Combined With Surgical Tool Patents (Class 623/2.11)
  • Patent number: 10806577
    Abstract: Atrio-ventricular valve stent (1) having a tubular shape, with a sub annular anterior side (2), a sub annular posterior side (3) and sub annular lateral sides (13), the sub annular anterior side (2) comprising a self-folding native leaflet engagement member (4-9) that forms a straight extension of said sub annular anterior side (2) when the stent (1) is collapsed and that is folded on itself when the stent (1) is in an expanded state; said engagement member (4-9) forming an integral part of the stent (1) and wherein each sub annular lateral side (13) is longer than said sub annular anterior side (2) when the stent (1) is in an expanded state.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: October 20, 2020
    Assignee: Epygon
    Inventors: Enrico Pasquino, Marcio Scorsin, Stefano Pasquino, Andrea Marchisio, Lorenzo Valerio, Sergio Casalegno, Marco Gard, Pietro Arru
  • Patent number: 10806575
    Abstract: A delivery assembly includes a prosthetic device, a catheter shaft, a release wire, a first line, and a second line. The prosthetic device has a first arm and a second arm. The release wire extends through the catheter shaft. The first line includes a first loop. The first line extends from the catheter shaft, through the first arm of the prosthetic device, and to the release wire, where the release wire extends through the first loop. The second line includes a second loop. The second line extends from the catheter shaft, through the second arm of the prosthetic device, and to the release wire, where the release wire extends through the second loop.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: October 20, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Alon, Netanel Benichou, Oded Robert Meiri
  • Patent number: 10799357
    Abstract: A surgical instrument implementing a leaflet grabbing mechanism by a leaflet grabbing structure, in which the leaflet can be grabbed and clamped between first and second abutment surfaces. The first, proximally facing abutment surface belongs to a swivel-out portion of the leaflet grabbing structure, which includes at least a first arm and a second arm. In a released state, when the leaflet grabbing structure is released from a catheter, the arms are capable of swiveling: the first arm may swivel with respect to a main body to which it is attached, and the second arm may swivel relative to the first arm so that in a leaflet grabbing position the first abutment surface faces proximally. The second arm includes a recess arranged so that a chord extending between a released distal implant part and a proximal implant part can extend therethrough and be released by a lateral relative movement.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: October 13, 2020
    Assignee: COREMEDIC AG
    Inventors: Silvio Schaffner, Tobias Aeschlimann, Oliver Wüthrich, Thomas Bauer
  • Patent number: 10799242
    Abstract: Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and/or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: October 13, 2020
    Inventors: James E. Coleman, Christy Cummins
  • Patent number: 10799361
    Abstract: A method of treating a defective mitral valve includes inserting a delivery catheter through a small incision in a patient's groin, wherein the delivery catheter has a prosthetic device positioned along a distal end thereof. The prosthetic device includes an insert member and an anchoring member, wherein the insert member is made from a shape memory material and is surrounded by a biocompatible fabric outer layer. The insert member is positioned within a mitral valve and self-expands in a gap between the native leaflets. The anchoring member is attached to surrounding tissue. After deployment of the prosthetic device, the native leaflets of the mitral valve form a tight seal against the biocompatible fabric outer layer and the insert member fills the gap between the native leaflets of the mitral valve for preventing regurgitation during ventricular systole.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: October 13, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: David L. Hauser, Jan Otto Solem, David Alon
  • Patent number: 10792151
    Abstract: Systems for delivering prosthetic heart valve devices can include, for example, an elongated catheter body, a deliver capsule carried by the catheter body, and an expandable atraumatic member. The delivery capsule includes a platform and a housing having an outer wall and a proximal rim, and the platform is configured to be releasably coupled to a prosthetic heart valve device. The housing is configured to slide along the platform from a containment configuration to a deployment configuration. The expandable atraumatic member has an atraumatic surface and a peripheral portion. The atraumatic member has a compacted configuration and an expanded configuration in which the peripheral portion extends laterally outward over the proximal rim of the housing to protect tissue of the heart and the vasculature from potentially being damaged by the proximal rim of the housing as the delivery system is withdrawn in a proximal direction through the patient.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: October 6, 2020
    Assignee: TWELVE, INC.
