Chemical Property Analysis Patents (Class 702/30)
  • Publication number: 20130304397
    Abstract: A method of measuring a capacitance (C) of a sensor having a working electrode that is coated by an insulating layer and a ligand forming an affinity surface. The method involves the steps of bringing the electrode into contact with an analyte, supplying a constant first current (I1), and a constant second current (I2) of opposite direction to the first current (I1), and a constant third current (I3) of same direction as the first current (I1) during determined time periods to the sensor. Further the method includes sampling the potential (V) built up across the sensor, and calculating the capacitance of the sensor from the inclination (B, D, F, H) of a potential curve received in response to the current supply. A method used for detection of an interaction between a ligand and an analyte is also disclosed.
    Type: Application
    Filed: October 31, 2011
    Publication date: November 14, 2013
    Applicant: CAPSENZE HB
    Inventors: Dag Erlandsson, Martin Hedstrom, Bo Mattiasson, Joakim Larsson
  • Publication number: 20130297228
    Abstract: Disclosed is a method of measuring radioactive material of an ingot, in which an ingot having a volume produced by subjecting metal waste generated in nuclear fuel processing or production facilities to melting decontamination undergoes gamma spectroscopy using a NaI detector to measure gamma rays of U-235 (185.72 keV, 57.2%) among uranium isotopes, followed by performing detector calibration using a certified reference material and self-absorption correction depending on the density of a medium using MCNP computer code, and which enables rapid determination of whether the ingot subjected to melting decontamination may be self-disposed of or not.
    Type: Application
    Filed: April 30, 2013
    Publication date: November 7, 2013
    Applicant: KEPCO NUCLEAR FUEL CO., LTD.
    Inventors: Suk Ju CHO, Young Bae LEE, Jeung Gun SEOL, Yong Jae KIM, Jae Bong RYU
  • Publication number: 20130297229
    Abstract: Disclosed is a method of measuring radioactive material of an ingot, in which an ingot having a volume produced by subjecting metal waste generated in nuclear fuel processing or production facilities to melting decontamination undergoes gamma spectroscopy using a HPGe detector to measure gamma rays of U-235 (185.72 key, 57.2%) among uranium isotopes, followed by performing detector calibration using a certified reference material and self-absorption correction depending on the density of a medium using MCNP computer code, and which enables rapid determination of whether the ingot subjected to melting decontamination may be self-disposed of or not.
    Type: Application
    Filed: April 30, 2013
    Publication date: November 7, 2013
    Applicant: KEPCO NUCLEAR FUEL CO., LTD.
    Inventor: KEPCO NUCLEAR FUEL CO., LTD.
  • Patent number: 8577623
    Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochloritc, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 5, 2013
    Assignee: Hach Company
    Inventor: Thomas D. Wolfe
  • Publication number: 20130288379
    Abstract: A method of producing an alkylene oxide includes passing a reaction mixture comprising alkylene, oxygen and a gaseous chlorine-containing promoter species over a supported catalyst containing silver and a promoting amount of rhenium to undergo an epoxidation reaction at a first operating condition. The method further includes subsequently performing the epoxidation reaction at a preferred operating condition. The preferred operating condition is characterized by an efficiency of the epoxidation reaction toward the alkylene oxide where the efficiency is lower than that of a maximum efficiency achievable at an operating temperature corresponding to the preferred operating condition.
