Sample Holder Patents (Class 73/864.91)
  • Patent number: 7051606
    Abstract: The present invention comprises a device and methods for dissolution or immersion testing and, in particular, a device and methods that improve the consistency of test results by limiting the ability of pharmaceutical or other dosage forms to move or reorient during testing.
    Type: Grant
    Filed: January 30, 2004
    Date of Patent: May 30, 2006
    Assignee: Andrx Labs LLC
    Inventors: Dacheng Tian, Xiu Xiu Cheng, Jack Cardinal, Boyong Li, Avinash Nangia
  • Patent number: 6988394
    Abstract: A portable automated biomonitoring system for monitoring water quality includes an exposure chamber for housing an aquatic organism and a water inlet for directing water to the exposure chamber. The aquatic organism has ventilatory behavior and body movement sensitive to water quality. Electrodes sense electrical signals produced by the organism during its ventilatory behavior and body movement, and a controller responsive to signals from the electrodes determines a plurality of ventilatory parameters based on the signals. The ventilatory parameters are compared with corresponding thresholds to determine when the water to which the organism is exposed has caused physiological stress to the organism. The water being evaluated may be recirculated through the system for further analysis.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: January 24, 2006
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Tommy R. Shedd, Mark W. Widder, Mark W. Brown, Murray S. Swanson
  • Patent number: 6979033
    Abstract: An upper imperforate cap closes the uppermost end of a bailer and a lower imperforate cap closes the lowermost end of the bailer. In a preferred embodiment, screwthreads are formed in the uppermost and lowermost ends of the bailer and complemental screwthreads are formed in the upper and lower caps. By capping the opposite ends of a bailer, the bailer serves as its own container when the sample contained within it is shipped to a laboratory. This eliminates VOC devices, nozzles, and the concomitant contamination that may result from emptying a bailer in the field.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: December 27, 2005
    Inventor: David W. Pratt
  • Patent number: 6860632
    Abstract: A housing for a material holder includes an intermediate housing member having a generally horizontal member, an upper recess and a lower recess, an upper housing member having a generally horizontal member and a wall defining a material holding chamber, the upper housing member being seated within the upper recess of the intermediate housing member, and a lower housing member having a generally horizontal member, the lower housing member being seated within the lower recess of the intermediate housing member. The upper recess, the generally horizontal member of the intermediate housing member and the generally horizontal member of the upper housing member define a first cavity adapted to receive a first winding assembly, and the lower recess, the generally horizontal member of the intermediate housing member and the generally horizontal member of the lower housing member define a second cavity adapted to receive a second winding assembly.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: March 1, 2005
    Assignee: PerkinElmer Instruments LLC
    Inventor: Donald L. Groeschner
  • Patent number: 6857309
    Abstract: A library of materials is screened for mechanical properties such as surface tension or interfacial tension. A library of materials is provided. A stimulus such as a stress or force is provided to each member of the library. A response (e.g., a resistance) of each of the materials due to the stimulus is measured and the response, the stimulus or both are recorded and related to provide data. Thereafter, the data is analyzed to reach conclusions regarding the material samples.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: February 22, 2005
    Assignee: Symyx Technologies, Inc.
    Inventor: Paul Mansky
  • Patent number: 6846028
    Abstract: An upper imperforate cap closes the uppermost end of a bailer and a lower imperforate cap closes the lowermost end of the bailer. In a preferred embodiment, screwthreads are formed in the uppermost and lowermost ends of the bailer and complemental screwthreads are formed in the upper and lower caps. In another embodiment, screwthreads are formed in a downspout and complemental screwthreads are formed in an imperforate downspout cap. By capping the opposite ends of a bailer, the bailer serves as its own container when the sample contained within it is shipped to a laboratory. This eliminates VOC devices, nozzles, and the concomitant contamination that may result from emptying a bailer in the field.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: January 25, 2005
    Inventor: David W. Pratt
  • Patent number: 6844545
    Abstract: A sample plate structure is provided including a retainer plate having a central opening, a sample insert plate which fits into the opening, an optional pressure plate and a handle. The handle applies pressure to the sample insert plate to retain it within the retainer plate. The sample insert plate is provided with a peripheral configuration, which assures that the sample insert plate is properly oriented within the sample plate support structure and is held flat. While the sample insert plate can be a consumable, the remaining portion of the apparatus can be reused.