    Inventors: Kevin Mauch, Joshua Dwork, Finn Rinne, Siyan Som, Estella Wong
  • Patent number: 10786356
    Abstract: A cardiac valve annulus may be constricted by using an apparatus to deliver a cord to the annulus, affixing the cord, and subsequently tightening that cord. In some embodiments, this apparatus includes an elongated core with a main channel, a set of first channels, and at least one second channel, all of which run through the core. The first channels accommodate pull wires for triggering the anchor launchers, and the second channels accommodate portions of the cord. Support arms extend distally beyond the core, and anchor launchers are mounted to each of these support arms. The support arms hold the distal ends of the anchor launchers at positions distributed about the annulus. The anchors are launched to affix the cord, and the cord is tightened in a subsequent procedure.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: September 29, 2020
    Assignee: Cardiac Implants LLC
    Inventor: David Alon
  • Patent number: 10779942
    Abstract: The present disclosure relates to numerous delivery devices and methods for transcatheter prosthetic heart valve loading, deployment and delivery utilizing at least one suture. Disclosed delivery devices utilize improved suture routing methods and configurations that reduce suture tangling and also provide the ability to adjust the prosthetic heart valve expansion and contraction prior to the final release of the prosthetic heart valve from the delivery device.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: September 22, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventor: Paul Rothstein
  • Patent number: 10779941
    Abstract: A delivery cylinder for a prosthetic implant can include a first tubular portion and a second tubular portion. The second tubular portion has a plurality of strut members coupled to the first tubular portion that define a volume for containing the prosthetic implant in a radially compressed state. The strut members can include respective flex regions configured such that application of force to the strut members causes deformation of the flex regions and corresponding radially inward or outward movement of the strut members relative to a longitudinal axis of the delivery cylinder between an expanded configuration and a contracted configuration.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: September 22, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Arvin T. Chang, Sam Sok, Amanda K. Anderson, Ajay Chadha
  • Patent number: 10772725
    Abstract: An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: September 15, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Michael C. Murad, Emil Karapetian, Wesley V. Adzich
  • Patent number: 10772726
    Abstract: This treatment device (10) for a biological valve includes: an implant (12) having a proximal sleeve (14), deployable between a retracted configuration and a deployed configuration, and comprising a plurality of proximal arms (32) intended to bear on a first face of a leaflet (18) or on an annulus (17) of the valve, a release tool (14) for releasing the implant (12), the implant (12) being mounted in the release tool (14) in its retracted configuration. The device (10) comprises a pushing member (16) for pushing the face of the valve leaflet (18) away from a free end of the proximal arms (32), movable relative to the implant (12) kept in its configuration retracted in the release tool (14) between a withdrawn position and a deployed position pushing the face of the leaflet (18).
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: September 15, 2020
    Assignee: LABORATORIES INVALV
    Inventor: Eric Perouse
  • Patent number: 10765511
    Abstract: The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular a device and method for percutaneous annular plication and heart valve deployment for mounting a pressure actuated flow control sleeve, a pinch valve, as a replacement device for a heart valve, whereby the prosthesis has an atrial annular flange or cuff having one or more integral plication tissue anchors for engaging the valve annulus, wherein the is a reciprocating mechanical member that is compressed by pressurized working fluid within the heart during ventricular systole.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: September 8, 2020
    Assignee: VDYNE, INC.
