adjusted relative to the valve leaflets and rapid pacing is applied to the patient's heart so that the valve leaflets move inward toward the prosthetic valve or the delivery device. The tabs are further released to allow the tabs to move into their final positions.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: August 20, 2019
    Assignee: Neovasc Tiara Inc.
    Inventors: Randy Matthew Lane, Alexei J. Marko, Colin A. Nyuli, Krista L. Neale
  • Patent number: 10376365
    Abstract: The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: August 13, 2019
    Assignee: Middle Peak Medical, Inc.
    Inventor: Alexander K. Khairkhahan
  • Patent number: 10376362
    Abstract: Valve introducer systems and methods for implanting heart valve prostheses are disclosed, where a valve introducer includes an adjustable deployment mechanism comprising a deployment element and an implantation depth controlling element having a distal end and an adjustable length. The valve introducer also includes a tubular member having a distal end, configured to deliver a heart valve prosthesis, and a length extending from a fixed reference point. The implantation depth controlling element can comprise an inner and an outer cylinder, such as where the outer cylinder has interior threads, and the inner cylinder has exterior threads. The adjustable deployment element can include a depth gauge, wherein the depth gauge indicates the length the tubular member extends beyond a fixed reference point. In certain embodiments, the adjustable deployment element can also be configured to be secured to a cannula.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: August 13, 2019
    Assignee: Medtronic Vascular Galway
    Inventors: Declan Costello, Ronan Rogers, Edmond Sheahan, Damian Carr
  • Patent number: 10376358
    Abstract: A device for joining individual leaflets for repairing a cardiac valve of a patient has a base and projection fingers rising from the base to support adjacent leaflets for tacking together by sewing overlapping edges of adjacent leaflets prior to emplacement into the patient. The invention provides a cutting tool for excising leaflets from a pericardial tissue sheet according to predetermined sizes and shapes. A leaflet having a desired contour and size is obtained by pressing the tool formed as a cutter block against the tissue sheet. A set of blocks can be provided wherein each cutter block has an outer edge following a respective contour and size for a leaflet, and wherein the outer edge includes a raised cutting edge for pressing through the pericardial tissue sheet. The blocks can be held in a press for assisting in pushing the cutting edge through the tissue.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: August 13, 2019
    Assignee: TERUMO CARDIOVASCULAR SYSTEMS CORPORATION
    Inventors: Matthew W. Graybill, Randal J. Kadykowski, Kevin R. Line
  • Patent number: 10368975
    Abstract: A device for treating acid reflux comprising a sleeve configured and dimensioned for insertion into the esophagus of the patient, the sleeve having a proximal portion, a distal portion and an intermediate portion between the distal and proximal portions. The sleeve includes a an inner member applying a radial force on the sleeve for securement within the esophagus, and a skirt connected to the sleeve to block acid backup from the stomach while not inhibiting passage of food into the stomach.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: August 6, 2019
    Assignee: Rex Medical, L.P.
    Inventor: James F. McGuckin, Jr.
  • Patent number: 10368986
    Abstract: A system for percutaneous delivery of a stented prosthetic heart valve. The system includes a delivery device with a self-expanding prosthetic heart valve attached thereto and a delivery sheath with an opening on a distal end thereof. The delivery sheath includes a funnel on a proximal end thereof. The delivery device is inserted into the funnel of the delivery sheath. As the delivery device is advanced into the funnel, the expanded heart valve is compressed by the shape of the funnel into a crimped arrangement. The delivery device further advances the heart valve distally within the delivery sheath past the delivery sheath opening. The delivery device is advanced relative to the delivery sheath in transitioning the heart valve from a crimped arrangement to the expanded and deployed arrangement.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: August 6, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Devin Gosal, Susheel Deshmukh, Philip Haarstad, Joel Racchini, Finn Rinne, Paul Rothstein, Jeffrey Sandstrom
  • Patent number: 10363137
    Abstract: Apparatuses and devices usable for annuloplasty are provided. These can include a plurality of tissue anchors and an annuloplasty structure for placement on a heart valve annulus. The annuloplasty structure can include a plurality of compressible or adjustable subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible/adjustable subunits. The anchor mounts are coupleable to the tissue anchors and can define a path for passage therethrough of a respective tissue anchor. The apparatuses and devices can be independently adjustable and can be adjustable for treating various sizes of patient annuli. Other embodiments are also described.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: July 30, 2019
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 10363135
    Abstract: In some embodiments, an apparatus includes a catheter assembly and a handle assembly that can be removably coupled to the catheter assembly. A valve holding tube defines a lumen configured to receive a prosthetic mitral valve in a compressed configuration and can be removably coupled to a distal end portion of the handle assembly. The valve holding tube can be received within a hub of the catheter assembly when coupled to the handle assembly. The actuator when actuated is configured to cause the tensioning unit to travel along a traveler strap of the catheter assembly moving the handle assembly distally such that a distal end of an elongate shaft of the handle assembly moves the prosthetic mitral valve distally out of the valve holding tube and out a distal end of the sheath such that the prosthetic mitral valve is free to move to a biased expanded configuration.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: July 30, 2019
    Assignee: Tendyne Holdings, Inc.
