Patents Examined by Alexander S Noguerola
-
Patent number: 11604159Abstract: A electrochemical sensor (100) for sensing an analyte in an associated volume (106), the sensor comprising a first solid element (126), a second solid element (128) being joined to the first solid element, a chamber (110) being placed at least partially between the first solid element and the second solid element, a working electrode (104) in the chamber (110) and wherein one or more analyte permeable openings (122) connect the chamber with the associated volume (106) and wherein the electrochemical sensor (100) further comprises an analyte permeable membrane (124) in said one or more analyte permeable openings, and wherein the one or more analyte permeable openings are arranged so that a distance from any point in at least one cross-sectional plane to the nearest point of a wall of said opening is 25 micrometer or less.Type: GrantFiled: July 14, 2017Date of Patent: March 14, 2023Assignee: SulfiLogger A/SInventors: Søren Porsgaard, Lars Hauer Larsen
-
Patent number: 11604160Abstract: A gas sensor includes a sensor element, and the sensor element includes a bottomed tubular solid electrolyte, a detection electrode provided on an outer surface of the solid electrolyte, a reference electrode provided on an inner surface of the solid electrolyte. The detection electrode of the sensor element includes a detection electrode section provided at a position on a tip side of an axial direction, an attachment electrode section provided at a position on a base end side of the axial direction, and a lead electrode section provided at a position where the detection electrode section is connected to the attachment electrode section. An insulating layer is provided between a tube of the solid electrolyte and each of the attachment electrode section and the lead electrode section.Type: GrantFiled: October 18, 2019Date of Patent: March 14, 2023Assignee: DENSO CORPORATIONInventors: Makoto Nakae, Shota Imada
-
Patent number: 11598745Abstract: Various example embodiments described herein relate to an electrochemical gas sensor. The electrochemical gas sensor can include a sensor cap having one or more solid features disposed on a surface of the sensor cap. The electrochemical gas sensor can include a counter electrode configured to generate a gas during use of the electrochemical gas sensor. The electrochemical gas sensor can include a vent assembly adapted to release at least a portion of the gas generated at the counter electrode out from the electrochemical gas sensor. The vent assembly can include a vent conduit and a vent membrane that defines a passage for the gas to flow from an extended portion of the counter electrode, to the vent conduit, via the vent membrane, so as to be vented from the electrochemical gas sensor.Type: GrantFiled: December 17, 2019Date of Patent: March 7, 2023Assignee: HONEYWELL INTERNATIONAL INC.Inventors: Johnny Jian, Neils Hansen, Keith Francis Edwin Pratt, Paul Westmarland, Fuxia Liu
-
Patent number: 11592417Abstract: Flexible fuel cell sensors and methods of making and using the same are provided. A fuel cell sensor can be used for the detection of, for example, isopropyl alcohol (IPA), and the working mechanism of the fuel cell sensor can rely on redox reactions. The fuel cell sensor can include a proton exchange membrane (PEM), an anode disposed on a first surface of the PEM, a cathode disposed on a second surface of the PEM opposite from the first surface, and a reference electrode disposed on the first surface of the PEM and spaced apart from the anode.Type: GrantFiled: April 27, 2022Date of Patent: February 28, 2023Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEESInventors: Ahmed Hasnain Jalal, Arif I. Sarwat
-
Patent number: 11592420Abstract: Closed-loop systems and methods for controlling pH. The system includes a working electrode, a counter electrode, a reference electrode, a first ion-sensitive field-effect transistor (ISFET), a second ISFET, and an electronic controller. The working electrode, the counter electrode, the reference electrode, and a first sensing terminal of the first ISFET are immersible in an active solution. A second sensing terminal of the second ISFET is immersible in a reference solution. The electronic controller is configured to apply a first amount of current or voltage to the working electrode and determine a differential voltage between the first ISFET and the second ISFET. The electronic controller is also configured to set a second amount of current or voltage to reduce a difference between the differential voltage and a target voltage. The electronic controller is further configured to apply the second amount of current or voltage to the working electrode.Type: GrantFiled: July 17, 2020Date of Patent: February 28, 2023Assignee: ROBERT BOSCH GMBHInventors: Young Shik Shin, Nadezda Fomina, Christopher Johnson, Armin Darvish, Efthymios Papageorgiou, Christoph Lang
