Abstract: Systems and methods are provided for extending dialogue between a mobile device and a point-of-interaction (POI). One example computer-implemented method includes receiving, by a conduit server, from the POI, via a first connection between the conduit server and the POI, a request for an extended connection between the POI and the mobile device, and notifying a host server of the request. The method then includes receiving, from the mobile device, via a second connection between the conduit server and the mobile device, an identifier for the mobile device and pairing, based on the identifier, the first and second connections, to establish a wireless connection between the POI and the mobile device, via the conduit server. The method further includes submitting a wake-up call to the mobile device, whereby the mobile device publishes the identifier to establish a wireless connection directly between the POI and the mobile device.

Abstract: A system comprising a pumping system configured to pump respective exhaust gases from each of a plurality of chemical etching process chambers and to combine the exhaust gases to provide a combined exhaust gas, and a noble gas recovery system configured to process the combined exhaust gas to remove one or more noble gases therefrom.

Abstract: The invention relates to compounds of formula (A) and formula (I): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are ?v?6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: Systems, methods, and process nodes for managing bandwidth in a telecommunications network include or implement operations of receiving a connection request from a wireless communication device capable of communication in a first band having a first frequency and in a second band having a second frequency; receiving a capability report from the wireless communication device; and in response to a determination that the capability report meets a criteria, assigning the wireless communication device to communicate in the second band.

Abstract: A device for creating reactive oxygen and reactive nitrogen species comprising: a plasma generator comprising at least one electrode positioned within an open-ended chamber and a centrifugal mixing chamber in fluid communication with the plasma generator, said centrifugal mixing chamber comprising a mixing chamber side wall and a blade, said blade oriented to allow passage of air in a circular motion around a central post of said centrifugal mixing chamber, and an exit nozzle on an opposing end of said centrifugal mixing chamber.

Abstract: A luminaire includes a housing, a light diffusion panel, a reflective surface, and a plurality of light sources. The light diffusion panel includes a light source aperture, an edge surface bounding the light source aperture, and an emission surface. The emission surface includes first and second emission surface sections. The second emission surface section is disposed on an opposite side of the light source aperture from the first emission surface section. The reflective surface is disposed on a side of the light diffusion panel opposite the emission surface. The light sources project light into the light diffusion panel through the edge surface. The light sources include first and second light sources. The first light source projects light into the light diffusion panel and through the first emission surface section. The second light source projects light into the light diffusion panel and through the second emission surface section.

Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.

Abstract: Enhancements to existing gaming controllers facilitating expedient response time and fine-tuned accuracy are described. The enhancements comprise the internal modification of the stock resistance force supplied by the analog stick centering spring mechanism. Through modification, the force of resistance supplied may be increased to over 200 grams of force, or down to 40 grams of force, while maintaining full function of the analog stick mechanism. A second primary enhancement replaces the stock triggers, conventionally equipped with progressive resistance sensors, to a momentary ‘snap-action’ two-way switch, minimizing trigger pull distance, and removing the analog nature of the trigger to achieve optimal performance.

Abstract: An emergency wayfinding device includes a lighting circuit constructed and arranged to change at least one property of a light emitted from a light emitting element, and an electrical conduit including a plug. The plug of the electrical conduit is constructed configured to be received in a socket and to draw electricity from the socket to power the lighting circuit via the electrical conduit.

Abstract: The invention provides a pharmaceutical combination including an ?v?1 integrin inhibitor and at least one additional therapeutic agent for preventing, delaying or treating liver diseases or disorders. The additional therapeutic agent may be an SGLT1/2 inhibitor, among a diverse selection of agents. For example, the pharmaceutical combination includes (S)-2-(4-methyltetrahydro-2H-pyran-4-carboxamido)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl) nonanoic acid (Compound 1) and at least one additional therapeutic agent.

Abstract: The invention provides a pharmaceutical combination including an ?v?1 integrin inhibitor and at least one additional therapeutic agent for preventing, delaying or treating liver diseases or disorders. The at least one additional therapeutic agent may be a farnesoid X receptor (FXR) agonist. For example, the pharmaceutical combination includes (S)-2-(4-methyltetrahydro-2H-pyran-4-carboxamido)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid (Compound 1) and 2-[3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1, 3-ben-zothiazole-6-carboxylic acid (tropifexor).

