Patents by Inventor John R. White
John R. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8858561Abstract: An orthopedic apparatus includes an alignment guide attachable to one of a femoral joint surface of a femur of a patient. The alignment guide has a patient-specific three-dimensional engagement surface, and at least one guiding portion defining a guiding passage. The engagement surface anatomically matches a corresponding portion of the femoral joint surface.Type: GrantFiled: June 18, 2009Date of Patent: October 14, 2014Assignee: Blomet Manufacturing, LLCInventors: John R. White, Kurt Schmidt, Troy W. Hershberger, Thomas C. Raish, Ryan J. Schoenefeld, William J. Hamman, Jason D. Meridew, Tyler D. Witt, Robert Metzger, J. Scott Deming, Tim Clijmans, Frederik Gelaude
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Patent number: 8828384Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.Type: GrantFiled: June 26, 2013Date of Patent: September 9, 2014Assignee: GlaxoSmithKline LLCInventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Pual Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
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Patent number: 8696757Abstract: A prosthetic device for replacement of a first pelvic portion of a pelvis of a patient opposite to a second pelvic portion relative to a median plane includes an acetabular component a flange component and a pubis component. The acetabular component has a first connecting portion and a second connecting portion at an angle relative to the first connecting portion, the angle selected for a corresponding anatomy of the patient. The flange component is coupled to the first connecting portion and configured to attach to a healthy pelvic portion on a same side of the median plane from the first pelvic portion. The pubis component is connected to the second connecting portion of the acetabular component and having a clamping portion configured to attach to a healthy pubis bone on an opposite side of the median plane from the first pelvic portion.Type: GrantFiled: October 31, 2011Date of Patent: April 15, 2014Assignee: Biomet Manufacturing, LLCInventors: David R. Brown, John R. White, Mark A. Bollinger, Brian M. May
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Publication number: 20140094816Abstract: A method for inserting an acetabular implant into the acetabulum of a patient. The method includes engaging a patient-specific surface of acetabular alignment guide to a complementary rim surface and periacetabular area of a patient. A plurality of alignment pins are inserted through corresponding alignment apertures of the acetabular alignment guide and into the periacetabular area of the patient. The acetabular alignment guide is removed without removing the alignment pins from the patient. An alignment adapter is coupled to an acetabular inserter over the alignment pins and an acetabular implant is implanted using the acetabular inserter.Type: ApplicationFiled: December 9, 2013Publication date: April 3, 2014Applicant: Biomet Manufacturing, LLCInventors: John R. WHITE, Lance D. PERRY, Aaron P. SMITH, Jason D. MERIDEW, Bryan MORRISON, W. Jason SLONE, Tyler D. WITT, Mark A. BOLLINGER, Robert METZGER
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Publication number: 20140074251Abstract: A method for centering a stem of an implant at an implantation site. The method includes implanting at the implantation site the implant having a sleeve rigidly mounted to the stem of the implant, the stem extends through an interior area of the sleeve. The method further includes compressing the sleeve by applying force to the sleeve to expand a mesh portion of the sleeve outward from the stem and into engagement with sidewalls of the implantation site to thereby center the stem at the implantation site.Type: ApplicationFiled: November 18, 2013Publication date: March 13, 2014Applicant: Biomet Manufacturing, LLCInventors: Jason D. MERIDEW, John R. WHITE, Mark A. BOLLINGER
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Publication number: 20140052270Abstract: An implant for a femoral head of a patient. The implant includes a shell implantable on the femoral head of the patient and correcting a defect of the femoral head. The shell is designed preoperatively to have a patient-specific first surface for articulation with the patient's acetabulum and a patient-specific periphery mateable with a periphery of the defect. The shell caps the defect and the first surface of the shell is continuous to a remaining healthy surface of the femoral head. The defect can be a bone defect, a cartilage defect or a combination thereof.Type: ApplicationFiled: October 28, 2013Publication date: February 20, 2014Applicant: Biomet Manufacturing, LLCInventors: Tyler D. Witt, Jason D. Meridew, John R. White, Troy W. Hershberger, Robert Metzger
