Using Radiant Energy Patents (Class 702/28)
  • Patent number: 10546243
    Abstract: This disclosure relates to a method for estimating a particle size distribution (PSD) and a morphology for a set of particles. A computer system receives a plurality of chord length distributions (CLDs) of different types for a set of particles. The computer system then estimates a morphology for the set of particles based on the plurality of received CLDs. The computer system also identifies a plurality of descriptors of the plurality of CLDs for the set of particles based on the plurality of received CLDs. The computer system then estimates metrics for the PSD for the set of particles based on the plurality of identified CLD descriptors. Based on the estimated PSD metrics for the set of particles, the computer system generates an estimate of the PSD for the set of particles. Finally, the computer system outputs the estimated morphology and the estimated PSD for the set of particles.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: January 28, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventor: Roberto Irizarry
  • Patent number: 10480718
    Abstract: Automated methods and systems for diverting transmix from a petroleum pipeline are provided to reduce the overall production of transmix on the pipeline, based on pre-defined programmed cut-points associated with the various subtypes of hydrocarbon carried on the pipeline.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: November 19, 2019
    Assignee: Texon LP
    Inventors: John Colin Robbins, Larry D. Mattingly, Gary S. Wawak
  • Patent number: 10444164
    Abstract: Provided is a method for acquiring information relating to a composition of a detected object from results of a measurement, using radiation, this method including: a step for acquiring by a computer a result of measuring the detected object using radiation; a step for estimating by a computer a chemical composition ratio of the detected object, using an equation that contains a value derived from the measurement result as a constant and contains a value derived from the chemical composition ratio of the detected object as a variable, and then solving the equation; and a step for outputting the estimated chemical composition ratio or a physical property value acquired based on the estimated chemical composition ratio as information relating to the composition of the detected object.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: October 15, 2019
    Assignee: Canon Kabushiki Kaisha
    Inventor: Taihei Mukaide
  • Patent number: 10430945
    Abstract: The present disclosure involves a computer-implemented unmixing algorithm that employs a least-square method involving image patches, and a computer-implemented unmixing or color deconvolution method that incorporates spatial smoothness and structure continuity constraints, for example, into a neighborhood graph regularizer, such as using a graph to enforce the pixel value similarities for those pixels in the same neighborhood.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: October 1, 2019
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Ting Chen, Srinivas Chukka
  • Patent number: 10395170
    Abstract: A method for determining a probability that ingredient materials found at a scene will be used for producing a target material, the method comprising using at least one hardware processor for: receiving input related to at least one ingredient material found at a scene; determining an ingredient material score from the input, the ingredient material score indicating a probability that the at least one ingredient material is found at the scene; and determining a target material score associated with a target material, the score indicative of a probability that the at least one ingredient material is used for producing the target material, wherein the target material score relates to a ratio between a sum of the ingredient material score of materials required for producing the target material and detected at the scene, and a number of ingredient materials required for producing the target material.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: August 27, 2019
    Assignee: CSA Technologies Ltd.
