Abstract: A blood pump for supporting the heart may be provided that includes: a rotor with delivery elements; a rotor drive; a pressure sensor; and a regulating device that regulates a pressure or a hemodynamic parameter by means of control of the rotor drive. The pressure and/or the hemodynamic parameter may be determined by means of one or a plurality of hemodynamic sensors and/or from operating parameters of the pump. The regulating device may be suitable for regulating a hemodynamic parameter successively, such as periodically, to different target values. Using such regulation, the blood pump may be operated in an optimized manner, and operation of the blood pump may be varied in a targeted and patient-protective manner in order to attain certain goals.

Abstract: A system and method for ECG data classification for use in facilitating diagnosis of cardiac rhythm disorders is provided. ECG data is obtained via an electrocardiography monitor shaped for placement on a patient's chest. The ECG data is divided into segments and noise detection analysis is applied to the ECG data segments. A noise classification or a valid classification is assigned to each segment of the ECG data. At least one ECG data segment assigned the noise classification and that includes ECG data that corresponds with feedback from the patient via the electrocardiography monitor is identified. The ECG data that corresponds with the patient feedback is removed from the identified ECG data segment with the noise classification. The ECG data segments assigned the noise classification are removed from further analysis.

Abstract: The present invention relates to a non-invasive device and method for treating and improving dysfunction or disorders associated with pelvic floor. In one advantageous form, the non-invasive device comprising a generator configured to generate a current with a predetermined intensity of milliampere at a desirable frequency; at least one electrical stimulation applicator comprising a probe unit configured to transmit the current to a target body surface of vulvar tissues and/or pelvic floor muscle for application of an electrical stimulation; wherein the probe unit comprises a negative electrode and at least one positive electrode and the probe unit is shaped for positioning on the target body surface of the vulvar tissues and/or the pelvic floor muscle.

Abstract: Disclosed herein is a screw-in lead implantable in the pericardium of a patient heart and a system for delivering such leads to an implantation location. The leads include a helical tip electrode and a curate body including a defibrillator coil with improved contact between the defibrillator coil and the patient heart. The delivery system includes a delivery catheter and lead receiving sheath disposed within the catheter. A fixation tine is disposed on one of the delivery catheter and the lead receiving sheath such that the delivery system may be anchored into the pericardium during fixation of the screw-in lead. In certain implementations, an implantable sleeve receives the leads to bias the defibrillator coil against the patient heart.

Abstract: An electrocardiography monitor configured for self-optimizing ECG data compression is provided. ECG waveform characteristics are rarely identical in patients with cardiac disease making this innovation crucial for the long-term data storage and analysis of complex cardiac rhythm disorders. The monitor includes a memory and a micro-controller operable to execute under a micro-programmable control and configured to: obtain a series of electrode voltage values; select one or more of a plurality of compression algorithms for compressing the electrode voltage series; apply one or more of the selected compression algorithms to the electrode voltage series; evaluate a degree of compression of the electrode voltage series achieved using the application of the selected algorithms; apply one or more of the compression algorithms to the compressed electrode voltage series upon the degree of compression not meeting a predefined threshold; and store the compressed electrode voltage series within the memory.

Abstract: Implantable medical devices (IMD) such as a cardiac pacemakers may include a sensor and electrodes. In some cases, the IMD may include electronics to use the sensor to determine the heart rate of a patient's heart. The electronics may use the electrodes to deliver pacing pulses to the heart at a first energy level if the heart rate is below a threshold and pace the heart at an enhanced energy level if the heart rate is above the threshold.

Abstract: A multifunctional therapeutic device for providing therapy to human body is disclosed. The device incorporates means for any one or combination of different therapies, namely electric pulse therapy, UV therapy, Low energy laser therapy, and heat therapy, that can be operated individually or simultaneously as per requirement. The device is double ended with each end incorporating capability to impart each of the therapies either individually or in combination. One end is configured for therapy to a smaller area, and the other end configured to provide therapy to a larger area of human body. Two identical laser devices are used along with converging and diverging coupling systems to focus laser to a smaller or larger area. Device includes a single display that rotates the displayed data depending on which side is being used; and includes a hand wheel for adjusting intensity of therapy that allows ambidextrous application.

Abstract: A system and method for performing deep brain stimulation (DBS) therapy are provided. The method and system include pre-operatively acquiring at least one pre-operative image of the brain with at least one imaging sub-system and determining a location of a Nucleus Basalls of Meynert (NBM) for therapy in the at least one pre-operative image, and intra-operatively acquiring at least one intra-operative image of the brain after obtaining an access opening through the skull. The method and system further provide performing surgical planning based on the pre-operative image in the intra-operative image, advancing a lead having DBS electrodes on the lead to a target position proximate to or within the NBM area, and coupling the lead to an implantable pulse generator (IPG) configured to deliver DBS pulses through the DBS electrodes to the NBM. Further, the IPG is configured to deliver DBS pulses for treating symptoms associated with Alzheimer's disease.

Abstract: An information processing apparatus is described. This determines a physiological parameter of an individual, the apparatus comprising: image circuitry configured to obtain a series of images of a skin exposed region of the individual; and processing circuitry configured to perform a periodogram on at least one of the red, green and blue channels of the skin exposed region of the series of images to obtain frequency components of the channel; and to determine the physiological parameter based on the periodogram.

Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

Abstract: Technologies and techniques for detecting and alerting onset Autism Spectrum Disorder (ASD), where a device receives sensor data including heart rate data, accelerometer data and audio data. The device is configured to activate the collection of accelerometer data and extract accelerometer data features comprising frequency components if the heart rate exceeds a first threshold, activate the collection of audio data and extract audio data features comprising frequency components if the heart rate data meets or exceeds a second predetermined threshold, determine if the audio data meets or exceeds a predetermined audio threshold comprising frequency characteristics, and transmit an alert indicating the detection of an onset ASD episode, based on the extracted audio data features, the extracted accelerometer data features and the heart rate data.

Abstract: A system for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer is provided. A download station retrieves cutaneous action potentials of a patient recorded over a time by an ECG device as ECG data. An R-R interval plot of the ECG data includes R-R intervals plotted along an x-axis of the plot and heart rates associated with the R-R intervals plotted along a y-axis. The R-R intervals are calculated as a difference between recording times of successive pairs of R-wave peaks. Each heart rate is associated with each time difference. One or more portions of the R-R intervals are identified in the plot. Each portion of the R-R intervals includes a cardiac event. Report strips are generated and each includes one portion of the R-R intervals and a portion of the ECG data. The report strips are included in a cardiac report for the patient.

Abstract: In an example, an implantable medical device (IMD) includes a hold capacitor configured to deliver an electrical therapy pulse, and charge pump circuitry configured to transfer energy from the battery to the hold capacitor. In this example, the charge pump circuitry comprises a plurality of capacitors, and switching circuitry configured to put the charge pump circuitry into a K-factor mode selected from a group of K-factor modes by opening and closing a combination of switches connected to the plurality of capacitors.

Abstract: An adapter for coupling a laser treatment device to an object for treatment. The adapter has an input side, which may be fixed relative to the laser treatment device, by a locking mechanism and which may be fixed to the object, for alignment of the object relative to the laser treatment device. A scanned laser beam is introduced on the input side, from the laser treatment device, along a beam path to the object with a reference structure. The reference structure lies on the beam path of the adapter and may be optically detected by means of the laser beam scanned over the region.

Abstract: An arrangement may include a first system provided for processing physiological data representative of a beating heart. The first system may be adapted to execute a process for using at least one pattern to detect a notable finding in the physiological data and for sending the notable finding to a second system. The second system may be adapted to execute a process for analyzing the notable finding, for determining at least one new pattern to send to the first system, and for sending the at least one new pattern to the first system. The at least one new pattern may also include a rule that includes a set of conditions and an action to perform if the set of conditions is met.

Abstract: A method for ablating a uterine endometrium enlarges an expandable-contractible frame to expand a compliant energy-delivery surface into a planar triangular shape and engage the surface against the walls of a patient's uterine cavity. The frame has flexible outer elements in lateral contact with the compliant surface and flexible inner elements not in said lateral contact, wherein the inner flexible element and outer flexible elements have substantially dissimilar material properties. Energy is applied through the compliant energy-delivery surface to ablate the endometrium.

Abstract: This disclosure relates to an active medical device which includes a generator for producing multiphase nerve stimulation pulse trains, each pulse train including at least one stimulation pulse preceded by a precharge pulse and ending with a passive discharge pulse. The active medical device also includes a sensor configured to output a control signal representative of a physiological and/or physical parameter capable of being influenced by the output of nerve stimulation pulse trains. The active medical device also includes an automatic charge compensation control circuit configured to receive at the input the control signal output by the sensor, determine an amplitude and/or a precharge pulse time as a function of at least one predetermined criterion, and output to the generator a precharge pulse control signal to be produced at the output.

Abstract: Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency.

Abstract: There is provided a cochlear implant system, comprising a sound processor for generating an auditory nerve stimulation signal from an input audio signal; an implantable stimulation assembly comprising an electrode array for electrical stimulation of the cochlea according to the neural stimulation signal; and an electrode migration monitoring unit including a unit for capturing ECAP signals induced at the electrodes of the electrode array in response to stimulation of the cochlea by applying auditory nerve stimulation signals to the electrodes, an electrode migration detection unit for detecting electrode migration relative to the cochlea by comparing presently captured ECAP signals and/or ECAP data derived from such presently captured ECAP signals to stored previously captured ECAP signals and/or ECAP data derived from such previously captured ECAP signals, and a unit for outputting an alarm signal in case that electrode migration is detected by the electrode migration detection unit.

Abstract: A patient adapter for connecting a driveline cable between an implantable blood pump and a controller. The patient adapter provides a sufficiently large form factor to make connecting ends of a driveline cable easy for patients who lack dexterity or have unclear vision. The patient adapter includes an adapter body that defines a central lumen that extends through an entire length of the adapter body. The central lumen is configured to receive an end of a percutaneous end connector of the driveline cable and an end of a controller end connector of the driveline cable. The patient adapter includes a first mating feature configured to engage a corresponding feature of the percutaneous end connector and a second mating feature configured to engage a corresponding feature of the controller end connector. A thickness of the adapter body is greatest at a position proximate the controller end connector.