Quantitative Determination (e.g., Mass, Concentration, Density) Patents (Class 702/23)
  • Patent number: 11662325
    Abstract: Embodiments herein include a kinetic response system for measuring analyte presence on a chemical sensor element. The chemical sensor element includes one or more discrete binding detectors, each discrete binding detector including a graphene varactor. The kinetic response system includes a measurement circuit having an excitation voltage generator for generating a series of excitation cycles over a time period. Each excitation cycle includes delivering a DC bias voltage to the discrete binding detectors at multiple discrete DC bias voltages across a range of DC bias voltages. The kinetic response system includes a capacitance sensor to measure capacitance of the discrete binding detectors resulting from the excitation cycles. The kinetic response system includes a controller circuit to determine the kinetics of change in at least one of a measured capacitance value and a calculated value based on the measured capacitance over the time period. Other embodiments are also included herein.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: May 30, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Gregory J. Sherwood, Justin Theodore Nelson, Steven J. Koester
  • Patent number: 11614548
    Abstract: Methods and apparatus for calibrating radioactive sources are described. An array of scintillation detectors form a receptacle within which a sample or sample container can be retained by a holder. The scintillation detectors are coupled via light transducers such as photomultiplier tubes (PMTs) to independent electronic counters. Coincidence processing of time-tagged events yields a correlated event rate. One or more corrections can be applied as needed, for background counts, deadtime, or random coincidences. Voltage tuning of PMTs yields improved reproducibility. Variations are disclosed. 1% accuracy has been demonstrated over a range of 10 kBq-3 MBq, covering a gap in the capabilities of conventional technology.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: March 28, 2023
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventor: Stephen S. Adler
  • Patent number: 11561324
    Abstract: Systems and methods for measuring gas flux are provided. The method includes obtaining one or more of wind speed data, gas content data, temperature data and humidity data over a period of time, computing a plurality of different gas flux values for said period of time using a corresponding plurality of different flux calculation algorithms, wherein each of the plurality of different flux calculation algorithms uses one, some or all of the measured data types to calculate gas flux values for one or a plurality of sub-periods of said period of time, and for each of the one or the plurality of sub-periods, determining an optimal flux calculation algorithm of the plurality of different flux calculation algorithms based on one or more quality indicators; and outputting, for each of the plurality of sub-periods, one or more optimal flux calculation values corresponding to the optimal flux calculation algorithm for the sub-period.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: January 24, 2023
    Assignee: Li-Cor, Inc.
    Inventor: George Burba
  • Patent number: 11498858
    Abstract: Embodiments of the invention comprise methods and systems for optimizing coagulant dosing of raw water in a water treatment process. First, the embodiments determine the optimum dosage of pH adjusting chemicals to be added to the raw water based on a measurement of dissolved organic content, alkalinity, and pH of the raw water. Then, the embodiments perform a flocculation test of a mixture of the optimally-pH-dosed raw water and a hydrolyzing metal salt (HMS) wherein the dosage of the HMS salt in the mixture can be calculated based on a measurement of the charge demand of the optimally-pH-dosed raw water. The results of this flocculation test are compared to the results of at least one previous test of a combination of optimally-pH-dosed raw water and HMS to determine if the hydrolyzing metal salt dose is optimized.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: November 15, 2022
    Assignee: Clearcorp
    Inventors: Roger Miles Jorden, Bert Vermeulen
  • Patent number: 11420148
    Abstract: Provided is a system for a spraying booth, including a spraying booth and at least one filter with at least one VOC detector, the system further including a central database where at least data of the VOC detector are stored, whereby is achieved that the value of the measurements can be accessed and controlled centrally, either by the customer's own technicians or by the supplier's technicians, by a communication unit.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: August 23, 2022