    Inventors: Zachary J. Tegels, Robert M. Vidlund
  • Patent number: 10357351
    Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is located distally to the valve. A removable tab is disposed between the distal end of the frame and the nose cone. The tab assists in maintaining the position of the nose cone relative to the distal end of the frame.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: July 23, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Alexander H. Cooper, Michael R. Bialas, David M. Taylor, Gregory Scott Tyler, II, Zachary R. Kowalski, Art Z. Kwan, Darshin S. Patel, Asher L. Metchik, Michael J. Popp, Amanda K. Anderson
  • Patent number: 10357183
    Abstract: A retained object tag, and a method of detecting the presence of a retained object or the retained object tag in a medical image. The method can include different steps such as identifying one or more potential sites in the medical image where the retained object or retained object tag may be present. The method can also include analyzing one or more features of the identified potential site against one or more predetermined properties of the retained object or the retained object tag. And the method can include determining whether the identified potential site is a retained object or a retained object tag based in part or more upon the analyzed feature.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: July 23, 2019
    Assignee: The Regents of the University of Michigan
    Inventors: Theodore Marentis, Nikolaos Chronis, Anurag Tripathi, Heang-Ping Chan, Lubomir Hadjiyski, Amrita Ray Chaudhury, Lucas James Rondon
  • Patent number: 10357366
    Abstract: Apparatuses and devices usable for annuloplasty are provided. These can include a plurality of helical tissue anchors and an annuloplasty structure for placement on a heart valve annulus. The annuloplasty structure can include a plurality of compressible or adjustable subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible/adjustable subunits. The anchor mounts are coupleable to the helical anchors and can define a path for passage therethrough of a respective helical tissue anchor. The apparatuses and devices can be independently adjustable and can be adjustable for treating various sizes of patient annuli. Other embodiments are also described.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: July 23, 2019
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 10357361
    Abstract: Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. The two elements can clamp/pinch the heart valve leaflets to hold the prosthetic heart valve in place. The pinch device can have a flexible, expandable annular frame. A combined delivery system can deliver the pinch device and prosthetic heart valve with just a single access point and aid more accurate coaxial deployment. The pinch device can be mounted near distal end of an access sheath, and a catheter for delivering the prosthetic heart valve can be passed through a lumen of the same access sheath.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: July 23, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Hamid Rafi, Russell T. Joseph, Robert Bowes, Uy D. Trinh, Emil Karapetian, Gregory Bak-Boychuk
  • Patent number: 10350065
    Abstract: A method for delivering a heart valve prosthesis to a native valve annulus comprises expanding an expandable frame at the native valve annulus and positioning a replacement heart valve within the expandable frame. The expandable frame preferably includes a first anchoring portion that is positioned on a first side of the native valve annulus and a second anchoring portion that is positioned on a second side of the native valve annulus. The first anchoring portion engages tissue on the first side of the native valve annulus and the second anchoring portion engages tissue on the second side of the native valve annulus for securing the expandable frame to the native valve annulus. The replacement heart valve comprises a plurality of leaflets for replacing the function of the native valve.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: July 16, 2019
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventor: Arshad Quadri
  • Patent number: 10350064
    Abstract: An assembly and methods for providing a contoured biological tissue are described. The assembly comprises a first plate and a second plate. The first plate is configured to receive a biological tissue. The second plate is configured to contact and compress the biological tissue received on the first plate. One or both of the first and second plates comprise a defined shape and a contoured area within the defined shape. The contoured area comprises at least first and second elevations. One or more energy sources are associated with one or both of the first and second plates. The one or more energy sources deliver energy upon compression of the biological tissue.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: July 16, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Amy E. Munnelly, Jeffrey S. Dove, Minsey Lee
  • Patent number: 10350390
    Abstract: A system for conducting denervation of the neural plexus adjacent the renal artery, comprises a pre-shaped ablative element operatively coupled to an elongate deployment member configured to be navigated into the renal artery, the pre-shaped ablative element comprising one or more RF electrodes disposed in an arcuate pattern; and an energy source operatively coupled to the one or more RF electrodes and being configured to cause current to flow from the pre-shaped ablative element and cause localized heating sufficient to denervate nearby neural tissue.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: July 16, 2019
    Assignee: Auris Health, Inc.
