Patents Assigned to Amyris, Inc.
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Patent number: 10071034Abstract: Provided herein are compositions comprising partially hydrogenated farnesene. In certain embodiments, the compositions are useful as solvents, degreasers, cleaning products, personal care products, and for other uses. Also provided herein are methods of making the compositions and methods of their use.Type: GrantFiled: May 1, 2015Date of Patent: September 11, 2018Assignee: AMYRIS, INC.Inventors: Ross Keating Eppler, Karl Fisher, Roberto Vazquez
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Patent number: 10041092Abstract: Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. In some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker.Type: GrantFiled: September 9, 2016Date of Patent: August 7, 2018Assignee: AMYRIS, INC.Inventors: Andrew Horwitz, Kristy Michelle Hawkins, Max Schubert, Wayne Szeto
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Patent number: 9994705Abstract: A thermoplastic elastomer composition comprising 100 parts by mass of a hydrogenated block copolymer (A) comprising a polymer block (a) consisting of a structural unit derived from an aromatic vinyl compound and a polymer block (b) comprising 1 to 100% by mass of a structural unit (b1) derived from farnesene and comprising 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, a mass ratio [(a)/(b)] of the polymer block (a) to the polymer block (b) being 1/99 to 70/30; and 5 to 300 parts by mass of a polar group-containing olefinic polymer (B), is excellent in flexibility and molding processability and capable of adhering to a ceramic, a metal, a synthetic resin, or the like even through a heat treatment at low temperatures (for example, 190° C. or lower) without requiring a primer treatment or the like.Type: GrantFiled: December 11, 2014Date of Patent: June 12, 2018Assignees: KURARAY CO., LTD., AMYRIS, INC.Inventors: Yusuke Tanaka, Hiromitsu Sasaki, Shota Suzuki, Yosuke Uehara
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Publication number: 20180155741Abstract: Provided herein is a gaseous isoprene composition comprising isoprene, carbon dioxide and water, wherein the isoprene is in an amount between about 0.1% and about 15% by volume; wherein the carbon dioxide is in an amount between about 0.04% and about 35% by volume; wherein the water is in an amount greater than about 70% of its saturation amount. Also provided herein is a liquid isoprene composition comprising isoprene in an amount of at least 65% by weight and carbon dioxide in an amount between about 0.01% and about 1% by weight.Type: ApplicationFiled: December 21, 2017Publication date: June 7, 2018Applicant: AMYRIS, INC.Inventor: Derek MCPHEE
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Publication number: 20180134890Abstract: A resin composition including a hydrogenated block copolymer (A) including a polymer block (a) consisting of a structural unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a structural unit (b1) derived from farnesene and containing 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, 50 mol % or more of a carbon-carbon double bond in the polymer block (b) being hydrogenated; and at least one resin (B) selected from the group consisting of a polyphenylene ether-based resin, a styrene-based resin, an acrylic resin, a polycarbonate-based resin, and a polyamide-based resin.Type: ApplicationFiled: December 11, 2014Publication date: May 17, 2018Applicants: KURARAY CO., LTD., AMYRIS, INC.Inventors: Yusuke TANAKA, Hiromitsu SASAKI, Yosuke UEHARA, Daisuke KONISHI
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Publication number: 20180134931Abstract: A sealant including a block copolymer comprising a polymer block (a) comprising a structural unit derived from an aromatic vinyl compound and a polymer block (b) comprising 1 to 100% by mass of a structural unit (b1) derived from farnesene and 99 to 0% by mass of a structural unit (b2) derived from a conjugated diene other than farnesene, a mass ratio [(a)/(b)] of the polymer block (a) to the polymer block (b) being 5/95 to 45/55, is excellent in molding processability, flexibility, and adhesiveness and also excellent in sound insulation properties and vibration-damping properties (vibration attenuation properties) in a high frequency region in the neighborhood of 4,000 Hz even under high temperatures.Type: ApplicationFiled: December 11, 2014Publication date: May 17, 2018Applicants: KURARAY CO., LTD., AMYRIS, INC.Inventors: Hiromitsu SASAKI, Yosuke UEHARA
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Patent number: 9914941Abstract: Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids.Type: GrantFiled: September 2, 2014Date of Patent: March 13, 2018Assignee: AMYRIS, INC.Inventors: Timothy Stevens Gardner, Kristy Michelle Hawkins, Adam Leon Meadows, Annie Ening Tsong, Yoseph Tsegaye