    Assignee: HURIYA PRIVATE FZLLE
    Inventor: Henrik Bro Christensen
  • Patent number: 11398373
    Abstract: A method of controlling the operation of an ion mobility separation device is disclosed. The method comprises displaying to a user via a user interface a pool of modes of operation of the ion mobility separation device, wherein each one of the modes is selectable by the user for inclusion in an experiment, and the modes are displayed in a first area 202 of the user interface. The method comprises receiving, via the user interface, an indication from the user of a selection of one or more instance of each one of a plurality of the modes from the pool to be included in an experiment, and an indication from the user of a set of one or more parameters for controlling the ion mobility separation device in respect of one or more selected instances of a mode. The selected instances of modes are displayed in a sequence in a second area 204 of the user interface. The operation of the ion mobility separation device is controlled in accordance with the received indications.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: July 26, 2022
    Assignee: Micromass UK Limited
    Inventors: Sandra Richardson, Keith George Richardson, Kevin Giles, Jakub Ujma
  • Patent number: 11391684
    Abstract: The present disclosure relates to a method for measuring aromatic contents in a hydrocarbon solution. More specifically, it relates to a measurement method capable of quickly and accurately checking aromatic contents in a compound, particularly in a hydrocarbon, in a solution state without a high-temperature drying process.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: July 19, 2022
    Assignee: HANWHA SOLUTIONS CORPORATION
    Inventors: Yong Hee Lee, Wan Jae Myeong, Woo Jin Park, Bong Sik Jeon, Eui Geun Jung
  • Patent number: 11385379
    Abstract: A method and apparatus detects an unknown deposit in soil of a known mineral or gemstone using characteristic scents of the mineral or gemstone. The method may disturb the soil, for example, by causing a chemical reaction in at least part of the soil such that a mineral or gemstone present in the soil emits a characteristic scent. The unknown deposit of the known mineral or gemstone can be detected in real-time or near real-time in the field.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: July 12, 2022
    Inventor: Peter J. Wilk
  • Patent number: 11380532
    Abstract: In an imaging mass spectrometer for analyzing the same kind of samples using results of imaging mass spectrometric analysis performed on those samples, a measurement section (1) acquires mass spectrometric data by performing an analysis on each of the micro areas on a sample. A region-of-interest setter (32) sets an ROI on each sample, and divides each ROI into the same number of subregions each including the micro areas so that the subregions correspond to each other on the samples respectively covering roughly identical sites on the samples. An individual-index-value calculator (33) calculates an individual index value for each subregion, using mass spectrometric data acquired at the micro areas in the subregion, the individual index value reflecting a similarity or difference among the samples in terms of a degree of expression of each m/z value.
    Type: Grant
    Filed: March 30, 2021
    Date of Patent: July 5, 2022
    Assignee: SHIMADZU CORPORATION
    Inventor: Shinichi Yamaguchi
  • Patent number: 11336868
    Abstract: The device recording the collisions of flying animals with wind turbines and indicating where they fell on the ground includes at least two sensors arranged on at least two different heights of the wind turbine tower. The sensors have a range optimally in a direction perpendicular to the wind turbine tower and are connected with the control and recording unit by wire or wireless data transmission.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: May 17, 2022
    Inventor: Michal Przybycin
  • Patent number: 11328916
    Abstract: A method of determining mass defect plots with user-defined mass scaling, filtering, and labeling in a mass spectrometer is described. An implementation of the method comprises, (i) generating a mass defect plot from the data, (ii) filtering all ions in the mass defect plot that do not have an associated isotopologue ion, (iii) selecting an unidentified ion, (iv) determining an isotope pattern of the unidentified ion, (v) identifying one or more elements indicated by the isotope pattern for the unidentified ion; (vi) searching formulas containing one or more elements indicated by the isotope pattern for the unidentified ion, (vii) determining a chemical formula of the identified ion, and (viii) displaying the chemical formulas for the unidentified ion on a screen.
