By Particle Count Patents (Class 702/26)
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Patent number: 11733184Abstract: A system for predicting rare earth elements (REEs) in a feedstock sample includes a measurement instrument that records a measurement for a sample, a processor communicatively coupled to the measuring instrument, and a memory communicatively coupled to the processor and containing machine readable instructions that, when executed by the processor, cause the processor to correlate the measurement series using a model; and predict a presence of one or more rare earth element based at least in part on the correlation. A method for predicting rare earth elements includes measuring feedstock samples via XRF or PGNAA, to generate a measurements of elements of interest with a lower atomic weight than REEs; correlating the measurements with a model; and predicting a presence of one or more rare earth elements based at least in part on the correlation.Type: GrantFiled: February 11, 2022Date of Patent: August 22, 2023Assignee: MICROBEAM TECHNOLOGIES, INC.Inventors: Matthew Fuka, Eric Kolb, Alexander Benson, Steven Benson
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Patent number: 11497420Abstract: Systems, methods, and computer readable storage media manage low blood glucose levels. The system receives blood glucose readings, where each reading includes a blood glucose value and a respective timestamp. The system compares each blood glucose reading to a predefined hypoglycemic event threshold, and identifies hypoglycemic events when a respective blood glucose reading is below the predefined hypoglycemic event threshold. For at least a subset of the identified hypoglycemic events, the system prompts a user for information associated with each hypoglycemic event. The information requested includes one or more of: symptoms associated with the respective hypoglycemic event; perceived causes of the respective hypoglycemic event; and treatment for the respective hypoglycemic event. In response to the prompting, the system obtains feedback about the identified hypoglycemic events and provides a report that includes at least a subset of the obtained feedback.Type: GrantFiled: June 18, 2019Date of Patent: November 15, 2022Assignee: GLOOKO INC.Inventors: Samuel Wynbrandt, Rita Sharma, Daniel Todorov
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Patent number: 11232935Abstract: The compound list stored in identification information memory is populated with theoretical masses associated with a variety of compounds, as well as information such as the type of matrix capable of detecting said compound, potential neutral loss, etc. The adduct ion list, meanwhile, is populated with theoretical masses associated with a variety of adduct ions, as well as other information such as types of matrices capable of producing adducts, etc. When a user specifies a peak on the mass spectrum for a compound search, compound candidate search portion extracts combination candidates based on how well the measured m/z value of the specified peak matches the m/z value for combinations of compounds in the compound list and adduct ions in the adduct ion list, while the type of matrix used during measurement serves as a condition to narrow down the combinations. Display processing portion displays a list of the search results.Type: GrantFiled: September 1, 2016Date of Patent: January 25, 2022Assignee: SHIMADZU CORPORATIONInventors: Masahiro Ikegami, Koretsugu Ogata
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Patent number: 10920606Abstract: Methods and systems for diagnosing a condition of an engine based on lubrication fluid analysis are disclosed. One embodiment of the methods comprises: receiving input data representative of a respective geometric parameter and a respective chemical composition for a plurality of particles filtered from a sample of fluid obtained from the engine; generating data representative of a mass of material of a chemical composition category in one or more of the particles; comparing the mass of material of the chemical composition category with reference data; and generating output data representative of a diagnosis of the condition of the engine.Type: GrantFiled: November 21, 2019Date of Patent: February 16, 2021Assignee: PRATT & WHITNEY CANADA CORP.Inventors: Maurice Jean, Daniel Meilleur
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Patent number: 10519800Abstract: Methods and systems for diagnosing a condition of an engine based on lubrication fluid analysis are disclosed. One embodiment of the methods comprises: receiving input data representative of a respective geometric parameter and a respective chemical composition for a plurality of particles filtered from a sample of fluid obtained from the engine; generating data representative of a mass of material of a chemical composition category in one or more of the particles; comparing the mass of material of the chemical composition category with reference data; and generating output data representative of a diagnosis of the condition of the engine.Type: GrantFiled: December 8, 2015Date of Patent: December 31, 2019Assignee: PRATT & WHITNEY CANADA CORP.Inventors: Maurice Jean, Daniel Meilleur
