With Detail Of Sampling, Sample Handling, Or Sample Preparation Patents (Class 73/61.59)
  • Publication number: 20110197662
    Abstract: Systems and methods for collecting portions of a target sample are disclosed herein. A method for detecting the presence and/or properties of a target sample can include selectively collecting a portion of a target sample with a sample collector and detecting, with the sample collector, the presence of one or more properties of the microscopic portion of the target sample. The method also includes analyzing, with the sample collector, the one or more properties of the microscopic portion of the target sample. Based on the analysis, the method further includes reporting, from the sample collector, a real-time indication of the analysis of the one or more properties of the target sample. The method can also include at least partially removing the microscopic portion of the target sample from the sample collector.
    Type: Application
    Filed: February 14, 2011
    Publication date: August 18, 2011
    Applicant: McAlister Technologies, LLC
    Inventor: Roy Edward McAlister
  • Patent number: 7992430
    Abstract: Methods and devices for measuring chemical or biological properties of a liquid from a subsurface position are disclosed, wherein a closed casing is submerged in the liquid to be sampled. The flow of the liquid for the sampling is driven by a hydrostatic pressure and is thus independent of pumps or the like when placed at the correct subsurface position. The flow rate is in a first aspect of the present invention controlled by providing a constant hydrostatic pressure during the sampling period. Alternatively, the inlet is provided with a cartridge comprising a tracer material, which is partly soluble by the liquid and is released proportional to the flow rate.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: August 9, 2011
    Assignee: Sorbisense Aps
    Inventor: Hubert de Jonge
  • Patent number: 7987701
    Abstract: Capillary membrane sampling-flow injection analyzer (CMS-FIA) analyses of drinking water samples for quantity measurements of total trihalomethane and haloacetic acid contaminants therein are provided. With the necessity to chlorinate drinking water to remove harmful bacteria and other potential toxins, trihalomethane and haloacetic acid byproducts are generated that may harm humans after consumption as well. A reliable manner of measuring such drinking water supplies for such trihalomethane and/or haloacetic acids at locations far from the source and closer to dispensers is highly desirable. The CMS-FIA analysis method of the invention has been found to be nearly as reliable as source measuring methods for the same purpose, but with the versatility to measure for such trihalomethane and haloacetic acid contaminants anywhere along the drinking water supply line.
    Type: Grant
    Filed: May 7, 2008
    Date of Patent: August 2, 2011
    Assignee: University of Memphis Research Foundation
    Inventors: Gary Lynn Emmert, Michael Andrew Brown, Gija Geme, Paul Steven Simone, Jr.
  • Publication number: 20110174064
    Abstract: A method of predicting formation of an amyloid plaque in a peptide sample is disclosed. The method comprises determining presence of quantum confinement in the sample, and predicting that formation of an amyloid plaque is likely to occur if the sample exhibits quantum confinement.
    Type: Application
    Filed: September 30, 2009
    Publication date: July 21, 2011
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Nadav Amdursky, Nadav Amdursky, Ehud Gazit, Gil Rosenman
  • Publication number: 20110162438
    Abstract: In a sample-processing system having function modules and buffer units each combined as a pair with one another, in case of device stoppage due to failure, since a number of sample racks are held in the buffers, resetting involves a huge amount of time for storage of the racks. In addition, if the system configuration includes a plurality of buffer units, the resetting time increases with the number of buffer units. Sample rack ID reading means is provided in each buffer unit and during resetting, IDs of the sample racks in the buffer unit are read in the buffer unit. The buffer unit then uses the read information to make an inquiry to a control unit as to transport destinations of each sample rack. After this, sample processing based on transport destination instructions from the control unit is restarted using the buffer unit as a restarting position.
    Type: Application
    Filed: August 28, 2009
    Publication date: July 7, 2011
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Hitoshi Tokieda, Yoshimitsu Takagi, Masashi Akutsu, Shotaro Sagawa
  • Publication number: 20110154889
    Abstract: Carrying cases for medical devices and components thereof are provided. Also provided are methods for carrying medical devices and for medical testing.