    Type: Grant
    Filed: October 10, 2003
    Date of Patent: January 18, 2005
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Timothy E. Hutchins, Andrew J. Tomlinson, Philip J. Savickas
  • Patent number: 6826949
    Abstract: A liquid sample sensing device comprises a set of stackable liquid sample base units that are adapted to be stacked together to form multiple sample volumes that are substantially sealed, each with an electroacoustic member disposed therein having a surface adapted for binding to a particular target molecule. Top and bottom units are preferably attached to a closed loop of flexible tubing and a peristaltic pump. Individual electroacoustic members in the stack can each be adapted to bind with different target molecules, allowing for a multiple target assay. Alternately, a plurality of electroacoustic members can be adapted to bind with the same type of target molecule, thereby increasing the sensitivity of the sensing device. The base units are adapted such that sample liquid is caused to flow over and be in close proximity to the sensing surface of each electroacoustic member as the sample liquid flows from one base unit to the next, thereby increasing the efficiency of binding.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: December 7, 2004
    Assignee: Becton, Dickinson and Company
    Inventor: Klaus W. Berndt
  • Publication number: 20040237670
    Abstract: A sample holder and auxiliary apparatus are provided to position and hold a sample in the sample holder. A method of positioning and holding a sample in the sample holder is also provided. The sample holder preferably includes a holder body having a sample holding portion arranged therein. An opening in the sample holding portion is configured to receive a sample therein. An elastic member is configured to supply a holding force to hold the sample in the opening. The auxiliary apparatus preferably includes one or more holder supports configured to support a sample holder. The auxiliary apparatus is configured to receive the sample holder and force a sample holding member of the sample holder into a rearward position to permit the sample holder to receive a sample into an opening thereof.
    Type: Application
    Filed: July 13, 2004
    Publication date: December 2, 2004
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Bon-Se Koo, Ho-Hyung Jung, Dae-Jung Kim
  • Patent number: 6825478
    Abstract: A sample plate structure is provided including a retainer plate having a central recess with a trough along its periphery, a sample insert plate which fits into and rests on contact surface of the recess, and a magnet that is held below the contact surface. A portion of the bottom surface of the insert is formed of a magnetic material. The magnet provides sufficient force to retain the insert plate in the retainer plate during MALDI MS analysis. The sample insert plate is provided with a peripheral configuration, which assures that the sample insert plate is properly oriented within the sample plate support structure and is held flat. A hole for a protrusion allows easy insert installation and alignment against the orientation feature in the recess as well as easy removal of the insert simply by pushing up from underneath the retainer plate. While the insert sample plate can be a consumable, the remaining portion of the apparatus can be reused.
    Type: Grant
    Filed: October 10, 2003
    Date of Patent: November 30, 2004
    Assignee: PerSeptive BioSystems, Inc.
    Inventors: Robert D. McCarthy, Kevin M. Hayden, Timothy E. Hutchins, Philip J. Savickas, Peter C. Cranshaw
  • Patent number: 6820508
    Abstract: An apparatus rotates a sample to facilitate an accurate analysis of the sample. The apparatus includes a sample stage on which a plurality of samples are supported, a rotatable cap and a linearly movable plate for placing a selected one of the samples at an analysis position, and a rotating stage that supports the sample stage, rotatable cap and movable plate. The rotating stage is rotatable about an axis of rotation that intersects the analysis position. Once the selected sample is placed at the analysis position by the rotation of the cap and the linear movement of the plate, the selected sample is rotated by the rotating stage. The analysis process can be selectively or sequentially carried out with respect to the plurality of samples with a high degree of efficiency and without the associated drive mechanisms experiencing high loads.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: November 23, 2004
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Sang-Eun Lee
  • Patent number: 6814936
    Abstract: A pipette assembly (10) having a suction device (12 or 52) and a small volume disposable tip (14) having a capacity with a range of 0.1 &mgr;l to 2.0 &mgr;l, the disposable tip being removably secured to the suction device. The suction device is provided with a female tip receiver (38.2 or 78.1) which receives a disposable male tip (14). The tip is in the form of a short piece of extruded tubing. The tubing has a very small i.d., for example 0.3 mm. It is preferably formed of Teflon®, or another hydrophobic material.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: November 9, 2004
    Inventor: Goran Enhorning
  • Patent number: 6772651
    Abstract: A soil sampler liner with areas of reduced wall thickness is defined by a continuous wall that has a reduced area extending along at least a portion of the length of the liner. The liner is inserted into the inner bore of a sampler probe, and a soil sample is taken by vertically inserting the probe and liner into the ground. The wall of the liner has at least two distinct areas of varying thickness; a reduced wall area and wall areas adjacent to the reduced wall area. The walls are sufficiently strong to withstand the forces applied to the liner when taking relatively large-diameter soil samples. The thickness of the wall at the reduced wall area is less than the thickness of the wall at the adjacent areas to permit a user to easily and safely cut through the wall at the reduced wall area and remove a large-diameter soil sample from the liner. The liner is also radially compressible into a flattened shape for compact and economical packaging and shipment of liners in relatively large quantities.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: August 10, 2004
    Assignee: Kejr, Inc.
