Ceramic Patents (Class 623/23.56)
  • Patent number: 10513463
    Abstract: Disclosed are embodiments of a multi-phase ceramic material which can have advantageous properties as a thermal barrier coating. In particular, embodiments of the ceramic can have high fracture toughness as well as calcium, magnesium, and aluminum silicate corrosion resistance. The improved properties of the ceramic can make the material applicable as a coating on turbines, such as airplane and industrial turbines.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: December 24, 2019
    Assignee: Skyworks Solutions, Inc.
    Inventors: Michael David Hill, Jeffrey Alan Shunkwiler
  • Patent number: 10201433
    Abstract: In described embodiments, an implant has an outer perimeter. The implant includes a top surface extending generally in a first plane and a bottom surface extending in a second plane. The second plane extends obliquely with respect to the first plane. The first plane intersects the second plane outside the outer perimeter of the implant. A medial surface extends between the top surface and the bottom surface proximate to the intersection of the first plane and the second plane. A lateral surface extends between the top surface and the bottom surface distal from the intersection of the first plane and the second plane. An anterior surface extends a first distance between the top surface and the bottom surface between the medial surface and the lateral surface. A posterior surface extends a second distance between the top surface and the bottom surface between the medial surface and the lateral surface. The second distance is greater than the first distance.
    Type: Grant
    Filed: November 22, 2015
    Date of Patent: February 12, 2019
    Assignee: Tyber Medical LLC
    Inventor: Jeffrey Tyber
  • Patent number: 10172977
    Abstract: A synthetic osteoinductive porous biomaterial is provided comprising: a network of interconnected micropores, wherein the microporosity is 23% by volume or more; wherein the surface free energy of the biomaterial is 19 mJ/m or more; and the mean interconnection diameter and the mean interconnection diameter and the surface free energy are chosen to provide a permeability resulting from the micropores of 0.206 nm2 or greater and a capillary pressure difference in water of 3.7 kPa or more. The biomaterial contains hydroxyapatite and silicon.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: January 8, 2019
    Assignee: APATECH LIMITED
    Inventors: Thomas Buckland, Charles Campion
  • Patent number: 9636435
    Abstract: Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: May 2, 2017
    Assignee: LifeCell Corporation
    Inventors: Wendell Sun, Gary Monteiro
  • Patent number: 9421227
    Abstract: The invention relates to a biomaterial containing calcium phosphate, in particular hydroxyapatite or a material containing hydroxyapatite, such as biphasic calcium phosphates and calcium phosphate cements, and to the use thereof for the production of an implant or for fitting a prosthesis for the purpose of bone tissue regeneration.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: August 23, 2016
    Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de Nice
    Inventors: Thierry Balaguer, Nathalie Rochet, Georges Carle
  • Patent number: 9387274
    Abstract: A new material was assessed in a patellar reattachment model in sheep and evaluated using histology and biomechanical testing. Overall, these materials showed they produced minimal reactivity histologically. The new material had higher failure strength overall compared to a previous study with the control material as repairs completed with PLG/CS/TCP anchors were significantly stronger compared to repairs with PLLA anchors.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: July 12, 2016
    Assignee: Smith & Nephew, Inc.
    Inventors: Nicholas John Cotton, Melissa Jane Egan
  • Patent number: 9320828
    Abstract: The present invention is comprised within tissue engineering and, specifically, within bone regeneration. The invention relates to a porous three-dimensional matrix of monetite which is biocompatible, has structured porosity and is predefined and reabsorbable, as well as to the method of synthesis capable of producing said material and the applications thereof. These matrices are a perfect base for cell colonization and proliferation, allowing the application thereof in tissue engineering and bone regeneration as a result of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularization, etc.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: April 26, 2016
    Assignee: HISTOCELL, S.L.
