Abstract: Systems, apparatus and methods for disinfection of airflow. An apparatus for disinfecting air-conditioned airflow in a confined space includes: a modular housing; and a disinfection chamber enclosed within the housing. The disinfection chamber includes a plurality of disinfection sheets. Each disinfection sheet comprises a plurality of ultraviolet (UV) light sources. The airflow is configured to be routed along a serpentine pathway within the housing to expose microorganisms in the airflow to far UV-C light emitted by the UV light sources for an extended and optimal duration.

Abstract: A switching valve includes a rotor having a pair of rollers rotatably mounted on both ends thereof, a rotor drive unit rotationally driving the rotor, a pair of pressing members, each being provided at a position where each of the pair of pressing members cooperates with each of the pair of rollers outside a revolution orbit of each of the pair of rollers revolving by rotation of the rotor, and a pair of tubes, each being disposed between the revolution orbit of each of the pair of rollers and each of the pair of pressing members. A rotation center axis of the rotor is disposed on a straight line connecting centers of rotation of the pair of rollers, and each pressing member has the pair of pressing areas symmetrical with respect to a straight line passing through the center of rotation of the rotor and extending a vertical direction.

Abstract: Disclosed herein is a sterilizable adapter for a cell culture vessel comprising a body, an upper connection and/or a lid, at least one port, a ventilation passage, a lower internal connection suitable for connection to a cell culture vessel and a cell retention device and/or a cell separation device as well as a device comprising said sterilizable adapter and a method for cell cultivation using said sterilizable adapter.

Abstract: The invention relates to a device for isolating stem cells from fetal tissues, which device has an incubation chamber, at least one pump, at least one reservoir for a tissue break-down solution, at least one reservoir for a rinsing solution, optionally a control unit, optionally a means for removing contaminants, and optionally a means for expansion of the isolated stem cells. The invention further relates to a method for isolating stem cells from fetal tissue, which method comprises, among other things, the mechanical dissociation and the enzymatic digestion of the fetal tissue and optionally density gradient centrifugation for removing contaminants. The device and the method according to the invention are particularly suitable for isolating mesenchymal stem cells from fetal tissues, such as umbilical cord tissue, placenta tissue, or fetal lung tissue.

Abstract: A decontamination assembly, for pharmaceutical applications includes at least one chamber to be decontaminated (4) having a decontamination liquid storage tank (36) by which several atomizers (A, B, C. D) disposed in the chamber to be decontaminated (4) for producing a decontaminant aerosol can be supplied with decontamination liquid using valves (27) which can be controlled by electronic control, the atomizers (A, B, C, D) being in fluid communication with a ring conduit (32) having an inlet (33) and a separate outlet (34) by the valves (27), decontamination liquid from the decontamination liquid storage tank (36) being conveyable into the inlet of the ring conduit by a pump (35) and decontamination liquid flowing out of the outlet of the ring conduit back into the decontamination liquid storage tank (36), and a pressure adjustment mechanism (37) for keeping the pressure in the ring conduit (32) at a predefined liquid pressure range assigned to the ring conduit (32).

Abstract: A sample storage apparatus includes: a lid member; a sample storage container; first and second fluid sucking sections; first and second fluid discharging sections; first to fourth flow paths; and a first fluid identification sensor. The first flow path is connected to the first fluid sucking section, the second flow path is connected to the second fluid sucking section, the third flow path is connected to the first fluid discharging section, and the fourth flow path is connected to the second fluid discharging section. The first fluid identification sensor for identifying a fluid is disposed in the first flow path.

Abstract: A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.

Abstract: Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.

Abstract: The present invention generally relates to compositions and methods for neutralizing acidic streams in an olefin or styrene production plant. More specifically, the invention relates to neutralizing agents for dilution steam systems in the steam cracker process and their use for reducing acid corrosion and fouling in such systems.

Abstract: The present disclosure provides a membrane separation method of a cell suspension which can appropriately separate cells from debris, and a cell culture device. That is, membrane separation processing of the cell suspension is performed using a filtration membrane which includes an inlet-side opening formed on one surface and an outlet-side opening, which is formed on the other surface and communicates with the inlet-side opening, and in which the inlet-side opening and the outlet-side opening are disposed at positions deviated in a direction parallel to the surfaces of the membrane.

