Combined With Surgical Tool Patents (Class 623/2.11)
  • Patent number: 11141275
    Abstract: A mitral valve leaflet repair system may include a delivery catheter having at least one lumen extending proximally from a distal end of the delivery catheter, a plurality of anchor elements disposed within the at least one lumen, each of the plurality of anchor elements being configured to extend through one layer of mitral valve leaflet tissue, and a securing element configured to secure at least two of the plurality of anchor elements together on one side of the mitral valve leaflet tissue. The at least one lumen may include a suction lumen configured to grasp a mitral valve leaflet prior to extending the plurality of anchor elements through one layer of mitral valve leaflet tissue.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: October 12, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Omar Jarral, Patricia McAfee, Aiden Flanagan, Tim O'Connor, Jan Weber
  • Patent number: 11141272
    Abstract: A method of deploying a blood-flow controlling device is described for treating a native mitral or tricuspid valve. The blood-flow controlling device includes a blood-flow blocking portion that is slidable over an elongate body portion. The blood-flow blocking portion is preferably an elongate structure fillable with blood having a portion adapted for placement between leaflets of the native valve. An anchor is located on a distal end of the elongate body portion for engagement with heart tissue adjacent a heart apex. An anchor delivery catheter is advanced through the native valve and into an adjacent ventricle. The anchor is then expelled from the anchor delivery catheter into ventricular tissue. The blood-flow blocking portion is then slid along the elongate body portion and positioned between the native leaflets. A locking catheter is then slid along the elongate body portion for locking the blood-flow blocking portion to the elongate body portion.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: October 12, 2021
    Inventors: Jan Otto Solem, David Alon
  • Patent number: 11141265
    Abstract: A method for delivering a heart valve prosthesis to a native valve annulus comprises expanding an expandable frame at the native valve annulus and positioning a replacement heart valve within the expandable frame. The expandable frame preferably includes a first anchoring portion that is positioned on a first side of the native valve annulus and a second anchoring portion that is positioned on a second side of the native valve annulus. The first anchoring portion engages tissue on the first side of the native valve annulus and the second anchoring portion engages tissue on the second side of the native valve annulus for securing the expandable frame to the native valve annulus. The replacement heart valve comprises a plurality of leaflets for replacing the function of the native valve.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: October 12, 2021
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventor: Arshad Quadri
  • Patent number: 11141300
    Abstract: An implant delivery system is described, having a distal tip and outer sheath that remain in a fixed position during implant delivery. A pusher mechanism within the sheath pushes an implant out of a gap between a distal end of the sheath and the distal tip.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: October 12, 2021
    Assignee: Terumo Corporation
    Inventors: Cang Lam, Shirley Vong, Greg Kelley
  • Patent number: 11141270
    Abstract: A prosthetic heart valve for replacing a defective aortic valve includes a self-expandable annular frame made of shape-memory material. A one-way valve structure is disposed within an interior of the frame. The frame includes a plurality of posts projecting axially from an outflow end portion of the frame, wherein each of the posts includes an axial post portion and a terminal post portion. The terminal post portions have greater circumferential dimensions than the axial post portions. The terminal post portions are preferably formed with concave inner surfaces and convex outer surfaces for conforming to the shape of a delivery catheter. Each of the posts is shaped for placement within a corresponding recess along a distal end portion of the delivery catheter for ensuring that the prosthetic heart valve remains coupled to the delivery catheter while the prosthetic heart valve is expanded within the defective aortic valve.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: October 12, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Alon, Netanel Benichou, Oded Meiri
  • Patent number: 11141273
    Abstract: An occluder device for occluding a gap between a medical device and adjacent body tissue includes a conformable body having a hollow interior, a leading end and a trailing end; and a port disposed at the trailing end of the body and in fluid communication with the interior of the body.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: October 12, 2021
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Gregory James Dakin, Peter Nicholas Braido
  • Patent number: 11135062
    Abstract: Methods, systems, and apparatuses for treating a heart are provided. Methods can include obtaining and using an implant. One or more catheters can be used to properly position and attach the implant in a desired location in a chamber of the heart, for example, on a ventricular wall of the left ventricle between one or more papillary muscles of the left ventricle and the annulus. Then a distance along the implant or a region of the heart, for example, between the papillary muscle and the annulus, can be reduced by contracting the implant along its longitudinal axis by applying tension to a contraction member of the implant. Other embodiments are described.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: October 5, 2021
    Assignee: Valtech Cardio Ltd.
