Method Of Manufacturing Prosthetic Device Patents (Class 623/901)
  • Patent number: 10380792
    Abstract: Examples associated with three-dimensional model generation are disclosed. One example includes analyzing a structure of a first component of an object. The composition of the first component of the object is also analyzed. A three-dimensional model of the object is then generated. The three-dimensional model includes data based on the structure of the first component of the object and data based on the composition of the first component of the object.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: August 13, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Jack Hui He, Paul Howard Mazurkiewicz, Hang-Yan Yuen
  • Patent number: 9901404
    Abstract: Disclosed herein is a surgical guide tool for use in total hip replacement surgery. The surgical guide tool may include a customized mating region and a resection guide. The customized mating region and the resection guide are referenced to each other such that, when the customized mating region matingly engages a surface area of a proximal femur, the resection guide will be aligned to guide a resectioning of the proximal femur along a preoperatively planned resection plane.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: February 27, 2018
    Assignee: Howmedica Ostenoics Corporation
    Inventors: Ilwhan Park, Michael Koehle, Lorenzo R. Deveza
  • Patent number: 9827717
    Abstract: A non-transitory, tangible, computer-readable storage media may contain a program of instructions that causes a computer system having a processor running the program of instructions to: receive design information indicative of the design of a three-dimensional object to be printed by a three-dimensional printer; receive test product deformation information indicative of deformation in the profiles of no more than five, three-dimensional test products that have a circular or polygonal cross section that were made by the three-dimensional printer; generate polygon product deformation information indicative of a predicted deformation of a polygon shape that the three-dimensional printer will print and that has a number of sides and a number of sizes that are both different from each of the number of sides and number of sizes that the no more than five, three-dimensional test products have; and generate adjustment information indicative of an adjustment needed to print a desired profile of the polygon shape that
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: November 28, 2017
    Assignees: University of Southern California, President and Fellows of Harvard College
    Inventors: Qiang Huang, Tirthankar Dasgupta, Sobambo Sosina
  • Patent number: 9737392
    Abstract: In a method and system for producing an implant, the latter is designed with one or more surfaces extending in the longitudinal direction of the implant. Two or three production stages can be used. In one stage, either a topography with a long wave pattern is produced by means of cutting work, or laser bombardment or further cutting work is used to produce a topography with an intermediate-length wave pattern. In addition, an oxidation process or shot-peening or etching is used to produce an outer layer. When using two of said production stages, said cutting work or said laser bombardment or further cutting work is followed by the oxidation process or the shot-peening or etching method. When using all three production stages, cutting work is followed by laser bombardment, or further cutting work, which in turn is followed for example by the oxidation process. The invention also relates to an implant which is produced using the method and is identified, ordered and produced using the system.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: August 22, 2017
    Assignee: Nobel Biocare Services AG
    Inventor: Jan Hall
  • Patent number: 9675272
    Abstract: Methods, systems, and devices are provided for guiding surgical instruments using radio frequency (RF) technology. In general, the methods, systems, and devices can allow a trajectory, e.g., an angular approach, of a surgical instrument relative to a patient to be identified during use of the instrument in a surgical procedure being performed on the patient. The trajectory can be identified using a plurality of RF modules. The methods, systems, and devices can allow the trajectory to be compared to a predetermined trajectory so as to identify whether the trajectory matches the predetermined trajectory. A result of the matching can be communicated to a user of the instrument. Based on the result, the user can maintain the trajectory, e.g., if the trajectory matches the predetermined trajectory, or can adjust the trajectory to closer align the trajectory with the predetermined trajectory, e.g., if the trajectory does not match the predetermined trajectory.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: June 13, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Sean P. Selover, Joseph Hernandez, John Riley Hawkins, John Dieselman, John Paul Griffin, Jennifer DiPietro
  • Patent number: 9034005
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: May 19, 2015
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Patent number: 9034358
    Abstract: The present invention provides methods of improving the osteogenic and/or chondrogenic activity of a bone matrix, e.g., a dermineralized bone matrix (DBM), by exposing the bone matrix to one or more treatments or conditions. In preferred embodiments the bone matrix is derived from human bone. The treatment or condition may alter the structure of the bone matrix and/or cleave one or more specific proteins. Cleavage may generate peptides or protein fragments that have osteoinductive, osteogenic, or chondrogenic activity. Preferred treatments include collagenase and various other proteases. The invention further provides improved bone and cartilage matrix compositions that have been prepared according to the inventive methods and methods of treatment using the compositions. The invention further provides methods of preparing, testing, and using the improved bone matrix compositions.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: May 19, 2015
