Adjustable Patents (Class 623/2.37)
  • Patent number: 11364120
    Abstract: An apparatus for augmenting the length of native chordae tendineae to restore physiological leaflet coaptation. The apparatus includes a delivery device having a lumen therein which at least partially houses a prosthetic cord. The prosthetic cord has a first end with a first clasp configured to attach to a native chordae tendineae and a second end with a second clasp configured to attach to the native chordae tendineae. The native chordae tendineae is severed between the first clasp and the second clasp, and the length of the prosthetic cord between the first clasp and the second clasp is adjusted until physiological leaflet coaptation is restored.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: June 21, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Jay Reimer
  • Patent number: 11357629
    Abstract: A method of treating diastolic heart failure includes implanting a cardiac implant in a heart of a subject diagnosed as suffering from diastolic heart failure. A superior portion of a flexible tether of the cardiac implant is anchored to one or more left-atrial sites of one or more walls of the left atrium. An inferior portion of the flexible tether is anchored to a site of a wall of a mid third of the left ventricle, of a wall of an apical third of the left ventricle, and/or of a papillary muscle of the left ventricle. As a result, the flexible tether reduces a volume of the left atrium during at least a portion of ventricular diastole of each cardiac cycle, thereby enhancing ventricular filling. Other embodiments are also described.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: June 14, 2022
    Assignee: RAINBOW MEDICAL LTD.
    Inventor: Yossi Gross
  • Patent number: 11259926
    Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An illustrative annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. The disclosure also provides improved techniques for cardiac pacing.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: March 1, 2022
    Assignee: Transmural Systems LLC
    Inventors: Nasser Rafiee, Stuart MacDonald, Koosha Rafiee
  • Patent number: 11202709
    Abstract: Apparatus includes an implant including a flexible longitudinal member extending along a longitudinal length of the implant and a flexible contracting member extending alongside the longitudinal member and along the longitudinal length of the implant. The contracting member is configured to facilitate reduction of a perimeter of the implant by applying a contracting force to the longitudinal member in response to an application of force to the contracting member. The contracting member is disposed at a radially outer perimeter of the longitudinal member and configured to apply a pushing force to the longitudinal member responsively to the application of the force to the contracting member.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: December 21, 2021
    Assignee: Valtech Cardio Ltd.
    Inventors: Eran Miller, Amir Gross, Oz Cabiri, Iftah Beinart, Aviram Baum
  • Patent number: 11173029
    Abstract: A method for treating regurgitation of blood flow through a diseased heart valve is provided. The diseased heart valve including an annulus, an anterior valve leaflet, a posterior valve leaflet and a subvalvular apparatus. The method includes providing an apparatus comprising a substantially annular support member, at least one infra-annular support member securely connected thereto, and at least one anchoring element associated with the at least one infra-annular support member. The method further includes attaching the substantially annular support member to the annulus of the diseased heart valve and attaching proximal and distal ends of a prosthetic chordae tendineae to the at least one anchoring element and a papillary muscle, respectively, so that the papillary muscle is caused to move medially.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: November 16, 2021
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Jose L. Navia
  • Patent number: 11166812
    Abstract: Various systems, devices and methods associated with the placement of a dock or anchor for a prosthetic valve. The anchor can take the form of an anchor having multiple coils. The distal end portion of the anchor can be spaced radially outwardly from the next adjacent coil to help direct the anchor around native leaflets of a native valve. Various methods include different procedures for delivering the anchor and prosthetic valve.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: November 9, 2021
    Assignee: Mitral Valve Technologies Sari
    Inventors: Paul A. Spence, Landon H. Tompkins
  • Patent number: 11147671
    Abstract: Disclosed herein are methods, implants and systems for treatment of mitral valve prolapse by subannular fixation of the prolapsed mitral valve. The disclosure relates generally to the field of heart valve repair devices, methods and kits and more specifically to trans catheter methods and devices for insertion of tethers and anchors to the mitral valve leaflets for reduction the prolapsed mitral valve and subannular fixation of the prolapsed leaflet to treat mitral valve regurgitation.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: October 19, 2021
    Assignee: CREATIVE HEART VALVE SOLUTIONS LLC
    Inventors: Valavanur A. Subramanian, Nirav C. Patel
  • Patent number: 11103349
    Abstract: Disclosed herein are various embodiments directed to a device for minimally invasive medical treatment. The device being a hollow tube with a first end, a second end, and one or more anchors configured to extend outward from the exterior of the hollow tube. The hollow tube having a plurality of cutouts on the exterior, wherein the cutouts allow the hollow tube to be flexible. Additionally, the hollow tube may have at least one snap mechanism configured to connect the first end and the second end together.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: August 31, 2021
    Assignee: VALCARE, INC.