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Patent number: 9885061Abstract: Provided herein is a gaseous isoprene composition comprising isoprene, carbon dioxide and water, wherein the isoprene is in an amount between about 0.1% and about 15% by volume; wherein the carbon dioxide is in an amount between about 0.04% and about 35% by volume; wherein the water is in an amount greater than about 70% of its saturation amount. Also provided herein is a liquid isoprene composition comprising isoprene in an amount of at least 65% by weight and carbon dioxide in an amount between about 0.01% and about 1% by weight.Type: GrantFiled: December 2, 2015Date of Patent: February 6, 2018Assignee: AMYRIS, INC.Inventor: Derek McPhee
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Preparation of homoallylic compounds by reaction of cyclopropylvinyl precursors with bronstedt acids
Patent number: 9884803Abstract: A method of forming homoallylic compounds 2 from cyclopropylvinyl precursors 1 in the presence of a Bronsted acid HQType: GrantFiled: October 24, 2014Date of Patent: February 6, 2018Assignees: Givaudan SA, Amyris, Inc.Inventor: Fridtjof Schroeder -
Publication number: 20180030194Abstract: A hydrogenated block copolymer prepared by hydrogenating a block copolymer that contains a polymer block (A) containing a structural unit derived from an aromatic vinyl compound, a polymer block (B) containing a structural unit derived from farnesene, and a polymer block (C) containing a structural unit derived from a conjugated, diene except farnesene, wherein the block copolymer contains at least two above polymer blocks (A), at least one above polymer block (B) and at least one above polymer block (C), and wherein at least one above polymer block (B) is at the terminal, and the hydrogenation rate of the carbon-carbon double bond in the polymer block (B) and the polymer block (C) is 50 mol % or more.Type: ApplicationFiled: February 5, 2016Publication date: February 1, 2018Applicants: KURARAY CO., LTD., AMYRIS, INC.Inventors: Yosuke UEHARA, Hiromitsu SASAKI, Daisuke KONISHI, Masahiro KATO
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Patent number: 9862906Abstract: Provided herein are isoparaffins derived from hydrocarbon terpenes such as myrcene, ocimene and farnesene, and methods for making the same. In certain variations, the isoparaffins have utility as lubricant base stocks.Type: GrantFiled: February 13, 2012Date of Patent: January 9, 2018Assignee: AMYRIS, INC.Inventors: Nicholas Ohler, Karl Fisher, Shakeel Tirmizi
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Patent number: 9850336Abstract: The present invention relates to a copolymer including a monomer unit (a) derived from a conjugated diene having not more than 12 carbon atoms and a monomer unit (b) derived from farnesene; a process for producing the copolymer including at least the step of copolymerizing a conjugated diene having not more than 12 carbon atoms with farnesene; a rubber composition including (A) the copolymer, (B) a rubber component and (C) carbon black; a rubber composition including (A) the copolymer, (B) a rubber component and (D) silica; a rubber composition including (A) the copolymer, (B) a rubber component, (C) carbon black and (D) silica; and a tire using the rubber composition at least as a part thereof.Type: GrantFiled: April 2, 2013Date of Patent: December 26, 2017Assignees: KURARAY Co., Ltd., AMYRIS, INC.Inventors: Daisuke Koda, Kei Hirata
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Patent number: 9834666Abstract: Provided is a polyolefin-based resin composition including a hydrogenated block copolymer (A) and a polyolefin-based resin (B), the hydrogenated block copolymer (A) being a hydrogenated product of a block copolymer including a polymer block (a) composed of a constitutional unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a constitutional unit (b1) derived from farnesene and 99 to 0% by mass of a constitutional unit (b2) derived from a conjugated diene other than farnesene; a mass ratio of the polymer block (a) and the polymer block (b) [(a)/(b)] being 1/99 to 55/45; 50 mol % or more of carbon-carbon double bonds in the polymer block (b) being hydrogenated; and a mass ratio of the polyolefin-based resin (B) and the hydrogenated block copolymer (A) [{polyolefin-based resin (B)}/{hydrogenated block copolymer (A)}] being 1/99 to 99/1.Type: GrantFiled: September 29, 2014Date of Patent: December 5, 2017Assignees: KURARAY CO., LTD., AMYRIS, INC.Inventors: Hiromitsu Sasaki, Yosuke Uehara, Shota Suzuki