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Keyvan Behnam, Christopher Cioffi
  • Patent number: 9011518
    Abstract: A stent for placement in a body lumen is fabricated by forming a tube having an un-deployed diameter sized for the tube to be placed on a deployment balloon and advanced through a body lumen to a deployment site. The tube is expandable upon inflation of the balloon to an enlarged diameter sized for the tube to be retained within the lumen at the site upon deflation and withdrawal of the balloon. The tube has a stent axis extending between first and second axial ends of the tube. The tube has an exterior surface and an interior surface. The tube is polished to polish the exterior surface to a smooth surface finish and with at least a portion of the interior surface having a rough surface finish rougher than the surface finish of the exterior surface.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: April 21, 2015
    Assignee: Covidien LP
    Inventor: Paul J. Thompson
  • Patent number: 9011553
    Abstract: A flexible laminate formed from at least a first layer comprising a first flexible elastomer and a second layer comprising a second flexible elastomer, which are connected to one another by an intermediate layer. The intermediate layer comprises parylene and is applied to the first layer such that the intermediate layer has an irregular surface with irregularities. The second flexible elastomer or an adhesive connected to the second layer is applied in liquid form to the intermediate layer such that the irregularities the intermediate layer are at least partially filled.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: April 21, 2015
    Assignee: Otto Bock Healthcare GmbH
    Inventor: Dionys Dornieden
  • Patent number: 8979936
    Abstract: An orthopedic implant includes a first portion including at least one feature modified to be patient-specific and match the anatomy of a specific patient from a three-dimensional digital image of a patient's joint using computer modeling. The orthopedic implant includes a non-custom inner bone-engaging surface including a plurality of planar surfaces configured for engagement with non-custom bone cuts.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: March 17, 2015
    Assignee: Biomet Manufacturing, LLC
    Inventors: John R. White, Robert Metzger, Keith R. Berend
  • Patent number: 8974517
    Abstract: A radiopaque nitinol stent for implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element including tungsten. The added tungsten in specified amounts improve the radiopacity of the nitinol stent comparable to that of a stainless steel stent of the same strut pattern coated with a thin layer of gold. Furthermore, the nitinol stent has improved radiopacity yet retains its superelastic and shape memory behavior and further maintains a thin strut/wall thickness for high flexibility.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: March 10, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Brian Lee Pelton, John F. Boylan
  • Patent number: 8961529
    Abstract: A replacement device for resurfacing a joint surface of a femur and a method of making and installing such a device is provided. The custom replacement device is designed to substantially fit the trochlear groove surface, of an individual femur, thereby creating a “customized” replacement device for that individual femur and maintaining the original kinematics of the joint. The top surface is designed so as to maintain centrally directed tracking of the patella perpendicular to the plane established by the distal end of the femoral condyles and aligned with the center of the femoral head.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: February 24, 2015
    Assignee: Kinamed, Inc.
    Inventors: Roger Carignan, Clyde R. Pratt
  • Patent number: 8936602
    Abstract: A replacement device for resurfacing a joint surface of a femur and a method of making and installing such a device is provided. The custom replacement device is designed to substantially fit the trochlear groove surface, of an individual femur, thereby creating a “customized” replacement device for that individual femur and maintaining the original kinematics of the joint. The top surface is designed so as to maintain centrally directed tracking of the patella perpendicular to the plane established by the distal end of the femoral condyles and aligned with the center of the femoral head.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 20, 2015
    Assignee: Kinamed, Inc.
    Inventors: Roger Carignan, Clyde R. Pratt
  • Patent number: 8936601
    Abstract: A replacement device for resurfacing a joint surface of a femur and a method of making and installing such a device is provided. The custom replacement device is designed to substantially fit the trochlear groove surface, of an individual femur, thereby creating a “customized” replacement device for that individual femur and maintaining the original kinematics of the joint. The top surface is designed so as to maintain centrally directed tracking of the patella perpendicular to the plane established by the distal end of the femoral condyles and aligned with the center of the femoral head.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: January 20, 2015
    Assignee: Kinamed, Inc.
