Patents by Inventor Peter G. Klimko

Peter G. Klimko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOPICAL OCULAR ANALGESIC AGENTS
    Publication number: 20160089375
    Abstract: The topical ophthalmic use of certain 2,4-diamino-substituted 1,3-triazines for preventing or alleviating ocular pain in patients is disclosed. Topical ocular pharmaceutical composition are also disclosed.
    Type: Application
    Filed: October 9, 2015
    Publication date: March 31, 2016
    Inventors: Martha E. Gadd, Peter G. Klimko, Karen C. David, Kenneth C. Appell, Mark R. Hellberg
  • Topical ocular analgesic agents
    Patent number: 9187468
    Abstract: The topical ophthalmic use of certain 2,4-diamino-substituted 1,3-triazines for preventing or alleviating ocular pain in patients is disclosed. Topical ocular pharmaceutical composition are also disclosed.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: November 17, 2015
    Assignee: NOVARTIS AG
    Inventors: Martha E. Gadd, Peter G. Klimko, Karen C. David, Kenneth C. Appell, Mark R. Hellberg
  • OPHTHALMIC COMPOSITION WITH NITRIC OXIDE DONOR COMPOUND AND METHOD OF FORMING AND USING SAME
    Publication number: 20140371267
    Abstract: The present invention is directed to the provision of ophthalmic compositions such as multi-dose, topical, ophthalmic compositions. The compositions include a nitric oxide (NO) donor compound.
    Type: Application
    Filed: August 28, 2014
    Publication date: December 18, 2014
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Mark R. Hellberg, Peter G. Klimko, Jesse A. May, Suchismita Mohapatra
  • TOPICAL OCULAR ANALGESIC AGENTS
    Publication number: 20140228338
    Abstract: The topical ophthalmic use of certain 2,4-diamino-substituted 1,3-triazines for preventing or alleviating ocular pain in patients is disclosed. Topcial ocular pharmaceutical composition are also disclosed.
    Type: Application
    Filed: February 13, 2014
    Publication date: August 14, 2014
    Applicant: Novartis AG
    Inventors: Martha E. Gadd, Peter G. Klimko, Karen C. David, Kenneth C. Appell, Mark R. Hellberg
  • Method of Accelerating Corneal Wound Healing
    Publication number: 20140228430
    Abstract: The topical ophthalmic use of 5,6,7-trihydroxyheptanoic acid and analogs for the acceleration of corneal wound healing in humans, is disclosed.
    Type: Application
    Filed: January 16, 2014
    Publication date: August 14, 2014
    Applicant: Alcon Research, Ltd.
    Inventors: Daniel A. Gamache, Mark R. Hellberg, Peter G. Klimko, Kerry L. Markwardt, John M. Yanni, Eric C. Carlson
  • CONTROL OF INTRAOCULAR PRESSURE USING ALK5 MODULATION AGENTS
    Publication number: 20120115870
    Abstract: An ophthalmic pharmaceutical composition useful in the treatment of glaucoma and control of intraocular pressure comprising an effective amount of a selective modulator of ALK5 receptor activity is disclosed. Also disclosed is a method of treating glaucoma and controlling intraocular pressure comprising applying a therapeutically effective amount of a pharmaceutical composition comprising a selective modulator of ALK5 receptor activity to an affected eye of a patient.
    Type: Application
    Filed: January 11, 2012
    Publication date: May 10, 2012
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Debra L. Fleenor, Iok-Hou Pang, Allan R. Shepard, Mark R. Hellberg, Peter G. Klimko, Abbot F. Clark
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALLERGY
    Publication number: 20120015953
    Abstract: The present invention relates to compositions comprising an antagonist of the histamine H1 receptor and a compatible antagonist of the histamine H4 receptor. The antagonist compounds are selected to prevent the H4 receptor antagonist from interfering with the H1 receptor antagonist's suppression of acute phase allergic responses in a patient. The present invention also relates to compositions comprising a mast cell stabilizer and a compatible antagonist of the histamine H4 receptor.
    Type: Application
    Filed: July 14, 2011
    Publication date: January 19, 2012
    Inventors: Clay Beauregard, Peter G. Klimko, John M. Yanni, Daniel A. Gamache
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Patent number: 8067405
    Abstract: The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: November 29, 2011
    Assignee: Novartis AG
    Inventors: Peter G. Klimko, Robert J. Collier, Jr., Mark R. Hellberg
  • Method of treating ocular allergy
    Patent number: 8034839
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: October 11, 2011
    Assignee: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • METHOD OF ACCELERATING CORNEAL WOUND HEALING
    Publication number: 20110207809
    Abstract: The topical ophthalmic use of 5,6,7-trihydroxyheptanoic acid and analogs for the acceleration of corneal wound healing in humans, is disclosed.