    Inventors: Julio Font Pérez, Maria Begoña Castro Feo, Maite Del Olmo Basterrechea, Maria Dolores García Vázquez, Jorge Rubio Retama, Enrique López Cabarcos, Carmen Rueda Rodríguez, Faleh Tamimi Mariño, Mohammad Hamdan Ali Alkhraisat
  • Patent number: 9173981
    Abstract: Described herein are biocompatible compositions that contain a copolymer and a filler material. In particular, described herein are compositions that include a copolymer and a filler which may be a calcium salt. Also described herein are methods in which the compositions are used to attach soft tissue to bone.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: November 3, 2015
    Assignee: Smith & Nephew, INC.
    Inventors: Nicholas John Cotton, Melissa Jane Egan
  • Patent number: 9012043
    Abstract: A medical implant device or component thereof comprising a metal substrate and a coating layer structure provided on the substrate. The coating layer structure comprises an outermost layer of a ceramic material. A bonding structure is deposited between the metal substrate and the coating layer structure. The bonding structure comprises a chromium rich layer, which is deposited onto the metal substrate surface and has a higher concentration of chromium than the metal substrate, as well as a gradient layer having a composition gradient from the chromium rich layer towards the surface of the device providing increasing proportions of a gradient material which has structural correspondence with the layer of the coating layer structure that is most adjacent to the bonding structure.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: April 21, 2015
    Assignee: Sandvik Intellectual Property AB
    Inventors: Ola Wilhelmsson, Tom Eriksson, Per Mårtensson
  • Patent number: 9005286
    Abstract: The present invention involves tissue engineering constructs made from a new composite bone graft material made from biocompatible poly(D,L-lactic-co-glycolic acid) (PLGA) and bioceramic particles exposed on its surface using a gas foaming particle leaching (GF/PL) method and infused with collagen. Methods and apparatus for of forming scaffolds are also disclosed.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: April 14, 2015
    Assignee: Thierry Giorno
    Inventor: Thierry Giorno
  • Patent number: 8962749
    Abstract: The invention provides a ceramic green sheet having plasticity, punching property, and sinterability of satisfactory levels as well as a low percent (heat) shrinkage. In the production of a ceramic slurry serving as a raw material of the sheet, ingredients thereof are mixed under such conditions that the functional group ratio (polyol to isocyanate) is 1.5/11.5 to 11.5/11.5; the urethane resin formed from isocyanate and polyol has a repeating-unit-based molecular weight of 290 to 988; and the ratio by weight of the urethane resin to a ceramic powder falls within a range of 4.5 to 10 parts by weight of the urethane resin with respect to 100 parts by weight of the ceramic powder. A ceramic green sheet having, in well balance, all of the properties (i.e., plasticity, punching property, sinterability, and (heat) shrinkage) required for facilitating subsequent processes such as mechanical working and firing can be provided.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: February 24, 2015
    Assignee: NGK Insulators, Ltd.
    Inventors: Koji Kimura, Takuji Kimura, Tetsuya Onogi, Hidemi Nakagawa
  • Publication number: 20150025651
    Abstract: Sliceable bone repair material is a porous block-shaped scaffold containing a hydrogel, wherein the hydrogel is formed by Michael type addition of at least two precursor molecules. Said scaffold is made of a synthetic ceramic material and has interconnected macropores having a diameter above 100 ?m. In addition said scaffold has a total porosity of 60 to 80%. The total volume of the hydrogel is smaller than the total volume of the interconnected macropores.
    Type: Application
    Filed: February 12, 2013
    Publication date: January 22, 2015
    Inventors: Corinna Mauth, Aaldert-Rens Molenberg
  • Patent number: 8834576
    Abstract: Fired magnesium oxide stabilized zirconia ceramic body having a highly smooth, polished or otherwise equivalent surface has, on at least part of the surface, a metal/metal alloy coating. The fired ceramic body can be a magnesium oxide stabilized tetragonally toughened zirconia. The coating can be from a metal or metal alloy other than by tantalum vapor deposition, and can include a titanium metal or alloy. The coated magnesium oxide stabilized zirconia ceramic can be a tool or an orthopedic implant or component for an orthopedic implant, which can be a load bearing implant or component for a load bearing implant having an articular surface and a nonarticular surface where the metal or metal alloy coating is on at least part of the nonarticular surface. Plasma arc spraying under vacuum may be employed.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: September 16, 2014
    Inventor: Louis A. Serafin, Jr.