    Inventors: Gregory H. Scott, Thomas M. Christy, Michael E. Carlin
  • Patent number: 6769317
    Abstract: A core sampling apparatus is comprised of a tubular punch, a storage container, and a press. The punch is comprised of a plurality of generally parallel metal sample tubes for being forced into a ground material. The storage container is comprised of a plurality of parallel storage tubes, a cap, and a lock nut. The filled punch is pushed into the storage tubes for encapsulation, and cap is secured against the open end of the storage container by the lock nut. The material samples are ejected from the storage container with an extraction tool with prongs attached to the press. Prongs on the extraction tool are inserted into the punch through breakable ends of the storage tubes, and the material samples are pushed out through breakable ends of the cap by the prongs into a collection vial.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: August 3, 2004
    Inventors: Edward M. Hamilton, Jindrich Dokonal
  • Publication number: 20040124193
    Abstract: An apparatus for the storage of cellular fluids. The apparatus comprises a first chamber capable of containing a sample of cellular fluid, and a second container which is adapted to receive fluid from the first container. The second container also comprises a bored piston which, when inserted into the first chamber, forces the cellular fluid through the bore and into the second chamber. As the first and second containers are brought together, the piston and the first chamber seal together to create a sealed volume. Also, as the cellular fluid is pressurised through the bored piston into the second chamber the cells of the fluid burst, leaving a disrupted sample which is safe from contamination or degradation.
    Type: Application
    Filed: December 4, 2003
    Publication date: July 1, 2004
    Inventor: Charles Buchan Ritchie
  • Publication number: 20040113072
    Abstract: A method for applying a sample film to a sample carrier for subsequent spectroscopic analysis is described, comprising providing a quantity of sample in liquid state, providing a sample carrier having at least one sample position, applying the quantity of sample in liquid state on the at least one sample position in a plurality of partial quantities of the quantity of sample in such a manner that the partial quantities on the at least one sample position are not in contact with one another before being dried, drying the quantity of sample to form the sample film.
    Type: Application
    Filed: September 30, 2003
    Publication date: June 17, 2004
    Applicant: Bruker Optik GmbH
    Inventor: Matthias Boese
  • Publication number: 20040074320
    Abstract: A specimen container chuck apparatus includes an open/close driver and a pair of holding members which are provided to hold a specimen container from an outer surface thereof. Each of the holding members is formed by bending a linear member having elasticity and includes a pair of support sections which extend in parallel along the outer surface of the specimen container, one end of each of the support sections being coupled to the open/close driver, a pair of container contact sections which are connected at one end to the support sections, respectively and bent and biased toward the outer surface of the specimen container, and a coupling section which couples the other ends of the container contact sections and are curved so as to surround the outer surface of the specimen container with a given gap therebetween.
    Type: Application
    Filed: August 29, 2003
    Publication date: April 22, 2004
    Inventor: Teruaki Itoh
  • Publication number: 20040069076
    Abstract: A sample processing device [700] comprises an elongated body [101] with a septum seal [109] on one end and a drip tube [731] on the second end. A small-diameter through-chamber [103] in the body provides a receiving and alignment chamber for a hypodermic needle [109] inserted into the septum. A sample processing chamber [709] provides a location for processing elements such as filters and adsorption or absorption frits [135,137]. Sample fluid injected into, or withdrawn from, the device by the hypodermic needle communicates with a bottom opening [701] of the drip tube via a drip tube nozzle [705], the sample processing chamber and the small-diameter chamber. The device is particularly useful in automated testing where the device is moved to various processing locations by the hypodermic needle.