    Type: Grant
    Filed: March 5, 2017
    Date of Patent: May 10, 2022
    Assignee: LECO Corporation
    Inventors: Jonathan David Byer, Kevin Matthew Siek
  • Patent number: 11280242
    Abstract: A method for controlling an exhaust aftertreatment system for vehicles includes: determining, by a controller, whether or not a designated regeneration operation is finished; accumulating, by the controller, a first amount of NOx emission measured by a rear end NOx sensor of an selective catalytic reduction (SCR) apparatus and a second amount of NOx emission calculated by an NOx emission amount model respectively for a first reference period of time immediately after the regeneration operation is finished; determining, by the controller, whether or not a difference between an accumulated value of the first amount of NOx emission and an accumulated value of the second amount of NOx emission exceeds a reference value when the first reference period of time has elapsed; and correcting, by the controller, a model purification efficiency using a sensor purification efficiency when the difference between the accumulated values exceeds the reference value.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: March 22, 2022
    Assignees: HYUNDAI MOTOR COMPANY, KIA MOTORS CORPORATION
    Inventor: Min Jae Kim
  • Patent number: 11282102
    Abstract: Provided is a method for providing a reward based on consumption of content performed by a computing device. The method comprises querying a user terminal located in a first space by using location information of a first space, measuring the number of users located in the first space according to the number of the queried user terminals and a first content playback record and calculating a first reward for the first content by using the measured number of users and the first content playback record, and providing the first reward to an account of a producer linked to a producer terminal of the first content.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: March 22, 2022
    Inventor: Sang Hyun Shin
  • Patent number: 11226319
    Abstract: A method of use encompassing coded sampling containers that may be implemented in two phases, the results of which may be further processed to arrive at a final score. The first phase incorporates four sampling containers in the context of a series of triangle tests to arrive at a first subscore. The second phase uses two of the coded containers and requires the participants to assess the degree to which the contents of the containers reflect a particular characteristic on a scale. The responses of each participant may be scored by summing the differences between the actual answers and the correct answers to arrive as a second subscore. A final score may be calculated by subtracting the first subscore from the second subscore.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: January 18, 2022
    Inventor: Aimée Sunseri
  • Patent number: 11209406
    Abstract: A data processing device that processes three-dimensional data having time, intensity, and wavelength collected from a sample serving as a measurement target includes: a chromatogram generator configured to generate a chromatogram from the three-dimensional data; a target peak determiner configured to determine a target peak from peaks appearing on the chromatogram; a time point specifier configured to specify a time point at which the size of a spectrum matches the size of a reference spectrum from a time range during which the target peak appears in the three-dimensional data; and a target spectrum generator configured to extract data at the time point from the three-dimensional data, thereby generating a spectrum at the time point. With this configuration, a spectrum that is not affected by distortion, saturation, or noise can be readily and reliably obtained from the three-dimensional data obtained through sample analysis.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: December 28, 2021
    Assignee: Shimadzu Corporation
    Inventors: Toshinobu Yanagisawa, Kanta Horie
  • Patent number: 11156530
    Abstract: A system and method for verifying a mechanical system chip detection capability, the method including determining a slurry injection location in machinery according to a targeted obstruction in the machinery in relation to a target chip detector of the machinery, placing an injection tube through a machinery casing of the machinery, providing a slurry tube connected to the injection tube, the slurry tube containing a slurry comprising conductive chips and a lubricant, operating the machinery until the machinery meets one or more predetermined operating parameters, injecting the slurry into the machinery casing during operation of the machinery and after the machinery meets the one or more predetermined operating parameters, and monitoring the target chip detector for detection of the conductive chips during the operation of the machinery.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: October 26, 2021
    Assignee: TEXTRON INNOVATIONS INC.
    Inventors: Steven R. Quick, Cyrus Elliott Rahimzadeh
  • Patent number: 11125765
    Abstract: An automatic analyzer allows identification of the patient specimen for which the specific reagent and the standard solution have been used, and verification of reliability of the analysis results. A plot mark 1-10 is determined depending on whether or not codes and lots as management information of the reagent, standard solution, and accuracy control sample are the same as those used last time. The plot 1-3 represents the start of using the reagent, and 1-4 the reagent use area. The plot 1-5 represents generation of calibration curve data from the standard solution and 1-6 a standard solution use area. The plot 1-7 represents measurement of the accuracy control sample and 1-8 an accuracy control sample use area from a time point of measuring the accuracy control sample as indicated by the plot 1-7 until the next time point. The measurement information 1-14 is the region for displaying the measurement results.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: September 21, 2021
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventor: Hiroki Mori
  • Patent number: 11105781
    Abstract: In one aspect, a method for detecting the labelling state of unknown species of molecules M contained in a sample exposed to a non-changing isotope labelling process using mass spectrometry is described.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: August 31, 2021
    Assignee: Thermo Fisher (Bremen) GmbH
    Inventor: Martin Strohalm
  • Patent number: 11106977
    Abstract: Systems and methods for training models across multiple sensing units in a chemical sensing system are described. The chemical sensing system comprises at least one computer processor and at least one computer readable medium including instructions that, when executed by the at least one computer processor, cause the chemical sensing system to perform a training process. The training process comprises accessing a training dataset including first values representing first signals output from a first chemical sensing unit of multiple chemical sensing units, and second values representing second signals output from a second chemical sensing unit of the multiple chemical sensing units, and training a set of models to relate the first values and the second values to a mutual latent representation using the training dataset.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: August 31, 2021
    Assignee: Stratuscent Inc.