    Type: Application
    Filed: June 27, 2013
    Publication date: October 31, 2013
    Inventors: Michael Habenschuss, Hwaili Soo, Paul V. Hinman, Albert C. Liu
  • Patent number: 8571812
    Abstract: A method for determining the oxygen concentration of a sample made of a semiconductor material includes a heat treatment step of the sample to form thermal donors, the measurement of the resistivity in an area of the sample, the determination of the thermal donor concentration from a relation expressing the charge carrier mobility according to an ionized dopant impurity concentration, by adding to the dopant impurity concentration four times the thermal donor concentration, and from the measured resistivity value. The method finally includes determining the oxygen concentration from the thermal donor concentration.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: October 29, 2013
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Jordi Veirman, Sebastien Dubois, Nicolas Enjalbert
  • Patent number: 8569045
    Abstract: Provided are a water toxicity detecting apparatus and a method using sulfur particles.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: October 29, 2013
    Assignee: University-Industry Cooperation Foundation, Kangwon University
    Inventor: Sang Eun Oh
  • Publication number: 20130270492
    Abstract: In a method of preparing a liquid solution by mixing ingredients according to a predetermined recipe, wherein at least one pair of species of the liquid solution is derived from a weak electrolyte and corresponds to an acid-base pair, the conductivity of the liquid solution is predicted by: (i) for each pair of species derived from a weak electrolyte, solving a respective equilibrium equation to calculate the actual molar concentration of each such species at equilibrium in the liquid solution, (ii) calculating for each ionic species of said plurality of species the molar conductivity by the formula: ?=?0?K×Sqrt(c) wherein ? is the molar conductivity, ?0 is the molar conductivity at infinite dilution, c is the concentration, and K is the Kohlrausch coefficient, and wherein K and ?0 are predetermined values for K and ?0 for each ionic species, (iii) calculating the conductivity x for each ionic species by the formula: ?=c×? and (iv) adding up the conductivities determined in step (iii) for
    Type: Application
    Filed: December 15, 2011
    Publication date: October 17, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventor: Enrique Carredano
  • Publication number: 20130267034
    Abstract: A measuring method of an intermolecular interaction for optically measuring an intermolecular interaction between a plurality of substances on a thin film, the method comprising: detecting intensity at a first wavelength of reflected light or transmitted light before start of the intermolecular interaction with a detection unit which detects the reflected light from the thin film or the transmitted light transmitted through the thin film; detecting intensity at the first wavelength of the reflected light or the transmitted light after the start of the intermolecular interaction with the detection unit; and calculating a difference in intensity of the reflected light or the transmitted light at the first wavelength between before and after the start of the intermolecular interaction.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 10, 2013
    Inventors: Naoki Izumiya, Yuka Yoshihara
  • Publication number: 20130261986
    Abstract: An object of the present invention is to provide a method for rapidly and accurately determining the lipophilicity of a wide variety of substances.
    Type: Application
    Filed: December 26, 2011
    Publication date: October 3, 2013
    Applicant: ASTELLAS PHARMA INC.
    Inventors: Ryo Mizoguchi, Katsuhiko Gato
  • Publication number: 20130238255
    Abstract: A system for managing a concrete delivery vehicle having a mixing drum 14 and hydraulic drive 16 for rotating the mixing drum, including a rotational sensor 20 configured to sense a rotational speed of the mixing drum, a hydraulic sensor 22 coupled to the hydraulic drive and configured to sense a hydraulic pressure required to turn the mixing drum, a temperature sensor for sensing temperature of the drum, and a communications port 26 configured to communicate a slump calculation to a status system 28 commonly used in the concrete industry, wherein the sensing of the rotational speed of the mixing drum is used to qualify a calculation of current slump based on the hydraulic pressure required to turn the mixing drum. Temperature readings are further used to qualify or evaluate a load. Also, water purge connections facilitate cold weather operation.
    Type: Application
    Filed: April 30, 2013
    Publication date: September 12, 2013
    Applicant: VERIFI LLC
    Inventors: Roy Cooley, John I. Compton, Michael Topputo, Steve Verdino, Jerold Brickler
  • Patent number: 8521442
    Abstract: An exemplary method for measuring the electrical resistance and/or electrical conductivity of solutions, includes: exciting the electrodes with a rectangular shaped, alternating current of a certain frequency fH through a connecting cable; synchronously rectifying a voltage of the electrodes of the measuring cell in response to the alternating current, calculating a first average voltage, dividing the first average voltage by the current amplitude to obtain a first impedance RH; then exciting the electrodes with a rectangular shaped, alternating current of another frequency fL through the connecting cable; synchronously rectifying the voltage of the electrodes in response to the alternating current, calculating a second average voltage, and dividing the second average voltage by the current amplitude to obtain a second impedance RL.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: August 27, 2013
    Assignee: Mettler-Toledo AG
    Inventor: Changlin Wang
  • Publication number: 20130218481
    Abstract: There is provided a method for determining Total Acid Number (TAN) in a fluid fossil fuel, such as a crude oil, comprising: separating said fluid fossil fuel by liquid chromatography into a plurality of fractions, comprising at least one acidic fraction; determining boiling point distribution of said crude oil, of said acidic fraction, and of said polyacidic fraction by simulated distillation (SD); and correlating said boiling point distributions to acid molecular weights to determine the TAN.