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Patent number: 10371631Abstract: There is provided an optical analysis technique of detecting light of a light-emitting particle in a sample solution in the scanning molecule counting method using the light measurement with a confocal or multiphoton microscope, for suppressing the scattering in detected results of signals of light of light-emitting particles smaller and achieving the improvement of accuracy. The inventive technique comprises moving the position of a light detection region along a predetermined route for multiple circulation times by changing the optical path of the optical system; detecting light from the light detection region and generating time series light intensity data during the moving of the light detection region and detecting individually a signal indicating light from each light-emitting particle existing in the predetermined route using the time series light intensity data obtained in the circulating movements of the light detection region of multiple times.Type: GrantFiled: February 24, 2014Date of Patent: August 6, 2019Assignee: OLYMPUS CORPORATIONInventors: Tetsuya Tanabe, Mitsushiro Yamaguchi
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Patent number: 9984039Abstract: Efficient prediction of trajectories of pollutants in a fluid is accomplished by automatic activation and deactivation of sub-domains within the mesh representing the body of fluid in question. Activation and deactivation are triggered by the transport characteristics of the pollutant, that is, the sub-domains are activated as the pollutant enters a sub-domain and deactivated as the pollutant exits a sub-domain.Type: GrantFiled: September 25, 2014Date of Patent: May 29, 2018Assignee: International Business Machines CorporationInventors: Emanuele Ragnoli, Sergiy Zhuk
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Patent number: 9863806Abstract: In the scanning molecule counting method using the light measurement with a confocal microscope or a multiphoton microscope, a measuring time is optimized with suppressing the scattering in a result small irrespective of light-emitting particle concentrations. In the inventive technique of detecting and analyzing the light from an light-emitting particle, there are repeated processes of detecting the light intensity from a light detection region with moving the position of the light detection region of an optical system in a sample solution by changing the optical path of the optical system of the microscope, and detecting the signals of the light of light-emitting particles individually, and based on the time taken for the number of the signals from the light-emitting particles to reach a predetermined number, the light-emitting particle concentration in the sample solution is determined.Type: GrantFiled: July 19, 2013Date of Patent: January 9, 2018Assignee: OLYMPUS CORPORATIONInventor: Tetsuya Tanabe
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Patent number: 9644230Abstract: A method for detecting bacteria and determining the concentration thereof in a liquid sample includes the steps of taking an optical section through a container holding a volume of the liquid sample at a predetermined field of view and at a predetermined focal plane depth or angle and after a period of time has elapsed to allow non-bacteria in the sample to settle to the bottom of the container. Since bacteria auto arranges in the liquid sample, forming a lattice-like grid pattern, an optical section through the volume of auto-arranged bacteria may be used to measure the quantity of bacteria residing in that section. A container for holding the liquid sample has particular structure which aids in separating the non-bacteria from the bacteria.Type: GrantFiled: October 28, 2014Date of Patent: May 9, 2017Assignee: IDEXX Laboratories, Inc.Inventors: Jeremy Hammond, James Russell
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Patent number: 9528923Abstract: There is provided optical analysis techniques in the scanning molecule counting method using the light measurement with a confocal or multiphoton microscope in which the measuring unit time in the light measurement is set to an appropriate value in order to surely detect an approximately bell shape profile of the signal of a light-emitting particle and avoid excessive increase data volume of time series light intensity data. The inventive optical analysis technique of detecting light of a light-emitting particle in a sample solution generates time series light intensity data of light from a light detection region detected during moving the position of the light detection region of a microscope in the sample solution and detects in the data a signal indicating light from each light-emitting particle individually. The measuring unit time is determined based on the size and the moving speed of the light detection region.Type: GrantFiled: February 26, 2014Date of Patent: December 27, 2016Assignee: OLYMPUS CORPORATIONInventors: Hidetaka Nakata, Tetsuya Tanabe
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Patent number: 9488578Abstract: There is provided a single particle detection technique based on a scanning molecule counting method, enabling individual detection of a single particle using light measurement with a confocal or multiphoton microscope, and quantitative observation of conditions or characteristics of the particle. The inventive technique of detecting a single particle in a sample solution detects light containing substantially constant background light from a light detection region with moving the position of the light detection region of the microscope in a sample solution to generate time series light intensity data; and detects individually a light intensity reduction occurred when a single particle which does not emit light (or a particle whose emitting light intensity in a detected wavelength band is lower than the background light) enters in the light detection region in the time series light intensity data as a signal indicating the existence of each single particle.Type: GrantFiled: January 23, 2014Date of Patent: November 8, 2016Assignee: OLYMPUS CORPORATIONInventors: Takuya Hanashi, Tetsuya Tanabe
