Nanoparticle (structure Having Three Dimensions Of 100 Nm Or Less) Patents (Class 977/773)
  • Patent number: 9433591
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising a metal ion, a biguanide, an oxidant, and water; optionally further comprising an alpha-amino acid or a nucleobase; is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of metal-containing nanoparticles. Biocompatible nanoparticles comprised of cerium and a biguanide, and optionally containing an alpha-amino acid or a nucleobase, are also described. The use of metal oxide nanoparticles comprising a biguanide as a nanoparticle core/corona in the preparation of nanoscale ionic (liquid) material compositions is disclosed.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: September 6, 2016
    Assignee: CERION, LLC
    Inventors: Kenneth Joseph Reed, Ashley Renée Versaggi, Wendi Ann Costanzo
  • Patent number: 9120710
    Abstract: Reactive nanocomposites, foams, and structures comprising functionalized metal nanoparticles that are incorporated into a fluorinated polymer matrix using an in-situ polymerization process and methods of making and using the same. The reactive nanocomposites, foams, and structures according to the present invention demonstrate enhanced mechanical properties due to the direct chemical integration of the nano-metal fuel particles into the fluoropolymer matrix. In addition, the reactive nanocomposites, foams, and structures may be processed using conventional polymer processing and may be used to fabricate materials such as reactive liners, casings, and other components and inserts. The intense heat produced during reaction may further be used in a variety of applications such as disinfection, decontamination, and/or destruction.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: September 1, 2015
    Assignee: The United States of America as represented by the Secretary of the Air Force
    Inventors: Christopher A. Crouse, Jonathan E. Spowart, Christian J. Pierce, Breanna K. Hardenstein
  • Publication number: 20150148870
    Abstract: The present invention discloses a method for preparing noble metal nanoparticles, comprising the following steps: a) preparing an Olea Europaea fruit extract; b) preparing an Acacia Nilotica extract; c) mixing the Olea Europaea fruit extract and the Acacia Nilotica extract for preparing a mixed extract; d) providing an aqueous solution containing a noble metal compound dissolved therein; e) mixing the mixed extract obtained in step c) and the aqueous solution of step d) to form noble metal nanoparticles; noble metal nanoparticles obtained thereby and their use.
    Type: Application
    Filed: September 15, 2014
    Publication date: May 28, 2015
    Inventors: Awatif Ahmed HENDI, Manal A. AWAD, Nada E. EISA, Khaled M. ORTASHI
  • Patent number: 9038829
    Abstract: The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the following steps. First, the sorbent material is provided. The sorbent material, in one embodiment, is nano-particles. In a preferred embodiment, the nano-particles are unstabilized nano-Se. Next, the sorbent material is exposed to mercury in an environment. As a result, the sorbent material captures and stabilizes mercury from the environment. In the preferred embodiment, the environment is an indoor space in which a fluorescent has broken.
    Type: Grant
    Filed: October 7, 2008
    Date of Patent: May 26, 2015
    Assignee: Brown University
    Inventors: Robert H. Hurt, Steven P. Hamburg, Love Sarin, Indrek Kulaots
  • Patent number: 9041032
    Abstract: An exemplary embodiment of the present invention includes a light emitting diode including a strain-enhanced well layer. The light emitting diode includes an n-contact layer, an active layer having a barrier layer and a well layer, a p-contact layer, and a strain-enhancing layer configured to enhance a strain applied to the well layer.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: May 26, 2015
    Assignee: Seoul Viosys Co., Ltd.
