Combined With Surgical Tool Patents (Class 623/2.11)
  • Patent number: 9943409
    Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. A protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: April 17, 2018
    Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: June-Hong Kim, Robert J. Lederman, Ozgur Kocaturk
  • Patent number: 9931206
    Abstract: A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular valve in a connection channel, having a circumferential connection channel wall structure, between atrial and ventricular chambers of a heart, including an inner device to be disposed in the interior of the connection channel, the inner device having a circumferential support structure which is radially expandable and having a valve attached to the circumferential support structure, and an outer device to be disposed on the exterior of the connection channel, wherein the outer device at least partly extends around the inner device at a radial distance to the inner device, wherein the inner and outer devices form a securing mechanism for securing the circumferential connection channel wall structure therebetween.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: April 3, 2018
    Assignee: HIGHLIFE SAS
    Inventor: Josef Weber
  • Patent number: 9925045
    Abstract: A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: March 27, 2018
    Assignee: Medtronic Vascular Galway
    Inventors: Marian Creaven, Marc Anderson, Kate Corish, Declan Costello, Niall Duffy, Joshua Dwork, John Gallagher, Patrick Griffin, Gavin Kenny, Deirdre McGowan Smyth, John Milroy, Jason Quill, Herinaina Rabarimanantsoa Jamous, Paul Rothstein, Jeffrey Sandstrom, Edmond Sheahan, Frank White
  • Patent number: 9907652
    Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: March 6, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark Chau, Travis Zenyo Oba, Sergio Delgado, Robert C. Taft
  • Patent number: 9895215
    Abstract: The present invention relates generally to a method and apparatus for deploying and/or retrieving a vena cava filter in a vena cava using a system configured to: (i) maintain grip of the unsheathed filter in the vena cava until deliberately released, (ii) prevent premature release of the filter in the vena cava, and/or (iii) facilitate retrieval by first everting the filter, then withdrawing the filter through a guiding catheter (e.g., retrieval via eversion).
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: February 20, 2018
    Assignee: ADIENT MEDICAL, INC.
    Inventors: Mitchell Eggers, Jeremy Durack, Joseph Steele, Michael Hogan, Raymond Kirk, David Franklin
  • Patent number: 9895221
    Abstract: This invention relates to the design and function of a device which allows for retrieval of a previously implanted valve prosthesis from a beating heart without extracorporeal circulation using a transcatheter retrieval system, including a guide component to facilitate the compression of the valve and retraction into a retrieval catheter, as well as an improved prosthetic transcatheter heart valve having one or more of: a series of radially extending tines having a loop terminus to improve sealing a deployed prosthetic mitral valve against hemodynamic leaking, a pre-compressible stent-in-stent design, or an articulating cuff attached to a covered stent-valve and a commissural sealing skirt structure attached to the underside of the articulating cuff.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: February 20, 2018
    Assignee: Tendyne Holdings, Inc.
    Inventor: Robert Vidlund
  • Patent number: 9889004
    Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly disposed within the stent, the valve assembly including a plurality of leaflets and a cuff annularly disposed about the stent. The cuff includes a surplus portion capable of forming a sealing structure having a diameter greater than a diameter of the proximal end of the stent when deployed.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: February 13, 2018
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Peter N. Braido
  • Patent number: 9877833
    Abstract: Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium, through the mitral valve, and into the left ventricle. A ventricular anchor is deployed from the catheter and into a wall of the left ventricle, leaving a ventricular suture attached to the ventricular anchor and extending proximally through the catheter. A leaflet anchor is deployed to secure a mitral valve leaflet to a leaflet suture, with the leaflet suture extending proximally through the catheter. The leaflet suture is secured to the ventricular suture to limit a range of travel of the leaflet in the direction of the left atrium. Also disclosed is an assembled in situ mitral valve leaflet restraint, having a neo papillary muscle and a neo chordae tendinea.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: January 30, 2018
    Assignee: Pipeline Medical Technologies, Inc.
