Quantitative Determination (e.g., Mass, Concentration, Density) Patents (Class 702/23)
  • Patent number: 10825672
    Abstract: Techniques and apparatus for analyzing mass spectrometry data are described. In one embodiment, for example, an apparatus may include logic to access a product ion data set generated via mass analyzing a sample comprising a target precursor, access precursor composition information for elements of the target precursor that includes nominal mass and mass defect information, determine nominal mass (NM)-mass defect (MD) relationship information for ion fragments associated with the target precursor based on the precursor composition information, determine one or more fragment upper boundaries and one or more fragment lower boundaries, extract candidate ion fragments from the ion fragments via applying the one or more fragment upper boundaries and the one or more fragment lower boundaries to the NM-MD relationship information, and determine target ion fragments from the plurality of candidate ion fragments based on fragmentation efficiency information associated with the candidate ion fragments.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: November 3, 2020
    Assignee: WATERS TECHNOLOGIES CORPORATION
    Inventors: Scott J. Geromanos, Curt Devlin, Steven J. Ciavarini
  • Patent number: 10802005
    Abstract: A chromatogram data processing system having an impurity detector including a differential chromatogram creator, a purity curve creator and a determiner. The differential chromatogram creator calculates a differential coefficient of an absorbance spectrum with respect to wavelength at a local maximum or local minimum absorption wavelength of the target component, and creates a differential chromatogram which shows a temporal change of the differential coefficient. The purity curve creator creates a purity curve which shows a temporal change of the difference between the degree of similarity of a spectrum on the target peak to a reference spectrum and a threshold of the degree of similarity which is determined taking into account the influence of noise components. The differential chromatogram and the purity curve are displayed on a display unit in a superposed form on a wavelength chromatogram created by a wavelength chromatogram creator.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: October 13, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Kenichi Mishima, Etsuho Kamata, Hiroshi Miura, Yasuhiro Mito, Toshinobu Yanagisawa
  • Patent number: 10794880
    Abstract: Sequential identification numbers are automatically provided and undisplayed, constant, unique numbers are assigned to each event registered in an analysis condition setting table 100. Since correspondence information between the identification numbers and the unique numbers changes due to the reassignment of identification numbers when an event is deleted from the table, event identification numbers for each compound are changed by referring to the correspondence information on a compound information table. As a result, it is possible to avoid the misalignment of event identification numbers between both tables. In addition, when an instruction is given to coordinate the time information or m/z information on both tables, the information on one table is reflected on the other table in accordance with the identification numbers.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: October 6, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Yutaro Yamamura, Tohru Shiohama, Yuji Katsuyama
  • Patent number: 10741372
    Abstract: As soon as a set of data is acquired by a mass spectrometric analysis, an accumulated value of the signal intensity on the mass spectrum is calculated for each m/z segment obtained by dividing the entire m/z range covered by the measurement by a predetermined m/z width. Only the m/z segments with accumulated signal-intensity values equal to or greater than a predetermined threshold are selected as the target for an MS/MS analysis. MS/MS analysis is performed for each selected m/z segment, using ions whose m/z values fall within the m/z segment as precursor ions. A measurement cycle which includes mass spectrometric analysis performed one time and MS/MS analysis performed one or more times is repeated. After that, ions originating from the same component are selected based on the retention time of a peak in an extracted ion chromatogram created for each product ion, and the component is identified.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: August 11, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Atsuhiko Toyama, Hideki Yamamoto
  • Patent number: 10733505
    Abstract: Methods for receiving a request to process, on a hardware circuit, a neural network comprising a first convolutional neural network layer having a stride greater than one, and in response, generating instructions that cause the hardware circuit to, during processing of an input tensor, generate a layer output tensor equivalent to an output of the first convolutional neural network layer by processing the input tensor using a second convolutional neural network layer having a stride equal to one but that is otherwise equivalent to the first convolutional neural network layer to generate a first tensor, zeroing out elements of the first tensor that would not have been generated if the second convolutional neural network layer had the stride of the first convolutional neural network layer to generate a second tensor, and performing max pooling on the second tensor to generate the layer output tensor.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: August 4, 2020
    Assignee: Google LLC
    Inventors: Reginald Clifford Young, William John Gulland
  • Patent number: 10643750
    Abstract: A system and method, using one or more dimensions, that assesses the veracity of a diagnosis presently in a health care record is disclosed. The system assesses the veracity of a diagnosis based on a set of dimension values and a set of weightings. The system also provides a user interface to health care providers/caregivers to review the assessment made by the system and may include a feedback mechanism so that the system may adjust the weighting of the dimensions and improve the assessment of the diagnosis made by the system.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 5, 2020
    Assignee: Humana Inc.