    Type: Application
    Filed: February 7, 2013
    Publication date: August 22, 2013
    Applicant: PHILLIPS 66 COMPANY
    Inventors: John Brian Green, Ricky Eugene Snelling, Laura Lee Young, Dale Lee Embry, Herbert Robert Pinnick, Jr.
  • Patent number: 8512550
    Abstract: A method for the determination of optimal pipestill operation comprising the steps of: feeding a crude oil feedstream into the pipestill wherein the crude oil feedstream is separated into boiling range fractions, performing a virtual assay of the crude oil feedstream to determine predicted boiling range fraction yields, comparing the predicted boiling range fraction yields with the actual boiling range fraction yields from the pipestill to determine differences between these fraction yields, relating the difference between the fraction yields with the operation of the pipestill.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: August 20, 2013
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Arthur H. Rose, James M. Brown, Gregory M. Martin
  • Patent number: 8515685
    Abstract: A mass spectrometer and a method of spectrometry are disclosed wherein liquid chromatography mass spectral data are probabilistically clustered on the basis of mass to charge ratio and retention time.
    Type: Grant
    Filed: May 3, 2005
    Date of Patent: August 20, 2013
    Assignee: Micromass UK Limited
    Inventors: Richard Denny, Keith Richardson
  • Patent number: 8510064
    Abstract: A method for determining a condition indicator of a water analysis apparatus includes determining a respective parameter value for each of at least two different technical parameters of the water analysis apparatus. A respective deviation value of each of the parameter values is determined with respect to an associated respective parameter reference value for each of the technical parameters. A respective deviation relevance value from each of the deviation values is determined using a respective parameter-specific deviation relevance function for each of the parameter values, the parameter-specific deviation relevance functions being different from each other. Using an indicator function, a condition indicator is calculated from the determined deviation relevance values.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: August 13, 2013
    Assignee: Hach Lange GmbH
    Inventors: Toon Streppel, Torsten Seehaus, Ulrich Schmitz, Manfred Battefeld, Frank Thomas, Michael Kussmann, Michael Haeck
  • Patent number: 8504305
    Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochlorite, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: August 6, 2013
    Assignee: Hach Company
    Inventor: Thomas D. Wolfe
  • Publication number: 20130197818
    Abstract: A measuring arrangement of the invention includes: At least one measuring device, which generates, repeatedly during operation, measured values, especially digital, measured values, representing the at least one measured variable to be registered; as well as an electronic data processing system superordinated to the at least one measuring device, especially a data processing system which is spatially distributed and/or spatially remote from the measuring device. Measuring device and data processing system are connected together by means of at least two line-pairs, through each of which an electrical current flows, at least at times, during operation. According to the invention, the measuring device transmits the internally generated, measured values to the data processing system via both line-pairs. In this way, it is then possible to transmit a plurality of measured values simultaneously, when each of the two line-pairs is embodied as part of a two-conductor current-loop.
    Type: Application
    Filed: December 6, 2012
    Publication date: August 1, 2013
    Applicant: ENDRESS + HAUSER FLOWTEC AG
    Inventor: Endress + Hauser Flowtec AG
  • Patent number: 8498823
    Abstract: Methods for generating putative ligand structures capable of altering the activity of a target effector molecule comprise: constructing an elongated monomer of the target effector molecule; constructing a three dimensional model of the target effector molecule under the influence of elongation using empirical three dimensional data, the model including a conformation revealing the binding portion of the target effector molecule to a putative ligand structure; generating a plurality of computational models of the target effector molecule; filtering the plurality of computational models against the three dimensional model created experimentally using a reiterative simulation analysis algorithm operable to identify and select a plurality of computational models having a root-mean square deviation below a predetermined threshold when compared to the three dimensional model of the target effector molecule; screening a plurality of ligands to rank the binding strength of each ligand with the plurality of computatio
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: July 30, 2013
    Assignee: The Regents of The University of Michigan
    Inventors: Hashim M. Al-Hashimi, Andrew Stelzer, Ioan Andricioaei, Aaron Frank
  • Patent number: 8486705
    Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: July 16, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventor: Sasisekharan Raguram
  • Patent number: 8489240
    Abstract: A control system for industrial water systems that utilizes multiple measurements of information and models to decide optimal control actions to maximize corrosion/scaling/fouling inhibition and particulate dispersancy performance and minimize cost of water and treatment chemicals. This system is capable of automatic operation for a wide range of process conditions, ensures multiple performance objectives, achieves robust operation under a variety or un-measurable disturbances and achieves the least costly solution delivery.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: July 16, 2013
    Assignee: General Electric Company
    Inventors: Zhaoyang Wan, Gary E. Geiger, Yong Zhang, Yu Zhang
  • Publication number: 20130179092
    Abstract: A method for monitoring global crude oil quality. The method includes the steps of obtaining samples of a crude oil having a quality, generating characterization data from measurements of samples of the crude oil, determining values of properties of an assay of the crude oil using the data of step a), storing the values of the properties of the assay in a database, determining deviations of the values of the properties of the assay from the values of the properties of a recommended assay having a quality, determining a statistical significance of the deviations of the values of the properties of the assay from the values of the properties of the recommended assay to determine if the crude oil quality is different from the quality of the recommended assay, and determining if the statistical significance indicates a change in the economic valuation between the assay and the recommended assay.