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Publication number: 20140018934Abstract: A method for preparing a femoral neck for receiving a neck implant includes resecting a femoral head from a femoral neck of a patient according to a pre-operative patient-specific plan. The method also includes removing only cancellous bone from the femoral neck and proximal femoral bone of the patient using a patient-specific broach. The patient-specific broach has a three-dimensional cutting surface matching as a negative mold a cortical/cancellous bone interface surface of the femoral neck of the patient.Type: ApplicationFiled: September 16, 2013Publication date: January 16, 2014Applicant: Biomet Manufacturing, LLCInventors: Jason D. MERIDEW, John R. White, Robert Metzger
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Publication number: 20140010807Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.Type: ApplicationFiled: June 26, 2013Publication date: January 9, 2014Inventors: Stephanie Jane CLEGG, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
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Patent number: 8603180Abstract: An acetabular device includes a patient-specific acetabular alignment guide including a bone engagement surface. The bone engagement surface has a first portion configured and shaped to be conforming and complementary to an acetabular rim surface and a second portion configured and shaped to be conforming and complementary to a periacetabular area of an acetabulum of a patient. The acetabular alignment guide includes a plurality of guiding formations extending through the second portion for guiding a plurality of alignment pins therethrough. The bone engagement surface and the plurality of guiding formations are prepared from a three-dimensional model of the acetabulum of the specific patient reconstructed pre-operatively from a scan of the patient.Type: GrantFiled: May 19, 2011Date of Patent: December 10, 2013Assignee: Biomet Manufacturing, LLCInventors: John R. White, Lance D. Perry, Aaron P. Smith, Jason D. Meridew, Bryan Morrison, W Jason Slone, Tyler D. Witt, Mark A. Bollinger, Robert Metzger
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Patent number: 8585770Abstract: An implant sleeve operable to center an implant at an implantation site. The implant sleeve includes a proximal end, a distal end, an annular sidewall, a mesh portion of the annular sidewall, and an interior area. The annular sidewall is between the proximal end and the distal end. The mesh portion defines a plurality of openings in the annular sidewall. The interior area is defined by the annular sidewall and is configured to receive a stem of the implant. A longitudinal axis of the implant sleeve extends along an axial center of the interior area. In response to force applied to the implant sleeve, the implant sleeve compresses and the mesh portion expands outward from the longitudinal axis.Type: GrantFiled: July 12, 2011Date of Patent: November 19, 2013Assignee: Biomet Manufacturing, LLCInventors: Jason D. Meridew, John R. White, Mark A. Bollinger
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Patent number: 8568487Abstract: A patient-specific acetabular resection guide includes a dome-shaped surface bounded by a periphery. The dome-shaped surface is a three-dimensional patient-specific surface designed to anatomically match and be received into an acetabulum of the patient, based on a three-dimensional image of a hip joint of the patient reconstructed from a medical scan of the hip joint. The resection guide includes a plurality of guiding formations defined on the resection guide and having patient-specific shapes and orientations for guiding corresponding osteotomies relative to the acetabulum for correcting hip dysplasia.Type: GrantFiled: December 23, 2010Date of Patent: October 29, 2013Assignee: Biomet Manufacturing, LLCInventors: Tyler D. Witt, Jason D. Meridew, John R. White, Troy W. Hershberger, Robert Metzger
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Publication number: 20130282132Abstract: An orthopedic implant includes a first portion including at least one feature modified to be patient-specific and match the anatomy of a specific patient from a three-dimensional digital image of a patient's joint using computer modeling. The orthopedic implant includes a non-custom inner bone-engaging surface including a plurality of planar surfaces configured for engagement with non-custom bone cuts.Type: ApplicationFiled: June 21, 2013Publication date: October 24, 2013Inventors: John R. WHITE, Robert METZGER, Keith R. BEREND
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Publication number: 20130245780Abstract: Disclosed is a system for replacing a portion of cartilage in an acetabulum. A prosthesis can be positioned within an acetabulum to form a portion of the articulation surface within the acetabulum and to articulate with a femoral bone. For example, an acetabular prosthesis can be implanted to articulate with the natural femoral head.Type: ApplicationFiled: May 10, 2013Publication date: September 19, 2013Applicant: BIOMET MANUFACTURING CORP.Inventors: Jason D. MERIDEW, John R. WHITE