    Inventors: Nadav Yellin, Samuel M. Shaolian, Matan Gedulter, Boaz Schwarz, Daniel Rapoport, Avraham Eftel
  • Patent number: 11083580
    Abstract: Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: August 10, 2021
    Assignee: Pipeline Medical Technologies, Inc.
    Inventors: Cameron Paul Purcell, Erik Griswold, Gordon B. Bishop, Stephen McDaniel, Trung Ho Pham
  • Patent number: 11033391
    Abstract: Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: June 15, 2021
    Assignee: Heart Repair Technologies, Inc.
    Inventors: Valavanur A. Subramanian, Michael L. Reo, Gary Hulme, Thomas Afzal, Jeffrey Christian, Maurice Buchbinder
  • Patent number: 11033386
    Abstract: A system for repairing a native heart valve can comprise a first fastener, a second faster, a first leaflet brace, and a second leaflet brace. The first leaflet brace can be configured to extend partially around a first native leaflet. The second leaflet brace can be configured to extend partially around a second native leaflet. The first fastener can be configured to be deployed on respective first end portions of the first and second braces so as to connect the first end portions to each other. The second fastener can be configured to be deployed on respective second end portions of the first and second braces so as to connect the second end portions to each other. When the first end portions are connected to each other and the second end portions are connected to each other, the first and second leaflet braces encircle the first and second native leaflets.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: June 15, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventor: Yaron Keidar
  • Patent number: 11020230
    Abstract: The device (1) is intended to be positioned in a sealed introducer placed in a femoral vein in order to penetrate the left atrium (4) of the heart (3) by passing through the septal wall (5) thereof.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: June 1, 2021
    Assignees: CMI'NOV
    Inventors: Marco Vola, Bernard Pain
  • Patent number: 10980635
    Abstract: An annuloplasty device formed from a Nitinol stent frame that expands into contact with the annulus above the native leaflets. A torus balloon activates barbs along the perimeter to fasten the stent frame to the annulus. A cinch ring is placed under tension to reduce the perimeter of the stent frame. The cinch ring and torus balloon are implanted along with the stent frame.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: April 20, 2021
    Inventors: William Joseph Drasler, William Joseph Drasler, II
  • Patent number: 10966824
    Abstract: A heart valve prosthesis delivery system can include a first sheath, a second sheath, a check valve, a check valve control lines, and a heart valve prosthesis carried within the first sheath or the second sheath. The check valve can be carried within the first sheath or the second sheath. The check valve has a check valve frame and a cover component, and the check valve control lines can be coupled to the check valve frame and configured to be manipulated by a physician to control release of the check valve. In use, the check valve can be configured to be deployed within the native valve structure for minimizing back flow of blood during placement of the valve prosthesis when the native valve leaflets are rendered non-functional by the presence of the delivery system.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: April 6, 2021
    Assignee: Micor Limited
    Inventors: Ji Zhang, Brandon G. Walsh, Cheng Y. Yang, Jinhua Zhu
  • Patent number: 10945837
    Abstract: Systems and methods for docking a heart valve prosthesis. A system can include an anchor formed as multiple coils adapted to support a heart valve prosthesis with coil portions positioned above and below the heart valve annulus. At least one of the coil portions can normally be at a first diameter and be expandable to a second, larger diameter upon application of radial outward force from within the helical anchor. Methods can include delivering an anchor, positioning and implanting a heart valve prosthesis, and expanding the heart valve prosthesis inside the anchor.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: March 16, 2021
    Assignee: Mitral Valve Technologies Sarl
    Inventors: Paul A. Spence, Landon H. Tompkins
  • Patent number: 10925760
    Abstract: A prosthetic implant includes a circumferentially adjustable sealing collar and a rotatable sealer gear. The sealing collar has a central longitudinal axis. The rotatable sealer gear is coupled to and disposed within the sealing collar and configured to adjust the circumference of the sealing collar. The sealer gear is radially offset relative to the central longitudinal axis of the sealing collar. Rotating the sealer gear in a first direction relative to the sealing collar circumferentially expands the sealing collar. Rotating the sealer gear in a second direction relative to the sealing collar circumferentially contracts the sealing collar.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: February 23, 2021
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Richard George Cartledge, John P. Cartledge
  • Patent number: 10881508