-
Patent number: 11592414Abstract: Electrochemical sensors useful for detection of heavy metals are described. The electrochemical sensors can be made by forming a layer of graphene oxide on a working electrode, forming a layer of carbon nanotubes (CNTs) on the layer of graphene oxide, and forming a layer of gold nanostars on the layer of CNTs.Type: GrantFiled: February 27, 2019Date of Patent: February 28, 2023Assignee: University of MassachusettsInventors: Pradeep Unnikrishnan Kurup, Susom Dutta
-
Patent number: 11585809Abstract: Multi-use biosensors are disclosed that include enzymes coupled to nanobeads; the multi-use biosensors are used to detect analytes in fluidic biological samples, and the biosensors also maintain their enzyme activity after many uses. Multi-sensor arrays are disclosed that include multiple biosensors. Also disclosed are methods of producing and using these devices.Type: GrantFiled: February 28, 2018Date of Patent: February 21, 2023Assignee: Siemens Healthcare Diagnostics Inc.Inventor: Michael S. Wilson
-
Patent number: 11585779Abstract: A biosensor, including a modified gold electrode and a macrophage RAW264.7 immobilized on the modified gold electrode. The disclosure also provides a method of preparing the biosensor and a method of using the same for evaluation of antioxidant capacity of substances.Type: GrantFiled: November 19, 2019Date of Patent: February 21, 2023Assignee: NANJING AGRICULTURAL UNIVERSITYInventors: Wangang Zhang, Qingfeng Ge, Donglei Jiang, Panwei Ge, Guanghong Zhou
-
Patent number: 11584909Abstract: The present disclosure relates to a cell potential detection device, a method of manufacturing the cell potential detection device, and an information processing system that enable prevention of culture solution for a cell from leaking. The cell potential detection device includes: a cell potential detection chip including an electrode unit that detects potential of a cell; a substrate on which the cell potential detection chip is implemented; a first member sealing a connection electrically connecting the cell potential detection chip and the substrate; and a second member layered on the first member, the second member forming a liquid-storage portion that stores culture solution for the cell, together with the first member. The present technology can be applied to, for example, a semiconductor module in which packaged is a chip that detects the potential at an action-potential source point due to a chemical change of a cell.Type: GrantFiled: September 21, 2018Date of Patent: February 21, 2023Assignee: SONY SEMICONDUCTOR SOLUTIONS CORPORATIONInventor: Masataka Maehara
-
Patent number: 11573194Abstract: Reference electrodes that include a solid electron conductor; an interlayer; and a polymeric membrane layer comprising a polymer composition, the polymer composition comprising at least one silicone-containing polymer and at least one ionic liquid, wherein the polymeric membrane layer and the polymer composition are essentially plasticizer free and the silicone-containing polymer and the ionic liquid are miscible as determined using a thermodynamic method that shows a single glass transition temperature (Tg) of a composition including the at least one silicone-containing polymer and the at least one ionic liquid, wherein the interlayer is disposed between the solid electron conductor and the polymeric membrane layer. Also disclosed are electrochemical measurement systems including such reference electrodes.Type: GrantFiled: November 11, 2020Date of Patent: February 7, 2023Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Xin Chen, Andreas Stein, Philippe Buhlmann
-
Patent number: 11567036Abstract: Various cell analysis systems of the present teachings can measure the electrical and metabolic activity of single, living cells with subcellular addressability and simultaneous data acquisition for between about 10 cells to about 500,000 cells in a single analysis. Various sensor array devices of the present teachings can have sensor arrays with between 20 million to 660 million ChemFET sensors built into a massively paralleled array and can provide for simultaneous measurement of cells with data acquisition rates in the kilohertz (kHz) range. As various ChemFET sensor arrays of the present teachings can detect chemical analytes as well detect changes in cell membrane potential, various cell analysis systems of the present teachings also provide for the controlled chemical and electrical interrogation of cells.Type: GrantFiled: September 11, 2019Date of Patent: January 31, 2023Assignee: Life Technologies CorporationInventors: Wolfgang Hinz, John Donohue, Daniel Beacham