    Inventors: Mojtaba Khomami Abadi, Amir Bahador Gahroosi, Ashok Prabhu Masilamani, Neven Maric
  • Patent number: 11100264
    Abstract: A computer platform implements a precision agriculture system that predicts output conditions, such as diseases, salt damage, soil problems, water leaks and generic anomalies, for orchards under analysis. The computer platform stores site and crop datasets and processed satellite image for the orchards. An orchard data learned model predicts a propensity for existence of output conditions associated with the permanent crops based on the data values for the variables of the site and crop datasets. Also, a satellite model predicts a propensity for existence of the output conditions at the orchard based on processed satellite images. A precision agriculture management model is disclosed that integrates the orchard data learned model with the satellite model to accurately predict the output conditions.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: August 24, 2021
    Inventor: Harris Lee Cohen
  • Patent number: 11061006
    Abstract: A review image is displayed prior to measurement of an analysis target sample. The review image includes a waveform image and a numerical value image showing a measurement condition determined for a measurement segment of interest. The waveform image includes a waveform portion which is a part of a chromatogram, and a marker array showing a period of a circulating ion measurement. The marker array includes a plurality of markers which are displayed in an overlapping manner over the waveform portion.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: July 13, 2021
    Assignee: JEOL Ltd.
    Inventor: Masako Ota
  • Patent number: 11015987
    Abstract: A temperature estimation method estimating a temperature of a heat generating site in an oil-immersed electric appliance immersed in insulating oil, the insulating oil being silicone oil or ester oil. The temperature estimation method includes measuring concentrations of two types of thermal decomposition products in the insulating oil and calculating a temperature of the heat generating site in the oil-immersed electric appliance based on a concentration ratio between the two types of thermal decomposition products and a relational expression between the temperature of the heat generating site and the concentration ratio prepared in advance. When the silicone oil is adopted as the insulating oil, at least one of the two types of thermal decomposition products is straight-chain siloxane, alcohol containing silicon, or benzene. When the ester oil is adopted as the insulating oil, the two types of thermal decomposition products are fatty acids.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: May 25, 2021
    Assignee: MITSUBISHI ELECTRIC CORPORATION
    Inventors: Kota Mizuno, Satoru Toyama, Ryuichi Nishiura, Tsuyoshi Amimoto, Ryota Kuriyama
  • Patent number: 10989642
    Abstract: Disclosed is an apparatus for and a method of mass analysis in which a presence of an accessory substance which is difficult to be analyzed can be recognized visually and clearly. The apparatus for mass analysis analyzes a sample containing a substance to be measured and includes: a display unit; a memory unit storing a theoretical peak obtained by calculation with respect to a region of a mass spectrum of the substance; a matching degree calculation unit calculating a matching degree from multiple peaks that each of the mass spectrum of the sample in the region and the theoretical peak have; a matching degree displaying control unit displaying the matching degree on the display unit; and a superimposition displaying control unit displaying the mass spectrum of the sample and the theoretical peak in a superimposed way in a manner that is consistent with a mass-to-charge ratio.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: April 27, 2021
    Assignee: HITACHI HIGH-TECH SCIENCE CORPORATION
    Inventor: Masahiro Sakuta
  • Patent number: 10935692
    Abstract: Methods and systems for locating a chemical source include cross-correlating chemical concentration data from pairs of positions using a processor to determine an average velocity vector for a group of positions that averages away turbulence contributions. A convergence region is determined based on multiple average velocity vectors to determine a chemical source location.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: March 2, 2021
    Assignee: International Business Machines Corporation
    Inventor: Bruce G. Elmegreen
  • Patent number: 10935679
    Abstract: The present disclosure discloses a coupling evaluation geophone, comprising piezoelectric ceramic crystal 1, 2 and 3, a geophone 4 and a relevant supplying circuit. Three piezoelectric ceramic crystals 1, 2 and 3 are respectively provided on the top and two lateral sides of the geophone 4. By processing measurement data derived from the coupling evaluation geophone, a ground-geophone coupling effect is obtained at a corresponding embedment point of the coupling evaluation geophone. An effect of the ground-geophone coupling on an earthquake data can be eliminated by calculation. Data detected by the coupling evaluation geophone is improved in fidelity, Signal/Noise ratio and resolution.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: March 2, 2021
    Inventor: Jidong Wei
  • Patent number: 10910205
    Abstract: Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: February 2, 2021
    Assignee: Highland Innovations Inc.