  • Publication number: 20140214174
    Abstract: A process for manufacturing a ceramic implant with a surface which forms a permanent bonding to bone cell tissues, the surface providing improved osseointegration, the process comprising the step of:—a pretreatment of the ceramic material with the surface wherein said surface of the ceramic material is exposed to a conditioning plasma, which is produced by means of direct current (DC) or alternating current (AC), such as high or radio frequency (HF, RF), or microwaves (MW) at a low pressure, followed by a second step;—a treatment with a reactive plasma in which an organic compound is added to the plasma for the at least partial application of an organic phase to said surface wherein the organic compound is selected from the group consisting of aliphatic amines, cyclic amines, unsaturated and aromatic amines as well as combinations thereof.
    Type: Application
    Filed: September 5, 2012
    Publication date: July 31, 2014
    Inventors: Andre Schöne, Jens Fischer, Karsten Schröder, Hartmut Steffen, Wilfried Besch, Andreas Vogelsang, Klaus-Dieter Weltmann, Barbara Nebe
  • Publication number: 20140214173
    Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.
    Type: Application
    Filed: March 27, 2014
    Publication date: July 31, 2014
    Inventors: Thomas E. Day, Erik M. Erbe, Steven B. Jung
  • Patent number: 8778822
    Abstract: The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an accelerator, a retarder, a surfactant, a foaming agent, a reactive alumina, water, a fiber, and a biologically active material, and combinations thereof. Ceramic compositions are provides as well as method of using the ceramic compositions and methods of manufacturing a ceramic porous body. The ceramic porous bodies of this invention may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: July 15, 2014
    Assignee: Cabertech, Inc.
    Inventor: Kenneth A. McGowan
  • Publication number: 20140180434
    Abstract: A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.
    Type: Application
    Filed: December 20, 2012
    Publication date: June 26, 2014
    Inventors: Thomas E. Day, Erik M. Erbe, Steven B. Jung
  • Patent number: 8734889
    Abstract: The invention relates to a ceramic implant, especially a dental implant, comprising a structured or porous surface for at least partially inserting into a bone. An especially advantageous surface is obtained when it is at least partially modified by a salt melt. These excellent osteointegration properties can be obtained by a method whereby the surface is modified in a salt melt at least in the regions exposed to the bones and/or soft tissue, optionally following a previous modification of the surface whereby material has been removed.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: May 27, 2014
    Assignee: Thommen Medical AG
    Inventors: Falko Schlottig, Thomas Hefti
  • Patent number: 8722073
    Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: May 13, 2014
    Assignee: Howmedica Osteonics Corp.
    Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
  • Patent number: 8673017
    Abstract: The object of the present invention is a process for obtaining a bone substitute of given chemical and physical characteristics and entirely similar to those of the mineral portion of natural bone tissue. The process substitutes Ca ions with Mg ions in a porous matrix; the process comprises a phase of contacting the matrix with a saline aqueous solution containing an effective quantity of Mg ions at a pressure greater than or equal to 1 bar.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: March 18, 2014
    Assignee: Fin-Ceramica Faenza S.p.A.