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Patent number: 9354171Abstract: There is provided a single particle detection technique based on a scanning molecule counting method, enabling individual detection of a single particle using light measurement with a confocal or multiphoton microscope, and quantitative observation of conditions or characteristics of the particle. The inventive technique of detecting a single particle in a sample solution detects light containing substantially constant background light from a light detection region with moving the position of the light detection region of the microscope in a sample solution to generate time series light intensity data; and detects individually a light intensity reduction occurred when a single particle which does not emit light (or a particle whose emitting light intensity in a detected wavelength band is lower than the background light) enters in the light detection region in the time series light intensity data as a signal indicating the existence of each single particle.Type: GrantFiled: January 23, 2014Date of Patent: May 31, 2016Assignee: OLYMPUS CORPORATIONInventors: Takuya Hanashi, Tetsuya Tanabe
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Patent number: 9023651Abstract: The invention relates to a method and a device (100) for determining the amount of a target component (2) in a sample, wherein magnetic particles (2) can bind to a contact surface (4) with kinetics that depend on the sample-amount of the target component. The method comprises at least two washing steps during which magnetic particles (2) are magnetically moved away from the contact surface (4) and corresponding measurements of the remaining amount of magnetic particles (2) at the contact surface (4). The amount of target component in the sample is estimated from at least one of such measurement results. The measurement allows to determine also high concentrations of target component for which the sensor surface (4) is saturated in a steady-state.Type: GrantFiled: October 6, 2009Date of Patent: May 5, 2015Assignee: Koninklijke Philips N.V.Inventors: Toon Hendrik Evers, Wendy Uyen Dittmer
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Publication number: 20150118708Abstract: A method for detecting bacteria and determining the concentration thereof in a liquid sample includes the steps of taking an optical section through a container holding a volume of the liquid sample at a predetermined field of view and at a predetermined focal plane depth or angle and after a period of time has elapsed to allow non-bacteria in the sample to settle to the bottom of the container. Since bacteria auto arranges in the liquid sample, forming a lattice-like grid pattern, an optical section through the volume of auto-arranged bacteria may be used to measure the quantity of bacteria residing in that section. A container for holding the liquid sample has particular structure which aids in separating the non-bacteria from the bacteria.Type: ApplicationFiled: October 28, 2014Publication date: April 30, 2015Inventors: Jeremy Hammond, James Russell
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Patent number: 8941056Abstract: A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitized. Arrival time and intensity pairs are calculated for both digitized signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum.Type: GrantFiled: May 6, 2014Date of Patent: January 27, 2015Assignee: Micromass UK LimitedInventors: Martin Raymond Green, Steven Derek Pringle, Jason Lee Wildgoose
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Patent number: 8889072Abstract: Disclosed are computer-implemented methods of sorting particles from a particle stream in a flow cytometer. The methods include: calculating sort decision making parameters using the raw event data values from a flow cytometer and a sort logic; performing sort logic computations using the sort logic definition and the sort decision making parameters to generate sort decisions; converting the sort decisions into sort commands; and sending the one or more sort commands to the flow cytometer. Sort logic computations may include algorithmically using conditional branching logic, and may include sort logic equations having mathematical functions characterizing one or more regions of interest in multidimensional data space. Such mathematical functions may be determined based on one or more parameters provided by a user. Also disclosed are corresponding systems having a flow cytometer and a computer.Type: GrantFiled: September 13, 2012Date of Patent: November 18, 2014Assignee: Beckman Coulter, Inc.Inventors: Jeffrey W. Degeal, Charles S. Bay, Edward A. Stanton, Paul Barclay Purcell, George C. Malachowski
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Patent number: 8805586Abstract: The present invention relates to a system for optimizing and controlling the particle size distribution and scale-up of production of nanoparticle in an aerosol flame reactor. The method provides nanoparticles with desired, optimized and controlled particle size and the specific surface area in aerosol reactors using a simulation tool with programmed instructions. The simulation tool couples flame dynamics model and particle population balance model.Type: GrantFiled: July 11, 2011Date of Patent: August 12, 2014Assignee: Tata Consultancy Services LimitedInventors: Venkataramana Runkana, Venkata Sudheendra Buddhiraju, Nagaravi Kumar Varma Nadimpalli