    Inventors: Avi Icar, Bogdan Belgorodsky
  • Patent number: 10352324
    Abstract: The invention relates to a method for determining the delivery rate of a pump. In this context, a value of the delivery level and a value of the power of the pump are determined. A probability density function is calculated for the delivery level and the power. A first probability density function of the delivery rate is calculated on the basis of a delivery level-delivery rate relationship and the probability density function of the delivery level. A second probability density function of the delivery rate is determined on the basis of a power-delivery rate relationship and the probability density function of the power. A combined probability density function of the delivery rate is determined on the basis of the first and second probability density functions. The delivery rate is determined on the basis of the combined probability density function.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: July 16, 2019
    Assignee: KSB Aktiengesellschaft
    Inventors: Stefan Laue, Jochen Schaab
  • Patent number: 10261058
    Abstract: One embodiment of the invention is directed to a method of analyzing liquid chromatography data. The method comprises collecting, by a data processing system, first volume fractions data from a first liquid chromatography column for a first absorbance wavelength of light ?1 from a first run of a liquid chromatography process on a mixture, wherein the first liquid chromatography column screens for a first characteristic of the mixture.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: April 16, 2019
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Jeff Habel
  • Patent number: 10151687
    Abstract: The present disclosure provides systems, apparatuses, and methods for fluid analysis. Embodiments include a removable and replaceable sampling system and an analytical system connected to the sampling system. A fluid may be routed through the sampling system and real-time data may be collected from the fluid via the sampling system. The sampling system may process and transmit the real-time data to the analytical system. The analytical system may include a command and control system that may receive and store the real-time data in a database and compare the real-time data to existing data for the fluid in the database to identify conditions in the fluid.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: December 11, 2018
    Inventors: Dustin Young, Mark Chmielewski, Chris Morton
  • Patent number: 10101675
    Abstract: Disclosed is a metrology apparatus and method for measuring a structure formed on a substrate by a lithographic process. The metrology apparatus comprises an illumination system operable to provide measurement radiation comprising a plurality of wavelengths; and a hyperspectral imager operable to obtain a hyperspectral representation of a measurement scene comprising the structure, or a part thereof, from scattered measurement radiation subsequent to the measurement radiation being scattered by the structure.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: October 16, 2018
    Assignee: ASML Netherlands B.V.
    Inventors: Alessandro Polo, Simon Gijsbert Josephus Mathijssen
  • Patent number: 10088404
    Abstract: A method for determining a shape of particles in a distribution with reduced measuring and analyzing complexity includes detecting the number of particles, measuring and storing a particle chord length for each particle as a measurement for particle size and measuring at least first and second distributions of the particle size from the particle chord length measured for each particle. The first distribution is based on a first quantity type, the second distribution is based on a second quantity type and the quantity types correspond to different powers of the particle size. A first distribution parameter, corresponding to a cumulative or density distribution, of the first distribution is set into a distribution parameter ratio with a second distribution parameter, corresponding to a cumulative or density distribution, of the second distribution. An aspect ratio is determined from the distribution parameter ratio as a value characterizing the shape of the particles.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: October 2, 2018
    Assignee: Parsum Gesellschaft fuer Partikel-, Stroemungs- und Umweltmesstechnik mbH
    Inventors: Stefan Dietrich, Dieter Petrak, Michael Koehler, Guenter Eckardt
  • Patent number: 10068305
    Abstract: Implementations include methods for monitoring and reporting on actual hazardous conditions at a facility including actions of receiving data associated with a site, the site being susceptible to potentially hazardous conditions, processing the data, one or more models, and one or more prediction rules, determining that a hazardous condition is predicted to occur at the site, providing output data reflecting the hazardous condition, processing the output data to provide indicator data for providing a graphical representation of the site, the graphical representation providing a graphical depiction of the hazardous condition, and providing the indicator data to one or more user devices, the indicator data being processed by each of the one or more user devices to display the graphical representation.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: September 4, 2018
    Assignee: WellAware Holdings, Inc.
    Inventors: David Allen Sisk, Roel Almendarez, Cody James Lee
  • Patent number: 9666421
    Abstract: A mass spectrometry data display device in which the mass axis (m/z axis) is made into a ring shape and the intensity axis is the radial direction thereof, and peak information (in the drawing, the compound name and structural formula candidates) are arranged in a ring shape in correspondence with the peaks along the outer circumference of the mass spectrum and displayed together therewith on a screen.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: May 30, 2017
    Inventor: Yohei Yamada
  • Patent number: 9627175
    Abstract: An electron microscope includes an acquisition section that acquires an electron microscope image of a specimen that includes a plurality of identical patterns, and a spectrum at each pixel of the electron microscope image, and an elemental map generation section that adds up the spectrum at each pixel of each of a plurality of areas that are included in the electron microscope image and have an identical size to generate an elemental mapping image of the specimen.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: April 18, 2017
    Assignee: JEOL Ltd.