    Type: Application
    Filed: December 28, 2010
    Publication date: June 30, 2011
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Gary Ashley Stafford, Mark Kent Sloan, Johnny Chang, Jessica Ching, Mina Min Leung
  • Publication number: 20110146390
    Abstract: A micro-fluidic method for continuous pressure-driven flow injection analysis and a planar microfluidic device intended for pressure driven flow injection analysis are provided. A network of microchannels allows a continuous flow of sample stream on the devices, as well as facile and reproducible analyte plug injection to a reagent or buffer stream on microchip-based devices. The method allows for sequent separation analysis without additional purging cycles.
    Type: Application
    Filed: February 14, 2011
    Publication date: June 23, 2011
    Applicant: CRYSTAL VISION MICROSYSTEMS LLC
    Inventors: Scott E. Gilbert, Mario Schlund
  • Publication number: 20110151576
    Abstract: A method for the assessment of a multiphase (aqueous and organic) sample phase, the method comprising adding at least one detection molecule to the multiphase sample; detecting a signal emitted from the detection molecule/multiphase sample mixture, the signal being detectably different when the at least one detection molecule is present in one of either an organic phase, an aqueous phase or an interface between said organic phase and said aqueous phase of the multiphase sample; and analysing the detected signal to assess the properties of a phase or an interface between phases. A system for use in such a method, use of at least one detection molecule for the assessment of a multiphase sample, and a composition for use in the assessment of a multiphase sample are also disclosed.
    Type: Application
    Filed: July 20, 2009
    Publication date: June 23, 2011
    Applicant: LUX INNOVATE LIMITED
    Inventors: Emma Perfect, Catherine Rowley-Williams, Cameron Mackenzie, Artin Moussavi
  • Publication number: 20110146389
    Abstract: A continuous flow syringe pump includes a first syringe configured for at least one of loading or dispensing at least one fluid, a second syringe configured for at least one of loading or dispensing the at least one fluid, and a first valve connected to the first syringe and the second syringe. The continuous flow syringe pump also includes a second valve connected to the first valve. The continuous flow syringe pump further includes at least one outlet connected to the first valve. The at least one outlet is configured to alternate output of the at least one fluid between the first syringe and the second syringe in a substantially continuous operation.
    Type: Application
    Filed: December 21, 2009
    Publication date: June 23, 2011
    Inventor: Daniel R. Wiederin
  • Publication number: 20110126615
    Abstract: Provided is a method for analyzing a dispersion made by dispersing a liquid or solid dispersoid into a liquid dispersion medium. The method includes the steps of: preparing a sample liquid from the dispersion by forming an agglomerate of the dispersoid in the dispersion medium; redispersing the dispersoid that forms the agglomerate in the sample liquid into the dispersion medium of the sample liquid; and measuring the amount of the dispersoid that has been redispersed from the agglomerate in the sample liquid.
    Type: Application
    Filed: July 15, 2009
    Publication date: June 2, 2011
    Applicant: POKKA CORPORATION
    Inventors: Takashi Inoue, Joju Niida, Yasuki Matsumura, Kentaro Matsumiya
  • Patent number: 7930948
    Abstract: A apparatus and process for quantifying of contaminants, wherein the apparatus comprises a container that includes a housing to support a sample, and a gel elastomer inside the enclosure. The gel elastomer is capable of absorbing the contaminants that are leached from the sample. The gel may be a PDMS gel, and is preferable coated on a, or the side wall of the apparatus. After a period of time, the gel is analyzed for the presence and amount of contaminants.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: April 26, 2011
    Assignee: Vanderbilt University
    Inventors: Leslie M. Shor, Andrew Garrabrants, David S. Kosson
  • Patent number: 7921739
    Abstract: A method for in situ sampling and monitoring of a fluid flowing in a flow path, whereby the fluid is to be directed to a chamber a first valve may provide a connection between an inlet to the chamber and the flow path and a second valve may provide a connection between an outlet from the chamber and the flow path, comprising the following steps: a) opening the first valve and the second valve to let the incoming fluid flow through the inlet to the chamber and from the chamber through the outlet into the continuation of the fluid path, thereby allowing fluid to circulate through the chamber for a certain time, b) trapping the fluid in the chamber by closing the second valve and thereafter closing the first valve, c) opening a valve 9 for reducing pressure, to obtain a pressure in the chamber suitable for monitoring the fluid, d) opening an access valve 11 and leading the fluid trapped in the chamber into a monitor system wherein the fluid is analyzed, and thereby providing the data representing the fluid chara
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: April 12, 2011
    Inventors: Sølve J. Fjerdingstad, John F. Reintjes, John E. Tucker, Lawrence L. Tankersley
  • Publication number: 20100288028
    Abstract: Environmentally friendly solvents used to dissolve or remove residues and/or substances from substrates wherein the residue and/or substance is contacted with a Generally Recognized As Safe solvent to dissolve the residue and/or substance in the solvent followed by the extraction of the residue and/or substance from the solvent such as by contact with carbon dioxide.