    Inventors: Frederic H. Moll, Randall L. Schlesinger, Farzad Soleimani, Daniel T. Wallace
  • Patent number: 10335274
    Abstract: A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window for enhanced access to the commissure posts and leaflets. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation.
    Type: Grant
    Filed: July 11, 2015
    Date of Patent: July 2, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Alain F. Carpentier, Michael C. Murad
  • Patent number: 10335271
    Abstract: Systems, dies, and methods are provided for processing pericardial tissue. The method includes positioning a die-cut assembly over the pericardial tissue, the die-cut assembly including a die having a plate, a the pattern, and an opening, the die pattern attached to the plate, the opening formed in the plate to provide access to the pericardial tissue, and measuring a thickness of the tissue through the opening. The die-cut assembly may be mounted for automated vertical movement, and a platen on which the tissue is placed is capable of automated horizontal movement. Different target areas on the tissue can be assessed by measuring the thickness through the die, and when an area is deemed suitable the die pattern cuts a shape therefrom. The system is useful for cutting uniform thickness heart valve leaflets, and can be automated to speed up the process.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: July 2, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Oanh H. Nguyen, Ivan Jankovic, Diana Nguyen-Thien-Nhon, Juan C. Velez, Jon Boomgarden
  • Patent number: 10321995
    Abstract: The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular an orthogonally delivered transcatheter prosthetic valve having a tubular frame with a flow control component mounted within the tubular frame and configured to permit blood flow in a first direction through an inflow end of the valve and block blood flow in a second direction, opposite the first direction, through an outflow end of the valve, wherein the valve is compressible to a compressed configuration for introduction into the body using a delivery catheter for implanting at a desired location in the body, said compressed configuration having a long-axis oriented at an intersecting angle of between 45-135 degrees to the first direction, and expandable to an expanded configuration having a long-axis oriented at an intersecting angle of between 45-135 degrees to the first direction, wherein the long-axis of the compressed configuration of the valve is substantially parallel to a length-wise cylindrical axis of
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: June 18, 2019
    Assignee: VDYNE, LLC
    Inventors: Mark Christianson, Robert Vidlund, Neelakantan Saikrishnan, David Holtan, Craig Ekvall
  • Patent number: 10314698
    Abstract: A structure for sealing a gap between a medical device and adjacent body tissue includes a ring-shaped body formed at least in part of a material that expands from a compressed condition to an expanded condition when heated to a transition temperature and that is adapted to conform to the body tissue in the expanded condition.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: June 11, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Benedict Skemp, Edward E. Parsonage, Tracee Eidenschink, Aditee Kurane
  • Patent number: 10299920
    Abstract: The invention relates to a medical implant, comprising an expandable structure (100) which is designed to be expanded from a crimped state into an expanded state, wherein the structure (100) forms a tubular scaffolding in the expanded state, and wherein the structure (100) comprises a plurality of first struts (101) arranged along a periphery of the structure in said expanded state. According to the invention, the first struts (101) each comprise a recess (O), wherein the medical implant (1) further comprises a sealing member (200) arranged in said recesses (O), wherein said sealing member (200) is formed annularly in said expanded state.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: May 28, 2019
    Assignee: UNIVERSITAT ZURICH
    Inventors: Benedikt Weber, Simon Philipp Hoerstrup
  • Patent number: 10292818
    Abstract: A device (100) for the excision of a heart valve via a percutaneous route having a proximal (20) and distal (30) end, comprising an expandable cutting instrument, ECI, that forms a receptacle in the open configuration for receiving, compacting and containing the excised heart valve, an expandable cutting block, ECB, and a displacement mechanism (5, 6) for adjusting the distance between the ECI and the ECB (70).
