Abstract: An analysis unit 111 for automatically analyzing a sample comprises a sample dispensing nozzle 2 for dispensing the sample and an electrolyte measurement unit 114 for carrying out internal standard liquid measurement one or more times at least before measuring the electric potential of the sample. If the electrolyte measurement unit 114 is to carry out the electric potential measurement of the sample in succession, a different internal standard liquid measurement operation is carried out before the electric potential measurement than if the electric potential measurement is not to be carried out in succession and there are to be gaps between measurement intervals. This results in the provision of an automated analyzer, automatic analysis system, and automatic sample analysis method that make it possible to reduce the influence of ambient temperature on electrolyte measurement, ensure measurement accuracy, and enhance overall device processing capacity.

Abstract: The disclosure relates to a device for dielectrophoretic capture of particles. The device includes at least one electrical contact and at least one layer. The at least one layer includes a top layer side, a bottom layer side, and a barrier structure. The barrier structure is configured such that a fluid comprising the particles can flow through the barrier structure which is disposed on the top layer side. The barrier structure spaces the top layer side apart from the bottom layer side of at least one of the same layer and a second of the at least one layer.

Abstract: A single molecule sensing or detecting device includes a first electrode and a second electrode separated from the first electrode by a gap. The first electrode and the second electrode have an opening formed therethrough. At least one of the first electrode and the second electrode is functionalized with a recognition molecule. The recognition molecule has an effective length LI and is configured to selectively bind to a target molecule having an effective length L2. The size of the gap is configured to be greater than L2, but less than or equal to the sum of LI and L2.

Abstract: A method for monitoring mechanochemical activation of metal powders in dynamic electrochemical environment and a device thereof are provided. The method includes constructing a dynamic testing environment in an electrochemical cell, using a three-electrode system, and collecting data from an external electrochemical workstation. The three-electrode system is composed of the working metal plate, the reference electrode, and the platinum electrode. The dynamic testing environment includes small load impacts and changes in pH and composition of the solution. Under the premise of simulating the production environment of the mechanical plating and the water-based metal coating material, the monitoring method described in the present disclosure cooperates with an electrochemical workstation for OCPT testing to achieve the monitoring of mechanochemical activation of metal powders in dynamic electrochemical environment.

Abstract: The present invention forms a detection layer in an embedded biosensor probe by using a phenazine derivative as a redox mediator in which a phenazine group is covalently bonded to a high molecular weight polymer having a carboxyl group or an amino group, such as polyamino acid, polyimine, or polyallylamine; and the distance between the phenazine group and the high molecular weight polymer main chain is increased by using a polyethylene glycol chain.

Abstract: In a gas sensor, oxygen pumping control is performed to pump oxygen from the surroundings of an outer side pump electrode into the surroundings of a reference electrode. In addition, during execution of the oxygen pumping control, a pump current Ip2 is measured when oxygen originating from NOx is pumped out from the surroundings of a measurement electrode so that a voltage V2 reaches a target voltage V2*. Then, the NOx concentration of a measurement-object gas is calculated based on Ip2. In the gas sensor, the NOx concentration is corrected based on DVref which is the difference between Vref1 and Vref2, wherein Vref1 is the voltage across the reference electrode and the outer side pump electrode when the oxygen pumping control is not performed, and Vref2 is the voltage across the reference electrode and the outer side pump electrode when the oxygen pumping control is performed.

Abstract: In a method for sensing translocation of a molecule through a nanopore, a molecule in a first fluidic solution in a first fluidic reservoir that is in direct fluidic connection with the nanopore is directed to a nanopore inlet and translocated through the nanopore to a nanopore outlet and through a fluidic passage that is in direct fluidic connection with the nanopore outlet, to a second fluidic solution in a second fluidic reservoir disposed in direct fluidic connection with the fluidic passage. The fluidic passage has at least one fluidic section in which a length of the fluidic section is greater than a width of the fluidic section. Translocation of the molecule through the nanopore is sensed by measuring the electrical potential local to the fluidic passage during the translocation of the molecule.