    Inventors: Joo Won Choi, Yoo Dae Han, Jeong Hun Heo
  • Patent number: 9040428
    Abstract: Hemispheres and spheres are formed and employed for a plurality of applications. Hemispheres are employed to form a substrate having an upper surface and a lower surface. The upper surface includes peaks of pillars which have a base attached to the lower surface. The peaks have a density defined at the upper surface by an array of hemispherical metal structures that act as a mask during an etch to remove substrate material down to the lower surface during formation of the pillars. The pillars are dense and uniform and include a microscale average diameter. The spheres are formed as independent metal spheres or nanoparticles for other applications.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: May 26, 2015
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Augustin J. Hong, Woo-Shik Jung, Jeehwan Kim, Jae-Woong Nahum, Devendra K. Sadana
  • Patent number: 9040156
    Abstract: This invention relates to whitlockite and a method for manufacturing the same. The method includes adding, to water, a calcium ion supplying material and a cation supplying material containing a cation (X) other than the calcium ion to prepare a cation aqueous solution, adding a phosphoric acid supplying material to the cation aqueous solution, and aging the cation aqueous solution including the phosphoric acid supplying material. As a result, whitlockite having high purity and high crystallinity can be mass produced using a simple process.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: May 26, 2015
    Assignee: SNU R&DB FOUNDATION
    Inventors: Kug Sun Hong, Ki Tae Nam, Hae Lin Jang, Hyun Seung Ryu, Kyoung Suk Jin
  • Patent number: 9040449
    Abstract: Nanoparticle catalyst compositions and methods for preparation of same are described. The nanoparticle catalysts are platinum-free and are useful in effecting selective ring-opening reactions, for example in upgrading heavy oil. The catalyst may be of monometallic composition, or may comprise an alloyed or core-shell bimetallic composition. The nanoparticles are of controlled size and shape.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: May 26, 2015
    Assignee: Governors of the University of Alberta
    Inventors: Natalia Semagina, Xing Yin, Jing Shen, Kavithaa Loganathan
  • Patent number: 9040105
    Abstract: A process for the production of nanocrystals or amorphous nanoparticles of actives (nanomaterials), especially from the peels of grapes. A dispersion of a micrometer-sized material in a solution of surfactant or a steric stabilizer is first provided. The macrosuspension is then stirred for at least 1 minute at a rotational speed above 500 rpm using a rotor-stator mixer. The stirred mixture is passed through a jet stream or piston-gas type high pressure homogenizer. The nanomaterials produced can be incorporated into formulations for use as nutraceutical, nutritional supplement, or as supportive treatment in medical therapy. The active can be derived from the peels of grapes.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: May 26, 2015
    Assignee: PHARMASOL GMBH
    Inventor: Cornelia Keck
  • Patent number: 9040158
    Abstract: A generic route for synthesis of asymmetric nanostructures. This approach utilizes submicron magnetic particles (Fe3O4—SiO2) as recyclable solid substrates for the assembly of asymmetric nanostructures and purification of the final product. Importantly, an additional SiO2 layer is employed as a mediation layer to allow for selective modification of target nanoparticles. The partially patched nanoparticles are used as building blocks for different kinds of complex asymmetric nanostructures that cannot be fabricated by conventional approaches. The potential applications such as ultra-sensitive substrates for surface enhanced Raman scattering (SERS) have been included.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: May 26, 2015
    Assignee: UChicago Argonne LLC
    Inventors: Yugang Sun, Yongxing Hu
  • Publication number: 20150139894
    Abstract: The following invention relates to a novel and efficient nanoparticles synthesis reactor and process production. More particularly, the present invention is applied to the synthesis of nanostructured tin dioxide. The benefits provided by the invention can be seen in various gaseous reactions where occurs the formation of solid and gaseous phases.