    Inventors: Masaki Morita, Akira Yasuhara
  • Patent number: 9557273
    Abstract: Disclosed herein is a quantitative analyzing method of a copper indium gallium selenide (CIGS) film, the method including: obtaining spectra by irradiating a laser on the plurality of CIGS films having different component compositions, selecting a first spectral line and a second spectral line among the spectra of target elements to be analyzed and obtaining a correlation plot between a measured intensity of the first spectral line and a measured intensity of the second spectral line, correcting the measured intensity of the first spectral line and the measured intensity of the second spectral line using results obtained by curve fitting the correlation plot, obtaining a linear calibration curve using the corrected intensity of the first spectral line and the corrected intensity of the second spectral line; and comparing the linear calibration curve with LIBS analysis of a target sample to be analyzed.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: January 31, 2017
    Inventors: Sungho Jeong, Jeong Hwan In, Chan Kyu Kim, Seokhee Lee, Hakjae Lee
  • Patent number: 9557394
    Abstract: Methods for determining the identity of a substance are provided. A classification parameter set is defined to allow identification of substances that previously could not be identified or to allow identification of substances with a higher degree of confidence. The classification parameter set may include at least one of relative nuclear susceptibility (RNS) or an x-ray linear attenuation coefficient (LAC). RNS represents the density of hydrogen nuclei present in a substance relative to the density of hydrogen nuclei present in water. The extended classification parameter set may include T1, T2, and/or T1? as well as at least one additional classification parameter comprising one of RNS or LAC. Values obtained for additional classification parameters as well as values obtained for T1, T2, and T1? can be compared to known classification parameter values to determine whether a particular substance is a known material.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: January 31, 2017
    Assignee: U.S. Department of Energy
    Inventors: Michelle A. Espy, Andrei N. Matlashov, Larry J. Schultz, Petr L. Volegov, Algis Urbaitis, Henrik Sandin, Jacob Yoder, Stephen Surko
  • Patent number: 9535017
    Abstract: The invention relates to a device for identifying a material of an object having: a source of X photons and a spectrometric detector, the source irradiating the object with an incident beam and the detector measuring a magnitude of a backscattered beam from the incident beam after diffusion in a volume of the material and an energy of the X photons of the backscattered beam, the incident and backscattered beams forming an angle of diffusion (?); a configuration for adjusting the position between the source, the detector and the object in order for the volume to be at different depths with a constant angle, a means for processing the two magnitudes in two positions and the energy in on position and for calculating an attenuation factor (?materiau (E0, E1, ?)), a configuration for estimating the density (p) of the material.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: January 3, 2017
    Assignee: Commissariat a L'Energie Atomique et aux Energies Alternatives
    Inventors: Caroline Paulus, Joachim Tabary
  • Patent number: 9453828
    Abstract: Method and system is described for hydrocarbon exploration and development. The method and system include one or more remote devices, such as buoys, which are utilized to identify and collect samples of target materials. The buoys include measurement components, sampling components and storage components to manage the obtained samples.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: September 27, 2016
    Assignee: ExxonMobil Upstream Research Company
    Inventors: Kevin T. Corbett, William E. Bond, Robert J. Pottorf, Aaron B. Regberg, A. Lucie N'Guessan, Scott C. Hornbostel, William P. Meurer, Louise Levien, Glenn B. Hieshima, Timothy J. Nedwed
  • Patent number: 9287097
    Abstract: The simulation method is for predicting a damage amount due to ultraviolet rays in manufacturing a semiconductor device.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: March 15, 2016
    Inventors: Nobuyuki Kuboi, Tetsuya Tatsumi, Masanaga Fukasawa
  • Patent number: 9275841
    Abstract: A time of flight (TOF) spectrometer and a method for operating the same is disclosed. The spectrometer includes an event extractor, a streaming processor, and a FIFO buffer. The event extractor generates a ion event record corresponding to each detected ion, the ion event record including an intensity of a plurality of aliases for that detected ion. The streaming processor includes a memory array that stores a TOF spectrum and a probability processor that provides a probability for each alias in each received ion event record and updates the TOF spectrum based on the probabilities. A FIFO buffer receives each of the ion event records after the TOF spectrum has been updated and outputs the oldest ion event record to the streaming processor when a new ion event record is processed by the streaming processor.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: March 1, 2016
    Assignee: Agilent Technologies, Inc.
