Abstract: In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.

Abstract: An invention is disclosed for using touch input to display a representation of information for an item of a plurality of grouped items not otherwise accessible via other touch input. In an embodiment. In an embodiment, a user provides touch input to a touch-input device that comprises a scrubbing motion. Where the scrub corresponds to interacting with an item of a plurality of grouped items, a representation of information not otherwise accessible via other touch input is displayed (such as an infotip). In this manner, touch input may serve as a way to obtain a mouse-over event where there is no mouse pointer with which to create a mouse-over.

Abstract: The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal infections.

Abstract: The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal infections.

Abstract: A vehicle slide assembly (10) comprising a first rail assembly (12) and a second rail assembly (14) substantially parallel to the first rail assembly (12). Each rail assembly comprises a guide rail (20) and the slide assembly further comprises a vehicle wheel receiving platform (16, 18) engageable with a guide rail (20) and adapted to slide along a rail assembly by means of the guide rail.

Abstract: Indicator devices, systems, and methods are provided. Indicator devices include a housing having a bore and an indicating component placed therein. The indicator devices are activated in response to an increase in temperature or pressure. Indicator systems include an indicator device coupled to a housing, such as a conduit or enclosure. Methods include utilizing an indicator device to determine if an area within a conduit or enclosure has been sealed.

Abstract: Methods and uses for the treatment and prevention of cardiac and cardiovascular diseases comprising administration of a GLP-1 agonist.

Abstract: A sensor is coupled to a device positioned within an enclosure and is configured to determine the status of the device or its surrounding environment. The sensor transmits the information to a central computer and/or a local indicator. Once the information is received at the central computer, the information is processed for the operators and maintainers to interpret. Based on the information received, the operators and maintainers may implement procedures to maintain the device or its surrounding environment under observation. In certain embodiments, the central computer provides instructions to a second device within or adjacent to the enclosure to implement corrective actions. In some embodiments, the sensor is coupled to a microcontroller which performs analysis received from the sensor and provides instructions to the second device to implement corrective actions.

Abstract: Environmental conditions within an enclosure containing critical equipment and devices are monitored and when outside of acceptable parameters corrective action is taken to modify these environmental conditions so as to bring them within acceptable limits. Unless an environmental condition is outside of an acceptable limit, no energy expenditure is made by the environmental conditioning equipment since it does not need to be in use. When the environmental conditioning equipment is called into operation, its environmental modification influence is monitored to determine if the expected environmental modification is occurring within an expected time period(s). If the expected environmental modification does not occur within the expected time period, and/or does not occur at an expected time rate of change, then an alarm is generated to indicate that maintenance may be required for the environmental conditioning equipment.

Abstract: Method of identifying an anti-fungal agent which targets as an essential protein or gene of a fungus comprising contacting a candidate substance with (i) a protein which comprises the sequence shown by SEQ ID NOS: 3, 6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36, 39, 42, 45, 48, 50, 53, 56, 59, 61 or 63, or (ii) a protein which has 60% identity with (i), or (iii) a protein comprising a fragment of (i) or (ii) which fragment has a length of at least 50 amino acids, or (iv) a polynucleotide that comprises a sequence which encodes (i), (ii) or (iii), or (v) a polynucleotide comprising a sequence which has at least 70% identity with the coding sequence of (iv), and determining whether the candidate substance binds or modulates (i), (ii), (iii), (iv), or (v), wherein binding or modulation of (i), (ii), (iii), (iv), or (v) indicates that the candidate substance is an anti-fungal agent.

Abstract: A slurry coating composition is described, which is very useful for enriching the surface region of a metal-based substrate with aluminum. The composition includes colloidal silica and particles of an aluminum-based powder, and is substantially free of hexavalent chromium. The slurry may include colloidal silica and an alloy of aluminum and silicon. Alternatively, the slurry includes colloidal silica, aluminum or aluminum-silicon, and an organic stabilizer such as glycerol. The slurry exhibits good thermal and chemical stability for extended periods of time, making it very useful for industrial applications. Related methods and articles are also described.

Abstract: The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal infections.

Abstract: The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1: provided that the sum of a and b is 0 or 1; T is O or NH Ar1 is a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S, and being optionally substituted by one or more substituents R1; Ar2 Js a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S and being optionally substituted by one or more substituents R2; and R1 and R2 are as defined in the claims. The compounds are inhibitors of kinases and in particular FLT3, FLT4 and Aurora kinases.

Abstract: A system that includes a host and a peripheral device. The host transmits a packet that includes a command and a flow control field. The peripheral device receives the packet and has the ability to execute the command, wherein the peripheral device can determine whether the command can be processed in a timely manner, and can update the packet's flow control field with flow control data based on the determination. The host receives the updated packet and has the ability to adjust the flow control of subsequent packets to the peripheral device based on the flow control data in the updated packet.

Abstract: A method for improving the speed and efficiency of transmitting data between two components in which the transmitted data is sent, at least partly, through a serial bus is shown. According to the method, the fields in the data frames being transmitted between the components are of a fixed length regardless of the amount of data that the receiving device can receive at one time. The data bits of the fixed-length frame correspond to the signals accepted as input by the receiving component.

Abstract: The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal infections.

Abstract: Devices and methods described herein can allow an installer to locate an electrical box preinstalled behind building material. This approach can minimize the number of cuts in the building material, which can save time and can prevent the unnecessary loss of or damage to material. In some embodiments, the devices and methods can identify a particular circuit or type of outlet box, switchbox, ceiling box, ceiling fan box, junction box, or other type of box. In one example, a radio frequency identification (RFID) tag is secured to the box, wherein the RFID tag comprises an RFID antenna. An RFID reader is configured to broadcast to and receive transmissions from the RFID tag, wherein the reader comprises a reader antenna configured to broadcast to and receive transmissions from the RFID antenna. The reader indicates the presence and location of an RFID tag secured to the box when the box is pre-installed behind a building material.

Abstract: Methods and uses for the treatment and prevention of cardiac and cardiovascular diseases comprising administration of a GLP-1 agonist.

Abstract: Luminaires or lighting fixtures and methods according to which the lighting fixture is suitable for use in a hazardous location. Generally, lighting fixtures comprise a first portion and a second portion coupled to the first portion, wherein only the first portion is explosion proof and/or flameproof. Generally, methods comprise providing a lighting fixture comprising first and second regions and positioning a light source in the first region of the lighting fixture.

Abstract: An organic coating composition is described, which can be used to enrich the surface region of a metal-based substrate with aluminum. The composition comprises an aluminum-based powder and at least one organic resin, e.g., alkyds, epoxies, or silicone materials. At least some of the aluminum-based powder is in the form of substantially spherical powder particles. The coating composition is substantially free of hexavalent chromium. It can be applied to the substrate by a variety of techniques, such as spraying. It is then heat-treated, to cause diffusion of aluminum into the surface region of the substrate, e.g., a turbine engine component. The composition exhibits good thermal and chemical stability for extended periods of time. Related articles are also described.