Patents by Inventor Jeffrey Wang
Jeffrey Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20160000860Abstract: The use of autogenous bone graft is the current gold standard in the 1.5 million bone-grafting surgeries performed annually in the United States. Although this practice has resulted in high rates of fusion success, it is associated with increased operative time and blood loss, along with a significant degree of donor-site morbidity. Additionally, in certain settings such as revision cases, multilevel constructs, or in patients with medical comorbidities, autogenous bone graft may exist in limited quantity and quality. This significant need for a suitable alternative to autogenous bone graft has stimulated great interest in the exploration of bone graft substitutes and extenders.Type: ApplicationFiled: June 30, 2015Publication date: January 7, 2016Inventors: Samuel S. Murray, Elsa J. Murray, Jeffrey Wang, Keyvan Behnam
-
Patent number: 9180485Abstract: Methods and apparatus for coating a medical device are provided. In one embodiment, the method for preparing a substantially uniform coated medical device includes (1) preparing a coating solution comprising a solvent, a therapeutic agent, and an additive; (2) loading a metering dispenser with the coating solution; (3) rotating the medical device about the longitudinal axis of the device and/or moving the medical device along the longitudinal or transverse axis of the device; (4) dispensing the coating solution from the metering dispenser onto a surface of the medical device and flowing the coating solution on the surface of the medical device while the medical device is rotating and/or linearly moving; and (5) evaporating the solvent, forming a substantially uniform coating layer on the medical device.Type: GrantFiled: March 18, 2013Date of Patent: November 10, 2015Assignee: Lutonix, Inc.Inventors: Jeffrey Wang, Harrison Malinoff, Lixiao Wang, Christopher M. Barry, Dennis W. Wahr, Scott R. Naisbitt
-
Publication number: 20150238553Abstract: The invention provides extracts and compositions derived from Tripterygium wilfordii for overcoming drug resist-ance in cancer therapy. This invention relates to organic solvent extracts of T. wilfordii and their use in cancer treatment, particularly in the treatment of cancers which have exhibited resistance to treatment by chemotherapeutic drugs. Methods of treating a cancer are disclosed. The method administers to a patient in need thereof a combination of (a) an organic solvent extract of T. wilfordii and (b) a chemotherapeutic drug. The organic solvent extract of T. wilfordii (a) and chemotherapeutic drug (b) are administered in a com-bined amount effective to treat the cancer. The cancer being treated is at least in part resistant to treatment by the chemotherapeutic drug (b) alone. Also disclosed are chemotherapeutic compositions comprising a combination of (a) an organic solvent extract of T.Type: ApplicationFiled: August 19, 2013Publication date: August 27, 2015Inventors: Moses Sing Sum Chow, Ying Huang, Jinghua Jeffrey Wang, Ranadheer Ravula, Zhi Jun Wang
-
Patent number: 9072709Abstract: The use of autogenous bone graft is the current gold standard in the 1.5 million bone-grafting surgeries performed annually in the United States. Although this practice has resulted in high rates of fusion success, it is associated with increased operative time and blood loss, along with a significant degree of donor-site morbidity. Additionally, in certain settings such as revision cases, multilevel constructs, or in patients with medical comorbidities, autogenous bone graft may exist in limited quantity and quality. This significant need for a suitable alternative to autogenous bone graft has stimulated great interest in the exploration of bone graft substitutes and extenders.Type: GrantFiled: June 23, 2010Date of Patent: July 7, 2015Assignees: The Regents of the University of California, The United States of America Represented by The Department of Veterans AffairsInventors: Samuel S. Murray, Elsa Murray, Jeffrey Wang, Keyvan Behnam
-
Patent number: 8975231Abstract: A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a variety of useful BBP compositions. BBP increases the over-all osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.Type: GrantFiled: June 1, 2012Date of Patent: March 10, 2015Assignees: The Regents of the University of California, The United States of America represented by the Department of Veterans AffairsInventors: Samuel S. Murray, Elsa J. Brochmann-Murray, Jeffrey Wang, Keyvan Behnam
-
Patent number: 8898145Abstract: A variety of query optimization techniques are described herein. A first query optimization technique, referred to herein as non-empty transformation, may be applied to queries that specify one or more measures, a dimensional context within which the measure(s) are to be evaluated, and a filter condition specifying that rows with only empty measure values be excluded from a result set. The non-empty transformation technique enables such queries to be rewritten into another format that can be executed more efficiently than the original queries. A second query optimization technique described herein involves restructuring an operator tree representation of a query so as to avoid unnecessary duplicated evaluation of extension columns. A third query optimization technique described herein automatically selects a minimum number of join columns having the lowest cardinality for implementing a join between two tables.Type: GrantFiled: June 15, 2011Date of Patent: November 25, 2014Assignee: Microsoft CorporationInventors: Yutong (Jeffrey) Wang, Marius Dumitru
-
Patent number: 8656048Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: GrantFiled: May 30, 2013Date of Patent: February 18, 2014Assignee: SimpleAir, Inc.Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Patent number: 8645346Abstract: A system and method for facilitating querying one or more data sources. A system provides mechanisms to enable flexible specification of user queries and generation of one or more SQL queries that correspond closely to corresponding user queries. An operator tree and a logical operator tree may be created as intermediate steps to generate the one or more SQL queries. Capabilities of data sources are determined and used to generate remotable SQL queries for composable queries, to reduce an amount of post-processing that is performed on result sets. The system enables user queries that extend beyond those defined by a data model.Type: GrantFiled: June 16, 2011Date of Patent: February 4, 2014Assignee: Microsoft CorporationInventors: Marius Dumitru, Jeffrey Wang