    Type: Application
    Filed: December 17, 2012
    Publication date: July 11, 2013
    Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventor: ExxonMobil Research Engineering Company
  • Publication number: 20130179091
    Abstract: The present disclosure is directed to systems and methods for identifying unknown drug targets via adverse event data. An analyzer receives an identification of a first drug having one or more unknown target proteins and identifies a second drug related to the first drug. The analyzer retrieves, from an adverse event database, a first side effect profile associated with the first drug, and a second side effect profile associated with the second drug. The analyzer generates a third side effect profile comprising a subset of the first side effect profile not shared by the second side effect profile, and identifies a third drug having a fourth side effect profile comprising the third side effect profile. The analyzer retrieves a list of one or more target proteins of the third drug not targeted by the second drug, and presents the retrieved list as potential target proteins of the first drug.
    Type: Application
    Filed: April 13, 2012
    Publication date: July 11, 2013
    Inventors: David Jackson, Theodoros Soldatos, Guillaume Taglang, Alexander Zien, Stephan Brock
  • Publication number: 20130166226
    Abstract: Apparatus, system, method and computer-readable medium for isolating chemical exchange saturation transfer contrast from magnetization transfer asymmetry under two-frequency RF irradiation. A two-pool model for magnetization transfer (MT) can be established fully based on Provotorov's theory of saturation, and then extended to the situation of simultaneous two-frequency RF irradiation. Numerical simulations and experimental results demonstrate that two-frequency RF irradiation can make MT effects independent of irradiation frequency over a wide range, and thus can suppress MT asymmetry. Exemplary embodiments can be provided to isolate chemical exchange saturation transfer (CEST) contrast from MT asymmetry contrast by using the two-frequency RF irradiation technique. A further embodiment can isolate a narrow-frequency spectrum MT mechanism from a broad-frequency spectrum MT mechanism.
    Type: Application
    Filed: November 28, 2012
    Publication date: June 27, 2013
    Applicant: NEW YORK UNIVERSITY
    Inventor: New York University
  • Patent number: 8465984
    Abstract: The instant disclosure is directed to a method of detecting an emulsion in a turbid brine, the method comprising the steps of disposing an aliquot of the turbid brine into a sample container to produce a test sample; adding one or more drops of a dye solution comprising an oil-soluble dye dissolved in a nonaqueous base fluid to said test sample; and determining the configuration of the dye solution after a period of time on a surface of the test sample, wherein a configuration of the dye solution forming a ring around the perimeter of the sample container at the interface of a wall of the sample container and the turbid brine indicates an emulsion is present in the turbid brine, and wherein a configuration of the dye solution forming a single dot or a plurality of dots on the surface of the turbid brine indicates an emulsion is not present in the turbid brine.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: June 18, 2013
    Assignee: M-I L.L.C
    Inventors: Bethicia B. Prasek, Marc A. Churan
  • Publication number: 20130143330
    Abstract: A reaction characteristic detector comprising a ladder assembly including a plurality of rungs, where each rung in the plurality of rungs comprises a reaction passage determiner spaced a distance from a point of an energetic material reaction initiation. Each reaction passage determiner has at least one characteristic that is configured to change in response to the reaction occurring proximate to the reaction passage determiner.