    Inventors: Yaron Keidar, Nima V. Nia, Stanton J. Rowe, Hengchu Cao, Tal Reich
  • Patent number: 11135053
    Abstract: The present application provides an implantation method of an artificial heart valve. The implantation method can include forming an incision in the left chest to expose the ventricle; advancing a guide wire kept away from chordae tendineaes through the atrium into the ventricle; advancing a guide wire catcher into the ventricle from the incision to pull out the distal end of the guide wire from the ventricle; and advancing the artificial heart valve into the ventricle from the distal end of the guide wire with a valve deliverer, and placing the artificial heart valve at a primary valve between the ventricle and the atrium along the guide wire. The artificial heart valve may avoid the chordae tendineaes in the heart system through the guide wire track during implantation.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: October 5, 2021
    Assignee: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
    Inventors: Zhiwei Wang, Jianzhou Guo, Wenbin Chen, Wei Jiang, Huixiong Xie, Xiangdong Liu, Bin Yao
  • Patent number: 11135055
    Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: October 5, 2021
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli, Lucian Lozonschi, Georg Lutter
  • Patent number: 11129716
    Abstract: A heart valve annulus repair device having a tissue engaging member and a plurality of anchors. The tissue engaging member includes a loop of wire. Each of the anchors has a pointy front end and a back end and a slot that runs in a front-to-back direction. The anchors are distributed about the loop of wire with the front ends of the plurality of anchors facing the heart valve annulus and with the loop of wire passing through the slots. The device further includes means for implanting the anchors into the heart valve annulus tissue so that the tissue engaging member becomes affixed to the heart valve annulus.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: September 28, 2021
    Assignee: Cardiac Implants, LLC
    Inventor: David Alon
  • Patent number: 11123184
    Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: September 21, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tamir S. Levi, Son V. Nguyen, Netanel Benichou, David Maimon, Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Larisa Dadonkina, Ron Sharoni, Elena Sherman
  • Patent number: 11123181
    Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: September 21, 2021
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli, Lucian Lozonschi, Georg Lutter
  • Patent number: 11123189
    Abstract: The present disclosure relates to heart valve prostheses, delivery devices, actuation handles, and other improved devices and methods that facilitate delivery of a heart valve prosthesis to a defective native valve structure in a patient, such as the aortic valve.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: September 21, 2021
    Assignee: JC MEDICAL, INC.
    Inventors: Ji Zhang, Brandon G. Walsh, Cheng Yong Yang, Jinhua Zhu
  • Patent number: 11116636
    Abstract: A prosthetic system for heart valve replacement comprises an annular support structure within which a valved prosthetic body can be expanded until it meets opposition. The annular support is provided in ring segments having terminal connectors for forming, in the condition of use of the prosthetic system, a stable and durable annular structural continuity capable of withstanding the opposition exerted by the valved prosthetic body. The prosthetic system is deployed using guide wires within a cardiac chamber guided through an introducer catheter having through lumens, within which at least two first guide catheters are positioned. These guide catheters have respective deflected or deflectable distal ends adapted to emerge from the distal end of the introducer catheter to convey and direct the distal ends of respective guide wires, placed within the guide catheters, towards a capture member of a capture system which is provided within the introducer catheter.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: September 14, 2021
    Assignee: INNOVHEART S.r.l.
    Inventors: Giovanni Righini, Sarah Zanon
  • Patent number: 11109966
    Abstract: Embodiments hereof relate to centering devices for use with a valve delivery system and methods of delivering a valve prosthesis within a vasculature. A valve centering catheter is configured for use with a valve delivery system. The valve centering catheter includes a circumferential centering device at a distal portion thereof, and the circumferential centering device defines a central opening there-through when in an expanded configuration. The circumferential centering device is annular or has a C-shaped cross-section. The valve delivery system is tracked through the vasculature until the valve prosthesis is positioned through the central opening of the expanded circumferential centering device. The valve centering catheter may alternatively include a longitudinal centering device which acts as a marker for depth control during delivery of a valve delivery system, which may include an integral circumferential centering device.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: September 7, 2021
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventor: Frank White
  • Patent number: 11096780
    Abstract: A paravalvular leak resistant prosthetic heart valve system including a stent frame, a valve structure and a sealing mechanism. The stent frame has a surface. The valve structure is associated with the stent frame. The sealing mechanism at least partially extends over the surface of the stent frame. The sealing mechanism includes at least one semi-permeable membrane and an osmotic gradient driving material.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: August 24, 2021
    Assignee: Medtronic, Inc.