Abstract: A liquid filtration system comprising a syringe pump comprising a gas chamber and a movable plunger, wherein the gas chamber has an aperture at a first end and the plunger forms a seal within the internal walls of the chamber; a liquid chamber having two openings, the openings positioned at opposite ends of the chamber and the first opening connected to the aperture of the gas chamber; a bioreactor in fluidic communication with the second opening of the liquid chamber; a filter arranged to filter liquid passing between the bioreactor and the liquid chamber, the filter comprising a permeate outlet for removing filtered liquid; wherein, in use, the plunger may be moved in a reciprocating motion causing a corresponding movement of gas which drives liquid alternately between the liquid chamber and the bioreactor such that liquid passes through the filter and filtered liquid may be removed via the permeate outlet.

Abstract: Disclosed are apparatuses, systems, and methods for performing electroporation.

Abstract: A device for cultivating tissue sections, in particular for testing active ingredients and/or medications, includes a frame, at least one carrier component designed to hold a tissue section, and at least one liquid-absorbing strip element. The frame is designed to hold the at least one carrier component and the at least one strip element. A cultivation system includes the device for cultivating tissue sections and a holding vessel. The device can be used for testing active ingredients or medications on a tissue (section).

Abstract: A microorganism evaluation system comprising a viewing section for image acquisition, the viewing section comprising a viewing port configured to accommodate a fluid flow, at least one independently controlled imaging light source operably installed in the viewing section and configured to selectively illuminate the viewing port, and at least one independently controlled light stimulation device operably installed in the viewing section and configured to selectively emit light for invoking a motile response in a microorganism within the fluid flow in the viewing port, whereby the system synchronizes illumination of the at least one imaging light source and the at least one light stimulation device of the viewing section.

Abstract: The present invention discloses a nucleic acid extraction apparatus and a method using the apparatus for extracting nucleic acids and amplifying target nucleic acids. The nucleic acid extraction apparatus comprising: a nucleic acid extraction element, a waste storage chamber, and a reaction chamber, wherein the reaction chamber is selectively in communication with the nucleic acid extraction element and the waste storage chamber, and the apparatus realizes fluid exchange through the pressure between the waste storage chamber and the reaction chamber. In the present invention, by using an integrated control system, the conventional manual process of nucleic acid extraction and purification is integrated into a fully automatic closed process, making the operation more conveniently and quickly and improving the efficiency of experimental work.

Abstract: A system for the remote live auditing of biological samples contained in a cold storage vessel (10). The vessel (10) comprises one or more canisters (100(1), 100(2)), each of which comprises a connector (102(1), 102(2)) and is configured to hold at least one container (50), each of which contains one or more biological samples and has associated therewith an RFID tag identifying the container (50) in question. The system further comprises a docking assembly (200) mounted on the vessel (10) and comprising a plurality of connectors (202), each of which is configured to engage with the connector (102(1), 102(2)) of one of said canisters (100(1), 100(2)), thereby providing an electrical connection between the docking assembly (200) and the canister (50) in question.

Abstract: A cell treatment system includes an analysis unit to calculate the area or size of each of cell aggregates existing on the cell culture vessel based on an image; a display device to show the area or size of each of the cell aggregates on a display; a laser irradiator to emit laser toward the cell culture vessel so as to kill cells existing on the cell culture vessel; an input device to receive an operation input designating cells to be killed with irradiation of the laser or cells to survive without the irradiation of the laser among the cells existing on the cell culture vessel, or an operation input designating a position to be irradiated with the laser or a position not to be irradiated with the laser on the cell culture vessel; and a control unit to control a position irradiated with the laser.

Abstract: An airlift bioreactor for perfusion cell culture comprises a single- or multi-tiered riser for working volume scale-up, an internal inclined gravity settler for cell retention, an outlet port for cell-free spent culture medium removal, and an inlet port for fresh medium addition.

Abstract: A filtering facepiece respirator decontamination device includes an enclosure defining a UV irradiation chamber, at least one UV lamp positioned in the irradiation chamber, a moveable drawer comprising a platform for positioning a respirator, wherein the moveable drawer can move to a closed position in the respirator positioned on the platform is located in the irradiation chamber, a switch for detecting that the drawer is in the closed position, and a controller for activating the at least one UV lamp based on the switch detecting that the drawer is in the closed position.

Abstract: A disinfectant device including a pouch, the pouch including a first layer of material coupled to a second layer of material and defining a compartment therebetween. At least one dry reactant is retained within the compartment, the at least one dry reactant producing chlorine dioxide gas when exposed to water. A wick is at least partially disposed within the compartment. At least one from the group consisting of the first layer of material and the second layer of material define an array of ports along a periphery of the pouch and an array of fluid conduits, the array of fluid conduits being proximal to the array of ports, offset from the array of ports, in fluid communication with the wick, the compartment, and the array of ports.