    Inventors: Eung Joon Jo, Yohahn Jo
  • Patent number: 10825672
    Abstract: Techniques and apparatus for analyzing mass spectrometry data are described. In one embodiment, for example, an apparatus may include logic to access a product ion data set generated via mass analyzing a sample comprising a target precursor, access precursor composition information for elements of the target precursor that includes nominal mass and mass defect information, determine nominal mass (NM)-mass defect (MD) relationship information for ion fragments associated with the target precursor based on the precursor composition information, determine one or more fragment upper boundaries and one or more fragment lower boundaries, extract candidate ion fragments from the ion fragments via applying the one or more fragment upper boundaries and the one or more fragment lower boundaries to the NM-MD relationship information, and determine target ion fragments from the plurality of candidate ion fragments based on fragmentation efficiency information associated with the candidate ion fragments.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: November 3, 2020
    Assignee: WATERS TECHNOLOGIES CORPORATION
    Inventors: Scott J. Geromanos, Curt Devlin, Steven J. Ciavarini
  • Patent number: 10802005
    Abstract: A chromatogram data processing system having an impurity detector including a differential chromatogram creator, a purity curve creator and a determiner. The differential chromatogram creator calculates a differential coefficient of an absorbance spectrum with respect to wavelength at a local maximum or local minimum absorption wavelength of the target component, and creates a differential chromatogram which shows a temporal change of the differential coefficient. The purity curve creator creates a purity curve which shows a temporal change of the difference between the degree of similarity of a spectrum on the target peak to a reference spectrum and a threshold of the degree of similarity which is determined taking into account the influence of noise components. The differential chromatogram and the purity curve are displayed on a display unit in a superposed form on a wavelength chromatogram created by a wavelength chromatogram creator.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: October 13, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Kenichi Mishima, Etsuho Kamata, Hiroshi Miura, Yasuhiro Mito, Toshinobu Yanagisawa
  • Patent number: 10794880
    Abstract: Sequential identification numbers are automatically provided and undisplayed, constant, unique numbers are assigned to each event registered in an analysis condition setting table 100. Since correspondence information between the identification numbers and the unique numbers changes due to the reassignment of identification numbers when an event is deleted from the table, event identification numbers for each compound are changed by referring to the correspondence information on a compound information table. As a result, it is possible to avoid the misalignment of event identification numbers between both tables. In addition, when an instruction is given to coordinate the time information or m/z information on both tables, the information on one table is reflected on the other table in accordance with the identification numbers.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: October 6, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Yutaro Yamamura, Tohru Shiohama, Yuji Katsuyama
  • Patent number: 10741372
    Abstract: As soon as a set of data is acquired by a mass spectrometric analysis, an accumulated value of the signal intensity on the mass spectrum is calculated for each m/z segment obtained by dividing the entire m/z range covered by the measurement by a predetermined m/z width. Only the m/z segments with accumulated signal-intensity values equal to or greater than a predetermined threshold are selected as the target for an MS/MS analysis. MS/MS analysis is performed for each selected m/z segment, using ions whose m/z values fall within the m/z segment as precursor ions. A measurement cycle which includes mass spectrometric analysis performed one time and MS/MS analysis performed one or more times is repeated. After that, ions originating from the same component are selected based on the retention time of a peak in an extracted ion chromatogram created for each product ion, and the component is identified.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: August 11, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Atsuhiko Toyama, Hideki Yamamoto
  • Patent number: 10733505
    Abstract: Methods for receiving a request to process, on a hardware circuit, a neural network comprising a first convolutional neural network layer having a stride greater than one, and in response, generating instructions that cause the hardware circuit to, during processing of an input tensor, generate a layer output tensor equivalent to an output of the first convolutional neural network layer by processing the input tensor using a second convolutional neural network layer having a stride equal to one but that is otherwise equivalent to the first convolutional neural network layer to generate a first tensor, zeroing out elements of the first tensor that would not have been generated if the second convolutional neural network layer had the stride of the first convolutional neural network layer to generate a second tensor, and performing max pooling on the second tensor to generate the layer output tensor.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: August 4, 2020
    Assignee: Google LLC
    Inventors: Reginald Clifford Young, William John Gulland
  • Patent number: 10643750
    Abstract: A system and method, using one or more dimensions, that assesses the veracity of a diagnosis presently in a health care record is disclosed. The system assesses the veracity of a diagnosis based on a set of dimension values and a set of weightings. The system also provides a user interface to health care providers/caregivers to review the assessment made by the system and may include a feedback mechanism so that the system may adjust the weighting of the dimensions and improve the assessment of the diagnosis made by the system.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 5, 2020
    Assignee: Humana Inc.