    Inventors: Roger Carignan, Clyde R. Pratt
  • Patent number: 8882822
    Abstract: Disclosed is the use of serous tissue, such as pericardium, as a component of intracorporeal implants. Particularly, disclosed is a jacketed stent assembly comprising an expandable stent provided with a jacket of processed serous tissue which, in some embodiments, is impregnated with a therapeutic or diagnostic agent. In a preferred embodiment, the jacket of the expandable stent is formed of pericardial tissue, preferably bovine or porcine pericardial tissue.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: November 11, 2014
    Assignee: Design & Performance-Cyprus Limited
    Inventor: Carlos Vonderwalde
  • Patent number: 8864815
    Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film. The cover may include one or more filaments, e.g., wires, which cooperate with the film to provide desirable mechanical properties. The wires may be integrated with the film by depositing the film over the wires.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: October 21, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Masoud Molaei, Beren W. Correa
  • Patent number: 8858207
    Abstract: In one embodiment, a method for treating an infected implant area of a knee joint comprises surgically accessing the implant area, and inserting a tibial component into the tibia using an antibiotic-impregnated material. A femoral component is formed that is configured to interact with the tibial component by stable knee joint articulation and motion. The femoral component is formed of an antibiotic-impregnated material using a mold. The femoral component is attached to the femur using an antibiotic-impregnated material, and the tibial component is interfaced with the femoral component to form a stable temporary knee joint capable of reducing the spread of infection while permitting movement of the knee joint.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: October 14, 2014
    Inventor: Richard Parker Evans
  • Patent number: 8852580
    Abstract: An implant for repair of a cartilaginous defect in a subject includes a collagen matrix charged with synovial cells. A method preparing an implant for repair of a cartilaginous defect in a subject includes obtaining a fluid containing synovial cells and charging the synovial cells to the matrix. A device for preparing a cell-charged implant includes a first chamber and a second chamber, the first and second chambers being separated by a membrane and a perforated filter. The membrane is adapted to collect cells from a cell-containing fluid introduced into the first chamber and the perforated filter is adapted to permit passage or diffusion of the fluid through the second chamber. A method for preparing a cell-charged implant utilizes the device.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: October 7, 2014
    Assignee: Geistlich Pharma AG
    Inventors: Birgit Schaefer, Lothar Schloesser
  • Patent number: 8771281
    Abstract: A replacement device for resurfacing a joint surface of a femur and a method of making and installing such a device is provided. The custom replacement device is designed to substantially fit the trochlear groove surface, of an individual femur. Thereby creating a “customized” replacement device for that individual femur and maintaining the original kinematics of the joint. The replacement device may be defined by four boundary points, and a first and a second surface. The first of four points is 3 to 5 mm from the point of attachment of the anterior cruciate ligament to the femur. The second point is near the bottom edge of the end of the natural articulatar cartilage. The third point is at the top ridge of the right condyle and the fourth point at the top ridge of the left condyle of the femur.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: July 8, 2014
    Assignee: Kinamed, Inc.
    Inventors: Roger Carignan, Clyde R. Pratt
  • Patent number: 8617441
    Abstract: A method for making an encapsulated stent includes providing a first seamless unsintered ePTFE tube, providing a second seamless unsintered ePTFE tube, positioning a balloon-expandable stent between the first and second ePTFE tubes to form an assembly, disposing an ePTFE interlayer member between the first and second ePTFE tubes, and joining the first ePTFE tube to the second ePTFE tube through openings in a wall of the stent by applying first pressure, and then heat, to the assembly.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: December 31, 2013
    Assignee: Bard Peripheral Vascular, Inc.
    Inventors: Tarun J. Edwin, Christopher E. Banas, Brendan Mccrea
  • Patent number: 8567162
    Abstract: The present disclosure relates to a dynamic bioactive bone graft material and a method of handling the material to prepare an implant. In one embodiment, a method of preparing a dynamic bioactive bone graft implant is provided. The method includes the step of providing a porous, fibrous composition of bioactive glass fibers, wherein the fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and wherein the porosity of the matrix ranges from about 100 nanometers to about 1 millimeter. The porous, fibrous composition is introduced into a mold tray, and a shaped implant is created using the mold tray. The composition may be wetted with a fluid such as saline or a naturally occurring body fluid like blood prior to creating the shaped implant. In another embodiment, the porous, fibrous composition is provided with the mold tray as a kit.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: October 29, 2013
    Assignee: Prosidyan, Inc.