    Type: Application
    Filed: May 6, 2013
    Publication date: May 21, 2015
    Inventors: Diego Manuel Ferreira Lusquinos Fontanez, Francisco José Moura
  • Patent number: 9034169
    Abstract: The method for detection of cyanide in water is a method for the detection of a highly toxic pollutant, cyanide, in water using ZnO2 nanoparticles synthesized locally by an elegant Pulsed Laser Ablation technique. ZnO2 nanoparticles having a median size of 4 nm are synthesized from pure zinc metal target under UV laser irradiation in a 1-10% H2O2 environment in deionized water. The synthesized ZnO2 nanoparticles are suspended in dimethyl formamide in the presence of Nafion, and then ultrasonicated to create a homogenous suspension, which is used to prepare a thin film of ZnO2 nanoparticles on a metal electrode. The electrode is used for cyanide detection.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 19, 2015
    Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventors: Mohammed Ashraf Gondal, Qasem Ahmed Qasem Drmosh, Z. H. Yamani, Tawfik Abdo Saleh
  • Patent number: 9034354
    Abstract: Provided are antibacterial and antimicrobial surface coatings and dental materials by utilizing the antimicrobial properties of copper chalcogenide and/or copper halide (CuQ, where Q=chalcogens including oxygen, or halogens, or nothing). An antimicrobial barrier is created by incorporation of CuQ nanoparticles of an appropriate size and at a concentration necessary and sufficient to create a unique bioelectrical environment. The unique bioelectrical environment results in biocidal effectiveness through a multi-factorial mechanism comprising a combination of the intrinsic quantum flux of copper (Cu0, Cu1+, Cu2+) ions and the high surface-to-volume electron sink facilitated by the nanoparticle. The result is the constant quantum flux of copper which manifests and establishes the antimicrobial environment preventing or inhibiting the growth of bacteria.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: May 19, 2015
    Assignees: MUSC Foundation for Research Development, Clemson University
    Inventors: Walter George Renne, Anthony Samuel Mennito, Michael Gerard Schmidt, Jompobe Vuthiganon, George Chumanov
  • Patent number: 9034206
    Abstract: Disclosed is a halogen silicate luminescent material having a chemical structural formula of (N1?a?bEuaMnb)10Si6O21Cl2 with xM nanoparticles, and the preparation method thereof, where M is at least one of Ag, Au, Pt and Pd, N is an alkaline earth metal and specifically at least one of Mg, Ca, Sr and Ba, 0<x?1×10?2, 0 M<a?0.3, and 0<b<0.3. The above halogen silicate luminescent material having the core-shell structure utilizes the surface plasmon resonance generated by the surface of metal nanoparticles.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: May 19, 2015
    Assignee: Ocean's King Lighting Science & Technology Co., Ltd.
    Inventors: Mingjie Zhou, Jun Liu, Wenbo Ma
  • Patent number: 9034073
    Abstract: A method for making a metal-based nano-composite material is disclosed. In the method, a semi-solid state metal-based material is provided. The semi-solid state metal-based material is stirred and nano-sized reinforcements are added into the semi-solid state metal-based material to obtain a semi-solid state mixture. The semi-solid state mixture is heated to a temperature above a liquidus temperature of the metal-based material, to achieve a liquid-metal-nano-sized reinforcement mixture. The liquid-metal-nano-sized reinforcement mixture is ultrasonically processed at a temperature above the liquidus temperature by conducting ultrasonic vibrations to the liquid-metal-nano-sized reinforcement mixture along different directions at the same time.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: May 19, 2015
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Wen-Zhen Li, Shi-Ying Liu
  • Patent number: 9034215
    Abstract: The present invention provides a noble metal fine particle with a protein adsorbed thereon, including a noble metal fine particle, and a protein adsorbed on a surface of the noble metal fine particle. The protein has an isoelectric point in a range of pH 4.0 to 7.5. An amount of the protein adsorbed is in a range of 3 to 55.1 wt % with respect to a total weight of the noble metal fine particle and the protein. The noble metal fine particle with a protein adsorbed thereon according to the present invention has excellent redispersibility.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: May 19, 2015
    Assignee: Nippon Sheet Glass Company, Limited
    Inventors: Ryohei Ogawa, Kiyoshi Miyashita, Masamichi Kezuka
  • Patent number: 9034380
    Abstract: Materials and Methods are disclosed for producing nanoparticles linked to antibacterial ligands, including antibiotics and/or molecules which bind to bacterial markers, and for the use of the nanoparticles for the treatment of conditions treatable by the antibiotic ligands.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: May 19, 2015
    Assignee: Midatech Ltd.
    Inventors: Thomas William Rademacher, Godfrey Bradman, Soledad Penades Ullate, Rafael Ojeda Martinez De Castilla
  • Patent number: 9029016
    Abstract: Provided are a negative active material, a method of preparing the same, and a lithium battery including the negative active material. The negative active material includes a carbonaceous core that has a sulfur content of about 10 ppm to 900 ppm; and an amorphous carbon layer continuously formed on a surface of the carbonaceous core, wherein the carbonaceous core has a crystalloid plate structure, and a crystallite size measured from a full width at half maximum of the peak with respect to the surface (002) of about 10 nm to about 45 nm in an X-ray diffraction spectrum of the carbonaceous core. The lithium battery including a negative electrode including the negative active material has improved capacity characteristics and ring lifetime characteristics.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: May 12, 2015
    Assignee: Samsung SDI Co., Ltd.
