Combined With Surgical Tool Patents (Class 623/2.11)
  • Patent number: 11559397
    Abstract: In some examples, a delivery device includes a handle that includes a control member, an elongate body, a plurality of arms extending from a distal portion of the elongate body to a distal collar configured to releasably couple to an annuloplasty device. The plurality of arms is operatively coupled to the control member and configured to position the annuloplasty device at a target site in a patient. The delivery device further comprises a plurality of anchors configured to secure the annuloplasty device to tissue at the target site, each respective anchor of the plurality of anchors deployable from a respective arm of the plurality of arms.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: January 24, 2023
    Assignee: Medtronic Vascular, Inc.
    Inventors: Olivia Metcalf, Matthew E. Genovese, Caitlin Dorff, Emily Grimm, Fatemeh Fatemi Far, Karan Punga
  • Patent number: 11554015
    Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: January 17, 2023
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, James R. Yamada, Rodolfo Rodriguez, Da-Yu Chang, Steven M. Ford
  • Patent number: 11553893
    Abstract: Methods, systems, and coaptation measurement devices as described herein include an elongate sensor body at the end of a proximal connecting member, and a plurality of sensors in an array across a face of the sensor body, wherein each sensor of the plurality of sensors is configured to detect if a portion of a heart valve is in contact with the sensor.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: January 17, 2023
    Assignee: Children's Medical Center Corporation
    Inventors: David Hoganson, Peter E. Hammer
  • Patent number: 11554014
    Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: January 17, 2023
    Assignee: Medtentia International Ltd. Oy
    Inventor: Olli Keränen
  • Patent number: 11554010
    Abstract: Described is a prosthetic valve, comprising: an expandable stent including an inner lumen and having a first and a second end; and a spring attached to the first end of the expandable stent; wherein the expandable stent and the spring can expand radially to a desired diametric configuration in order to anchor the prosthetic valve at an implantation position in a body lumen. Related systems and methods.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: January 17, 2023
    Assignee: MEDTRONIC, INC.
    Inventors: Jason Quill, Cynthia T. Clague, Paul T. Rothstein
  • Patent number: 11547564
    Abstract: A valve repair device for repairing a native valve of a patient includes a pair of paddles and a pair of gripping members. The pair of paddles are movable between an open position and a closed position. Each paddle comprises a metal loop that is moveable from a compressed condition where each metal loop has a first width to an expanded condition where each loop has a second width that is greater than the first width. The pair of gripping members are configured to attach to the native valve of the patient.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: January 10, 2023
    Assignee: Edwards Lifesciences Corporation
    Inventors: Asher L. Metchik, Sergio Delgado, Alexander J. Siegel, Eric Robert Dixon, Lauren R. Freschauf, Matthew T. Winston, Gregory Scott Tyler, II
  • Patent number: 11540918
    Abstract: Prosthetic heart valves and methods of implantation thereof are disclosed herein. In embodiments, a prosthetic heart valve includes a self-expandable frame configured to support of valve member and comprising a plurality of interconnected strut members forming a mesh structure. An inflow end and outflow end portions of the mesh structure respectively define an inflow terminal end and an outflow terminal end of the frame. A portion of the frame tapers inwardly from the inflow terminal end to form a reduced diameter section. In implementations, the frame increases in diameter from the reduced diameter section to an intermediate section. In implementations, the valve member is secured to the frame at the inflow end portion. In implementations, the frame further comprises a plurality of retaining arms that extend from the outflow terminal end and are configured to engage with a valve retaining mechanism of a delivery apparatus.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: January 3, 2023
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Alon, Netanel Benichou, Oded Meiri
  • Patent number: 11534297
    Abstract: A delivery device for a stented heart valve includes a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: December 27, 2022
    Assignee: Medtronic 3F Therapeutics, Inc.
    Inventors: Andrzej M. Malewicz, David Elizondo, Matthew W. Weston
  • Patent number: 11534299
    Abstract: A delivery device includes an inner shaft, an outer sheath, a nosecone, and a tether component. The outer sheath is slidably disposed over the inner shaft. The nosecone is removably coupled to the inner shaft. The nosecone includes a delivery configuration for delivery to a treatment site, a radially compressed configuration in which a portion of the nosecone is configured to traverse through a heart wall, and a radially expanded configuration in which an outer surface of the nosecone contacts an outer surface of the heart wall. The tether component includes a first end coupled to the nosecone. The nosecone is configured to plug a piercing in the heart wall when in the radially expanded configuration.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: December 27, 2022
    Assignee: MEDTRONIC, INC.
