Abstract: Annotations can be automatically added to a media presentation during playback of the presentation without a user having to manually interact with the playback device. The playback device determines whether an annotation is to be added to the media presentation based on characteristics of voice input received at the device, such as voice input signal strength or variances in the voice input signal strength. Characteristics of video input received at the device can be used to determine whether a user is speaking to the computing device as well. The device can handle a new annotation overlapping an existing annotation by either removing the existing annotation or by shifting the existing annotation until there is no more overlap. A media presentation can comprise multiple annotation tracks.

Abstract: A high speed powerboat hull (100) incorporating a tunnel ventilation channel (154) spanning between a starboard (160) and port (162) side of the hull (100). The hull (100) has a “V” shaped forward section. The ventilated tunnel (150) is provided as a recess having two substantially vertical sidewalls (152) arranged parallel to each other located along each of the two outer edges of the tunnel (150). The tunnel (150) is disposed longitudinally between the ventilated channel (154) and a transom (112). The ventilated tunnel (150) is in fluid communication with the ventilation channel (154). The hull (100) can further comprise at least one stepped hull section (122, 126).

Abstract: Social network notifications are described. In implementations, a notification is received at a client device from a social network service that includes content that is posted for access via the social network service and includes an identifier of an originator of the posting. The notification is output by the client device to include the content from the posting and the identifier of the originator of the posting.

Abstract: A housing structure has a frame structure 1 on which there are arranged via connecting elements 7 several optical elements 5 which are held in mounts 6 or structural modules 6?. The optical elements 5 are detachably connected to the frame structure 1 with their mounts 6 or structural modules 6? and connecting elements 7 in such a way that in the installed state they are integrated as bearing units in the frame structure 1.

Abstract: A housing structure has a frame structure 1 on which there are arranged via connecting elements 7 several optical elements 5 which are held in mounts 6 or structural modules 6?. The optical elements 5 are detachably connected to the frame structure 1 with their mounts 6 or structural modules 6? and connecting elements 7 in such a way that in the installed state they are integrated as bearing units in the frame structure 1.

Abstract: The invention relates to methods for predicting a clinical response to B-lymphocyte inhibiting or depleting therapies (BCIDT) using expression levels of genes of the Type I INF pathway. In another aspect, the invention relates to a method for evaluating a pharmacological effect of a treatment with B-lymphocyte inhibiting or depleting therapy.

Abstract: A method for removal of deposition on a radiation collector of a lithographic apparatus includes providing a gas barrier to an end of a radiation collector, thereby providing a radiation collector enclosure volume; providing a gas to the enclosure volume, the gas selected from a halogen containing gas and a hydrogen containing gas; and removing at least part of the deposition from the radiation collector. A lithographic apparatus includes a radiation collector; a circumferential hull enclosing the radiation collector; a gas barrier at an end of the radiation collector, thereby providing a radiation collector enclosure volume. The radiation collector is enclosed by the circumferential hull and the gas barrier. An inlet provides a gas to the radiation collector enclosure volume and an outlet removes a gas from the radiation collector enclosure volume.

Abstract: An exterior surface treatment system for treating surfaces in the open air subject to weathering includes a container. The container is formed of a water soluble material and defines an interior. The system includes a composition located in the interior, the composition including one or more biocides, the total proportion of the biocide or biocides in the composition being greater than 40% w/w.

Abstract: A variable resistance device and an abdominal exercise apparatus. The device includes at least first and second resilient stages to provide a combined resistance effect. The first resilient stage has a lower coefficient of elasticity than the second resilient stage. In this way, when a user lies on the base of the apparatus and pulls on the yoke a first resistance is experienced by virtue of thin cords until a strap reaches its full length and a second resistance is experienced by virtue of thick cords.

Abstract: The present invention provides compounds according to general Formula (I), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt of a prodrug thereof. More particularly, the present invention provides high affinity non-steroidal compounds which are agonists, partial agonists or antagonists of the progesterone receptor.