    Inventors: Robert Vidlund, Mark Christianson, David Holtan
  • Patent number: 10765514
    Abstract: Apparatus is provided including a percutaneously-implantable implant and an adjustment device. The adjustment device can comprise an adjustment mechanism, coupled to the implant, and configured to change a dimension of the implant upon actuation of the adjustment mechanism and a lock. The adjustment device can have a locked state in which the lock inhibits actuation of the adjustment mechanism and an unlocked state in which the adjustment mechanism is actuatable. The adjustment device can be reversibly movable between the locked state and the unlocked state. The apparatus can include a longitudinal guide member and an adapter. An unlocking mechanism can be configured such that, while the adapter is coupled to the adjustment device, actuation of the unlocking mechanism moves the lock between the locked state and the unlocked state. Other applications are also described.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: September 8, 2020
    Assignee: Valtech Cardio, Ltd.
    Inventors: Ehud Iflah, Tal Reich, Tal Sheps, Ilia Hariton, Haim Brauon, Meir Kutzik, Alexei Koifman, Yaron Herman
  • Patent number: 10758346
    Abstract: The invention relates to an A2 clip for a side-delivered prosthetic mitral valve where the A2 clip is extended using a guide wire to capture native mitral leaflet and/or chordae tissue and withdrawing the guide wire contracts the A2 clip and pins the native tissue against the subannular sidewall of the prosthetic valve.
    Type: Grant
    Filed: June 16, 2019
    Date of Patent: September 1, 2020
    Assignee: VDYNE, INC.
    Inventors: Mark Christianson, Robert Vidlund, Scott Kramer
  • Patent number: 10758265
    Abstract: A system and method of accessing a heart of a patient is provided. A cardiac access channel is established through an apical wall of the heart to provide direct access through the apical wall to the left ventricle. A vascular access channel is established through the skin to a peripheral blood vessel. A first end of an elongate member is advanced from the outside of the apical wall through the cardiac access channel and into the left ventricle. A second end disposed opposite the first end remains outside the patient. The elongate member is drawn into and through the vascular access channel to externalize the first end of the elongate member while leaving the second end outside the apical wall of the heart.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: September 1, 2020
    Assignee: Cedars-Sinai Medical Center
    Inventor: Robert James Siegel
  • Patent number: 10758347
    Abstract: Described is a delivery system for percutaneous delivery and implantation of a heart valve. The delivery system includes a handle with a sheath extending therefrom. A splay shaft extends from the handle through the sheath. At least two arms extend from the handle through the splay shaft. The at least two arms are operable for holding a heart valve. A sheath controller is housed within the handle and is operable for selectively advancing or retracting the sheath to constrain or expose a heart valve as attached with the at least two arms. A splay shaft controller is housed within the handle for allowing the user to selectively advance or retract the splay shaft to constrain or expose the at least two arms. Finally, a valve release is attached with the handle to allow a user to selectively release a heart valve as attached with the at least two arms.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: September 1, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Arash Kheradvar, Gregory S Kelley
  • Patent number: 10758345
    Abstract: A mitral valve prosthesis includes an expandable frame having a proximal end, a distal end, and a middle portion. A plurality of tips extend from the proximal end of the frame for attachment to a delivery catheter. A plurality of anchors are disposed along the distal end of the frame and extend toward the proximal end for engaging tissue. An outer circumferential portion extends around the middle portion of the frame and is positioned radially outwardly of the frame. The outer circumferential portion preferably increases in diameter along a distal direction. A distal end of the outer circumferential portion is located distal of free ends of the anchors when the expandable frame is deployed. A valve body is positioned within an interior of the expandable frame and includes leaflets adapted to allow flow in a first direction and prevent flow in a second direction.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: September 1, 2020
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: J. Brent Ratz, Luca Pesce, Siddharth Vad, Garrett Dallas Johnson
  • Patent number: 10751175
    Abstract: A valve prosthesis and implantation device, and methods for use are provided. The devices described herein may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device can utilize movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: August 25, 2020
    Assignee: JC Medical, Inc.