    Inventors: Wei Wang, Joshua Dudney, Kshitija P. Garde, Laura McKinley, Benjamin Wong
  • Patent number: 11096784
    Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. The clasps each have a fixed arm and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the moveable arms to the fixed arm.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: August 24, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Eric Robert Dixon, Hengchu Cao, Douglas Thomas Dominick, Lauren R. Freschauf
  • Patent number: 11076957
    Abstract: An implant for improving coaptation of an atrioventricular valve in which the atrioventricular valve has a first native leaflet, a second native leaflet and an annulus includes a support structure configured to be arranged on and fixed to the annulus or to at least one of the first and second native first leaflets. The implant also includes flexible retention structure mounted to the support structure so as to prevent prolapse of the at least one of the first and second native leaflets. A method for improving coaptation of such an atrioventricular valve is also disclosed.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: August 3, 2021
    Assignee: AVVIE GMBH
    Inventor: Werner Mohl
  • Patent number: 11076955
    Abstract: A prosthetic heart valve can include a support stent, a valve assembly, and a connection structure. The support stent can have an inlet end portion and an outlet end portion, and can be configured to be radially expandable from a crimped configuration to an expanded configuration. The valve assembly can have an inlet, an outlet, and a plurality of leaflets. The connection structure supports the valve assembly in the support stent such that the inlet of the valve assembly is spaced radially inwardly of the support stent and forms an annular space between an inner surface of the support stent and the valve assembly at the inlet of the valve assembly when the support stent is in the expanded configuration. The annular space can have a width in a radial direction between 0.5 cm and 3 cm.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: August 3, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventor: Stanton J. Rowe
  • Patent number: 11071624
    Abstract: An artificial heart valve stent including: a tubular stent body having an inflow side end and an outflow side end, the inflow side end and the outflow side end being opposite to each other; an inflow side skirt surrounding the external wall of the stent body; and an outflow side skirt surrounding the external wall of the stent body. In a spread state, free ends of the inflow side skirt and the outflow side skirt extend toward the inflow side end; and the inflow side skirt cooperates with the outflow side skirt to clamp heart valve tissues. The artificial heart valve stent can be steadily arranged on heart valve tissues, prolong the service life of an artificial heart valve and reduce the risk of another artificial heart valve replacement for the patient.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: July 27, 2021
    Assignee: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
    Inventors: Jian Zhuang, Huiming Guo, Huanlei Huang, Zhiwei Wang, Xiangdong Liu, Mingjuan Fu, Wei Jiang, Deyuan Zhang
  • Patent number: 11071628
    Abstract: A linking member extends from a first linking site of a longitudinal member to a second linking site of the longitudinal member. An anchor driver is configured to anchor portions of the longitudinal member to tissue using tissue anchors. A distal portion is anchorable to a first tissue location while the first linking site is within a catheter. While the distal portion is anchored to the first location, and the second linking site is within the catheter, a second portion is advanceable distally out of the catheter and is anchorable to a second tissue location. While the second portion is anchored to the second location, the second linking site and a third portion are advanceable distally out of the catheter. After the second linking site has been advanced out of the catheter, the third portion is anchorable to a third tissue location. Other embodiments are also described.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: July 27, 2021
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Tai Reich, Yaron Herman, Ehud Iflah, Haim Brauon, Meir Kutzik, Meni Iamberger
  • Patent number: 11058539
    Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the paddle and a moveable arm. The moveable arm has a barbed portion, a first eyelet, and a second eyelet. The hinge portion connects the fixed arm to the moveable arm. A first intermediate suture loop is attached to the first eyelet and a second intermediate suture loop is attached to the second eyelet. At least one actuation suture is attached to the first and second intermediate suture loops.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: July 13, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Eric Robert Dixon, Jensen Chen, Guillermo W. Moratorio, Hengchu Cao, Douglas Thomas Dominick, Sergio Delgado
  • Patent number: 11058537
    Abstract: Described embodiments include apparatus (20) that includes an assembly of tubes (34), each one of the tubes being shaped to define a tube lumen (62). The apparatus further includes a plurality of tissue anchors (60), each one of the tissue anchors being disposed within a respective one of the tube lumens, an expandable annular structure (36), including a plurality of teeth (40), coupled to the assembly of tubes, and a plurality of control wires (38) coupled to the annular structure, configured to position the tubes for deployment of the tissue anchors from the tube lumens, by manipulating the annular structure. Other embodiments are also described.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: July 13, 2021
    Assignee: VALFIX MEDICAL LTD.
