Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.

Abstract: The invention relates to the detection of non-metabolized vitamin D. In a particular aspect, the invention relates to methods for detecting underivatized non-metabolized vitamin D by mass spectrometry.

Abstract: In one embodiment, a method includes generating, at a multi-view display, a first content to be viewed at a first angle and a second content to be viewed at a second angle. The first content and the second content are displayed simultaneously. The method also includes receiving, at a touch-screen panel coupled to the multi-view display, a first plurality of capacitive signals. The method then generates, by the touch-screen panel, a first touch-screen panel heatmap based on the received first plurality of capacitive signals. The method afterwards determines, based on the first touch-screen panel heatmap, whether a first user input is received with respect to the first content or the second content. The method then assigns, based on determining the first user input corresponds to either the first content or the second content, the first user input to the first content or the second content.

Abstract: A system and method for a hybrid multimode input device includes a multimode input device capable of a two-dimensional (2D) mode of operation and a three-dimensional (3D) mode of operation. The device includes a two-dimensional (2D) position sensor, a three-dimensional (3D) position sensor, and a processor. The processor is configured to enter a 3D input mode when the processor detects that the input device is in a first orientation, and enter a 2D input mode when the processor detects that the input device is in a second orientation. The 2D input mode is configured to provide 2D position data to a connected computer system, and wherein the 3D input mode is configured to provide 3D position data to the connected computer system.

Abstract: Methods are described for measuring the amount of C peptide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying C peptide in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

Abstract: A method for controlling content rendering by a multi-view, directionally dependent display includes defining a first display as a first pixel of a pixelated array of the multi-view display, the first display associated with a first viewing angle relative to a first axis; and defining a second display as a second pixel of the pixelated array, the second display. The method includes controlling chromatic properties of the first pixel by applying a filter based on a rendering of first content to be displayed. The method also includes controlling chromatic properties of the second pixel by applying a filter based on a rendering of second content to be displayed; and controlling points of incidence of light from the first and second pixel relative to an optical multiplexer thereby changing the directionality of the multi-view, directionally dependent display.

Abstract: A method includes determining one or more controlled viewpoints of a multi-user display which includes a pixelated array and a directional multiplexer, and for each viewpoint of the one or more controlled viewpoints, determining first content to be displayed to the controlled viewpoint according to a visibility criterion. The method further includes, for each viewpoint of the one or more controlled viewpoints, determining a first subset of pixels of the pixelated array whose visibility from the controlled viewpoint satisfies the visibility criterion, and rendering the first content to be displayed on the first subset of pixels of the pixelated array.

Abstract: Methods are provided for detecting the amount of one or more HRT panel analytes (i.e., estrone (E1), estrone sulfate (E1s), 17?-estradiol (E2a), 17?-estradiol (E2b), estradiol sulfate (E2s), estriol (E3), equilin (EQ), 17?-dihydroequilin (EQa), 17?-dihydroequilin (EQb), Equilenin (EN), 17?-dihydroequilenin (ENa), 17?-dihydroequilenin (ENb), and ?8,9-dehydroestrone (dE1)) in a sample by mass spectrometry. The methods generally involve ionizing one or more HRT panel analytes in a sample and quantifying the generated ions to determine the amount of one or more HRT panel analytes in the sample. In methods where amounts of multiple HRT panel analytes are detected, the amounts of multiple analytes are detected in the same sample injection.

Abstract: Provided are methods for determining the amount of tamoxifen and its metabolites in a sample by mass spectrometry. In some aspects, the methods provided herein determine the amount of norendoxifen. In some aspects, the methods provided herein determine the amount of norendoxifen and tamoxifen. In some aspects, the methods provided herein determine the amount of norendoxifen and other tamoxifen metabolites. In some aspects, the methods provided herein determine the amount of tamoxifen, norendoxifen, and other tamoxifen metabolites.

Abstract: A method of rendering content for display on a multi-view display includes assigning a first display to a first pixel of a pixelated array, with a plurality of pixels periodically spaced along a first axis, the first display associated with a first viewing angle relative to the first axis. The method includes assigning a second display to a second pixel of the pixelated array, display associated with a second viewing angle relative to the first axis. The method further includes controlling a filter value of the first pixel based on a rendering of first content for display, and controlling a filter value of the second pixel based on a rendering of second content for display. The first viewing angle belongs to a first range of viewing angles of an optical multiplexer disposed in front of the pixelated array.

Abstract: Methods are described for measuring the amount of C peptide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying C peptide in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

Abstract: Methods are described for determining the amount of insulin in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying insulin in a biological sample utilizing purification methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.

Abstract: The invention relates to the detection of non-metabolized vitamin D. In a particular aspect, the invention relates to methods for detecting underivatized non-metabolized vitamin D by mass spectrometry.

Abstract: A method of rendering content for display on a multi-view display includes assigning a first display to a first pixel of a pixelated array, with a plurality of pixels periodically spaced along a first axis, the first display associated with a first viewing angle relative to the first axis. The method includes assigning a second display to a second pixel of the pixelated array, display associated with a second viewing angle relative to the first axis. The method further includes controlling a filter value of the first pixel based on a rendering of first content for display, and controlling a filter value of the second pixel based on a rendering of second content for display. The first viewing angle belongs to a first range of viewing angles of an optical multiplexer disposed in front of the pixelated array.

Abstract: A method includes determining one or more controlled viewpoints of a multi-user display which includes a pixelated array and a directional multiplexer, and for each viewpoint of the one or more controlled viewpoints, determining first content to be displayed to the controlled viewpoint according to a visibility criterion. The method further includes, for each viewpoint of the one or more controlled viewpoints, determining a first subset of pixels of the pixelated array whose visibility from the controlled viewpoint satisfies the visibility criterion, and rendering the first content to be displayed on the first subset of pixels of the pixelated array.

Abstract: An apparatus includes a backlight, a color filter disposed in front of the backlight along a viewing direction, wherein the color filter includes a plurality of pixels repeating at a first spacing along a first axis. The apparatus further includes a lenticular layer disposed in front of the backlight, the lenticular layer including a section of material having a first index of refraction, a first, substantially flat side, and a second side defining a lenticularly patterned cross section along the first axis, the lenticularly patterned cross section including lens elements repeating at a second spacing and directing light originating from the backlight in two or more directions.

Abstract: A system and method for a hybrid multimode input device includes a multimode input device capable of a two-dimensional (2D) mode of operation and a three-dimensional (3D) mode of operation. The device includes a two-dimensional (2D) position sensor, a three-dimensional (3D) position sensor, and a processor. The processor is configured to enter a 3D input mode when the processor detects that the input device is in a first orientation, and enter a 2D input mode when the processor detects that the input device is in a second orientation. The 2D input mode is configured to provide 2D position data to a connected computer system, and wherein the 3D input mode is configured to provide 3D position data to the connected computer system.

Abstract: Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydorxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.

Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.

Abstract: Methods are described for determining the amount of insulin in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying insulin in a biological sample utilizing purification methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.