Patents by Inventor Peter G. Klimko

Peter G. Klimko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Patent number: 7759333
    Abstract: The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: July 20, 2010
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Robert J. Collier, Jr., Mark R. Hellberg
  • SUPEROXIDE DISMUTASE MIMICS FOR THE TREATMENT OF OCULAR DISORDERS AND DISEASES
    Publication number: 20100179117
    Abstract: The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: March 24, 2010
    Publication date: July 15, 2010
    Applicant: ALCON, INC.
    Inventors: Peter G. Klimko, Robert J. Collier, JR., Mark R. Hellberg
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Patent number: 7754706
    Abstract: The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: July 13, 2010
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Robert J. Collier, Jr., Mark R. Hellberg
  • Method of treating dry eye disorders
    Patent number: 7745461
    Abstract: The topical use of EgLN-3 inhibitors is disclosed for the treatment of dry eye.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: June 29, 2010
    Assignee: Alcon Research, Ltd.
    Inventor: Peter G. Klimko
  • METHOD OF TREATING OCULAR ALLERGY
    Publication number: 20100160298
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Application
    Filed: February 8, 2010
    Publication date: June 24, 2010
    Applicant: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • Method of treating ocular allergy
    Patent number: 7687539
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: March 30, 2010
    Assignee: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • Histone Deacetylase Inhibitors for the Treatment of Ocular Neovascular or Edematous Disorders and Diseases
    Publication number: 20100048608
    Abstract: Ophthalmic compositions containing HDAC inhibitors and their use for treating ocular neovascular or edematous diseases and disorders are disclosed.
    Type: Application
    Filed: October 30, 2009
    Publication date: February 25, 2010
    Applicant: ALCON, INC.
    Inventors: Peter G. Klimko, David P. Bingaman
  • Method of treating glaucoma
    Patent number: 7625927
    Abstract: Described are methods for the treatment of ocular hypertension or glaucoma comprising administering a pharmaceutically effective amount of one or more compounds that inhibit the enzyme EgLN-3. Certain embodiments of the invention combine the use of EgLN-3 with other glaucoma treatment agents. The compounds of the invention may be formulated in compositions comprising pharmaceutically acceptable carriers.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: December 1, 2009
    Assignee: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Iok-Hou Pang
  • METHOD OF TREATING ASTHMA, ALLERGIC RHINITIS, AND SKIN DISORDERS
    Publication number: 20090156667
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis.
    Type: Application
    Filed: February 19, 2009
    Publication date: June 18, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard, Bryon S. Severns
  • Complement C1Q Inhibitors For The Prevention And Treatment Of Glaucoma
    Publication number: 20090117098
    Abstract: The invention concerns in one embodiment a method of treating glaucoma or elevated intraocular pressure comprising administering a pharmaceutically effective amount of a composition comprising a Complement C1q inhibitor. In another embodiment, the invention concerns a composition for the treatment of elevated intraocular pressure and glaucoma, the composition comprising a pharmaceutically effective amount of a Complement C1q inhibitor.
    Type: Application
    Filed: October 31, 2008
    Publication date: May 7, 2009
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Allan R. SHEPARD, Abbot F. Clark, Peter G. Klimko, Martin B. Wax
  • METHOD OF TREATING GLAUCOMA
    Publication number: 20070203174
    Abstract: Described are methods for the treatment of ocular hypertension or glaucoma comprising administering a pharmaceutically effective amount of one or more compounds that inhibit the enzyme EgLN-3. Certain embodiments of the invention combine the use of EgLN-3 with other glaucoma treatment agents. The compounds of the invention may be formulated in compositions comprising pharmaceutically acceptable carriers.
    Type: Application
    Filed: February 27, 2007
    Publication date: August 30, 2007
    Applicant: ALCON MANUFACTURING, LTD.
    Inventors: Peter G. KLIMKO, Iok-Hou PANG
  • Use of proteasome inhibitors to treat dry eye disorders
    Patent number: 7112588
    Abstract: Proteasome inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: September 26, 2006
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg
  • 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
    Patent number: 7060728
    Abstract: 11,12-Oxidoarachidonic acid derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: June 13, 2006
    Assignee: Alcon, Inc.
    Inventors: David B. Belanger, Peter G. Klimko
  • Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
    Patent number: 6803385
    Abstract: Hydroxyeicosatetraenoic acid esters and methods of their use in treating dry eye disorders are disclosed.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: October 12, 2004
    Assignee: Alcon, Inc.
    Inventors: Peter G. Klimko, Mark R. Hellberg, John R. Falck, Raymond E. Conrow
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Publication number: 20040198817
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Application
    Filed: April 20, 2004
    Publication date: October 7, 2004
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke, George E. Barnes, Michael L. Chandler, Thomas R. Dean, Jesse A. May, Louis Desantis
  • Use of proteasome inhibitors to treat dry eye disorders
    Publication number: 20040180859
    Abstract: Proteasome inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
    Type: Application
    Filed: March 24, 2004
    Publication date: September 16, 2004
    Inventors: Peter G. Klimko, Mark R. Hellberg
  • 11,12-Oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
    Publication number: 20040157805
    Abstract: 11,12-Oxidoarachidonic acid derivatives and methods of their use for treating dry eye are disclosed.
    Type: Application
    Filed: February 6, 2004
    Publication date: August 12, 2004
    Inventors: David B. Belanger, Peter G. Klimko
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Publication number: 20040116402
    Abstract: The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 5, 2003
    Publication date: June 17, 2004
    Inventors: Peter G. Klimko, Robert J. Collier, Mark R. Hellberg
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Publication number: 20040116403
    Abstract: The use of SOD mimics, particularly Mn(III) porphyrin complexes, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 5, 2003
    Publication date: June 17, 2004
    Inventors: Peter G. Klimko, Robert J. Collier, Mark R. Hellberg
  • 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
    Patent number: 6750250
    Abstract: 11,12-Oxidoarachidonic acid derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: June 15, 2004
    Assignee: Alcon, Inc.
    Inventors: David B. Belanger, Peter G. Klimko