    Inventors: Eli Bar, Elad Yaacoby
  • Patent number: 11051935
    Abstract: Systems and methods for medical interventional procedures, including approaches to valve implant. In one aspect, the methods and systems involve a modular approach to treatment.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: July 6, 2021
    Assignee: Caisson Interventional, LLC
    Inventors: Cyril J. Schweich, Jr., Todd J. Mortier
  • Patent number: 11039923
    Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. The disclosure also provides improved techniques for cardiac pacing.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: June 22, 2021
    Assignee: Transmural Systems LLC
    Inventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee
  • Patent number: 11026675
    Abstract: A device for cardiac surgery is disclosed, having a) a plurality of pairs of suture guides spaced about the frame; b) a plurality of suture tubes, with one suture tube corresponding to each pair of suture guides; c) a plurality of snares, each corresponding to and passed through one of the plurality of suture tubes so that a handle at one end of the snare protrudes from a proximal end of the corresponding suture tube and a snare loop at another end of the snare protrudes through a distal end of the corresponding suture tube, and wherein the snare loop further protrudes through one of the suture guides in the corresponding pair of suture guides; and d) a plurality of sutures, each corresponding to one of the pairs of suture guides and coupled to the suture guide in the corresponding pair of suture guides which does not have the snare loop passing through it.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: June 8, 2021
    Assignee: LSI SOLUTIONS, INC.
    Inventor: Jude S. Sauer
  • Patent number: 11026787
    Abstract: A holder for a prosthetic heart valve may include a hub having an outer surface extending about a longitudinal axis, a commissure support extending downward from the hub, and a plurality of legs extending outward from the hub in radial directions, each leg having a foot extending in a longitudinal direction. Each foot may have two channels on its outer surface, each channel extending from a closed end at a spaced distance from the bottom of the foot to an open end at the bottom of the foot, and two suture holes each spaced apart from the bottom of the foot and extending between the inner surface and the outer surface of the foot.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: June 8, 2021
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Richard Kaleta
  • Patent number: 11026791
    Abstract: A system for treating valvular regurgitation in a heart valve includes a flexible canopy and an elongated tether including an elastic portion and an inelastic portion. When the system is in a deployed configuration, a proximal end of the flexible canopy is coupled to an annulus of the heart valve and a distal end of the elongated tether is coupled to a ventricle. The flexible canopy is configured to overlay a first native leaflet of the heart valve, and tension on the elongated tether is applied and/or adjusted to prevent the first leaflet from prolapsing, to maximize coaptation of the flexible canopy with a second native leaflet of the heart valve, and to minimize regurgitation of the heart valve.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: June 8, 2021
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Matthew Genovese, Jeffrey Sandstrom, Russell Pribanic, Thomas Mcpeak, Vania Lee, Dermot O'Brien, James Calvin Allan
  • Patent number: 11026784
    Abstract: A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: June 8, 2021
    Assignee: HLT, Inc.
    Inventors: Gary A. Thill, Robert Foster Wilson, John P. Gainor, Christopher M. Banick
  • Patent number: 11020225
    Abstract: Disclosed is a medical system for short time replacement and repair of a native valve, which comprises an artificial valve (502); and a device for collecting and arranging chordae and/or leaflets to hold and/or stabilize the artificial valve in a desired position, the device comprising: a unit for grasping a plurality of chordae and/or leaflets. The system and/or device allows for fast and easy replacement of a native valve, fast and easy positioning of a temporary artificial valve, and more time for medical personnel to make decisions, prepare and/or perform surgery/medical intervention.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: June 1, 2021
    Assignee: Medtentia International Ltd Oy
    Inventors: Olli Keränen, Mark Pugh, Ger O'Carroll, Adrian Moran
  • Patent number: 10993805
    Abstract: A method of placing an implant including a stent at a native heart valve site includes orienting an expandable body of the stent such that a first open end of the stent is upstream a second open end of the stent relative to a direction of blood flow through a native heart valve. The native heart valve includes native leaflets and an annulus. The method also includes radially expanding a plurality of positioning arches positioned around an outer perimeter of the expandable body. The method additionally includes inserting the plurality of positioning arches respectively within a plurality of pockets defined by leaflets of the native heart valve and a heart structure from which the native leaflets extend. The method further includes radially expanding the first open end of the stent into a position upstream of the annulus and out of contact with nerve bundles.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: May 4, 2021
    Assignee: JenaValve Technology, Inc.