    Inventor: Ji Zhang
  • Patent number: 10751181
    Abstract: Methods and apparatuses for regulating aortic regurgitation are provided. A catheter shaft is advanced through vasculature so that a flexible occluding membrane coupled to the catheter shaft is positioned within the aorta, typically the ascending aorta above the Sinus of Valsalva and coronary ostia. Blood flow in the aorta causes the flexible occluding membrane to alternate between an expanded occluding configuration while in diastole and a collapsed lesser occluding configuration is systole. The flexible occluding membrane thereby acts as a temporary aortic valve. The flexible occluding membrane is generally conical in shape, with the tip of the cone disposed closer to the aorta than the proximal rim. In diastole, blood flow expands the flexible occluding membrane so that the proximal rim apposes the inner wall of the aorta. The flexible occluding membrane will have one or more openings to allow perfusion of the coronary arteries in diastole.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: August 25, 2020
    Assignee: HOCOR Cardiovascular Technologies LLC
    Inventor: Paul C. Ho
  • Patent number: 10743987
    Abstract: Methods for delivering a pulmonary or mitral valve prosthesis using a transcatheter approach are provided. The implantation devices can utilize movable claspers for both positioning and anchoring the valve prostheses within the native cardiac valve, minimizing the extent of imaging necessary.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: August 18, 2020
    Assignee: JC Medical, Inc.
    Inventor: Ji Zhang
  • Patent number: 10736739
    Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed on an outer surface of the tubular body, and the fabric having an inflow end and an outflow end, Furthermore, the outflow end of the fabric being directly connected to an outer circumferential edge of the valve.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: August 11, 2020
    Assignee: HIGHLIFE SAS
    Inventor: Malek Nasr
  • Patent number: 10736742
    Abstract: A valve frame is shaped to define a plurality of atrial arms, and a tubular portion that defines a lumen along a longitudinal axis of the valve frame. Prosthetic leaflets within the lumen are coupled to the frame. An outer frame defines a ring and a plurality of ventricular legs coupled to the ring. The ring circumscribes the tubular portion, and is defined by a pattern of alternating peaks and troughs. The tubular portion defines a row of upstream cells, and a row of downstream cells that is tessellated with the row of upstream cells. Each of the atrial arms is attached to, and extends from, a respective connection site at which adjacent upstream cells are connected to each other. Other embodiments are also described.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: August 11, 2020
    Assignee: CARDIOVALVE LTD.
    Inventors: Ilia Hariton, Boaz Harari
  • Patent number: 10729427
    Abstract: The present invention relates to a tissue protection device for mitral valve cerclage annuloplasty and, more particularly to a tissue protection device for protecting tissues of the body (heart) during mitral valve cerclage annuloplasty that is performed on a mitral valve cerclage patient with mitral regurgitation. The tissue protection device for mitral valve cerclage annuloplasty of the present invention is a hollow cylindrical tube where cerclage sutures (10a, 10b) are inserted, in which a hole (22) is formed at a predetermined portion of the cylindrical tube so that a coronary sinus cerclage suture (10a) inserted in a coronary sinus comes out of the cylindrical tube, and a lower section from the hole is inserted into the tricuspid valve to protect tissues of the tricuspid valve and the ventricular septum.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: August 4, 2020
    Assignee: TAUPNU MEDICAL CO., LTD.