    Inventors: Gordon B. Bishop, Randall T. Lashinski
  • Patent number: 9878127
    Abstract: The invention relates to an operating handle (10-1, 10-2) for manipulating a catheter tip (80-1, 80-2) of a catheter delivery system. The operating handle (10-1, 10-2) comprises a hand grip (11) designed to be held by a user, and a manipulating part (12) axially aligned with the hand grip (11). The manipulating part (12) is rotatable relatively to the hand grip (11) about a longitudinal axis (L) defined by the operating handle (10-1, 10-2). The operating handle (10-1, 10-2) comprises at least one sliding member (30, 40) operatively linked with the manipulating part (12) by means of a cam mechanism (50) such that, upon rotation of the manipulating part (12) relative to the hand grip (11), the at least one sliding member (30, 40) moves axially in the direction of the longitudinal axis (L).
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: January 30, 2018
    Assignees: JenaValve Technology, Inc., Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V.
    Inventors: Christoph Damm, Andreas Kamm, Michael Litzenburger, Thomas Töllner
  • Patent number: 9877821
    Abstract: The embolic protection device comprises an embolic filter attached to an inner sheath. The embolic filter includes at least a first catheter access port and a second catheter port. At least the first catheter port will typically be radially expandable to receive catheters of different diameters and will be located at an atypical end of an aero conical structure at a downstream end of the filter.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: January 30, 2018
    Assignee: Emboline, Inc.
    Inventors: Scott Russell, Amir Belson
  • Patent number: 9872768
    Abstract: Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: January 23, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: David J. Paul, Benjamin T. Sutton, Brian K. McCollum, Brian D. Brandt, Emma Leung, Kenneth M. Martin, Amr Salahieh, Daniel K. Hildebrand
  • Patent number: 9867695
    Abstract: A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: January 16, 2018
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Carla Stacchino, Giovanni Bergamasco, Gaetano Burriesci
  • Patent number: 9867700
    Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: January 16, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: George Bakis, Thanh V. Nguyen, Ly T. Phan, Asher L. Metchik
  • Patent number: 9867703
    Abstract: A device, kit and method may employ an implantable device (e.g., annuloplasty implant) and a tool to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). Tissue anchors are guided into precise position by an intravascularly deployed anchor guide frame and embedded in an annulus. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in a generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may move a posterior leaflet anteriorly and an anterior leaflet posteriorly, improving leaflet coaptation to eliminate mitral regurgitation.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: January 16, 2018
    Assignee: KARDIUM INC.
    Inventors: Jonathan Dahlgren, Douglas Goertzen, Daniel Gelbart, Kelly Watkinson, Derrick To
  • Patent number: 9861479
    Abstract: A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: January 9, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventor: Brian S. Conklin
  • Patent number: 9861478
    Abstract: An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: January 9, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Michael C. Murad, Emil Karapetian, Wesley V. Adzich
  • Patent number: 9855143
    Abstract: Methods and apparatuses for regulating aortic regurgitation are provided. A catheter shaft is advanced through vasculature so that a flexible occluding membrane coupled to the catheter shaft is positioned within the aorta, typically the ascending aorta above the Sinus of Valsalva and coronary ostia. Blood flow in the aorta causes the flexible occluding membrane to alternate between an expanded occluding configuration while in diastole and a collapsed lesser occluding configuration is systole. There flexible occluding membrane thereby acts as a temporary aortic valve. The flexible occluding membrane is generally conical in shape, with the tip of the cone disposed closer to the aorta than the proximal rim. In diastole, blood flow expands the flexible occluding membrane so that the proximal rim apposes the inner wall of the aorta. The flexible occluding membrane will have one or more openings to allow perfusion of the coronary arteries in diastole.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: January 2, 2018
    Assignee: HOCOR Cardiovascular Technologies LLC
    Inventor: Paul C. Ho
  • Patent number: 9848880
    Abstract: Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and/or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: December 26, 2017
    Inventors: James E. Coleman, Christy Cummins
  • Patent number: 9844436
    Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: December 19, 2017
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ruggero De Paulis, Michael C. Murad
  • Patent number: 9839519
    Abstract: Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow body member including a plurality of regions. Adjacent regions cooperate with one another to change the body member from an elongate insertion geometry to an annular operable geometry. Adjacent regions are coupled by a biasing element or a stepped connector to allow expansion to an expanded state and contraction to a contracted state in the annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the body member and having a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. An angled ring closure lock allows coupling of the ends of an annuloplasty ring at an apex of a D-shape annular operable geometry.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: December 12, 2017
    Assignee: VALCARE, INC.