    Inventors: Helmut Straubinger, Johannes Jung, Michael J. Girard, Arnulf Mayer
  • Patent number: 10987219
    Abstract: An embodiment includes a chordal replacement system comprising: a pledget coupled to a first suture length and at least one of a first needle and a first ferrule; a second suture length coupled to the pledget and at least a second needle; and a third suture length coupled to the pledget and at least a third needle; wherein the second and third suture lengths are not monolithic with each other and do not constitute a single suture. Other embodiments are described herein.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: April 27, 2021
    Assignee: ON-X LIFE TECHNOLOGIES, INC
    Inventors: Ryan Medema, Jeffrey Nelson, Anthony Lioi, Clyde Baker, Fletcher D. Southard, Mark E. Seeley
  • Patent number: 10980632
    Abstract: A prosthetic heart valve (1) for implantation at the mitral annulus of a heart, the prosthetic heart valve comprising: a support framework (10) reversibly transformable between a collapsed configuration and an expanded configuration; and one or more leaflets connected to the framework; wherein, in the expanded configuration: the support framework defines a fluid pathway through the prosthetic heart valve, the fluid pathway having a portion with a D-shaped cross section for engaging the mitral annulus; and the one or more leaflets allow fluid to pass through the fluid pathway in a first direction but prevent fluid from flowing in the opposite direction.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: April 20, 2021
    Assignee: Fondazione RIMED
    Inventors: Gaetano Burriesci, Selim Bozkurt, Benyamin Rahmani, Michael J. Mullen
  • Patent number: 10973633
    Abstract: This invention discloses a valved stent for implantation at a dysfunctional or diseased atrioventricular valvular annulus. The valved stent is expandable from a collapsed shape to an expanded shape for minimally invasive delivery and has a low profile at the atrial or superior aspect to achieve improved hemodynamics and offers the capability to fabricate replacement valves having large diameters, The invention also includes a delivery apparatus uniquely designed for implantation of the valved stent and offering the potential for controlled and precise placement of the valved stent at the atrioventricular annulus. The invention also includes methods for use of the above devices and for treating diseased atrioventricular valves.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: April 13, 2021
    Assignee: NAVIGATE CARDIAC STRUCTURES, INC.
    Inventors: Rodolfo C. Quijano, Ryan Bertwell
  • Patent number: 10973635
    Abstract: Devices, systems, and methods for crimping a medical device are disclosed. More specifically, the present disclosure relates to devices, systems, and methods for reducing the diameter of a collapsible heart valve prosthesis to be loaded onto a delivery device. The devices, systems, and methods using at least one funnel to crimp the heart valve prosthesis and load it onto the delivery system.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: April 13, 2021
    Assignee: MEDTRONIC VASCULAR GALWAY
    Inventors: Niall Duffy, Marian Lally, Philip Haarstad, Frank Harewood, Igor Kovalsky, Jason Quill, Daniel Gelfman, Ana Menk, Darren Janzig, Shyam Gokaldas, Kenneth Dale Warnock, Jr.