    Type: Application
    Filed: July 27, 2010
    Publication date: November 18, 2010
    Inventors: Ruben G. Carbonell, Peter Kilpatrick, Nael Zaki
  • Publication number: 20100116026
    Abstract: A method of inspecting containers for contamination in a container filling plant, and an arrangement therefor. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.
    Type: Application
    Filed: May 13, 2009
    Publication date: May 13, 2010
    Inventor: Gyula VARHANIOVSZKI
  • Publication number: 20100107743
    Abstract: A device for determining an analyte in a sample of liquid comprises an analysis apparatus configured to analyze a sample of liquid applied to an analytical area of a test element. The device comprises further an apparatus configured to prepare a surface of the analytical area by conferring hydrophilic properties to the surface. Analytes in test samples are determined by methods employing the device.
    Type: Application
    Filed: September 16, 2009
    Publication date: May 6, 2010
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Holger Jabs, Norbert Ladiges, Herbert Fink
  • Publication number: 20100081213
    Abstract: Provided is a microfluidic apparatus including: a microfluidic structure for providing spaces for receiving a fluid and for forming channels, through which the fluid flows; and valves for controlling the flow of fluid through the channels in the microfluidic apparatus. The microfluidic structure includes: a sample chamber; a sample separation unit receiving the sample from the sample chamber and separating a supernatant from the sample by using a centrifugal force; a testing unit receiving the supernatant from the sample separation unit for detecting a specimen from the supernatant using an antigen-antibody reaction, and a quality control chamber for identifying reliability of the test.
    Type: Application
    Filed: September 29, 2009
    Publication date: April 1, 2010
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Beom Seok LEE, Ji Won KIM, Jeong Gun LEE, Kui Hyun KIM
  • Publication number: 20100058842
    Abstract: A self-propelled apparatus for analyzing a component contained in a fluid medium. The self-propelled apparatus uses kinetic energy of the apparatus to drive a fluid under analysis through the apparatus. This is accomplished by use of a conveyance system that is attached to the analytical system of the apparatus. A sensor system is used to analyze the component collected within the confines of an analysis chamber, a part of the analysis system. The invention also includes a method of using the analytical apparatus.
    Type: Application
    Filed: November 10, 2009
    Publication date: March 11, 2010
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: David P. Fries, Michelle L. Janowiak, George Steimle, Heather A. Broadbent
  • Publication number: 20100058843
    Abstract: A submersible, self-propelled apparatus for analyzing a component contained in a liquid medium. The submersible, self-propelled apparatus uses kinetic energy of the apparatus to drive a liquid under analysis through the apparatus. This is accomplished by use of a conveyance system that is attached to the analytical system of the apparatus. A sensor system is used to analyze the component collected within the confines of an analysis chamber, a part of the analysis system. The invention also includes a method of using the analytical apparatus.
    Type: Application
    Filed: November 10, 2009
    Publication date: March 11, 2010
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: David P. Fries, Michelle L. Janowiak, George Steimle, Heather A. Broadbent
  • Patent number: 7648836
    Abstract: Systems and methods for measuring the moisture and sediment content of a sample. In one embodiment, a sample to be tested is collected in a field bottle. The sample from the field bottle is then transferred from the field bottle, and into and through an analysis bottle containing a desiccant material. As the sample is being pulled through the analysis bottle, a microwave measurement system (or other scattering parameter measuring system) is used to measure the effects of the sample on the scattering parameters of the desiccant material. By measuring the effects of the sample on the scattering parameters of the desiccant material, the sample's moisture content can be determined. The sample's moisture can also be determined by measuring the expanded volume of the desiccant. A filter section having a sight glass with graduations is used to determine the sediment content of the sample.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: January 19, 2010
    Assignee: Phase Dynamics, Inc.
