Patents by Inventor Peter G. Klimko

Peter G. Klimko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 13-Aza prostaglandins for the treatment of glaucoma and ocular hypertension
    Patent number: 6417228
    Abstract: 13-Aza analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: October 29, 1999
    Date of Patent: July 9, 2002
    Assignee: Alcon Manufacturing, Ltd..
    Inventor: Peter G. Klimko
  • 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use
    Publication number: 20020082286
    Abstract: 3-heteroatom substituted and two carbon homologs of 15-HETE, and their derivatives, compositions and methods of their use for treating dry eye are disclosed.
    Type: Application
    Filed: September 20, 2001
    Publication date: June 27, 2002
    Inventors: Peter G. Klimko, Mark R. Hellberg, Gustav Graff
  • Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
    Publication number: 20020035095
    Abstract: Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders are disclosed.
    Type: Application
    Filed: September 10, 2001
    Publication date: March 21, 2002
    Inventors: Peter G. Klimko, Mark R. Hellberg, John R. Falck, Raymond E. Conrow
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Patent number: 6353032
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Gustav Graff, Peter G. Klimko
  • 11-halo prostaglandins for the treatment of glaucoma or ocular hypertension
    Patent number: 6353000
    Abstract: A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 5, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Mark R. Hellberg, Peter G. Klimko, Paul W. Zinke
  • 15-Hydroxyeicosatetraenoic acid-related compounds and methods of use
    Patent number: 6353012
    Abstract: HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 5, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Mark R. Hellberg, John M. Yanni, Gustav Graff, Daniel A. Gamache, Peter G. Klimko
  • 15-ketal postaglandins for the treatment of glaucoma or ocular hypertension
    Patent number: 6353014
    Abstract: A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 5, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Mark R. Hellberg, Peter G. Klimko
  • Method of prostaglandin synthesis
    Patent number: 6344581
    Abstract: Methods of synthesizing 9-Halo-13,14-dihydroprostaglandins useful in the treatment of glaucoma and ocular hypertension are disclosed. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Raymond E. Conrow, Paul W. Zinke, Peter G. Klimko, Robert D. Selliah
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Publication number: 20020013293
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Application
    Filed: June 5, 2001
    Publication date: January 31, 2002
    Inventors: Gustav Graff, Peter G. Klimko
  • Benzenoid derivatives of 15-hydroxyeicosatetraenoic acid and methods of their use in treating dry eye disorders
    Patent number: 6342525
    Abstract: Benzenoid HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: January 29, 2002
    Assignee: Alcon Universal Ltd.
    Inventors: Peter G. Klimko, David R. Pierce
  • Heteroatom-Interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use
    Publication number: 20020002196
    Abstract: Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Application
    Filed: June 25, 2001
    Publication date: January 3, 2002
    Inventors: Raymond E. Conrow, Peter G. Klimko
  • 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use
    Patent number: 6331644
    Abstract: 3-heteroatom substituted and two carbon homologs of 15-HETE, and their derivatives, compositions and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: December 18, 2001
    Assignee: Alcon Universal Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Gustav Graff
  • Heteroatom-interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use
    Patent number: 6331566
    Abstract: Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: December 18, 2001
    Assignee: Alcon Universal Ltd.
    Inventors: Raymond E. Conrow, Peter G. Klimko
  • Heteroatom-interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use
    Publication number: 20010051648
    Abstract: Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.
    Type: Application
    Filed: June 25, 2001
    Publication date: December 13, 2001
    Inventors: Raymond E. Conrow, Peter G. Klimko
  • Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
    Publication number: 20010041692
    Abstract: Phospholipid-HETE derivatives, compositions and methods of use are disclosed. The compounds are particularly useful for treating dry eye.
    Type: Application
    Filed: June 5, 2001
    Publication date: November 15, 2001
    Inventors: Gustav Graff, Peter G. Klimko
  • Selective inhibitors of adenosine monophosphate deaminase for the treatment of optic nerve and retinal damage
    Patent number: 6300328
    Abstract: Selective AMPDA inhibitors for preventing and treating damage to the optic nerve and/or retina are disclosed.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: October 9, 2001
    Assignee: Alcon Universal Ltd.
    Inventor: Peter G. Klimko
  • Use of cis-&Dgr;4 analogs of prostaglandins as ocular hypotensives
    Patent number: 6235779
    Abstract: Cis-&Dgr;4 analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: May 22, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, Paul W. Zinke
  • 11-Aza prostaglandins for the treatment of glaucoma and ocular hypertension
    Patent number: 6211226
    Abstract: 11-aza analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: October 29, 1999
    Date of Patent: April 3, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, Peter G. Klimko
  • Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 6197812
    Abstract: Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: March 6, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert D. Selliah, Mark R. Hellberg, Peter G. Klimko, Verney L. Sallee, Paul W. Zinke
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6184250
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues and combinations thereof with other medicaments for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor. Also disclosed are methods of treating optic nerve disorders using the cloprostenol and fluprostenol analogues.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: February 6, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke, Tom R. Dean, George E. Barnes, Michael L. Chandler