-
Patent number: 11561193Abstract: A surface modified electrode is provided. The surface modified electrode includes a glassy carbon electrode (GCE) and a nanomaterial disposed on the glassy carbon electrode. The nanomaterial comprises carbon nanotubes (CNTs), and at least one of thallium oxide nanoparticles (Tl2O3.NPs), thallium oxide (Tl2O3) nanopowder, and thallium oxide carbon nanotube nanocomposites (Tl2O3.CNT NCs). A polymer matrix is configured to bind the glassy carbon electrode with the nanomaterial. A method of preparing the surface modified electrode is also disclosed. The surface modified electrode can be implemented in a biosensor for detecting a biological molecule, like choline.Type: GrantFiled: May 27, 2022Date of Patent: January 24, 2023Assignee: King Abdulaziz UniversityInventors: Abdullah Mohamed Asiri, Mohammed Muzibur Rahman, Mohammad Musarraf Hussain
-
Patent number: 11555798Abstract: Methods and apparatuses for selective monitoring of multiple silicon compounds in etchant solutions are provided. Methods can include reacting a test solution comprising a plurality of different silicon compounds with a fluoride-based compound in several conditions to provide different silicon:reagent binding ratios. One of the conditions can include the addition of a co-solvent to the test solution. Concentrations of the multiple silicon compounds can be determined based on the different binding ratios of silicon:reagent. Methods can further include a measuring method such as silicon elemental analysis or measuring of functional groups of a certain silicon form of a first portion of a test solution comprising a plurality of different silicon compounds and reacting a second portion of the solution with a fluoride-based compound to provide a silicon:reagent binding ratio. Concentrations of the multiple silicon compounds can be determined based on the measuring method and binding ratio measurements.Type: GrantFiled: September 27, 2019Date of Patent: January 17, 2023Assignee: ECI TECHNOLOGY, INC.Inventors: Eugene Shalyt, Guang Liang
-
Patent number: 11549909Abstract: An elution apparatus and a detection apparatus are described. The elution apparatus includes: a sample trap for trapping a sample; and one or more pumps and/or valves to move a liquid eluent and a liquid eluate, wherein the eluate includes an extracted portion of the sample that is extracted by the eluent. The detection apparatus includes: a capillary having a low-voltage (LV) end portion to receive a sample; and a conductivity detector coupled to a high-voltage (HV) end portion of the capillary to generate signals based on conductivity of a monitored portion of the capillary in the HV end portion, wherein the conductivity detector is electrically isolated from the LV end portion.Type: GrantFiled: August 15, 2017Date of Patent: January 10, 2023Assignee: GREYSCAN PTY LTDInventors: Graham William Lyford, Michael Smith, Alistair Stuart Webb, Adam John Cusick, Leigh Ryan, Ian Emil Sohn
-
Patent number: 11549906Abstract: Various embodiments disclose an electronic circuit for an electrochemical gas sensor. The electronic circuit comprises a first switching element electrically coupled to a reference terminal of the electrochemical gas sensor and a ground voltage terminal. Further, the electronic circuit comprises a second switching element electrically coupled to a sensing terminal of the electrochemical gas sensor and the ground voltage terminal. In an instance in which the electrochemical gas sensor is powered OFF, the first switching element and the second switching element are configured to electrically couple the reference terminal and the sensing terminal to the ground voltage terminal such that current generated when the sensing electrode and the target gas react while the electrochemical gas sensor is powered OFF flows to the ground voltage terminal and the potential of the reference terminal and the sensing terminal remain the equal.Type: GrantFiled: December 12, 2019Date of Patent: January 10, 2023Assignee: HONEYWELL INTERNATIONAL INC.Inventors: Keith Francis Edwin Pratt, Guoliang Li, Jia Wu, Fuyin Liu, Ian Underhay, Arek Majczak
-