    Inventor: Ahmed Ghouri
  • Patent number: 10634653
    Abstract: Systems, methods and devices are taught for providing analytical methods for peak-shaped responses separated in time or space, including quantitation of chromatographic peaks based on a width measurement of a peak trace at a selected height as a quantitation element. Methods of treating a peak trace as a composition of exponential functions representing a leading and a trailing end are included. Methods that facilitate the detection of impurities in peak trace outputs are also included.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: April 28, 2020
    Assignees: Dionex Corporation, Board of Regents, The University of Texas System
    Inventors: Purnendu K. Dasgupta, Akinde F. Kadjo, Kannan Srinivasan
  • Patent number: 10603437
    Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: March 31, 2020
    Assignee: Novo Nordisk A/S
    Inventors: Henrik Bengtsson, Toke Folke Christensen, Louise Wagner Noergaard, Mads Schenstroem Stefansen
  • Patent number: 10569247
    Abstract: The present invention is directed to a high pressure fluidized bed system using dual control valves, and an inner pressure control method thereof. The high pressure fluidized bed system includes a fluidized bed reactor, a pressure sensor which measures a pressure in the interior of the fluidized bed reactor, a cyclone part which is coupled to the fluidized bed reactor, a first valve allowing controlling of the exhaust gas, and a second valve allowing manually controlling of exhaust gas except for the exhaust gas controlled by the first valve. The first valve is capable of opening and closing automatically, and the second valve is capable of opening and closing manually, and are used in combination in the high pressure fluidized bed, allowing decreasing of the pressure variation within the reactor and improving the operation stability of the reactor.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: February 25, 2020
    Assignee: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Ho-Jung Ryu, Doyeon Lee, Sung-Ho Jo, Hyungseok Nam, Gyoung-Tae Jin, Chang-Keun Yi, Dowon Shun, Jaehyeon Park, Dal-Hee Bae, Seung-Yong Lee, Youngcheol Park, Dong-Ho Lee
  • Patent number: 10564037
    Abstract: A method and apparatus for combining colorants using a camera. The method of combining colorants using a camera includes extracting color data from an image of an object captured using a camera, converting the color data into spectral reflection factor data of the object on the basis of a pre-constructed camera color model, acquiring spectral reflection factor data for an estimated colorant combination obtained by simulating a combination of colorant samples obtained from a colorant database, and selecting an optimal colorant combination by comparing errors between the spectral reflection factor data of the object and the spectral reflection factor data for the estimated colorant combination. Therefore, it is possible to use a highly accessible and inexpensive camera, such as a smartphone camera, and thus an ordinary user can easily find an optimal colorant combination.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: February 18, 2020
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: In Su Jang, Soon Chul Jung, Yoon Seok Choi, Jin Seo Kim
  • Patent number: 10551305
    Abstract: The invention relates to a method for determining the origin of a mixture of constituents by spectral analysis. The invention especially relates to a method for determining the concentration and origin of raw gases and/or crude oils in a mixing zone following mixing by the transport of said raw gases and/or crude oils that come from at least two different sources of extraction, said method comprising a specific spectral analysis.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: February 4, 2020
    Assignee: TOPNIR SYSTEMS SAS
    Inventors: Didier Lambert, Claude Saint Martin, Miguel Sanchez, Bernard Ribero
  • Patent number: 10502862
    Abstract: Methods and systems for locating a chemical source include measuring chemical concentration with sensors at a plurality of different positions. Measurements from pairs of positions are cross-correlated to determine an average velocity vector for a group of positions. A convergence region is determined based on a plurality of average velocity vectors to determine a chemical source location.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: December 10, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventor: Bruce G. Elmegreen
  • Patent number: 10448873
    Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: October 22, 2019
    Assignee: DexCom, Inc.