    Abstract: A replacement valve for replacing a damaged heart valve having a plurality of cusps separating an upstream region from a downstream region of a passage. The replacement valve includes a flexible band having biocompatible scaffolding sized for contact with a wall surrounding the passage in the patient's heart. The valve includes a resilient element attached to the flexible band for expanding the flexible band to contact the wall of the passage. The valve includes regenerative struts spaced around the flexible band. Each strut extends from an outboard end joined to an inward face of the flexible band to a central end. The central ends of the struts are joined together. The valve includes a flexible regenerative membrane joined to adjacent struts. The membrane extends outboard to an inward face of the band. An outboard edge of the membrane is free to move between a closed position and an open position.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: January 5, 2021
    Inventor: Robert V. Snyders
  • Patent number: 10874515
    Abstract: A mitral cerclage annuloplasty apparatus comprises a tissue protective device and a knot delivery device. The tissue protective device comprises a first protective tube and a second protective tube. The knot delivery device comprises a tube wherein a loose knot is looped around its distal end through a hole and wherein tight knot is formed when the distal end of the tube is cut open. Alternatively, the knot delivery device comprises an inner tube and outer tube. The inner tube is insertable and rotatable inside the outer tube. When the tubes are in a closed position by rotating either the outer tube or the inner tube, a hole is created near its distal end. When the tubes are in open position by rotating either the outer tube or the inner tube, the hole joins the opening of the outer tube and lengthens.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: December 29, 2020
    Assignee: TAU-PNU MEDICAL CO., LTD.
    Inventor: June-Hong Kim
  • Patent number: 10849751
    Abstract: A device (100) for supporting a valve annulus is described that includes spaced apart support members (105) and a connecting member (110) extending between and connecting the support members. At least one adjustor (115) is also provided that is engaged with the connecting member and can be actuated to modify a length of the connecting member between two adjacent support members. In addition, each support member may include at least two channels extending through the support members at different heights with respect to an overall thickness of the respective support member. Each channel may receive a portion of the connecting member therethrough, and each support member may further include a passageway between the channels to allow selection of one of the channels. In this way, the device may be adjusted in at least two dimensions to support the valve leaflets and promote sufficient closure of the leaflets.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: December 1, 2020
    Assignee: JCOR-1, INC.
    Inventor: Jeko Metodiev Madjarov
  • Patent number: 10849749
    Abstract: Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: December 1, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Jason Quill, Cynthia Clague, Michael Green, Alexander J. Hill, Ana Menk, Paul Rothstein, Georg Bortlein
  • Patent number: 10828160
    Abstract: The present teachings provide devices and methods of treating a tricuspid valve regurgitation. Specifically, one aspect of the present teachings provides devices each includes a vascular anchor, an annulus anchor, and at least one tensioning member connecting with the vascular anchor or the annulus anchor. Another aspect of the present teachings provides methods of deploying a vascular anchor at a first treatment location inside the coronary sinus, and deploying an annulus anchor at a second treatment location across the tricuspid annulus. When both the anchors are pulled towards each other, the portion of the annulus between the two anchors is plicated, which improves the coaptation of the tricuspid valve leaflets.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: November 10, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Michael Sutherland, Steven Cahalane
  • Patent number: 10799354
    Abstract: Anchors for securing an implant within a body organ and/or reshaping a body organ are provided herein. Anchors are configured for deployment in a body lumen or vasculature of the patient that are curved or conformable to accommodate anatomy of the patient. Such anchors can include deformable or collapsible structures upon tensioning of a bridging element in a lateral direction, or segmented tubes that can be adjusted by tightening of one or more tethers extending therethrough. Such anchors can be used as a posterior anchor in a blood vessel in implant systems having a tensioned bridging element extending between the posterior anchor and an anterior anchor deployed at another location within or along the body organ. Methods of deploying such anchors, and use of multiple anchors or multiple bridging elements to a single anchor are also provided.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: October 13, 2020
    Assignee: MVRx, Inc.
