Chemical Property Analysis Patents (Class 702/30)
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Publication number: 20130304397Abstract: A method of measuring a capacitance (C) of a sensor having a working electrode that is coated by an insulating layer and a ligand forming an affinity surface. The method involves the steps of bringing the electrode into contact with an analyte, supplying a constant first current (I1), and a constant second current (I2) of opposite direction to the first current (I1), and a constant third current (I3) of same direction as the first current (I1) during determined time periods to the sensor. Further the method includes sampling the potential (V) built up across the sensor, and calculating the capacitance of the sensor from the inclination (B, D, F, H) of a potential curve received in response to the current supply. A method used for detection of an interaction between a ligand and an analyte is also disclosed.Type: ApplicationFiled: October 31, 2011Publication date: November 14, 2013Applicant: CAPSENZE HBInventors: Dag Erlandsson, Martin Hedstrom, Bo Mattiasson, Joakim Larsson
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Publication number: 20130297228Abstract: Disclosed is a method of measuring radioactive material of an ingot, in which an ingot having a volume produced by subjecting metal waste generated in nuclear fuel processing or production facilities to melting decontamination undergoes gamma spectroscopy using a NaI detector to measure gamma rays of U-235 (185.72 keV, 57.2%) among uranium isotopes, followed by performing detector calibration using a certified reference material and self-absorption correction depending on the density of a medium using MCNP computer code, and which enables rapid determination of whether the ingot subjected to melting decontamination may be self-disposed of or not.Type: ApplicationFiled: April 30, 2013Publication date: November 7, 2013Applicant: KEPCO NUCLEAR FUEL CO., LTD.Inventors: Suk Ju CHO, Young Bae LEE, Jeung Gun SEOL, Yong Jae KIM, Jae Bong RYU
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Publication number: 20130297229Abstract: Disclosed is a method of measuring radioactive material of an ingot, in which an ingot having a volume produced by subjecting metal waste generated in nuclear fuel processing or production facilities to melting decontamination undergoes gamma spectroscopy using a HPGe detector to measure gamma rays of U-235 (185.72 key, 57.2%) among uranium isotopes, followed by performing detector calibration using a certified reference material and self-absorption correction depending on the density of a medium using MCNP computer code, and which enables rapid determination of whether the ingot subjected to melting decontamination may be self-disposed of or not.Type: ApplicationFiled: April 30, 2013Publication date: November 7, 2013Applicant: KEPCO NUCLEAR FUEL CO., LTD.Inventor: KEPCO NUCLEAR FUEL CO., LTD.
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Patent number: 8577623Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochloritc, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.Type: GrantFiled: September 14, 2012Date of Patent: November 5, 2013Assignee: Hach CompanyInventor: Thomas D. Wolfe
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Publication number: 20130288379Abstract: A method of producing an alkylene oxide includes passing a reaction mixture comprising alkylene, oxygen and a gaseous chlorine-containing promoter species over a supported catalyst containing silver and a promoting amount of rhenium to undergo an epoxidation reaction at a first operating condition. The method further includes subsequently performing the epoxidation reaction at a preferred operating condition. The preferred operating condition is characterized by an efficiency of the epoxidation reaction toward the alkylene oxide where the efficiency is lower than that of a maximum efficiency achievable at an operating temperature corresponding to the preferred operating condition.Type: ApplicationFiled: June 27, 2013Publication date: October 31, 2013Inventors: Michael Habenschuss, Hwaili Soo, Paul V. Hinman, Albert C. Liu
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Patent number: 8571812Abstract: A method for determining the oxygen concentration of a sample made of a semiconductor material includes a heat treatment step of the sample to form thermal donors, the measurement of the resistivity in an area of the sample, the determination of the thermal donor concentration from a relation expressing the charge carrier mobility according to an ionized dopant impurity concentration, by adding to the dopant impurity concentration four times the thermal donor concentration, and from the measured resistivity value. The method finally includes determining the oxygen concentration from the thermal donor concentration.Type: GrantFiled: August 30, 2011Date of Patent: October 29, 2013Assignee: Commissariat a l'Energie Atomique et aux Energies AlternativesInventors: Jordi Veirman, Sebastien Dubois, Nicolas Enjalbert
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Patent number: 8569045Abstract: Provided are a water toxicity detecting apparatus and a method using sulfur particles.Type: GrantFiled: September 12, 2008Date of Patent: October 29, 2013Assignee: University-Industry Cooperation Foundation, Kangwon UniversityInventor: Sang Eun Oh