    Inventors: Roberta Martinetti, Daniele Pressato, Laura Dolcini, Sergio Di Fede
  • Publication number: 20140067082
    Abstract: The present disclosure is directed to a bioresorbable ceramic composition having a plurality of biocompatible ceramic granules, each of the granules having a coating of a plurality of calcium containing particles, where at least a portion of the particles are bound to at least a portion of an outer surface of each of the granules, and further where the composition is flowable in a dry state. The present disclosure is also directed to a three dimensional scaffold for bone repair that includes the bioresorbable composition, which upon implantation to a locus of repair defines an interconnected pore network between outer walls of the coated granules of the composition. Finally, the present disclosure is directed to methods of forming both the bioresorbable ceramic composition and the three-dimensional ceramic scaffold.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 6, 2014
    Inventors: Xinyin Liu, Mark Fulmer, Peter Schaut, Kevin Joye
  • Patent number: 8663337
    Abstract: A process for forming a ceramic layer comprising a compound of a metal on a deposition surface of a workpiece comprises providing a reactive gas, selecting the amounts of a vapor of the metal and ions of the metal relative to each other, generating the metal vapor, and projecting an ion beam of the metal ions. The metal vapor, the metal ions, and the reactive gas form the ceramic layer with a desired structure. The process may include the step of controlling a deposition surface temperature. In one embodiment, the metal vapor comprises zirconium vapor and the ion beam comprises zirconium ions. The relative amounts of the zirconium vapor and the zirconium ions are selected to form a zirconia ceramic layer on the deposition surface. The zirconia may have multiple crystal phases that are formed according to a predetermined ratio.
    Type: Grant
    Filed: March 6, 2012
    Date of Patent: March 4, 2014
    Assignee: Zimmer, Inc.
    Inventors: Jeffrey P. Anderson, Oludele O. Popoola
  • Publication number: 20140046453
    Abstract: The present invention relates to a new composition and medical implant made therefrom, the composition comprising a thick diffusion hardened zone, and preferably further comprising a ceramic layer. The present invention relates to orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition.
    Type: Application
    Filed: September 16, 2013
    Publication date: February 13, 2014
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Vivek PAWAR, Shilesh C JANI, Carolyn L WEAVER
  • Publication number: 20140031949
    Abstract: Bacterial growth or infection, especially with respect to an implant and/or tissue about the implant, can be ameliorated, controlled or eliminated by identifying a potential for or a presence of bacterial growth or infection with respect to tissue about an implant proposed for implantation; selecting as the implant a ceramic implant; and implanting the ceramic implant under conditions such that bacterial growth or infection, especially with respect to the implanted ceramic implant and/or tissue about the implanted ceramic implant, is ameliorated, controlled or eliminated at least in part from the presence of the implanted ceramic implant. Among ceramics that may be employed is a magnesium oxide stabilized transformationally toughened zirconia. The ceramic implant may be a prosthesis, which may be a load-bearing joint replacement implant or implant component.
    Type: Application
    Filed: June 25, 2013
    Publication date: January 30, 2014
    Applicant: Signal Medical Corporation
    Inventor: Louis A. Serafin, JR.
  • Patent number: 8623526
    Abstract: Disclosed are a gradient bioceramic coating comprising a rare earth oxide, a broadband laser method for preparing the bioceramic coating, and the use of the bioceramic coating in the field of medical materials.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: January 7, 2014
    Assignee: Guizhou University
    Inventors: Qibin Liu, Wenfei Li, Ling Wu
  • Patent number: 8623094
    Abstract: An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant comprising collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be “matched” to provide the implant with similar physical and/or chemical properties as the host tissue.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: January 7, 2014
    Assignee: Kensey Nash BVF Technology LLC
    Inventors: Douglas G Evans, Scott M. Goldman, Russell T. Kronengold
  • Patent number: 8609235
    Abstract: Provision of a porous ceramic material which rapidly induces bone tissue formation and has practical strength. A porous ceramic material 11 having substantially unidirectionally oriented pores 12, a porosity of 40-90%, and an average open area of one pore of 0.05×10?3-50×10?3 mm2 both in a first sectional surface perpendicular to the pore 12 orientation direction and a second sectional surface parallel to the first sectional surface and 5 mm distant from the first sectional surface in the pore 12 orientation direction. Using the material 11, when a cylindrical test piece (diameter 3 mm×height 5 mm, the pore 12 array direction as a height direction) made of the material is dipped in polyethylene glycol up to 1 mm from one end thereof, polyethylene glycol permeates through the whole test piece preferably within 30 seconds.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: December 17, 2013