    Type: Application
    Filed: October 7, 2003
    Publication date: April 15, 2004
    Inventor: Kimberly R. Gamble
  • Patent number: 6717156
    Abstract: There are disclosed a method for fabricating (processing) a micro-sample used for the observation, analysis, and measurement by, for example, a transmission electron microscope (TEM), and an equipment for specimen fabrication (processing) used for carrying out the method. With the method for specimen fabrication (processing) of the present invention, a micro-sample to be separated and extracted from a specimen substrate is sandwiched and held between a plurality of branch beams formed at the tip of a beam. The beam holding the micro-sample is transferred onto a sample holder, and the micro-sample is mounted (firmly held) on the sample holder. After mounting the micro-sample on the sample holder, the beam is detached and separated from the mounted micro-sample. By adopting such a method, it is possible to fabricate a specimen for high reliability observation, analysis, and measurement entailing less contamination, in a shorter time and with efficiency.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: April 6, 2004
    Assignee: Hitachi, Ltd.
    Inventors: Masakazu Sugaya, Hiroyasu Shichi, Muneyuki Fukuda, Kaoru Umemura, Hidemi Koike
  • Patent number: 6712161
    Abstract: A containment cartridge for extracting and preserving a soil sample comprises a cylindrical sampling barrel for insertion into the soil for collecting a soil sample.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: March 30, 2004
    Assignee: GD Air Testing, Inc.
    Inventor: Gesheng Dai
  • Publication number: 20040025603
    Abstract: A fluid collection apparatus is provided including an insert configured for disposal within a tube. The insert includes a first diameter, a second diameter and defines a chamber therebetween. The chamber extends from a closed end to an open end that is configured for receipt of a fluid sample. The second diameter may define an interior cavity of the insert. The interior cavity may include a base portion and a barrel portion. A method for collecting sediment from a fluid sample is disclosed.
    Type: Application
    Filed: November 8, 2002
    Publication date: February 12, 2004
    Inventors: John Liseo, Richard H. Hawley, Todd DeMatteo
  • Publication number: 20040025935
    Abstract: A fluid collection apparatus is provided including a tube defining a longitudinal axis and extending therealong from a closed end to an open end. The tube further defines an inner surface. An insert is configured for disposal within the tube and recessed from the open end. The insert includes a first diameter configured and dimensioned for engagement with the inner surface of the tube and a second diameter configured and dimensioned to form a chamber with the inner surface of the tube. The insert may define an interior cavity. The insert may include a transition diameter disposed intermediate the first diameter and the second diameter. The transition diameter can be substantially tapered relative to the longitudinal axis. The second diameter may include at least one radially extending rib being configured and dimensioned to engage the inner surface of the tube. The first diameter may have a larger dimension relative to the second diameter. The insert can be disposed adjacent the closed end.
    Type: Application
    Filed: August 7, 2002
    Publication date: February 12, 2004
    Inventors: John Liseo, Richard H. Hawley, Todd DeMatteo
  • Patent number: 6641993
    Abstract: Apparatus and a method for mixing a liquid within a disposable aspirating probe tip so that most of the liquid is forced to move past a transition zone between two different inside diameters to cause rotational mixing. The apparatus and method can be used to provide agglutination of blood, which in turn can be used for blood typing. The probe tip can comprise a single integral piece, or two separate portions. The transition zone can comprise a sharp demarcation between inside diameters, or a smooth one.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: November 4, 2003
    Assignee: Ortho Clinical Diagnostics, Inc.
    Inventors: Merrit N. Jacobs, Zhong Ding, Ronald F. Brookes
  • Publication number: 20030188590
    Abstract: Provided is a consolidometer and methods of its use. In its preferred embodiment, the device and methods permit accurate and convenient laboratory sampling of the selfweight consolidation of media, such as soft soil and soil slurries that may result from dredging operations. One option also provides for attaching sensors at locations along the consolidometer for taking data on additional characteristics of the media.
    Type: Application
    Filed: April 9, 2002
    Publication date: October 9, 2003
    Inventors: Landris T. Lee, Daniel A. Leavell, Mickey D. Blackmon
  • Publication number: 20030164051
    Abstract: A method and a device for sampling and storing a urine specimen capable of recovering a sampled urine specimen to a recovery container (5) through a filter (2) by the sucking pressure of the decompressed and enclosed recovery container (5); the device for sampling and storing the urine specimen, comprising a filter holder (3) having a space for storing the filter (2) for filtrating the urine specimen, the filter (2) stored therein, and the recovery container (5) decompressed and enclosed by a plug body (4), wherein hollow tubes (6) with a sharp tip communicating with a space (S) having the filter (2) stored therein is installed in the filter holder (3) on a specimen delivery side to the recovery container (5).