    Type: Application
    Filed: February 25, 2011
    Publication date: August 25, 2011
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Eric C. Carlson, Daniel A. Gamache, Mark R. Hellberg, Peter G. Klimko, Kerry L. Markwardt, John M. Yanni
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Patent number: 8003635
    Abstract: The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: August 23, 2011
    Assignee: Novartis AG
    Inventors: Peter G. Klimko, Robert J. Collier, Jr., Mark R. Hellberg
  • CONTROL OF INTRAOCULAR PRESSURE USING ALK5 MODULATION AGENTS
    Publication number: 20110160210
    Abstract: An ophthalmic pharmaceutical composition useful in the treatment of glaucoma and control of intraocular pressure comprising an effective amount of a selective modulator of ALK5 receptor activity is disclosed. Also disclosed is a method of treating glaucoma and controlling intraocular pressure comprising applying a therapeutically effective amount of a pharmaceutical composition comprising a selective modulator of ALK5 receptor activity to an affected eye of a patient.
    Type: Application
    Filed: March 8, 2011
    Publication date: June 30, 2011
    Applicant: ALCON, INC.
    Inventors: Debra L. Fleenor, Iok-Hou Pang, Allan R. Shapard, Mark R. Hellberg, Abbot F. Clark, Peter G. Klimko
  • METHOD OF TREATING DRY EYE DISORDERS AND UVEITIS
    Publication number: 20110130451
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs are disclosed for the treatment of dry eye disorders and uveitis.
    Type: Application
    Filed: February 8, 2011
    Publication date: June 2, 2011
    Applicant: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Daniel A. Gamache
  • Superoxide Dismutase Mimics For The Treatment Of Optic Nerve And Retinal Damage
    Publication number: 20110105453
    Abstract: Methods for preventing and treating damage to the optic nerve and/or retina by the use of SOD mimics, particularly pentaazacycle Mn(II) complex SOD mimics, are disclosed.
    Type: Application
    Filed: December 17, 2010
    Publication date: May 5, 2011
    Applicant: ALCON, INC.
    Inventor: Peter G. Klimko
  • Method of treating dry eye disorders and uveitis
    Patent number: 7923471
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs are disclosed for the treatment of dry eye disorders and uveitis.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: April 12, 2011
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Daniel A. Gamache
  • 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES
    Publication number: 20110082200
    Abstract: Compositions containing 5,6,7-trihydroxyheptanoic acid and analogs and their use for treating posterior segment ocular diseases and diseases characterized by cellular hyperproliferation or angiogenesis, are disclosed.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 7, 2011
    Applicant: ALCON, INC.
    Inventors: Peter G. KLIMKO, Mark R. HELLBERG, David P. BINGAMAN, Daviel A. GAMACHE
  • 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses
    Patent number: 7879905
    Abstract: Compositions containing 5,6,7-trihydroxyheptanoic acid and analogs and their use for treating posterior segment ocular diseases and diseases characterized by cellular hyperproliferation or angiogenesis, are disclosed.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: February 1, 2011
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg, David P. Bingaman, Daniel A. Gamache
  • Superoxide dismutase-2 expression for glaucoma diagnosis
    Patent number: 7807363
    Abstract: The present invention concerns a method for diagnosing or monitoring elevated intraocular pressure or glaucoma in a patient comprising providing a biological sample from the patient and measuring the expression level of a superoxide dismutase-2 (SOD-2) gene in the biological sample. The present invention also concerns methods for treating glaucoma or elevated intraocular pressure in a patient comprising administering to a patient an effective amount of an agent that modulates SOD-2 expression or SOD-2 activity.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: October 5, 2010
    Assignee: Alcon Research, Ltd.
    Inventors: Wan-Heng Wang, Loretta Graves McNatt, Abbot F. Clark, Peter G. Klimko
  • SUPEROXIDE DISMUTASE MIMICS FOR THE TREATMENT OF OCULAR DISORDERS AND DISEASES
    Publication number: 20100204194
    Abstract: The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: April 23, 2010
    Publication date: August 12, 2010
    Applicant: ALCON, INC.
    Inventors: Peter G. Klimko, Robert J. Collier, JR., Mark R. Hellberg
  • OPHTHALMIC COMPOSITION WITH NITRIC OXIDE DONOR COMPOUND AND METHOD OF FORMING AND USING SAME
    Publication number: 20100197702
    Abstract: The present invention is directed to the provision of ophthalmic compositions such as multi-dose, topical, ophthalmic compositions. The compositions include a nitric oxide (NO) donor compound.
    Type: Application
    Filed: January 27, 2010
    Publication date: August 5, 2010
    Inventors: Mark R. Hellberg, Peter G. Klimko, Jesse A. May, Suchismita Mohapatra