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 21, 2019
    Assignees: UNIVERSITE CATHOLIQUE DE LOUVAIN, CLINIQUES UNIVERSITAIRES SAINT LUC
    Inventors: Parla Astarci, Khanh Tran Duy, Benoît Raucent, Xavier Bollen, Benoît Herman
  • Patent number: 10292844
    Abstract: A tool for compressing a stented prosthesis. The tool includes first and second sets of rollers. The first set includes a plurality of rollers arranged to define a first working region having a first working diameter. The second set includes a plurality of rollers arranged to define a second working region having a second working diameter. The sets of rollers are arranged such that the working regions are axially aligned. The first working diameter is greater than the second working diameter. A stented prosthesis traversing the first working region and then the second working region is forced to a compressed state. In some embodiments, the tool includes one or more intermediate sets of rollers between the first and second sets of rollers, with each of the intermediate sets of rollers defining a working region having a working diameter. The respective working diameters progressively decrease in a downstream direction.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: May 21, 2019
    Assignee: Medtronic Vascular, Inc.
    Inventors: Geoffrey Orth, Kenny Bruner, Don Tran, Jill Mendelson, James R. Keogh
  • Patent number: 10292842
    Abstract: An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: May 21, 2019
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventor: Jennifer K. White
  • Patent number: 10285811
    Abstract: A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an ex paneled condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shape.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: May 14, 2019
    Assignee: SYMETIS, SA
    Inventors: Fabien Lombardi, Youssef Biadillah, Jean-Luc Hefti, Luc Mantanus, Stéphane Delaloye
  • Patent number: 10285808
    Abstract: Described embodiments are directed toward centrally-opening, leaflet valve devices and systems for transcatheter delivery having a two-piece valve body as well as methods of making and delivering the two-piece valve devices. A transcatheter valve includes a collapsed configuration and an expanded configuration. The transcatheter valve can further include an everted configuration and a non-everted configuration.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: May 14, 2019
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: William C. Bruchman, Cody L. Hartman
  • Patent number: 10278820
    Abstract: Described embodiments include apparatus (20) that includes an assembly of tubes (34), each one of the tubes being shaped to define a tube lumen (62). The apparatus further includes a plurality of tissue anchors (60), each one of the tissue anchors being disposed within a respective one of the tube lumens, an expandable annular structure (36), including a plurality of teeth (40), coupled to the assembly of tubes, and a plurality of control wires (38) coupled to the annular structure, configured to position the tubes for deployment of the tissue anchors from the tube lumens, by manipulating the annular structure. Other embodiments are also described.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: May 7, 2019
    Assignee: Valfix Medical Ltd.
    Inventors: Eli Bar, Elad Yaacoby
  • Patent number: 10278850
    Abstract: A method of inserting a stent includes inserting a unitary, monolithic catheter assembly into a cardiac artery. The catheter assembly includes a body having a proximal end and a distal end, a distal balloon mounted on the distal end, and a proximal balloon mounted on the body, proximally of the distal balloon. A balloon expandable stent is mounted on the distal balloon. The method further includes the steps of advancing the catheter assembly to a blockage in the artery until the distal balloon and the stent both extend across the blockage; inflating the distal balloon and expanding the stent; deflating the distal balloon; advancing the catheter body distally until the proximal balloon extends within the stent; expanding the proximal balloon to post-dilate the stent; deflating the proximal balloon; and withdrawing the catheter body from the artery.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: May 7, 2019
    Assignee: Clever Cath Technologies, LLC
    Inventor: Romeo Majano
  • Patent number: 10271948
    Abstract: Heart valve prosthesis recapture devices and methods for recapture are disclosed, which can be used for recapturing a partially deployed heart valve prosthesis. The recapture device comprises a recapture sleeve, configured to envelop and collapse a partially deployed heart valve prosthesis. The recapture sleeve comprises a distal end, configured to be securely attached to a guide wire, and a proximal end, comprising an opening along a longitudinal axis of the recapture sleeve. The opening can be configured to expand as it engages the heart valve prosthesis, and be biased toward a closed configuration. An attachment element can interface with the distal end of the recapture sleeve and be securely attached to a guide wire, such as by crimping. The recapture sleeve can include a support structure comprising at least one spine and a plurality of ribs.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: April 30, 2019
    Assignee: Medtronic Vascular Galway
    Inventor: Niall Duffy
  • Patent number: 10271950
    Abstract: Embodiments of the present disclosure include a method of transcatheterly delivering a band to encircle multiple papillary muscles in a heart. The method may comprise transcutaneously inserting a catheter into a heart and delivering a first end of a first guidewire to a ventricle in the heart via the catheter. The method may further comprise looping a first end of a first guidewire around a first papillary muscle and a second end of a second guidewire around a second papillary muscle. The first end of the first guidewire and the second end of the second guidewire may be brought out of the body while the first and second guidewires remain looped around the first and second papillary muscles, respectively. The first and second guidewires may be interconnected, and at least one end of the first and second guidewires may be pulled to establish a single loop around the papillary muscles.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: April 30, 2019
    Assignee: Cardiac Success Ltd.