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Publication number: 20130270492Abstract: In a method of preparing a liquid solution by mixing ingredients according to a predetermined recipe, wherein at least one pair of species of the liquid solution is derived from a weak electrolyte and corresponds to an acid-base pair, the conductivity of the liquid solution is predicted by: (i) for each pair of species derived from a weak electrolyte, solving a respective equilibrium equation to calculate the actual molar concentration of each such species at equilibrium in the liquid solution, (ii) calculating for each ionic species of said plurality of species the molar conductivity by the formula: ?=?0?K×Sqrt(c) wherein ? is the molar conductivity, ?0 is the molar conductivity at infinite dilution, c is the concentration, and K is the Kohlrausch coefficient, and wherein K and ?0 are predetermined values for K and ?0 for each ionic species, (iii) calculating the conductivity x for each ionic species by the formula: ?=c×? and (iv) adding up the conductivities determined in step (iii) forType: ApplicationFiled: December 15, 2011Publication date: October 17, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventor: Enrique Carredano
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INTERMOLECULAR INTERACTION MEASUREMENT METHOD, MEASUREMENT SYSTEM FOR USE IN THE METHOD, AND PROGRAM
Publication number: 20130267034Abstract: A measuring method of an intermolecular interaction for optically measuring an intermolecular interaction between a plurality of substances on a thin film, the method comprising: detecting intensity at a first wavelength of reflected light or transmitted light before start of the intermolecular interaction with a detection unit which detects the reflected light from the thin film or the transmitted light transmitted through the thin film; detecting intensity at the first wavelength of the reflected light or the transmitted light after the start of the intermolecular interaction with the detection unit; and calculating a difference in intensity of the reflected light or the transmitted light at the first wavelength between before and after the start of the intermolecular interaction.Type: ApplicationFiled: December 6, 2011Publication date: October 10, 2013Inventors: Naoki Izumiya, Yuka Yoshihara -
Publication number: 20130261986Abstract: An object of the present invention is to provide a method for rapidly and accurately determining the lipophilicity of a wide variety of substances.Type: ApplicationFiled: December 26, 2011Publication date: October 3, 2013Applicant: ASTELLAS PHARMA INC.Inventors: Ryo Mizoguchi, Katsuhiko Gato
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Publication number: 20130238255Abstract: A system for managing a concrete delivery vehicle having a mixing drum 14 and hydraulic drive 16 for rotating the mixing drum, including a rotational sensor 20 configured to sense a rotational speed of the mixing drum, a hydraulic sensor 22 coupled to the hydraulic drive and configured to sense a hydraulic pressure required to turn the mixing drum, a temperature sensor for sensing temperature of the drum, and a communications port 26 configured to communicate a slump calculation to a status system 28 commonly used in the concrete industry, wherein the sensing of the rotational speed of the mixing drum is used to qualify a calculation of current slump based on the hydraulic pressure required to turn the mixing drum. Temperature readings are further used to qualify or evaluate a load. Also, water purge connections facilitate cold weather operation.Type: ApplicationFiled: April 30, 2013Publication date: September 12, 2013Applicant: VERIFI LLCInventors: Roy Cooley, John I. Compton, Michael Topputo, Steve Verdino, Jerold Brickler
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Patent number: 8521442Abstract: An exemplary method for measuring the electrical resistance and/or electrical conductivity of solutions, includes: exciting the electrodes with a rectangular shaped, alternating current of a certain frequency fH through a connecting cable; synchronously rectifying a voltage of the electrodes of the measuring cell in response to the alternating current, calculating a first average voltage, dividing the first average voltage by the current amplitude to obtain a first impedance RH; then exciting the electrodes with a rectangular shaped, alternating current of another frequency fL through the connecting cable; synchronously rectifying the voltage of the electrodes in response to the alternating current, calculating a second average voltage, and dividing the second average voltage by the current amplitude to obtain a second impedance RL.Type: GrantFiled: December 12, 2008Date of Patent: August 27, 2013Assignee: Mettler-Toledo AGInventor: Changlin Wang
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Publication number: 20130218481Abstract: There is provided a method for determining Total Acid Number (TAN) in a fluid fossil fuel, such as a crude oil, comprising: separating said fluid fossil fuel by liquid chromatography into a plurality of fractions, comprising at least one acidic fraction; determining boiling point distribution of said crude oil, of said acidic fraction, and of said polyacidic fraction by simulated distillation (SD); and correlating said boiling point distributions to acid molecular weights to determine the TAN.Type: ApplicationFiled: February 7, 2013Publication date: August 22, 2013Applicant: PHILLIPS 66 COMPANYInventors: John Brian Green, Ricky Eugene Snelling, Laura Lee Young, Dale Lee Embry, Herbert Robert Pinnick, Jr.
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Patent number: 8512550Abstract: A method for the determination of optimal pipestill operation comprising the steps of: feeding a crude oil feedstream into the pipestill wherein the crude oil feedstream is separated into boiling range fractions, performing a virtual assay of the crude oil feedstream to determine predicted boiling range fraction yields, comparing the predicted boiling range fraction yields with the actual boiling range fraction yields from the pipestill to determine differences between these fraction yields, relating the difference between the fraction yields with the operation of the pipestill.Type: GrantFiled: August 9, 2005Date of Patent: August 20, 2013Assignee: ExxonMobil Research and Engineering CompanyInventors: Arthur H. Rose, James M. Brown, Gregory M. Martin
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Patent number: 8515685Abstract: A mass spectrometer and a method of spectrometry are disclosed wherein liquid chromatography mass spectral data are probabilistically clustered on the basis of mass to charge ratio and retention time.Type: GrantFiled: May 3, 2005Date of Patent: August 20, 2013Assignee: Micromass UK LimitedInventors: Richard Denny, Keith Richardson
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Patent number: 8510064Abstract: A method for determining a condition indicator of a water analysis apparatus includes determining a respective parameter value for each of at least two different technical parameters of the water analysis apparatus. A respective deviation value of each of the parameter values is determined with respect to an associated respective parameter reference value for each of the technical parameters. A respective deviation relevance value from each of the deviation values is determined using a respective parameter-specific deviation relevance function for each of the parameter values, the parameter-specific deviation relevance functions being different from each other. Using an indicator function, a condition indicator is calculated from the determined deviation relevance values.Type: GrantFiled: March 5, 2010Date of Patent: August 13, 2013Assignee: Hach Lange GmbHInventors: Toon Streppel, Torsten Seehaus, Ulrich Schmitz, Manfred Battefeld, Frank Thomas, Michael Kussmann, Michael Haeck
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Patent number: 8504305Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochlorite, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.Type: GrantFiled: February 23, 2010Date of Patent: August 6, 2013Assignee: Hach CompanyInventor: Thomas D. Wolfe
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Publication number: 20130197818Abstract: A measuring arrangement of the invention includes: At least one measuring device, which generates, repeatedly during operation, measured values, especially digital, measured values, representing the at least one measured variable to be registered; as well as an electronic data processing system superordinated to the at least one measuring device, especially a data processing system which is spatially distributed and/or spatially remote from the measuring device. Measuring device and data processing system are connected together by means of at least two line-pairs, through each of which an electrical current flows, at least at times, during operation. According to the invention, the measuring device transmits the internally generated, measured values to the data processing system via both line-pairs. In this way, it is then possible to transmit a plurality of measured values simultaneously, when each of the two line-pairs is embodied as part of a two-conductor current-loop.Type: ApplicationFiled: December 6, 2012Publication date: August 1, 2013Applicant: ENDRESS + HAUSER FLOWTEC AGInventor: Endress + Hauser Flowtec AG
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Patent number: 8498823Abstract: Methods for generating putative ligand structures capable of altering the activity of a target effector molecule comprise: constructing an elongated monomer of the target effector molecule; constructing a three dimensional model of the target effector molecule under the influence of elongation using empirical three dimensional data, the model including a conformation revealing the binding portion of the target effector molecule to a putative ligand structure; generating a plurality of computational models of the target effector molecule; filtering the plurality of computational models against the three dimensional model created experimentally using a reiterative simulation analysis algorithm operable to identify and select a plurality of computational models having a root-mean square deviation below a predetermined threshold when compared to the three dimensional model of the target effector molecule; screening a plurality of ligands to rank the binding strength of each ligand with the plurality of computatioType: GrantFiled: September 25, 2009Date of Patent: July 30, 2013Assignee: The Regents of The University of MichiganInventors: Hashim M. Al-Hashimi, Andrew Stelzer, Ioan Andricioaei, Aaron Frank
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Patent number: 8486705Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.Type: GrantFiled: March 20, 2012Date of Patent: July 16, 2013Assignee: Momenta Pharmaceuticals, Inc.Inventor: Sasisekharan Raguram