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Patent number: 8535387Abstract: A method for preparing a femoral neck for receiving a neck implant includes obtaining image data of a proximal femoral bone and femoral neck of a patient by a medical imaging method and constructing a three-dimensional image model of the proximal femoral bone and neck of the patient using the image data. The method further includes identifying a three-dimensional cortical boundary surface at an interface between cortical and cancellous bone of the patient using the image model. A patient-specific broach having a three-dimensional cutting surface closely matching and complementary to the cortical boundary surface of the patient using the image model is designed and manufactured.Type: GrantFiled: March 7, 2011Date of Patent: September 17, 2013Assignee: Biomet Manufacturing, LLCInventors: Jason D. Meridew, John R. White, Robert Metzger
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Patent number: 8496932Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.Type: GrantFiled: April 16, 2008Date of Patent: July 30, 2013Assignee: GlaxoSmithKlineInventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
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Patent number: 8486150Abstract: An orthopedic implant includes a first portion including at least one feature modified to be patient-specific and match the anatomy of a specific patient from a three-dimensional digital image of a patient's joint using computer modeling. The orthopedic implant includes a non-custom inner bone-engaging surface including a plurality of planar surfaces configured for engagement with non-custom bone cuts.Type: GrantFiled: April 7, 2011Date of Patent: July 16, 2013Assignee: Biomet Manufacturing Corp.Inventors: John R. White, Robert Metzger, Keith R. Berend
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Publication number: 20130156779Abstract: The present disclosure relates to antigen binding proteins, such as antibodies, that bind to HER3, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present disclosure also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with breast cancer, ovarian cancer, prostate cancer, bladder cancer, pancreatic, gastric, melanoma and other cancers that overexpress HER3.Type: ApplicationFiled: September 2, 2011Publication date: June 20, 2013Inventors: Neil James Clarke, Kyung Oh Johanson, Zdenka Ludmila Jonak, Alexander H. Taylor, Christopher B. Hopson, Stephen H. Trulli, Zdenka Haskova, Judithann M. Lee, John R. White, Yu Xue
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Patent number: 8435483Abstract: A method for producing ammonium metatungstate from ammonium paratungstate includes preparing an ammonium paratungstate mixture including solid ammonium paratungstate and water. The mixture is contacted with a cation exchange material to lower a pH of the mixture to a pH range wherein metatungstate ion is stable and an insoluble tungstic acid is not formed. The pH of the mixture may be maintained in the pH range until the ammonium paratungstate mixture is converted into an ammonium metatungstate solution.Type: GrantFiled: August 4, 2010Date of Patent: May 7, 2013Assignee: TDY Industries, LLCInventor: John R. White
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Publication number: 20130086860Abstract: The present invention relates generally to modular demountable wall systems and more particularly, to a flexible and versatile demountable wall system for where control of air pressure and contaminants may be required.Type: ApplicationFiled: October 7, 2011Publication date: April 11, 2013Applicant: CONCEPTS TO SOLUTIONS INC.Inventors: John Vernon SOLOMON, John R. WHITE, Forrest C. CURRY, John RYDALL
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Publication number: 20130018482Abstract: An implant sleeve operable to center an implant at an implantation site. The implant sleeve includes a proximal end, a distal end, an annular sidewall, a mesh portion of the annular sidewall, and an interior area. The annular sidewall is between the proximal end and the distal end. The mesh portion defines a plurality of openings in the annular sidewall. The interior area is defined by the annular sidewall and is configured to receive a stem of the implant. A longitudinal axis of the implant sleeve extends along an axial center of the interior area. In response to force applied to the implant sleeve, the implant sleeve compresses and the mesh portion expands outward from the longitudinal axis.Type: ApplicationFiled: July 12, 2011Publication date: January 17, 2013Applicant: Biomet Manufacturing Corp.Inventors: Jason D. Meridew, John R. White, Mark A. Bollinger