    Type: Application
    Filed: February 6, 2003
    Publication date: September 4, 2003
    Inventors: Noriaki Kunimune, Shinichi Yokoyama, Shigeaki Baba, Yasuro Kameno
  • Patent number: 6605257
    Abstract: A present micro array manufacturing apparatus includes a substrate placement portion 11 on which a plurality of substrates can be arranged, a tighter plate 12 for storing a solution including a living body sample, a solution storing member 52 for taking in the solution from the tighter plate 12 and storing the solution therein, and a needle 51 which can be inserted into the solution storing member 52 to allow the solution stored in the solution storing member 52 to adhere onto each of the substrates by a given quantity, wherein the solution storing member 52 and needle 51 are moved in directions where they approach and part away from the substrates to thereby form spots on the substrates. And, the individual operations of the solution storing member 52 and needle 51 are carried out by single drive means 32.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: August 12, 2003
    Assignees: THK Co., LTD, Riken
    Inventors: Touji Nakazawa, Akihiro Iimura, Hideo Tashiro, Tokuji Kitsunai, Yoshihide Hayashizaki
  • Patent number: 6598474
    Abstract: An adapter for holding a sample container includes a main body portion and a tapered body portion that forms a continuation of the main body portion. The tapered body portion includes a mouth opening that is of lesser diameter than the diameter of the main body portion. The mouth opening of the adapter is sized to provide direct support of a sample container which holds a liquid sample. During liquid level sensing ultrasonic waves from an ultrasound detector are reflected back to the sound detector as echoes from the lip flange of the sample container and from the liquid level within the sample container. The tapered surface of the adapter deflects sound echoes away from the sound detector. The adapter is thus invisible to the ultrasound detector. The echo from the liquid level is a variable duration echo and the echo from the lip flange of the sample container is a fixed duration echo that is always of lesser duration than the variable duration echo.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: July 29, 2003
    Assignee: Bayer Corporation
    Inventors: Paul E. Purpura, Thomas W. De Young
  • Patent number: 6576193
    Abstract: Devices and methods for collecting a fluid specimen and testing it are disclosed that avoid unduly exposing the tester to the specimen and eliminate the possibility of contaminating the remaining portion of the collected fluid. The device includes a first compartment for collecting the fluid and provides controlled volumes of fluid from the first compartment to a second compartment where the fluid is accessible to test strips. Fluid from the first compartment is transferred to the second compartment by use of a fluid metering valve having a valve cylinder with one or more wells formed on the surface of the cylinder. The fluid metering valve is fluidly connected to the first compartment at a first valve position and is fluidly connected to the second compartment at a second valve position.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: June 10, 2003
    Inventors: Shujie Cui, Alice H. Yu
  • Publication number: 20030089170
    Abstract: Methods and apparatus for simultaneous or sequential, rapid analysis of multiple samples by photoacoustic spectroscopy are disclosed. Particularly, a photoacoustic spectroscopy sample array vessel including a vessel body having multiple sample cells connected thereto is disclosed. At least one acoustic detector is acoustically positioned near the sample cells. Methods for analyzing the multiple samples in the sample array vessels using photoacoustic spectroscopy are provided.
    Type: Application
    Filed: November 13, 2001
    Publication date: May 15, 2003
    Applicant: Battelle Memorial Institute
    Inventors: James E. Amonette, S. Thomas Autrey, Nancy S. Foster-Mills
  • Publication number: 20030087447
    Abstract: A multiple cuvette strip comprises a plurality of wells and a reversible interlocking device. The well strips can be reversibly interlocked to other well strips to form a sample holder system. One embodiment of a well strip comprises a flange and a slot to form a reversible interlocking device.
    Type: Application
    Filed: November 8, 2001
    Publication date: May 8, 2003
    Inventors: Matthew R. Blouin, Robert R. Fisette
  • Patent number: 6539817
    Abstract: The invention provides a biological sampling and storage container which is easy and sanitary to use, may be shipped through regular mail, and includes a drying material or desiccant for drying feces samples that are stored therein. The sampling and storage container consists of a body having a sampling chamber and a drying chamber which are in gaseous communication with each other. Preferably, a sampling wand is frictionally retained in the sampling chamber and the drying material is disposed in the drying chamber.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: April 1, 2003
    Assignee: Meridian Bioscience, Inc.
