Abstract: Disclosed is an intraocular lens assembly provided inside a capsular sac. The intraocular lens assembly according to one embodiment of the present invention includes an intraocular lens and an intraocular lens supporter, and therefore the intraocular lens assembly may be useful to transfer a force to the intraocular lens, inserted inwardly into the capsular sac, to allow the intraocular lens to move like a natural eye lens, the force being generated from the ciliaris muscle and transferred through the zonule of Zinn and the capsular sac.

Abstract: A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.

Abstract: Provided herein are a devices, ophthalmic lens systems and methods for restoring natural tension and anatomy of a lens capsule post-surgically in an eye of a subject. The device generally comprises an inward tensioning ring-like structure having a shape configured to circumferentially fit within and be anchored to a post-surgical lens capsule of the eye. The device may have one or both of external and internal grooves formed to receive the lens capsule and one or both of an intraoptical lens or a tensioning element. The ophthalmic lens system generally comprises the device and an intraocular lens inserted therein. The anchored device provides tension to an equatorial area of the capsule resulting in a decrease in equatorial diameter.

Abstract: The present application describes a device and methods that use a small-aperture mask surgically implanted in the optical path to improve the depth of focus of, for example, a pseudophakic patient. The device can be inserted adjacent to an intraocular lens (IOL). The device may include one or more connectors for attaching the device to an intraocular lens.

Abstract: A foldable intraocular lens for providing vision contains an optic body that includes an optical zone and a peripheral zone entirely surrounding the optical zone. The optic body has an anterior face, a substantially opposing posterior face, an optic edge, and an optical axis. The anterior face comprises a central face, a peripheral face, and a recessed annular face therebetween that is disposed posterior to the peripheral face. The intraocular lens further comprises at least one haptic that is integrally formed with the peripheral zone. The haptic comprises a distal posterior face, a proximal posterior face, and a step edge disposed at a boundary therebetween. The haptic further comprises a side edge disposed between the optic edge and the step edge. The proximal posterior face and the posterior face of the optic body form a continuous surface. An edge corner is formed by the intersection of the continuous surface with the optic edge, the side edge, and the step edge.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: The invention is directed to a lens that comprises an optic and at least two haptic rings, one positioned to rest against the posterior capsule distally outward from the optic zone, the other to rest on the anterior capsule some distance from the equator. The haptic rings of the lens are connected by segments of haptic material that may be arched or straight, and sections of open space to provide for ample circulation of the aqueous humor. The optic is suspended between the two haptic rings such that the distance between the optic and the anterior ring is constant while the distance between the optic and the posterior ring may vary according to the overall capsular dimensions of the eye of the patient.

Abstract: An accommodating intraocular lens, for use in an eye, is made from flexible, optionally elastic, bio-compatible lens body material surrounding a closed and sealed lens cavity. One or more compressible struts is in the cavity. The cavity is filled with bio-compatible optical liquid. The optical liquid has a refractive index sufficiently high to, in cooperation with the ciliary muscle and the compressible strut, focus light, incident on the eye, on the retina, thus to provide accommodation. The curvature of the surface of the lens is deformable, by the forces expressed by the ciliary body and the strut, thus to change the radius of curvature of the anterior body member and/or the posterior body member, thus providing focusing, including from relatively farther distance in the relaxed state to relatively nearer distance in the accommodative state.

Abstract: An accommodating intraocular lens for providing a range of accommodative vision contains an optic and a haptic. The optic is disposed about an optical axis and includes an anterior surface and a posterior surface defining a clear aperture of the optic. The haptic is at least partially disposed inside the optic and includes an inner structure, an outer structure, and a plurality of arms disposed between and connecting the inner structure and the outer structure. The inner structure is circumferentially disposed about the optical axis, while the outer structure is circumferentially disposed about the inner structure and has an outer face. Each arm has proximal portion adjacent the inner structure and a distal portion adjacent the outer structure that is bifurcated in a radial direction from the proximal portion. The intraocular lens also has an outer surface defined by outer surfaces of the plurality of arms and an outer surface of the outer structure.

Abstract: An intraocular lens comprises an optic portion having a peripheral edge and at least two haptics. Each haptic is integrated with the peripheral edge of the optic portion by a corresponding haptic integration region. Also, each haptic comprises a distal segment region and a deformation segment region. The distal segment region has an outer distal length bounded by a proximate endpoint and a distal endpoint on an outer surface of the haptic, and is scribed by a distal segment angle ? of 20° to 30°. The distal segment angle has a segment origin that lies within a radial segment bound by a radial distance 1.5 mm to 1.9 mm from an optic center and a segment angle ? of from 30° to 45° from a vertical axis. The vertical axis extends through the distal endpoint of at least one haptic and the optic center.