    Inventors: So-Ra Lee, Chang-Su Shin, Ui-Song Do, Beom-Kwon Kim, Jae-Myung Kim
  • Patent number: 9028880
    Abstract: The invention provide a silica nanoparticle comprising a non-porous matrix of silicon-oxygen bonds, wherein the matrix comprises organic agents conjugated to silicon or oxygen atoms in the matrix, the organic agents are conjugated to the matrix through linker L groups, wherein the linker L comprises, for example, an ester, urea, thiourea, or thio ether group, and wherein the diameter of the nanoparticle is about 15 nm to about 200 nm. The invention also provides novel methods of making and using the silica nanoparticles described herein.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: May 12, 2015
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Jianjun Cheng, Li Tang
  • Patent number: 9028873
    Abstract: The present disclosure relates to compositions and methods for producing nanoparticles to provide relatively more rapid delivery of such particles across the blood-brain barrier. The nanoparticles may be formed from bis-quaternary pyridinium-aldoxime salts that may also be of a specific polymorphic structure and which may be formed in either hydrophobic or hydrophilic type liquid media. In addition, the nanoparticle for transport across the blood-brain barrier may comprise a polymeric resin encapsulating a bis-quaternary pyridinium-2-aldoxime salt.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: May 12, 2015
    Assignee: Southwest Research Institute
    Inventors: Joseph A. McDonough, Hong Dixon, Larry A. Cabell
  • Patent number: 9028957
    Abstract: Embodiments of the present disclosure relate to the preparation of colloidal dispersions or suspensions of inorganic materials with nano-sized and nano-structured morphologies, preferably the nanosheet form, compositions produced by this method, and the like.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: May 12, 2015
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Tina T. Salguero, Darrah Johnson-McDaniel, Christopher A. Barrett
  • Patent number: 9029936
    Abstract: A memory device includes a semiconductor channel, a tunnel dielectric layer located over the semiconductor channel, a first charge trap including a plurality of electrically conductive nanodots located over the tunnel dielectric layer, dielectric separation layer located over the nanodots, a second charge trap including a continuous metal layer located over the separation layer, a blocking dielectric located over the second charge trap, and a control gate located over the blocking dielectric.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: May 12, 2015
    Assignee: SanDisk Technologies Inc.
    Inventors: Vinod Purayath, George Samachisa, George Matamis, James Kai, Yuan Zhang
  • Patent number: 9029355
    Abstract: In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about 50 nm to about 500 nm.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: May 12, 2015
    Assignee: Marinus Pharmaceuticals
    Inventors: Kenneth Shaw, Mingbao Zhang
  • Patent number: 9023388
    Abstract: A high-efficacy, long-acting formulation of silibinin, comprising silibinin solid dispersion, silibinin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the mass ratio of these components is silibinin solid dispersion:silibinin-loaded silica nanoparticles:slow-release matrix material:release enhancer=1:0.5˜1.25:0.1˜0.3:0.1˜0.3; the drug loading rate of the said silibinin-loaded silica nanoparticles is 51.29˜51.77%; the said silibinin solid dispersion contains povidone K30, soybean lecithin, acrylic resin IV, wherein the mass ratio between silibinin and other medical accessories is silibinin:povidone K30:soybean lecithin:acrylic resin IV=1:1˜3:0.3˜0.8:0.2˜0.5. Compared with the existing formulations, the half life of the high-efficacy, long-acting formulation of silibinin disclosed in this invention is 14.8 times longer while the mean residence time (MRT) of which is 4.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: May 5, 2015
    Assignee: Jiangsu University
    Inventors: Ximing Xu, Jiangnan Yu, Xia Cao, Yuan Zhu
  • Patent number: 9023457
