Abstract: A dispensing container comprising a molded plastic bottle and a cap. The molded plastic bottle has a top closed end, a cylindrical side wall, and a shoulder section at a dispensing end of the side wall. The shoulder has one or more indented portions which form the positioning lugs in the shoulder section. The plastic bottle also has a neck with external threads defining a mouth. The cap is selectively connected to the neck. The cap has an internally threaded cuff for interconnection with the external threads of the neck. The cap also has structure for dispensing of an enclosed material which is near the mouth. The cap is cup-shaped with a face and a cylindrical wall extending from the face to define an interior of the cap. When the cap is connected to the neck, the indented portions which form the positioning lugs in the shoulder are hidden from view within the interior of the cap.
Type:
Grant
Filed:
February 21, 1997
Date of Patent:
February 9, 1999
Assignee:
Bristol-Myers Squibb Company
Inventors:
Thomas M. Redmond, Sr., Timothy E. Fitten, Linda C. Nash, Robin Laraine Doyle
Abstract: The invention provides compositions and methods containing novel bis-(2,4-diaminophenoxy)benzene coupling compounds, and cosmetically acceptable salts thereof, for use with conventional primary intermediate dye compounds and oxidizing agents for the oxidative coloring of human hair. The compositions of the invention may also contain other components typically used in oxidative hair dye preparations to impart intense and lasting coloration to hair.
Type:
Grant
Filed:
November 21, 1997
Date of Patent:
February 2, 1999
Assignee:
Bristol-Myers Squibb Company
Inventors:
Mu-Iii Lim, Yuh-Guo Pan, Linas R. Stasaitis
Abstract: The invention provides fully aqueous-based antiperspirant compositions for application onto the skin for reducing or inhibiting body malodor and perspiration. The compositions contain blocked polyglycols which function as detackifiers and/or emollients, and which provide a completely soluble environment for the antiperspirant active ingredient. The compositions of the invention are stable, are easily and inexpensively prepared and manufactured, and provide versatile formulations which may be delivered and applied to the skin by a variety of means, including roll-ons, aerosols, and the like. Without the need for emulsions or stringent alcohol additives, the aqueous-based antiperspirant solution technology of the invention provides compositions that are clear, non-tacky, quick drying, and leave little to no visible residue or film on the skin following application.
Type:
Grant
Filed:
August 20, 1996
Date of Patent:
November 10, 1998
Assignee:
Bristol-Myers Squibb Company
Inventors:
Leonard Mackles, Mary T. Larkin, Lise Jorgensen, Leonard Chavkin
Abstract: Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
Abstract: The present invention concerns improved processes for dyeing keratinous fibers especially hair on the human scalp using a two-step oxidation process for the oxidation of the melanin precursors 5,6-dihydroxyindoline (DHIN), 5,6-dihydroxyindole (DHI), and derivatives thereof such as 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
Abstract: A cosmetic mask product is disclosed comprising first and second compositions for sequential application to the face of a consumer, one of said composition containing an effervescent agent and the other of said composition containing an acid component.
Abstract: The present invention is directed to the preparation of an aqueous hair dyeing composition containing an effective hair dyeing amount--at least 2 mg/ml--5,6-dihydroxyindole (DHI). An aqueous hair dyeing composition is produced by reacting under essentially anaerobic conditions dopa or a salt thereof with an alkali metal ferricyanide oxidant in an aqueous reaction medium to obtain dopachrome, and permitting the dopachrome to undergo rearrangement in the aqueous medium to form 5,6-dihydroxyindole, said rearrangement being conducted in the substantial absence of oxidant, the aqueous medium being buffered by sufficient buffering agent to maintain a pH of from about 4.5 to about 9 for the reaction medium throughout the series of reactions that take place thereafter, removing the ferrocyanide species present in the aqueous system, and lastly, charging the composition into a suitable container.
Type:
Grant
Filed:
February 16, 1996
Date of Patent:
January 6, 1998
Assignee:
Clairol Incorporated
Inventors:
Giuseppe Prota, Gottfried Wenke, Leszek Wolfram
Abstract: Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
Abstract: The specification describes water soluble, cationic products useful as hair colorants or for skin care obtained by oxidative polymerization of a 5,6-dihydroxyindole-2-quaternary amides or esters, as well as compositions containing the same, methods of using the same in compositions to color hair or treat skin and intermediates for producing the products.