    Inventors: Charanpreet S. Bagga, Hyun W. Bae, Thomas E. Day
  • Patent number: 8423167
    Abstract: For use in connection with evaluating prosthetic sockets (and other objects) designed and fabricated with computer aided design and manufacturing software, the shape of a socket is accurately scanned and digitized. The scanned data are then compared to either an electronic shape data file, or to the shape of another socket, a positive model of a residual limb (or socket), or a residual limb. Differences detected during the comparison can then be applied to revise the design or fabrication of the socket, to more accurately achieve a desired shape that properly fits the residual limb of a patient and can be used to solve the inverse problem by correcting for observed errors of a specific fabricator before a socket is produced. The digitizing process is implemented using a stylus ball that contacts a surface of the socket to produce data indicating the three-dimensional shape of the socket.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: April 16, 2013
    Assignee: University of Washington
    Inventors: Joan E. Sanders, Michael R. Severance, Timothy R. Myers, George Turkiyyah, Elizabeth A. Sorenson, Ellen L. Lee
  • Patent number: 8419741
    Abstract: A replacement device for resurfacing a joint surface of a femur and a method of making and installing such a device is provided. The custom replacement device is designed to substantially fit the trochlear groove surface, of an individual femur, thereby creating a “customized” replacement device for that individual femur and maintaining the original kinematics of the joint. The top surface is designed so as to maintain centrally directed tracking of the patella perpendicular to the plane established by the distal end of the femoral condyles and aligned with the center of the femoral head.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: April 16, 2013
    Assignee: Kinamed, Inc.
    Inventors: Roger Carignan, Clyde R. Pratt
  • Patent number: 8407067
    Abstract: An orthopedic device includes a femoral implant having a non-custom internal bone engagement surface. The femoral implant includes at least nine parameters adjusted preoperatively to correspond to a specific patient. The parameters can include patient-specific lengths, such as, for example, medial and lateral condyle widths and notch height, and patient-specific medial and lateral angles.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: March 26, 2013
    Assignee: Biomet Manufacturing Corp.
    Inventors: Brian A. Uthgenannt, Robert Metzger, Nathan E. Belcher, Joshua B. Catanzarite
  • Patent number: 8377073
    Abstract: The present disclosure is directed to orthopedic implants and methods of designing orthopedic implants using in vivo data specific to an orthopedic implant or orthopedic trial. Specifically, the instant disclosure utilizes permanent orthopedic implants and orthopedic trials outfitted with pressure sensors to provide feedback regarding the position and magnitude of pressures exerted upon the devices to discern which design is preferable or which designs are preferable.
    Type: Grant
    Filed: January 3, 2009
    Date of Patent: February 19, 2013
    Inventor: Ray Wasielewski
  • Patent number: 8353965
    Abstract: A technique to manufacture small joint orthopedic implants includes the steps of taking standard radiographs of a pathologic joint and the corresponding non-pathologic joint. In order to provide an accurate frame of reference, a specialized marker is placed in the radiographic field. By inspection of the radiographs and by comparison with the marker, the dimensions of the cortical bone and the cancellous bone can be quickly and accurately determined. These dimensions can be used to manufacture a suitable implant and installation tool. Typically, the implant will include a stem from which a post projects. A radially extending collar is located at the intersection between the stem and the post. A mating head is attached to the post. The head closely approximates the size and shape of the natural head being replaced. The stem will be non-round in cross-section to prevent rotation of the stem in the bone.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: January 15, 2013
    Inventors: William H. Seitz, Jr., Albert N. Santilli
  • Patent number: 8352056
    Abstract: The present invention illustrates a method of manufacturing a surgical implant guide to increase the precision, safety and reliability of the surgery. First the present invention plans an invasive position for implanting an implant, and then, plans an invasive path for the implant to invade from the invasive position of an affected tissue, and finally, produces an implant guide based on the invasive position, the invasive path, and the shapes of the implant and the affected tissue. The surgical implant guide includes a coupling portion matching the shape the affected tissue, and a guiding portion matching the shape of the implant, the invasive position, and the invasive path. When the coupling portion is disposed on the affected tissue, the guiding portion is aligned with the invasive position, so that the implant is implanted in the affected tissue under guidance of the invasive path.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: January 8, 2013
    Assignee: Chang-Gung University
    Inventors: Shih-Tsen Lee, Chieh-Tsai Wu, Heng-Liang Liu, Ming-Yuan Tsai
  • Patent number: 8343218
    Abstract: Disclosed herein are methods and compositions for producing articular repair materials and for repairing an articular surface. In particular, methods for providing articular repair systems. Also provided are articular surface repair systems designed to replace a selected area cartilage, for example, and surgical tools for repairing articular surfaces.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: January 1, 2013
    Assignee: ConforMIS, Inc.