    Type: Application
    Filed: December 1, 2011
    Publication date: June 6, 2013
    Inventors: Steven J. Apperson, Christopher J. Morris, Luke J. Currano, Collin R. Becker, Madan Dubey
  • Publication number: 20130139490
    Abstract: In one embodiment of the invention, a method for determining an exhaust system condition includes determining if a reaction in an oxidation catalyst is performing acceptably based on a determined temperature of the exhaust gas flowing from the oxidation catalyst and determining a temperature of the exhaust gas flowing from a particulate filter. The method further includes determining a temperature of the exhaust gas flowing into the oxidation catalyst, determining an exhaust system condition based on a first difference between the temperature of the exhaust gas flowing from the particulate filter and the temperature of the exhaust gas flowing from the oxidation catalyst and a second absolute difference between the temperature of the exhaust gas flowing from the oxidation catalyst and the temperature of the exhaust gas flowing into the oxidation catalyst and communicating a signal to identify the determined exhaust system condition.
    Type: Application
    Filed: December 1, 2011
    Publication date: June 6, 2013
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Vincent J. Tylutki, Janean E. Kowalkowski, Benjamin Radke
  • Patent number: 8455819
    Abstract: An ion guide or mass analyser is disclosed comprising a plurality of electrodes having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser. The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages are applied to the electrodes of the ion guide or mass analyser in order to urge ions along the length of the ion guides or mass analyser. The amplitude of the transient DC voltage applied to the electrode may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser in reverse order of their mass to charge ratio.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: June 4, 2013
    Assignee: Micromass UK Limited
    Inventors: Martin Green, Jason Lee Wildgoose, Steven D. Pringle, Daniel James Kenny
  • Patent number: 8452548
    Abstract: In one embodiment a method to determine at least one low temperature property of the lubricant oil is disclosed. This method comprises obtaining a base stock, generating a DSC curve of wax versus temperature using a heating curve for the base stock, correlating the heating curve of the base stock with a MRV for a formulated oil, and determining the MRV of the lubricant oil from the correlation of the base stock to the MRV of the corresponding desired base oil.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: May 28, 2013
    Assignee: Exxonmobil Research and Engineering Company
    Inventors: Ronald M. Gould, Eugine Choi
  • Patent number: 8447527
    Abstract: A method for matching a precursor ion with one or more related product ions includes providing input data sets obtained from sample injections, each of the data sets including a precursor ion and one or more product ions, normalizing the input data sets in accordance with a single retention time for the precursor ion, determining which product ions are within a predetermined retention time window with respect to the single retention time, and, if a product ion is within the predetermined retention time window for a specified number of the input data sets, determining that the product ion is related to the precursor having the single retention time. An apparatus for analyzing a sample includes a chromatography module, a mass-spectrometry module in communication with the chromatography module, and control unit in communication with the chromatography module and the mass-spectrometry module.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: May 21, 2013
    Assignee: Waters Technologies Corporation
    Inventors: Marc V. Gorenstein, Scott J. Geromanos, Jeffrey Cruz Silva, Guo-Zhong Li
  • Patent number: 8433723
    Abstract: In various embodiments, multiple heterogeneous documents are processed to identify structures, such as chemical structures, contained therein, including non-embedded structures. Also described is a graphical user interface that permits a user to search for a structure or substructure within a set of electronic documents, then displays the matching structures as well as the actual pages of the documents on which the matching structures are found. Display of the actual pages allows the user to verify the matches and provides helpful context for the user.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: April 30, 2013
    Assignee: Cambridgesoft Corporation
    Inventors: Robin Y. Smith, William B. Ballard, Scott G. Flicker, Sean G. Greenhow
  • Publication number: 20130096845
    Abstract: An apparatus comprising: a value receiver, configured to receive fluorescence values measured during a chemical reaction involving a test sample, each value pertaining to a respective physical parameter value, a difference calculator, configured to calculate differences, each difference being between respective one of the measured fluorescence values and one of reference fluorescence values of a reference sample, each reference fluorescence value pertaining to a respective physical parameter value, a cumulative index calculator, configured to calculate a cumulative index, by selecting a first difference among the calculated differences, and selecting and adding to the first difference differences, each one of the added differences being selected according to a proximity standard applied on each two differences selected in a sequence, the proximity standard being based on proximity of physical parameter values and difference size, and a similarity determiner, configured to determine similarity between the samp
    Type: Application
    Filed: October 14, 2011
    Publication date: April 18, 2013
    Inventor: Ze'ev RUSSAK
  • Publication number: 20130090865
    Abstract: Disclosed is a method for electronic residual spectroscopy for atomic-scaled surface and sub-surface information purification. The method comprises collecting at least one reference spectrum and a plurality of spectra under various conditions. The background of all the plurality of spectra is then subtracted and the plurality of spectra are normalized. Subtracting the reference spectrum from the normalized plurality of spectra will give atomic-scaled, meaningful information at selected zones.