-
Patent number: 8639838Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: GrantFiled: May 31, 2013Date of Patent: January 28, 2014Assignee: SimpleAir, Inc.Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Patent number: 8601154Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: GrantFiled: January 31, 2011Date of Patent: December 3, 2013Assignee: SimpleAir, Inc.Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Patent number: 8572279Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: GrantFiled: January 31, 2011Date of Patent: October 29, 2013Assignee: SimpleAir, Inc.Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Publication number: 20130282872Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: ApplicationFiled: May 30, 2013Publication date: October 24, 2013Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Publication number: 20130282873Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: ApplicationFiled: May 31, 2013Publication date: October 24, 2013Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Patent number: 8489707Abstract: A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.Type: GrantFiled: April 21, 2006Date of Patent: July 16, 2013Assignee: SimpleAir, Inc.Inventors: John M. Payne, Tim Von Kaenel, Jeffrey Wang, Jeffrey Odell, David Starr, Jason Katz
-
Patent number: 8431673Abstract: The present invention relates to composition comprising at least one compound obtained from the reaction of at least one compound (i) having a refractive index nD20 of at least 1.50 comprising at least one isocyanate-reactable functional group —XH, wherein each of X is, independently, O or NR, at least one polyisocyanate (ii), and, optionally, at least one compound (iii) comprising at least one isocyanate-reactable functional group —YH and at least one curable functional group Q, wherein each of Y is, independently, O, NR or S, and its use for making high refractive index coatings and films.Type: GrantFiled: November 7, 2008Date of Patent: April 30, 2013Assignee: Cytec Surface Specialties S.A.Inventors: Zhikai Jeffrey Wang, Christopher Wayne Miller, Marcus Lee Hutchins, James C. Matayabas, Jr.
-
Patent number: 8430055Abstract: Embodiments of the invention relate to a method and apparatus for coating a medical device. In one embodiment, the method for preparing a substantially uniform coated medical device includes (1) preparing a coating solution comprising a solvent, a therapeutic agent, and an additive; (2) loading a metering dispenser with the coating solution; (3) rotating the medical device about the longitudinal axis of the device and/or moving the medical device along the longitudinal or transverse axis of the device; (4) dispensing the coating solution from the metering dispenser onto a surface of the medical device and flowing the coating solution on the surface of the medical device while the medical device is rotating and/or linearly moving; and (5) evaporating the solvent, forming a substantially uniform coating layer on the medical device.Type: GrantFiled: August 27, 2009Date of Patent: April 30, 2013Assignee: Lutonix, Inc.Inventors: Jeffrey Wang, Harrison Malinoff, Lixiao Wang, Christopher M. Barry, Dennis W. Wahr, Scott R. Naisbitt
-
Publication number: 20130095139Abstract: A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a variety of useful BBP compositions. BBP increases the over-all osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.Type: ApplicationFiled: June 1, 2012Publication date: April 18, 2013Applicants: Department of Veterans Affairs, The Regents of the University of CaliforniaInventors: Samuel S. Murray, Elsa J. Brochmann-Murray, Jeffrey Wang, Keyvan Behnam
-
Publication number: 20120323956Abstract: A system and method for facilitating querying one or more data sources. A system provides mechanisms to enable flexible specification of user queries and generation of one or more SQL queries that correspond closely to corresponding user queries. An operator tree and a logical operator tree may be created as intermediate steps to generate the one or more SQL queries. Capabilities of data sources are determined and used to generate remotable SQL queries for composable queries, to reduce an amount of post-processing that is performed on result sets. The system enables user queries that extend beyond those defined by a data model.Type: ApplicationFiled: June 16, 2011Publication date: December 20, 2012Applicant: Microsoft CorporationInventors: Marius Dumitru, Jeffrey Wang
-
Publication number: 20120323885Abstract: A variety of query optimization techniques are described herein. A first query optimization technique, referred to herein as non-empty transformation, may be applied to queries that specify one or more measures, a dimensional context within which the measure(s) are to be evaluated, and a filter condition specifying that rows with only empty measure values be excluded from a result set. The non-empty transformation technique enables such queries to be rewritten into another format that can be executed more efficiently than the original queries. A second query optimization technique described herein involves restructuring an operator tree representation of a query so as to avoid unnecessary duplicated evaluation of extension columns. A third query optimization technique described herein automatically selects a minimum number of join columns having the lowest cardinality for implementing a join between two tables.Type: ApplicationFiled: June 15, 2011Publication date: December 20, 2012Applicant: Microsoft CorporationInventors: Yutong (Jeffrey) Wang, Marius Dumitru
-
Patent number: 8259562Abstract: Systems and method for providing redundancy of communications and/or inline power to a powered Ethernet device are disclosed. A redundancy device is configured to receive in-line data and/or power from a plurality of Ethernet relay uplinks and to monitor communications between the relay uplinks. One of the relay uplinks is established as an active state uplink and passes data and/or power to the power device. Responsive to a switchover communication from a redundant uplink, the redundancy device establishes the redundant uplink as the active uplink, thereby passing data and/or power from the redundant uplink to the power device. The relay uplinks may use packet-based communication to sense when there is a failure in a link, and replace a failed device with a redundant device.Type: GrantFiled: March 7, 2005Date of Patent: September 4, 2012Assignee: Cisco Technology, Inc.Inventors: Michael Smith, Jeffrey Wang, Roger Karam