    Inventor: Jason Quill
  • Patent number: 11534298
    Abstract: Prosthetic valves and methods of use of prosthetic valves may be provided. In one implementation, a prosthetic valve may include an annular outer frame, an inner frame, and a plurality of ventricular anchoring legs extending from the outer frame. The outer frame may be formed at least partially of struts intersecting at junctions. At least one ventricular anchoring leg may include a first curved leg portion on a first surface of the leg, and a second curved leg portion on a second, opposite surface of the leg. The outer frame may also include a strut extending between a downstream end of the outer frame and the junction from which the at least one ventricular anchoring leg extends.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: December 27, 2022
    Assignee: CARDIOVALVE LTD.
    Inventors: Ilia Hariton, Boaz Harari
  • Patent number: 11534296
    Abstract: A loading assembly for crimping and loading a prosthetic heart valve into a delivery device includes a loading base, a base funnel, and a compression member. The loading base has a support and a body extending from the support with a recess defined within the body. The recess is configured to receive a substantial portion of the annulus section of the heart valve in an at least partially collapsed condition. The base funnel is configured to be coupled to the loading base and to at least partially collapse the annulus section of the heart valve as it is inserted into the recess in the loading base. The compression member is configured to be coupled to the loading base with the heart valve inserted in the recess for further collapsing the heart valve and loading it into the delivery device.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: December 27, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Kristen T. Morin, Keith High, Ian Wright
  • Patent number: 11529232
    Abstract: The invention relates in general to the field of heart surgery. In the surgical field, instruments are used in order to examine the interior of living organisms and/or to use for operative interventions. These also include implants for the production of the functionality of a heart. The invention relates to such an implantable device and a method for eliminating regurgitation in the area of the heart. The implantable device is an annuloplasty ring with a large number of tissue anchors. An unfolded annuloplasty ring is positioned in the cavity of a body element in order to constrict a bodily opening. Using the minimally-invasive technique, each tissue anchor of the annuloplasty ring is intravascularly inserted in advance into a precise position on the edge of the mitral valve annulus.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: December 20, 2022
    Assignee: Immanuel Diakonie GmbH
    Inventor: Johannes Albes
  • Patent number: 11523902
    Abstract: Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly. The valve holding tube is releasably couplable to a proximal end portion of the catheter assembly and to a distal end portion of the handle assembly. The handle assembly includes a housing and a delivery rod. The delivery rod is configured to be actuated to move distally relative to the housing to move a prosthetic heart valve disposed within the valve holding tube out of the valve holding tube and distally within a lumen of the elongate sheath of the catheter assembly. The catheter assembly is configured to be actuated to move proximally relative to the housing such that the prosthetic valve is disposed outside of the lumen of the elongate sheath.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: December 13, 2022
    Assignee: Tendyne Holdings, Inc.
    Inventors: Craig A. Ekvall, Khoi Le, John F. Otte, Zachary J. Tegels, Robert M. Vidlund
  • Patent number: 11517435
    Abstract: A prosthetic cardiac valve assembly and method of implanting the same is disclosed. In certain disclosed embodiments, the prosthetic valve assembly is an annuloplasty ring with an attached artificial valve. The prosthetic valve assembly can be secured to native heart tissue by suturing or other suitable method of the annuloplasty ring to the native heart tissue. The prosthetic valve leaflets of the prosthetic valve can also be anchored to the native heart tissue to prevent prolapse. In certain embodiments, the prosthetic valve leaflets are anchored to the native papillary muscles. In still other embodiments, the prosthetic valve assembly contains exactly the number of prosthetic valve leaflets as are in the native valve that the prosthetic valve assembly is configured to replace. With the prosthetic valve assembly properly positioned, it will replace the function of the native valve.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: December 6, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventor: Harvey H. Chen
  • Patent number: 11504232
    Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: November 22, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Rafael Pintor, Mark Chau, Travis Zenyo Oba, August R. Yambao, Louis A. Campbell, Tammy Huntley, Qinggang Zeng, Carey L. Cristea, Faisal Kalam
  • Patent number: 11504064
    Abstract: The present disclosure relates to delivery devices and interventional devices configured to enable monitoring of pressure and other hemodynamic properties before, during, and/or after a cardiac procedure. A guide catheter includes a routing lumen or a routing groove for routing a sensor wire to a desired location during a cardiac procedure. A guide catheter includes one or more pressure sensors positioned to provide desired pressure measurements when the guide catheter is deploying an interventional device. An interventional device may also include one or more associated sensors for providing hemodynamic information before, during, and/or after deployment.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: November 22, 2022
    Assignee: EVALVE, INC.