    Type: Application
    Filed: June 18, 2010
    Publication date: April 11, 2013
    Applicant: NANYANG TECHNOLOGICAL UNIVERSITY
    Inventor: Changqing Sun
  • Patent number: 8417467
    Abstract: According to one embodiment, a method for estimating an activity of one or more radio-nuclides includes receiving one or more templates, the one or more templates corresponding to one or more radio-nuclides which contribute to a probable solution, receiving one or more weighting factors, each weighting factor representing a contribution of one radio-nuclide to the probable solution, computing an effective areal density for each of the one more radio-nuclides, computing an effective atomic number (Z) for each of the one more radio-nuclides, computing an effective metric for each of the one or more radio-nuclides, and computing an estimated activity for each of the one or more radio-nuclides. In other embodiments, computer program products, systems, and other methods are presented for estimating an activity of one or more radio-nuclides.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: April 9, 2013
    Assignee: Lawrence Livermore National Security, LLC
    Inventor: Karl Einar Nelson
  • Publication number: 20130073221
    Abstract: Techniques for identifying a composition of a target fluid using a set of vectors representing known residue patterns for a two or more fluids including said target fluid is provided. An exemplary method includes storing one or more digital measurements of residue for the target fluid, extracting one or more descriptive features from the measurements; and processing descriptive features to identify the composition of the target fluid. The processing includes using a machine learning algorithm trained with data linking residue morphology to fluid composition. A distance between a vector representing said one or more descriptive features and said set of vectors representing known residue patterns is determined, and a residue is assigned to one or more of the known residue patterns.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Inventors: Daniel Attinger, Frederic Zenhausern, Cedric Hurth, Shih-Fu Chang, Zhenguo Li
  • Patent number: 8386194
    Abstract: The condition of a bond surface is determined. A 3-D wettability tension curve is generated for the bond surface which represents a range of possible wettings of an adhesive on the bond surface that may result in a bond joint of acceptable quality. At least three surface energies on the bond surface are measured, and the wettability curve is used to determine whether the condition of the bond surface is acceptable based on the measured bonding surface energies.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: February 26, 2013
    Assignee: The Boeing Company
    Inventors: Joel P. Baldwin, Russell L. Keller, Eugene Dan-Jumbo
  • Publication number: 20130035873
    Abstract: A method for supervising a process for producing a metal alloy object with a known chemical composition. A resistivity of the metal alloy object is determined. A content of dissolved alloying elements in the metal alloy object is estimated based on the determined resistivity and the chemical composition of the metal alloy object. A content of precipitated alloying elements in the metal alloy object is estimated based on the determined resistivity and the chemical composition of the metal alloy object. The production process is supervised based on a ratio between the estimated content of dissolved alloying elements and the estimated content of precipitated alloying elements.