    Inventors: Samuel M. Shaolian, Jeffrey P. DuMontelle, Nadav Yellin, Victor S. Packham, Hung H. Cao
  • Patent number: 9833315
    Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: December 5, 2017
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli, Lucian Lozonschi, Georg Lutter
  • Patent number: 9827094
    Abstract: Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having a leaflet frame and a leaflet construct. The leaflet construct is at least partially coupled to a leaflet frame outer side of the leaflet frame and being coupled thereto by a retention element.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: November 28, 2017
    Assignee: W. L. Gore & Associates, Inc.
    Inventor: Nathan L. Bennett
  • Patent number: 9827097
    Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: November 28, 2017
    Assignee: Medtronic Ventor Technologies Ltd.
    Inventors: Yosi Tuval, Ido Kilemnik, Raphael Benary
  • Patent number: 9820852
    Abstract: A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end. The sealing structure may have an outer edge remote from the inner edge. The sealing structure may have a collapsed condition with the outer edge disposed adjacent the outer surface of the cuff and an expanded condition with the outer edge spaced apart from the outer surface of the cuff.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: November 21, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Kent J. Smith, Andrea L. McCarthy, Mina S. Fahim
  • Patent number: 9814576
    Abstract: Apparatus, systems, and methods are provided for percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer tube, an inner body member, and an anchor deployment system. The outer tube includes a plurality of windows and has an axis along its length. The internal body member includes a plurality of anchors formed perpendicular to the axis. The anchor deployment system selectively rotates the internal body member with respect to the axis of the outer tube. The rotation deploys the plurality of anchors through the plurality of windows.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: November 14, 2017
    Assignee: VALCARE, INC.
    Inventors: Nadav Yellin, Samuel M. Shaolian, Jeffrey P. Dumontelle
  • Patent number: 9814574
    Abstract: The present disclosure provides aortic valve prosthetic devices that are constructed in a non-axisymmetric shape, or are expandable to a non-axisymmetric shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to a non-axisymmetric cross-section geometry.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: November 14, 2017
    Assignee: Biostable Science & Engineering, Inc.
    Inventors: J Scott Rankin, Al Beavan, William E. Cohn
  • Patent number: 9801710
    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: October 31, 2017
    Assignee: Edwards Lifesciences Corporation
    Inventors: Teodoro S. Jimenez, Mark Dehdashtian, Raffaele Mazzei
  • Patent number: 9801711
    Abstract: A device and method for controlling commissural tip deflection of a prosthetic valve, thereby both preventing failure due to repeated movement and/or uneven loading of the commissural points and also improving coaptation of the valve leaflets, including connecting reinforcing material between the commissural points so a spring-like span is created across the points. The spanning material may be in the form of a ring that is lashed, sewn or otherwise connected to the commissural points. The reinforcing material may form curved segments between the commissural points that extend outwardly to form sinuses behind the leaflets of the prosthetic valve. The reinforcing material may also extend in an upstream direction to avoid interfering with blood flowing out of the prosthetic valve.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 31, 2017
    Assignee: HLT, Inc.