    Inventor: Bentley N. Scott
  • Publication number: 20090145206
    Abstract: A liquid gas vaporization and measurement system, and associated method, for efficiently vaporizing a continuous sample of liquid gas, such as liquid natural gas (LNG), and accurately determining the constituent components of the gas. A constant flow of liquid gas sampled from a mass storage device is maintained in a vaporizing device. Within the vaporizing device the liquid gas is flash vaporized within heated narrow tubing. The liquid gas is converted to vapor very quickly as it enters one or more independently operating vaporizer stages within the vaporizing device. The vapor gas is provided to a measuring instrument such as a chromatograph and the individual constituent components and the BTU value of the gas are determined to an accuracy of within +/?0.5 mole percent and 1 BTU, respectively.
    Type: Application
    Filed: January 30, 2009
    Publication date: June 11, 2009
    Applicant: Mustang Sampling LLC
    Inventors: Kenneth O. Thompson, Walter F. Gerhold
  • Publication number: 20090127181
    Abstract: A treatment tank for treating waste water or other liquid is provided. The treatment tank has an interior cavity of the treatment tank, a liquid introduction system for introducing a liquid to be treated, into a top end of the treatment tank, an exit aperture for removing liquid from a bottom end of the treatment tank and a plurality of removable layers of filter media. The removable layers of filter media are spaced substantially vertically in the treatment tank between the top end of the treatment tank and the bottom end of the treatment tank. Each layer of filter media has a permeable sheet adjacent a bottom surface of the layer of filter media, the permeable sheet allowing liquid to pass through the permeable sheet but preventing filter media in the layer of filter media from passing through the permeable sheet.
    Type: Application
    Filed: November 15, 2007
    Publication date: May 21, 2009
    Inventor: Udo Staschik
  • Publication number: 20090120170
    Abstract: Environmentally friendly solvents used to dissolve or remove residues and/or substances from substrates wherein the residue and/or substance is contacted with a Generally Recognized As Safe solvent to dissolve the residue and/or substance in the solvent followed by the extraction of the residue and/or substance from the solvent such as by contact with carbon dioxide.
    Type: Application
    Filed: December 16, 2008
    Publication date: May 14, 2009
    Inventors: Ruben G. Carbonell, Peter Kilpatrick, Nael Zaki
  • Patent number: 7493800
    Abstract: A method for sampling a host liquid in a vessel to detect the presence of an undesired liquid in the host liquid and removing host liquid that contains undesired liquid from the vessel, wherein an electrical capacitance probe is employed to detect the presence of the undesired liquid, and the liquid that is passed by the capacitance probe is fed to an incinerator.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: February 24, 2009
    Assignee: Equistar Chemicals, LP
    Inventors: Ahmad Zamanian, Lawrence W. Dvorak, Brian K. Reed
  • Patent number: 7484404
    Abstract: A liquid gas vaporization and measurement system, and associated method, for efficiently vaporizing a continuous sample of liquid gas, such as liquid natural gas (LNG), and accurately determining the constituent components of the gas. A constant flow of liquid gas sampled from a mass storage device is maintained in a vaporizing device. Within the vaporizing device the liquid gas is flash vaporized within heated narrow tubing. The liquid gas is converted to vapor very quickly as it enters one or more independently operating vaporizer stages within the vaporizing device. The vapor gas is provided to a measuring instrument such as a chromatograph and the individual constituent components and the BTU value of the gas are determined to an accuracy of within +/?0.5 mole percent and 1 BTU, respectively.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: February 3, 2009
    Assignee: Mustang Sampling LLC
    Inventors: Kenneth O. Thompson, Walter F. Grehold
  • Publication number: 20090000359
    Abstract: A method for sampling a host liquid in a vessel to detect the presence of an undesired liquid in the host liquid and removing host liquid that contains undesired liquid from the vessel, wherein an electrical capacitance probe is employed to detect the presence of the undesired liquid, and the liquid that is passed by the capacitance probe is fed to an incinerator.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 1, 2009
    Inventors: Ahmad Zamanian, Lawrence W. Dvorak, Brian K. Reed
  • Publication number: 20080245134
    Abstract: A method of monitoring a surfactant in a microelectronic process is disclosed. Specifically, the monitoring of a surfactant occurs by studying the absorbance of a sample collected from a microelectronic process.