Abstract: Accommodating intraocular lens (AIOL) assemblies including a discrete pre-assembled monolithic AIOL assemblage and a discrete haptics system having a haptics ring and at least two elongated C-shaped haptics for self-anchoring in a human scleral wall at the ciliary sulcus. The AIOL assemblages include an AIOL capsule and an integrally formed base member. The AIOL assemblages also include an annular haptics support surround posterior to an anterior structure on implantation in a human eye of a supine human. AIOL assemblies are assembled in situ by mounting a haptics system onto a previously implanted AIOL assemblage. The haptics system bears against the annular haptics support surround. The anterior structure is freely telescopically received in the haptics ring.

Abstract: An intraocular lens comprising: (a) monomeric units derived from at least one cationically polymerizable branched alkene monomer; (b) monomeric units derived from at least one cationically polymerizable monomer having a pendant benzocyclobutene group; and (c) a UV-absorbing benzotriazole component having the formula I.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: Accommodating intraocular lenses containing a flowable media and their methods of accommodation.

Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.

Abstract: An improved intraocular lens, for example, an accommodating intraocular lens including a lens optic or lens optic portion provided with a light window.

Abstract: An intraocular lens assembly for implantation in the posterior chamber of an eye has anchor portions with teeth rigid enough to penetrate the scleral wall of an eye. A method for implanting the lens includes the steps of: introducing the first haptic portion with a first anchor portion that includes a plurality of teeth projecting therefrom, into the posterior chamber of the eye until said teeth are anchored in the scleral wall at a desired location; and moving a second haptic portion with a plurality of teeth projecting therefrom, until said teeth are anchored in the scleral wall on the opposite side of the lens from the first anchor portion.

Abstract: An intraocular lens (IOL) assembly for correcting myopia, hyperopia and astigmatism is provided. The intraocular lens assembly comprises a lens extending along an optical axis between an anterior optical surface and a posterior optical surface. The IOL has a circumferential edge disposed about the optical axis at a junction of anterior and posterior optical surfaces with N haptics, where N is an integer greater than 1. Each haptic extends from an associated portion of the circumferential edge and along an associated haptic axis and extends between end portions joined to the lens at the circumferential edge. Each of the haptics includes M footplates extending symmetrically about its associated haptic axis, where M may be an integer greater than 0. The resultant vaulted structure provides an intraocular lens assembly that, when implanted in the eye, allows accommodation.

Abstract: An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The haptic may be pre-stressed before the optic is placed within it. After such placement, the pre-stress may be relieved, and the haptic may produce stress in the optic. The pre-stress may produce a radial tension or a radial compression in the optic. Alternatively, once the optic is placed within the haptic, both may undergo a process that changes the size and/or shape of one with respect to the other, causing a stress within the optic. This process may produce a radial tension or a radial compression in the optic. The haptic may include an annular ring having outer and inner diameters that may depend on the stiffness of the haptic.

Abstract: The present invention provides copolymers made up of alkoxyalkyl methacrylate and/or alkoxyalkyl acrylate monomers in combination with one or more additional hydrophobic monomers. The copolymers may be used in the manufacture of intraocular lenses, including both the optic and haptic portions of the lenses. The present invention also provide methods for making intraocular lenses from the copolymers.

Abstract: A method of maintaining the structure of an opening in the anterior or posterior capsule formed by a capsulorhexis whereby a device is inserted into opening in the anterior or posterior capsule, the device having a main body including a peripheral portion and an opening therethrough, wherein the peripheral portion engages with the inside peripheral edge of the opening in the anterior or posterior capsule, wherein the device is inserted into the opening in the anterior or posterior capsule after an intraocular lens has been inserted into the capsular bag of an eye during cataract corrective surgery.

Abstract: An intraocular lens for insertion into the capsular bag of an eye contains an optic, an outer periphery, and an outer support structure. The optic has a periphery and centered about an optical axis. The outer periphery is disposed about the optic and configured to engage an equatorial region of the capsular bag of an eye. The outer support structure is disposed along the periphery and spaced from the optic with voids outer support structure and the optic. The intraocular lens further comprises a first intermediate member and a weakened region disposed along the outer periphery between the outer support structure and the first intermediate member. The first intermediate member operably couples the optic and the outer support structure. The weakened region is attached to, and configured to provide relative motion between, the outer support structure and the first intermediate member in response to the ciliary muscle of the eye.

Abstract: A haptic for fixation to, and manufacture in conjunction with, an intraocular lens to be implanted in the natural lens capsule of the human eye is disclosed. The haptic secures the lens in an appropriate position within the natural capsule so as to provide optimal visual acuity through the aphakic lens. The haptic ends are designed to position the lens neutrally, anteriorly or posteriorly within the lens envelope. The haptic has a of an anterior retention ring and a posterior retention ring.

Abstract: An intraocular lens fixation device including a deformable, medically inert clip that affixes a haptic of an intraocular lens to a patient's iris. A method of affixing an intraocular lens, having haptics, within a patient's eye includes piercing the iris in at least two locations that closely flank a portion of one of the haptics, inserting an arm of a biologically inert deformable clip through each of the piercings in the iris until a distal end of each arm is located on opposing sides of the haptic, and applying a force to each of the arms to deploy the clip by causing the distal ends of the arms to approach each other and substantially surround and constrain both a section of the iris that is between the arms and a portion of the haptic.

Abstract: The invention is directed to a lens that comprises an optic and two haptic rings, one positioned to rest against the posterior capsule distally outward from the optic zone, the other to rest on the anterior capsule some distance from the equator. The haptic rings of the lens are connected by segments of haptic material that may be arched or straight, and sections of open space to provide for ample circulation of the aqueous humor. The optic is positioned against the posterior capsule as close as possible to the nodal zone of the eye.

Abstract: An anterior chamber phakic lens made from a foldable, highly biocompatible material that has a very low haptic compression force and low axial displacement, yet is stable in the anterior chamber.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.

Abstract: A haptic is provided for use in an accommodating intraocular lens. The haptic has multiple filaments, each connected to the edge of the optic at one end. Each filament has a shape that conforms to an equatorial region of the capsular bag. The haptic couples the forces exerted by the capsular bag of the eye during accommodation radially to the edge of the optic, produce a diametric expansion or compression of the optic. This diametric motion distorts the optic, producing a change in any or all of the anterior radius, the posterior radius, and the thickness. These changes affect the power of the lens and/or location of the image. The haptic may optionally have a thin membrane joining the filaments at the optic end, and may optionally have a connecting ring that joins the filaments at the end opposite that of the optic.

Abstract: The present invention relates to an accommodating intraocular lens, which is suitable for replacement of the natural crystalline lens of the eye within the capsular bag. The intraocular lens can include a retainer plate with an annular region surrounding a central opening, and an optical lens. The retainer plate acts as a foundation for the optical lens, as the retainer plate can be positioned near or at the posterior portion of the lens capsule. The optical lens can sit on the retainer plate, but is otherwise not attached to the retainer plate. The optical lens can overlap or fit within the central opening of the retainer plate. The retainer plate can include a lip portion integrally disposed on a region of the retainer plate, wherein the lip provides a surface for holding at least a portion of an intraocular lens.

Abstract: An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition.

Abstract: An intraocular lens (31) which may be used as a posterior lens in a lens train including a converging anterior lens (20) and diverging posterior lens (31) in which the optical/focal axes of the two lenses are not coincident such that the focal point (9) of the lens train is offset from the focal axis of the anterior lens. Light rays (50) incident upon the anterior lens parallel to its focal axis may thus be directed (51) to parts of the retina offset from the fovea where the macula may not have degenerated.

Abstract: An intraocular lens comprises an optic and at least two haptics, each of which comprises a step feature that protrudes from a posterior surface of the haptic to prevent posterior capsular opacification.

Abstract: An intraocular lens comprises an optic and at least two haptics. Each haptic is offset in an anterior direction from a central optic plane of the optic. The offset allows for predictable posterior vaulting upon implantation.

Abstract: A vision correction system comprising an intraocular lens having a lens body and one or more haptics is provided. The lens body may be configured to be positioned posteriorly to an iris of an eye and may have a convex anterior surface, a concave posterior surface, and a circumferential edge having a rounded anterior portion and a rounded posterior portion. Haptics may extend at an anterior angle from the lens body and be configured to contact the ciliary sulcus of an eye. The haptics may secure the intraocular lens in the eye in a relatively fixed position and prevent rotation of the lens over time.

Abstract: An ocular lens has a refractive optics structure formed from a polyisobutylene-based material and a glassy segment that is non-reactive to ocular fluid and that maintains in vivo transparency for a substantial time period. The material has a central elastomeric polyolefinic block and thermoplastic end blocks (such as a triblock polymer backbone comprising polystyrene-polyisobutylene-polystyrene). The material is preferably flexible such that the refractive optics structure can be folded upon itself and introduced through a small scleral incision. The lens device includes an optic portion and preferably either an annular haptic element or one or more haptic elements adapted to rest within a capsular bag formed by a surgical procedure. A portion of the lens device may be loaded with at least one therapeutic agent that interferes with proliferation of the epithelial cells of the eye to protect against PCO.

Abstract: An intraocular lens assembly for implantation in the posterior chamber of an eye has anchor portions with teeth rigid enough to penetrate the scleral wall of an eye. A method for implanting the lens includes the steps of: introducing the first haptic portion with a first anchor portion that includes a plurality of teeth projecting therefrom, into the posterior chamber of the eye until said teeth are anchored in the scleral wall at a desired location; and moving a second haptic portion with a plurality of teeth projecting therefrom, until said teeth are anchored in the scleral wall on the opposite side of the lens from the first anchor portion.