    Inventors: Sebastian Böhm, Daiting Rong, Peter C. Simpson
  • Patent number: 10422781
    Abstract: A dive computer with a free dive mode and/or wireless data transmission capabilities. In one embodiment the invention relates to a diving apparatus including a dive computer having a free dive mode, where the dive computer is configured to calculate a nitrogen loading in the free dive mode using a default value which is the fraction of oxygen in air, and where the free dive mode is used when a diver makes a dive without a self-contained underwater breathing apparatus. Another embodiment includes a method of operating a dive computer including recording two or more first identifiers, receiving pressure information from two or more pressure transmitters, the pressure information comprising second identifiers and pressure measurements, determining whether the pressure information contains one of the two or more first identifiers, and displaying a message indicative of the pressure information that contains one of the two or more first identifiers.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: September 24, 2019
    Assignee: Pelagic Pressure Systems Corp.
    Inventors: Robert R. Hollis, Michael S. Hollis, Jack Calvin Holman
  • Patent number: 10393883
    Abstract: The subject matter disclosed herein relates to determining a background location of a mobile device using one or more signal metrics.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: August 27, 2019
    Assignee: QUALCOMM Incorporated
    Inventors: Marc Anthony Ische, Ahmad Hatami, Ardalan Heshmati, Zoltan F. Biacs, Douglas Neal Rowitch, Dominic Gerard Farmer, Srigouri Kamarsu, Jie Wu
  • Patent number: 10386346
    Abstract: A data processing system for a chromatograph has an impurity detector including a differential chromatogram creator and a determining section. The differential chromatogram creator calculates a wavelength differential coefficient by differentiating an absorbance spectrum with respect to the wavelength at each point in time of the measurement and creates a differential chromatogram which shows a temporal change in the wavelength differential coefficient. Based on a shape of the thus created differential chromatogram, the determining section determines whether or not a peak of a target component contains an impurity. By this method, whether or not the peak of the target component contains an impurity can be determined with high accuracy, without requiring complex calculations.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: August 20, 2019
    Assignee: SHIMADZU CORPORATION
    Inventors: Yasuhiro Mito, Etsuho Kamata, Hiroshi Miura, Kenichi Mishima, Toshinobu Yanagisawa
  • Patent number: 10379234
    Abstract: A gamma-ray analysis system is described for analyzing gamma-ray emitting radionuclides. The gamma-ray analysis system includes an analytical apparatus having a gamma-ray detector in operative communication with a modular and scalable shield assembly that encases a sample container having a sample to be tested. The detector communicates data to an electronic interface device that converts the data from an analog format to a digital format before a controller transmits the data to a central laboratory for further data processing, analysis and conclusion by qualified laboratory analysts. The controller runs an application software package on a graphic user interface that allows simple steps for conducting testing and data acquisition by the end user, while permitting real time data transmission between the field site and the central location. Functions were implemented for ensuring laboratory quality results while removing knowledge and experience requirements of an end user.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: August 13, 2019
    Assignees: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services, Mirion Technologies, Inc., Mirion Technologies (Canberra UK) Limited
    Inventors: Cong Wei, Kelly M. Garnick, Thomas A. Scott, Elon M. Malkin, Jennifer T. Szymanski, Steve Laskos, James Cocks, Jeffrey Raimondi, Richard Mowry, Hiram Gonzalez, Ronald White, Wilhelm Mueller, Robert Fournier
  • Patent number: 10319574
    Abstract: Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: June 11, 2019
    Assignee: Highland Innovations Inc.
    Inventors: Eung Joon Jo, Yohahn Jo
  • Patent number: 10203319
    Abstract: The invention relates to a process for determining the degree of branching of modified polymers wherein the polymers are modified in the sense that their degree of branching after polymerization was increased once more, wherein the modified polymers are treated with a polar transformation mixture comprising a compound of general formula (I) R1—S—S—R1?? (I) wherein the Mooney viscosity (ML 1+4 at 100° C.) of the polymers is determined before and after the treatment with the polar transformation mixture and the degree of branching is determined.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: February 12, 2019
    Assignee: ARLANXEO DEUTSCHLAND GMBH
    Inventors: Heike Kloppenburg, Alicia Le-Sattler
  • Patent number: 10203277
    Abstract: There is provided a technique for automatically determining or predicting a line range specific to a sample that appears in a reaction curve in an automated analyzer for mixing a specimen and a reagent and measuring a change in a mixture of the specimen and the reagent with time. This invention approximates reaction curve data by a function and automatically determines a curve part at an early stage or a second stage of a reaction. The invention determines a line range not including a curve part for each sample and calculates a laboratory test value using absorbance data within the determined line range. This invention also automatically determines a start time of line at the early stage of the reaction on the basis of absorbance data obtained up to a point halfway through the reaction curve, predicts a line range on the basis of the end time of line and a planned end time of line, and calculates a predictive value on the basis of a result of the prediction.