    Inventors: Kenneth James Kozak, Ching Sui Arthur Yi
  • Publication number: 20030057368
    Abstract: The invention concerns the structure of the sample support plates for mass spectrometric analysis of organic samples ionized by matrix-assisted laser desorption. The invention consists of a highly flat plate, electrically conductive at least on its surface, rigidly bonded to a base structure in such a way that together they form a body having the external dimensions of a microtitre plate, but such that thermal distortions of the surface cannot occur. The base structure may have both depressions for frictional gripping by a robot as well as a machine-readable identifier.
    Type: Application
    Filed: August 16, 2002
    Publication date: March 27, 2003
    Applicant: Bruker Daltonik GmbH
    Inventors: Jochen Franzen, Jeus Rebettge
  • Patent number: 6534013
    Abstract: The present invention is generally directed to improved microfluidic devices and systems, and particularly to a microfluidic device which comprises a planar body structure, at least a first channel network comprising intersecting channels disposed within the body structure wherein the first channel network is contained within an area of the planar body structure that is less than about 6 cm2; and a holder assembly configured to receive the body structure, the holder assembly having at least one aperture disposed therethrough from an upper surface to a lower surface thereof, and wherein the body structure is fixedly mounted to the holder assembly.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: March 18, 2003
    Assignee: Caliper Technologies Corp.
    Inventor: Colin B. Kennedy
  • Patent number: 6524531
    Abstract: A hand-held, single-channel dispenser/aspirator is disclosed. The present dispenser/aspirator comprises a body portion for gripping the dispenser and a head portion. In some embodiments, the head portion includes a valve, a liquid conduit and a removable liquid reservoir. The liquid conduit places the liquid reservoir and the dispensing valve in fluid communication. A gas conduit received by the body portion of the dispenser is operable to pressurize the fluid reservoir, or draw a partial vacuum therein. Controls located on the body portion operate the dispenser. The liquid reservoir is advantageously disposed near the valve, so that a relatively short length of liquid conduit is required to operatively connect the reservoir and the dispensing valve, thereby improving the accuracy of the dispensing operation.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: February 25, 2003
    Assignee: Pharmacopeia, Inc.
    Inventor: Ilya Feygin
  • Publication number: 20030033892
    Abstract: A lid for a sample holder that includes a load port, a first flow channel, and a second flow channel. The first flow channel includes a first end connected to the load port and a second end that opens into a first reservoir of the sample holder. The second flow channel also includes a first end connected to the load port and a second end that opens into a second reservoir of the sample holder.
    Type: Application
    Filed: August 14, 2001
    Publication date: February 20, 2003
    Inventors: Michael Zwick, Heather Koshinsky
  • Patent number: 6520035
    Abstract: An apparatus is provided for extracting cross-sectional samples of bulk material from a moving belt conveyor with a rotating sample cutter. The sample cutter is driven around a circular sampling path by a pair of double-acting pneumatic cylinders that are connected to angularly offset crank throws. Fluid flow in and out of each pneumatic cylinder pressure chamber is independently regulated as a function of the respective cylinder rod position and direction of movement whereby both chambers may be simultaneously open to the pressure supply or to the atmospheric vent for a brief rotational arc.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: February 18, 2003
    Assignee: Heron Holdings
    Inventors: John B. Long, Armistead M. Long
  • Publication number: 20020194937
    Abstract: A soil sampler liner with areas of reduced wall thickness is defined by a continuous wall that has a reduced area extending along at least a portion of the length of the liner. The liner is inserted into the inner bore of a sampler probe, and a soil sample is taken by vertically inserting the probe and liner into the ground. The wall of the liner has at least two distinct areas of varying thickness; a reduced wall area and wall areas adjacent to the reduced wall area. The walls are sufficiently strong to withstand the forces applied to the liner when taking relatively large-diameter soil samples. The thickness of the wall at the reduced wall area is less than the thickness of the wall at the adjacent areas to permit a user to easily and safely cut through the wall at the reduced wall area and remove a large-diameter soil sample from the liner. The liner is also radially compressible into a flattened shape for compact and economical packaging and shipment of liners in relatively large quantities.