    Inventors: Timothy R. Machold, David A. Rahdert, Robert T. Chang, Ganesh Manoharan
  • Patent number: 10786215
    Abstract: A portable X-ray imaging apparatus is prevented from losing a connection with a medical member when a detection element is set up in the proximity of the subject to carry out an X-ray imaging. The portable X-ray imaging apparatus 100 comprises an X-ray tube device 4 that irradiates an X-ray to a subject P, an X-ray receiver 6 that detects the X-ray that transmits the subject P, a housing 1b that houses the X-ray receiver 6 capable of being pulled out, and a control element 21 that provides an alarm to prompt paying attention based on the connecting information 30a relative to a connection of the medical member with the subject P.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: September 29, 2020
    Assignee: SHIMADZU CORPORATION
    Inventor: Toshiaki Nakamura
  • Patent number: 10758354
    Abstract: An adjustable annuloplasty device comprising a tube having a basically annular shape or adopted to be brought into an annular shape. At least one portion, preferably three portions, of an outer wall or the whole outer wall of the tube is more rigid than opposite portion(s) of an inner wall or the whole inner wall. The inner wall is arranged nearer to an inside area defined by the annular shape than the outer wall. The inner wall is adapted to be displaced inwardly at least along less rigid portion(s) of the circumference upon actuation by at least one actuation element while the outer wall remains basically constant.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: September 1, 2020
    Assignee: KEPHALIOS S.A.S.
    Inventor: Daniel Hayoz
  • Patent number: 10751172
    Abstract: A heart valve assembly includes a heart valve, a self-expandable and collapsible stent, and a sealing member. The stent includes an inflow end and an outflow end and is configured to support the heart valve internally. The sealing member is connected to and extends circumferentially around the stent. The sealing member includes a plurality of radially outward extending protrusions comprising a fold of material of the sealing member.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: August 25, 2020
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Andrea N. Para
  • Patent number: 10722349
    Abstract: A prosthetic valve including an inner frame, an outer frame, and a connection assembly interconnecting the frames. The inner frame defines an interior volume for receiving a valve structure within the interior volume. The outer frame surrounds the inner frame. The inner and outer frames are each configured to be transitionable between compressed and expanded conditions. The prosthetic heart valve provides a initial deployed state in which the inner and outer frames are in the expanded condition, and a radial shape of the outer frame is adjustable via the connection assembly to a final deployed state. A shape of the outer frame can be adjusted upon implant to enable radial anchoring at the native annulus, while addressing possible non-uniformities of the native annulus and possible anatomical concerns such as LVOT obstruction.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: July 28, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventors: Frank White, Paraic Frisby, James R. Keogh
  • Patent number: 10722363
    Abstract: Apparatus, systems, and methods are provided for percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer tube, an inner body member, and an anchor deployment system. The outer tube includes a plurality of windows and has an axis along its length. The internal body member includes a plurality of anchors formed perpendicular to the axis. The anchor deployment system selectively rotates the internal body member with respect to the axis of the outer tube. The rotation deploys the plurality of anchors through the plurality of windows.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: July 28, 2020
    Assignee: VALCARE, INC.
    Inventors: Nadav Yellin, Samuel M. Shaolian, Jeffrey P. Dumontelle
  • Patent number: 10687942
    Abstract: Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. A protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: June 23, 2020
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: June-Hong Kim, Robert J. Lederman, Ozgur Kocaturk
  • Patent number: 10667904
    Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: June 2, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
  • Patent number: 10548729
    Abstract: An implant structure includes a contracting mechanism, including a rotatable structure for contracting the implant structure, and a locking mechanism. A rotation tool is configured to engage and rotate the rotatable structure. A longitudinal guide member is removably coupled to the contracting mechanism, configured to guide the rotation tool to the rotatable structure, and includes a distal force applicator. The rotation tool is axially moveable with respect to the guide member. The contracting mechanism is arranged such that the locking mechanism is (a) unlocked when the guide member is coupled to the contracting mechanism in a first state, thereby allowing the rotatable structure to rotate, and (b) locked when (i) the guide member is coupled to the contracting mechanism in a second state, thereby restricting the rotation of the rotatable structure, and (ii) the guide member is not coupled to the contracting mechanism, thereby restricting the rotation of the rotatable structure.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: February 4, 2020
    Assignee: Valtech Cardio, Ltd.