    Type: Grant
    Filed: April 5, 2011
    Date of Patent: February 12, 2019
    Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Chihiro Manri, Satoshi Mitsuyama, Tomonori Mimura, Kumiko Kamihara
  • Patent number: 10190899
    Abstract: A thermal flow sensor with improved measurement accuracy is provided. The thermal flow sensor includes: an air flow rate detection element with a diaphragm having a thin-film portion in a semiconductor substrate; at least one heat generating resistor on the diaphragm; at least one temperature measuring resistor that detects temperature on each of an upstream side and a downstream side of the heat generating resistor; and a correction circuit portion that processes an output signal of the air flow rate detection element on the basis of temperature difference information of at least the two temperature measuring resistors on the upstream side and the downstream side, wherein a waveform of the output signal processed by the correction circuit portion is a waveform obtained by cutting a part of a mountain part or a valley part constituting a peak value by outputting of an arbitrary predetermined value when the peak value of the waveform exceeds the arbitrary predetermined value.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: January 29, 2019
    Assignee: Hitachi Automotive Systems, Ltd.
    Inventors: Ryosuke Doi, Shinobu Tashiro, Kazunori Suzuki, Masahiro Matsumoto
  • Patent number: 10134008
    Abstract: Embodiments of the present invention provide systems and methods for evaluating specification data of two or more components. In one embodiment, informational data, including specifications, provides details on these two or more components. The system then derives a set of interactions within these two or more components. From the informational data, in conjunction with interactions within the two or more components, it is determined whether one or more incompatibility issues exist. In instances where one or more incompatibility issues exist, the issue is highlighted and given a description.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: November 20, 2018
    Assignee: International Business Machines Corporation
    Inventor: Eric V. Kline
  • Patent number: 10060942
    Abstract: Systems and methods for measuring turbulent gas flux using high-speed vertical wind speed measurements (e.g., on the order of 5-10 Hz or more frequently) and low-speed gas content measurements (e.g., on the order of 5 Hz or less frequently), without the need for the sophisticated and expensive high-speed hardware to separate gas samples (e.g., into accumulation bags) according to updrafts and downdrafts. A time series of high-speed vertical wind speed data is used as a guide to distinguish between updrafts and downdrafts. When vertical wind speed is upward (updraft), the low-speed gas content is recorded into a data structure in one location, or marked with one flag. When vertical wind speed is downward (downdraft), the low-speed gas content is recorded into a different location, or marked with a different flag. Eddy Accumulation or Relaxed Eddy Accumulation computations can be performed using the stored gas content data to determine gas flux.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: August 28, 2018
    Assignee: Li-Cor, Inc.