Abstract: A radiation system for generating a beam of radiation that defines an optical axis is provided. The radiation system includes a plasma produced discharge source for generating EUV radiation. The discharge source includes a pair of electrodes constructed and arranged to be provided with a voltage difference, and a system for producing a plasma between the pair of electrodes so as to provide a discharge in the plasma between the electrodes. The radiation system also includes a debris catching shield for catching debris from the electrodes. The debris catching shield is constructed and arranged to shield the electrodes from a line of sight provided in a predetermined spherical angle relative the optical axis, and to provide an aperture to a central area between the electrodes in the line of sight.

Abstract: A radiation system for generating a beam of radiation that defines an optical axis is provided. The radiation system includes a plasma produced discharge source for generating EUV radiation. The discharge source includes a pair of electrodes constructed and arranged to be provided with a voltage difference, and a system for producing a plasma between the pair of electrodes so as to provide a discharge in the plasma between the electrodes. The radiation system also includes a debris catching shield for catching debris from the electrodes. The debris catching shield is constructed and arranged to shield the electrodes from a line of sight provided in a predetermined spherical angle relative the optical axis, and to provide an aperture to a central area between the electrodes in the line of sight.

Abstract: A housing structure has a frame structure 1 on which there are arranged via connecting elements 7 several optical elements 5 which are held in mounts 6 or structural modules 6?. The optical elements 5 are detachably connected to the frame structure 1 with their mounts 6 or structural modules 6? and connecting elements 7 in such a way that in the installed state they are integrated as bearing units in the frame structure 1.

Abstract: Methods and apparatus are provided for communicating between a host and a peripheral. In one embodiment, a method comprises the steps: establishing, in a manner transparent to the host, a wireless data link between a wireless hub device and a wireless peripheral device coupled to the peripheral, the wireless hub device coupled to and configured to communicate with the host, wherein the host is configured to communicate with peripheral devices over a wireline link at a plurality of data rates when connected via the wireline link; and controlling a flow of data between the host and the wireless hub device so that the host is unaware of the wireless data link, wherein the data is to be communicated between the host and the peripheral.

Abstract: A lithographic apparatus includes a radiation system including a radiation source for the production of a radiation beam, and a contaminant trap arranged in a path of the radiation beam. The contaminant trap includes a plurality of foils or plates defining channels that are arranged substantially parallel to the direction of propagation of said radiation beam. The foils or plates can be oriented substantially radially with respect to an optical axis of the radiation beam. The contaminant trap can be provided with a gas injector which is configured to inject gas at least at two different positions directly into at least one of the channels of the contaminant trap.

Abstract: A contamination prevention system is constructed and arranged to prevent material from propagating with radiation into a lithographic apparatus. The contamination prevention system includes a rotatable carrier provided with a plurality of generally radially outwardly extending blades. The blades are constructed and arranged to absorb or deflect the material. The system also includes a stationary shaft, and a bearing constructed and arranged to rotate the rotatable carrier and the blades around the shaft. The rotatable carrier is provided with a space for at least partially receiving a portion of the shaft.

Abstract: Topical formulations comprising inhibitors of dihydropyrimidine dehydrogenase (DPD), thymidine phosphorylase (TP) and/or uridine phosphorylase (UP) enzyme inhibitors are provided for the treatment of hand-foot syndrome (HFS) in cancer patients undergoing treatment with 5-FU and 5-FU prodrugs.

Abstract: Chemically modified cyclic peptides comprising cell adhesion recognition (CAR) sequences are provided having improved properties, such as improved stability. Also provided are methods of making and using same.

Abstract: A prosthetic component assembly, such as an acetabular cup, includes a shell, a bearing positioner and a bearing. The shell and bearing positioner are configured to facilitate orienting the bearing positioner in multiple orientations relative to the shell and for securing the bearing positioner in a selected orientation of the multiple orientations relative to the shell. The bearing is configured to be received in the bearing positioner at multiple rotational orientations for optimal joint biomechanics. The bearing positioner is selected from among a plurality of lateralized positioners to accommodate the joint anatomy.

Abstract: A contamination prevention system is constructed and arranged to prevent material from propagating with radiation into a lithographic apparatus. The contamination prevention system includes a rotatable carrier provided with a plurality of generally radially outwardly extending blades. The blades are constructed and arranged to absorb or deflect the material. The system also includes a stationary shaft, and a bearing constructed and arranged to rotate the rotatable carrier and the blades around the shaft. The rotatable carrier is provided with a space for at least partially receiving a portion of the shaft.