    Inventor: John Gainor
  • Patent number: 9788946
    Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: October 17, 2017
    Assignee: Edwards Lifesciences Corporation
    Inventors: Donald E. Bobo, Jr., Assaf Bash, Louis A. Campbell, Alison S. Curtis, Tak G. Cheung, John F. Migliazza
  • Patent number: 9788945
    Abstract: The invention relates to a catheter for the transvasculur implantation of prosthetic heart valves, in particular comprising self-expanding anchorage supports (10), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation. To achieve this, according to the invention a prosthetic heart valve comprising anchorage supports is temporarily housed in a folded form in a cartridge-type unit (4) riming the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system (1), which comprises a flexible region (9) that can be guided through the aorta.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: October 17, 2017
    Assignee: JENAVALVE TECHNOLOGY, INC.
    Inventors: Rüdiger Ottma, Robert Moszner, Hans-Reiner Figulla, Markus Ferrari, Christoph Damm
  • Patent number: 9788931
    Abstract: A holder for heart valve prostheses, the holder including a hub portion having a longitudinal axis, an engagement portion coupled to the hub portion and including plural L-shaped finger members variably positionable relative to the hub portion between a collapsed condition wherein the finger members are closed onto the hub portion and an expanded condition wherein the finger members radially protrude with respect to the hub portion to engage a heart valve prosthesis.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: October 17, 2017
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Giovanni Giordano, Paolo Gaschino, Giovanni Rolando, Arnaldo Giannetti
  • Patent number: 9770328
    Abstract: A heart valve implant has a body sized and configured to rest near or within a heart valve annulus. A plurality of spaced-apart retainers extend outwardly from the body to contact tissue near or within the heart valve annulus. The retainers are sized and configured to secure the body to the heart valve annulus. The implant can be secured, e.g., without the use of sutures.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: September 26, 2017
    Assignee: MVRx, Inc.
    Inventor: John A. Macoviak
  • Patent number: 9763816
    Abstract: A first endoluminal prosthesis coupled to an inner catheter and a dilator tip is delivered to the body vessel via a guidewire and a delivery sheath in a conventional manner. After deployment of the first endoluminal prosthesis at the target site, the dilator and catheter are retracted from the body, leaving the delivery sheath in place. A second endoluminal prosthesis is housed within a peel-away sheath without a catheter or dilator tip, and is mated to the delivery sheath outside the patient. The second prosthesis is advanced from the peel-away sheath into the delivery sheath without the use of a dilator tip or catheter. As the second prosthesis is advanced into the delivery sheath from the peel-away sheath, the peel-away sheath is peeled away. The second prosthesis is advanced through the delivery sheath and delivered into an overlapping engagement with the first prosthesis.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 19, 2017
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventor: Blayne A. Roeder
  • Patent number: 9757230
    Abstract: A prosthetic heart valve having a cuff attached to a stent provides a seal for preventing paravalvular leakage. The cuff may be constructed from known sealing materials to fill in and around paravalvular leakage gaps, while continuously collapsing down into a low profile volume within the stent. The cuff is coupled circumferentially about the stent by members which may be in the nature of dimension and/or shape memory material having a tensioned and relaxed state. The members may be in the form of elongated elastic members or coiled members. When in the tensioned state, the cuff is located within the stent volume to provide a low profile prosthetic heart valve. Upon relaxing of the members, the cuff is pulled over the abluminal surface of the stent to form a cuff seal circumscribing the stent for preventing paravalvular leakage.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: September 12, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Mina S. Fahim, Peter N. Braido
  • Patent number: 9744036
    Abstract: A valve prosthesis and methods for implanting the prosthesis are provided. The prosthesis generally includes a self-expanding frame and two or more engagement arms. A valve prosthesis is sutured to the self-expanding frame. Each engagement arm corresponds to a native mitral valve leaflet. At least one engagement arm immobilizes the native leaflets, and holds the native leaflets close to the main frame. The prosthetic mitral valve frame also includes two or more anchor attachment points. Each anchor attachment point is attached to one or more anchors that help attach the valve prosthesis to the heart.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: August 29, 2017
    Assignee: Medtronic Vascular Galway
    Inventors: Niall Duffy, Gavin Kenny, Fabio Bartolozzi
  • Patent number: 9744035
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: August 29, 2017
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Amr Salahieh, Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Dwight P. Morejohn, Kenneth J. Michlitsch
  • Patent number: 9737264