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Patent number: 8781755Abstract: A method of obtaining a fugitive emission flux measurement of airborne matter is provided. The method involves measuring the airborne matter along one or more than one measurement surface that spans the fugitive emission using two or more than two measurement beam paths where each of the two or more than two measurement beam paths are parallel to each other, or substantially parallel to each other, and determining a mass per unit length measurement for the measurement surface, determining a representative wind velocity at or near the one or more than one measurement surface, and calculating the fugitive emission flux of the airborne matter in mass per unit time using the mass per unit length determination and representative wind velocity.Type: GrantFiled: December 9, 2010Date of Patent: July 15, 2014Assignee: Golder Associates Ltd.Inventor: Colin Irvin Wong
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Patent number: 8754364Abstract: A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised. Arrival time and intensity pairs are calculated for both digitised signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum.Type: GrantFiled: January 10, 2013Date of Patent: June 17, 2014Assignee: Micromass UK LimitedInventors: Martin Raymond Green, Steven Derek Pringle, Jason Lee Wildgoose
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Patent number: 8674554Abstract: A power off delay circuit includes a switch connected between an external power input terminal and an internal power supply terminal, a capacitor connected to the internal power supply terminal, and a hysteresis comparator to switch the switch according to the voltages of the external power input terminal and the internal power supply terminal. During on-time of the switch, the external power input terminal is connected to the internal power supply terminal and the capacitor can be charged by the external power source. When the switch is off, the capacitor provides electric power for an internal circuit. Application of the power off delay circuit to an audio system may eliminate the turn-off pops of the audio system.Type: GrantFiled: June 18, 2010Date of Patent: March 18, 2014Assignee: Richtek Technology Corp.Inventors: Chi-Hua Lin, Chien-Fu Tang, Isaac Y Chen, An-Tung Chen
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Patent number: 8571812Abstract: A method for determining the oxygen concentration of a sample made of a semiconductor material includes a heat treatment step of the sample to form thermal donors, the measurement of the resistivity in an area of the sample, the determination of the thermal donor concentration from a relation expressing the charge carrier mobility according to an ionized dopant impurity concentration, by adding to the dopant impurity concentration four times the thermal donor concentration, and from the measured resistivity value. The method finally includes determining the oxygen concentration from the thermal donor concentration.Type: GrantFiled: August 30, 2011Date of Patent: October 29, 2013Assignee: Commissariat a l'Energie Atomique et aux Energies AlternativesInventors: Jordi Veirman, Sebastien Dubois, Nicolas Enjalbert
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Publication number: 20130275054Abstract: A method and apparatus for photon, ion or particle counting described that provides seven orders of magnitude of linear dynamic range (LDR) for a single detector. By explicitly considering the log-normal probability distribution in voltage transients as a function of the number of photons, ions or particles present, the binomial distribution of observed counts for a given threshold, the mean number of photons, ions or particles can be determined well beyond the conventional limit.Type: ApplicationFiled: September 27, 2011Publication date: October 17, 2013Applicant: Purdue Research FoundationInventors: Garth J. Simpson, David Joseph Klsslck, Ryan Muir
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Patent number: 8557587Abstract: Disclosed is a self-tuning flow cytometer that uses a mathematical model to perform sort decisions that is based upon the biological response of the particular types of cells that are being sorted. In one embodiment, statistical calculations of the likelihood of an event belonging to a certain population are used to make the sort decisions. Automated self-tuning processes are used to optimize the operating parameters of the flow cytometer to achieve a selected purity with higher yield at optimal sorting speeds. The fully automated processes minimize user input and allows the user to select a desired purity while maximizing yield.Type: GrantFiled: January 6, 2010Date of Patent: October 15, 2013Assignee: XY, LLCInventors: Daniel N. Fox, George C. Malachowski, Matthias J. G. Ottenberg, Tidhar Sadeh
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Patent number: 8505276Abstract: Disclosed is a particulate matter measurement device that continuously measures changes in a mass of particulate matters contained in an exhaust gas under dynamic operating conditions. The device dilutes and separates the flow of exhaust gas while an engine is operating. The particulate matters contained in one of the exhaust gas streams are collected by a collection filter to measure the mass and the remainder is measured by a mass-related value measurement. Then, time series change data for the mass of the particulate matter are found based on correlations of the individual measured data. With this arrangement, the flow volume of the dilute exhaust gas that passes through the collection filter and the flow volume of the dilute exhaust gas that is introduced into the mass-related value measurement device are ensured by adjusting the flow volume of the diluting gas that dilutes the exhaust gas.Type: GrantFiled: July 13, 2009Date of Patent: August 13, 2013Assignee: Horiba, Ltd.Inventor: Hiroshi Nakamura