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Patent number: 8489240Abstract: A control system for industrial water systems that utilizes multiple measurements of information and models to decide optimal control actions to maximize corrosion/scaling/fouling inhibition and particulate dispersancy performance and minimize cost of water and treatment chemicals. This system is capable of automatic operation for a wide range of process conditions, ensures multiple performance objectives, achieves robust operation under a variety or un-measurable disturbances and achieves the least costly solution delivery.Type: GrantFiled: August 3, 2007Date of Patent: July 16, 2013Assignee: General Electric CompanyInventors: Zhaoyang Wan, Gary E. Geiger, Yong Zhang, Yu Zhang
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Publication number: 20130179092Abstract: A method for monitoring global crude oil quality. The method includes the steps of obtaining samples of a crude oil having a quality, generating characterization data from measurements of samples of the crude oil, determining values of properties of an assay of the crude oil using the data of step a), storing the values of the properties of the assay in a database, determining deviations of the values of the properties of the assay from the values of the properties of a recommended assay having a quality, determining a statistical significance of the deviations of the values of the properties of the assay from the values of the properties of the recommended assay to determine if the crude oil quality is different from the quality of the recommended assay, and determining if the statistical significance indicates a change in the economic valuation between the assay and the recommended assay.Type: ApplicationFiled: December 17, 2012Publication date: July 11, 2013Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventor: ExxonMobil Research Engineering Company
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Publication number: 20130179091Abstract: The present disclosure is directed to systems and methods for identifying unknown drug targets via adverse event data. An analyzer receives an identification of a first drug having one or more unknown target proteins and identifies a second drug related to the first drug. The analyzer retrieves, from an adverse event database, a first side effect profile associated with the first drug, and a second side effect profile associated with the second drug. The analyzer generates a third side effect profile comprising a subset of the first side effect profile not shared by the second side effect profile, and identifies a third drug having a fourth side effect profile comprising the third side effect profile. The analyzer retrieves a list of one or more target proteins of the third drug not targeted by the second drug, and presents the retrieved list as potential target proteins of the first drug.Type: ApplicationFiled: April 13, 2012Publication date: July 11, 2013Inventors: David Jackson, Theodoros Soldatos, Guillaume Taglang, Alexander Zien, Stephan Brock
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Publication number: 20130166226Abstract: Apparatus, system, method and computer-readable medium for isolating chemical exchange saturation transfer contrast from magnetization transfer asymmetry under two-frequency RF irradiation. A two-pool model for magnetization transfer (MT) can be established fully based on Provotorov's theory of saturation, and then extended to the situation of simultaneous two-frequency RF irradiation. Numerical simulations and experimental results demonstrate that two-frequency RF irradiation can make MT effects independent of irradiation frequency over a wide range, and thus can suppress MT asymmetry. Exemplary embodiments can be provided to isolate chemical exchange saturation transfer (CEST) contrast from MT asymmetry contrast by using the two-frequency RF irradiation technique. A further embodiment can isolate a narrow-frequency spectrum MT mechanism from a broad-frequency spectrum MT mechanism.Type: ApplicationFiled: November 28, 2012Publication date: June 27, 2013Applicant: NEW YORK UNIVERSITYInventor: New York University
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Patent number: 8465984Abstract: The instant disclosure is directed to a method of detecting an emulsion in a turbid brine, the method comprising the steps of disposing an aliquot of the turbid brine into a sample container to produce a test sample; adding one or more drops of a dye solution comprising an oil-soluble dye dissolved in a nonaqueous base fluid to said test sample; and determining the configuration of the dye solution after a period of time on a surface of the test sample, wherein a configuration of the dye solution forming a ring around the perimeter of the sample container at the interface of a wall of the sample container and the turbid brine indicates an emulsion is present in the turbid brine, and wherein a configuration of the dye solution forming a single dot or a plurality of dots on the surface of the turbid brine indicates an emulsion is not present in the turbid brine.Type: GrantFiled: January 25, 2010Date of Patent: June 18, 2013Assignee: M-I L.L.CInventors: Bethicia B. Prasek, Marc A. Churan
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Publication number: 20130143330Abstract: A reaction characteristic detector comprising a ladder assembly including a plurality of rungs, where each rung in the plurality of rungs comprises a reaction passage determiner spaced a distance from a point of an energetic material reaction initiation. Each reaction passage determiner has at least one characteristic that is configured to change in response to the reaction occurring proximate to the reaction passage determiner.Type: ApplicationFiled: December 1, 2011Publication date: June 6, 2013Inventors: Steven J. Apperson, Christopher J. Morris, Luke J. Currano, Collin R. Becker, Madan Dubey