Abstract: A process for altering the color of hair that has been dyed with dihydroxyindole comprising the steps of treating the dyed hair with an acidic solution for an effective amount of time and rinsing the treated hair.
Abstract: A process for dyeing hair by preparing and applying to the hair an aqueous reaction medium comprising a dopa species, a reactive direct dye and an oxidant, said aqueous reaction medium optionally containing at least one hair dyeing agent selected from the group consisting of primary intermediates and couplers and also containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
Abstract: A process of dyeing hair by preparing and applying to the hair an aqueous reaction medium buffered to a pH of from 7 to 11 with a bicarbonate or a TRIS buffer, a catalytic quantity of a cupric or ferrous salt, a catechol and a persulfate oxidizing agent and removing the composition after the desired color is attained, and compositions and kits for practicing such process. The composition may be formed by simultaneous addition of the catechol and the oxidant to the hair or by addition of the catechol followed by addition of the oxidant.
Abstract: A process of dyeing hair by preparing and applying to the hair an aqueous reaction medium comprising an aminoethanethiol, a dihydroxybenzene and a ferricyanide or persulfate oxidizing agent, the composition optionally containing a color modifier selected from the group consisting of direct dyes, primary intermediates, couplers and mixtures thereof, and also containing a buffer to maintain the pH in the range from 2 to 11 during the oxidation reaction, and removing the aqueous reaction medium from the hair after the desired color is attained, and compositions and kits for practicing such processes.
Abstract: The present invention provides for roll-on antiperspirant compositions and more particularly concerns antiperspirant compositions which are clear and, when applied to the human skin, do not leave a visible white residue after drying. The present invention is also particularly concerned with the preparation of clear antiperspirant roll-on compositions which are stable under varying temperature conditions and also provide a suitable cosmetically acceptable feel or sensation when applied to the human skin.
Abstract: A process for preparing dye compositions which comprises hydrolyzing an O-protected 5,6-dihydroxyindole with an alkaline material under anaerobic condition and the products made by such process.
Type:
Grant
Filed:
May 31, 1995
Date of Patent:
May 14, 1996
Assignee:
Clairol Incorporated
Inventors:
Bryan P. Murphy, Keith C. Brown, Thomas M. Schultz, Alice A. Meyer
Abstract: A method and system is described for the noninvasive administration of a therapeutic concentration of a deoxyspergualin compound to a patient comprising iontophoretically passing the deoxyspergualin compound through an area of the skin of the patient at a flux effective to provide the therapeutic concentration.
Type:
Grant
Filed:
February 25, 1994
Date of Patent:
April 9, 1996
Assignee:
Bristol-Myers Squibb Company
Inventors:
Hemanshu S. Shah, Cheng-Der Yu, Mark A. Tepper, Bhiku Patel
Abstract: A process for preparing dye compositions which comprises hydrolyzing an O-protected 5,6-dihydroxyindole with an alkaline material under substantially anaerobic condition and the products made by such process.
Type:
Grant
Filed:
January 5, 1990
Date of Patent:
February 20, 1996
Assignee:
Clairol Incorporated
Inventors:
Bryan P. Murphy, Keith C. Brown, Thomas M. Schultz, Alice A. Meyer
Abstract: The present invention provides for roll-on antiperspirant compositions and more particularly concerns antiperspirant compositions which are clear and, when applied to the human skin, do not leave a visible white residue after drying. The present invention is also particularly concerned with the preparation of clear antiperspirant roll-on compositions which are stable under varying temperature conditions and also provide a suitable cosmetically acceptable feel or sensation when applied to the human skin.
Abstract: A tamper-resistant dosage form capsule for the oral administration of therapeutic agents comprises a two-part capsule which is shrunk around a caplet so that the outer wall of the caplet is bound to the inner walls of both parts of the capsule. The caplet is placed into the capsule, and the dosage form is then subjected to relatively high humidity and temperature conditions, followed by drying the dosage form in a lower humidity environment, so that the capsule is shrunk to conform to the contours of the caplet and both parts of the capsule are bonded to the caplet.
Type:
Grant
Filed:
April 21, 1994
Date of Patent:
October 10, 1995
Assignee:
Bristol-Myers Squibb Company
Inventors:
Mahesh Patell, Gerard Frunzi, F. Henry Merkle, Thomas Tencza
Abstract: A process for increasing the amount of melanin formation following hair dyeing by ferricyanide oxidation of a dopa species hair colorant utilizing a post-oxidant such as sodium periodate at a controlled pH and compositions and kits for use in the process.