    Inventor: George Stennis Moore
  • Patent number: 9091653
    Abstract: A method for wavelength-selective and high spatial resolving fluorescence microscopy. In a specimen fluorescence emitters are repeatedly excited and specimen frames are produced with a microscope. The fluorescence emitters are excited to emit fluorescence radiation such that at least a sub-set is isolated in each frame and the positions of the isolated fluorescence emitters are localized with a localization precision exceeding the optical resolution and a high-resolution complete image is produced.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: July 28, 2015
    Assignee: Carl Zeiss Microscopy GmbH
    Inventors: Thomas Kalkbrenner, Ralf Wolleschensky
  • Patent number: 9042517
    Abstract: To provide an X-ray imaging apparatus capable of easily adjusting the sensitivity or capable of easily extracting the amount of refraction of X-rays. An X-ray imaging apparatus irradiating an object to be measured with an X-ray beam from an X-ray source that generates X-rays of a first energy and X-rays of a second energy different from the first energy to measure an image of the object to be measured includes an attenuator and a detector. The attenuator attenuates the X-ray beam transmitted through the object to be measured and is configured so as to vary the amount of attenuation of the X-rays depending on a position on which the X-ray beam is incident. The detector detects the X-ray beam transmitted through the attenuator and is configured so as to detect the X-rays of the first energy and the second energy.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: May 26, 2015
    Assignee: Canon Kabushiki Kaisha
    Inventors: Kazunori Fukuda, Kazuhiro Takada, Taihei Mukaide, Masatoshi Watanabe
  • Publication number: 20150134269
    Abstract: A method that includes obtaining, using a processor, reflectance data from a target coating and calculating, using the processor, virtual color response data using one of at least one Kepler's laws of planetary motion equation and at least one derivation of at least one Kepler's laws of planetary motion equation. The method also includes generating, using the processor, a coating formulation that is the same or substantially similar in appearance to the target coating.
    Type: Application
    Filed: November 7, 2014
    Publication date: May 14, 2015
    Inventor: ALISON M. NORRIS
  • Patent number: 9031189
    Abstract: An X-ray imaging apparatus acquiring a differential phase contrast image of a test object without using a light-shielding mask for X-ray. The apparatus includes an X-ray source, a splitting element configured to spatially divide an X-ray emitted from an X-ray source and a scintillator configured to emit light when a divided X-ray beam divided at the splitting element is incident on the scintillator. The apparatus also includes a light-transmission limiting unit configured to limit transmitting amount of the light emitted from the scintillator and a plurality of light detectors each configured to detect the amount of light that has transmitted through the light-transmission limiting unit. The light-transmission limiting unit is configured such that a light intensity detected at each of the light detectors changes in response to a change in an incident position of the X-ray beam.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: May 12, 2015
    Assignee: Canon Kabushiki Kaisha
    Inventors: Taihei Mukaide, Takashi Noma, Kazunori Fukuda, Masatoshi Watanabe, Kazuhiro Takada
  • Publication number: 20150120213
    Abstract: A system for identifying or distinguishing materials, comprising at least one local apparatus and a central station. Each local apparatus comprises at least one measuring device for recording at least one actual signature for materials each and at least one local computer communicatively connected to the at least one measuring device, the at least one local computer having a local database for storing and/or processing the actual signature. The at least one central station comprises a server having a central database for storing and/or processing the actual signatures of the local apparatus. Furthermore, the system comprises a network, which communicatively connects the local computers of the local units via the server of the center. The invention further relates to a corresponding method for operating a system, to an analysis method for identifying or distinguishing the materials, and to a measuring device for recording material properties of the materials.