    Inventors: Philipp Lang, Daniel Steines, Konstantinos Tsourgarakis
  • Patent number: 8216657
    Abstract: A preform for making a prosthetic limb socket includes an injection molded disk of thermoplastics material, and a peripheral portion of the disk is supported by a rigid metal ring. The ring and the peripheral disk portion have an interfitting connection which permits the disk and ring to be heated in an oven. The ring and softened disk are then inverted and stretched downwardly over a positive model of a residual limb while a vacuum is introduced through holes within the model to form a plastic socket which conforms to the model. The interfitting connection may be peripherally spaced studs on the ring and projecting into corresponding holes in the disk or may be an annular rib or arcuate rib sections on the ring which project into an annular recess or arcuate cavities within the disk. After the plastic cools, the ring is separated for reuse.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: July 10, 2012
    Assignee: Bulldog Tools, Inc.
    Inventors: Robert B. Meyer, Wilbur N. Meyer
  • Patent number: 8173196
    Abstract: The invention concerns methods of coating stents and stents produced in accordance therewith. The object of the invention is to provide methods of coating stents with a polysaccharide layer which has improved adhesion capacity on the substrate surface of the implant, and to afford correspondingly functionalized stents. That is achieved inter alia by covalent bonding of a non-crosslinked hyaluronic acid to a substrate surface of the stent with the formation of hyaluronic acid layer and crosslinking of the hyaluronic acid layer.
    Type: Grant
    Filed: September 13, 2006
    Date of Patent: May 8, 2012
    Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co.
    Inventors: Gerd Bayer, Markus Nagel, Alexander Borck
  • Patent number: 8158041
    Abstract: Extruded, stretched, sintered tubular PTFE materials are produced which are suited for use in the medical field as liners and covers for expandable stents. The PTFE materials have an unusually low REC (Radial Expansion Coefficient) and RER (Radial Expansion Ratio).
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: April 17, 2012
    Assignee: Bard Peripheral Vascular, Inc.
    Inventor: William M. Colone
  • Patent number: 8122596
    Abstract: An image is captured or otherwise converted into a signal in an artificial vision system. The signal is transmitted to the retina utilizing an implant. The implant consists of a polymer substrate made of a compliant material such as poly(dimethylsiloxane) or PDMS. The polymer substrate is conformable to the shape of the retina. Electrodes and conductive leads are embedded in the polymer substrate. The conductive leads and the electrodes transmit the signal representing the image to the cells in the retina. The signal representing the image stimulates cells in the retina.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: February 28, 2012
    Assignees: Lawrence Livermore National Security, LLC, Doheny Eye Institute
    Inventors: Peter Krulevitch, Dennis L. Polla, Mariam N. Maghribi, Julie Hamilton, Mark S. Humayun, James D. Weiland
  • Patent number: 8116900
    Abstract: A method for fabricating a prosthetic limb socket component includes the following steps: (a) obtaining measurements of an individual's residual limb; (b) generating electronic data representing outer dimensions of the individual's residual limb utilizing (at least in part) the obtained measurements; (c) storing the electronic data representing outer dimensions of the individual's residual limb in an electronic record, where the electronic record includes cross-reference information; (d) manufacturing a first prosthetic limb socket component utilizing, at least in part, the electronic data representing outer dimensions of the individual's residual limb; (e) placing a permanent unique indicia on the prosthetic limb socket component, where the unique indicia includes data corresponding to the cross-reference information; and (f) utilizing the unique indicia data to access, with the assistance of a computer, the electronic record via the cross-reference information.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: February 14, 2012
    Assignee: Prosthetic Design, Inc.