    Type: Application
    Filed: April 5, 2007
    Publication date: October 9, 2008
    Inventors: Amy M. Tseng, John E. Hoots, Brian V. Jenkins
  • Publication number: 20080236257
    Abstract: Methods and devices for measuring chemical or biological properties of a liquid from a subsurface position are disclosed, wherein a closed casing is submerged in the liquid to be sampled. The flow of the liquid for the sampling is driven by a hydrostatic pressure and is thus independent of pumps or the like when placed at the correct subsurface position. The flow rate is in a first aspect of the present invention controlled by providing a constant hydrostatic pressure during the sampling period. Alternatively, the inlet is provided with a cartridge comprising a tracer material, which is partly soluble by the liquid and is released proportional to the flow rate.
    Type: Application
    Filed: September 28, 2005
    Publication date: October 2, 2008
    Applicant: SORBISENSE APS
    Inventor: Hubert de Jonge
  • Patent number: 7407625
    Abstract: Systems and methods for measuring the moisture and sediment content of a petroleum sample. In one embodiment, a sample to be tested is collected in a field bottle. The sample from the field bottle is then transferred from the field bottle, and into and through a measurement column containing a high-uptake gelling agent, such as a superabsorbent polymer. The sample's moisture is determined by measuring the expanded volume of the high-uptake gelling agent. The measurement column also contains a sediment measurement section having a sediment filter and a sight glass with graduations to measure the sediment content of the sample.
    Type: Grant
    Filed: April 14, 2005
    Date of Patent: August 5, 2008
    Assignee: Phase Dynamics, Inc.
    Inventor: Bentley N. Scott
  • Patent number: 7393508
    Abstract: The valve arrangement comprises a predetermined number of individual valve functionalities, arranged in a manner parallel to each other. A fixed connector plate (3) has a number of sample funnel tubes (6) and output connections (8) for forward transfer of the samples arranged offset from the above. A valve plate (14) with the same number of sample loops (24) for accommodating precisely measured sample amounts may be displaced linearly with respect to the connector plate. In a first position the sample loops are connected to the sample funnel tubes and in a second position with the output connections.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: July 1, 2008
    Inventors: Hansjörg Emil Cueni, Heiner Scherrer
  • Publication number: 20080090256
    Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.
    Type: Application
    Filed: October 13, 2006
    Publication date: April 17, 2008
    Inventors: Ian Gibbons, Michael O'Connell
  • Patent number: 7354768
    Abstract: Systems and methods for measuring the moisture and sediment content of a petroleum sample. In one embodiment, a sample to be tested is collected in a field bottle. The sample from the field bottle is then transferred from the field bottle, and into and through a measurement column containing a high-uptake gelling agent, such as a superabsorbent polymer. The sample's moisture is determined by measuring the expanded volume of the high-uptake gelling agent. The measurement column also contains a sediment measurement section having a sediment filter and a sight glass with graduations to measure the sediment content of the sample.
    Type: Grant
    Filed: April 14, 2005
    Date of Patent: April 8, 2008
    Assignee: Phase Dynamics, Inc.
    Inventor: Bentley N. Scott
  • Patent number: 7304588
    Abstract: An apparatus for monitoring an article or system, particularly an LP or propane tank, includes a transmission unit, a base unit and a host unit. The transmission unit is disposed on or near the article or system and detects at least one parameter related to the article or system and send information related to the detected parameter. The base unit is disposed at a predetermined location remote from the article or system. The base unit receives information related to the detected parameter from the transmission unit. The host unit is disposed at a location remote from the base unit and the transmission unit. The host unit receives information related to the detected parameter from the base unit for management purposes. A method of monitoring an article or system such as a fuel tank is also disclosed.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: December 4, 2007
    Assignee: Independent Technologies, Inc.