    Inventors: Yuval Zipory, Oz Cabiri, Yossi Gross, Tal Hammer, Amir Gross, Francesco Maisano, Eran Miller, Yoseph Weitzman, Aram Ayvazian
  • Patent number: 10512536
    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: December 24, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Teodoro S. Jimenez, Mark M. Dehdashtian, Raffaele Mazzei
  • Patent number: 10507097
    Abstract: Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: December 17, 2019
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Richard George Cartledge, John P. Cartledge
  • Patent number: 10500048
    Abstract: The invention relates in some aspects to a device for use in the transcatheter treatment of mitral valve regurgitation, including steerable guidewires, implantable coaptation assistance devices, anchoring systems for attaching a ventricular projection of an implantable coaptation device, a kit, and methods of using an implantable coaptation assistance device among other methods.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: December 10, 2019
    Assignee: Polares Medical Inc.
    Inventors: Alexander K. Khairkhahan, Michael D. Lesh
  • Patent number: 10456257
    Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: October 29, 2019
    Assignee: Cardiac Dimensions Pty. Ltd.
    Inventors: Mark L. Mathis, Leonard Kowalsky, David G. Reuter, Cruz Beeson
  • Patent number: 10456244
    Abstract: In a surgical method for improving cardiac function, an implantable scaffold or valve support device is inserted inside a patient's heart and attached to the heart in a region adjacent to a natural mitral or other heart valve. The scaffold or valve support device defines an orifice and, after the attaching of the scaffold or valve support device to the heart, or temporary support while native valve leaflets and/or subvalvular structures are captured, a prosthetic or bio-prosthetic valve seated in the orifice, and the native valve may be retracted into the scaffold/replacement assembly to create a gasket for sealing the complex.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: October 29, 2019
    Inventor: Lon Sutherland Annest
  • Patent number: 10448944
    Abstract: One embodiment of the present invention includes a filamentary fixation system including a sleeve formed of filamentary material including an interior and an exterior surface along a length defined between a first end and a second end, the sleeve having a coating adapted to allow for tissue ingrowth, and a filament formed of filamentary material including a first free end and a second free end, and a length therebetween, at least a portion of the filament positioned within the interior of the sleeve.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: October 22, 2019
    Assignee: Howmedica Osteonics Corp.
    Inventors: José Raúl Marchand, Ryan E. Yearsley, Kyle Craig Pilgeram
  • Patent number: 10398553
    Abstract: The present disclosure relates to repair devices and methods for repair of regurgitant tricuspid valves. A repair method includes positioning a repair device at a tricuspid valve in a collapsed configuration. The repair device includes a proximal disk and a distal disk joined by a neck section. The distal disk is deployed by passing it from the collapsed state to an expanded configuration on a first side of the tricuspid valve. The proximal disk is then deployed by passing it from the collapsed state to an expanded configuration on a second side of the tricuspid valve so as to grasp all three tricuspid valve leaflets between the deployed distal disk and the deployed proximal disk.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: September 3, 2019
    Assignee: Evalve, Inc.
    Inventor: Koji J. Kizuka
  • Patent number: 10357365
    Abstract: An annuloplasty prosthesis and delivery system for implanting the prosthesis adjacent an annulus of a heart valve having leaflets for adjusting the annulus to improve valve function includes a ring prosthesis made of shape memory material and having tissue attachment members which attach to the annulus in the atrium and commissural legs extending from the ring between the leaflets and secure against the underside of the valve in the ventricle. The prosthesis is carried via an orientation loop and attaches to the heart tissue such that when the prosthesis is manipulated and relaxed the annulus is adjusted to reduce or eliminate regurgitation.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: July 23, 2019
    Assignee: Serca Biomedical, LLC
    Inventor: Stephen Kuehn
  • Patent number: 10327901
    Abstract: A prosthetic system for heart valve replacement comprises an annular support structure within which a valved prosthetic body can be expanded until it meets opposition. The annular support is provided in ring segments having terminal connectors for forming, in the condition of use of the prosthetic system, a stable and durable annular structural continuity capable of withstanding the opposition exerted by the valved prosthetic body. The prosthetic system is deployed using guide wires within a cardiac chamber guided through an introducer catheter having through lumens, within which at least two first guide catheters are positioned. These guide catheters have respective deflected or deflectable distal ends adapted to emerge from the distal end of the introducer catheter to convey and direct the distal ends of respective guide wires, placed within the guide catheters, towards a capture member of a capture system which is provided within the introducer catheter.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: June 25, 2019
    Assignee: INNOVHEART S.R.L.