    Inventors: Tracy C. Slemker, Robert Hoskins, Lucinda Busch, Scott R. Schall, Ralph Simmons
  • Patent number: 8084077
    Abstract: A one step method for drug coating an interventional device is disclosed by mixing a drug with a phosphorylcholine-linked methacrylate polymer in a liquid and applying the mixture to an interventional device, such as a stent, in a single step.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: December 27, 2011
    Assignee: Abbott Laboratories
    Inventors: Peter J. Tarcha, David Pecosky
  • Patent number: 8057396
    Abstract: Devices for assessing the size, shape, and topography of vessel lumens and hollow portions of organs are described. The devices are particularly adapted for determining the size, shape, topography, and compliance of the native heart valves to facilitate the later implantation of a prosthetic heart valve. The devices are typically catheter-based having an assessment mechanism fixed to a distal end of the catheter. The assessment mechanism generally includes an expandable member, such as a balloon. The assessment mechanism may also include an imaging member, a physical assessment member, an electronic mapping construction, an alignment mechanism, a valvuloplasty balloon, or any combination thereof.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: November 15, 2011
    Assignee: Phoenix Biomedical, Inc.
    Inventors: David C. Forster, Brian Beckey, Brandon Walsh, Scott Heneveld
  • Patent number: 8043854
    Abstract: In the transplant of a living organism tissue, such as a heart valve, taken from an animal, etc. into a human body, a cell removing solution for removing original cells from the living organism tissue is provided with flow approximately equal to the bloodstream of transplant recipient living body, and the living organism tissue is placed in the flow so as to effect immersion of the living organism tissue in the cell removing solution. In the immersion, it is preferred that the living organism tissue placed in the cell removing solution, while being rotated, be irradiated with microwave. As a result, original cells can be removed from the living organism tissue uniformly and reliably, so that the biocompatibility of living organism tissue after transplant can be enhanced.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: October 25, 2011
    Assignees: Waseda University, Selfusion Inc.
    Inventors: Mitsuo Umezu, Kiyotaka Iwasaki, Shigeyuki Ozaki, Yuji Morimoto, Osamu Endo
  • Patent number: 8007542
    Abstract: The invention involves a submucosa tissue that has the capability of being shape formed or shape configured. The submucosa involves a purified form of submucosa tissue. Optionally, the submucosa can be packaged in such a manner to permit sterility or maintain sterility of the submucosa.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: August 30, 2011
    Assignee: Cook Biotech Incorporated
    Inventors: Michael C. Hiles, Umesh H. Patel
  • Patent number: 7998201
    Abstract: Disclosed are implantable tissue augmentation devices, methods, and associated tools. The devices include an inflatable body, having an inner layer and an outer layer. A valve is provided for permitting the introduction of and retaining inflation media. At least one pull tab is provided on an end of the implant, to assist in positioning the implant. Kits and systems are also disclosed.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: August 16, 2011
    Assignee: Evera Medical, Inc.
    Inventor: Michael Lesh
  • Patent number: 7985442
    Abstract: An apparatus and method for imprinting a pattern on a medical device to provide a surface with greater surface area and improved adhesion properties.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: July 26, 2011
    Assignee: Abbott Laboratories Corporation
    Inventor: Victoria M. Gong
  • Patent number: 7967868
    Abstract: An orthopedic implant. The implant has a first portion including at least one patient-adjustable feature, and a second portion including at least one standard feature.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: June 28, 2011
    Assignee: Biomet Manufacturing Corp.
    Inventors: John R. White, Robert Metzger, Keith R. Berend
  • Patent number: 7959554
    Abstract: Described are methods and systems for drying remodelable materials, such that selective regions of the remodelable materials have differing properties. Also described are medical graft products having selective regions of differing material properties. Advantageous remodelable materials include collagenous extracellular matrix material, such as small intestine submucosa.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: June 14, 2011
    Assignee: Cook Biotech Incorporated
    Inventors: Chad S. McAlexander, Clay Fette, Jason P. Hodde, Matthew R. Graham
  • Patent number: 7959682
    Abstract: In order to provide a bone substitution material which enables mechanical stability and long-term in-vivo biocompatibility which can also be used for guided bone healing, the invention provides a method comprising the steps of providing a starting material comprising a mixture of at least a skeleton substance (20) and at least one functional substance, and building up a skeleton from the skeleton substance, thereby producing a profiled body (30), as well as a profiled body (30) containing a skeleton substance (20) and comprising a porous structure (10) with pores (12, 15) being interconnected with each other.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: June 14, 2011
    Assignee: ADC Advanced Dental Care GmbH & Co. KG
    Inventors: Matthias Epple, Drazen Tadic
  • Patent number: 7957831
    Abstract: A method is provided for determining the shape of a surgical linking device that is to be attached to a bony body structure such as the spinal column based on digitized locations of a plurality of attachment means engaged to the bony structure. The method is implemented by a computer system through a GUI to generate an initial bend curve to mate with the plurality of attachment means. The initial bend curve may be simplified based on user input to the GUI to reduce the number of bends necessary to produce a well-fitting linking device and may be altered to help obtain the goals of the surgery.