    Abstract: An implantable device system includes an implantable device, such as an annuloplasty ring, for controlling at least a shape and/or size of a heart valve annulus. The implantable device includes an arcuate body and an adjustment system configured to adjust the shape and/or size of the arcuate body. An adjustment tool is configured to be coupled to the adjustment system so that the adjustment tool can be used to activate and control adjustment of the arcuate body. A sensor system is configured to be coupled to the implantable device. The sensor system includes a first sensor configured to measure physiological data at an inflow portion of the valve annulus when the implantable device is implanted into the valve annulus, and a second sensor configured to measure physiological data at an outflow portion of the valve annulus when the implantable device is implanted into the valve annulus.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: August 22, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Chad Joshua Green, Neelakantan Saikrishnan, Mina S. Fahim
  • Patent number: 9724196
    Abstract: An annuloplasty ring holder including a head having an upper surface and an annuloplasty ring receiving surface facing opposite the upper surface. The annuloplasty ring holder also includes means for attaching an annuloplasty ring to the annuloplasty ring receiving surface. The means for attaching an annuloplasty ring to the annuloplasty ring receiving surface may include one or more suture guides operatively associated with the head and configured to position one or more sutures to removably associate an annuloplasty ring with the annuloplasty ring receiving surface. The head may include a central hub and more than one spoke radiating out from the central hub. If the head is thus configured, each spoke will include a portion of the annuloplasty ring receiving surface.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: August 8, 2017
    Assignee: Medtronic, Inc.
    Inventors: John T. M. Wright, Hieu Cong Nguyen
  • Patent number: 9724224
    Abstract: A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can include a planet carrier, at least one planet gear operatively coupled to the planet carrier, a sun gear shaft operatively engaged with the planet gear, a ring gear operatively engaged with the planet gear, a first clutch driver, and a second clutch driver. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: August 8, 2017
    Assignee: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: Matthew J. Gillick, Michael L. Green
  • Patent number: 9700410
    Abstract: A catheter adapted for placement in the ascending aorta comprises a central catheter mechanism and a balloon structure or other occluding structure at its distal end. The catheter may be placed over the aortic arch such that the occluding structure is placed in the ascending aorta just above the Sinus of Valsalva and coronary ostia. Once in place, the occluding structure is inflated to control blood flow through the aorta during aortic valve ablation and replacement protocols.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: July 11, 2017
    Assignee: HOCOR Cardiovascular Technologies LLC
    Inventor: Paul C. Ho
  • Patent number: 9700732
    Abstract: A retrieval device and an associated implantable cardiac pacing device. The retrieval device includes a retrieval catheter and a snare advanceable from the distal end of the retrieval catheter. The snare has a loop configured to be coupled to the docking member to draw the implantable cardiac pacing device into the lumen of the retrieval catheter. The retrieval catheter includes a retention feature in the lumen configured to engage the head portion of the docking member to facilitate retention of the implantable cardiac pacing device in the lumen after drawing the implantable cardiac pacing device into the lumen of the retrieval catheter with the snare.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: July 11, 2017
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Brian L. Schmidt, Dana Sachs
  • Patent number: 9687341
    Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly including a plurality of leaflets, the valve assembly being disposed within the stent. The heart valve further includes a plurality of elongated legs each with a first end coupled to the stent and a free end, the elongated legs being configured to transition from an extended configuration to a relaxed configuration. A sealing portion connected to the plurality of legs forms a sealing structure when the legs transition to the relaxed configuration to reduce perivalvular leakage between the implanted valve and surrounding tissue.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: June 27, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Yousef F. Alkhatib, Tracee Eidenschink
  • Patent number: 9681864
    Abstract: Apparatus and methods for performing a non-invasive procedure to repair a cardiac valve are described herein. In some embodiments, apparatus and methods are described herein for repairing a mitral valve using an edge-to-edge repair to secure the mitral valve leaflets. Implant securing devices are also described that can be used during a procedure to repair a mitral valve. In some embodiments, an implant securing device includes an outer member and an inner member movably disposed within the outer member. The inner member can be used to hold or secure a suture extending from an implant deployed on an atrial side of a leaflet of a mitral valve, and the outer member can be used to push or move a half hitch knot toward a ventricular side of the leaflet, which can be used to secure the implant in the desired position.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: June 20, 2017
    Assignees: Harpoon Medical, Inc., University of Maryland, Baltimore
    Inventors: James Gammie, Peter Wilson, Peter Boyd, William Niland
  • Patent number: 9675454
    Abstract: This invention relates to a delivery apparatus and method for deployment of a mitral valve replacement.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: June 13, 2017
    Assignee: Tendyne Holdings, Inc.
