Patents Assigned to Lexicon
  • Human dectin proteins and polynucleotides encoding the same
    Patent number: 7252990
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: August 7, 2007
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Emily B. Cullinan
  • Human GABA transporter protein and polynucleotides encoding the same
    Patent number: 7229790
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: June 12, 2007
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Carl Johan Friddle, Brenda Gerhardt, Yi Hu
  • Human semaphorin homologs and polynucleotides encoding the same
    Patent number: 7199221
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: April 3, 2007
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Xiaoming Wang, John Scoville, C. Alexander Turner, Jr.
  • Thiazoles and methods of their use
    Patent number: 7179827
    Abstract: This invention concerns novel thiazole compounds. Methods of using these compounds for the treatment, prevention and management of various diseases or disorders, as well as pharmaceutical compositions of these compounds, are also disclosed.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: February 20, 2007
    Assignee: Lexicon Genetics Incorporated
    Inventors: Haihong Jin, Zhi-Cai Shi, Heidi Theis, Hartmuth Kolb
  • Lipoxygenase proteins and polynucleotides encoding the same
    Patent number: 7144730
    Abstract: The nucleotide and corresponding amino acid sequences are reported for a novel class of mammalian lipoxygenase proteins. The novel lipoxygenase encoding polynucleotides were obtained from human gene trap clones and human cDNA libraries.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: December 5, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Zambrowicz, Michael Nehls, Glenn Friedrich, Arthur T. Sands
  • Human hydroxylases and polynucleotides encoding the same
    Patent number: 7105325
    Abstract: Noval human polynucleotide and polypeptide sequences are disclosed that can be used in industrial, therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: September 12, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, Maricar Miranda, Yi Hu
  • Polynucleotides encoding human GABA receptors
    Patent number: 7074591
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: July 11, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Carl Johan Friddle, Brian Mathur, C. Alexander Turner, Jr.
  • Human ion-exchanger proteins
    Patent number: 7057029
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: June 6, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: Carl Johan Friddle, Brenda Gerhardt
  • Human semaphorin proteins and polynucleotides encoding the same
    Patent number: 7001763
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: February 21, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, John Scoville
  • Human synaptotagmin and polynucleotides encoding the same
    Patent number: 6994995
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: February 7, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy
  • Human uncoupling proteins and polynucleotides encoding the same
    Patent number: 6987178
    Abstract: The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described uncoupling proteins (UCPs).
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: January 17, 2006
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Brian Zambrowicz, Arthur T. Sands
  • Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates
    Patent number: 6951946
    Abstract: Disclosed are efficient and scalable processes for preparing 1,2,4- and 1,3,4-oxadiazole carboxylates from readily available starting materials.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: October 4, 2005
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hartmuth C. Kolb, Ramanaiah C. Kanamarlapudi, Paul F. Richardson
  • Human transferase proteins and polynucleotides encoding the same
    Patent number: 6929937
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: August 16, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands, D. Wade Walke, Nathaniel L. Wilganowski
  • Human kinases and polynucleotides encoding the same
    Patent number: 6919192
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: July 19, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Carl Johan Friddle
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6908758
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: June 21, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy, Xiaoming Wang, Gregory Donoho, John Scoville, D. Wade Walke
  • Human kinases and polynucleotides encoding the same
    Patent number: 6902924
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: June 7, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Carl Johan Friddle
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6902923
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: June 7, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, John Scoville, Gregory Donoho, C. Alexander Turner, Jr., Brian Mathur, Daniel Mathur, Carl Johan Friddle
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6900045
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: May 31, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Carl Johan Friddle, Erin Hilbun, Boris Nepomnichy, Yi Hu
  • Human ATPase proteins and polynucleotides encoding the same
    Patent number: 6900046
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: May 31, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Erin Hilbun, Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Water as promoter in the nucleophilic substitution of chloride
    Patent number: 6891068
    Abstract: Disclosed is a one step method for preparing a ?-substituted sulfide by treating a ?-halosulfide with a nucleophile in water.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: May 10, 2005
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hartmuth C. Kolb, Zhi-Cai Shi, Zhi-Min Wang