    Inventors: Chad J. Abunassar, Brandon W. Chu, Patricia H. Ho, Koji J. Kizuka, Benjamin L. Lee, Tamer M. Mahmoud, Sean A. McNiven, Scott C. Mosher, Santosh V. Prabhu, Lauren G. Troxler, Dylan T. Van Hoven
  • Patent number: 11504228
    Abstract: A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: November 22, 2022
    Assignee: St. Jude Medical, LLC
    Inventors: Peter N. Braido, Paul E. Ashworth, Julia Ann Schraut
  • Patent number: 11484404
    Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
    Type: Grant
    Filed: June 4, 2022
    Date of Patent: November 1, 2022
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli, Lucian Lozonschi, Georg Lutter
  • Patent number: 11484331
    Abstract: Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: November 1, 2022
    Assignee: EVALVE, INC.
    Inventors: Eric A. Goldfarb, Troy L. Thornton, Alfred H. Raschdorf, Jaime E. Sarabia, John P. Madden, Ferolyn T. Powell, Brian B. Martin, Sylvia Erickson, Jan Komtebedde, Yen C. Liao
  • Patent number: 11484337
    Abstract: A surgical access device includes a cannula body and an anchor. The cannula body includes a housing, and an elongated portion extending distally from the housing. The elongated portion defines a longitudinal axis and defines a channel extending therethrough. The anchor is disposed in mechanical cooperation with the elongated portion of the cannula body and is longitudinally translatable relative to the elongated portion. The anchor defines an aperture and includes a ratchet mechanism configured to selectively lock a size of the aperture.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: November 1, 2022
    Inventors: Kevin Desjardin, Astley C. Lobo, Douglas M. Pattison, Christopher Tokarz
  • Patent number: 11484409
    Abstract: A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (DMR) or functional mitral valve regurgitation (FMR). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus. A tensioning mechanism connecting the ringless web to one or more of the anchors can be used to adjust a tension of the web such that web restrains the leaflet to prevent prolapse by restricting leaflet motion to the coaptation zone and/or promotes natural coaptation of the valve leaflets.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: November 1, 2022
    Assignee: NeoChord, Inc.
    Inventors: Giovanni Speziali, Dave Blaeser, John Zentgraf
  • Patent number: 11484370
    Abstract: Methods of delivering a prosthetic aortic heart valve are disclosed.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: November 1, 2022
    Assignee: HBX, Inc.
    Inventor: Paul A. Spence
  • Patent number: 11464639
    Abstract: Methods for generating aortic heart valve leaflets are disclosed wherein the aortic sinus surfaces (the inner surfaces of the sinuses of Valsalva) are used as a template to generate geometric representations of replacement aortic heart valve leaflets. As such, sinus-matched replacement leaflets can be sized and shaped according to the patient-specific geometry of the aortic root. Patient-specific aortic valve assemblies based on aortic root and sinus geometry are also described. Methods for estimating the coaptation area of a sinus-matched valve and assessing whether the valve is functionally competent for implantation are described.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: October 11, 2022
    Assignees: Oregon Health & Science University, Iowa State University Research Foundation
    Inventors: Gary Michael Silberbach, Ming-Chen Hsu, Xiao-Yue Han
  • Patent number: 11464946
    Abstract: Embodiments hereof relate to methods of delivering a valve prosthesis to an annulus of a native valve of a heart, the native valve having chordae tendineae. A chordae management catheter is positioned within a ventricle of the heart, the chordae management catheter having a displacement component at a distal end thereof. The displacement component has an annular shape and defines a central lumen therethrough. The displacement component is radially expanded to push chordae tendineae within the ventricle radially outward. A valve delivery system is introduced into the ventricle of the heart via a ventricular wall of the heart. The valve delivery system has the valve prosthesis at a distal portion thereof. The valve delivery system is advanced through the central lumen of the radially expanded displacement component towards the annulus of the native valve of the heart. The valve prosthesis is deployed into apposition with the annulus of the native valve.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: October 11, 2022
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Paul Devereux, Paraic Frisby, Frank White, Tomas Kitt, Marc Anderson, Grainne Carroll, Ciaran McGuinness, Tim Jones, Patrick Griffin
  • Patent number: 11464634
    Abstract: The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: October 11, 2022
    Assignee: Polares Medical Inc.