    Inventor: Ahmed Ghouri
  • Patent number: 10634653
    Abstract: Systems, methods and devices are taught for providing analytical methods for peak-shaped responses separated in time or space, including quantitation of chromatographic peaks based on a width measurement of a peak trace at a selected height as a quantitation element. Methods of treating a peak trace as a composition of exponential functions representing a leading and a trailing end are included. Methods that facilitate the detection of impurities in peak trace outputs are also included.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: April 28, 2020
    Assignees: Dionex Corporation, Board of Regents, The University of Texas System
    Inventors: Purnendu K. Dasgupta, Akinde F. Kadjo, Kannan Srinivasan
  • Patent number: 10603437
    Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: March 31, 2020
    Assignee: Novo Nordisk A/S
    Inventors: Henrik Bengtsson, Toke Folke Christensen, Louise Wagner Noergaard, Mads Schenstroem Stefansen
  • Patent number: 10569247
    Abstract: The present invention is directed to a high pressure fluidized bed system using dual control valves, and an inner pressure control method thereof. The high pressure fluidized bed system includes a fluidized bed reactor, a pressure sensor which measures a pressure in the interior of the fluidized bed reactor, a cyclone part which is coupled to the fluidized bed reactor, a first valve allowing controlling of the exhaust gas, and a second valve allowing manually controlling of exhaust gas except for the exhaust gas controlled by the first valve. The first valve is capable of opening and closing automatically, and the second valve is capable of opening and closing manually, and are used in combination in the high pressure fluidized bed, allowing decreasing of the pressure variation within the reactor and improving the operation stability of the reactor.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: February 25, 2020
    Assignee: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Ho-Jung Ryu, Doyeon Lee, Sung-Ho Jo, Hyungseok Nam, Gyoung-Tae Jin, Chang-Keun Yi, Dowon Shun, Jaehyeon Park, Dal-Hee Bae, Seung-Yong Lee, Youngcheol Park, Dong-Ho Lee
  • Patent number: 10564037
    Abstract: A method and apparatus for combining colorants using a camera. The method of combining colorants using a camera includes extracting color data from an image of an object captured using a camera, converting the color data into spectral reflection factor data of the object on the basis of a pre-constructed camera color model, acquiring spectral reflection factor data for an estimated colorant combination obtained by simulating a combination of colorant samples obtained from a colorant database, and selecting an optimal colorant combination by comparing errors between the spectral reflection factor data of the object and the spectral reflection factor data for the estimated colorant combination. Therefore, it is possible to use a highly accessible and inexpensive camera, such as a smartphone camera, and thus an ordinary user can easily find an optimal colorant combination.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: February 18, 2020
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: In Su Jang, Soon Chul Jung, Yoon Seok Choi, Jin Seo Kim
  • Patent number: 10551305
    Abstract: The invention relates to a method for determining the origin of a mixture of constituents by spectral analysis. The invention especially relates to a method for determining the concentration and origin of raw gases and/or crude oils in a mixing zone following mixing by the transport of said raw gases and/or crude oils that come from at least two different sources of extraction, said method comprising a specific spectral analysis.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: February 4, 2020
    Assignee: TOPNIR SYSTEMS SAS
    Inventors: Didier Lambert, Claude Saint Martin, Miguel Sanchez, Bernard Ribero
  • Patent number: 10502862
    Abstract: Methods and systems for locating a chemical source include measuring chemical concentration with sensors at a plurality of different positions. Measurements from pairs of positions are cross-correlated to determine an average velocity vector for a group of positions. A convergence region is determined based on a plurality of average velocity vectors to determine a chemical source location.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: December 10, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventor: Bruce G. Elmegreen
  • Patent number: 10448873
    Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: October 22, 2019
    Assignee: DexCom, Inc.