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Publication number: 20130139490Abstract: In one embodiment of the invention, a method for determining an exhaust system condition includes determining if a reaction in an oxidation catalyst is performing acceptably based on a determined temperature of the exhaust gas flowing from the oxidation catalyst and determining a temperature of the exhaust gas flowing from a particulate filter. The method further includes determining a temperature of the exhaust gas flowing into the oxidation catalyst, determining an exhaust system condition based on a first difference between the temperature of the exhaust gas flowing from the particulate filter and the temperature of the exhaust gas flowing from the oxidation catalyst and a second absolute difference between the temperature of the exhaust gas flowing from the oxidation catalyst and the temperature of the exhaust gas flowing into the oxidation catalyst and communicating a signal to identify the determined exhaust system condition.Type: ApplicationFiled: December 1, 2011Publication date: June 6, 2013Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Vincent J. Tylutki, Janean E. Kowalkowski, Benjamin Radke
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Patent number: 8455819Abstract: An ion guide or mass analyser is disclosed comprising a plurality of electrodes having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser. The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages are applied to the electrodes of the ion guide or mass analyser in order to urge ions along the length of the ion guides or mass analyser. The amplitude of the transient DC voltage applied to the electrode may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser in reverse order of their mass to charge ratio.Type: GrantFiled: April 1, 2011Date of Patent: June 4, 2013Assignee: Micromass UK LimitedInventors: Martin Green, Jason Lee Wildgoose, Steven D. Pringle, Daniel James Kenny
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Patent number: 8452548Abstract: In one embodiment a method to determine at least one low temperature property of the lubricant oil is disclosed. This method comprises obtaining a base stock, generating a DSC curve of wax versus temperature using a heating curve for the base stock, correlating the heating curve of the base stock with a MRV for a formulated oil, and determining the MRV of the lubricant oil from the correlation of the base stock to the MRV of the corresponding desired base oil.Type: GrantFiled: September 8, 2009Date of Patent: May 28, 2013Assignee: Exxonmobil Research and Engineering CompanyInventors: Ronald M. Gould, Eugine Choi
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Patent number: 8447527Abstract: A method for matching a precursor ion with one or more related product ions includes providing input data sets obtained from sample injections, each of the data sets including a precursor ion and one or more product ions, normalizing the input data sets in accordance with a single retention time for the precursor ion, determining which product ions are within a predetermined retention time window with respect to the single retention time, and, if a product ion is within the predetermined retention time window for a specified number of the input data sets, determining that the product ion is related to the precursor having the single retention time. An apparatus for analyzing a sample includes a chromatography module, a mass-spectrometry module in communication with the chromatography module, and control unit in communication with the chromatography module and the mass-spectrometry module.Type: GrantFiled: March 14, 2012Date of Patent: May 21, 2013Assignee: Waters Technologies CorporationInventors: Marc V. Gorenstein, Scott J. Geromanos, Jeffrey Cruz Silva, Guo-Zhong Li
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Patent number: 8433723Abstract: In various embodiments, multiple heterogeneous documents are processed to identify structures, such as chemical structures, contained therein, including non-embedded structures. Also described is a graphical user interface that permits a user to search for a structure or substructure within a set of electronic documents, then displays the matching structures as well as the actual pages of the documents on which the matching structures are found. Display of the actual pages allows the user to verify the matches and provides helpful context for the user.Type: GrantFiled: May 3, 2011Date of Patent: April 30, 2013Assignee: Cambridgesoft CorporationInventors: Robin Y. Smith, William B. Ballard, Scott G. Flicker, Sean G. Greenhow