    Type: Application
    Filed: January 9, 2015
    Publication date: April 30, 2015
    Inventor: Stefan Nettesheim
  • Patent number: 9020764
    Abstract: The concept underlying the invention is the development of a generic method for the detection and identification of gases in airplane interior spaces and an associated device, which is small and manageable, has a simple design, and allows the immediate and simultaneous detection and identification of the gases to be examined. This is achieved in that the supply air of the airplane interior space (20) is fed to a measuring device (1) and the measurement results of the measuring device (1) are analyzed by means of mathematical methods. Such methods and the associated devices for the detection and identification of gases in airplane interior spaces are used in order to spot and verify gases, particularly odors and explosive gases and/or gases harmful to people's health.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: April 28, 2015
    Assignee: Airsense Analytics GmbH
    Inventors: Andreas Walte, Wolf Münchmeyer, Mario Schmidt
  • Publication number: 20150100249
    Abstract: A method of analysis of a heterogeneous product, for example heparin or heparin derivatives, to define whether said heterogeneous product is consistent with a library of verified heterogeneous samples (Library 1) by analysing the variation, natural or alien. The acceptable variation of the heterogeneous product is determined by comparing Library 1 with a second set of verified spectra (Library 2), by use of comparative two-dimensional correlation spectroscopic filtering (comparative 2D-COS-f). The method comprises obtaining a one-dimensional complex spectrum, for example 1H-NMR spectra, of a heterogeneous product and testing if it has features that are greater than features found testing a spectrum from Library 2 against Library 1. In a second embodiment comparative 2D-COS-f with iterative random sampling (2D-COS-firs) is applied, which provides a more accurate and stable extraction of aliens/unnatural features.
    Type: Application
    Filed: May 10, 2013
    Publication date: April 9, 2015
    Applicants: Istituto Di Ricerche Chimiche E Biochimiche "G. Ronzoni", Anglo-Italian Chemometrics LTD.
    Inventors: Giangiacomo Torri, Marco Guerrini, Timothy Robert Rudd
  • Patent number: 8972205
    Abstract: The present invention provides, inter alia, methods of characterizing a small molecule organic material, e.g., a drug or a drug product. This method includes subjecting the solid small molecule organic material to x-ray total scattering analysis at a short wavelength, collecting data generated thereby, and mathematically transforming the data to provide a refined set of data.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: March 3, 2015
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Simon Billinge, Kenneth Shankland, Norman Shankland, Alastair Florence
  • Patent number: 8952324
    Abstract: The mass analyzing apparatus of the present invention can achieve the speed-up and simplification of the formation of a calibration curve for quantifying an analysis object in a mass analyzing apparatus.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: February 10, 2015
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Midori Sasaki, Terumi Tamura, Shinya Ito, Makoto Nogami
  • Patent number: 8941056
    Abstract: A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitized. Arrival time and intensity pairs are calculated for both digitized signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: January 27, 2015
    Assignee: Micromass UK Limited
    Inventors: Martin Raymond Green, Steven Derek Pringle, Jason Lee Wildgoose
  • Patent number: 8942927
    Abstract: A system and method for measuring elemental concentrations of a material from a sample containing several elements by LIES analysis is provided. The material is heated to generate plasma and its chemical composition is determined from spectral analysis of its radiation. The spectral lines of interest are identified among those emitted by constituents of each element composing sample, and their intensities are measured. The chemical composition of the plasma is calculated. The absorption coefficient according to wavelength is calculated for the spectral zones of the lines of interest. The spectral radiance of the plasma is calculated for the same spectral zones and then a comparison of the intensity and shape of the spectrum thus calculated with those of the spectrum measured is performed. These calculations and this comparison are repeated iteratively in order to adjust the temperature, electron density, relative values of the elemental concentrations and width of the plasma.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: January 27, 2015
    Assignee: Centre National de la Recherche Scientifique —CNRS—
    Inventor: Jörg Hermann
  • Publication number: 20140379279
    Abstract: A method of characterising a sample from spectrometric data using calculation of spectral distance values is disclosed, for use in the field of mass spectrometry. Molecular formula assignment of peaks in mass spectral data is difficult and time-consuming, and the invention provides a computer implemented method of finding a most likely elemental composition of a measured spectral peak of interest. The method analyses isotopic peaks in a portion of the spectrum, using both their mass positions and intensities, to determine a spectral distance between those peaks and isotopic peaks of a candidate composition, finding peaks that match (140). A pattern spectral distance is determined (150) to provide a measure of the correspondence between a set of those peaks in the measured spectrum and peaks of each of a number of candidate compositions. The spectral fit is used to determine a most likely candidate composition.