    Inventors: Alexander K. Khairkhahan, Jacques Essinger, Alan Klenk
  • Patent number: 11458015
    Abstract: Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: October 4, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yidong M. Zhu, Erik Bulman, Baigui Bian, Sam Sok, Pu Zhou
  • Patent number: 11452602
    Abstract: A method and device for anchoring a prosthetic heart valve or annuloplasty ring to a valve annulus in a heart and a method of implanting same is disclosed. The device can include a prosthetic valve or annuloplasty ring with one or more anchors configured to be threaded or otherwise passed underneath a native leaflet and/or subvalvular tissue to secure the device at the native annulus.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: September 27, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventor: Brian S. Conklin
  • Patent number: 11452600
    Abstract: A system for delivering a collapsible and re-expandable prosthetic heart valve into a patient includes a valve support structure around which the valve is disposed in a collapsed condition. A sheath structure surrounds the collapsed valve, but can be moved relative to the valve to uncover it for expansion at the desired implant site in the patient. The sheath structure may be variously mounted and moved to deploy the valve in various ways. For example, the sheath structure may include multiple parts, each of which can be moved separately to separately deploy various parts of the valve. The apparatus may have other aspects, such as the ability to reverse deployment of the valve, the ability to pass other instrumentation through the valve delivery apparatus, the ability to be smoothly withdrawn from the patient after deployment of the valve, etc.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: September 27, 2022
    Assignee: St. Jude Medical, LLC
    Inventor: Yousef F. Alkhatib
  • Patent number: 11446144
    Abstract: A valve prosthesis, implantation device, and methods for use are provided. The devices described herein may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device can utilize movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: September 20, 2022
    Assignee: JC Medical, Inc.
    Inventor: Ji Zhang
  • Patent number: 11439525
    Abstract: The present invention relates to a device (3) intended to be attached to or interconnected with a medical implant (1), and intended to be attached to or interconnected with a catheter (5), the catheter (5) being intended for implanting the implant (1). The invention further relates to a catheter (5) suited for receiving at least one such device (3) and to a method.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: September 13, 2022
    Assignee: Venus Medtech (Hangzhou) Inc.
    Inventors: Wolfgang Goetz, Hou-Sen Lim
  • Patent number: 11432884
    Abstract: Methods of delivering a prosthetic aortic heart valve are disclosed.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: September 6, 2022
    Assignee: HBX, Inc.
    Inventor: Paul A. Spence
  • Patent number: 11432926
    Abstract: A percutaneous device including a temporary valve attached to a sheath, the sheath having an inverting section for delivery and removal thereof from a blood vessel. The sheath is inverted for delivery, housing the valve between inverted layers thereof. To deploy said valve, the sheath is everted to position the temporary valve on an outer surface thereof. The temporary valve and sheath are reversibly movable between inverted and deployed configurations. Upon eversion, the temporary valve assumes a radially expanded canopy shape having an outer diameter selected to contact the vessel wall and allow blood flow in only one direction. The temporary valve may be removed by releasing one end of the valve from the sheath, flattening the temporary valve along the longitudinal axis of the sheath. Also provided is a temporary valve system comprising a dilator for inverting and everting the sheath, said dilator being removably connected to the sheath.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: September 6, 2022
    Assignee: Valve Medical Ltd.
    Inventors: Yoram Richter, Ety Weisz, Mark Kreizer
  • Patent number: 11419716
    Abstract: A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end. The sealing structure may have an outer edge remote from the inner edge. The sealing structure may have a collapsed condition with the outer edge disposed adjacent the outer surface of the cuff and an expanded condition with the outer edge spaced apart from the outer surface of the cuff.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: August 23, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Kent J. Smith, Andrea L. McCarthy, Mina S. Fahim
  • Patent number: 11419720
    Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: August 23, 2022
    Assignees: Neovasc Tiara Inc., Edwards Lifesciences CardiAQ LLC
    Inventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
  • Patent number: 11419743
    Abstract: A system for delivering an implantable medical device includes an outer sheath drive assembly and an actuation shaft drive assembly. The outer sheath drive assembly is configured to cause an outer sheath to translate relative to a handle, and includes an outer sheath drive motor. The actuation shaft drive assembly is configured to cause an actuation shaft to translate relative to the handle, and includes an actuation shaft drive motor. The outer sheath drive motor and/or the actuation shaft drive motor may be removed from the system, and the outer sheath drive assembly and/or the actuation shaft drive assembly may instead be manually driven.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: August 23, 2022
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Kevin Robert Poppe, Daniel J. Foster, Bradley S. Swehla, Christopher Jay Scheff, Eric Gagner
  • Patent number: 11413086
    Abstract: Methods, systems and devices for applying energy to tissue, and more particularly relates to a system for ablating or modifying structures in a body with systems and methods that generate a flow of vapor at a controlled flow rate for applying energy to the body structure.