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Publication number: 20130096845Abstract: An apparatus comprising: a value receiver, configured to receive fluorescence values measured during a chemical reaction involving a test sample, each value pertaining to a respective physical parameter value, a difference calculator, configured to calculate differences, each difference being between respective one of the measured fluorescence values and one of reference fluorescence values of a reference sample, each reference fluorescence value pertaining to a respective physical parameter value, a cumulative index calculator, configured to calculate a cumulative index, by selecting a first difference among the calculated differences, and selecting and adding to the first difference differences, each one of the added differences being selected according to a proximity standard applied on each two differences selected in a sequence, the proximity standard being based on proximity of physical parameter values and difference size, and a similarity determiner, configured to determine similarity between the sampType: ApplicationFiled: October 14, 2011Publication date: April 18, 2013Inventor: Ze'ev RUSSAK
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Publication number: 20130090865Abstract: Disclosed is a method for electronic residual spectroscopy for atomic-scaled surface and sub-surface information purification. The method comprises collecting at least one reference spectrum and a plurality of spectra under various conditions. The background of all the plurality of spectra is then subtracted and the plurality of spectra are normalized. Subtracting the reference spectrum from the normalized plurality of spectra will give atomic-scaled, meaningful information at selected zones.Type: ApplicationFiled: June 18, 2010Publication date: April 11, 2013Applicant: NANYANG TECHNOLOGICAL UNIVERSITYInventor: Changqing Sun
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Patent number: 8417467Abstract: According to one embodiment, a method for estimating an activity of one or more radio-nuclides includes receiving one or more templates, the one or more templates corresponding to one or more radio-nuclides which contribute to a probable solution, receiving one or more weighting factors, each weighting factor representing a contribution of one radio-nuclide to the probable solution, computing an effective areal density for each of the one more radio-nuclides, computing an effective atomic number (Z) for each of the one more radio-nuclides, computing an effective metric for each of the one or more radio-nuclides, and computing an estimated activity for each of the one or more radio-nuclides. In other embodiments, computer program products, systems, and other methods are presented for estimating an activity of one or more radio-nuclides.Type: GrantFiled: April 29, 2010Date of Patent: April 9, 2013Assignee: Lawrence Livermore National Security, LLCInventor: Karl Einar Nelson
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Publication number: 20130073221Abstract: Techniques for identifying a composition of a target fluid using a set of vectors representing known residue patterns for a two or more fluids including said target fluid is provided. An exemplary method includes storing one or more digital measurements of residue for the target fluid, extracting one or more descriptive features from the measurements; and processing descriptive features to identify the composition of the target fluid. The processing includes using a machine learning algorithm trained with data linking residue morphology to fluid composition. A distance between a vector representing said one or more descriptive features and said set of vectors representing known residue patterns is determined, and a residue is assigned to one or more of the known residue patterns.Type: ApplicationFiled: September 14, 2012Publication date: March 21, 2013Inventors: Daniel Attinger, Frederic Zenhausern, Cedric Hurth, Shih-Fu Chang, Zhenguo Li
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Patent number: 8386194Abstract: The condition of a bond surface is determined. A 3-D wettability tension curve is generated for the bond surface which represents a range of possible wettings of an adhesive on the bond surface that may result in a bond joint of acceptable quality. At least three surface energies on the bond surface are measured, and the wettability curve is used to determine whether the condition of the bond surface is acceptable based on the measured bonding surface energies.Type: GrantFiled: June 24, 2010Date of Patent: February 26, 2013Assignee: The Boeing CompanyInventors: Joel P. Baldwin, Russell L. Keller, Eugene Dan-Jumbo
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Publication number: 20130035873Abstract: A method for supervising a process for producing a metal alloy object with a known chemical composition. A resistivity of the metal alloy object is determined. A content of dissolved alloying elements in the metal alloy object is estimated based on the determined resistivity and the chemical composition of the metal alloy object. A content of precipitated alloying elements in the metal alloy object is estimated based on the determined resistivity and the chemical composition of the metal alloy object. The production process is supervised based on a ratio between the estimated content of dissolved alloying elements and the estimated content of precipitated alloying elements.Type: ApplicationFiled: August 15, 2012Publication date: February 7, 2013Applicant: ABB ABInventors: Sten Linder, Lennart Thegel
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Patent number: 8370082Abstract: A method for predicting a physical property of a residue obtainable from a crude oil by a process of distillation, wherein the conditions during the process are represented by a processing parameter, is disclosed. The method includes the steps of: a) using a spectroscopic technique to acquire a spectrum for the crude oil; and b) applying a predictive model based upon a correlation between the spectrum, the physical property and the processing parameter. The method may be used to predict the suitability of crude oil for bitumen production.Type: GrantFiled: April 25, 2008Date of Patent: February 5, 2013Assignee: Shell Oil CompanyInventors: Peter De Peinder, Fred Adrianus Johannes Singelenberg, Tom Visser, Bert Marc Weckhuysen