    Type: Application
    Filed: September 8, 2014
    Publication date: December 25, 2014
    Inventor: Hans PFAFF
  • Publication number: 20140379278
    Abstract: Apparatus and methods of spectral searching that employ wavelet coefficients as the basis for the searching. The disclosed apparatus and methods employ a wavelet lifting scheme to transform spectroscopic data corresponding to an unknown pure material/mixture to a vector of wavelet coefficients, compare the wavelet coefficient vector for the unknown pure material/mixture with a library of wavelet coefficient vectors for known pure materials/mixtures, and identify the closest match to the unknown pure material/mixture based on the comparison of wavelet coefficient vectors.
    Type: Application
    Filed: June 20, 2013
    Publication date: December 25, 2014
    Inventor: Scott B. Tilden
  • Patent number: 8918290
    Abstract: A method and system to identify an unknown metal alloy based on its chemical composition is provided in the present application. The chemical elements contained in the alloy are separated into key elements and trap elements. Then a similarity factor between a relative amount of each key element and a threshold value of said key elements is determined and a correlation factor is formed based on the similarity factors.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: December 23, 2014
    Assignee: Key To Metals AG
    Inventor: Viktor Pocajt
  • Publication number: 20140358451
    Abstract: Methods and systems for detecting and quantifying signal peaks from ESI-TOF-MS data may include creating a signal model and a noise model for mass spectrometry (MS) data. The method may also include detecting a signal peak based, at least in part, on the signal model and the noise model for the MS data. The method may further include determining an amplitude of the detected signal peak based, at least in part, on the signal model and the noise model for the MS data.
    Type: Application
    Filed: June 4, 2014
    Publication date: December 4, 2014
    Inventors: Sai Buddi, Thomas Taylor, Randy Nelson, Chad Borges, Douglas Cochran
  • Patent number: 8901494
    Abstract: A sample analyzer is offered which creates a ternary scatter diagram representing a concentration ratio distribution of three elements out of several elements to be analyzed. This three-dimensional graph is created by adding an axis to the ternary scatter diagram and representing concentration information about the two additional elements on the added axis. The sample analyzer performs elemental analysis of a sample by scanning a primary beam over the sample and detecting a signal emanating from the sample. The added axis intersects the plane of the ternary scatter diagram.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: December 2, 2014
    Assignee: JEOL Ltd.
    Inventor: Shingo Kinoshita
  • Publication number: 20140350867
    Abstract: The present invention is directed to a system for producing a target composition having one or more target property values. The system provides real time measurements of property values of the target composition being produced. The system can further provide real time image of the target composition for quality control and adjustment on one or more property values, such as color property values. The system can be used for producing the target composition, such as coating compositions, with improved quality control and increased productivity. The system can be used for OEM or refinish coating manufacturing or small volume paint mixing or adjustment operations.
    Type: Application
    Filed: November 20, 2012
    Publication date: November 27, 2014
    Inventors: Jeff B. Alspach, Gary T. Weaks, Robert K. Vandette, Brian James Ladd, Allan Blase Joseph Rodrigues
  • Publication number: 20140343873
    Abstract: This disclosure provides for new methods for quantification of metabolite concentrations in metabolomics studies, which addresses the difficulties in quantification through 1D peak integrals due to significant peak overlaps in metabolomics samples. For samples from uniformly 13C-labeled organisms the 2D NMR 13C-13C constant-time (CT) TOCSY experiment provides high-resolution information about individual metabolites that allows their identification via database searching or, in the case of novel compounds, through the reconstruction of their backbone-carbon topology. This disclosure further demonstrates using CT-TOCSY spectra for quantification purposes.