    Abstract: Described herein are various methods for making textured articles, textured articles that have improved fingerprint resistance, and methods of using the textured articles. The methods generally make use of masks comprising nanostructured metal-containing features to produce textured surfaces that also comprise nanostructured features. These nanostructured features in the textured surfaces can render the surfaces hydrophobic and oleophobic, thereby beneficially providing the articles with improved fingerprint resistance relative to similar or identical articles that lack the texturing.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: May 5, 2015
    Assignee: Corning Incorporated
    Inventors: Albert Carrilero, Prantik Mazumder, Johann Osmond, Valerio Pruneri, Paul Arthur Sachenik, Lili Tian
  • Patent number: 9023469
    Abstract: Basic zinc cyanurate fine particles are produced by subjecting a mixed slurry to wet dispersion using a dispersion medium at a temperature in the range of 5 to 55° C., the mixed slurry being formed by blending water, cyanuric acid, and at least one component selected from zinc oxide and basic zinc carbonate such that the cyanuric acid concentration is 0.1 to 10.0 mass % with respect to water.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: May 5, 2015
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Isao Oota, Masaki Oiwamoto, Takeshi Suwa
  • Patent number: 9023886
    Abstract: Provided are compositions and methods for preparation and administration of an oral nanosuspension of a poorly soluble drug with improved bioavailability. The method is optimized through microfluidization process with water soluble polymeric excipients in the absence of surfactants.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: May 5, 2015
    Assignee: Celgene Corporation
    Inventors: Ming J. Chen, Ho-Wah Hui, Thomas Lee, Paul Kurtulik, Sekhar Surapaneni
  • Patent number: 9023659
    Abstract: Disclosed is a quantum dot-embedded silica nanoparticle having plural quantum dots embedded within the silica nanoparticle, wherein the number of quantum dots existing in a concentric area within 10% of a radius from a center of the silica nanoparticle accounts for 10 to 70% of the number of total quantum dots embedded in the silica nanoparticle.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: May 5, 2015
    Assignee: Konica Minolta Medical & Graphic, Inc.
    Inventors: Takuji Aimiya, Masaru Takahashi
  • Patent number: 9017728
    Abstract: Disclosed are stable corticosteroid nanoparticulate formulations, methods of making and therapeutic uses thereof.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: April 28, 2015
    Assignee: Marinus Pharmaceuticals
    Inventors: Kenneth Shaw, Mingbao Zhang
  • Patent number: 9012519
    Abstract: The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human serum albumin and/or deferoxamine. The human serum albumin is present in an amount effective to reduce one or more side effects associated with administration of the pharmaceutical composition. The invention also provides methods for reducing one or more side effects of administration of the pharmaceutical composition, methods for inhibiting microbial growth and oxidation in the pharmaceutical composition, and methods for enhancing transport and binding of a pharmaceutical agent to a cell.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: April 21, 2015
    Assignee: Abraxis Bioscience, LLC
    Inventors: Neil P. Desai, Patrick Soon-Shiong, Vuong Trieu
  • Patent number: 9012518
    Abstract: The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human serum albumin and/or deferoxamine. The human serum albumin is present in an amount effective to reduce one or more side effects associated with administration of the pharmaceutical composition. The invention also provides methods for reducing one or more side effects of administration of the pharmaceutical composition, methods for inhibiting microbial growth and oxidation in the pharmaceutical composition, and methods for enhancing transport and binding of a pharmaceutical agent to a cell.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: April 21, 2015
    Assignee: Abraxis BioScience, LLC
    Inventors: Neil P. Desai, Patrick Soon-Shiong, Vuong Trieu
  • Patent number: 9012424
    Abstract: The present invention relates to a polymer according to Formulas (1) or (2): The present invention further relates to nanogels and nanoparticles made of a polymer according to general Formulas (1) and (2). The nanogels may comprise a biologically active component such as siRNA, miRNA, DNA, an (oligo)peptide or a proteins.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: April 21, 2015
    Assignee: 20MED Therapeutics B.V.