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Publication number: 20130030719Abstract: Methods and systems for identifying a quantitation cycle (Cq) for a PCR reaction that includes fitting a line having a plurality of line segments to data points associated with a PCR amplification reaction. The data points include a cycle value associated with a PCR cycle and a product value associated with a PCR product. A baseline is identified and reaction segment associated with an exponential region of the PCR reaction is also identified. The reaction segment includes a subset of the plurality of line segments having a slope not less than a steepness criterion. A reaction line is fit to the data points associated with the reaction segment. The Cq is identified by calculating the cycle value for a data point defining the intersection of the baseline and reaction line.Type: ApplicationFiled: July 27, 2012Publication date: January 31, 2013Applicant: THERMO FISHER SCIENTIFIC OYInventors: Jorma Mustola, Antti Koski
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Patent number: 8364316Abstract: A method of modeling phase characteristics of thermodynamic systems utilizing pseudo-properties strategy and a reduced number of variables is disclosed herein. The method describes a means of determining the probability of phase splitting of mixtures of materials at a given temperature, pressure, and composition by characterizing the functions that describe the system via pseudo-properties, and also by describing the system in n?1 or fewer variables, where n represents the number of components in the system of interest. In an embodiment, a multi-component system is characterized in one variable, thereby providing simplified thermodynamic models in a time-efficient manner. In addition, the information generated by this reduced-variable calculation can further be used as a starting point for calculations of equations of state.Type: GrantFiled: September 15, 2009Date of Patent: January 29, 2013Assignee: Invensys Systems, Inc.Inventors: Gang Xu, David Bluck
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Patent number: 8362415Abstract: A method of analyzing biological material by exposing the biological material to a recognition element, that is coupled to a mass tag element, directing an ion beam of a mass spectrometer to the biological material, interrogating at least one region of interest area from the biological material and producing data, and distributing the data in plots.Type: GrantFiled: May 26, 2010Date of Patent: January 29, 2013Assignees: Lawrence Livermore National Security, LLC, Lawrence Berkeley National LaboratoryInventors: James S. Felton, Kuang Jen J. Wu, Mark G. Knize, Kristen S. Kulp, Joe W. Gray
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Patent number: 8364423Abstract: Chemical compositions in the blood may be selectively or preferentially excited by the application of scores comprising a series of at least four energy inputs to a blood vessel.Type: GrantFiled: June 3, 2011Date of Patent: January 29, 2013Assignee: The Invention Science Fund I, LLCInventors: Muriel Y. Ishikawa, Edward K. Y. Jung, Nathan P. Myhrvold, Lowell L. Wood, Jr.
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Patent number: 8357301Abstract: Herein is reported a method for determining whether a re-useable chromatography column packing, which is used at least for the second time in a purification step of a purification of a polypeptide, has reduced separation efficacy in said purification step of said purification of said polypeptide, comprising the following steps: a) identifying and determining the experimental data of an inert change of at least one physicochemical parameter of a mobile phase passing through said re-useable chromatography column packing, b) determining the parameters of a function of formula I by fitting the experimental data of the inert change of the physicochemical parameter of the at least second use, c) determining the difference between the experimental data of the inert change of the physicochemical parameter of the at least second use and the function of formula I with the parameters determined in step b), d) calculating the difference between the maximum value and the minimum value of the difference determined in stepType: GrantFiled: June 22, 2010Date of Patent: January 22, 2013Assignee: Hoffmann-La Roche, Inc.Inventors: Anton Belousov, Thomas Dams, Benjamin Gerwat
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Patent number: 8359168Abstract: The present invention relates to a fuel identification system and method normally applied to internal combustion engine vehicles of the flex-fuel type by means of which it is possible to identify the composition of the fuel used at each point in time, particularly the ratio used in a gasoline/ethanol blend or detect the presence of air or fuel in the vapor state in the fuel line, using the same device that heats the fuel.Type: GrantFiled: July 14, 2008Date of Patent: January 22, 2013Assignee: Robert Bosch LimitadaInventors: Fernando Lepsch, Marcos Melo Araujo, Hilton Rafael Spiler, Carlos Henrique De Oliveira Melo, Hans Hugo Eichel, Jr.