    Inventors: Robert Vidlund, Kemal Schankereli
  • Patent number: 9675451
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: June 13, 2017
    Assignee: Medtronic CV Luxembourg S.a.r.l.
    Inventors: Kshitija Garde, Joel Racchini, Paul Rothstein, Jeffrey Sandstrom
  • Patent number: 9642607
    Abstract: A dilation system for accessing a surgical target site to perform surgical procedures. In one version, the dilation system includes a dilation assembly and an actuating mechanism. The dilation assembly comprises plurality of dilator segments. The actuating mechanism is operably associated with the dilator segments so as to cause the dilator segments to move from a collapsed state to an expanded state.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: May 9, 2017
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventor: Zoher Bootwala
  • Patent number: 9636441
    Abstract: Miniature axial flow pumps are implanted inside the heart or major arteries to provide hemodynamic support. These pumps commonly utilize tubular blood conduit tubes to transport blood across the aortic valve. The valve leaflets themselves are very thin and flexible, and will seal against the conduit if it is centered within the valve orifice. If the conduit is not centered, a leaflet can be pushed to the side of the aorta, preventing the leaflets from sealing and providing a path for backflow. If the blood flow conduit remains pushed against the side of the valve for a long period of time, thrombus may form in the crevice between the conduit and the aorta, causing serious thromboembolic events such as stroke, if the thrombus breaks free. The present invention provides a conduit support device that retains the conduit centered within the annulus of the natural heart valve.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: May 2, 2017
    Inventor: Robert Jarvik
  • Patent number: 9629714
    Abstract: A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: April 25, 2017
    Assignee: Edwards Lifesciences PVT, Inc.
    Inventors: Brice Letac, Alain Cribier
  • Patent number: 9592121
    Abstract: The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: March 14, 2017
    Assignee: Middle Peak Medical, Inc.
    Inventor: Alexander K. Khairkhahan
  • Patent number: RE46668
    Abstract: An improved holder and method for implanting a tissue-type prosthetic mitral heart valve that prevents suture looping and may also constrict the commissure posts of the valve. An upstanding or shaft member axially positioned on the holder causes the lengths of attachment sutures to extend axially beyond the commissure post tips to create a tent and prevent looping of any of an array of pre-implanted sutures around the tips during deployment of the valve. The shaft member may be axially movable such that it can be initially retracted and then actuated just prior to valve deployment. The shaft member may have notches on its distal tip for capturing the attachment sutures, which are crossed over along the valve axis to ensure engagement by the notches. The attachment sutures may be strands or filaments, or may be wider bands of flexible biocompatible material. If bands are used, they desirably cover the commissure post tips to further help prevent suture looping thereover.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: January 16, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Robert Stobie, Ralph Kafesjian, Diana Nguyen-Thien-Nhon, Robert Ian Lister, Andrzej Skoskiewicz, Adrian Benton James, Aaron Ernesto Sklar, Banny Banerjee