    Type: Grant
    Filed: October 27, 2021
    Date of Patent: August 16, 2022
    Assignee: Tsunami MedTech, LLC
    Inventors: Michael Hoey, John H. Shadduck
  • Patent number: 11399933
    Abstract: The present application relates to a cardiac valve prosthesis and a stent thereof. The stent comprises an inflow channel, an outflow channel, and a transitional area between the inflow channel and the outflow channel along an axial direction; the outflow channel comprises a cyclic structure and at least two convex structures extending along the axial direction; the at least two convex structures are respectively connected to the end of the cyclic structure distant from the transitional area; a restricted vacant area is formed between adjacent convex structures. The cardiac valve prosthesis and the stent thereof are not only suitable for multiple types of valve replacement, risks of injuries and operation costs are reduced for patients, and the influence of the stent to cardiac functions is minimized.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: August 2, 2022
    Assignee: SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
    Inventors: Chunxia Zhao, Ming Yang, Guoming Chen, Yu Li
  • Patent number: 11399938
    Abstract: A delivery device for percutaneously delivering a stented prosthetic heart valve includes a capsule assembly, a handle, and an outer stability shaft. The capsule assembly includes a capsule and a proximal shaft coupled to the capsule. The capsule includes an expanded configuration wherein the capsule has a first outer diameter, and a collapsed configuration wherein the capsule has a second outer diameter smaller than the first outer diameter. The outer stability shaft defines a lumen and is coupled to the handle and configured to receive the proximal shaft within the lumen of the outer stability shaft. The outer stability shaft has an inner diameter, wherein the first outer diameter of the capsule is greater than the inner diameter of the outer stability shaft and the second outer diameter of the capsule is smaller than the inner diameter of the outer stability shaft.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: August 2, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: Joel Racchini, Jeffrey Sandstrom
  • Patent number: 11399935
    Abstract: Transcatheter guidewire delivery systems, catheter assemblies and associated methods for percutaneous guidewire delivery across heart valves are disclosed herein. A catheter assembly configured in accordance herewith includes an elongated tubular component and an alignment assembly at a distal portion of the tubular component and which is adapted to be located at a target location adjacent a heart valve of a patient. In one embodiment, the alignment assembly deploys to a shape set loop configuration with a side port in an open configuration positioned to allow advancement of a guidewire to exit the catheter in an aligned path with a leaflet coaptation region of the heart valve. In another embodiment, the alignment assembly has a plurality of spaced apart side ports that a guidewire may advance therethrough and toward the heart valve. In some embodiments, a wire guide is used to align the guidewire with a selected side port.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: August 2, 2022
    Assignee: Medtronic Vascular, Inc.
    Inventors: Simon Kiersey, Tomas Kelly
  • Patent number: 11395735
    Abstract: A valve stent and a valve prosthesis. The valve stent is in the shape of a mesh tube, and has a compressed state and an expanded state. The valve stent includes an inflow tract structure, a transition tract structure, an outflow tract structure, and a barb structure. The transition tract structure has a fifth end portion, a sixth end portion, and a first middle section. In the expanded state, the diameters of the radial sections of the fifth end portion and the sixth end portion are greater than the diameter of the radial section of the first middle section of the transition tract structure. The outflow tract structure has a seventh end portion and an eighth end portion. The seventh end portion of the outflow tract structure is fixedly connected to the sixth end portion of the transition tract structure, and the eighth end portion is a free end.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: July 26, 2022
    Assignee: SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
    Inventors: Chunxia Zhao, Ming Yang, Guoming Chen, Yu Li
  • Patent number: 11389293
    Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: July 19, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: Mark Torrianni, Kshitija Garde, Eric Richardson
  • Patent number: 11389294
    Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore, One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: July 19, 2022
    Assignee: Neovasc Tiara Inc.