    Type: Application
    Filed: May 15, 2014
    Publication date: November 20, 2014
    Inventors: Rafael Brüschweiler, Kerem Bingol
  • Patent number: 8890060
    Abstract: A method of processing an image charge/current signal representative of trapped ions undergoing oscillatory motion. The method includes applying a validity test to each of a plurality of peaks in the image charge/current signal in the frequency domain, wherein applying the validity test to a peak in the image charge/current signal in the frequency domain includes determining whether a phase angle associated with the peak meets a predetermined condition. The method also includes forming a new image charge/current signal that: includes data representative of one or more peaks that have passed the validity test; and excludes data representative of one or more peaks that have failed the validity test. The method may be performed by a mass spectrometry apparatus.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 18, 2014
    Assignee: Shimadzu Corporation
    Inventors: Li Ding, Ranjan Badheka
  • Patent number: 8880356
    Abstract: A method and system for spectrum data analysis. The method comprises the steps of collecting a spectrum of an unknown material; providing a set of data templates; calculating weighting factors for the element data templates to minimize error in approximating the spectrum; removing one or more of the templates having negative weights in approximating the spectrum; and re-calculating an approximation of the spectrum with said one or more templates removed. Embodiments of the invention are suitable for analyzing noisy spectra having relatively few data points.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: November 4, 2014
    Assignee: Fei Company
    Inventors: Daniel Roy Corbett, Paul Gottlieb, Andrew Harley Menzies, Michael James Owen
  • Publication number: 20140324362
    Abstract: Techniques are described for resolving and identifying peaks of signal intensity in mass chromatograms so that the peaks may be associated with components (e.g., chemical and/or ionic species) representative of an analysis sample to identify the components. The techniques facilitate correction of shift errors in the peaks of signal intensity of the mass chromatograms.
    Type: Application
    Filed: August 17, 2012
    Publication date: October 30, 2014
    Inventors: Greger Andersson, Kevin Judge
  • Publication number: 20140297202
    Abstract: One embodiment provides a method of determining an unknown degree of crystallinity, the method comprising: constructing a master curve plot comprising a plurality of reference curves, each reference curve representing a relationship between electrical resistivity and temperature for one of a plurality of reference alloy samples having a chemical composition and various pre-determined degrees of crystallinity; for an alloy specimen having the chemical composition and the unknown degree of crystallinity, obtaining a curve representing the electrical resistivity and temperature thereof; and determining the unknown degree of crystallinity by comparing the curve to the master curve plot.
    Type: Application
    Filed: August 5, 2011
    Publication date: October 2, 2014
    Applicant: Apple Inc.
    Inventors: Stephen P. Zadesky, Christopher D. Prest, Theodore A. Waniuk
  • Publication number: 20140297201
    Abstract: The invention relates to a method for analysing mass spectral data obtained from a sample in GC×GC (2-dimensional) mass spectrometry, comprising: (a) comparing mass spectral data of an analyte with mass spectral data of candidate compounds of known structure in a data library; (b) identifying a plurality of candidate compounds from the library based on similarities of mass spectral data; (c) predicting, for each candidate compound, a value of at least one analytical property using a quantitative model based on a plurality of molecular descriptors; and (d) calculating a match score for each candidate compound based on the value predicted in step (c) and a measured value of the analytical property for the analyte.
    Type: Application
    Filed: April 30, 2012
    Publication date: October 2, 2014
    Inventors: Arno Knorr, Aurelien Monge, Markus Stueber, Pavel Pospisil
  • Patent number: 8843323
    Abstract: Complex gun code computations can be made to converge more quickly based on a selection of one or more relaxation parameters. An eigenvalue analysis is applied to error residuals to identify two error eigenvalues that are associated with respective error residuals. Relaxation values can be selected based on these eigenvalues so that error residuals associated with each can be alternately reduced in successive iterations. In some examples, relaxation values that would be unstable if used alone can be used.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: September 23, 2014
    Assignee: Los Alamos National Security, LLC
    Inventor: Eric M. Nelson
  • Publication number: 20140278147
    Abstract: A crystalline phase identification method, a crystalline phase identification device, and a crystalline phase identification program which can conduct qualitative analysis with higher precision are provided.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Rigaku Corporation
    Inventors: Akito SASAKI, Akihiro HIMEDA
  • Patent number: 8829430
    Abstract: A method is provided for calibrating mass-to-charge ratio measurements obtained from a time-of-flight mass spectrometer used as a detector for a chromatographic system. The method can include introducing a calibrant material into the time-of-flight mass spectrometer after a sample is introduced to the chromatographic system, but before the analysis of the sample is complete, such that calibrant material and sample material are not present at the ion source of the mass spectrometer, contemporaneously. The method can include acquiring a multiplicity of mass spectra of the calibrant material during an analytical run, and in some embodiments, calculating a multiplicity of mass calibrations on the basis of mass spectra obtained from the calibrant material introduced during the analytical run.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: September 9, 2014
    Assignee: Zoex Corporation
    Inventor: Edward B. Ledford, Jr.