    Inventors: George G. Burba, Dayle McDermitt, Xiaomao Lin, Liukang Xu, Dave Johnson
  • Patent number: 10001462
    Abstract: A method and system for detecting pesticide residue in agricultural products. The system includes a chromatographic and mass-spectrometric system and a computer. The system inspects first and second sample solutions prepared from two identical extracts of an agricultural product. The first sample solution includes no additives while the second sample is added with a pesticide standard which is intended to be detected by the system for comparison. The computer compares the mass chromatograms of the first and second sample solutions, and calculate an increased integral area by which the peak of the second sample solution in the second mass chromatogram exceeds the peak of the first sample solution in the first mass chromatogram at the same retention time. As such, the concentration of pesticide residue in the sample can be determined by a ratio between the increased integral area and the concentration of the pesticide standard.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: June 19, 2018
    Assignee: AGRICULTURAL CHEMICALS AND TOXIC SUBSTANCES RESEARCH INSTITUTE, COUNCIL OF AGRICULTURE, EXECUTIVE YUAN
    Inventors: Shao-Kai Lin, Wei-Chen Chuang
  • Patent number: 9997341
    Abstract: A method of mass spectrometry is disclosed comprising experimentally determining or measuring one or more first ion mobility values, collision cross sections or interaction cross sections collision cross sections or first ion mobility parameters and one or more mass or mass to charge ratios of one or more analyte ions, generating a first list of possible candidate compounds which correspond to said one or more analyte ions on the basis of the one or more determined or measured masses or mass to charge ratios, and calculating, estimating or determining one or more second ion mobility values, collision cross sections or interaction cross sections collision cross sections or second ion mobility parameters of at least some of the candidate compounds in the first list.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: June 12, 2018
    Assignee: MICROMASS UK LIMITED
    Inventors: Martin Raymond Green, Kevin Giles, Keith Richardson, Jason Lee Wildgoose
  • Patent number: 9989505
    Abstract: A system includes a gas chromatograph configured to determine experimental chromatographic data including retention times associated with samples. The system also includes a mass spectrometer configured to determine experimental mass spectral data associated with samples. The mass spectrometer can include a quadrupole field ion trap that uses a non-classical detection technique. The system determines a retention index for an unknown sample based upon retention times for a calibration sample and the unknown sample, and identifies reference mass spectral data using the retention index. The reference mass spectral data can include spectra measured using a classical detection technique. The system can compare the experimental mass spectral data to the reference mass spectral data using one or more comparison metrics, such as a percent fragment match and/or a variance match. A score can be determined to identify the unknown sample using one or more of the metrics.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 5, 2018
    Assignee: SMITHS DETECTION INC.
    Inventors: Charles S. Sadowski, Greger Andersson, Kevin Judge
  • Patent number: 9976997
    Abstract: When there are a plurality of concentration value candidates, an extreme value of the calibration curve is detected, and the number of calibration points respectively contained in a region having a low concentration and a region having a high concentration is calculated using the extreme value as a boundary. If there is a difference between the numbers of calibration points of both regions, a concentration value candidate present in the region having a larger number of calibration points is selected as a quantitation result. When the numbers of calibration points are the same, the sign of the coefficient of the term of the second degree of the calibration curve is assessed, and a concentration value candidate present in a region in which the relationship between peak area values and concentration values is monotonically increasing is selected as a quantitation result.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: May 22, 2018
    Assignee: SHIMADZU CORPORATION
    Inventor: Kazuma Maeda
  • Patent number: 9733214
    Abstract: MRM triggered MRM, where the triggered MRM transitions make use of mobility device parameter values for the same compound, is performed. A plurality of primary MRM transitions are received and stored together with a mobility device parameter value for each transition as an MRM cycle list. Control information instructs a mobility device and a mass spectrometer to interrogate each MRM transition on the MRM cycle list within an MRM cycle of the mass spectrometer. If a product ion intensity value of an MRM transition exceeds a threshold value for a primary MRM transition, a plurality of secondary MRM transitions of the primary MRM transition with different mobility device parameter values are added to the MRM cycle list. The intensities of the measured secondary MRM transitions provide information on the optimum mobility device parameter for each compound.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: August 15, 2017
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Christie L. Hunter, David M. Cox
  • Patent number: 9733227
    Abstract: A dive computer with a free dive mode and/or wireless data transmission capabilities. In one embodiment the invention relates to a diving apparatus including a dive computer having a free dive mode, where the dive computer is configured to calculate a nitrogen loading in the free dive mode using a default value which is the fraction of oxygen in air, and where the free dive mode is used when a diver makes a dive without a self-contained underwater breathing apparatus. Another embodiment includes a method of operating a dive computer including recording two or more first identifiers, receiving pressure information from two or more pressure transmitters, the pressure information comprising second identifiers and pressure measurements, determining whether the pressure information contains one of the two or more first identifiers, and displaying a message indicative of the pressure information that contains one of the two or more first identifiers.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: August 15, 2017
    Assignee: Pelagic Pressure Systems Corp.