  • Patent number: 10973639
    Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a base assembly, a pair of paddles, and a pair of gripping members. The base assembly includes a shaft and a coupler attached to the shaft such that the coupler can be moved along the shaft. The paddles are movable between an open position, a closed position and a bailout position. The paddles and the gripping members are configured to attach to the native valve of the patient. Movement of the coupler along the shaft causes the paddles to move between the open position, the closed position, and the bailout position. When the paddles are in the bailout position, a bailout angle between each paddle of the pair of paddles and the shaft is greater than or equal to 120 degrees.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: April 13, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Asher L. Metchik, Gregory Scott Tyler, II, Matthew T. Winston, Sergio Delgado, Lauren R. Freschauf, Eric R. Dixon, Alexander J. Siegel
  • Patent number: 10966821
    Abstract: Embodiments include prosthetic valves and related methods. In an embodiment, an implantable valve is included having a frame that includes a plurality of frame struts. The frame can define a central lumen. An outer skirt can be disposed on an abluminal surface of the frame. The outer skirt can include a flap having a first end and a second end. The first end of the flap can be fixed to the abluminal surface of the frame and the second end can be free to move away from the abluminal surface of the frame. Other embodiments are also included herein.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: April 6, 2021
    Assignee: Symetis SA
    Inventor: Stephane Delaloye
  • Patent number: 10966827
    Abstract: A method of implanting a prosthetic mitral valve includes advancing a delivery apparatus into a left side of a patient's heart and deploying a support structure from the delivery apparatus. The support structure extends around native mitral valve leaflets such that the native leaflets are disposed radially within the support structure. The method also includes advancing a prosthetic heart valve within the native leaflets. The prosthetic heart valve is separate from the support structure and includes an annular frame and a valve structure positioned within the annular frame, and prosthetic heart valve is in a radially collapsed configuration. The method further includes expanding the prosthetic heart valve from the radially collapsed configuration to a radially expanded configuration. In the radially expanded configuration, the annular frame of the prosthetic heart valve engages the native leaflets and is separated from the support structure by the native leaflets.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: April 6, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Francesco Maisano, Oded Meiri
  • Patent number: 10966830
    Abstract: An instrument for repairing an atrioventricular heart valve, the instrument including a tubular element having an outer, distal end; a distal implant part arranged in the tubular element; an artificial chord arranged in the tubular element; a proximal implant part arranged in the tubular element; and, an anchor carrier arranged in the tubular element. The distal implant part and the proximal implant part are arranged in the tubular element beside one another, with the distal implant part being closer to the distal end of the tubular element than the proximal implant part The proximal implant part is assembled with the anchor carrier inside the tubular element so that the tubular element prevents the proximal implant part from escaping from the anchor carrier as long as the anchor carrier is within the tubular element.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: April 6, 2021
    Assignee: COREMEDIC AG
    Inventors: Silvio Schaffner, Tobias Aeschlimann, Oliver Wüthrich, Thomas Bauer
  • Patent number: 10952854
    Abstract: A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: March 23, 2021
    Assignee: The Provost, Fellows, Foundation Scholars and the Other Members Of Board, of the College of the Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin (TCD)
    Inventors: Paul Heneghan, Bruce Murphy, Lucy O'Keeffe, Martin Quinn, Conor Quinn
  • Patent number: 10939999
    Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: March 9, 2021
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Jose L. Navia, Ji-Feng Chen, Shengqiang Gao, Brian L. Davis, Samantha Stucke
  • Patent number: 10932906
    Abstract: An assembly for transvascular replacement of a native aortic heart valve can have a radially collapsible and self-expandable prosthetic heart valve and a delivery apparatus. The valve can have an annular metal frame made of a shape-memory material with a plurality of posts extending from an end portion of the frame. The delivery apparatus can have a shaft comprising a valve connection portion that is releasably coupled to the posts of the valve. The valve connection portion can have a plurality of discrete radially facing recesses that receive the posts. The delivery apparatus can have a delivery sheath that is positioned around the prosthetic heart valve and the valve connection portion of the shaft to maintain the prosthetic heart valve in a radially compressed state and maintain the posts within the recesses. The delivery apparatus can cause relative axial motion between the delivery sheath and the valve.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: March 2, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Alon, Netanel Benichou, Oded Meiri
  • Patent number: 10925728
    Abstract: Methods of transcatheter delivery of a prosthetic heart valve. A distal region of a guide member assembly is advanced into a heart of a patient. The distal region is docked to native anatomy of the heart. A delivery device, including a collapsed prosthetic heart valve, is advanced over the docked guide member assembly. The collapsed prosthetic heart valve is located at an implantation site. The prosthetic heart valve is deployed from the delivery device, and then the delivery device is removed from the patient. At least a portion of the guide member assembly is removed from the patient. In some embodiments, the docking structure is docked to one or more of native mitral valve leaflets, chordae in the left ventricle, or walls of the left ventricle as part of a transseptal mitral valve delivery procedure.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: February 23, 2021
    Assignee: Medtronic Vascular, Inc.