Patent number: 11536687Abstract: A sensor element includes an element body including an oxygen-ion-conductive solid electrolyte layer, the element body having a longitudinal direction, a measurement electrode disposed in the element body, a reference electrode disposed in the element body so as to come into contact with a reference gas, and a heater configured to heat the solid electrolyte layer. A center of gravity of the reference electrode overlaps the measurement electrode as viewed in a thickness direction of the solid electrolyte layer. A length of each of the reference electrode and the measurement electrode in a front-rear direction is less than or equal to 1.1 mm, the front-rear direction being a direction along the longitudinal direction of the element body. An area of the reference electrode as viewed in the thickness direction is greater than or equal to 1.0 mm2.Type: GrantFiled: March 16, 2020Date of Patent: December 27, 2022Assignee: NGK INSULATORS, LTD.Inventors: Yusuke Watanabe, Shiho Iwai
-
Patent number: 11536681Abstract: The invention provides a solid state reference electrode comprising a reference element embedded in an electrochemically active composite, the electrochemically active composite comprising a polymeric matrix loaded with a solid inorganic salt, wherein the polymeric matrix comprises a cross-linked vinyl polymer of a vinyl monomer containing a heteroatom.Type: GrantFiled: May 4, 2018Date of Patent: December 27, 2022Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATIONInventors: Mikko Vepsäläinen, Colin David Wood, Miao Chen, Durga Prasad Acharya, David Simon Macedo
-
Patent number: 11536680Abstract: Electrochemical sensors include a housing within which an electrolyte is provided over the electrodes. The housing includes an active region, which is the area around the electrodes in which the electrolyte must be positioned to ensure correct operation of the device. The inner walls, base and ceiling of the housing are coated in either hydrophobic or hydrophilic materials, or both, so as to encourage the electrolyte to take a position over the active region, which is defined by the position of the electrodes. In some electrochemical sensors, a combination of hydrophobic and hydrophilic materials is used and the materials can be arranged in a pattern, which encourages the electrolyte to take a position over the active region.Type: GrantFiled: November 14, 2019Date of Patent: December 27, 2022Assignee: Analog Devices International Unlimited CompanyInventors: Alfonso Berduque, Youri Victorovitch Ponomarev, Brendan Cawley, Donal McAuliffe, Raymond J. Speer
-
Patent number: 11536684Abstract: A biosensor for measuring an electrical response from a biological sample. The biosensor includes a substrate, a passivation layer grown on a surface of the substrate, a patterned catalyst layer deposited on the passivation layer, and three electrodes grown on the patterned catalyst layer. The three electrodes include a working electrode, a counter electrode, and a reference electrode. The working electrode includes a first array of electrically conductive biocompatible nanostructures that is configured to be an attachment site for the biological sample. The counter electrode includes a second array of electrically conductive biocompatible nanostructures that is configured to acquire the electrical response from the working electrode. The reference electrode includes a third array of electrically conductive biocompatible nanostructures that is configured to adjust a specific voltage around the working and the counter electrodes.Type: GrantFiled: March 10, 2020Date of Patent: December 27, 2022Assignee: NANO HESGARSAZAN SALAMAT ARYAInventors: Mohammad Abdolahad, Hani Shashaani, Mahsa Faramarzpour
-
Patent number: 11530443Abstract: A method of detecting a lipid bilayer formed in a cell of a nanopore based sequencing chip is disclosed. An integrating capacitor is coupled with a lipid membrane, wherein the lipid membrane is between a working electrode and a counter electrode. An alternating current (AC) voltage is applied to the counter electrode. A voltage across the integrating capacitor is periodically sampled by an analog-to-digital converter (ADC). A change in the sampled voltage across the integrating capacitor in response to a change in the AC voltage is determined. Whether the lipid membrane comprises a lipid bilayer is detected based on the determined change in the sampled voltage across the integrating capacitor in response to the change in the AC voltage.Type: GrantFiled: June 3, 2020Date of Patent: December 20, 2022Assignee: Roche Sequencing Solutions, Inc.Inventors: Kevin Aliado, Roger J. A. Chen, Jing Luo, William Nielsen, Kyle Umeda, Ashraf Wahba