    Inventors: Robert R. Hollis, Michael S. Hollis, Jack Calvin Holman
  • Patent number: 9464983
    Abstract: A concentration determination apparatus may determine a concentration of a target component in an arbitrary layer of an observed object including a plurality of light scattering medium layers. The concentration determination apparatus may include an irradiation unit, light scattering medium layer selection unit, a light receiving unit, a light intensity acquisition unit, an optical absorption coefficient calculation unit, and a concentration calculation unit.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: October 11, 2016
    Assignees: SEIKO EPSON CORPORATION, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Kazuhiko Amano, Koichi Shimizu
  • Patent number: 9431224
    Abstract: When performing an automatic MS2 analysis on a specimen containing components that include elements whose abundance ratio of stable isotopes is close, to prevent the same component that includes isotopes of differing masses to be successively selected as a precursor ion and allow the MS2 analysis of various components whose retention time to elution is close. As precursor selection conditions, the user is allowed to set in advance the time period for automatic exclusion and a m/z range (?p, q) with respect to any m/z. When the analysis is performed, a precursor selection unit selects a precursor according to a predetermined selection condition for the MS spectrum that was obtained and repeats the MS2 analysis on the precursor ion (m/z=M) for the number of times that is set. Thereafter, for a specified automatic exclusion period, ions falling in a m/z range of M?p to M+q are excluded from selection as a precursor.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: August 30, 2016
    Assignee: SHIMADZU CORPORATION
    Inventor: Shigenobu Nakano
  • Patent number: 9399289
    Abstract: A robot control apparatus, which controls motions of an industrial robot based on processing results of an image processing apparatus which images the robot or objects around the robot, includes: a first communication unit which communicates with a computer for development as an external computer; a second communication unit which is connected to the image processing apparatus via a network; and a command processing unit which opens a communication port of the second communication unit and causes the second communication unit to start communication with the image processing apparatus via a server on the network in response to an open command received by the first communication unit.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: July 26, 2016
    Assignee: Seiko Epson Corporation
    Inventor: Nobuyuki Setsuda
  • Patent number: 9280516
    Abstract: The present invention provides a method and system using wireless sensors to validate wired sensors used in applications where the requirements on the reliability of wired sensors are stringent. A computing means periodically collects measurements for each variable from the wired and wireless sensors and compares them against an expected value. The expected value is a weighted average of all the measurements for a variable, in which the weight assigned to the measurement from each sensor is determined according to both its reliability and accuracy. As such, measurements are compared with the corresponding expected value for a particular variable. If the difference between a measurement and its corresponding expected value is found to be unacceptable, the validation computer will generate a corresponding alert. Application examples include 1) validating wired sensors used in safety shutdown systems for industrial facilities and 2) validating wired sensors used to monitor storage tanks.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: March 8, 2016
    Assignee: THE UNIVERSITY OF WESTERN ONTARIO
    Inventors: Jin Jiang, Qingfeng Li
  • Patent number: 9222873
    Abstract: An optical device mounted on the interior of an aircraft for distinguishing the morphology of individual atmospheric particles, identifying them as water droplets, ice crystals, dust particles or volcanic ash, including a source of collimated, polarized light and providing this information to the flight crew to assist them in making informed decisions on conditions that might impact aircraft performance.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: December 29, 2015
    Assignee: Droplet Measurement Technologies, Inc.