    Inventor: June-Hong Kim
  • Patent number: 10722358
    Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: July 28, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Rafael Pintor, Michael J. Scott, Thomas H. Chien, Harvey H. Chen, August R. Yambao, Lawrence J. Farhat, Andrew Phung, William C. Brunnett, Carey L. Cristea, Sara M. Walls, Kevin W. Zheng, Faisal Kalam, Qinggang Zeng
  • Patent number: 10722356
    Abstract: Valve holders and introducers for delivering a prosthetic heart valve to an implant site are in various embodiments configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. A valve holder according to embodiments of the invention includes features that reduce or eliminate mistakes during implantation of the prosthetic valves, for example, a removable activator dial and a removable handle that prevent implantation of the valve prior to proper deployment or adjustment of the holder. An introducer is provided which can facilitate passing of a prosthetic valve between adjacent ribs of a patient. Valve holders and introducers according to the various embodiments can be used in minimally invasive procedures, such as thoracotomy procedures.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: July 28, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian S. Conklin, Derrick Johnson
  • Patent number: 10702381
    Abstract: A heart valve remodeling device may include a delivery device including an inner shaft slidably disposed over a guidewire and an outer shaft slidably disposed over the inner shaft, and a braided stent fixedly attached to the inner shaft and the outer shaft. The braided stent may be translatable between an elongated configuration and a deployed configuration by movement of the inner shaft relative to the outer shaft. The braided stent may include a valve having two or more leaflets disposed within the braided stent. Adjacent leaflets of the two or more leaflets may form longitudinally-oriented commissures proximate a perimeter of the valve, the commissures being fixedly secured to the braided stent along their length.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: July 7, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Tim O'Connor, Pat O'Toole, Richard O'Sullivan, Marc Feeley, Paul Gunning, Fergal Horgan, Coley Smyth, Sean Shanley, Axel Linke
  • Patent number: 10702380
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include a valve support having an upstream end and a downstream end extending around a longitudinal axis and having a cross-sectional shape. The valve support can have an outer surface and an inner surface, wherein the inner surface is configured to support a prosthetic valve. The device can also include an expandable retainer coupled to the upstream end of the valve support. The retainer can be configured to engage tissue on or near the annulus. In some embodiments, the valve support is mechanically isolated from the retainer such that the cross-sectional shape of the valve support remains sufficiently stable when the retainer is deformed in a non-circular shape by engagement with the tissue.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: July 7, 2020
    Assignee: Twelve, Inc.
    Inventors: John Morriss, Hanson Gifford, III, James L. Fann, Jean-Pierre Dueri, Darrin Gittings, Michael Luna, Mark Deem, Douglas Sutton
  • Patent number: 10702379
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: July 7, 2020
    Assignee: Medtronic CV Luxembourg S.a.r.l.
    Inventors: Kshitija Garde, Joel Racchini, Paul Rothstein, Jeffrey Sandstrom
  • Patent number: 10695160
    Abstract: Excessive dilation of the annulus of a mitral valve may lead to regurgitation of blood during ventricular contraction. This regurgitation may lead to a reduction in cardiac output. Disclosed are systems and methods relating to an implant configured for reshaping a mitral valve. The implant comprises a plurality of struts with anchors for tissue engagement. The implant is compressible to a first, reduced diameter for transluminal navigation and delivery to the left atrium of a heart. The implant may then expand to a second, enlarged diameter to embed its anchors to the tissue surrounding and/or including the mitral valve. The implant may then contract to a third, intermediate diameter, pulling the tissue radially inwardly, thereby reducing the mitral valve and lessening any of the associated symptoms including mitral regurgitation.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: June 30, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Randall Lashinski, Matthew Rust, Patrick Macaulay, Terry Wayne Daniels, Kris Kristoffersen
  • Patent number: 10695176
    Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: June 30, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: George Bakis, Thanh V. Nguyen, Ly Th Phan, Asher L. Metchik
  • Patent number: 10687896
    Abstract: A method for surgical resection planning of a mass includes the steps of, modelling the mass based on a plurality of physical dimensions, determining a plurality of safety margins around a plurality of features within the mass, simulating a resection surface on the mass that includes a plurality of triangles, optimizing local area and position of a first of the plurality of triangles on the resection surface based on a triangle-based algorithm, updating the simulation of the resection surface, and repeating the steps of optimizing and updating for each of the plurality of triangles on the resection surface.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: June 23, 2020
    Assignees: Agency for Science, Technology and Research, National University Hospital (Singapore) Pte Ltd.