    Inventors: Sebastian Böhm, Daiting Rong, Peter C. Simpson
  • Patent number: 10422781
    Abstract: A dive computer with a free dive mode and/or wireless data transmission capabilities. In one embodiment the invention relates to a diving apparatus including a dive computer having a free dive mode, where the dive computer is configured to calculate a nitrogen loading in the free dive mode using a default value which is the fraction of oxygen in air, and where the free dive mode is used when a diver makes a dive without a self-contained underwater breathing apparatus. Another embodiment includes a method of operating a dive computer including recording two or more first identifiers, receiving pressure information from two or more pressure transmitters, the pressure information comprising second identifiers and pressure measurements, determining whether the pressure information contains one of the two or more first identifiers, and displaying a message indicative of the pressure information that contains one of the two or more first identifiers.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: September 24, 2019
    Assignee: Pelagic Pressure Systems Corp.
    Inventors: Robert R. Hollis, Michael S. Hollis, Jack Calvin Holman
  • Patent number: 10393883
    Abstract: The subject matter disclosed herein relates to determining a background location of a mobile device using one or more signal metrics.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: August 27, 2019
    Assignee: QUALCOMM Incorporated
    Inventors: Marc Anthony Ische, Ahmad Hatami, Ardalan Heshmati, Zoltan F. Biacs, Douglas Neal Rowitch, Dominic Gerard Farmer, Srigouri Kamarsu, Jie Wu
  • Patent number: 10386346
    Abstract: A data processing system for a chromatograph has an impurity detector including a differential chromatogram creator and a determining section. The differential chromatogram creator calculates a wavelength differential coefficient by differentiating an absorbance spectrum with respect to the wavelength at each point in time of the measurement and creates a differential chromatogram which shows a temporal change in the wavelength differential coefficient. Based on a shape of the thus created differential chromatogram, the determining section determines whether or not a peak of a target component contains an impurity. By this method, whether or not the peak of the target component contains an impurity can be determined with high accuracy, without requiring complex calculations.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: August 20, 2019
    Assignee: SHIMADZU CORPORATION
    Inventors: Yasuhiro Mito, Etsuho Kamata, Hiroshi Miura, Kenichi Mishima, Toshinobu Yanagisawa
  • Patent number: 10379234
    Abstract: A gamma-ray analysis system is described for analyzing gamma-ray emitting radionuclides. The gamma-ray analysis system includes an analytical apparatus having a gamma-ray detector in operative communication with a modular and scalable shield assembly that encases a sample container having a sample to be tested. The detector communicates data to an electronic interface device that converts the data from an analog format to a digital format before a controller transmits the data to a central laboratory for further data processing, analysis and conclusion by qualified laboratory analysts. The controller runs an application software package on a graphic user interface that allows simple steps for conducting testing and data acquisition by the end user, while permitting real time data transmission between the field site and the central location. Functions were implemented for ensuring laboratory quality results while removing knowledge and experience requirements of an end user.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: August 13, 2019
    Assignees: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services, Mirion Technologies, Inc., Mirion Technologies (Canberra UK) Limited
    Inventors: Cong Wei, Kelly M. Garnick, Thomas A. Scott, Elon M. Malkin, Jennifer T. Szymanski, Steve Laskos, James Cocks, Jeffrey Raimondi, Richard Mowry, Hiram Gonzalez, Ronald White, Wilhelm Mueller, Robert Fournier
  • Patent number: 10319574
    Abstract: Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: June 11, 2019
    Assignee: Highland Innovations Inc.
    Inventors: Eung Joon Jo, Yohahn Jo
  • Patent number: 10203319
    Abstract: The invention relates to a process for determining the degree of branching of modified polymers wherein the polymers are modified in the sense that their degree of branching after polymerization was increased once more, wherein the modified polymers are treated with a polar transformation mixture comprising a compound of general formula (I) R1—S—S—R1?? (I) wherein the Mooney viscosity (ML 1+4 at 100° C.) of the polymers is determined before and after the treatment with the polar transformation mixture and the degree of branching is determined.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: February 12, 2019
    Assignee: ARLANXEO DEUTSCHLAND GMBH
    Inventors: Heike Kloppenburg, Alicia Le-Sattler
  • Patent number: 10203277
    Abstract: There is provided a technique for automatically determining or predicting a line range specific to a sample that appears in a reaction curve in an automated analyzer for mixing a specimen and a reagent and measuring a change in a mixture of the specimen and the reagent with time. This invention approximates reaction curve data by a function and automatically determines a curve part at an early stage or a second stage of a reaction. The invention determines a line range not including a curve part for each sample and calculates a laboratory test value using absorbance data within the determined line range. This invention also automatically determines a start time of line at the early stage of the reaction on the basis of absorbance data obtained up to a point halfway through the reaction curve, predicts a line range on the basis of the end time of line and a planned end time of line, and calculates a predictive value on the basis of a result of the prediction.