Abstract: An embodiment provides a method for measuring an analyte of a sample, including: introducing a sample to a sample region of a measurement device; the measurement device comprising: a measurement electrode and a ground electrode contacting the sample; a low-slope reference electrode in a reference electrode assembly having an electrolyte solution, wherein the electrolyte solution is in contact with the low-slope reference electrode; wherein the electrolyte solution is electrically coupled to the sample via at least one junction; and measuring a first potential between the measurement electrode and the ground electrode; measuring a second potential between the low-slope reference electrode and the ground electrode; determining an analyte in the sample by comparing the first potential and the second potential. Other aspects are described and claimed.

Abstract: A method of forming a glass electrochemical sensor is described. In some embodiments, the method may include forming a plurality of electrical through glass vias (TGVs) in an electrode substrate; filling each of the plurality of electrical TGVs with an electrode material; forming a plurality of contact TGVs in the electrode substrate; filling each of the plurality of contact TGVs with a conductive material; patterning the conductive material to connect the electrical TGVs with the contact TGVs; forming a cavity in a first glass layer; and bonding a first side of the first glass layer to the electrode substrate.

Abstract: To provide a zeta-potential measurement jig which does not require dedicated tools and enables placement of a sample in a cell with simple work. Provided is a zeta-potential measurement jig, to be used for an electrophoretic mobility measuring device, including: a frame body including: a first holding wall and a second holding wall; and a bottom wall; an intermediate block, and a cell retainer, wherein at least one of the first holding wall or the second holding wall has one of a first groove or a first protrusion to be elastically fitted into the first groove, which is configured to support the intermediate block on a lateral side, and wherein the intermediate block has another one of the first groove or the first protrusion.

Abstract: In a nanopore sensor, a nanopore disposed in a support structure has a nanopore diameter and nanopore resistance, RPore. A fluidic passage, disposed in fluidic connection between a first fluidic reservoir and the nanopore, has a cross-sectional extent, along at least a portion of the fluidic passage length, that is greater than the diameter of the nanopore and that is less than the fluidic passage length. The fluidic passage has a fluidic passage resistance, RFP, of at least about 10% of the nanopore resistance, RPore, and no more than about 10 times the nanopore resistance, RPore. The nanopore is disposed in fluidic connection between the fluidic passage and a second fluidic reservoir. At least one electrical transduction element is disposed at the fluidic passage and electrically connected to produce an indication of electrical potential local to the fluidic passage.

Abstract: The present disclosure discloses an electroanalytical sensor for the detection of meloxicam. The electroanalytical sensor comprises a carbon electrode. The carbon electrode comprises zinc oxide (ZnO) nanoparticles, wherein the ZnO nanoparticles are co-doped with silver (Ag) and cobalt (Co). The present disclosure also discloses a method of detecting meloxicam using an electroanalytical sensor. The electroanalytical sensor comprises a carbon electrode, the carbon electrode comprising zinc oxide (ZnO) nanoparticles co-doped with silver (Ag) and cobalt (Co). The method of detecting meloxicam comprises the step of positioning a liquid droplet, comprising solvent, to be tested on a surface of the electrode. The method further comprises receiving a voltammetric response from the electrode, and analysing the voltammetric response to determine if meloxicam is present in the liquid droplet.

Abstract: An electrochemical measurement method is provided in which a working electrode that causes an oxidation-reduction reaction with a measurement target and a counter electrode connected to the working electrode are provided in an electrolytic solution containing the measurement target, and a measuring voltage is applied between the working electrode and the counter electrode to measure a current that flows between the working electrode and the counter electrode in proportion to the amount of the measurement target, wherein an eliminating electrode is provided in the electrolytic solution, and the method performs: eliminating the measurement target by applying an eliminating voltage, which has the same polarity as the measuring voltage, between the eliminating electrode and the counter electrode to oxidize or reduce the measurement target; diffusing a new measurement target; and measuring the current by applying the measuring voltage between the working electrode and the counter electrode.