    Inventors: Wenyu Chen, Sudhakar K. Venkatesh, Qi Tian, Jianyin Zhou, Weimin Huang, Wei Xiong, Oo Thiha
  • Patent number: 10687940
    Abstract: A prosthetic cardiac valve implantation arrangement is described. The prosthetic cardiac valve implantation arrangement includes a prosthesis catheter with a prosthetic cardiac valve to be implanted; and an ICE catheter for introduction into area surrounding a cardiac valve to detect a relative position and/or relative direction of orientation of the cardiac valve with respect to the ICE catheter with the aid of an ultrasound image of the cardiac valve recorded by the ICE catheter. In addition, a navigation system is for determining an absolute position and an absolute direction of orientation of the ICE catheter; and a control facility is for controlling the insertion of the prosthetic cardiac valve into the annulus of the cardiac valve on the basis of the ultrasound image recordings of the ICE catheter and positional and/or orientation-direction information from the navigation system. Also described is a method for monitoring a catheter-based prosthetic cardiac valve implantation.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: June 23, 2020
    Assignee: SIEMENS HEALTHCARE GMBH
    Inventor: Stefan Assmann
  • Patent number: 10682494
    Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal member having a proximal end, a distal end, and a proximal diameter. The guide extension catheter may additionally include a collar member attached to the distal end of the proximal member, the collar member comprising a base portion and one or more ribs connected to the base portion and extending distally away from the base portion. In still some additional embodiments, the guide extension catheter may further include a distal sheath member attached to the collar member, the distal sheath member having a distal diameter larger than the proximal diameter.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: June 16, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Jeffrey Steven Fuller, James M. Anderson, John E. Uschold
  • Patent number: 10682229
    Abstract: A method of treating a heart of a patient is provided. The method includes implanting a first tissue anchor in cardiac tissue of the patient and a second tissue anchor in the patient, such that the first and the second tissue anchors are coupled together by one or more tethers. Thereafter, after allowing at least 24 hours for tissue growth on the first tissue anchor to strengthen anchoring of the first tissue anchor in the cardiac tissue, tension is applied between the first and the second tissue anchors using at least a longitudinal portion of the one or more tethers. Other embodiments are also described.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: June 16, 2020
    Assignee: 4Tech Inc.
    Inventors: Andrea Guidotti, Idan Tobis, Kevin Lynn, Chris Moran, Michael Gilmore
  • Patent number: 10682227
    Abstract: Embodiments of the present disclosure are directed to prosthetic valves and methods of use thereof. In one implementation, an annular valve body may include a plurality of atrial anchoring arms and ventricular anchoring legs configured to extend therefrom. The anchoring arms and anchoring legs may be configured to assume a delivery configuration in which they are substantially parallel to a longitudinal axis of the valve body, and a deployed configuration, in which they may deflect radially outward. The anchoring arms may include a pivoting portion configured to extend in a non-ventricular direction when the arm is in the delivery configuration and in a ventricular direction when the arm is in the deployed configuration. The entire length of each leg may be configured to extend in a non-ventricular direction when the legs are in both the delivery and deployed configurations.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: June 16, 2020
    Assignee: CARDIOVALVE LTD.
    Inventors: Ilia Hariton, Boaz Harari
  • Patent number: 10675149
    Abstract: A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: June 9, 2020
    Assignee: Medtronic, Inc.
    Inventors: Michael J. Drews, Donnell W. Gurskis, Stephen R. Bacich
  • Patent number: 10667914
    Abstract: The devices and methods described herein may be used to restore left ventricular function to address mitral valve regurgitation. One variation of an implant comprises a plurality of tethered anchors and a plurality of force-distribution members slidably disposed on the tether between the anchors. One or more of the force-distribution members can comprise a bioabsorbable material. Methods comprise deploying the implant to cardiac tissue, cinching the implant to its hard stop (e.g., where further cinching does not cause further tissue tightening), providing a pre-selected amount of slack to the implant after it has been cinched to its hard stop configuration, and securing a lock member on the tether. Also disclosed herein are lock member deployment catheters that provide a pre-selected amount of tether slack as it secures a lock member on the tether.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: June 2, 2020
    Assignee: Ancora Heart, Inc.