    Inventors: Colin A. Nyuli, Randy Matthew Lane
  • Patent number: 11389297
    Abstract: An implantable prosthetic spacer device can include an inflatable spacer having a plurality of inflatable members and a frame, the frame comprising one or more anchors and one or more clasps. The inflatable spacer can be configured to be disposed between native leaflets of a heart. The implantable prosthetic spacer can be disposed in a symmetrical or an asymmetrical configuration. The inflatable spacers can be inflatable between an uninflated and an inflated configuration.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: July 19, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Michael D. Franklin, Matthew T. Winston, Lauren R. Freschauf, Eric Robert Dixon, Yoon Hee Kwon
  • Patent number: 11383075
    Abstract: Miniature axial flow pumps are implanted inside the heart or major arteries to provide hemodynamic support. These pumps commonly utilize tubular blood conduit tubes to transport blood across the aortic valve. The valve leaflets themselves are very thin and flexible, and will seal against the conduit if it is centered within the valve orifice. The present invention provides a conduit support device that retains the conduit centered within the annulus of the natural heart valve. A leaflet valve stent may be combined with a conduit support device comprised of a ring supported by posts attached to the valve stent ring. A blood pump may be attached to the center of a transvalvular support stent, for optimal fixation of the pump with relation to a trileaflet or bi-leaflet tissue or polymer valve.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: July 12, 2022
    Inventor: Robert Jarvik
  • Patent number: 11382780
    Abstract: A system and method for loading a self-expandable prosthetic device into a delivery device. The system includes a compression member that has a chamber with a tapered inner surface, a support member, a splay member and a constriction member. The compression member and the constriction member can be releasably attached to each other directly or via a spacer element, in two different positions relative to each other. The first position offers an optimal configuration for releasable attachment of the prosthetic device to the delivery device and the second position offers an optimal configuration for reducing the diameter of the delivery device. The risk of damaging the delivery device and to the prosthetic device during the loading procedure is thereby reduced.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: July 12, 2022
    Assignee: BIOTRONIK AG
    Inventors: Maximilian Mayer, Christian Erbe, Markus Hepke
  • Patent number: 11382737
    Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
    Type: Grant
    Filed: January 13, 2022
    Date of Patent: July 12, 2022
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli, Lucian Lozonschi, Georg Lutter
  • Patent number: 11382749
    Abstract: Systems and methods for percutaneous, transcatheter heart valve repair are disclosed. A system may include a catheter, an adjustable ring, and a stabilizer. The adjustable ring may include a body member that is transitionable from an insertion geometry to an operable geometry. The insertion geometry may be configured to allow percutaneous passage of the ring into the heart. The operable geometry may have an expanded state to conform to an annulus of a target valve and a contracted state to reduce a diameter of the annulus. The adjustable ring may also include a plurality of anchors deployable in the operable geometry to engage the annulus. The stabilizer may include a plurality of prongs configured to engage the ring in the operable geometry within the heart to enable percutaneous manipulation of the ring to orient and position the ring in intimate contact with the annulus.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: July 12, 2022
    Assignee: VALCARE, INC.
    Inventors: Nadav Yellin, Samuel M. Shaolian, Jeffrey P. Dumontelle
  • Patent number: 11376125
    Abstract: A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: July 5, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian S. Conklin, Michael C. Murad
  • Patent number: 11376120
    Abstract: A transcatheter valve prosthesis is disclosed that has a compressed, delivery configuration and an expanded configuration for deployment within a native heart valve. The valve prosthesis includes a self-expanding frame and a prosthetic valve component. The self-expanding frame includes a valve receiving portion defining an opening therethrough and first and second anchors at opposing ends of the valve receiving portion. The valve receiving portion is substantially planar and the first and second anchors are oriented substantially perpendicular to the valve receiving portion when the valve prosthesis is in the expanded configuration. The prosthetic valve component is disposed within the opening of the valve receiving portion and secured thereto.
    Type: Grant
    Filed: October 19, 2020
    Date of Patent: July 5, 2022
    Assignee: MEDTRONIC VASCULAR GALWAY
    Inventor: Declan Costello
  • Patent number: 11369470
    Abstract: A loading tool for loading a collapsible prosthetic heart valve into a delivery device may include a body extending in a longitudinal direction between a proximal end and a distal end, an extension on the distal end of the body, and a slot extending through the extension from a free end of the extension toward the distal end of the body. The body may include a lumen extending between the proximal end and the distal end, the body lumen having a first diameter. The extension may have a lumen coaxial with the body lumen, the extension lumen having a second diameter less than the first diameter so as to define a shelf surface between the proximal end of the body and the free end of the extension.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: June 28, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Mark Krans, Theodore Paul Dale, Andrea N. Para, Mathias Charles Glimsdale, Thomas M. Benson, Peter N. Braido