    Type: Application
    Filed: August 15, 2012
    Publication date: February 7, 2013
    Applicant: ABB AB
    Inventors: Sten Linder, Lennart Thegel
  • Patent number: 8370082
    Abstract: A method for predicting a physical property of a residue obtainable from a crude oil by a process of distillation, wherein the conditions during the process are represented by a processing parameter, is disclosed. The method includes the steps of: a) using a spectroscopic technique to acquire a spectrum for the crude oil; and b) applying a predictive model based upon a correlation between the spectrum, the physical property and the processing parameter. The method may be used to predict the suitability of crude oil for bitumen production.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: February 5, 2013
    Assignee: Shell Oil Company
    Inventors: Peter De Peinder, Fred Adrianus Johannes Singelenberg, Tom Visser, Bert Marc Weckhuysen
  • Publication number: 20130030719
    Abstract: Methods and systems for identifying a quantitation cycle (Cq) for a PCR reaction that includes fitting a line having a plurality of line segments to data points associated with a PCR amplification reaction. The data points include a cycle value associated with a PCR cycle and a product value associated with a PCR product. A baseline is identified and reaction segment associated with an exponential region of the PCR reaction is also identified. The reaction segment includes a subset of the plurality of line segments having a slope not less than a steepness criterion. A reaction line is fit to the data points associated with the reaction segment. The Cq is identified by calculating the cycle value for a data point defining the intersection of the baseline and reaction line.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: THERMO FISHER SCIENTIFIC OY
    Inventors: Jorma Mustola, Antti Koski
  • Patent number: 8364316
    Abstract: A method of modeling phase characteristics of thermodynamic systems utilizing pseudo-properties strategy and a reduced number of variables is disclosed herein. The method describes a means of determining the probability of phase splitting of mixtures of materials at a given temperature, pressure, and composition by characterizing the functions that describe the system via pseudo-properties, and also by describing the system in n?1 or fewer variables, where n represents the number of components in the system of interest. In an embodiment, a multi-component system is characterized in one variable, thereby providing simplified thermodynamic models in a time-efficient manner. In addition, the information generated by this reduced-variable calculation can further be used as a starting point for calculations of equations of state.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: January 29, 2013
    Assignee: Invensys Systems, Inc.
    Inventors: Gang Xu, David Bluck
  • Patent number: 8362415
    Abstract: A method of analyzing biological material by exposing the biological material to a recognition element, that is coupled to a mass tag element, directing an ion beam of a mass spectrometer to the biological material, interrogating at least one region of interest area from the biological material and producing data, and distributing the data in plots.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: January 29, 2013
    Assignees: Lawrence Livermore National Security, LLC, Lawrence Berkeley National Laboratory
    Inventors: James S. Felton, Kuang Jen J. Wu, Mark G. Knize, Kristen S. Kulp, Joe W. Gray
  • Patent number: 8364423
    Abstract: Chemical compositions in the blood may be selectively or preferentially excited by the application of scores comprising a series of at least four energy inputs to a blood vessel.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: January 29, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Muriel Y. Ishikawa, Edward K. Y. Jung, Nathan P. Myhrvold, Lowell L. Wood, Jr.
  • Patent number: 8357301
    Abstract: Herein is reported a method for determining whether a re-useable chromatography column packing, which is used at least for the second time in a purification step of a purification of a polypeptide, has reduced separation efficacy in said purification step of said purification of said polypeptide, comprising the following steps: a) identifying and determining the experimental data of an inert change of at least one physicochemical parameter of a mobile phase passing through said re-useable chromatography column packing, b) determining the parameters of a function of formula I by fitting the experimental data of the inert change of the physicochemical parameter of the at least second use, c) determining the difference between the experimental data of the inert change of the physicochemical parameter of the at least second use and the function of formula I with the parameters determined in step b), d) calculating the difference between the maximum value and the minimum value of the difference determined in step
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: January 22, 2013
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Anton Belousov, Thomas Dams, Benjamin Gerwat
  • Patent number: 8359168
    Abstract: The present invention relates to a fuel identification system and method normally applied to internal combustion engine vehicles of the flex-fuel type by means of which it is possible to identify the composition of the fuel used at each point in time, particularly the ratio used in a gasoline/ethanol blend or detect the presence of air or fuel in the vapor state in the fuel line, using the same device that heats the fuel.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: January 22, 2013
    Assignee: Robert Bosch Limitada
    Inventors: Fernando Lepsch, Marcos Melo Araujo, Hilton Rafael Spiler, Carlos Henrique De Oliveira Melo, Hans Hugo Eichel, Jr.
  • Publication number: 20130018599
    Abstract: A graphene nano-sensor with a suspended graphene flake electrically connected to metal electrodes. The graphene nano-sensor is capable of detecting single molecules in an atmosphere through a change in electrical conductance through the graphene flake.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 17, 2013
    Inventor: Haibing Peng
  • Publication number: 20130018593
    Abstract: Systems and methods are provided for analyzing data to determine properties of a PCR process or other process exhibiting amplification or growth. Data representing an amplification can be distinguished from data representing a jump or other error. A modified sigmoid function containing a drift term may be used in determining the properties. A multi-stage functional fit of the amplification data can provide increased accuracy and consistency of one or more of the properties. A baseline of the amplification data can be determined by analyzing an integrated area of a first derivative function of the data. A reference quantitation value can also be determined from locations of maxima of different derivative functions of the amplification data, e.g., a weighted average of the maxima locations for the second and third derivatives may be used.