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Patent number: 8395398Abstract: Mixtures containing homogeneously-sized particles with a minimum concentration of agglomerates or larger particles are desired in various manufacturing processes such as, for example, in the manufacture and use of chemical mechanical polishing slurries, food emulsions, pharmaceutical products, paints, and print toner. The method disclosed herein provides these industries with an accurate and efficient method of screening such mixtures for such agglomerates and large particles. The method generally includes preparing a suspension of the mixture in an electrolyte, wherein the suspension includes a specified concentration of small particles per unit of electrolyte. The method further includes passing the prepared suspension, and a plurality of the particles therein, through an aperture of a device capable of characterizing particles according to the Coulter principle to obtain data on the particles.Type: GrantFiled: April 23, 2010Date of Patent: March 12, 2013Assignee: Beckman Coulter, Inc.Inventors: Renliang Xu, Yiming Yang
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Publication number: 20130035871Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.Type: ApplicationFiled: August 3, 2012Publication date: February 7, 2013Applicant: DexCom, Inc.Inventors: Phil Mayou, Hari Hampapuram, David Price, Keri Weindel, Kostyantyn Snisarenko, Michael Robert Mensinger, Leif N. Bowman, Robert J. Boock, Apurv Ullas Kamath, Eli Reihman, Peter C. Simpson
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Patent number: 8364422Abstract: A method of presuming interior situation of process chamber that makes it possible to accurately presume the interior situation of a process chamber using the number of particles discharged from the interior of the process chamber. Characteristic values associated with respective particle removing modes of a particle removing sequence are extracted from time-series data on the number of particles discharged from the interior of the process chamber in which a substrate is accommodated and subjected to predetermined processing and to which the particle removing sequence is applied, and the relationship between the extracted characteristic values and the interior situation of the process chamber is calculated. The interior situation of the process chamber is presumed based on the calculated relationship and the characteristic values in new time-series data on the number of particles.Type: GrantFiled: May 27, 2009Date of Patent: January 29, 2013Assignee: Tokyo Electron LimitedInventor: Hiroyuki Nakayama
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Patent number: 8354634Abstract: A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised. Arrival time and intensity pairs are calculated for both digitised signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum.Type: GrantFiled: May 22, 2008Date of Patent: January 15, 2013Assignee: Micromass UK LimitedInventors: Martin Green, Steven Derek Pringle, Jason Lee Wildgoose
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Publication number: 20120303291Abstract: A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.Type: ApplicationFiled: April 25, 2012Publication date: November 29, 2012Applicant: Lawrence Livermore National Security, LLCInventors: Manoj K. Prasad, Neal J. Snyderman, Mark S. Rowland
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Patent number: 8265110Abstract: A laser and monitoring system is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention employs a femtosecond laser and binary pulse shaping (BPS). Still another aspect of the present invention uses a laser beam pulse, a pulse shaper and a SHG crystal. In yet another aspect of the present invention, a multiphoton intrapulse interference phase scan (hereinafter “MIIPS”) method is used to characterize the spectral phase of femtosecond laser pulses and to correct them. A further aspect of the system of the present invention is employed to monitor environmental chemicals and biological agents, including toxins, explosives, and diseases.Type: GrantFiled: June 22, 2009Date of Patent: September 11, 2012Assignee: Board of Trustees Operating Michigan State UniversityInventors: Marcos Dantus, Vadim V. Lozovoy, Matthew Comstock
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Patent number: 8265882Abstract: A method and a device for the automatic determination of selected physical and colloidal chemistry parameters by determining the attenuation of radiated waves through monodisperse or polydisperse dispersion samples subjected to gravitation or centrifugation, wherein during the segregation by means of centrifugation or gravitation, the instantaneous transmission IT(t, r) characterizing the current segregation status of the waves radiated with the intensity Io(t, r) and/or the instantaneous scattering IS(t, r) as a function of the position within the samples is repeatedly determined and recorded at high resolution at any arbitrary time for one or more wavelengths over the entire length of the sample or in selected partial sections of it, simultaneously for multiple and even concentrated samples with known and/or unknown physical and colloidal chemistry properties.Type: GrantFiled: March 4, 2005Date of Patent: September 11, 2012Assignee: L.U.M. Gesellschaft fur Labor-Umweltdiagnostic & Medizintechnik mbHInventors: Dietmar Lerche, Titus Sobisch, Torsten Detloff, Frank Babick, Michael Stintz