  • Patent number: 8828728
    Abstract: An aquatic environment monitoring system and method that includes correction for adverse conditions in the monitoring system involving the development of confidence levels for certain conditions in the monitoring system using stored information related to the aquatic environment and/or the monitoring system. Corrections to adverse conditions may be made by the environment monitoring system automatically by the monitoring system and manually via communications to a user of the system.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: September 9, 2014
    Assignee: Step Ahead Innovations, Inc.
    Inventor: James E. Clark
  • Publication number: 20140249766
    Abstract: In estimating a structural formula of an unknown substance produced through partial structural change of an original substance having a known structure caused by metabolism or the like, structural change is considered in two stages, the elimination of a partial structure and the addition of another partial structure. First, an additional partial structure is collected as known information in addition to an MSn spectrum of the unknown substance and a structural formula of the original substance. A structural formula at the time when a partial structure is eliminated from the original substance is estimated, and a structural formula of each of product ions is estimated. The structural formula of the unknown substance is determined by estimating a structure that can produce the candidates for structural formulas of the product ions by dissociation.
    Type: Application
    Filed: October 7, 2011
    Publication date: September 4, 2014
    Inventors: Hiroaki Kozawa, Shinichi Yamaguchi
  • Patent number: 8812250
    Abstract: Ion mobility spectrometry systems, devices, and associated methods of operation are disclosed herein. In one embodiment, a method for performing ion mobility spectrometry includes ionizing a sample in gas phase and applying an electric field to the ionized sample in the gas phase, thereby moving the ionized sample along a drift region. The applied electric field has a plurality of strength values with respect to time, and the individual strength values being generally constant during a corresponding period of time. The method further includes detecting an ion intensity and a drift time of the ionized sample moving through the drift region under the applied electric field with the plurality of strength values.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: August 19, 2014
    Assignee: Washington State University
    Inventors: Herbert H. Hill, Eric J. Davis
  • Publication number: 20140229010
    Abstract: The method and apparatus are used to determine class, grade and properties of fuel samples, regardless of ambient, instrument, or sample temperature, using mathematical correlations between fuel class, grade and properties and their spectra developed from a database of samples with measured properties and spectra. The ability to measure a fuel sample using the present method and apparatus is useful in identifying unknown fuel samples, determining suitability in equipment, and monitoring and controlling fuel processes, such as blending operations, distillation, and synthesis.
    Type: Application
    Filed: April 22, 2014
    Publication date: August 14, 2014
    Applicant: Real-Time Analysers, Inc.
    Inventors: Stuart Farquharson, Wayne W. Smith
  • Patent number: 8803079
    Abstract: An apparatus for elemental analysis of particles such as single cells or single beads by mass spectrometry is described. The apparatus includes means for particle introduction; means to vaporize, atomize and ionize elements associated with a particle; means to separate the ions according to their mass-to-charge ratio; means to detect the separated ions, means to digitize the output of the means to detect the ions; means to transfer and/or to process and/or record the data output of the means to digitize, having means to detect the presence of a particle in a mass spectrometer; and means to synchronize one of the means for ion detection, data digitization, transfer, processing and recording with the means to detect the presence of a particle. Methods and computer readable code implementing aspects of the apparatus, and for reducing the rates of data generation, digitization, transfer, processing and recording are also described.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: August 12, 2014
    Assignee: Fluidigm Canada Inc.
    Inventors: Alexei Antonov, Dmitry Roman Bandura