    Inventors: Johannes Franciscus Joseph Engbersen, Arkadi Vladimirovich Zinchenko
  • Patent number: 9011572
    Abstract: A method of generating hydrogen gas from the reaction of stabilized aluminum nanoparticles with water is provided. The stabilized aluminum nanoparticles are synthesized from decomposition of an alane precursor in the presence of a catalyst and an organic passivation agent, and exhibit stability in air and solvents but are reactive with water. The reaction of the aluminum nanoparticles with water produces a hydrogen yield of at least 85%.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: April 21, 2015
    Assignee: University of Dayton
    Inventors: Christopher E. Bunker, K. A. Shiral Fernando, Elena A. Guliants, Marcus J. Smith, Barbara A. Haruff
  • Patent number: 9011710
    Abstract: Methods are disclosed for synthesizing nanocomposite materials including ferromagnetic nanoparticles with polymer shells formed by controlled surface polymerization. The polymer shells prevent the nanoparticles from forming agglomerates and preserve the size dispersion of the nanoparticles. The nanocomposite particles can be further networked in suitable polymer hosts to tune mechanical, optical, and thermal properties of the final composite polymer system. An exemplary method includes forming a polymer shell on a nanoparticle surface by adding molecules of at least one monomer and optionally of at least one tethering agent to the nanoparticles, and then exposing to electromagnetic radiation at a wavelength selected to induce bonding between the nanoparticle and the molecules, to form a polymer shell bonded to the particle and optionally to a polymer host matrix. The nanocomposite materials can be used in various magneto-optic applications.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: April 21, 2015
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Palash Gangopadhyay, Alejandra Lopez-Santiago, Robert A. Norwood
  • Patent number: 9006292
    Abstract: The present invention provides methods of regulating physiological and metabolic parameters and of treating diseases by administering metadichol to a subject in need of such regulation and/or treatment. Metadichol can be administered as a liquid or gel formulation.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: April 14, 2015
    Assignee: NanoRx, Inc.
    Inventor: Palayakotai R. Raghavan
  • Patent number: 9005756
    Abstract: Disclosed are block copolymer nanostructures formed on surface patterns different from nanostructure of the block copolymer and preparation methods thereof.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: April 14, 2015
    Assignee: Advanced Institute of Science and Technology
    Inventors: Sang Ouk Kim, Dong Ok Shin, Bong Hoon Kim
  • Patent number: 9005814
    Abstract: Highly dispersed lithium titanate crystal structures having a thickness of few atomic layers level and the two-dimensional surface in a plate form are supported on carbon nanofiber (CNF). The lithium titanate crystal structure precursors and CNF that supports these are prepared by a mechanochemical reaction that applies sheer stress and centrifugal force to a reactant in a rotating reactor. The mass ratio between the lithium titanate crystal structure and carbon nanofiber is preferably between 75:25 and 85:15. The carbon nanofiber preferably has an external diameter of 10-30 nm and an external specific surface area of 150-350 cm2/g. This composite is mixed with a binder and then molded to obtain an electrode, and this electrode is employed for an electrochemical element.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: April 14, 2015
    Assignee: Nippon Chemi-Con Corporation
    Inventors: Katsuhiko Naoi, Wako Naoi, Shuichi Ishimoto, Kenji Tamamitsu
  • Patent number: 9005664
    Abstract: The present invention is directed to co-assembled nanoparticle composition comprising denatured ?-lactoglobulin and at least one nutraceutical compound, specifically polyphenols, such as EGCG, compositions comprising same and methods of preparing thereof.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: April 14, 2015
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Yoav D. Livney, Avi Shpigelman
  • Patent number: 9005480
    Abstract: The present invention describes a solventless ligand exchange using a siloxane polymer having a binding ligand that displaces the binding ligand on a quantum dot material.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 14, 2015
    Assignee: Nanosys, Inc.
    Inventors: Paul T. Furuta, Robert Dubrow
  • Publication number: 20150099117
    Abstract: Methods for producing nanoparticles of metal alloys and the nanoparticles so produced are provided. The methods include addition of surfactant and cationic metal to a novel reagent complex between zero-valent metal and a hydride. The nanoparticles of zero-valent metal alloys produced by the method include ˜7 nm zero-valent manganese-bismuth useful in fabricating a less expensive permanent magnet.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 9, 2015
    Applicant: Toyota Motor Engineering & Manufacturing North America, Inc.