Abstract: The invention relates to a solid electrolyte comprised of partially stabilized zirconia, and a gas sensor including the solid electrolyte. The partially stabilized zirconia includes crystal particles, the crystal particles include at least stabilizer low-concentration phase particles, and the partially stabilized zirconia further includes voids. Among the stabilizer low-concentration phase particles, the presence rate of the stabilizer low-concentration phase particles where each distance from a void is 5 ?m or less is 65 volume percent or more. The stabilizer low-concentration phase particles include specific stabilizer low-concentration phase particles each having a distance of 5 ?m or less from an adjacent void in the voids, a presence rate of the specific stabilizer low-concentration phase particles having 65 volume percent or more.

Abstract: An all-electronic high-throughput detection system can perform multiple detections of one or more analyte in parallel. The detection system is modular, and can be easily integrated with existing microtiter plate technologies, automated test equipments and lab workflows (e.g., sample handling/distribution systems). The detection system includes multiple sensing modules that can perform separate analyte detection. A sensing module includes a platform configured to couple to a sample well. The sensing module also includes a sensor coupled to the platform. The sensing module further includes a first electrode coupled to the platform. The first electrode is configured to electrically connect with the sensor via a feedback circuit. The feedback circuit is configured to provide a feedback signal via the first electrode to a sample received in the sample well, the feedback signal based on a potential of the received sample detected via a second electrode.

Abstract: A measuring device 1 according to the present disclosure measures a state of a solution L. The measuring device 1 includes a measuring unit 10 that outputs a measurement signal associated with the state of the solution L, a protection unit 20 attached to the measuring unit 10, and a controller 40 that obtains the information on the state of the solution L on the basis of a measurement signal output from the measuring unit 10. The measuring unit 10 has a first part P1 in a usable state that contributes to output of the measurement signal by coming into contact with the solution L, and a second part that is isolated from the solution L by the protection unit 20 and is in a standby state for measurement.

Abstract: Embodiments described herein generally relate to cartridges suitable for performing electrophoretic separation of analytes. Cartridges described herein are particularly well suited for reuse. Cartridges described herein can include a reservoir disposed between a capillary and a container containing a run buffer. The reservoir can inhibit run buffer from intruding into the capillary, thereby allowing repeated electrophoretic separations to be more consistent, more accurate, and/or more reliable.

Abstract: Described herein are digital microfluidic (DMF) devices and corresponding methods for managing reagent solution evaporation during a reaction. Reactions on the DMF devices described here are performed in an air or gas matrix. The DMF devices include a means for performing reactions at different temperatures. To address the issue of evaporation of the reaction droplet especially when the reaction is performed at higher temperatures, a means for introducing a replenishing droplet has been incorporated into the DMF device. A replenishing droplet is introduced every time when it has been determined that the reaction droplet has fallen below a threshold volume. Detection and monitoring of the reaction droplet may be through visual, optical, fluorescence, colorimetric, and/or electrical means.

Abstract: A method of detecting a lipid bilayer formed in a cell of a nanopore based sequencing chip is disclosed. An integrating capacitor is coupled with a lipid membrane, wherein the lipid membrane is between a working electrode and a counter electrode. An alternating current (AC) voltage is applied to the counter electrode. A voltage across the integrating capacitor is periodically sampled by an analog-to-digital converter (ADC). A change in the sampled voltage across the integrating capacitor in response to a change in the AC voltage is determined. Whether the lipid membrane comprises a lipid bilayer is detected based on the determined change in the sampled voltage across the integrating capacitor in response to the change in the AC voltage.

Abstract: A potentiometric cell capable of selectively measuring potassium comprising an ion-selective working electrode composition prepared from a carrier solvent composition comprising between 1.5 and 2.4 mg of Valinomycin, between 0.4 and 0.6 mg of potassium Tetrakis (4-chlorophenyl) borate (KTFPB), between 52.48 and 78.72 mg of Poly(vinylchloride) (PVC), and between 103.52 and 155.28 mg of Bis(2-ethylhexyl) sebacate (DOS) per ml of the carrier solvent in combination with a specially adapted reference electrode. The cell exhibits improved precision in potassium ion determinations and high selectivity for potassium ions over other cations in a sample specimen such as whole blood or saliva. The electrode compositions exhibits improved properties over a long period of time and therefore has greater shelf life.