    Inventors: Giovanni Righini, Sarah Zanon
  • Patent number: 10321989
    Abstract: The present disclosure relates to an arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve. With the method or the arrangement, leakage or regurgitation between a prosthetic heart valve and the surrounding valve tissue is prevented. In one embodiment, an arrangement for replacement or repair of a native heart valve is provided, which comprises a loop-shaped support 41 and a prosthetic heart valve 70 and wherein an outer segment 32 of the loop-shaped support 41 is positionable towards surrounding valve tissue of a native heart valve and wherein an outer surface 74 of the prosthetic heart valve 70 is positionable towards an inner segment 34 of the loop-shaped support 41 so as to prevent paravalvular leakage or regurgitation between the prosthetic heart valve 70 and the surrounding valve tissue of the native heart valve.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: June 18, 2019
    Assignee: Medtentia International Ltd Oy
    Inventor: Olli Keränen
  • Patent number: 10226342
    Abstract: Apparatus is provided, comprising a ring, comprising a plurality of struts arranged in a pattern of alternating peaks and troughs, each strut having a first end-portion and a second end-portion, each peak defined by convergence of adjacent first end-portions disposed at an angle with respect to each other, and each trough defined by convergence of adjacent second end-portions. The apparatus also comprises a plurality of anchors. Each anchor has a longitudinal axis, is configured to be driven along the longitudinal axis into tissue of the heart, and is coupled to the ring at a respective trough in a manner that facilitates (i) movement of the anchor along the longitudinal axis with respect to the trough, and (ii) deflection of the longitudinal axis with respect to the trough.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: March 12, 2019
    Assignee: Valtech Cardio, Ltd.
    Inventors: Meir Kutzik, Haim Brauon, Michael Levin, Alon Fogel, Ilia Hariton, Tal Reich
  • Patent number: 10226339
    Abstract: Various systems, devices and methods associated with the placement of a dock or anchor (72) for a prosthetic mitral valve (120). The anchor (72) may take the form of a helical anchor having multiple coils (104, 108) and/or a stent-like structure. Various methods include different levels of minimal invasive procedures for delivering the prosthetic valve anchor (72) and prosthetic valve (120), as well as tissue anchors for plication or other purposes to the mitral valve position in the heart (14).
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: March 12, 2019
    Assignee: Mitral Valve Technologies Sarl
    Inventors: Paul A. Spence, Landon H. Tompkins
  • Patent number: 10226343
    Abstract: An annuloplasty ring holder including a head having an upper surface and an annuloplasty ring receiving surface facing opposite the upper surface. The annuloplasty ring holder also includes means for attaching an annuloplasty ring to the annuloplasty ring receiving surface. The means for attaching an annuloplasty ring to the annuloplasty ring receiving surface may include one or more suture guides operatively associated with the head and configured to position one or more sutures to removably associate an annuloplasty ring with the annuloplasty ring receiving surface. The head may include a central hub and more than one spoke radiating out from the central hub. If the head is thus configured, each spoke will include a portion of the annuloplasty ring receiving surface.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: March 12, 2019
    Assignee: Medtronic, Inc.