    Assignees: Kuraray Co., Ltd., National Institute for Materials Science
    Inventors: Yuji Hotta, Yasushi Suetsugu, Masanori Kikuchi, Toshiyuki Ikoma, Tomoya Kuwayama, Takashi Makabe, Junzo Tanaka
  • Patent number: 8603183
    Abstract: A bilayered bone graft device includes a core portion comprising deminernalized gelatin and a shell portion surrounding the core portion. The shell portion includes a calcium silicate and the deminernalized gelatin in a range of 1 to 30 weight percent, and the calcium silicate has a molar ratio of calcium to silicon ranging from 10 to 0.1. The core portion and the shell portion are bound by the deminernalized gelatin without using a binder. In one embodiment of the present invention, the core portion is configured to provide buffering for receiving an insertion, and the shell portion is configured to provide a load-bearing structure.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: December 10, 2013
    Inventor: Shinn Jyh Ding
  • Patent number: 8603184
    Abstract: A kneadable and moldable bone-replacement material includes a mixture of calcium-containing ceramic particles and a hydrogel or a substance which can be swelled into a hydrogel. The ceramic particles are of fully synthetic origin and the individual ceramic particles have a structure which is at least partially cohesive and porous. In addition, the majority of the ceramic particles have a non-spheric shape.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: December 10, 2013
    Assignee: DePuy Synthes Products, LLC
    Inventors: Giancarlo Rizzoli, Thierry Stoll, Reto Luginbuehl, Marc Bohner
  • Publication number: 20130282134
    Abstract: Multi-layered prosthetic constructs, kits, and methods are disclosed. A prosthetic construct can include a first ceramic component having a first surface, the first ceramic component comprising a first ceramic material, and a second ceramic component having a second surface disposed on the first surface of the first ceramic component, the second ceramic component comprising a second ceramic material. The second ceramic material of the second ceramic component can exert a compressive force on the first ceramic material. A ceramic material of the second ceramic component can include a different coefficient of thermal expansion than a ceramic material of the first ceramic component. Optionally, a ceramic construct can include a ceramic component and a membrane disposed onto and bonded to at least a portion of the ceramic component, the membrane configured to provide fracture reinforcement to the ceramic component.
    Type: Application
    Filed: April 22, 2013
    Publication date: October 24, 2013
    Applicant: Zimmer, Inc.
    Inventors: Matthew E. Monaghan, David M. Miller
  • Patent number: 8556972
    Abstract: A monolithic material including a first region having a first variability of strength and a second region joined to the first region, the second region having a second variability of strength, wherein the monolithic material has a variability of strength less than the first variability of strength of the first region and less than the second variability of strength of the second region.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: October 15, 2013
    Assignee: Sevika Holding AG
    Inventors: Jeffrey D. Gordon, Michael G. Fisher, Paul R. Johnson, Kenneth D. Johannaber
  • Patent number: 8556987
    Abstract: A coating of blue-black or black zirconium of uniform and controlled thickness on a zirconium or zirconium alloy material is accomplished through the treatment of an amorphous zirconium or zirconium alloy substrate, which may have an altered surface roughness. The treatment of amorphous zirconium or zirconium alloy substrates includes oxidation of the substrates. A zirconium coating of uniform and controlled thickness is especially useful in various applications because the uniformly thick zirconium surface of controlled depth provide a barrier against implant corrosion caused by ionization of the metal substrates.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: October 15, 2013
    Assignee: Smith & Nephew, Inc.
    Inventors: Gordon Hunter, Shilesh C. Jani, Vivek Pawar
  • Patent number: 8529933
    Abstract: This invention relates to biomineral-based cements incorporating biopolymer carriers for the site specific introduction of natural or synthetic compounds that influence bone repair and/or patient recovery. The invention further relates to methods for producing such biphasic calcium phosphate cements for drug delivery.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: September 10, 2013
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Brian G. Amsden, Monica Y. Garcia, Ian D. Grant, Jeffrey L. Scifert, Timothy J. N. Smith
  • Publication number: 20130226310
    Abstract: This invention provides a method for producing bioactive coral bone graft substitutes and to products obtained thereby.