    Inventors: Marc A. Anderson, Grainne Teresa Carroll, Paul Devereux, Niall Duffy, Matthew Fleming, Alexander J. Hill, Elliot J. Howard, James R. Keogh, Marian Patricia Lally, Luke Lehmann, Jeffrey Madden, Kevin M. Mauch, Ciaran McGuinness, Brian T. McHenry, Karl L. Olney, Geoffrey Orth, Edward Sarnowski, Elizabeth A. Schotzko, Benjamin Wong
  • Patent number: 10918481
    Abstract: A delivery tool includes a delivery capsule, disposed at a distal portion of the tool. The delivery capsule includes a proximal capsule-portion dimensioned to house a first part of an implant, and a distal capsule-portion dimensioned to house a second part of the implant; and an extracorporeal control portion, disposed at a proximal portion of the tool, the control portion including one or more controllers and one or more locks. The controllers are operatively coupled to the proximal and distal capsule-portions such that the proximal and distal capsule-portions are movable with respect to the implant via actuation of the controllers. The tool has sequential states in which movement of the proximal and distal capsule-portions is variously inhibited or facilitated.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: February 16, 2021
    Assignee: CARDIOVALVE LTD.
    Inventors: Ilia Hariton, Boaz Harari, Maxim Karalnik, Meni Iamberger
  • Patent number: 10898325
    Abstract: A medical device system may include a replacement heart valve implant including an expandable anchor member reversibly actuatable between a delivery configuration and a deployed configuration, wherein the replacement heart valve implant includes at least one locking mechanism configured to lock the expandable anchor member in the deployed configuration, and at least one actuator element configured to releasably engage the at least one locking mechanism and actuate the expandable anchor member between the delivery configuration and the deployed configuration. The at least one actuator element may include external threads on a distal portion of each actuator element and a ramp disposed proximal of the external threads.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: January 26, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael P. Calomeni, Takashi H. Ino, Randy S. Gamarra, Floriza Q. Escalona
  • Patent number: 10893940
    Abstract: A loop of material can be affixed to a cardiac annulus using a plurality of anchors. Each of these anchors is launched into the annulus by a respective anchor launcher, and each of these anchor launchers is triggered by pulling on a respective pull wire. This application is directed to methods and apparatuses that automate the pulling of these pull wires using a plurality of actuators. Each actuator includes a channel with a compressed spring disposed in a distal portion of the channel. A tab is affixed to the proximal end of the spring. When the tab is moved from a first position to a second position, the spring becomes free to expand. The expanding springs pull the pull wires in a proximal direction, which triggers the anchor launchers.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: January 19, 2021
    Assignee: Cardiac Implants, LLC
    Inventor: David Alon
  • Patent number: 10888424
    Abstract: The present invention relates to a prosthetic mitral valve device for implanting at the native mitral valve region of a heart. The prosthetic mitral valve coaptation enhancement device comprises a main body consisting of a stentframe and a valve element attached thereto, wherein the main body has a sealing section and a valve-bearing section, the valve-bearing section; the shape of the sealing section of the main body, in the compressed state, has a form that is adapted to the coaptation zone of the native mitral valve during systole, and the sealing section of the main body, the radial rigidity of the stentframe is lower than the radial rigidity of the valve-bearing section; the prosthetic mitral valve coaptation enhancement device further comprises at least one anchoring element, which anchoring element is coupled to the main body and is capable to anchor the main body within the native mitral valve region of a heart.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: January 12, 2021
    Assignee: MEDIRA AG
    Inventors: Maximilian Kuetting, Emilia Kawa, Marcos Centola
  • Patent number: 10888420
    Abstract: Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: January 12, 2021
    Assignee: Medtronic Vascular, Inc.
    Inventors: Michael Bateman, Cynthia Clague, Jeffrey Sandstrom, Joel Racchini, James R. Keogh
  • Patent number: 10881510
    Abstract: A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: January 5, 2021
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Arshad Quadri, J. Brent Ratz
  • Patent number: 10869761
    Abstract: A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: December 22, 2020
    Assignee: Medtronic Vascular Galway
    Inventors: Marian Creaven, Marc Anderson, Kate Corish, Declan Costello, Niall Duffy, Joshua Dwork, John Gallagher, Patrick Griffin, Gavin Kenny, Deirdre McGowan Smyth, John Milroy, Jason Quill, Herinaina Rabarimanantsoa Jamous, Paul Rothstein, Jeffrey Sandstrom, Edmond Sheahan, Frank White