Abstract: The invention relates to compounds of formula (A) and formula (I): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are ?v?6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: Techniques for managing sequencing requests for storage node operations based on types of operations being sequenced. The techniques manage sequencing requests for different types of operations, such as backup and recovery operations, replication operations, migration operations, and so on, in a manner that avoids overwhelming storage node capacity. The techniques include receiving a sequencing request for an operation of a specified operation type at a request manager of a storage node and determining whether a capacity of the storage node is available for running the operation by a capacity manager for the specified operation type, in which the capacity manager is provided by a storage client and implemented on the storage node separate from the request manager. In this way, throttling, limiting, and/or prioritization requirements of the operation of the specified operation type can be defined by the storage client in a manner agnostic to the request manager.

Abstract: An emergency wayfinding device including a lighting controller, a lighting circuit, and a light emitting element. The emergency wayfinding device may draw electricity through a twist-lock plug or draw it from a power source such a battery or a photovoltaic cell. The wide-area communications device is in electrical communication with a connected lighting controller and is configured to send and receive signals or messages to and from a central broadcasting device as well as other emergency wayfinding devices. The lighting controller is configured to change a property of light emitted from a light emitting element based upon signals or messages received by a wide-area communications device. The wide-area communications device communicates a received message or signal to the lighting controller and the lighting controller generates a lighting control signal or message.

Abstract: In User Equipment (UE) at various geographic locations, circuitry exchanges TCP packets with radios, and the radios wirelessly exchange the TCP packets with wireless communication nodes. The circuitry determines TCP retransmission rates for the radios at the geographic locations. The circuitry estimates TCP retransmission rates for the radios at a new geographic location based on the TCP retransmission rates for the radios at the past geographic locations. The circuitry selects one of the radios based on the estimated TCP retransmission rates at the new geographic location. At the new geographic location, the circuitry exchanges new TCP packets with the selected one of the radios, and the selected one of the radios wirelessly exchanges the new TCP packets with one of the wireless communication nodes.

Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.

Abstract: Enhancements to existing gaming controllers facilitating expedient response time and fine-tuned accuracy are described. The enhancements comprise the internal modification of the stock resistance force supplied by the analog stick centering spring mechanism. Through modification, the force of resistance supplied may be increased to over 200 grams of force, or down to 40 grams of force, while maintaining full function of the analog stick mechanism. A second primary enhancement replaces the stock triggers, conventionally equipped with progressive resistance sensors, to a momentary ‘snap-action’ two-way switch, minimizing trigger pull distance, and removing the analog nature of the trigger to achieve optimal performance.

Abstract: Animal litter boxes are provided which include a sensor to detect a change in an environment within an interior of its housing and an odor removal device (ORD) operationally connected to the sensor such that the ORD is activated in response to a signal from the sensor. In some cases, the ORD is configured to operate in different manners based on respectively different signals from the sensor. In addition or alternatively, the litter boxes may include a timer configured with the sensor for activating and periodically reactivating the ORD at preset time intervals in response to a sensor signal. In yet other embodiments, the litter boxes may additionally or alternatively include a timer having user adjustable settings of different time periods at which to initiate activation of the ORD and/or user adjustable settings of different durations at which to operate the ORD, both in response from a sensor signal.

Abstract: The invention relates to compounds of formula (A): or a salt thereof, wherein R1, R2, R5a, R5b, R6a, R6b, R7a, R7b, R8a, R8b, R9a, R9b, R10a, R10b, R11a, R11b, R21, n, and G are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are ?v?6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: A mobile User Equipment (UE) uses Transmission Control Protocol (TCP) to deliver mobile data services over different radios. The mobile UE qualifies the individual radios that have adequate signal strength at a geographic location. The mobile UE estimates TCP retransmission rates at the location for the qualified radios. The mobile UE identifies individual qualified radios that have adequate TCP retransmission rate estimates. The mobile UE selects one of the identified radios that has the lowest power usage. The mobile UE exchanges TCP packets over the selected radio which includes participating in TCP retransmissions at the location. The selected radio wirelessly exchanges the TCP packets with a wireless access node. The mobile UE stores resulting TCP retransmission data for the selected radio in association with the location for future TCP retransmission rate estimates.