    Inventors: Daryl Ingalsbe, Greg Molenaar, Jim Fangmeier, Luke Smith, Jonathan Meed, Douglas H. Ferguson, Tim Siegfried
  • Patent number: 7157056
    Abstract: A sample introduction device is provided that is particularly useful in the critical care environment for the anaerobic withdrawal of small volumes of arterial blood from a sample collection syringe and introduction thereof into a sample chamber of a sensor for analysis. The sample introduction device includes a Luer fitting adapted to mate an outlet of the container in a concentric orientation with an input aperture of the sample chamber. A tubular probe is adapted for concentric placement with both the outlet and inlet aperture, with a first end thereof extending into the syringe and a second end adapted for attachment to an air supply. The probe has a predetermined diameter sufficient to provide an annular clearance between the probe and each of the outlet and inlet aperture. A predetermined volume of air is injected through the probe into the container to displace a predetermined volume of sample therefrom, through the annular clearance into the sample chamber.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: January 2, 2007
    Assignee: Bayer Corporation
    Inventor: Kevin J. Sullivan
  • Patent number: 7066011
    Abstract: The present invention aims to provide a liquid chromatograph, an analysis system, and a gradient elution method, which are designed to permit a gradient change of eluent with higher precision and also permit a high sensitive detection or analysis.
    Type: Grant
    Filed: April 8, 2001
    Date of Patent: June 27, 2006
    Assignee: Nano Solution, Inc.
    Inventors: Yoshi Yamauchi, Tohru Natsume, Toshiaki Isobe
  • Patent number: 6860142
    Abstract: An automatic system for monitoring/controlling a variable of a machine or metalworking fluid system also achieves cleaning and optionally, a calibration check of the sensor of the variable. The system includes one or more sensors for variables such as pH, fluid concentration, conductivity, temperature and the like, a supply of a cleaning agent and associated valves and conduits for connecting the automatic system to a fluid to be measured. A cleaning cycle can be scheduled as necessary to clean and/or check calibration of the sensors and ensure accurate measurement of sensed variables. If desired, the data regarding the sensed variables may be utilized to perform corrective action in real time.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: March 1, 2005
    Assignee: Master Chemical Corporation
    Inventors: Stanley W. Seevers, Guy R. Hughes, Frank A. Robinson
  • Patent number: 6823721
    Abstract: A system which receives as inputs various measurements of solids and liquids in a clarification system and, from these measurements, determines the various constituents and their fractional makeup within the system. The measurements may be made manually or mechanically, but are preferably made manually. From a quantitative analysis of easily accessible sample points, data is acquired and plugged into a spread sheet program, which numerically and graphically displays the breakdown of the constituents which make up the solids and liquids discharged from a treatment stage or of the entire system.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: November 30, 2004
    Assignee: Hutchison Hayes, L.P.
    Inventors: Lee Hilpert, Gary L. Hensley
  • Publication number: 20040159145
    Abstract: An automatic system for monitoring/controlling a variable of a machine or metalworking fluid system also achieves cleaning and optionally, a calibration check of the sensor of the variable. The system includes one or more sensors for variables such as pH, fluid concentration, conductivity, temperature and the like, a supply of a cleaning agent and associated valves and conduits for connecting the automatic system to a fluid to be measured. A cleaning cycle can be scheduled as necessary to clean and/or check calibration of the sensors and ensure accurate measurement of sensed variables. If desired, the data regarding the sensed variables may be utilized to perform corrective action in real time.