    Inventors: Michael Paul Rowe, Daniel Jeffrey Herrera
  • Patent number: 8999207
    Abstract: The invention relates to a metallic, conductive ink for ink-jet printing, comprising a metal precursor material, in particular an organometallic decomposition compound, and a thermally decomposable polymer dissolved in an organic solvent, wherein a polymer having a decomposition temperature Tc<150° C. is contained as the thermally decomposable polymer. The polymer is selected from a cyclic polyacetal having blocked terminal groups, a cyclic polyaldehyde comprising bifunctional monomers, such as polyphthalaldehyde, polyglutaraldehyde, polysuccinaldehyde, and a polymeric glyoxylic acid, or a glyoxylic acid derivative, such as poly(methyl glyoxylate). The monomeric depolymerization products of the thermally decomposable polymer are used as reductants for the metal precursor material. The invention further relates to a method for producing the ink.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: April 7, 2015
    Assignee: Joanneum Research Forschungsgesellschaft mbH
    Inventors: Stefan Köstler, Daniela Wachter, Heinz Pichler, Andreas Rudorfer
  • Patent number: 8999206
    Abstract: Metal nanoparticles having improved migration resistance are provided. The present invention relates to a method for manufacturing composite nanoparticles including obtaining composite nanoparticles containing at least silver and copper in a single particle by heat treating a mixture containing an organic silver compound and an organic copper compound at a temperature of 150° C. or more in a non-oxidative atmosphere in the presence of a tertiary amine compound represented by the general formula R1R2R3N (wherein R1 through R3 are optionally substituted alkyl groups or aryl groups that may be the same or different, R1 through R3 may be linked in a ring, and the number of carbon atoms in each of R1 through R3 is 5 through 18 and may be the same or different).
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: April 7, 2015
    Assignees: Osaka Municipal Technical Research Institute, Daiken Chemical Co., Ltd.
    Inventors: Masami Nakamoto, Mari Yamamoto, Yukiyasu Kashiwagi, Yukio Yoshida, Hiroshi Kakiuchi, Shinsuke Matsumura
  • Patent number: 8999574
    Abstract: A method of preparing a graphene-sulfur nanocomposite for a cathode in a rechargeable lithium-sulfur battery comprising thermally expanding graphite oxide to yield graphene layers, mixing the graphene layers with a first solution comprising sulfur and carbon disulfide, evaporating the carbon disulfide to yield a solid nanocomposite, and grinding the solid nanocomposite to yield the graphene-sulfur nanocomposite. Rechargeable-lithium-sulfur batteries having a cathode that includes a graphene-sulfur nanocomposite can exhibit improved characteristics. The graphene-sulfur nanocomposite can be characterized by graphene sheets with particles of sulfur adsorbed to the graphene sheets. The sulfur particles have an average diameter of less than 50 nm.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: April 7, 2015
    Assignee: Battelle Memorial Institute
    Inventors: Jun Liu, John P. Lemmon, Zhenguo Yang, Yuliang Cao, Xiaolin Li
  • Patent number: 8999577
    Abstract: Provided are a negative active material, a method of preparing the same, and a lithium battery including the negative active material. The negative active material includes a carbonaceous core that has a sulfur content of about 10 ppm to 900 ppm; and an amorphous carbon layer continuously formed on a surface of the carbonaceous core, wherein the carbonaceous core has a crystalloid plate structure, and a crystallite size measured from a full width at half maximum of the peak with respect to the surface (002) of about 10 nm to about 45 nm in an X-ray diffraction spectrum of the carbonaceous core. The lithium battery including a negative electrode including the negative active material has improved capacity characteristics and ring lifetime characteristics.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: April 7, 2015
    Assignee: Samsung SDI Co., Ltd.