    Type: Application
    Filed: September 22, 2011
    Publication date: August 29, 2013
    Applicants: COREBONE LTD., RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Ohad Schwartz, Itzhak Binderman
  • Publication number: 20130190890
    Abstract: The present invention provides, among other things, multilayer film coating compositions, coated substrates and methods thereof. In some embodiments, a structure includes a first and second layer-by-layer film disposes on a substrate, the structure being characterized in that layer-by-layer removal of at least the second film releases at least one polypeptide, and also may permit release of ions from the ceramic material so that a synergetic effect of the osteoinduction and osteoconduction of the structure is achieved.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 25, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: Massachusetts Institute of Technology
  • Patent number: 8481065
    Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: July 9, 2013
    Assignee: Howmedica Osteonics Corp.
    Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
  • Patent number: 8470040
    Abstract: Implant devices for implantation within an intervertebral space are provided, together with methods and tools for use therewith. Implant devices of the present invention include an implant body formed of a synthetic bone substitute material, such as a nanocrystalline calcium phosphate material. The implant body and the methods and tools used therewith are configured to optimize strength and stability of the implant, minimize areas of stress concentration in the implant body and promote bone growth through the implant body and fusion of the vertebra.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: June 25, 2013
    Assignee: Pioneer Surgical Technology, Inc.
    Inventors: John Kovarik, Allison Rogers, Katie S. Barron, Adam MacMillan
  • Patent number: 8449622
    Abstract: An osteochondral implantable device is provided, comprising an upper cap and at least one insert comprising a non-polymeric material in physical contact with the upper cap, said lower insert comprising at least one non-polymeric material, wherein the porosity of the upper cap is greater than the porosity of the insert and the Young's modulus of the upper cap is smaller than the Young's modulus of the insert.
    Type: Grant
    Filed: September 11, 2006
    Date of Patent: May 28, 2013
    Assignee: Warsaw Orthopedic, Inc.
    Inventor: William F. McKay
  • Patent number: 8449991
    Abstract: Polycrystalline diamond compacts for use in artificial joints achieve reduced corrosion and improved biocompatibility through the use of solvent metal formulations containing tin and through the control of solvent metal pore size, particularly in inner layers of the compact. Solvent metal formulations containing tin have been discovered which provide sintering ability, part strength, and grind resistance comparable to levels achieved by using CoCrMo solvent metals. It has been discovered that limiting the solvent metal pore size in the diamond layers minimizes or eliminates the occurrence of micro cracks in the solvent metal and significantly reduces the corrosion of the compact as manifested by the release of heavy metal ions from the compact. Polycrystalline diamond compacts which utilize both the solvent metal formulations containing tin and the control of pore sizes achieve significantly reduced corrosion and improved biocompatibility compared to prior art polycrystalline diamond compacts.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: May 28, 2013
    Assignee: Dimicron, Inc.
    Inventors: Clayton F. Gardinier, Alfred S. Despres, Troy J. Medford, Tim Bunton
  • Patent number: 8439975
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 14, 2013
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Patent number: 8435306
    Abstract: An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: May 7, 2013
    Assignee: Kensey Nash BVF Technology LLC
    Inventors: Douglas G Evans, Scott M. Goldman, Russell T. Kronengold
  • Patent number: 8425619
    Abstract: An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: April 23, 2013
    Assignee: Kensey Nash BVF Technology, LLC
    Inventors: Douglas G Evans, Scott M. Goldman, Russell T. Kronengold
  • Patent number: 8425694
    Abstract: A process for producing a ceramic implant which is structured on the surface at least in the region in contact with bone and/or tissue is described. The process is characterized in that the ceramic implant after shaping and sintering is, in the region to be structured, I. reduced to the corresponding metal on the surface; II. the essentially metallic surface is subsequently subjected to a structuring surface treatment; III. the structure surface is oxidized. Furthermore, implants which have been provided with a topological structure on the surface by means of this process are described.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: April 23, 2013
    Assignee: Thommen Medical AG
    Inventors: Luis Alfonso Ortega Cruz, Falko Schlottig
  • Publication number: 20130096693
    Abstract: The invention reduces wear in total joint articulations by modifications of the shape of either component of the kinematic pair, so as to result in an annular surface contact between the two components. Fluid trapped between the two components within the inner contour of the annular contact area is pressurized under load due to elastic deformation of the components and exuded out through inter-articular gap over the surface of contact, aiding in lubrication and reducing the wear. Reduced to practice for a total hip joint with UHMWPE-metal pair, the wear rate tested in a hip joint simulator up to five million cycles was reduced by factor seven to fifteen compared to conventionally shaped components.
