Patents Assigned to Lexicon
  • Vectors for gene mutagenesis and gene discovery
    Patent number: 6808921
    Abstract: Novel vectors are described that incorporate, inter alia, a novel 3′ gene trap cassette that does not encode a marker conferring antibiotic resistance and which can be used to efficiently trap, mutagenize, and identify previously unknown cellular genes. Vectors incorporating the presently described 3′ gene trap cassette find particular application in gene discovery, and the production of mutated cells and animals.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: October 26, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Brian Zambrowicz, Glenn A. Friedrich, Stan Lilleberg, Arthur T. Sands
  • Human LDL receptor encoding polynucleotides
    Patent number: 6806083
    Abstract: The present invention relates to LDLPs, nucleotides encoding the same, and methods and compositions for the treatment of biological disorders regulatable by the controlled expression, binding, and/or inhibition of the described LDLPs.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: October 19, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Zambrowicz, Glenn Friedrich, Arthur T. Sands
  • Modified safe and efficient process for the environmentally friendly synthesis of imidoesters
    Patent number: 6806380
    Abstract: Disclosed is a safe, efficient and environmentally friendly method for preparing imidoesters.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: October 19, 2004
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hartmuth C. Kolb, Ramanaiah C. Kanamarlapudi, Paul F. Richardson, Gaznabi Khan
  • Human kinase proteins and polynucleotides encoding the same
    Patent number: 6806073
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: October 19, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Jr., Glenn Friedrich, Brian Zambrowicz, Alejandro Abuin, Arthur T. Sands
  • Human kinase and polynucleotides encoding the same
    Patent number: 6803221
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: October 12, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, James Alvin Kieke, Gregory Donoho
  • Human kinases and polynucleotides encoding the same
    Patent number: 6797510
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: September 28, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, John Scoville, Carl Johan Friddle
  • Human mitochondrial proteins and polynucleotides encoding the same
    Patent number: 6790667
    Abstract: The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described NHP.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: September 14, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Erin Hilbun, David George Potter
  • Human kielin-like proteins and polynucleotides encoding the same
    Patent number: 6790660
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: September 14, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, John Scoville, Nathaniel L. Wilganowski, Nghi D. Nguyen
  • Polynucleotides encoding human ion-exchanger proteins
    Patent number: 6787352
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: September 7, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Carl Johan Friddle, Brenda Gerhardt
  • Human carboxypeptidases and polynucleotides encoding the same
    Patent number: 6780640
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: August 24, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human membrane proteins and polynucleotides encoding the same
    Patent number: 6777232
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: August 17, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, John Scoville
  • Vectors for gene mutagenesis and gene discovery
    Patent number: 6776988
    Abstract: Novel vectors are described that incorporate, inter alia, a novel 3′ gene trap cassette which can be used to efficiently trap and identify previously unknown cellular genes. Vectors incorporating the described 3′ gene trap cassette find particular application in gene discovery and in the production of mutated cells and animals.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: August 17, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Brian Zambrowicz, Glenn A. Friedrich, Stan Lilleberg, Arthur T. Sands
  • Human proteases and polynucleotides encoding the same
    Patent number: 6777221
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: August 17, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, Erin Hilbun, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human kinases and polynucleotides encoding the same
    Patent number: 6777545
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: August 17, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Brian Mathur, Carl Johan Friddle
  • Human kinase and polynucleotides encoding the same
    Patent number: 6773906
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: August 10, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, Boris Nepomnichy, Brenda Gerhardt, D. Wade Walke, Carl Johan Friddle
  • Human ion channel protein and polynucleotides encoding the same
    Patent number: 6767736
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: July 27, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Yi Hu, James Alvin Kieke, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human kinase and polynucleotides encoding the same
    Patent number: 6759527
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: July 6, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Xuanchuan Yu, Maricar Miranda
  • Human semaphorin homologs and polynucleotides encoding the same
    Patent number: 6750054
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic application.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: June 15, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: D. Wade Walke, Xiaoming Wang, John Scoville, C. Alexander Turner, Jr.
  • Human kinase protein and polynucleotides encoding the same
    Patent number: 6746861
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: June 8, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, Erin Hilbun, C. Alexander Turner, Jr., Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands
  • Human proteins and polynucleotides encoding the same
    Patent number: 6743907
    Abstract: Novel human CUB domain containing protein polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: June 1, 2004
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, C. Alexander Turner, Jr., Michael C. Nehls, Glenn Friedrich, Brian Zambrowicz, Arthur T. Sands