    Inventors: So-Ra Lee, Chang-Su Shin, Ui-Song Do, Beom-Kwon Kim, Jae-Myung Kim
  • Patent number: 8999295
    Abstract: Provided herein is a composition, a method, and a system for delivering a functional molecule to the cytosol of a cell, comprising a liposome configured to be taken into a cell, including by a process selected from the group consisting of endocytosis, pinocytosis or phagocytosis, the liposome comprising a phase transforming liquid with vapor pressure capable of forming a gas at low pressure, said liquid being associated with the liposome, and the liposome further comprising at least one functional molecule selected from the group consisting of a therapeutic molecule, a detectable label, and a targeting molecule.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: April 7, 2015
    Assignee: Brigham Young University
    Inventors: William G. Pitt, Ghaleb Husseini
  • Patent number: 8992739
    Abstract: A method for manufacturing a silicon-based nanocomposite anode active material for the lithium secondary battery and the lithium secondary battery using same, comprising the following steps: a first step of mounting a silicon-based wire between two electrodes, which are placed in a methanol-based solvent atmosphere, and manufacturing a dispersion solution in which silicon-based nanoparticles are dispersed by means of high-voltage pulse discharging; and a second step of manufacturing a silicon-based nanocomposite body by compositing the silicon-based nanoparticles in the solution and a different type of material.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: March 31, 2015
    Assignee: Korea Electrotechnology Research Institute
    Inventors: Yoon-cheol Ha, Chil-hoon Doh, Chu-hyun Cho
  • Patent number: 8992880
    Abstract: [Subject] Manufacturing onion-like carbon at a low cost. [Means for Realizing Subject] According to the invention, DLC powder, which is hard carbon powder, is produced by plasma CVD using a hydrocarbon gas as a material gas, in a first step, i.e. a DLC powder producing processing step. Then, in a second step, i.e. a DLC-to-OLC converting processing step, the DLC powder is heated in a vacuum or in an inert gas atmosphere to thereby convert the DLC powder into OLC. Like this, according to the invention, since a hydrocarbon gas can be used as a starting material to manufacture OLC, OLC can be manufactured at a significantly low cost.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: March 31, 2015
    Assignees: Shinko Seiki Company, Limited
    Inventors: Nobuyuki Terayama, Nobuo Ohmae
  • Patent number: 8993057
    Abstract: Silica-dysprosium oxide core-shell nanoparticles and a method for preparing the silica-dysprosium oxide core-shell nanoparticles are disclosed. Initially, ethyl silicate, n-butanol, ethylenediamine, and distilled water are mixed in the presence of ultrasonic radiation to prepare silica nanoparticles. Then, the silica nanoparticles are isolated. Next, the isolated silica nanoparticles, an acid, n-butanol, and dysprosium oxide are mixed in the presence of ultrasonic radiation to prepare silica-dysprosium oxide core-shell nanoparticles. Finally, the silica-dysprosium oxide core-shell nanoparticles are isolated.
    Type: Grant
    Filed: October 22, 2011
    Date of Patent: March 31, 2015
    Inventors: Masoud Salavati-Niasari, Fatemeh Davar, Morteza Enhessari, Mohammad Javad Esfahani
  • Patent number: 8991992
    Abstract: An aqueous latex ink includes a polymer latex having a particle size of less than about 100 nm. A method of making an aqueous latex ink includes emulsifying a polymer without the use of a surfactant to prepare a latex having a particle size of less than 100 nm. A method of printing an image on a substrate includes applying an aqueous latex ink to an intermediate receiving member using an inkjet printhead, spreading the ink onto the intermediate receiving member, inducing a property change of the ink, and transferring the ink to a substrate, wherein the ink comprises a latex having a particle size of less than about 100 nm.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: March 31, 2015
    Assignee: Xerox Corporation
    Inventors: Barkev Keoshkerian, Daryl W. Vanbesien, Michelle N. Chretien, Marcel P. Breton, Jenny Eliyahu
  • Patent number: 8992681
    Abstract: Disclosed is a system or method for efficiently manufacturing construction materials using carbon nanomaterials. In one or more embodiments, the method comprises creating a blend of carbon nanomaterials, wherein the blend of the carbon nanomaterials includes at least one of a carbon nanofiber, a carbon nanotube, a graphite nanoparticle and an amorphous carbon. The method also includes dispersing the carbon nanomaterials and adding a plasticizer and a sand to the dispersed mixture within 3 minutes. The method also includes adding at least one of water and a cement binding agent to the dispersed mixture after the plasticizer and the sand have been added.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: March 31, 2015
    Assignee: King Abdulaziz City for Science and Technology
    Inventors: Mohammed A. Binhussain, Turki Saud Mohammed Al-Saud, Siarhei Zhdanok, Andrei Krauklis, Petr Samtsou, Eduard Batsianouski