    Inventors: Darrel Baumgardner, Roy Newton
  • Patent number: 9207119
    Abstract: A spectral feature of a pulsed light beam produced by an optical source is estimated by modifying the wavelength of the pulsed light beam based on a predefined repeating pattern having a pattern period including a plurality of steps, the modification including shifting the wavelength of the pulsed light beam by a wavelength offset from a baseline wavelength for each step in the pattern period; measuring the wavelength of the light beam for each step in the pattern period as the wavelength is modified across the pattern; and estimating a spectral feature of the pulsed light beam over an evaluation window that includes all of the steps within the pattern period based at least in part on the measured wavelength of the light beam for each step in the pattern period.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 8, 2015
    Assignee: Cymer, LLC
    Inventors: Rostislav Rokitski, Nakgeuon Seong, Kevin O'Brien
  • Patent number: 9140677
    Abstract: In exemplary implementations of this invention, an electronic olfactor determines whether a scent being tested matches the scent of a positive control. The electronic olfactor can perform this scent matching even in a changing olfactory environment, and even if the positive control scent is a combination of hundreds or thousands of different odorants. No prior training is needed, and no attempt is made to identify a single odorant that is unambiguously responsible for a scent. Instead, a computer compares the total scent pattern of a positive control sample with the total scent pattern of a test sample, across a sweep of many permutations of electrical inputs to scent sensors, to try to find any condition under which the total scent patterns do not match. If such a condition cannot be found, then the computer declares a match between the test and target scents.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: September 22, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Andreas Mershin, Asmamaw Wassie, Yael Maguire, David Kong, Shuguang Zhang, Patrick Moran, Karolina Corin
  • Patent number: 9112474
    Abstract: An RC filter that is tunable in terms of its cut-off frequency comprising a drop placed on one or more dielectric layers, a conducting layer underneath the dielectric layer, a nonconducting layer underneath the conducting layer, and an external resistor attached to the drop via an electrode, wherein the cut-off frequency of the filter is tuned by changing the shape or composition of the drop and methods of using the filter as a detector.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: August 18, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Daniel W. Armstrong, Yasith S. Nanayakkara, Hyejin Moon
  • Patent number: 9043162
    Abstract: A method and apparatus for acquiring data from a mass spectrometer and its transmission to a computer system including a data acquisition engine, a network interface and a throughput optimization module which includes a ring buffer and a protocol stack. A compression engine may be provided between the acquisition engine and the ring buffer. The ring buffer is configured as a number of segments containing portions of memory matching the size of data words from the acquisition engine. When a segment is full of data corresponding to the words, or is partially full and has received data containing an end of scan marker, the number of words in the segment is written into a header word in the segment and the data in that segment are moved to the protocol stack. Subsequent data is received by the next segment in the buffer.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: May 26, 2015
    Assignee: Micromass UK Limited
    Inventors: Peter Gerard Spreadbury, Stephen John Platt
  • Patent number: 9037418
    Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: May 19, 2015
    Assignee: General Electric Company
    Inventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
  • Patent number: 9034594
    Abstract: A method for verifying carbon storage in seawater to which a growth stimulant has been supplied for stimulating a bloom of nitrogen fixing organisms for enhancing carbon storage therein, comprises selecting a region of seawater including a surface mixed layer, a euphotic zone extending below the surface mixed layer, and a plurality of deeper zones; determining the effect of growth stimulant on the rate of nitrogen fixation and carbon transport in the region; and determining the amount of carbon stored at different depths and projected duration of carbon storage at each of the depths.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: May 19, 2015
    Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Anthony Michaels, Sergio Sanudo-Wilhelmy, Douglas Capone, James Moffett
  • Patent number: 9023651
    Abstract: The invention relates to a method and a device (100) for determining the amount of a target component (2) in a sample, wherein magnetic particles (2) can bind to a contact surface (4) with kinetics that depend on the sample-amount of the target component. The method comprises at least two washing steps during which magnetic particles (2) are magnetically moved away from the contact surface (4) and corresponding measurements of the remaining amount of magnetic particles (2) at the contact surface (4). The amount of target component in the sample is estimated from at least one of such measurement results. The measurement allows to determine also high concentrations of target component for which the sensor surface (4) is saturated in a steady-state.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: May 5, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Toon Hendrik Evers, Wendy Uyen Dittmer
  • Patent number: 9020764
    Abstract: The concept underlying the invention is the development of a generic method for the detection and identification of gases in airplane interior spaces and an associated device, which is small and manageable, has a simple design, and allows the immediate and simultaneous detection and identification of the gases to be examined. This is achieved in that the supply air of the airplane interior space (20) is fed to a measuring device (1) and the measurement results of the measuring device (1) are analyzed by means of mathematical methods. Such methods and the associated devices for the detection and identification of gases in airplane interior spaces are used in order to spot and verify gases, particularly odors and explosive gases and/or gases harmful to people's health.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: April 28, 2015
    Assignee: Airsense Analytics GmbH
    Inventors: Andreas Walte, Wolf Münchmeyer, Mario Schmidt
  • Patent number: 9014990
    Abstract: By accurately estimating the survival cell count in a probiotic product, the time for developing the product can be shortened. In a device (1) for estimating survival cell count, a calculation unit (14) calculates an estimated result of the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I). (I) Log10nt=Log10n0?t×EXP{(AT×T+BT)w+(CT×T+DT)}, provided that t stands for the storage period (days)× 1/30, nt stands for the survival cell count (CFU/g) of the strain contained in the composition after the storage period t (days), n0 stands for the viable cell count (CFU/g) of the strain contained in the composition at the initiation of storage, T stands for the storage temperature (° C.), w stands for the water activity value of the composition, AT and CT stand for experimentally determined coefficients specific to the strain, and BT and DT stand for experimentally determined constants specific to the strain.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: April 21, 2015
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Fumiaki Abe, Ayako Uchijima, Masamichi Muto, Ayako Horigome
  • Publication number: 20150106030
    Abstract: Endotoxin detection systems and corresponding detection methods integrate an optical path detection system based on a conventional laser particle size detector and detect the particle size distribution characteristics of the endotoxin colloidal particles in an aqueous solution by using laser light scattering. One system calculates the concentration of the endotoxin by fitting the correlation of the astigmatism with the concentration of the endotoxin based on scattering intensity of the endotoxin particles at more than three different angles via a quantitative operator.