    Type: Application
    Filed: June 25, 2001
    Publication date: December 26, 2002
    Applicant: Kejr, Inc.
    Inventors: Gregory H. Scott, Thomas M. Christy, Michael B. Carlin
  • Publication number: 20020194938
    Abstract: A sample holder and auxiliary apparatus are provided to position and hold a sample in the sample holder. A method of positioning and holding a sample in the sample holder is also provided. The sample holder preferably includes a holder body having a sample holding portion arranged therein. An opening in the sample holding portion is configured to receive a sample therein. An elastic member is configured to supply a holding force to hold the sample in the opening. The auxiliary apparatus preferably includes one or more holder supports configured to support a sample holder. The auxiliary apparatus is configured to receive the sample holder and force a sample holding member of the sample holder into a rearward position to permit the sample holder to receive a sample into an opening thereof.
    Type: Application
    Filed: June 19, 2002
    Publication date: December 26, 2002
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Bon-Se Koo, Ho-Hyung Jung, Dae-Jung Kim
  • Patent number: 6480347
    Abstract: A plurality of magnets is provided in an illumination prism carrier of a transmitted light refractometer and a corresponding plurality of magnets is provided in a sample prism housing of the refractometer to align a light exit surface of the illumination prism relative to a sample surface of the sample prism and urge the optical surfaces together in an even and uniform manner. The magnets replace mechanical biasing arrangements for positioning the optical surfaces and function to consistently reproduce a measurement optical path in the instrument for improved accuracy and repeatability of measurements.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: November 12, 2002
    Assignee: Leica Microsystems Inc.
    Inventor: Erin D. Spring
  • Patent number: 6470967
    Abstract: A device (10) for collecting fluid samples from a subsurface (100), injecting fluids into a subsurface and measuring the hydrostatic pressure of groundwater in a subsurface is described. The device includes an outer tube (12) with a center bore (12D) and openings (12E) at one end (12B) and a rigid inner rod (18) configured to be telescopingly inserted into the center bore of the outer tube. The inner rod provides support and prevents damage to the outer tube during insertion into the subsurface. The device is inserted into the subsurface until the openings in the outer tube are adjacent the testing area. The inner rod is then removed from the outer tube. To collect fluid samples, the samples are retrieved from the fluid which has moved from the subsurface through the openings to the center bore of the outer tube. To inject fluid into the subsurface, the fluid is injected into the center bore and flows through the openings to the subsurface.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: October 29, 2002
    Inventor: Mark A. Henry
  • Publication number: 20020150509
    Abstract: The present invention provides a sampler for collecting a specimen of a substance. In one embodiment, the sampler comprises a sampler body, a platen having first and second opposing sides wherein the first side is coupleable to an end of the sampler body, and a sampling medium coupleable to the second side and configured to retain a specimen of a substance thereon.
    Type: Application
    Filed: April 17, 2001
    Publication date: October 17, 2002
    Inventors: Erik C. Houge, John M. McIntosh, Larry E. Plew, Fred A. Stevie, Catherine B. Vartuli
  • Publication number: 20020121139
    Abstract: An adapter for holding a sample container includes a main body portion and a tapered body portion that forms a continuation of the main body portion. The tapered body portion includes a mouth opening that is of lesser diameter than the diameter of the main body portion. The mouth opening of the adapter is sized to provide direct support of a sample container which holds a liquid sample. During liquid level sensing ultrasonic waves from an ultrasound detector are reflected back to the sound detector as echoes from the lip flange of the sample container and from the liquid level within the sample container. The tapered surface of the adapter deflects sound echoes away from the sound detector. The adapter is thus invisible to the ultrasound detector. The echo from the liquid level is a variable duration echo and the echo from the lip flange of the sample container is a fixed duration echo that is always of lesser duration than the variable duration echo.
    Type: Application
    Filed: March 2, 2001
    Publication date: September 5, 2002
    Inventors: Paul E. Purpura, Thomas W. De Young
  • Publication number: 20020110491
    Abstract: A piercing station for piercing sample container caps or thick stoppers is provided. The cap piercing station utilizes a piercing blade having a generally Z-shaped cross-section, a carriage assembly for moving the blade to pierce a cap on a container, an alignment block assembly for preventing the container from being lifted up by friction with the blade when the blade is being withdrawn from a pierced cap, and a latch assembly for latching the alignment block assembly when the blade is being withdrawn.