Abstract: An injectable intraocular implant including an optics portion and a resilient, flexible haptics portion mounted coaxially with the optics portion and a method for inserting the implant into the eye.

Abstract: Intraocular rings, intraocular lens systems, and associated methods are disclosed. In some instances, the intraocular rings are formed of biocompatible pharmaceutical delivering materials and are configured to be implanted with conventional intraocular lens designs. The intraocular rings include engagement features for interfacing with haptics of the conventional intraocular lens designs in order to ensure proper orientation of the intraocular ring and intraocular lens relative to one another. In some instances, the intraocular rings also include haptics to encourage centering of the intraocular ring within the posterior capsule. The intraocular rings also serve to prevent posterior capsular opacification.

Abstract: The invention is directed to an assembly comprising a haptic for fixation to, and manufacture in conjunction with, an intraocular lens to be implanted in the natural lens capsule of an eye. The haptic of the invention comprises a continuous ribbon forming an essentially oblong shape having anterior and posterior portions relative to the elliptical center of the haptic, wherein the ribbon loop includes two or more essentially congruent ribbon arches in each portion, and each ribbon arch has a natural index of curvature with an inner and outer edges. designed to expand the eye capsule and put tension on the zonules of the eye. The ribbon affixes to the lens on each side of the optic edge at a point or a series of points that provides suitable centration and stability of the optic, and to suspend the optic in the open capsular space.

Abstract: The invention is directed to an assembly comprising a haptic for fixation to, and manufacture in conjunction with, an intraocular lens to be implanted in the natural lens capsule of an eye. The haptic of the invention comprises a continuous ribbon forming an essentially oblong shape having anterior and posterior portions relative to the elliptical center of the haptic, wherein the ribbon loop includes two or more essentially congruent ribbon arches in each portion, and each ribbon arch has a natural index of curvature with an inner and outer edges. designed to expand the eye capsule and put tension on the zonules of the eye. The ribbon affixes to the lens on each side of the optic edge at a point or a series of points that provides suitable centration and stability of the optic, and to suspend the optic in the open capsular space.

Abstract: The present invention provides an accommodative intraocular lens (AIOL) system and method for improving accommodation with an intraocular lens. The method involves insertion into the capsular bag of a flexible optic holder comprising a plurality of haptics configured to allow the capsular bag to be sectioned at regular intervals following fusion of the capsular bag. The haptics of the optic holder are designed to allow maximum fusion of the anterior and posterior leaves of the capsular bag following placement of the optic holder in the capsular bag. Following introduction of the optic holder into the capsular bag, the natural or assisted process of fibrosis/fusion of the capsular bag occurs, thereby sealing and securely capturing the haptics within the capsular bag.

Abstract: An intraocular optic assembly including an anterior haptic member and a posterior haptic member arranged to correspond to anterior and posterior portions of a capsular bag, respectively, having an anterior-posterior axis passing centrally through the anterior and posterior haptic members, bendable link members attached to and between the anterior and posterior haptic members, an optic, and a lever pivotally connected at on end thereof to a first attachment point on a periphery of the optic and connected at an opposite end thereof to a second attachment point on one of the bendable link members, wherein linear movement of one of the anterior and posterior haptic members along the anterior-posterior axis applies a lever force on the optic with the lever that causes the optic to move linearly along the anterior-posterior axis.

Abstract: Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: A multi-component intraocular lens implanted in an optical system of a human eye includes one or more removable components, each component being foldable. One component acts as a base lens, including a flange with an aperture. Another component acts as a mid lens, including a tab which engages the aperture. A third component acts as a top lens, which engages the mid lens. Because the lens components are foldable, they may be inserted into the eye using an incision smaller than the diameter of the unfolded lens. The removable components may be used to correct various medical conditions of the eye, as well as to improve and enhance vision, and for cosmetic purposes.

Abstract: The present invention discloses a multi-component intraocular lens implanted in an optical system of a human eye, including one or more foldable removable components, each component being foldable. One component acts as a base lens, including a flange with a slot. Another component acts is an optical assembly that may include a top lens joined to or integrated with a mid lens. The top lens, the mid lens or the optical assembly may include at least one projection that engages the slot of the base lens. The top and mid lenses are manufactured from a material having adhesive properties, wherein the top and mid lenses adhere to each other free of any material or substance being present therebetween.

Abstract: Accommodating intraocular lenses containing a flowable media and their methods of accommodation.

Abstract: Accommodating intraocular lenses containing a flowable media and their methods of accommodation.

Abstract: An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.

Abstract: An intraocular lens implant includes a lens having an anterior portion, a posterior portion, and a circumferential edge located therebetween. An annular notch is formed in the anterior portion and oriented in an anteriorly-directed orientation.