    Type: Application
    Filed: February 14, 2003
    Publication date: August 19, 2004
    Inventors: Stanley W. Seevers, Guy R. Hughes, Frank A. Robinson
  • Patent number: 6770876
    Abstract: The present invention relates to an autosampler device useful in high pressure liquid chromatography (HPLC), and more particularly to a device useful for the automated introduction of small sample volumes into a HPLC system. Methods of analyzing low abundant protein samples using such a device are also included.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: August 3, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ming Gu, Wenjeng Li, John W. Allen
  • Patent number: 6758964
    Abstract: A device for separating and renewing phases of a diphasic liquid—liquid mixture, in which a first liquid phase and a second liquid phase are circulated in counter current in a liquid—liquid extraction device. The device is in the form of a straight hollow cylinder with one of the bases being either the wall of the device or being in contact with the wall of the device. The device also includes an input orifice for the phase the user wishes to trap, an output orifice that is smaller than the input orifice for the phase that the user wishes to trap, separated, and a third orifice of an intermediate size when compared to the size of the input and output orifices for evacuating a non-desired phase.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: July 6, 2004
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Danielle Roudil, Francis Malzieu
  • Patent number: 6746863
    Abstract: An improved tube probe for measuring volatile compounds in a liquid or gas contained in a reactor or in any other environment is disclosed. The probe is made of a single piece of metal, to one end of which is attached a gas permeable tubing, threaded on a supporting plate. The plate permits to use of a variety of tube lengths and diameters while protecting the tube from mechanical stress due to agitation and aeration. Furthermore, the plate gives the possibility to have a longer permeable tube than the single loop probe approach. The probe is designed so that when in use, substantially only the tube is located inside the reactor. The volatile compounds permeate into the tube into the carrier gas and the carrier gas+volatiles mixture is carried to a detector through a channel provided in the probe body. The probe is economical to make and to maintain, while achieving high performance.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: June 8, 2004
    Assignee: National Research Council of Canada
    Inventor: Mario Béland
  • Patent number: 6737022
    Abstract: A system for separating an aqueous stream of mixed polynucleotides into a series of length-based polynucleotide fractions and collecting one or more of the length-based polynucleotide fractions into separate containers. The system comprises a separation column containing separation media for separating an aqueous stream of mixed polynucleotides into a series of length-based polynucleotide fractions; a container including one or more single-sample containers; an ejection chamber having a separated sample inlet for receiving the length-based polynucleotide fractions, a waste outlet for discharging uncollected sample, and a capillary-sized fraction outlet positioned to discharge a selected length-based polynucleotide fraction into a single-sample container. The system also includes means for effecting discharge of a selected length-based polynucleotide fraction into the separate container.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: May 18, 2004
    Assignee: Transgenomic, Inc.
    Inventors: John E. Sutton, Donn H. Vanden Bosch
  • Publication number: 20030197125
    Abstract: Apparatus and method for in situ measurements of at least one property of a liquid contained within a vessel.
    Type: Application
    Filed: April 19, 2002
    Publication date: October 23, 2003
    Inventors: Robert De Saro, Arel Weisberg
  • Publication number: 20030119201
    Abstract: A method for determining substrate and product concentration in liquid and/or gaseous media is disclosed. Several samples of at least one substance to be analyzed are removed in at least one sampling region by time-controlled diffusion of the analyte between the medium and a diffusion medium, which is fed to the sampling regions through fluid conduits using at least one pump and semipermeable membranes. The diffusion medium is transported to at least one detector while simultaneously new diffusion medium is fed from the sampling region, and analyzed to determine the analyte concentration. The detector provides a temporal concentration distribution or a temporal distribution of a signal proportional to the concentration. A change in the ratio of the signal maximum to the base line is ascertained in the output of the detector signal and, on the basis of this, a change in the diffusion properties of the semipermeable membrane is inferred and a correction factor ascertained.