    Type: Application
    Filed: October 31, 2012
    Publication date: April 18, 2013
    Applicant: SCYON ORTHOPAEDICS AG
    Inventor: SCYON ORTHOPAEDICS AG
  • Patent number: 8419802
    Abstract: An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be “matched” to provide the implant with similar physical and/or chemical properties as the host tissue.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: April 16, 2013
    Assignee: Kensey Nash BVF Technology, LLC
    Inventors: Douglas G Evans, Scott M. Goldman, Russell T. Kronengold
  • Patent number: 8415019
    Abstract: A new composition and medical implant made there from comprises a thick diffusion hardened zone, and layered ceramic surface. Orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition are disclosed.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: April 9, 2013
    Assignee: Smith & Nephew, Inc.
    Inventors: Vivek Devidas Pawar, Shilesh C. Jani, Carolyn L. Weaver
  • Patent number: 8414654
    Abstract: An implant device for humans or mammals has a body structure having an exposed surface and one or more selected portions of the exposed surface having a bone formation enhancing 3-dimensional pattern. The exposed surface can be on exterior portions of the body structure or internal portions of the body structure or both. The one or more selected portions of the exposed portions having the bone formation enhancing 3-dimensional patterns are in the external exposed surfaces or in the internal exposed surfaces or both internal and external exposed surfaces.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: April 9, 2013
    Assignee: Amendia, Inc.
    Inventor: Timothy Ganey
  • Publication number: 20130041475
    Abstract: Disclosed are a gradient bioceramic coating comprising a rare earth oxide, a broadband laser method for preparing the bioceramic coating, and the use of the bioceramic coating in the field of medical materials.
    Type: Application
    Filed: June 26, 2012
    Publication date: February 14, 2013
    Applicant: GUIZHOU UNIVERSITY
    Inventors: Qibin Liu, Wenfei Li, Ling Wu
  • Patent number: 8353967
    Abstract: A biocompatible, self-supporting, curved, collagen membrane adapted to be secured by bone tacks or bone screws over exposed bone at a desired bone graft site in the alveolar ridge of a patient such that the membrane defines a space having a predetermined height and width over the exposed bone, in which the membrane maintains its structural integrity for at least 4 months after implantation at the bone graft site and then naturally breaks down and is resorbed by the patient's body, a method of making such a membrane, and a method of using such a membrane for vertical augmentation of the alveolar ridge of the patient.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: January 15, 2013
    Assignee: Osseous Technologies of America
    Inventors: Jay Malmquist, David Cheung, William Knox
  • Publication number: 20120310365
    Abstract: A cranial implant designed to fill a cranial defect of the skull of a mammal or a human, wherein the cranial implant is made of biocompatible ceramic and includes an implant body having a shape and size substantially matching the shape and size of the cranial defect to be filled, wherein the implant body includes an outer face facing outside the skull and an inner face facing inside the skull when the implant disposed on the skull, characterized in that the implant includes one or more reinforcing members protruding from the inner face of the implant body. A method of manufacturing the cranial implant is also described.
    Type: Application
    Filed: May 18, 2012
    Publication date: December 6, 2012
    Applicant: 3DCERAM
    Inventors: Christophe CHAPUT, Richard GAIGNON, Joël BRIE