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Publication number: 20120046883Abstract: A pipette instrument 100 carrying interrogation circuitry 132 adapted to interrogate a data signal received from a removable instrumented pipette tip 114. The pipette 100 includes a microprocessor and memory 130 that can be programmed to perform data collection procedures. User controls typically include a start button 108, and a track wheel 1 10. A display device 1 12 can present device options through one or more menu, and show data resulting from one or more test result. The pipette can interrogate particles carried by a fluid flowing through a tip 1 14 by detecting either of or both of Coulter principle phenomena, and Stokes-shift phenomena.Type: ApplicationFiled: April 27, 2009Publication date: February 23, 2012Inventors: Harold E. Ayliffe, Michael E. McGinnis, Curts S. King
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Patent number: 8082112Abstract: The concentration of air or other agents in a fluid delivery line is determined by monitoring agent signals and processing those agent signals along with information regarding the age of each agent signal. The processor determines a primary agent concentration value based on the received agent signal values, with the primary agent concentration value determined by giving greater weight to more recent agent signal values. Where the primary agent concentration value exceeds a primary threshold value, an alarm signal may be activated. The processor also may determine a secondary agent concentration value, which may be determined from the actual agent signal values instead of the weighted agent signal values. Where the secondary agent concentration value exceeds a secondary threshold value, an alarm signal may be activated.Type: GrantFiled: November 27, 2006Date of Patent: December 20, 2011Assignee: CareFusion 303, Inc.Inventors: Robert D. Butterfield, Allen B. Farquhar
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Patent number: 8059264Abstract: Method for monitoring the velocity of growing polymer particles flowing in a two-phase stream during a polymerization process, said method comprising measuring the degree of attenuation in the propagation of light in said two-phase stream by means of a photometric instrument, said photometric instrument comprising: one or more transmitting optical waveguides connecting one or more light sources to said two-phase stream, one or more receiving optical waveguides connecting said two-phase stream to a light detector.Type: GrantFiled: February 24, 2004Date of Patent: November 15, 2011Assignee: Basell Poliolefine Italia, s.r.l.Inventors: Christian Ulrich Schmidt, Stefan Ziegler, Gabriele Mei, Stefano Bertolini, Gerben Meier
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Patent number: 8055471Abstract: A method for discriminating particle groups comprises generating, by a particle analyzer, a particle characteristic distribution histogram in which the abscissa indicates respective channels for representing the characteristics of the particles, and the ordinate indicates the particle count; setting a valid area selection height in the particle characteristics distribution histogram; and generating an equivalent negative histogram based on the set height and the particle characteristic distribution histogram.Type: GrantFiled: February 17, 2009Date of Patent: November 8, 2011Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Huan Qi, Wenjun Tong
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Patent number: 8032321Abstract: A biosensor system determines the presence and/or concentration of an analyte in a sample using one or more calibrated correlation equations. The analysis may be electrochemical, optical, or a combination thereof. The biosensor system may be implemented using a measurement device and a sensor strip. The measurement device applies test signals to a multi-layered encoding area of the sensor strip. Calibration information is determined from the patterns generated by the interaction of the test signals with the multi-layered encoding area.Type: GrantFiled: July 15, 2008Date of Patent: October 4, 2011Assignee: Bayer Healthcare LLCInventor: Weiping Zhong
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Patent number: 7982181Abstract: A method of analyzing data from a mass spectrometer provides data-dependent acquisition. An extracted ion chromatogram (XIC) is created for each m/z data point of mass spectral scans and the XIC for each m/z data point are correlated to a model function to obtain a XIC correlation value. A weighting function is applied to the XIC correlation value to obtain a current weighted intensity for each m/z point, which is used to reconstruct a weighted mass spectrum. The value or range of intensities of interest of the weighted intensity data or raw data is transformed from the time domain into the frequency domain, and the transformed data is used to make a real-time decision for the data-dependent acquisition. The data-dependent acquisition can be the performance of tandem mass spectrometry. A sample processing apparatus receives the sample and a computer readable medium provides instructions to the apparatus.Type: GrantFiled: January 15, 2008Date of Patent: July 19, 2011Assignee: Thermo Finnigan LLCInventor: Michael W. Senko
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Patent number: 7943383Abstract: A blood analyzer configured to prevent an abnormal number of white blood cells caused by lipid particles or red blood cells of poor hemolysis from being output. The blood analyzer includes a system for obtaining a first white blood cell number and a system for obtaining a second white blood cell number. The analyzer also includes an output device for outputting the second white blood cell number, and a system for determining whether the second white blood cell number is abnormal. The output device is configured to output the first white blood cell number when the second white blood cell number has been determined to be abnormal.Type: GrantFiled: June 28, 2007Date of Patent: May 17, 2011Assignee: Sysmex CorporationInventors: Kinya Uchihashi, Yoshiro Ikeuchi, Noriyuki Narisada