    Type: Application
    Filed: November 22, 2002
    Publication date: June 26, 2003
    Inventors: Evelyn Wolfram, Matthias Arnold, Andreas Franz, Dirk Weuster-Botz, Christian Wandrey
  • Patent number: 6541272
    Abstract: An apparatus and method for separating and analyzing a component of a fluid sample that is considered to be a contaminant, and particularly, that is or may be an organic material. The invention is predicated on the introduction of the sample fluid in a pulsed manner via a first carrier fluid into a feed chamber. A membrane is located between the feed chamber and an exit chamber, and in fluid registry therewith. When the sample enters the feed chamber, the component to be separated and analyzed can permeate the membrane, and thus passes through the membrane to the exit chamber, and then enters a second carrier fluid which carries it to a detector for analysis. The detector may be a gas chromatograph (GC), mass spectrometer (MS) or the like.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: April 1, 2003
    Assignee: New Jersey Institute of Technology
    Inventor: Somenath Mitra
  • Patent number: 6498040
    Abstract: A high-performance liquid chromatography apparatus and a process for conversion of mobile phase, enabling a trace amount of sample for NMR analysis to be efficiently separated and prepared, includes steps of separating a target ingredient from the sample by the high-performance liquid chromatography, trapping the target ingredient in a trapping column using a different mobile phase, replacing water by deuterium oxide and eluting this target ingredient from the trapping column using deuterated solvent other than deuterium oxide.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: December 24, 2002
    Assignee: Eisai Co., Ltd.
    Inventors: Yumi Yokoyama, Naoya Kishi, Masayuki Tanaka, Naoki Asakawa
  • Patent number: 6467340
    Abstract: The present invention provides a system that monitors and controls the precipitation of asphaltenes in a formation fluid recovered from a subsurface formation or reservoir by using a sensor to make a direct real-time on-site measurement of the relative concentration asphaltenes from at least one location at a wellsite or in a pipeline. In a system including a fiber optic attenuated total reflectance probe for sensing asphaltenes and using a processor to compare sequential measurements, the system of the present invention can trigger the addition of additives in response to a change in asphaltene concentration in the formation fluid, preventing precipitation.
    Type: Grant
    Filed: October 17, 2000
    Date of Patent: October 22, 2002
    Assignee: Baker Hughes Incorporated
    Inventors: Christopher Gallagher, C. Mitch Means
  • Patent number: 6420185
    Abstract: An apparatus and methods of utilizing a semi-permeable membrane to concentrate contaminants in a portion of an Ultra Pure Water stream to levels which are detectable by an on-line analyzer. This allows the use of analyzers that would not be able to accurately detect contaminant concentrations in the Ultra Pure Water stream. Thus, by knowing the concentration factor and the level of contaminants in the concentrated stream indicated by the analyzer the real level of contamination can be back calculated.
    Type: Grant
    Filed: September 28, 1999
    Date of Patent: July 16, 2002
    Assignee: Intel Corporation
    Inventor: Gregory E. Carr
  • Patent number: 6260407
    Abstract: Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems and methods, including liquid chromatography and flow-injection analysis systems and methods are preferably employed. High throughput, automated sampling systems and methods, high-temperature characterization systems and methods, and rapid, indirect calibration compositions and methods are also disclosed. In preferred high-temperature embodiments, the polymer sample is maintained at a temperature of not less than about 75° C. during sample preparation, loading into a liquid chromatography or flow-injection analysis system, injection into a mobile phase of a liquid chromatography or flow-injection analysis system, and/or elution from chromatographic column. The described methods, systems, and device have primary applications in combinatorial polymer research and in industrial process control.
    Type: Grant
    Filed: April 2, 1999
    Date of Patent: July 17, 2001
    Assignee: Symyx Technologies, Inc.
    Inventors: Miroslav Petro, Adam Safir, Ralph B. Nielsen, G. Cameron Dales, Eric D. Carlson, Thomas S. Lee
  • Patent number: 6257052
    Abstract: The disclosed syringe pump and valve assembly utilizes a cylindrical housing having a piston axially moved therein for defining a pump chamber, where the housing is mounted to rotate about its longitudinal axis. A port seat is disposed concentrically of this axis spaced from one housing end, and a seal/valving member has one face seated slidably on the port seat and has its opposite face exposed to the pump chamber. Connectors serve to communicate separate liquid lines to separate respective ports on the port seat, which the seal/valving member first face overlies. The seal/valving member has through opening and/or radial or arcuate channels operable in different rotational member positions to selectively isolate or communicate the lines relative to one another and/or the pump chamber. The seal/valving member is designed to rotate in unison with the housing, and mechanism rotates the housing to locate the seal/valving member as required.
    Type: Grant
    Filed: July 6, 1999
    Date of Patent: July 10, 2001
    Assignee: Digichrom, Inc
    Inventor: Yury Zelechonok