    Inventors: John T. M. Wright, Hieu Cong Nguyen
  • Patent number: 10201424
    Abstract: A device for improving the function of a heart valve has a first and a second shape. The device comprises two contact points, and the device in the first shape exhibits a distance between the two contact points essentially corresponding to a distance between two commissures of the heart valve and the device in the second shape exhibits an increased distance between the contact points. The device is in the first shape arranged for insertion to the heart valve to establish a contact between the contact points and the commissures. The device is transferable from the first shape to the second shape, and the device is in the second shape arranged for extending in abutment with valve tissue throughout a cycle of heart action. The device may change the shape of the heart valve by stretching it between the commissures for improving the ability of the heart valve to close.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: February 12, 2019
    Assignee: Medtentia International Ltd., Oy
    Inventor: Olli Keränen
  • Patent number: 10195031
    Abstract: An implant for implantation around a circumferential tissue structure in a heart, includes a flexible elongated component having a longitudinal axis and a first distal end portion, a second distal end portion and an intermediate portion extending between the first and second distal end portions, and an inner lumen extending longitudinally between the first and second distal end portions and through the intermediate portion; and a locking member for allowing the first distal end portion to be fixedly connected to the second distal end portion so as to provide the elongated component as a closed loop. The first distal end portion is provided with a first distal opening which connects the inner lumen with an outside of the component. The second distal end portion is provided with a second distal opening which connects the inner lumen with the outside of the component.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: February 5, 2019
    Assignee: HIGHLIFE SAS
    Inventors: Malek Nasr, Georg Börtlein, Jean-Francois Ollivier, Philippe D'Hiver
  • Patent number: 10195026
    Abstract: Disclosed herein are prosthetic devices and related methods for implantation at the native mitral valve of the heart by drawing an atrial portion and a ventricular portion toward each other from opposite sides of the native mitral valve, clamping the native mitral valve therebetween. One or more retention members passing through the mitral valve orifice or through a puncture in the native valve anatomy can couple the atrial and ventricular members together and keep them anchored onto the native mitral valve anatomy. The atrial portion can seat against the atrial side of the mitral annulus while the ventricular portion can include hooks and/or a sub-annular ring that engage and capture the native mitral valve apparatus to provide anchorage. The described technology can avoid the need to use sutures to anchor a prosthetic device at the mitral valve region.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: February 5, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Emil Karapetian, Austin Bly, Stanton J. Rowe
  • Patent number: 10195029
    Abstract: A device for improving the function of a heart valve comprises: a support member formed from a shape memory material, and a restraining member providing a restraining action on a course of the support member. The support member may abut one side of the valve conforming to the shape of the valve annulus upon said shape memory material assuming an activated shape while the restraining member restrains the course of the support member. The restraining action is removable for allowing the support member to assume a desired, altered course. The restraining member may be biodegradable to be degraded within a patient or may be detachable from the support member to be withdrawn. The support member according to another embodiment presents a shape change in that an increased cross-section is associated with a shortened length of the support member. The support member according to yet another embodiment has a first and a second activated shape.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: February 5, 2019
    Assignee: Medtentia Internatinal Ltd Oy
    Inventor: Olli Keränen
  • Patent number: 10195032
    Abstract: A mitral cerclage annuloplasty apparatus comprises a tissue protective device and a knot delivery device. The tissue protective device comprises a first protective tube and a second protective tube. The knot delivery device comprises a tube wherein a loose knot is looped around its distal end through a hole and wherein tight knot is formed when the distal end of the tube is cut open. Alternatively, the knot delivery device comprises an inner tube and outer tube. The inner tube is insertable and rotatable inside the outer tube. When the tubes are in a closed position by rotating either the outer tube or the inner tube, a hole is created near its distal end. When the tubes are in open position by rotating either the outer tube or the inner tube, the hole joins the opening of the outer tube and lengthens.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: February 5, 2019
    Assignee: TAU PNU MEDICAL CO., LTD.
    Inventor: June-Hong Kim
  • Patent number: 10166099
    Abstract: The present invention provides an artificial heart valve annuloplasty ring, including an outer layer (6) and an annular main body (8) integrally formed from multiple ring sections, the outer layer (6) is a fiber fabric layer covered on the outside of the annular main body (8), the annular main body (8) includes a tube with a tube wall that has a slotted structure capable of adjusting the rigidity of the annuloplasty ring. The artificial heart valve annuloplasty ring provided in the present invention has a simple structure, easy-to-adjust rigidity, and does not need to separately design and manufacture a mold for the main body of the annuloplasty ring during manufacturing.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: January 1, 2019
    Assignee: KINGSTRONBIO (CHANGSHU) CO., LTD.
    Inventors: Chang Jin, Shengping Sam Zhong
  • Patent number: 10076413
    Abstract: Systems and methods treat a heart valve using a magnetically adjustable annuloplasty ring attached to or near a cardiac valve annulus. A changing magnetic field may be used to selectively increase or decrease a circumference of, or otherwise modify the shape of, the implanted annuloplasty ring. The adjustable annuloplasty ring includes a tubular body member, one or more adjustable members, and an internal magnet within the tubular body member. The tubular body member and the one or more adjustable members form a ring shape. The internal magnet is configured to rotate in response to a rotating external magnetic field. The internal magnet is coupled to the one or more adjustable members to change a dimension of the ring shape as the internal magnet rotates. A system for treating a heart valve may include an external adjustment device having one or more external magnets to generate the rotating external magnetic field.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: September 18, 2018
    Assignee: NuVasive Specialized Orthopedics, Inc.
    Inventors: Samuel Shaolian, Scott Pool, Ross Tsukashima, Daniel Anderson