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Patent number: 7895000Abstract: An environmental sensor including an inlet and an outlet such that a flow of fluid moves from the inlet to the outlet, a particle detection portion to detect particles in the fluid, and a controller connected to the particle detection portion. The environmental sensor can be in communication with a data acquisition system (e.g., via a wireless access point) to form a particle counting system. Also disclosed are methods of operating the environmental sensor and methods of operating the particle detection system.Type: GrantFiled: September 4, 2007Date of Patent: February 22, 2011Assignee: Venturedyne, Ltd.Inventors: David L. Chandler, Daniel Edward Cain, Glenn Y. Kozuma, Joe Somoza
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Patent number: 7880483Abstract: An object of the present invention is to provide a quality inspection method for obtaining a specifying factor which can more reliably indicate powder characteristics of a core material for an electrophotographic ferrite carrier. The method includes measuring an impedance of the core material for the electrophotographic ferrite carrier to obtain a Cole-Cole plot in which a real number impedance is arranged in an X-axis and an imaginary number impedance is arranged in a Y-axis, and evaluating characteristics of particles of the core material for the electrophotographic ferrite carrier using the Cole-Cole plot.Type: GrantFiled: March 28, 2008Date of Patent: February 1, 2011Assignee: Powdertech Co., Ltd.Inventors: Koji Aga, Hiromichi Kobayashi
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Patent number: 7871237Abstract: A method and system for monitoring a gas turbine engine (20) to predict maintenance requirements. Particles suspended in a gas flow (24, 32) of the engine (20) are monitored and quantified to predict a particle accumulation rate. Monitoring may be done using particle flow sensors (61-63) in a diverted portion (33) of the working gas flow (24), such as in the cooling gas flow (32). Particle sampling (S1-S3) may be done to determine particle size and composition distributions. Particle mass flow rates may then be continuously monitored per engine operating condition, and compared to predetermined values such as a normal upper limit per engine operating condition. An integrated particle mass flow may be used in conjunction with an instantaneous mass flow rate to predict a maintenance requirement. Multiple locations (L1-L3) may be monitored to recognize a maintenance requirement by flow section or component.Type: GrantFiled: July 7, 2006Date of Patent: January 18, 2011Assignee: Siemens Energy, Inc.Inventors: Richard H. Bunce, Francisco Dovali-Solis
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Patent number: 7825373Abstract: A data acquisition system and method are described that may be used with various spectrometers. The data acquisition system may include an ion detector, an initial processing module, and a spectra processing module. The initial processing module is provided for receiving, sampling, and processing ion detection signals received from the ion detector, and for supplying processed signals to the spectra processing module. The initial processing module includes a horizontal accumulation circuit that combines a fractional number of adjacent samples of the ion detection signals into bins. The number of adjacent samples to combine into bins may vary as a function of: (1) the time of arrival at the ion detector corresponding to that sample; (2) the mass corresponding to that sample; (3) the resolution corresponding to that sample; and/or (4) an operational mode of the spectrometer. The spectra processing module receives the processed signals and generates spectra.Type: GrantFiled: September 4, 2008Date of Patent: November 2, 2010Assignee: Leco CorporationInventors: Peter M. Willis, Michael C. Mason, Mark R. Wheeler, Viatcheslav B. Artaev, Julie R. Pitz
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Patent number: 7791482Abstract: A material is laced with Radio Frequency Identification (RFID) tags at a known concentration of RFID tags per unit of material. Subsequently, if an interrogation of the RFID tags reveals a reduced concentration of RFID tags in the material, then a conclusion is drawn that the material has been diluted.Type: GrantFiled: March 20, 2008Date of Patent: September 7, 2010Assignee: International Business Machines CorporationInventors: Robert L. Angell, James R. Kraemer
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Patent number: 7724150Abstract: An environmental sensor including an inlet and an outlet such that a flow of fluid moves from the inlet to the outlet, a particle detection portion to detect particles in the fluid, and a controller connected to the particle detection portion. The environmental sensor can be in communication with a data acquisition system (e.g., via a wireless access point) to form a particle counting system. Also disclosed are methods of operating the environmental sensor and methods of operating the particle detection system.Type: GrantFiled: September 4, 2007Date of Patent: May 25, 2010Assignee: Venturedyne, Ltd.Inventors: David L. Chandler, Daniel Edward Cain, Glenn Y. Kozuma, Joe Somoza