    Type: Application
    Filed: February 9, 2001
    Publication date: August 15, 2002
    Inventors: David L. Goodale, Steven P. Katzmann, William M. Robins
  • Patent number: 6432365
    Abstract: An automated sample-on-solid-support processing system includes a treatment solution supply subsystem which feeds solvent to a dispenser to dispense a measured amount of treatment solution to each well of a multi-well plate. The dispenser measures the solution within a fill container having a plurality of reservoir wells corresponding to the number of wells in the multi-well plate. The fill container is contained within a reservoir chamber that is filled with an excess of solution. Each reservoir well is surrounded by a plurality of bores which drains excess solution from the top of the fill container so that a precise amount of solution is left in the reservoir wells when solution is drained out of the reservoir chamber. Gas pressure is introduced into the reservoir chamber to force the solution out of the reservoir well through a bundle of tubes, with one tube per well, and into the wells of the multi-well plate.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: August 13, 2002
    Assignee: Discovery Partners International, Inc.
    Inventors: Robert Levin, Rob Neeper, John Bridwell
  • Patent number: 6428751
    Abstract: A sample cup assembly for use with an analytical instrument having a sample cup holder with an inner diameter which is greater than the outer diameter of the sample cup assembly. The sample cup assembly can include a main cell for retaining a specimen to be analyzed; a collar for locating a thin film over the open end of the main cell such that the film sealingly closes the open end of the main cell; and two or more projections extending outwardly from either the main cell or collar. The projections engage the interior surface of the sample cup holder when the sample cup assembly is installed therein, thereby centering the sample cup assembly within the sample cup holder.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: August 6, 2002
    Inventor: Monte J. Solazzi
  • Publication number: 20020046614
    Abstract: An apparatus for testing a specimen.
    Type: Application
    Filed: October 24, 2001
    Publication date: April 25, 2002
    Inventor: Kenneth Alley
  • Publication number: 20010054324
    Abstract: A sampling device comprising an elongate tube and an identification device. The identification device comprises a transponder which is removably attached to the tube by means of a clip. The identification device may thus be removed from the tube prior to analysis and/or replaced between successive sampling operations.
    Type: Application
    Filed: May 14, 2001
    Publication date: December 27, 2001
    Inventors: Alun Cole, Elizabeth Angela Woolfenden
  • Patent number: 6305482
    Abstract: A pressure and temperature core sampler comprises a tool for recovering cores specifically enabling the evaluation of methane hydrate resources. Because methane hydrate tends to decompose under conditions of pressure decrease and/or temperature increase as the samples are retrieved to the surface, a coring tool in accordance with the present invention provides a self-contained system for retrieving core samples at or near in situ pressure while cooling the core sample. The coring tool is preferably a wire line retrievable device that provides for nearly continuous coring during the drilling operation.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: October 23, 2001
    Inventors: James T. Aumann, Craig R. Hyland
  • Patent number: 6293159
    Abstract: An apparatus for delivering fluids at a precisely controlled rate which includes a fluid dispensing component having a fluid reservoir for containing the fluids to be delivered and a reservoir fill component which can be removably interconnected with the fluid dispensing component. The reservoir fill assembly is uniquely designed to accept a vial component of conventional construction which is factory filled with the medicinal fluid to be delivered to the patient. The dispenser component embodies a highly novel fluid flow indicator that provides a readily discernible visual indication of fluid flow status through the device.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: September 25, 2001
    Assignee: Science Incorporated
    Inventors: Marshall S. Kriesel, Steven M. Arnold, James Garrison, Farhad Kazemzadeh
  • Publication number: 20010008614
    Abstract: A sample collection system capable of collecting, storing and dispensing a liquid sample is disclosed. The collection system includes a collector composed of a material which has the unique ability to express constituents of interest at levels which are much more concentrated than their levels in the fluid samples from which they are expressed, where the expressed highly concentrated sample can then be used with modern rapid screening/testing protocols, such as solid phase assays, to test for the constituents of interest. Thus, it is now possible to obtain analytes of interest, such as the HIV protein antibodies, from saliva samples at concentrations that are representative of that found in serum or plasma. The collector is sized and shaped to fit within a recovery container, which, in turn, is sized and shaped to fit within a collection tube.
    Type: Application
    Filed: November 16, 1998
    Publication date: July 19, 2001
    Inventor: JACK L. ARONOWITZ