    Inventors: Russel Sampson, Jennifer Henderson, Jeff Closs, Joshua Sampson, Charles J. Adam
  • Patent number: 10667908
    Abstract: Embodiments of the present disclosure are directed to prosthetic valves and methods of use thereof. In one implementation, a prosthetic valve may include an annular valve body and a plurality of ventricular anchoring legs configured to extend radially outward from the annular valve body. At least one ventricular anchoring leg may include a first concave portion situated between the valve body and a terminal end of the leg, and a second concave portion situated between the first concave portion and the terminal end of the leg. The first concave portion may face radially outward, while the second concave portion may face radially inward. At least one of the first concave portion and the second concave portion may be angularly aligned with a point of connection between the at least one leg and the valve body.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: June 2, 2020
    Assignee: CARDIOVALVE LTD.
    Inventors: Ilia Hariton, Boaz Harari
  • Patent number: 10667819
    Abstract: A delivery assembly includes a sleeve that fits snugly over a main endoscope over a distal end of the endoscope. A cylindrical carrier projects distally away from the sleeve and can carry one or more resilient tissue compression rings in a stretched configuration. A push ring is slidably disposed on the carrier, and an actuator is connected to the push ring. The actuator extends through the carrier, around a distal end of the carrier, and to the push ring to connect thereto such that when the actuator is pulled proximally, the push ring is urged distally on the carrier to push at least one compression ring off the carrier, at which point the compression ring is relaxed to assume a small configuration and clamp target tissue. The actuator may include a distal segment made of a flat ribbon.
    Type: Grant
    Filed: January 18, 2016
    Date of Patent: June 2, 2020
    Inventors: Wayne A. Noda, Brendan Cummings, Daniel Hyman
  • Patent number: 10667913
    Abstract: Tissue ingrowth on the distal loop portion of a constricting cord can dramatically improve the bond between the constricting cord and a cardiac valve annulus. But tissue ingrowth on the proximal portions of the constricting cord can interfere with the constricting action of the cord. This problem can be addressed by covering the proximal portions of the constricting cord with a material that resists tissue ingrowth, and waiting for tissue ingrowth to strengthen the bond between the distal loop portion of the constricting cord and the annulus. The reduced ingrowth on the proximal portions of the constricting cord make it easier to constrict the annulus when the constricting operation is eventually performed.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: June 2, 2020
    Assignee: Cardiac Implants LLC
    Inventors: David Alon, Nimrod Meller
  • Patent number: 10660758
    Abstract: An orthopedic implant has a removable handling cover coupled thereto which includes a thin-walled layer extending over a grasping portion of the outer surface. An outer container can sealingly house the orthopedic implant within a sterile environment and support the orthopedic implant in an orientation that presents the handling cover for grasping. A surgeon can manually grasp, handle and manipulate the implant into an implantation position, and remove the handling cover from the implant during implant surgery, and without the need to directly contact any surface of the orthopedic implant itself. Related methods of providing such an implant assembly and of reducing infection from contamination during implantation surgery are also disclosed.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: May 26, 2020
    Assignee: Biomet Manufacturing, LLC
    Inventors: Daniel B. Smith, Katie M. Schindler
  • Patent number: 10653522
    Abstract: The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular Compression Capable Annular Frames for a side delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: May 19, 2020
    Assignee: VDYNE, INC.
    Inventors: Robert Vidlund, Mark Christianson, Neelakantan Saikrishnan
  • Patent number: 10653523
    Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: May 19, 2020
    Assignee: 4C Medical Technologies, Inc.
    Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
  • Patent number: 10646333
    Abstract: A modular valve prosthesis includes an anchor stent and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the aorta and a proximal arm component extending from a proximal end of the tubular frame member and configured to be deployed in the sinuses of the aortic valve. The anchor stent further includes attachment members extending from an internal surface of the tubular frame member. The valve component includes a valve frame configured to be deployed within the tubular frame member of the anchor stent such that the valve frame engages with the attachment members of the tubular frame member and a prosthetic valve coupled to the valve frame.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: May 12, 2020
    Assignee: Medtronic, Inc.
    Inventor: Paul Rothstein
  • Patent number: 10646365
    Abstract: A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: May 12, 2020
    Assignee: Bolton Medical, Inc.
    Inventors: Humberto Berra, Samuel Arbefeuille, Fletcher Christian, Timothy Lostetter, Frank Borrego, Gerry Ouellette, Michael Moore
  • Patent number: 10639149
    Abstract: A prosthetic heart valve for replacing a native valve includes a stent extending between an inflow end and an outflow end, and a valve assembly disposed within the stent. The prosthetic heart valve may include a supra-annular feature configured to anchor and seal the prosthetic valve above the native valve annulus and a sub-annular feature configured to anchor and seal the prosthetic valve below the native valve annulus. Each of the sub-annular feature and the supra-annular feature may be a sealing ring or a strut that extends radially outward from the stent. The prosthetic heart valve may be implanted in the patient via a sutureless approach and provide anchoring in a variety of patient populations, including those with resected native valve leaflets.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: May 5, 2020
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Chad Joshua Green, Neelakantan Saikrishnan
  • Patent number: 10625059
    Abstract: An angioplasty apparatus and method, with a self-expanding stent, for facilitating accurate placement of the self-expanding stent for dilating a patient's blood lumen stenosis, the apparatus includes arcuate, low pressure, balloon segment(s) connected at a distal end of a deployment catheter assembly with axial gap(s) to facilitate continuous blood flow during a stenting procedure.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: April 21, 2020
    Inventor: Nadar A. Dakak
  • Patent number: 10617520
    Abstract: A method of implanting a prosthetic mitral heart valve includes advancing a guidewire through a femoral vein, an atrial septum, and a native mitral valve. A guide catheter is advanced over the guidewire and a delivery catheter is advanced through the guide catheter. A mitral valve assembly is disposed along a distal end of the delivery catheter. The mitral valve assembly includes a stent and a valve having three leaflets. The stent has a flared inlet end, an outlet end, and an intermediate portion with a plurality of prongs disposed along its outer surface. The mitral valve assembly is deployed with the flared inlet end positioned in a left atrium and the intermediate portion positioned between native mitral valve leaflets. The prongs penetrate surrounding tissue for preventing upward migration of the mitral valve assembly and the flared inlet end is shaped for preventing downward migration.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: April 14, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
  • Patent number: 10617519
    Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: April 14, 2020
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli, Lucian Lozonschi, Georg Lutter
  • Patent number: 10610355
    Abstract: The present invention relates to an anchoring device (1) designed for anchoring a prosthetic heart valve inside a heart, comprising an extraventricular part (2) designed to be positioned inside an atrium or an artery and a ventricular part (3) designed to be positioned inside a ventricle, wherein the ventricular part comprises a double wall composed of an outer wall (4) and an inner wall (5) spaced apart at the level where the prosthetic heart valve is intended to be inserted, and wherein the anchoring device further comprises a predefined V-shaped groove (8) formed between the extraventricular part (2) and the ventricular part (3). The present invention also relates to an anchoring system (11) for anchoring a prosthetic heart valve inside a heart, comprising said anchoring device (1), a prosthetic heart valve support (12) and a prosthetic heart valve (13) connected to the prosthetic heart valve support (12).
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: April 7, 2020
    Assignee: TRICARES (SAS)
    Inventors: Coralie Marchand, Cécile Riou