    Type: Application
    Filed: June 13, 2013
    Publication date: April 16, 2015
    Applicant: NANJING TUOZHU PHARMACEUTICAL & TECH CO., LTD
    Inventor: Guoping Peng
  • Publication number: 20150106027
    Abstract: A system and a method for applying 13C or 1H NMR spectroscopy to a sample of crude oil in order to calculate the cetane number, pour point, cloud point, aniline point and octane number of a gas oil fraction of the crude oil.
    Type: Application
    Filed: February 15, 2012
    Publication date: April 16, 2015
    Inventors: Omer Refa Koseoglu, Adnan Al-Hajji, Mohammed Abdullah Al-Ghamdi, Alexander Rebrov
  • Publication number: 20150106028
    Abstract: A system, method and computer program product are provided for calculating the cetane number, octane number, pour point, cloud point and aniline point of crude oil fractions from the density and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) of a sample of the crude oil.
    Type: Application
    Filed: May 9, 2012
    Publication date: April 16, 2015
    Inventors: Omer Refa KOSEOGLU, Adnan Al-Hajji, Hendrik Muller, Hanadi H. Jawad
  • Publication number: 20150106031
    Abstract: A system and a method for calculating the cetane number, pour point, cloud point and aniline point of a gas oil fraction of a crude oil from the density and near infrared spectroscopy of a sample of the crude oil.
    Type: Application
    Filed: February 15, 2012
    Publication date: April 16, 2015
    Inventors: Omer Refa Koseoglu, Adnan Al-Hajji, Anaam Al-Shaikh Ali
  • Publication number: 20150106029
    Abstract: A system and a method are provided for calculating the cetane number, octane number, pour point, cloud point and aniline point of a crude oil fractions from the density and high pressure liquid chromatography (HPLC) of a sample of the crude oil.
    Type: Application
    Filed: May 10, 2012
    Publication date: April 16, 2015
    Inventors: Omer Refa KOSEOGLU, Adran AL-HAJJI, Saroj Kumar PANDA
  • Patent number: 9007073
    Abstract: Provided are a method of measuring a degree of degradation of a lubricating oil and a measuring device therefor, in which (a) acidity is measured through use of an ISFET of hydrogen ion sensitive type and (b) dielectric constants or electrostatic capacitances at two or more different frequencies are obtained, to thereby determine a degradation state of the lubricating oil based on the acidity and a plurality of values of the dielectric constants or the electrostatic capacitances. Accordingly, the degree of degradation of the lubricating oil can be measured easily and precisely and a degradation mechanism of the lubricating oil can be predicted.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: April 14, 2015
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventor: Tadashi Katafuchi
  • Publication number: 20150090872
    Abstract: A hardware module which operatively carries out a method of compressing mass spectral data, the method comprising: receiving a first signal output from an ion detector of a mass spectrometer; processing the first signal to a digital signal at an output being data frame types representative of the first signal output; temporarily storing the data frame types in a memory block and reading a data frame from the memory block and determining its data frame type and according to its data frame type compressing the data frame according to one or more compression algorithms to generate a compressed data output stream.
    Type: Application
    Filed: March 28, 2013
    Publication date: April 2, 2015
    Inventors: Stephen John Platt, Keith George Richardson, Darrell Williams, Richard Denny