Patents by Inventor John M. McCoy

John M. McCoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microorganisms and methods for producing sialylated and N-acetylglucosamine-containing oligosaccharides
    Patent number: 10415069
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 17, 2019
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy
  • USE OF PURIFIED 2'-FUCOSYLLACTOSE, 3-FUCOSYLLACTOSE AND LACTODIFUCOTETRAOSE AS PREBIOTICS
    Publication number: 20190255083
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 22, 2019
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • SIALYLTRANSFERASES AND USES THEREOF
    Publication number: 20190218582
    Abstract: Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.
    Type: Application
    Filed: December 14, 2018
    Publication date: July 18, 2019
    Inventors: Srikrishnan Mallipeddi, Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • Use of purified 2?-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
    Patent number: 10286001
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: May 14, 2019
    Assignees: Glycosyn LLC, Trustees of Boston College
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
    Patent number: 10273516
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: April 30, 2019
    Assignee: Glycosyn LLC
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN ENGINEERED BACTERIA
    Publication number: 20180251771
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: May 15, 2018
    Publication date: September 6, 2018
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Biosynthesis of human milk oligosaccharides in engineered bacteria
    Patent number: 9970018
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: May 15, 2018
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Biosynthesis Of Human Milk Oligosaccharides In Engineered Bacteria
    Publication number: 20180080034
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: September 21, 2017
    Publication date: March 22, 2018
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Microorganisms and Methods for Producing Sialylated and N-Acetylglucosamine-Containing Oligosaccharides
    Publication number: 20180057849
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: September 11, 2017
    Publication date: March 1, 2018
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy
  • Alpha (1,3) Fucosyltransferases For Use In The Production of Fucosylated Oligosaccharides
    Publication number: 20170306373
    Abstract: The invention relates to methods and compositions for the production of fucosylated oligosaccharides.
    Type: Application
    Filed: September 9, 2015
    Publication date: October 26, 2017
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • Biosynthesis Of Human Milk Oligosaccharides In Engineered Bacteria
    Publication number: 20170268010
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: February 24, 2017
    Publication date: September 21, 2017
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Microorganisms and methods for producing sialylated and N-acetylglucosamine-containing oligosaccharides
    Patent number: 9758803
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 12, 2017
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy
  • Biosynthesis Of Human Milk Oligosaccharides In Engineered Bacteria
    Publication number: 20170226547
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: February 24, 2017
    Publication date: August 10, 2017
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • USE OF PURIFIED 2?-FUCOSYLLACTOSE, 3-FUCOSYLLACTOSE AND LACTODIFUCOTETRAOSE AS PREBIOTICS
    Publication number: 20170136049
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Alpha (1,2) Fucosyltransferases Suitable for Use in the Production of Fucosylated Oligosaccharides
    Publication number: 20170081689
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: May 11, 2015
    Publication date: March 23, 2017
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • Alpha (1,2) Fucosyltransferase Syngenes For Use in the Production of Fucosylated Oligosaccharides
    Publication number: 20170081353
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: May 14, 2015
    Publication date: March 23, 2017
    Inventors: John M. McCoy, Matthew Ian Heidtman, Massimo Merighi
  • Biosynthesis of human milk oligosaccharides in engineered bacteria
    Patent number: 9587241
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: March 7, 2017
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Use of purified 2?-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
    Patent number: 9567361
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: February 14, 2017
    Assignees: Glycosyn LLC, Trustees of Boston College
    Inventors: David S Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Biosynthesis of human milk oligosaccharides in engineered bacteria
    Patent number: 9453230
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: September 27, 2016
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Microorganisms and Methods for Producing Sialylated and N-Acetylglucosamine-Containing Oligosaccharides
    Publication number: 20160024543
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy