Abstract: An aircraft having an augmented reality flight control system integrated with and operable from the pilot seat and an associated pilot headgear unit, wherein the flight control system is supplemented by flight-assisting artificial intelligence and geo-location systems is presented. The present disclosure includes an augmented reality flight control system incorporating real-world objects with virtual elements to provide relevant data to a pilot during aircraft flight. A translucent substrate is disposed in the pilot's field of view such that the pilot can see therethrough, and observe virtual elements displayed on the substrate. The system includes a headgear that is worn by the pilot. A flight assistance module is configured to receive data related to the aircraft and provide predictive assistance to the pilot during flight based on the received data based in part on a pilot profile having preferences related to the pilot.

Abstract: A method includes detecting a request for a battery charge, receiving multiple battery parameters representative of battery charging history, determining a charging parameter to increase battery life as a function of the multiple battery parameters, and charging the battery in accordance with the charging parameter.

Abstract: In an embodiment, a method includes: adjusting a first flight control device of a rotorcraft to control flight around a first axis of the rotorcraft, the first flight control device exercising flight control authority around the first axis of the rotorcraft; detecting a failure of the first flight control device; transitioning at least a portion of the flight control authority around the first axis of the rotorcraft from the first flight control device to a second flight control device of the rotorcraft, the transitioning being performed automatically in response to detecting the failure of the first flight control device; and adjusting the second flight control device to control flight around the first axis of the rotorcraft, the second flight control device being adjusted by a first control process when the rotorcraft is in a first flight mode, the second flight control device being adjusted by a second control process when the rotorcraft is in a second flight mode.

Abstract: A system, device, and method for predicting an active set of compounds that bind to a biomolecular target is disclosed. The system and device contain modules allowing for the prediction of an active set of compounds. A core identification module can identify the core of an initial lead compound. A core hopping module is used to identify potential lead compounds having different cores compared to the core of an initial lead compound. A scoring module can use computational techniques to calculate the relative binding free energy of each identified potential lead compound. An activity prediction module can use the relative binding free energy calculations to predict an active set of compounds that bind to the biomolecular target. Empirical analysis can be used to inform the accuracy and completeness of the predicted active set of compounds.

Abstract: An apparatus includes a battery having a battery monitoring unit (BMU) and an outer casing, and a resistance measuring device coupled to the outer casing. The battery monitoring unit and the resistance measuring device monitoring a change in surface temperature on the casing of the battery during a charging or discharging of the battery, compare the change in surface temperature with an expected change in surface temperature during the charging or discharging of the battery, and determine that a swelling of the battery has occurred when the change in surface temperature is less than the expected change in the surface temperature.

Abstract: An amount of power that is provided to a load is measured. The load is coupled to a battery backup unit (BBU) or an uninterruptable power supply (UPS). The amount of power is stored into a history of power draw for the load. The history of power draw is used to determine a time period or a situation when additional power is required by the load or reduced energy can be provided to the load. The charge of the BBU or the UPS is increased or reduced prior to the time period or the situation when the additional power is required by the load or the reduced energy can be provided to the load.

Abstract: Systems and methods are provided to stop both external and internal fraud, ensure correct actions are being followed, and information is available to fraud teams for investigation. The system includes components that can address: 1) behavioral analytics (ANI reputation, IVR behavior, account activity)—this gives a risk assessment event before a call gets to an agent; 2) fraud detection—the ability to identify, in real time, if a caller is part of a fraudster cohort' and alert the agent and escalate to the fraud team; 3) identity authentication—the ability to identify through natural language if the caller is who they say they are; and 4) two factor authentication—the ability to send a text message to the caller and automatically process the response and create a case in the event of suspected fraud.

Abstract: A helmet is provided, which includes a helmet shell and a fastening assembly. The fastening assembly has a mounting fixture releasably connected to the helmet shell and a release mechanism operatively connectable to the mounting fixture, where connection of the release mechanism to the mounting fixture secures the mounting fixture to the helmet shell, and disconnection of the release mechanism from the mounting fixture enables disconnection of the mounting fixture from the helmet shell.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Abstract: A tool for securing a clamp having a band and a clip is provided. The tool includes a base member and a first handle coupled to the base member. A cinching handle is rotationally coupled to the base member adjacent the first handle. A crimping handle is rotationally coupled to the base member adjacent the first handle opposite the cinching handle. A holding means is provided for holding the clip. A tensioning means is provided for moving a tab end portion of the band through the clip, the tensioning means being operably coupled to the cinching handle. A crimping means is provided for locking the clip to the band, the crimping means being operably coupled to the crimping handle. A severing means is provided for severing the tab end portion from the band, the severing means being operably coupled to the crimping handle.

Abstract: The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for inhibiting kinase activity, and for treating cancer.

Abstract: An amount of power that is provided to a load is measured. The load is coupled to a battery backup unit (BBU) or an uninterruptable power supply (UPS). The amount of power is stored into a history of power draw for the load. The history of power draw is used to determine a time period or a situation when additional power is required by the load or reduced energy can be provided to the load. The charge of the BBU or the UPS is increased or reduced prior to the time period or the situation when the additional power is required by the load or the reduced energy can be provided to the load.

Abstract: The preparedness of a backup power supply is enhanced by receiving data from a source external to the backup power supply. It is determined from the data that there is a threat of power interruption. The charge on the backup power supply is varied based on the threat of power interruption.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of Cbl-b-mediated disorders.

Abstract: A method of verifying the destination of a transaction between nodes in a network includes receiving transaction information corresponding to a transaction between the nodes, where the transaction information comprises a unique destination identifier and a destination name and where the unique destination identifier defines a destination account of the transaction; obtaining from a storage unit a set of names used in previous transactions to that destination account; determining at least one disparity value between the destination name and the set of names; and producing a destination verification value based on the at least one disparity value, wherein the destination verification value is used to verify whether the transaction between nodes should proceed.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Abstract: The present disclosure relates to a method for at least one of forming a part or modifying a part, and a system therefor. The method involves initially providing a planar structure having a first material layer disposed on a second material layer. A lithographic operation including greyscale printing is performed to produce a resist material layer on the first material layer, with the resist material layer having a predetermined three-dimensional pattern extending along X, Y and Z axes, with features helping to define the three-dimensional pattern having differing dimensions along the Z axis, and which acts as a mask.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.