    Inventor: David Neustadter
  • Patent number: 10265169
    Abstract: A prosthetic implant delivery assembly can include a prosthetic implant and an elongate catheter. The prosthetic implant can include an expandable stent portion having a longitudinal axis extending from a first end portion of the stent to a second end portion of the stent. The catheter can include a longitudinal axis extending from a proximal end portion of the catheter to a distal end portion of the catheter and a plurality of arms extending axially from the distal end of the catheter. The first end portion of the stent can be releasably and pivotably coupled to at least one the arms of the catheter such that the stent can pivot about the at least one of the arms so that the longitudinal axis of the stent is tilted relative to the longitudinal axis of the catheter.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: April 23, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: John J. Desrosiers, Amanda K. Anderson, Michael R. Bialas, Gilbert Madrid, Michael J. Popp, Thanh V. Nguyen, Jun Liu, Asher L. Metchik, Darshin S. Patel
  • Patent number: 10258470
    Abstract: A delivery device for a stented heart valve comprises a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: April 16, 2019
    Assignee: Medtronic 3F Therapeutics, Inc.
    Inventors: Andrzej M. Malewicz, Matthew W. Weston, David Elizondo, Daniel C. Weber
  • Patent number: 10251749
    Abstract: A delivery system and method for delivery of an annuloplasty implant for a patient are disclosed. The delivery system comprises a commissure locator device for locating a commissure, comprising; an extension member, a catheter, and wherein the extension member is extendable relative the catheter for location of at least one commissure of a cardiac valve, and a coronary sinus contractor for temporary insertion into the coronary sinus (CS) and having a displacement unit being temporarily transferable to an activated state in which the shape of the annulus of the heart valve is modified to a modified shape to be retained by said annuloplasty implant.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: April 9, 2019
    Assignee: Medtentia International Ltd Oy
    Inventors: Hans-Reinhard Zerkowski, Olli Keränen, Ger O'Carroll, Mark Pugh, Adrian Moran
  • Patent number: 10238491
    Abstract: A method is provided for repairing the tricuspid valve of a patient using tension. A radially-expandable stent is implanted in a coronary sinus of the patient. A tissue anchor is implanted in tissue in the vicinity of the tricuspid valve. The tricuspid valve is repaired by applying tension between the radially-expandable stent and the tissue anchor using a flexible longitudinal member that connects the radially-expandable stent and the tissue anchor.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: March 26, 2019
    Assignee: 4TECH INC.
    Inventors: Idan Tobis, Francesco Maisano, Hugo Vanermen, Valery Perevalov, Rephael Hof
  • Patent number: 10231834
    Abstract: A low profile transseptal catheter and implant system is disclosed. Access to the mitral valve can be obtained using femoral catheterization with a fluoroscopically guided, low-profile catheter. For example, the right atrium is accessed and the interatrial septum punctured to access the left atrium, and the mitral valve is approached through the left atrium. Advantageously, this approach avoids contact with the left ventricular outflow tract and the chordae tendinae. Two leaflet braces are extended over guide wires to form semicircular loops that circumnavigate the anterior and posterior mitral valve leaflets. Tension is applied to the catheter from the atrial direction to keep the leaflet braces tightly wedged under the leaflets for the remainder of the procedure. A fastener joins the ends of each loop to create one annular ring encircling the valve under the anterior and posterior leaflets.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: March 19, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventor: Yaron Keidar
  • Patent number: 10231832
    Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: March 19, 2019
    Assignee: Medtronic, Inc.
    Inventors: Padraig Savage, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Michael Krivoruchko
  • Patent number: 10231837
    Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a pair of paddles and a pair of gripping members. The paddles are movable between an open position and a closed position. The paddles and the gripping members are configured to attach to the native valve of the patient. The paddles are biased to the closed position, latched to the gripping members in the closed position, maintained in the closed position by a threaded connection, or otherwise maintained in the closed position.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: March 19, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Asher L. Metchik, Gregory Scott Tyler, II, Matthew T. Winston, Sergio Delgado, Lauren R. Freschauf, Eric R. Dixon, Alexander J. Siegel