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Publication number: 20130018599Abstract: A graphene nano-sensor with a suspended graphene flake electrically connected to metal electrodes. The graphene nano-sensor is capable of detecting single molecules in an atmosphere through a change in electrical conductance through the graphene flake.Type: ApplicationFiled: July 12, 2012Publication date: January 17, 2013Inventor: Haibing Peng
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Publication number: 20130018593Abstract: Systems and methods are provided for analyzing data to determine properties of a PCR process or other process exhibiting amplification or growth. Data representing an amplification can be distinguished from data representing a jump or other error. A modified sigmoid function containing a drift term may be used in determining the properties. A multi-stage functional fit of the amplification data can provide increased accuracy and consistency of one or more of the properties. A baseline of the amplification data can be determined by analyzing an integrated area of a first derivative function of the data. A reference quantitation value can also be determined from locations of maxima of different derivative functions of the amplification data, e.g., a weighted average of the maxima locations for the second and third derivatives may be used.Type: ApplicationFiled: September 24, 2012Publication date: January 17, 2013Applicant: Bio-Rad Laboratories, Inc.Inventor: Bio-Rad Laboratories, Inc.
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Publication number: 20130009781Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochloritc, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.Type: ApplicationFiled: September 14, 2012Publication date: January 10, 2013Applicant: HACH COMPANYInventor: Thomas D. Wolfe
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Publication number: 20130013218Abstract: According to various embodiments, package evaluation systems and methods are provided for evaluating the sustainability of packaging used in the shipment of goods. In particular, the package evaluation systems and methods are configured for performing package evaluations and managing and providing access to data resulting from package evaluations. The package evaluations are designed to assess, among other things, the ability of sample packages to prevent damage to their contents, the volumetric efficiency of sample packages, and the sustainability of the materials used to construct sample packages. In addition, the systems and methods are further configured for assigning a certification to an entity associated with the evaluated packages based on the results of the evaluation.Type: ApplicationFiled: September 13, 2012Publication date: January 10, 2013Applicant: UNITED PARCEL SERVICE OF AMERICA, INC.Inventors: Arnold Barlow, Dennis R. Estep, Andrew J. Gruber, Patrick McDavid, Quinto Marini, Nancy Parmer
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Publication number: 20130008149Abstract: Systems and methods for estimating an efficiency of a catalyst placed in an exhaust path of a combustion engine are disclosed. In one example approach, a method comprises: ageing the catalyst consecutively at different temperatures for definite time periods; measuring the catalyst conversion efficiency after each ageing step; calculating the ageing factor for each step of the ageing procedure and the accumulative value of the ageing factors for all steps of the ageing procedure; estimating catalyst efficiency correlation factors related to the measured catalyst conversion efficiency for each temperature point and for all ageing conditions; determining a correlation between the catalyst efficiency correlation factors and the accumulative value of the ageing factors; and calculating the conversion efficiency of the aged catalyst based on a predetermined correlation between the accumulative ageing factor and the catalyst efficiency correlation factor.Type: ApplicationFiled: June 28, 2012Publication date: January 10, 2013Applicant: FORD GLOBAL TECHNOLOGIES, LLCInventors: Robert Ukropec, Alexey A. Dubkov, Yasser Mohamed Sayed Yacoub, Albert N. Chigapov, Nina Shishkina, Brendan Patrick Carberry
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Patent number: RE44345Abstract: Apparatuses and methods providing data such as, for example, calibration and reagent information (30) over a network (6) to a measurement apparatus (4) which makes use of a consumable reagent (18) in a measuring process are disclosed. The present invention permits a measurement apparatus (4) to download the necessary code assignment (24) and calibration data (32) of the consumable reagent (18) by means of an electronic communication protocol from a host (33). The host (33) can be a software application running on a host computer (34), another measurement apparatus (50, 58) with or without a code-key slot used to read a memory device providing the above mentioned information (30), a dedicated connectivity device, such as a docking station (44), a portable memory reader (48), a remote computer (54), and combinations thereof.Type: GrantFiled: May 16, 2006Date of Patent: July 9, 2013Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.Inventors: Friedrich Karl Ackermann, Manfred Augstein, Timothy L. Beck, Markus Stephan Fuerst, Robert Lawrence Meek, Philip Edgar Pash, Blaine Edward Ramey, Robert Paul Sabo, Matthew Carlyle Sauers, Joerg Schreiber, Wolfgang Walter, Seth Faulkner Williams, Frederick Leland Wittekind, III