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Publication number: 20100045982Abstract: A particle counting device 11 for detecting and counting particles in a fluid to be measured comprises a measuring section 13 for detecting particles and a control section 12 for processing the output signal from the measuring section 13. When an abnormality occurs, a signal to issue a warning is generated. With this, a constant monitoring or observation is possible. Also, a particle counting system comprising a plurality of particle counting devices 11 and an information processing device 17 for processing the results of the counting by the particle processing devices 11 is also provided. The plurality of particle counting devices 11 are electrically connected to the information processing device 17 in multiple and in parallel. Alternately, a particle counting system comprising a plurality of particle counting devices 11 for detecting and counting particles in a fluid to be measured is also provided.Type: ApplicationFiled: November 28, 2006Publication date: February 25, 2010Applicant: NIDEC SANKYO CORPORATIONInventors: Haruhiro Tsuneta, Eiichi Sugioka, Hiroshi Tonouchi, Junichi Shiozawa, Kenichi Hayashi, Tetsuo Momose, Hiroaki Furihata
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Patent number: 7657384Abstract: Method for managing a response to a triggering event in connection with a fugitive emissions monitor of a component. In one implementation, the method may include determining whether an input is a triggering event. If the input is a triggering event, then a message regarding the triggering event and one or more actions to remedy the triggering event may be displayed. The method may further include displaying one or more queries to confirm that the actions have been completed.Type: GrantFiled: March 28, 2007Date of Patent: February 2, 2010Assignee: Environmental Analytics, Inc.Inventor: Rex Moses
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Publication number: 20090315533Abstract: An apparatus for characterizing particles suspended in a liquid sample containing electrolyte including a sample chamber to hold the liquid sample and a collection chamber to hold an electrolyte solution. A wall separates the chambers and includes an aperture to allow passage of particles between the chambers; and a pair of electrodes are disposed on opposite sides of the aperture to induce a current through the aperture. A pressure source forces the sample to pass from the sample chamber into the collection chamber; and a processor measures a signal representative of electric resistance variation between the electrodes to enable determination of the size of the particle within the liquid passing through the aperture, wherein the processor is adapted to monitor two or more parameters characterizing the flow of particles through the aperture, and to detect a potential blockage of the aperture by detecting a change in any one of the parameters.Type: ApplicationFiled: June 18, 2009Publication date: December 24, 2009Applicant: BECKMAN COULTER, INC.Inventors: Peter Atchley, Scott D'Amron
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Publication number: 20090299652Abstract: A method of presuming interior situation of process chamber that makes it possible to accurately presume the interior situation of a process chamber using the number of particles discharged from the interior of the process chamber. Characteristic values associated with respective particle removing modes of a particle removing sequence are extracted from time-series data on the number of particles discharged from the interior of the process chamber in which a substrate is accommodated and subjected to predetermined processing and to which the particle removing sequence is applied, and the relationship between the extracted characteristic values and the interior situation of the process chamber is calculated. The interior situation of the process chamber is presumed based on the calculated relationship and the characteristic values in new time-series data on the number of particles.Type: ApplicationFiled: May 27, 2009Publication date: December 3, 2009Applicant: TOKYO ELECTRON LIMITEDInventor: Hiroyuki NAKAYAMA
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Patent number: 7583710Abstract: A laser and monitoring system is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention employs a femtosecond laser and binary pulse shaping (BPS). Still another aspect of the present invention uses a laser beam pulse, a pulse shaper and a SHG crystal. In yet another aspect of the present invention, a multiphoton intrapulse interference phase scan (hereinafter “MIIPS”) method is used to characterize the spectral phase of femtosecond laser pulses and to correct them. A further aspect of the system of the present invention is employed to monitor environmental chemicals and biological agents, including toxins, explosives, and diseases.Type: GrantFiled: July 2, 2004Date of Patent: September 1, 2009Assignee: Board of Trustees operating Michigan State UniversityInventors: Marcos Dantus, Vadim V Lozovoy, Matthew Comstock
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Publication number: 20090210170Abstract: A method for discriminating particle groups comprises generating, by a particle analyzer, a particle characteristic distribution histogram in which the abscissa indicates respective channels for representing the characteristics of the particles, and the ordinate indicates the particle count; setting a valid area selection height in the particle characteristics distribution histogram; and generating an equivalent negative histogram based on the set height and the particle characteristic distribution histogram.Type: ApplicationFiled: February 17, 2009Publication date: August 20, 2009Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Huan QI, Wenjun TONG