Patents by Inventor Peter G. Klimko

Peter G. Klimko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of proteasome inhibitors to treat dry eye disorders
    Patent number: 6740674
    Abstract: Proteasome inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: May 25, 2004
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg
  • Histone deacetylase inhibitors for the treatment of ocular neovascular or edematous disorders and diseases
    Publication number: 20040092558
    Abstract: Ophthalmic compositions containing HDAC inhibitors and their use for treating ocular neovascular or edematous diseases and disorders are disclosed.
    Type: Application
    Filed: October 30, 2003
    Publication date: May 13, 2004
    Applicant: Alcon, Inc.
    Inventors: Peter G. Klimko, David P. Bingaman
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6723748
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: April 20, 2004
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke
  • Use of epothilones and analogs in conjunction with ophthalmic surgery
    Publication number: 20040058899
    Abstract: A method of use is disclosed for preventing or retarding posterior capsular opacification or scar formation following ophthalmic surgery by treatment of the surgical site with epothilones and analogs thereof.
    Type: Application
    Filed: November 6, 2002
    Publication date: March 25, 2004
    Inventor: Peter G. Klimko
  • 15-fluoro prostaglandins as ocular hypotensives
    Patent number: 6680339
    Abstract: 15-fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: January 20, 2004
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
    Publication number: 20030236305
    Abstract: Hydroxyeicosatetraenoic acid esters and methods of their use in treating dry eye disorders are disclosed.
    Type: Application
    Filed: April 4, 2003
    Publication date: December 25, 2003
    Inventors: Peter G. Klimko, Mark R. Hellberg, John R. Falck, Raymond E. Conrow
  • 15-fluoro prostaglandins as ocular hypotensives
    Patent number: 6649653
    Abstract: 15-Fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: November 18, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • Lipoxin A4 and its analogs for the treatment of dry eye
    Patent number: 6645978
    Abstract: Ophthalmic compositions containing Lipoxin A4 and its analogs and methods of their use for treating dry eve are disclosed.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: November 11, 2003
    Assignee: Alcon, Inc.
    Inventors: Daniel A. Gamache, Gustav Graff, Mark R. Hellberg, Peter G. Klimko, John M. Yanni
  • 6-Keto prostaglandin F1&agr; and analogs for treating dry eye
    Patent number: 6576663
    Abstract: Compositions and methods for the treatment of dry eye and related diseases utilizing 6-keto-PGF1&agr; and its analogs are disclosed.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: June 10, 2003
    Assignee: Alcon, Inc.
    Inventor: Peter G. Klimko
  • Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
    Patent number: 6552084
    Abstract: Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders are disclosed.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: April 22, 2003
    Assignee: Alcon Universal Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, John R. Falck, Raymond E. Conrow
  • Prostaglandin E agonists for treatment of glaucoma
    Patent number: 6545045
    Abstract: This application relates to compositions and methods for the treatment of glaucoma and/or ocular hypertension in mammals utilizing prostaglandin E receptor agonists.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: April 8, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, Najam A. Sharif, Brenda W. Griffin
  • Use of proteasome inhibitors to treat dry eye disorders
    Publication number: 20030008910
    Abstract: Proteasome inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
    Type: Application
    Filed: May 17, 2002
    Publication date: January 9, 2003
    Applicant: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg
  • 15-fluoro prostaglandins as acular hypotensives
    Publication number: 20020151587
    Abstract: 15-fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Application
    Filed: March 18, 2002
    Publication date: October 17, 2002
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • Prostaglandin E receptor agonists for treatment of dry eye
    Patent number: 6462080
    Abstract: The present invention relates to use of prostaglandin E receptor agonists and partial agonists to stimulate mucin secretion to treat dry eye, keratoconjunctivitis, Sjogren's syndrome and related ocular surface diseases.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: October 8, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Peter G. Klimko
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Patent number: 6458853
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: October 1, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Gustav Graff, Peter G. Klimko
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Patent number: 6458854
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: October 1, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Gustav Graff, Peter G. Klimko
  • 6-Keto prostaglandin F1alpha and analogs for treating dry eye
    Publication number: 20020137793
    Abstract: The invention relates to compositions and methods for the treatment of dry eye and related diseases utilizing 6-keto-PGF1&agr; and its analogs, according to formula (I); wherein A,B,D,Q9, Q11, R1, X and Y have the meanings given in the description. Some of these compounds are novel.
    Type: Application
    Filed: March 23, 2001
    Publication date: September 26, 2002
    Inventor: Peter G. Klimko
  • Heteroatom-interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use
    Patent number: 6441035
    Abstract: Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: August 27, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Raymond E. Conrow, Peter G. Klimko
  • Heteroatom-interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use
    Patent number: 6436994
    Abstract: Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: August 20, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Raymond E. Conrow, Peter G. Klimko
  • 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use
    Patent number: 6437160
    Abstract: 3-heteroatom substituted and two carbon homologs of 15-HETE, and their derivatives, compositions and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: August 20, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Gustav Graff