    Type: Application
    Filed: September 24, 2012
    Publication date: January 17, 2013
    Applicant: Bio-Rad Laboratories, Inc.
    Inventor: Bio-Rad Laboratories, Inc.
  • Publication number: 20130009781
    Abstract: An Anti-Terrorism water quality monitoring system for continuously monitoring a potable water treatment system and related potable water distribution network that provides potable water to a municipality, city, housing development or other potable water consumer. The system includes the collection of data from the water distribution system and from the water treatment facility and from advanced separation processes which are integrated into analytical instruments. The data collected are stored in a remote database on a remote server computer or bank of computers and accessible by Homeland Security or its designated agency. Preferred parameters of monitoring include the turbidity and disinfectant such as chlorine, hypochlorous acid, sodium hypochlorite, calcium hypochloritc, ozone, chlorine dioxide, chloramines, hydrogen peroxide, peracetic acid.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Applicant: HACH COMPANY
    Inventor: Thomas D. Wolfe
  • Publication number: 20130013218
    Abstract: According to various embodiments, package evaluation systems and methods are provided for evaluating the sustainability of packaging used in the shipment of goods. In particular, the package evaluation systems and methods are configured for performing package evaluations and managing and providing access to data resulting from package evaluations. The package evaluations are designed to assess, among other things, the ability of sample packages to prevent damage to their contents, the volumetric efficiency of sample packages, and the sustainability of the materials used to construct sample packages. In addition, the systems and methods are further configured for assigning a certification to an entity associated with the evaluated packages based on the results of the evaluation.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Applicant: UNITED PARCEL SERVICE OF AMERICA, INC.
    Inventors: Arnold Barlow, Dennis R. Estep, Andrew J. Gruber, Patrick McDavid, Quinto Marini, Nancy Parmer
  • Publication number: 20130008149
    Abstract: Systems and methods for estimating an efficiency of a catalyst placed in an exhaust path of a combustion engine are disclosed. In one example approach, a method comprises: ageing the catalyst consecutively at different temperatures for definite time periods; measuring the catalyst conversion efficiency after each ageing step; calculating the ageing factor for each step of the ageing procedure and the accumulative value of the ageing factors for all steps of the ageing procedure; estimating catalyst efficiency correlation factors related to the measured catalyst conversion efficiency for each temperature point and for all ageing conditions; determining a correlation between the catalyst efficiency correlation factors and the accumulative value of the ageing factors; and calculating the conversion efficiency of the aged catalyst based on a predetermined correlation between the accumulative ageing factor and the catalyst efficiency correlation factor.
    Type: Application
    Filed: June 28, 2012
    Publication date: January 10, 2013
    Applicant: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Robert Ukropec, Alexey A. Dubkov, Yasser Mohamed Sayed Yacoub, Albert N. Chigapov, Nina Shishkina, Brendan Patrick Carberry
  • Patent number: RE44345
    Abstract: Apparatuses and methods providing data such as, for example, calibration and reagent information (30) over a network (6) to a measurement apparatus (4) which makes use of a consumable reagent (18) in a measuring process are disclosed. The present invention permits a measurement apparatus (4) to download the necessary code assignment (24) and calibration data (32) of the consumable reagent (18) by means of an electronic communication protocol from a host (33). The host (33) can be a software application running on a host computer (34), another measurement apparatus (50, 58) with or without a code-key slot used to read a memory device providing the above mentioned information (30), a dedicated connectivity device, such as a docking station (44), a portable memory reader (48), a remote computer (54), and combinations thereof.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: July 9, 2013
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventors: Friedrich Karl Ackermann, Manfred Augstein, Timothy L. Beck, Markus Stephan Fuerst, Robert Lawrence Meek, Philip Edgar Pash, Blaine Edward Ramey, Robert Paul Sabo, Matthew Carlyle Sauers, Joerg Schreiber, Wolfgang Walter, Seth Faulkner Williams, Frederick Leland Wittekind, III