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Publication number: 20170327681Abstract: The present invention provides a sealing material composition including 100 parts by mass of a polymer of farnesene (A) and from 1 to 4,000 parts by mass of a filler (B).Type: ApplicationFiled: October 27, 2015Publication date: November 16, 2017Applicants: KURARAY CO., LTD., AMYRIS, INC.Inventors: Hiroshi KANBARA, Kei HIRATA
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Publication number: 20170283342Abstract: A process of converting a carbon-carbon multiple bond to a cyclopropane ring, comprising the addition of a N-alkyl-N-nitroso compound to a mixture of alkene precursor, aqueous base and Pd(II)-catalyst, with the N-alkyl-N-nitroso compound obtained directly from an alkyl amine derivative, NaNO2 and an acid via phase separation of the N-alkyl-N-nitroso compound from the aqueous phase.Type: ApplicationFiled: June 22, 2017Publication date: October 5, 2017Applicants: Givaudan, S.A., Amyris Inc.Inventors: Fridtjof SCHRÖDER, Fabian RUETHI
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Patent number: 9765363Abstract: A system and method for producing bio-organic compounds may include a vessel, a first phase comprising an aqueous medium including host cells capable of producing a bio-organic compound, where the bio-organic compound comprises a second phase in contact with the aqueous medium.Type: GrantFiled: May 25, 2007Date of Patent: September 19, 2017Assignee: Amyris, Inc.Inventor: Neil Stephen Renninger
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Publication number: 20170260374Abstract: The present invention relates to a copolymer including a monomer unit (a) derived from isoprene and a monomer unit (b) derived from farnesene; a process for producing the copolymer including at least the step of copolymerizing isoprene with farnesene; a rubber composition including (A) the copolymer, (B) a rubber component and (C) carbon black; a rubber composition including (A) the copolymer, (B) a rubber component and (D) silica; a rubber composition including (A) the copolymer, (B) a rubber component, (C) carbon black and (D) silica; and a tire using the rubber composition at least as a part thereof.Type: ApplicationFiled: May 24, 2017Publication date: September 14, 2017Applicants: KURARAY CO., LTD., AMYRIS, INC.Inventors: Daisuke KODA, Kei Hirata
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Patent number: 9752027Abstract: The thermoplastic elastomer composition of the present invention is a thermoplastic elastomer composition including a hydrogenated block copolymer (A) and a softening agent (B), the hydrogenated block copolymer (A) being a hydrogenated product of a block copolymer including a polymer block (a) composed of a constitutional unit derived from an aromatic vinyl compound and a polymer block (b) containing 1 to 100% by mass of a constitutional unit (b1) derived from farnesene and 99 to 0% by mass of a constitutional unit (b2) derived from a conjugated diene other than farnesene; a mass ratio of the polymer block (a) and the polymer block (b) [(a)/(b)] being 1/99 to 70/30; 50 mol % or more of carbon-carbon double bonds in the polymer block (b) being hydrogenated; and a content of the softening agent (B) being 20 to 2,000 parts by mass on the basis of 100 parts by mass of the hydrogenated block copolymer (A).Type: GrantFiled: September 29, 2014Date of Patent: September 5, 2017Assignees: KURARAY CO., LTD., AMYRIS, INC.Inventors: Hiromitsu Sasaki, Yosuke Uehara, Masahiro Kato
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Publication number: 20170240923Abstract: Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, and a nuclease capable of causing a double-strand break near or within the genomic target site.Type: ApplicationFiled: February 3, 2017Publication date: August 24, 2017Applicant: Amyris, Inc.Inventors: Zach Serber, Andrew Horwitz
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Patent number: 9732206Abstract: The present invention relates to a copolymer including a monomer unit (a) derived from isoprene and a monomer unit (b) derived from farnesene; a process for producing the copolymer including at least the step of copolymerizing isoprene with farnesene; a rubber composition including (A) the copolymer, (B) a rubber component and (C) carbon black; a rubber composition including (A) the copolymer, (B) a rubber component and (D) silica; a rubber composition including (A) the copolymer, (B) a rubber component, (C) carbon black and (D) silica; and a tire using the rubber composition at least as a part thereof.Type: GrantFiled: April 2, 2013Date of Patent: August 15, 2017Assignees: KURARAY CO., LTD., AMYRIS, INC.Inventors: Daisuke Koda, Kei Hirata