    Type: Grant
    Filed: October 7, 2008
    Date of Patent: June 7, 2011
    Inventor: Robert E. Isaacs
  • Patent number: 7941241
    Abstract: An optical fabrication method which is capable of adjusting a hardness and a density needed for each optical fabrication area in fabricating a three-dimensional fabricated article through sintering with a light beam, and is excellent in a working efficiency performs the steps of forming a powder layer of a predetermined thickness and then sintering the powder layer with a light beam, a predetermined number of times, cutting a periphery of the powder layers, and changing a degree of sintering by changing an amount of irradiation per unit area of a light-beam sintered surface according to a shortest distance from a peripheral surface of each powder layer.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: May 10, 2011
    Assignee: Matsuura Machinery Corporation
    Inventors: Norio Takinami, Toshio Maeda
  • Patent number: 7931687
    Abstract: Compositions, methods of production and use, and kits for an osteochondral graft involving both articular cartilage and underlying bone are provided.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: April 26, 2011
    Assignees: Articular Engineering, LLC, Rush University Medical Center
    Inventors: Koichi Masuda, Michael J. Hejna, Brian E. Pfister
  • Patent number: 7901447
    Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film. The cover may include one or more filaments, e.g., wires, which cooperate with the film to provide desirable mechanical properties. The wires may be integrated with the film by depositing the film over the wires.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: March 8, 2011
    Assignee: Boston Scientific SciMed, Inc.
    Inventors: Masoud Molaei, Beren W. Correa
  • Patent number: 7867426
    Abstract: A mold assembly and method of forming a surgical implant from bone cement. The method has the steps of connecting a plurality of mold segments to approximate the size of a patient implant. Each mold segment has an open channel. The method may further include aligning the channels of connected mold segments, positioning a centralizing holder on a reinforcement member, mixing bone cement, pouring at least some bone cement through the channels and into connected mold segments, fitting the reinforcement member into the mold segments, curing the bone cement; and removing the cured surgical implant.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: January 11, 2011
    Inventors: Bruce H. Ziran, Joseph W. Whiteside
  • Patent number: 7815687
    Abstract: The present invention relates to methods of treating tissue of the human body, specially, methods of promoting cell proliferation and ingrowth around implantable medical devices. The methods include inserting an apparatus comprising asperities adapted to injure native tissue at a desired anchoring location, injuring the native tissue at the desired anchoring location with the apparatus to initiate an injury response in the native tissue to thereby promote cell proliferation and ingrowth; and implanting the medical device at the treatment location.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: October 19, 2010
    Assignee: Med Institute, Inc.
    Inventors: Clinton D. Bahler, Alan R. Leewood, Jichao Sun
  • Patent number: 7811315
    Abstract: An implant valve for implantation in a blood vessel is comprised of a flexible tube and a hollow, substantially cylindrical support with a casing, expandable in diameter from an initial position to an implantation position. The support extends substantially coaxially over a part of the length of the tube along the inner wall of the tube. The casing of the support cooperates with the inner wall of the tube such that, in the implantation position, a first part of the tube can be formed into a rigid shell, which can be clamped substantially coaxially along the inner wall of a blood vessel. A second, axially contiguous part of the tube can then form a flexible, tubular valve body, which can extend substantially clear in the blood vessel. In an advantageous embodiment, the flexible tube comprises a vein turned inside out and the ends of the tube are connected to form a ring embracing the support.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: October 12, 2010
    Inventor: Cornelis Hendrikus Anna Wittens
  • Patent number: 7810233
    Abstract: An image is captured or otherwise converted into a signal in an artificial vision system. The signal is transmitted to the retina utilizing an implant. The implant consists of a polymer substrate made of a compliant material such as poly(dimethylsiloxane) or PDMS. The polymer substrate is conformable to the shape of the retina. Electrodes and conductive leads are embedded in the polymer substrate. The conductive leads and the electrodes transmit the signal representing the image to the cells in the retina. The signal representing the image stimulates cells in the retina.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: October 12, 2010
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Peter Krulevitch, Dennis L. Polla, Mariam N. Maghribi, Julie Hamilton, Mark S. Humayun, James D. Weiland