    Type: Grant
    Filed: April 5, 2011
    Date of Patent: February 12, 2019
    Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Chihiro Manri, Satoshi Mitsuyama, Tomonori Mimura, Kumiko Kamihara
  • Patent number: 10190899
    Abstract: A thermal flow sensor with improved measurement accuracy is provided. The thermal flow sensor includes: an air flow rate detection element with a diaphragm having a thin-film portion in a semiconductor substrate; at least one heat generating resistor on the diaphragm; at least one temperature measuring resistor that detects temperature on each of an upstream side and a downstream side of the heat generating resistor; and a correction circuit portion that processes an output signal of the air flow rate detection element on the basis of temperature difference information of at least the two temperature measuring resistors on the upstream side and the downstream side, wherein a waveform of the output signal processed by the correction circuit portion is a waveform obtained by cutting a part of a mountain part or a valley part constituting a peak value by outputting of an arbitrary predetermined value when the peak value of the waveform exceeds the arbitrary predetermined value.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: January 29, 2019
    Assignee: Hitachi Automotive Systems, Ltd.
    Inventors: Ryosuke Doi, Shinobu Tashiro, Kazunori Suzuki, Masahiro Matsumoto
  • Patent number: 10134008
    Abstract: Embodiments of the present invention provide systems and methods for evaluating specification data of two or more components. In one embodiment, informational data, including specifications, provides details on these two or more components. The system then derives a set of interactions within these two or more components. From the informational data, in conjunction with interactions within the two or more components, it is determined whether one or more incompatibility issues exist. In instances where one or more incompatibility issues exist, the issue is highlighted and given a description.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: November 20, 2018
    Assignee: International Business Machines Corporation
    Inventor: Eric V. Kline
  • Patent number: 10060942
    Abstract: Systems and methods for measuring turbulent gas flux using high-speed vertical wind speed measurements (e.g., on the order of 5-10 Hz or more frequently) and low-speed gas content measurements (e.g., on the order of 5 Hz or less frequently), without the need for the sophisticated and expensive high-speed hardware to separate gas samples (e.g., into accumulation bags) according to updrafts and downdrafts. A time series of high-speed vertical wind speed data is used as a guide to distinguish between updrafts and downdrafts. When vertical wind speed is upward (updraft), the low-speed gas content is recorded into a data structure in one location, or marked with one flag. When vertical wind speed is downward (downdraft), the low-speed gas content is recorded into a different location, or marked with a different flag. Eddy Accumulation or Relaxed Eddy Accumulation computations can be performed using the stored gas content data to determine gas flux.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: August 28, 2018
    Assignee: Li-Cor, Inc.
    Inventors: George G. Burba, Dayle McDermitt, Xiaomao Lin, Liukang Xu, Dave Johnson
  • Patent number: 10001462
    Abstract: A method and system for detecting pesticide residue in agricultural products. The system includes a chromatographic and mass-spectrometric system and a computer. The system inspects first and second sample solutions prepared from two identical extracts of an agricultural product. The first sample solution includes no additives while the second sample is added with a pesticide standard which is intended to be detected by the system for comparison. The computer compares the mass chromatograms of the first and second sample solutions, and calculate an increased integral area by which the peak of the second sample solution in the second mass chromatogram exceeds the peak of the first sample solution in the first mass chromatogram at the same retention time. As such, the concentration of pesticide residue in the sample can be determined by a ratio between the increased integral area and the concentration of the pesticide standard.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: June 19, 2018
    Assignee: AGRICULTURAL CHEMICALS AND TOXIC SUBSTANCES RESEARCH INSTITUTE, COUNCIL OF AGRICULTURE, EXECUTIVE YUAN
    Inventors: Shao-Kai Lin, Wei-Chen Chuang